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| 1 | Spatial heterogeneity and source apportionment of soil metal(loid)s in an abandoned lead/zinc smelter显示文摘Metal smelting have brought severe metal(loid)s contamination to the soil.Spatial distribution and pollution source analysis for soil metal(loid)s in an abandoned lead/zinc smelter were studied.The results showed that soil was contaminated heavily withmetal(loid)s.The mean of lead(Pb),arsenic(As),cadmium(Cd),mercury(Hg)and antimony(Sb)content in topsoil is 9.7,8.2,5.0,2.3,and 1.2 times higher than the risk screening value for soil contamination of development land of China(GB36600-2018),respectively.Cd ismainly enriched in the 0–6mdepth of site soil while As and Pbmainly deposited in the 0–4mlayer.The spatial distribution of soil metal(loid)s is significantly correlated with the pollution source in the different functional areas of smelter.As,Hg,Sb,Pb and copper(Cu)were mainly distributed in pyrometallurgical area,while Cd,thallium(Tl)and zinc(Zn)was mainly existed in both hydrometallurgical area and raw material storage area.Soil metal(loid)s pollution sources in the abandoned smelter are mainly contributed to the anthropogenic sources,accounting for 84.5%.Specifically,Pb,Tl,As,Hg,Sb and Cumainly from atmospheric deposition(55.9%),Cd and Zn mainly from surface runoff(28.6%),While nickel(Ni)mainly comes from parent material(15.5%).The results clarified the spatial distribution and their sources in different functional areas of the smelter,providing a new thought for the risk prevention and control of metal(loid)s in polluted site soil. | Yunxia Zhang Tianshuang Li Zhaohui Guo Huimin Xie Zhihao Hu Hongzhen Ran Changzhou Li Zhichao Jiang | 2023 | Journal of Environmental Sciences2023，，5： | 5 |
| 2 | Bioaccessibility and health risk of arsenic and heavy metals (Cd, Co, Cr, Cu, Ni, Pb, Zn and Mn) in TSP and PM2.5 in Nanjing, China显示文摘 | Xin Hu Yun Zhang Zhuhong Ding Tijian Wang Hongzhen Lian Yuanyuan Sun Jichun Wu | 2012 | Atmospheric Environment2012，，： | 2 |
| 3 | Lead contamination and transfer in urban environmental compartments analyzed by lead levels and isotopic compositions显示文摘 | Xin Hu Yuanyuan Sun Zhuhong Ding Yun Zhang Jichun Wu Hongzhen Lian Tijian Wang | 2014 | Environmental Pollution2014，，： | 1 |
| 4 | Serine proteases excite myenteric neurons through protease-activated receptors in guinea pig small intestine 显示文摘 | Gao Chuanyun Liu Sumei Hu Hongzhen | 2002 | Gastroenterology2002，123，5： | 1 |
| 5 | Activation of TRPA1 channels by fenamate nonsteroidal anti-inflammatory drugs显示文摘 | Hongzhen Hu Jinbin Tian Yingmin Zhu Chunbo Wang Rui Xiao Jeffrey M. Herz Jackie D. Wood Michael X. Zhu | 2010 | Pflügers Archiv - European Journal of Physiology2010，，： | 1 |
| 6 | Pore region of TRPV3 ion channel is specifically required for heat activation显示文摘 | Jorg Grandl Hongzhen Hu Michael Bandell | 2008 | Nat Neurosci2008，11，9： | 1 |
| 7 | Bioaccessibility and health risk of arsenic and heavy metals (Cd, Co, Cr, Cu, Ni, Pb, Zn and Mn) in TSP and PM2.5 in Nanjing, China显示文摘 | Xin Hu Yun Zhang Zhuhong Ding Tijian Wang Hongzhen Lian Yuanyuan Sun Jichun Wu | 2012 | Atmospheric Environment2012，，： | 1 |
| 8 | Interfacial enhancement of carbon fiber composites by poly(amido amine) functionalization显示文摘 | Qingyu Peng Yibin Li Xiaodong He Hongzhen Lv Pingan Hu Yuanyuan Shang Chao Wang Rongguo Wang Thirumany Sritharan Shanyi Du | 2013 | Composites Science and Technology2013，，： | 1 |
| 9 | Bioaccessibility and health risk of arsenic and heavy metals (Cd, Co, Cr, Cu, Ni, Pb, Zn and Mn) in TSP and PM2.5 in Nanjing, China显示文摘 | Xin Hu Yun Zhang Zhuhong Ding Tijian Wang Hongzhen Lian Yuanyuan Sun Jichun Wu | 2012 | Atmospheric Environment2012，，： | 1 |
| 10 | Bioaccessibility and health risk of arsenic and heavy metals (Cd, Co, Cr, Cu, Ni, Pb, Zn and Mn) in TSP and PM2.5 in Nanjing, China显示文摘 | Xin Hu Yun Zhang Zhuhong Ding Tijian Wang Hongzhen Lian Yuanyuan Sun Jichun Wu | 2012 | Atmospheric Environment2012，，： | 1 |
| 11 | Fast Zn^(2+)mobility enabled by sucrose modified Zn^(2+)solvation structure for dendrite-free aqueous zinc battery显示文摘Aqueous zinc battery has been regarded as one of the most promising energy storage systems due to its low cost and environmental benignity.However,the safety concern on Zn anodes caused by uncontrolled Zn dendrite growth in aqueous electrolyte hinders their application.Herein,sucrose with multi-hydroxyl groups has been introduced into aqueous electrolyte to modify Zn^(2+)solvation environment and create a protection layer on Zn anode,thus effectively retarding the growth of zinc dendrites.Atomistic simulations and experiments confirm that sucrose molecules can enter into the solvation sheath of Zn^(2+),and the as-formed unique solvation structure enhances the mobility of Zn^(2+).Such fast Zn^(2+)kinetics in sucrose-modified electrolyte can successfully suppress the dendrite growth.With this sucrose-modified aqueous electrolyte,Zn/Zn symmetric cells present more stable cycle performance than those using pure aqueous electrolyte;Zn/C cells also deliver an impressive higher energy density of 129.7 Wh·kg^(−1)and improved stability,suggesting a great potential application of sucrose-modified electrolytes for future Zn batteries. | Yufang Cao Xiaohui Tang Linge Li Haifeng Tu Yuzhen Hu Yingying Yu Shuang Cheng Hongzhen Lin Liwen Zhang Jiangtao Di Yongyi Zhang Meinan Liu | 2023 | Nano Research2023，16，3： | 0 |
| 12 | A Recessive Mutant of argonaute 1b/gsnl4 Leads to Narrow Leaf, Small Grain Size and Low Seed Setting in Rice显示文摘A gsnl4 mutant characterized by small grain size,narrow leaf and low seed-setting rate was obtained by ethyl methane sulfonate(EMS)mutagenesis of a japonica rice variety Wuyunjing 21.Genetic analysis showed that gsnl4 is a loss-of-function mutant.A single-base mutation in gsnl4 resulted in the substitution of Ser to Asn in the Piwi domain of OsAGOlb protein.CRISPR/Cas9-mediated editing of OsAGOlb yielded a mutant phenotypically resembling gsnl4.Furthermore,miRNA-Seq analysis showed that the transcript expression levels of miRNAs in the signal transduction pathways related to pollen development,leaf morphology and honnone activation were significantly different between the gsnl4 mutant and the wild type(WT)plants.Several miRNAs were downregulated,and their target genes were upregulated in gsnl4 mutants.The auxin content in the root tips of the gsnl4 mutant decreased,and the expression of most auxin-related genes was altered.In summary,GSNL4 not only regulates organ development by controlling cell division and expansion,but also plays an important role in regulating auxin transport in rice. | SONG Mengqiu RUAN Shuang PENG Youlin WANG Zhongwei Jahan NOUSHIN ZHANG Yu CUI Yongtao HU Haitao JIANG Hongzhen DING Shilin SHEN Lan GAO Zhenyu HU Xingming QIAN Qian GUO Longbiao | 2021 | Rice science2021，28，6： | 0 |
| 13 | Room temperature spontaneous surface condensation of boronic acids observed by scanning tunneling microscopy显示文摘Herein,we discovered that the surface-confined condensation of boronic acid can happen spontaneously at room temperature,by comparing the kinetics of condensation of boronic acids with and without the negative sample bias,we found that the negative sample bias indeed accelerates the self-condensation reaction of boronic acid.Combining with in-situ STM images and ultraviolet photoemission spectrum(UPS)analysis,a reversible adsorption mechanism model was proposed and reasonably explains the reversible electric-field-induced phase transformation. | Qiu Liang Guangyuan Feng Hongzhen Ni Yaru Song Xinyu Zhang Shengbin Lei Wenping Hu | 2023 | Chinese Chemical Letters2023，34，8： | 0 |
| 14 | EQUIAXED REFINEMENT OF GRAINS IN ALLOY TC11显示文摘The formation reason and elimination method of non-uniform microstructure defects in Ti al-loy TC11 bar have been studied.The coagulating and coarsening into block of the part ofgrain boundary α and secondary α seem to be caused by the ingot cogging and initial forgingtemperature in the β region as well as no more enough deformation and uneven distribution.The grain α,elongated α and blocky α may be finally eliminated by adopting the technique of(α+β)thermomechanical processing+β processing,W.Q.+recrystallization annealing,A.C.,thus the size of uniform and fine equiaxed α structure is believed to be reduced to 1.9258μm. | SU Zuwu MENG Guowen GUO Hongzhen LIU Jianchao YAO Zekun Northwestern Polytechnical University,Xi’an,ChinaYANG Zhaosu HU Zongshi Baoji Non-Ferrous Metals Mill,Baoji,China | 1992 | Acta Metallurgica Sinica(English Letters)1992，5，8： | 0 |
| 15 | Nociceptors and Macrophages in Bacterial Meningitis:Partners in Crime?显示文摘Bacterial meningitis is a serious and potentially life-threatening infection that affects the protective layers surrounding the brain and spinal cord,known as the meninges.Several types of bacteria,including Streptococcus pneumoniae,Neisseria meningitidis,and Haemophilus influenzae,can cause this condition.Certain populations,such as infants,children,immunocompromised adults,and the elderly,are particularly vulnerable to these pathogens.Symptoms of bacterial meningitis can manifest suddenly and may include high fever,severe and persistent headache,stiff neck,vomiting,sensitivity to light,and confusion or changes in mental state[1,2].Identifying these symptoms in infants can be more challenging and may lead to long-term disability or death[3].Despite the effectiveness of vaccines,it is crucial to understand how bacteria invade the brain and how our innate immune system responds to infection(Fig.1). | Fang Gao Hongzhen Hu | 2024 | Neuroscience Bulletin2024，40，3： | 0 |
| 16 | Highly pathogenic coronavirus N protein aggravates inflammation by MASP-2-mediated lectin complement pathway overactivation显示文摘Excessive inflammatory responses contribute to the pathogenesis and lethality of highly pathogenic human coronaviruses,but the underlying mechanism remains unclear.In this study,the N proteins of highly pathogenic human coronaviruses,including severe acute respiratory syndrome coronavirus(SARS-CoV),middle east respiratory syndrome coronavirus(MERS-CoV)and severe acute respiratory syndrome coronavirus 2(SARS-CoV-2),were found to bind MASP-2,a key serine protease in the lectin pathway of complement activation,resulting in excessive complement activation by potentiating MBL-dependent MASP-2 activation,and the deposition of MASP-2,C4b,activated C3 and C5b-9.Aggravated inflammatory lung injury was observed in mice infected with adenovirus expressing the N protein.Complement hyperactivation was also observed in SARS-CoV-2-infected patients.Either blocking the N protein:MASP-2 interaction,MASP-2 depletion or suppressing complement activation can significantly alleviate N protein-induced complement hyperactivation and lung injury in vitro and in vivo.Altogether,these data suggested that complement suppression may represent a novel therapeutic approach for pneumonia induced by these highly pathogenic coronaviruses. | Ting Gao Lin Zhu Hainan Liu Xiaopeng Zhang Tingting Wang Yangbo Fu Hongzhen Li Qincai Dong Yong Hu Zhang Zhang Jing Jin Zijing Liu Weihong Yang Yaoning Liu Yanwen Jin Kaitong Li Yongjiu Xiao Junli Liu Huailong Zhao Yue Liu Ping Li Jibo Song Lu Zhang Yuwei Gao Sisi Kang Shoudeng Chen Qingjun Ma Xiuwu Bian Wei Chen Xuan Liu Qing Mao Cheng Cao | 2022 | Signal Transduction and Targeted Therapy2022，7，10： | 0 |
| 17 | Identification of Green-Revertible Yellow 3(GRY3),encoding a 4-hydroxy-3-methylbut-2-enyl diphosphate reductase involved in chlorophyll synthesis under high temperature and high light in rice显示文摘Chlorophyll,a green pigment in photosynthetic organisms,is generated by two distinct biochemical pathways,the tetrapyrrole biosynthetic pathway(TBP) and the methylerythritol 4-phosphate(MEP)pathway.MEP is one of the pathways for isoprenoid synthesis in plants,with 4-hydroxy-3-methylbut-2-enyl diphosphate reductase(HDR) catalyzing its last step.In this study,we isolated a greenrevertible yellow leaf mutant gry3 in rice and cloned the GRY3 gene,which encodes a HDR participating in geranylgeranyl diphosphate(GGPP) biosynthesis in chloroplast.A complementation experiment confirmed that a missense mutation(C to T) in the fourth exon of LOC_Os03g52170 causes the gry3 phenotype.Under high temperature and high light,transcript and protein abundances of GRY3 were reduced in the gry3 mutant.Transcriptional expression of chlorophyll biosynthesis,chloroplast development,and genes involved in photosynthesis were also affected.Excessive reactive oxygen species accumulation,cell death,and photosynthetic proteins degradation were occurred in the mutant.The content of GGPP was reduced in gry3 compared with Nipponbare,resulting in a stoichiometric imbalance of tetrapyrrolic chlorophyll precursors.These results shed light on the response of chloroplast biogenesis and maintenance in plants to high-temperature and high-light stress. | Hongzhen Jiang Anpeng Zhang Banpu Ruan Haitao Hu Rui Guo Jingguang Chen Qian Qian Zhenyu Gao | 2023 | The Crop Journal2023，11，4： | 0 |
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