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| 1 | Surgical treatment of hepatocellular carcinoma with severe intratumoral arterioportal shunt显示文摘We report a case of hepatocellular carcinoma (HCC) that caused a severe arterioportal shunt (APS). A 49-year-old man was admitted to hospital due to esophagogastric variceal hemorrhage and HCC, and underwent endoscopic variceal ligation (EVL) and endoscopic injection sclerotherapy (EIS). He was then referred to our hospital. Abdominal computed tomography revealed a lowdensity lesion in the posterior segment of the liver and an intratumoral APS, which caused portal hypertension. Although the patient underwent EVL, EIS, Hassab’s operation, and transcatheter arterial embolization for APS, he vomited blood due to rupture of esophagogastric varices. Right hepatectomy was performed for the treatment of HCC and APS, although the indocyanine green retention value at 15 min after intravenous injection was poor (30%). The patient’s postoperative course was uneventful. Eventually, APS disappeared and the esophagogastric varices improved. | Hiromichi Ishii Teruhisa Sonoyama Shingo Nakashima Hiroyuki Nagata Atsushi Shiozaki Yoshiaki Kuriu Hisashi Ikoma Masayoshi Nakanishi Daisuke Ichikawa Hitoshi Fujiwara Kazuma Okamoto Toshiya Ochiai Yukihito Kokuba Chohei Sakakura Eigo Otsuji | 2010 | World Journal of Gastroenterology2010，16，25： | 11 |
| 2 | Feasibility of initial endoscopic common bile duct stone removal in patients with acute cholangitis显示文摘AIM To investigate the feasibility of initial endoscopic common bile duct(CBD) stone removal in patients with acute cholangitis(AC).METHODS A single-center,retrospective study was conducted between April 2013 and December 2014 and was approved by the Medical Ethics Committee at our institution.Written informed consent was obtained from each patient prior to the procedure.The cohort comprised 31 AC patients with CBD stones who underwent endoscopic biliary drainage(EBD) for na?ve papilla within 48 h after AC onset.We retrospectively divided the participants into two groups: 19 patients with initial endoscopic CBD stone removal(initial group) and 12 patients with delayed endoscopic CBD stone removal(delayed group).We evaluated the feasibility of initial endoscopic CBD stone removal in patients with AC.RESULTS We observed no significant differences between the groups regarding patient characteristics.According to the assessments based on the Tokyo Guidelines,the AC severity of patients with initial endoscopic CBD stone removal was mild to moderate.The use of antithrombotic agents before EBD was less frequent in the initial group than in the delayed group(11% vs 58%,respectively; P = 0.004).All the patients underwent successful endoscopic CBD stone removaland adverse events did not differ significantly between the groups.The number of endoscopic retrograde cholangiopancreatography procedures was significantly lower in the initial group than in the delayed group [median(interquartile range) 1(1-1) vs 2(2-2),respectively; P < 0.001].The length of hospital stay was significantly shorter for the initial group than for the delayed group [10(9-15) vs 17(14-20),respectively; P = 0.010].CONCLUSION Initial endoscopic CBD stone removal in patients with AC may be feasible when AC severity and the use of antithrombotic agents are carefully considered. | Akira Yamamiya Katsuya Kitamura Yu Ishii Yuta Mitsui Tomohiro Nomoto Hitoshi Yoshida | 2017 | World Journal of Clinical Cases2017，5，7： | 5 |
| 3 | Clinical outcomes of endoscopic ultrasonography-guided transmural drainage using plastic stent and nasocystic drain for pancreatic and peripancreatic collections显示文摘To the Editor:Pancreatic and peripancreatic collections(PCs)develop from acute pancreatitis(AP),chronic pancreatitis,surgery,or trauma.The 2012 revised Atlanta classification[1]of AP classified local complications into the following 4 PC types:acute peripancreatic fluid collection(<4 weeks after the onset of acute interstitial edematous pancreatitis),acute necrotic collection(<4 weeks after the onset of acute necrotizing pancreatitis),pancreatic pseudocyst(PPC;≥4 weeks after the onset of acute interstitial edematous pancreatitis),and walled-off necrosis(WON;≥4 weeks after the onset of acute necrotizing pancreatitis).Endoscopic ultrasonographyguided transmural drainage(EUS-TD)has been reported to be a minimally invasive procedure for patients with PCs[2–4].This study aimed to investigate the clinical outcomes of EUS-TD for PCs. | Katsuya Kitamura Akira Yamamiya Yu Ishii Yuta Mitsui Hitoshi Yoshida | 2019 | Hepatobiliary & Pancreatic Diseases International2019，18，1： | 2 |
| 4 | Apparent diffusion coefficient value reflects invasive and proliferative potential of bladder cancer显示文摘 | Shuichiro Kobayashi Fumitaka Koga Kohei Kajino Soichiro Yoshita Chikako Ishii Hiroshi Tanaka Kazutaka Saito Hitoshi Masuda Yasuhisa Fujii Tetsuo Yamada Kazunori Kihara | 2014 | Imaging2014，，1： | 2 |
| 5 | Evaluation of diagnostic cytology via endoscopic naso-pancreatic drainage for pancreatic tumor显示文摘AIM: To evaluate the usefulness of cytology of the pancreatic juice obtained via the endoscopic naso-pancreatic drainage tube(ENPD-C).METHODS: ENPD was performed in cases where a diagnosis could not be made other than by using en-doscopic retrograde cholangiopancreatography and in cases of pancreatic neoplasms or cystic tumors, includ-ing intraductal papillary mucinous neoplasm(IPMN) suspected to have malignant potential. 35 patients(21 males and 14 females) underwent ENPD between January 2007 and June 2013. The pancreatic duct was imaged and the procedure continued in one of ENPD-C or ENPD-C plus brush cytology(ENPD-BC). We checked the cytology result and the final diagnosis.RESULTS: The mean patient age was 69 years(range, 48-86 years). ENPD-C was performed in 24 cases andENPD-C plus brush cytology(ENPD-BC) in 11 cases. The ENPD tube was inserted for an average of 3.5 d. The final diagnosis was confirmed on the basis of the resected specimen in 18 cases and of follow-up findings at least 6 mo after ENPD in the 18 inoperable cases. Malignancy was diagnosed in 21 cases and 14 patients were diagnosed as having a benign condition. The ratios of class Ⅴ/Ⅳ:Ⅲ:Ⅱ/Ⅰ?findings were 7:7:7 in malignant cases and 0:3:11 in benign cases. The sensitivity and specificity for all patients were 33.3% and 100%, re-spectively. The cytology-positive rate was 37.5%(6/16) for pancreatic cancer. For IPMN cases, the sensitivity and specificity were 33% and 100%, respectively.CONCLUSION: Sensitivity may be further increased by adding brush cytology. Although we can diagnosis cancer in cases of a positive result, the accuracy of ENPD-C remains unsatisfactory. | Tomoyuki Iwata Katsuya Kitamura Akira Yamamiya Yu Ishii Yoshiki Sato Tomohiro Nomoto Akitoshi Ikegami Hitoshi Yoshida | 2014 | World Journal of Gastrointestinal Endoscopy2014，6，8： | 1 |
| 6 | User’s guide to viscosity solutions of second order partial differential equations显示文摘 | Crandall G M Hitoshi Ishii Pierre-Louis Lions | 1992 | Bull Amer Soc1992，27，1： | 1 |
| 7 | Characteristics of rat bone marrow cells differentiated into a liver cell lineage and dynamics of the transplanted cells in the injured liver显示文摘 | Kazuo Okumoto Takafumi Saito Hiroaki Haga Etsuko Hattori Rika Ishii Tetsuru Karasawa Akihiko Suzuki Keiko Misawa Mai Sanjo Jun-itsu Ito Kazuhiko Sugahara Koji Saito Hitoshi Togashi Sumio Kawata | 2006 | Journal of Gastroenterology2006，，1： | 1 |
| 8 | High Diagnostic Ability of Multiparametric Magnetic Resonance Imaging to Detect Anterior Prostate Cancer Missed by Transrectal 12-Core Biopsy显示文摘 | Yoshinobu Komai Noboru Numao Soichiro Yoshida Yoh Matsuoka Yasukazu Nakanishi Chikako Ishii Fumitaka Koga Kazutaka Saito Hitoshi Masuda Yasuhisa Fujii Satoru Kawakami Kazunori Kihara | 2013 | The Journal of Urology2013，，： | 1 |
| 9 | Effects of exercise on C-reactive protein, inflammatory cytokine and adipokine in patients with type 2 diabetes: A meta-analysis of randomized controlled trials显示文摘 | Yasuaki Hayashino Jeffrey L. Jackson Takumi Hirata Norio Fukumori Fumiaki Nakamura Shunichi Fukuhara Satoru Tsujii Hitoshi Ishii | 2013 | Metabolism2013，，： | 1 |
| 10 | Endoscopic submucosal dissection for laterally spreading tumours of the colorectum in 200 consecutive cases显示文摘 | Hitoshi Nishiyama Hajime Isomoto Naoyuki Yamaguchi Hiroyuki Ishii Eiichiro Fukuda Haruhisa Machida Takashi Nakamura Ken Ohnita Saburo Shikuwa Shigeru Kohno Kazuhiko Nakao | 2010 | Surgical Endoscopy2010，，： | 1 |
| 11 | User's Guide to Viscosity Solutions of Second-order Partial Differential Equations 显示文摘 | Micheal GCrandall Hitoshi Ishii Pierre Louis Lions | 1992 | Bulletin of the American Mathematical Society(new series)1992，27，1： | 1 |
| 12 | Endoscopic submucosal dissection for rectal carcinoid tumors显示文摘 | Naoyuki Yamaguchi Hajime Isomoto Hitoshi Nishiyama Eiichiro Fukuda Hiroyuki Ishii Takashi Nakamura Ken Ohnita Tomayoshi Hayashi Shigeru Kohno Kazuhiko Nakao Saburo Shikuwa | 2010 | Surgical Endoscopy2010，，3： | 1 |
| 13 | Initial Experience of Diffusion-weighted Magnetic Resonance Imaging to Assess Therapeutic Response to Induction Chemoradiotherapy Against Muscle-invasive Bladder Cancer显示文摘 | Soichiro Yoshida Fumitaka Koga Satoru Kawakami Chikako Ishii Hiroshi Tanaka Noboru Numao Yasuyuki Sakai Kazutaka Saito Hitoshi Masuda Yasuhisa Fujii Kazunori Kihara | 2010 | Urology2010，，2： | 1 |
| 14 | Genetic variations in humans associated with differences in the course of hepatitis C显示文摘 | Takafumi Saito Guijin Ji Haruhide Shinzawa Kazuo Okumoto Etsuko Hattori Tohru Adachi Tadashi Takeda Kazuhiko Sugahara Jun-itsu Ito Hisayoshi Watanabe Koji Saito Hitoshi Togashi Keisuke Ishii Tadashi Matsuura Kiyoshi Inageda Masaaki Muramatsu Sumio Kawata | 2004 | Biochemical and Biophysical Research Communications2004，，2： | 1 |
| 15 | Characteristics of rat bone marrow cells differentiated into a liver cell lineage and dynamics of the transplanted cells in the injured liver显示文摘 | Kazuo Okumoto Takafumi Saito Hiroaki Haga Etsuko Hattori Rika Ishii Tetsuru Karasawa Akihiko Suzuki Keiko Misawa Mai Sanjo Jun-itsu Ito Kazuhiko Sugahara Koji Saito Hitoshi Togashi Sumio Kawata | 2006 | Journal of Gastroenterology2006，，1： | 1 |
| 16 | 0.025-inch vs 0.035-inch guide wires for wire-guided cannulation during endoscopic retrograde cholangio pancreatography:A randomized study显示文摘AIM:To compare the clinical outcomes between 0.025-inch and 0.035-inch guide wires(GWs) when used in wire-guided cannulation(WGC).METHODS:A single center,randomized study was conducted between April 2011 and March 2013. This study was approved by the Medical Ethics Committee at our hospital. Informed,written consent was obtained from each patient prior to study enrollment. Three hundred and twenty-two patients with a na?ve papilla of Vater who underwent endoscopic retrograde cholangiopancreatography(ERCP) for the purpose of selective bile duct cannulation with WGC were enrolled in this study. Fifty-three patients were excluded based on the exclusion criteria,and 269 patients were randomly allocated to two groups by a computer and analyzed:the 0.025-inch GW group(n = 109) and the 0.035-inch GW group(n = 160). The primary endpoint was the success rate of selective bile duct cannulation with WGC. Secondary endpoints were the success rates of the pancreatic GW technique and precutting,selective bile duct cannulation time,ERCP procedure time,the rate of pancreatic duct stent placement,the final success rate of selective bile duct cannulation,andthe incidence of post-ERCP pancreatitis(PEP).RESULTS:The primary success rates of selective bile duct cannulation with WGC were 80.7%(88/109) and 86.3%(138/160) for the 0.025-inch and the 0.035-inch groups,respectively(P = 0.226). There were no statistically significant differences in the success rates of selective bile duct cannulation using the pancreatic duct GW technique(46.7% vs 52.4% for the 0.025-inch and 0.035-inch groups,respectively; P = 0.884) or in the success rates of selective bile duct cannulation using precutting(66.7% vs 63.6% for the 0.025-inch and 0.035-inch groups,respectively; P = 0.893). The final success rates for selective bile duct cannulation using these procedures were 92.7%(101/109) and 97.5%(156/160) for the 0.025-inch and 0.035-inch groups,respectively(P = 0.113). There were no significant differences in selective bile duct cannulation time(median ± interquartile range:3.7 ± 13.9 min vs 4.0 ± 11.2 min for the 0.025-inch and 0.035-inch groups,respectively; P = 0.851),ERCP procedure time(median ± interquartile range:32 ± 29 min vs 30 ± 25 min for the 0.025-inch and 0.035-inch groups,respectively; P = 0.184) or in the rate of pancreatic duct stent placement(14.7% vs 15.6% for the 0.025-inch and 0.035-inch groups,respectively; P = 0.832). The incidence of PEP was 2.8%(3/109) and 2.5%(4/160) for the 0.025-inch and 0.035-inch groups,respectively(P = 0.793).CONCLUSION:The thickness of the GW for WGC does not appear to affect either the success rate of selective bile duct cannulation or the incidence of PEP. | Katsuya Kitamura Akira Yamamiya Yu Ishii Yoshiki Sato Tomoyuki Iwata Tomohiro Nomoto Akitoshi Ikegami Hitoshi Yoshida | 2015 | World Journal of Gastroenterology2015，21，30： | 1 |
| 17 | Age-related changes of mitochondrial structure and function in Caenorhabditis elegans 显示文摘 | Kayo Yasuda Takamasa Ishii Hitoshi Suda | 2006 | Mech Ageing Dev2006，127，： | 1 |
| 18 | Reproducibility and validity of a satisfaction questionnaire on hypoglycemic agents: the oral hypoglyeemic agent questionnaire ( OHA - Q ) 显示文摘 | Ishii Hitoshi Oda Eisei | 2012 | Diabetology International2012，3，3： | 1 |
| 19 | Gastric duplication cyst: Evaluation by endoscopic ultrasonography and magnetic resonance imaging显示文摘 | Takashi Takahara Toshihiko Torigoe Hiromitsu Haga Hitoshi Yoshida Shinji Takeshima Shinji Sano Yoshifumi Ishii Takashi Furuya Eishu Nakamura Masahisa Ishikawa | 1996 | Journal of Gastroenterology1996，，3： | 1 |
| 20 | A Novel Avian Hypothalamic Peptide Inhibiting Gonadotropin Release显示文摘 | Kazuyoshi Tsutsui Etsuko Saigoh Kazuyoshi Ukena Hitoshi Teranishi Yuko Fujisawa Motoshi Kikuchi Susumu Ishii Peter J. Sharp | 2000 | Biochemical and Biophysical Research Communications2000，，2： | 1 |
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