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| 1 | Adaptive Fuzzy Dynamic Surface Control of Flexible-Joint Robot Systems With Input Saturation显示文摘In this paper, we propose an adaptive fuzzy dynamic surface control(DSC) scheme for single-link flexible-joint robotic systems with input saturation. A smooth function is utilized with the mean-value theorem to deal with the difficulties associated with input saturation. An adaptive DSC design with an auxiliary first-order filter is used to solve the 'explosion of complexity'problem. It is proved that all the signals in the closed-loop system are semi-globally uniformly ultimately bounded, and the tracking error eventually converges to a small neighborhood around zero. The main advantage of the proposed method is that only one adaptation parameter needs to be updated,which reduces the computational burden significantly. Simulation results demonstrate the feasibility of the proposed scheme and the comparison results show that the improved DSC method can reduce the computational burden by almost two thirds in comparison with the standard DSC method. | Song Ling Huanqing Wang Peter X.Liu | 2019 | IEEE/CAA Journal of Automatica Sinica2019，6，1： | 22 |
| 2 | Admission clinical characteristics and early clinical outcomes among acute ischemic stroke patients显示文摘The purpose of the present study was to investigate the association between admission clinical characteristics and outcomes at discharge among acute ischemic stroke patients in the Chinese population.A total of 2,673 patients with acute ischemic stroke were included in the present study.The clinical characteristics at admission and other study variables were collected for all patients.The study outcome was defined as neurological deficiency(National Institute of Health Stroke Scale score ≥ 10) at discharge or in-hospital death.Compared with the subjects without neurological deficiency at discharge or in-hospital death,the subjects with neurological deficiency at discharge or in-hospital death had a significantly higher prevalence of hyperglycemia or history of atrial fibrillation at admission.Age≥ 80 years,hyperglycemia,hypertension,and history of atrial fibrillation were significantly associated with neurological deficiency at discharge or in-hospital death after adjustment for other variables.It is concluded that old age(≥ 80 years),hyperglycemia,hypertension and history of atrial fibrillation are significantly associated with neurological deficiency at discharge or in-hospital death among patients with acute ischemic stroke. | Xin Gao Jintao Zhang Ying Peng Huanqing Fan Mei Chen Tan Xu Yonghong Zhang | 2012 | The Journal of Biomedical Research2012，26，3： | 13 |
| 3 | Approximation-based adaptive fuzzy control for a class of non-strict-feedback stochastic nonlinear systems显示文摘This paper considers the problem of adaptive fuzzy control of a class of single-input/single-output(SISO)nonlinear stochastic systems in non-strict-feedback form.Fuzzy logic systems are used to approximate the uncertain nonlinearities and backstepping technique is utilized to construct an adaptive fuzzy controller.The proposed controller guarantees that all the signals in the resulting closed-loop system are bounded in probability.The main contribution of this note lies in providing a control strategy for a class of nonlinear systems in non-strict-feedback form.Simulation result is used to test the efectiveness of the suggested approach. | WANG HuanQing CHEN Bing LIN Chong | 2014 | Science China(Information Sciences)2014，57，3： | 12 |
| 4 | Integrated transcriptomic and metabolomic analyses of a wax deficient citrus mutant exhibiting jasmonic acid-mediated defense against fungal pathogens显示文摘Naturally,resistant crop germplasms are important resources for managing the issues of agricultural product safety and environment deterioration.We found a spontaneous mutant of‘Newhall’navel orange(Citrus sinensis Osbeck)(MT)with broad-spectrum protections against fungal pathogens in the orchard,postharvest-storage,and artificial inoculation conditions.To understand the defense mechanism of MT fruit,we constructed a genome-scale metabolic network that integrated metabolome and transcriptome datasets.The coordinated transcriptomic and metabolic data were enriched in two sub-networks,showing the decrease in very long chain fatty acid(by 41.53%)and cuticular wax synthesis(by 81.34%),and increase in the synthesis of jasmonic acid(JA)(by 95.23%)and JA-induced metabolites such as 5-dimethylnobietin(by 28.37%)in MT.Furthermore,cytological and biochemical analyses confirmed that the response to fungal infection in MT was independent of wax deficiency and was correlated with the levels of jasmonates,and the expression of plant defensin gene PDF1.2.Results of exogenous application of MeJA and JA inhibitors such as propyl gallate proved that JA-mediated defense contributes to the strong tolerance against pathogens in MT.Our results indicated that jasmonate biosynthesis and signaling are stimulated by the fatty acid redirection of MT,and participate in the tolerance of pathogenic fungi. | Yizhong He Jingwen Han Runsheng Liu Yuduan Ding Jinqiu Wang Li Sun Xiaoming Yang Yunliu Zeng Weiwei Wen Juan Xu Hongming Zhang Xiang Yan Zhaoxing Chen Zuliang Gu Hong Chen Huanqing Tang Xiuxin Deng Yunjiang Cheng | 2018 | Horticulture Research2018，5，1： | 8 |
| 5 | Prevalence and Risk Factors of Anemia of Pregnant Women--6 Provinces in China,2014−2018显示文摘What is already known about this topic?Anemia during pregnancy is a global public health problem affecting both maternal and children’s health.The“National Nutrition Plan(2017–2030)”and“Healthy China Action(2019–2030)”issued by the State Council of China in 2017 and 2019,respectively,specified nutrition targets:by 2030,the anemia rate in pregnant women should be reduced to less than 10%.The anemia prevalence of pregnant women reported by the Chinese Nutrition and Health Surveillance in 2006 and 2010–2012 was 42.0%and 17.2%,respectively.What is added by this report?Past surveillance in 2010–2012 did not divide pregnant women by gestation week,and the sample size was only 4,315 cases.In this study,the information of 206,753 registered pregnant women from their first antenatal care(ANC)examination to childbirth was collected from 2014 to 2018.The overall prevalence of anemia among pregnant women was 41.98%.What are the implications for public health practice?The overall prevalence of anemia among pregnant women in the monitoring areas was high,far from the target of 10%.Anemia remains a serious health problem among pregnant women in China.It is urgent to develop effective strategies and take measures to reduce the prevalence of anemia in China. | Huanqing Hu Aiqun Huang Qi Yang Wei Zhao Yu Ma Jiangli Di | 2020 | China CDC weekly2020，2，14： | 7 |
| 6 | Localization in 3D Sensor Networks Using Stochastic Particle Swarm Optimization显示文摘Localization is one of the key technologies in wireless sensor networks,and the existing PSO-based localization methods are based on standard PSO,which cannot guarantee the global convergence.For the sensor network deployed in a three-dimensional region,this paper proposes a localization method using stochastic particle swarm optimization.After measuring the distances between sensor nodes,the sensor nodes estimate their locations using stochastic particle swarm optimization,which guarantees the global convergence of the results.The simulation results show that the localization error of the proposed method is almost 40% of that of multilateration,and it uses about 120 iterations to reach the optimizing value,which is 80 less than the standard particle swarm optimization. | ZHANG Zhangxue CUI Huanqing | 2012 | Wuhan University Journal of Natural Sciences2012，17，6： | 7 |
| 7 | Fine Stratigraphic Division of Volcanic Reservoir by Uniting of Well Data and Seismic Data—Taking Volcanic Reservoir of Member One of Yingcheng Formation in Xudong Area of Songliao Basin for an Example显示文摘Taking member one of Yingcheng Formation of Cretaceous in Xudong area, Xushen Gas Field of Songliao Basin for an example and aimed at the diachronous problem generally existed in volcanic reservoir division, firstly advanced the method of two steps and two unites in the researches of volcanic reservoir finely division that guided by the method that sources controlled and founded the stratigraphic trellis. In this process, volcanic edifices and bodies were identified and traced. The results indicated that aimed strata in study areas could be carved up to six layers of YC1I1, YC1I2, YC1I-II, YC1II1, YC1II2 and YC1III from the top to the bottom. Analyzing causes and firmly united of well data and seismic data could achieve fine stratigraphic division of volcanic reservoir. Surfaces of layers and volcanic bodies were basically unanimous in side direction. Stratum inclination gradually reduced with the distances increased from craters. The results of volcanic reservoir division had preferable consistency with lithologies and volcanic lithofacies and dynamic development data. The researches offered a useful method to stratigraphic division of volcanic reservoir and it had very important significance to effective development of volcanic reservoir in practice. | Huanqing Chen Yongle Hu Jiuqiang Jin Qiquan Ran Lin Yan | 2014 | Journal of Earth Science2014，25，2： | 5 |
| 8 | Pm67, a new powdery mildew resistance gene transferred from Dasypyrum villosum chromosome 1V to common wheat(Triticum aestivum L.)显示文摘Powdery mildew, caused by the biotrophic fungus Blumeria graminis f. sp. tritici(Bgt), is a global disease that poses a serious threat to wheat production. To explore additional resistance gene, a wheatDasypyrum villosum 1 V#5(1 D) disomic substitution line NAU1813(2 n = 42) with high level of seedling resistance to powdery mildew was used to generate the recombination between chromosomes 1 V#5 and1 D. Four introgression lines, including t1 VS#5 ditelosomic addition line NAU1815, t1 VL#5 ditelosomic addition line NAU1816, homozygous T1 DL·1 VS#5 translocation line NAU1817, and homozygous T1 DS·1 VL#5 translocation line NAU1818 were developed from the selfing progenies of 1 V#5 and 1 D double monosomic line that derived from F1 hybrids of NAU1813/NAU0686. All of them were characterized by fluorescence in situ hybridization, genomic in situ hybridization, 1 V-specific markers analysis, and powdery mildew tests at different developmental stages. A new powdery mildew resistance gene named Pm67 was physically located in the terminal bin(FL 0.70–1.00) of 1 VS#5. Lines with Pm67 exhibited seedling stage immunity and tissue-differentiated reactions at adult plant stage. The sheaths, stems, and spikes of the Pm67 line were still immune, but the leaves showed a low degree of susceptibility.Microscopic observation showed that most penetration attempts were stopped in association with papillae on the sheath, and colonies cannot form conidia on the susceptible leaf of Pm67 line at adult plant stage, suggesting that the defence layers of the Pm67 line is tissue-differentiated. Thus, the T1 DL·1 VS#5 translocation line NAU1817 provides a new germplasm in wheat breeding for improvement of powdery mildew resistance. | Ruiqi Zhang Chuanxi Xiong Huanqing Mu Ruonan Yao Xiangru Meng Lingna Kong Liping Xing Jizhong Wu Yigao Feng Aizhong Cao | 2021 | The Crop Journal2021，9，4： | 3 |
| 9 | Incidence and Risk Factors of Hypertensive Disorders of Pregnancy—8 Provinces,China,2014–2018显示文摘Summary What is already known about this topic?As a major cause of maternal and neonatal mortality and morbidity,hypertensive disorders of pregnancy(HDP)are a global public health problem affecting maternal and children’s health.What is added by this report?The incidence of HDP was 6.40%among 277,632 pregnant women.With the progress of pregnancy,the proportion of pregnant women with high normal blood pressure(BP)and the incidence of HDP increased gradually.The incidence of HDP increased with pregnancy age,body mass index,and BP of pregnant women during first trimester.What are the implications for public health practice?To reduce the incidence of HDP effectively,we should pay more attention to older women who plan to become pregnant,measures should be taken to control BP and weight in pre-pregnancy. | Wei Zhao Jiangli Di Aiqun Huang Qi Yang Huanqing Hu | 2021 | China CDC weekly2021，3，22： | 3 |
| 10 | Finite-time Adaptive Fault-tolerant Control for Nonlinear Systems With Multiple Faults显示文摘This paper focuses on the problem of adaptive finitetime fault-tolerant control for a class of non-lower-triangular nonlinear systems.The faults encountered in the control system include the actuator faults and the abrupt system fault.By applying backstepping design and neural networks approximation,an adaptive finite-time fault-tolerant control scheme is developed.It is shown that the proposed controller ensures that all signals in the closed-loop system are semi-globally practically finite-time stable and the track-ing error converges to a small neighborhood around the origin within finite time.The simulation is carried out to explain the validity of the developed strategy. | Huanqing Wang Wen Bai Peter Xiaoping Liu | 2019 | IEEE/CAA Journal of Automatica Sinica2019，6，6： | 3 |
| 11 | Study of brain morphology change in Alzheimer’s disease and amnestic mild cognitive impairment compared with normal controls显示文摘Background With an aggravated social ageing level, the number of patients with Alzheimer's disease (AD) is gradually increasing, and mild cognitive impairment (MCI) is considered to be an early form of Alzheimer's disease. How to distinguish diseases in the early stage for the purposes of early diagnosis and treatment is an important topic. Aims The purpose of our study was to investigate the differences in brain cortical thickness and surface area among elderly patients with AD, elderly patients with amnestic MCI (aMCI) and normal controls (NC). Methods 20 AD patients, 21 aMCIs and 25 NC were recruited in the study. FreeSurfer software was used to calculate cortical thickness and surface area among groups. Results The patients with AD had less cortical thickness both in the left and right hemisphere in 17 of the 36 brain regions examined than the patients with aMCI or NC. The patients with AD also had smaller cerebral surface area both in the left and right hemisphere in 3 of the 36 brain regions examined than the patients with aMCI or NC. Compared with the NC, the patients with aMCI only had slight atrophy in the inferior parietal lobe of the left hemisphere, and no significant difference was found. Conclusion AD, as well as aMCI (to a lesser extent), is associated with reduced cortical thickness and surface area in a few brain regions associated with cognitive impairment. These results suggest that cortical thickness and surface area could be used for early detection of AD. | Huanqing Yang Hua Xu Qingfeng Li Yan Jin Weixiong Jiang Jinghua Wang Yina Wu Wei Li Cece Yang Xia Li Shifu Xiao Feng Shi Tao Wang | 2019 | General Psychiatry2019，32，2： | 3 |
| 12 | A stage-specific cell-manipulation platform for inducing endothelialization on demand显示文摘Endothelialization is of great significance for vascular remodeling,as well as for the success of implanted vascular grafts/stents in cardiovascular disease treatment.However,desirable endothelialization on synthetic biomaterials remains greatly challenging owing to extreme difficulty in offering dynamic guidance on endothelial cell(EC)functions resembling the native extracellular matrix-mediated effects.Here,we demonstrate a bilayer platform with near-infrared-triggered transformable topographies,which can alter the geometries and functions of human ECs by tunable topographical cues in a remote-controlled manner,yet cause no damage to the cell viability.The migration and the adhesion/spreading of human ECs are respectively promoted by the temporary anisotropic and permanent isotropic topographies of the platform in turn,which appropriately meet the requirements of stage-specific EC manipulation for endothelialization.In addition to the potential of promoting the development of a new generation of vascular grafts/stents enabling rapid endothelialization,this stage-specific cell-manipulation platform also holds promise in various biomedical fields,since the needs for stepwise control over different cell functions are common in wound healing and various tissue-regeneration processes. | Qilong Zhao Juan Wang Yunlong Wang Huanqing Cui Xuemin Du | 2020 | National Science Review2020，7，3： | 3 |
| 13 | Interfacial characteristics and mechanical properties of additive manufacturing martensite stainless steel on the Cu-Cr alloy substrate by directed energy deposition显示文摘Copper/steel is a typical bimetal functional material,combining the excellent electrical and thermal conductivity of copper alloy and the high strength and hardness of stainless steel.There has been recent interest in manufacturing copper/steel bimetal by directed energy deposition(DED)due to its layer-bylayer method.However,cracks tend to form on the copper/steel interface because of the great difference in thermal expansion coefficient and crystal structure between copper and steel.In this work,interfacial characteristics and mechanical properties of the copper/steel bimetal were studied from one layer to multilayers.The laser power has a great influence on the Cu element distribution of the molten pool,affecting the crack formation dramatically on the solidification stage.Cracks tend to form along columnar grain boundaries because of the Cu-rich liquid films and spherical particles in the cracks.Crack-free and good metallurgical bonding copper/steel interface is formed at a scanning velocity of 800 mm/min and the laser power of 3000 W.The ultimate tensile strength(UTS)and the break elongation(EL)of the vertically combined crack-free copper/steel bimetal are 238.2±4.4 MPa and 20.6±0.7%,respectively.The fracture occurs on the copper side instead of the copper/steel interface,indicating that the bonding strength is higher than that of the Cu-Cr alloy.The UTS of the horizontally combined crack-free copper/steel bimetal is 746.7±22.6 MPa,which is 200%higher than that of the Cu-Cr alloy substrate.The microhardness is 398.6±5.4 HV at the steel side and is 235.3±64.1 HV at the interface,which is400%higher than that of the Cu-Cr alloy substrate.This paper advances the understanding of the interfacial characteristics of heterogeneous materials and provides guidance and reference for the fabrication of multi-material components by DED. | Wenqi Zhang Hailong Liao Zhiheng Hu Shasha Zhang Baijin Chen Huanqing Yang Yun Wang Haihong Zhu | 2021 | Journal of Materials Science & Technology2021，，31： | 2 |
| 14 | Nitric oxide enhances the sensitivity of alpaca melanocytes to respond to α-melanocyte-stimulating hormone by up-regulating melanocortin-1 receptor显示文摘 | Yanjun Dong Jing Cao Haidong Wang Jie Zhang Zhiwei Zhu Rui Bai HuanQing Hao Xiaoyan He Ruiwen Fan Changsheng Dong | 2010 | Biochemical and Biophysical Research Communications2010，，4： | 2 |
| 15 | Microstructure and Mechanical Properties of Hot Pressed TiB_2-ZrO_2 Composites显示文摘The partially stabilized ZrO_2(PSZ) particles were introduced into TiB_2 ceramics to improve its density and mechanical properties.The results show that the addition of PSZ is very effective not only in bettering the sinterabiiity but also in enhancing the flexural strength and fracture toughness of TiB_2. | Ge Qilu Han Huanqing Liang Xiaoying Wu Wenfang Wu Weihang | 1996 | Journal of Iron and Steel Research(International)1996，3，2： | 2 |
| 16 | miR-497 regulates neuronal death in mouse brain after transient focal cerebral ischemia 显示文摘 | Yin K J Denq Z Huanq H | 2010 | Neurobiol Dis2010，38，1： | 1 |
| 17 | Analysis of Project Delivery Systems in Chinese Construction Industry with Data Envelopment Analysis(DEA)显示文摘 | YONG Q C HUANQING L WENXUE L | 2010 | Engineering Construction and Architechmal Management2010，17，6： | 1 |
| 18 | Grid-connected inverter for wind power generation system显示文摘 | Yang Yong Ruan Yi Shen Huanqing | 2009 | Journal of Shanghai University2009，13，1： | 1 |
| 19 | Chrysophanol induces nec- rosis through the production of ROS and alteration of ATP levels in human liver cancer cells 显示文摘 | Lu C C Yang J S Huanq A C | 2010 | Mol Nutr Food Res2010，18，12： | 1 |
| 20 | Chemical modification patterns compatible with high potency dicer-substrate smaU interfering RNAs 显示文摘 | Collingwood MA Rose SD Huanq L | 2005 | Oligonucleotides2005，18，2： | 1 |
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