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| 1 | Biliary tract schwannoma:A rare cause of obstructive jaundice in a young patient显示文摘Schwannoma is a tumor derived from Schwann cells which usually arises in the upper extremities, trunk, head and neck, retroperitoneum, mediastinum, pelvis, and peritoneum. However, it can arise in the gastro-intestinal tract, including biliary tract. We present a 24-year-old male patient with obstructive jaundice, whose investigation with computed tomography abdomen showed focal wall thickening in the common hepatic duct, difficult to differentiate with hilar adenocarcinoma. He was diagnosed intraoperatively schwannoma of common bile duct and treated with local resection. The patient recovered well without signs of recurrence of the lesion after 12 mo. We also reviewed the common bile duct schwannoma related in the literature and evaluated the difficulty in pre and intraoperative differential diagnosis with adenocarcinoma hilar. Resection is the treatment of choice for such cases and the tumordid not recur in any of the resected cases. | Gilton Marques Fonseca André Luis Montagnini Manoel de Souza Rocha Rosely Antunes Patzina Mário Vinícius Angelete Alvarez Bernardes Ivan Cecconello José Jukemura | 2012 | World Journal of Gastroenterology2012，18，37： | 10 |
| 2 | Al-Cu-Zr和Al-Cu-Zr-Ti-V合金中Al_3Zr析出相的析出行为(英文)显示文摘利用透射电子显微技术研究Al-Cu-Zr和Al-Cu-Zr-Ti-V合金中Al3Zr的沉淀析出行为。亚稳态的Al3Zr沉淀相在枝晶中心均匀形核并获得均匀分布。然而,在枝晶边缘区域的析出复杂,观察到由许多球形Al3Zr析出颗粒组成的螺旋状和条状的形貌。条状的沉淀团簇沿100铝方向优先排列,这可能与Al2Cu的亚稳态θ′和稳态θ析出相相关。添加铜有利于Al3Zr沉淀相从L12→D023的结构转变。 | 贾志宏 Jean-Philippe COUZINIé Nadia CHERDOUDI Ivan GUILLOT LarsRNBERG Petter SHOLT Stig BRUSETHAUG Bruno BARLAS5 Denis MASSINON | 2012 | Transactions of Nonferrous Metals Society of China2012，22，8： | 9 |
| 3 | Determinants of percutaneous coronary intervention success in repeat chronic total occlusion procedures following an initial failed attempt显示文摘AIM To investigate the rates and determinants of success of repeat percutaneous coronary intervention(PCI) following an initial failed attempt at recanalising the chronic total occlusions(CTO) percutaneously.METHODS In 445 consecutive first attempt CTO-PCI procedures in our institution,procedural failure occurred in 149(33.5%). Sixty-four re-PCI procedures were performed in 58 patients(39%) all had a single CTO. Procedural and outcome data in the re-PCI population was entered into the institutional database. A retrospective analysis of clinical,angiographic and procedural data was performed. RESULTS Procedural success was achieved in 41(64%) procedures. Univariate analysis of clinical and angiographic characteristics showed that re-PCI success was associated with intravascular ultrasound(IVUS) guidance(19.5% vs 0%,P = 0.042),while failure was associated with severecalcification(30.4% vs 9.7%,P = 0.047) and a JCTO score > 3(56.5% vs 17.1% P = 0.003). Following multiple regression analysis the degree of lesion complexity(J-CTO score > 3),IVUS use,involvement of an experienced CTO operator and LAD CTO location were significant predictors of successful re-PCI. Overall the complication rate was low,with the only MACCE two periprocedural MI's neither of which required intervention. CONCLUSION Re-PCI substantially increases the overall success rate of CTO revascularization. Predictors of re-PCI success included the use of IVUS,the involvement of an experienced CTO operator in the repeat attempt and the location of the CTO. | Cecilia Cuevas Nicola Ryan Alicia Quirós Juan Gustavo Del Angel Nieves Gonzalo Pablo Salinas Pilar Jiménez-Quevedo Luis Nombela-Franco Ivan Nunez-Gil Antonio Fernandez-Ortiz Carlos Macaya Javier Escaned | 2017 | World Journal of Cardiology2017，9，4： | 5 |
| 4 | Peripheral and mesenteric serum levels of CEA and cytokeratins,staging and histopathological variables in colorectal adenocarcinoma显示文摘瞄准:为了评估在外设和 mes 伤寒浆液之间存在的差别,与颜色在病人 carcinoembryonic 铺平抗原(CEA ) 和 cytokeratins 表面的腺癌。方法:有颜色的 138 个病人表面的腺癌在在 1993 年 12 月和 2000 年 3 月之间的医院 Sao Paulo (UNIFESP-EPM 的外科的肠胃病学的纪律) 经历了外科的人,回顾地被分析。CEA 和 cytokeratin (TPA-M ) 之间的差别在外部血(P) 并且在 mes 伤寒血(M) 的层次被学习。协会在外设和 mes 伤寒层次和阶段和组织病理学说的变量(细胞分化,宏观的外观,肿瘤尺寸和淋巴、静脉的侵略的存在的度) 之间被调查。结果:差别在标记层次的数字价值被观察:CEA (M)(39.10 mg/L +/- 121.19 mg/L ) 对 CEA (P)(38.5 mg/L +/- 122.55 mg/L ) , P <
0.05;TPA-M (M)(325.06 U/L +/- 527.29 U/L ) 对 TPA-M (P)(279.48 U/L +/- 455.81 U/L ) , P <
0.01。mes 伤寒 CEA 层次在更先进的肿瘤是更高的(P <
0.01 ) ,在生长损害(34.44 mg/L +/- 93.07 mg/L )(P <
0.01 ) 并且与静脉的侵略(48.41 mg/L +/- 129.86 mg/L )(P <
0.05 ) 。外部 CEA 与更先进的阶段是更高的(P <
0.01 ) 并且在有静脉的侵略的损害(53.23 mg/L +/- 158.57 mg/L )(P <
0.05 ) 。病人表明了有更多的 TPA-M 层次预付肿瘤的伤寒、外部的增加的 mes (P <
0.01 并且 P <
0.01 ) 并且在非溃烂的损害[530.45 U/L +/- 997.46 U/L (P <
0.05 ) 并且 457.95 U/L +/- 811.36 U/L (P <
0.01 )] 。结论:肿瘤标记 CEA 和 cytokeratins 的 mes 伤寒层次比在这些的外部层次渲染表面的腺癌病人高。这些生物学的肿瘤标记的高水平与癌的传播的一个先进状态被联系。 | Ivan Gregório Ivankovics Luis César Fernandes Sarhan Sydeney Saad Delcio Matos | 2008 | World Journal of Gastroenterology2008，14，43： | 4 |
| 5 | Chromosome-scale scaffolding of the black raspberry (Rubus occidentalis L.) genome based on chromatin interaction data显示文摘Black raspberry(Rubus occidentalis L.)is a niche fruit crop valued for its flavor and potential health benefits.The improvement of fruit and cane characteristics via molecular breeding technologies has been hindered by the lack of a high-quality reference genome.The recently released draft genome for black raspberry(ORUS 4115-3)lacks assembly of scaffolds to chromosome scale.We used high-throughput chromatin conformation capture(Hi-C)and Proximity-Guided Assembly(PGA)to cluster and order 9650 out of 11,936 contigs of this draft genome assembly into seven pseudo-chromosomes.The seven pseudo-chromosomes cover~97.2%of the total contig length(~223.8 Mb).Locating existing genetic markers on the physical map resolved multiple discrepancies in marker order on the genetic map.Centromeric regions were inferred from recombination frequencies of genetic markers,alignment of 303 bp centromeric sequence with the PGA,and heat map showing the physical contact matrix over the entire genome.We demonstrate a high degree of synteny between each of the seven chromosomes of black raspberry and a high-quality reference genome for strawberry(Fragaria vesca L.)assembled using only PacBio long-read sequences.We conclude that PGA is a cost-effective and rapid method of generating chromosome-scale assemblies from Illumina short-read sequencing data. | Rubina Jibran Helge Dzierzon Nahla Bassil Jill M.Bushakra Patrick P.Edger Shawn Sullivan Chad E.Finn Michael Dossett Kelly J.Vining Robert VanBuren Todd C.Mockler Ivan Liachko Kevin M.Davies Toshi M.Foster David Chagné | 2018 | Horticulture Research2018，5，1： | 4 |
| 6 | Astrocytes protect dopaminergic neurons against aminochrome neurotoxicity显示文摘Astrocytes protect neurons by modulating neuronal function and survival.Astrocytes support neurons in several ways.They provide energy through the astrocyte-neuron lactate shuttle,protect neurons from excitotoxicity,and internalize neuronal lipid droplets to degrade fatty acids for neuronal metabolic and synaptic support,as well as by their high capacity for glutamate uptake and the conversion of glutamate to glutamine.A recent reported astrocyte system for protection of dopamine neurons against the neurotoxic products of dopamine,such as aminochrome and other o-quinones,were generated under neuromelanin synthesis by oxidizing dopamine catechol structure.Astrocytes secrete glutathione transferase M2-2 through exosomes that transport this enzyme into dopaminergic neurons to protect these neurons against aminochrome neurotoxicity.The role of this new astrocyte protective mechanism in Parkinson´s disease is discussed. | Juan Segura-Aguilar Bengt Mannervik JoséInzunza Mukesh Varshney Ivan Nalvarte Patricia Muñoz | 2022 | Neural Regeneration Research2022，17，9： | 3 |
| 7 | The challenges on operating a zero net energy building facing global warming conditions显示文摘This study proposes a methodology to evaluate the energy performance of existing Zero Energy Buildings and to prospect retrofit strategies in a Savannah climate,concerning the A2 scenario of emissions from the Fourth Report of the Intergovernmental Panel on Climate Change.The selected building to study is recognized for its high energy performance,named Centro SEBRAE de Sustentabilidade(CSS).Two efficient measures were considered:(i)improvement in the air conditioning system coefficient of performance(COP)and(ii)in the energy efficiency of the photovoltaic plates of generation on-site.The methodology is grounded in the potential bioclimatic concept and the employed steps applied were:preparation of climate archives in the 2020,2050 and 2080 time-slices;calibration of the computational model;evaluation of the retrofit strategies on its energy consumption efficiency through computer simulation.Considering the CSS has already attended mostly the bioclimatic strategies for the local climate and has high efficiency measures in its systems,the retrofit focused the air conditioning and PV system.The isolated retrofit of the air conditioning system was unable to guarantees the NZEB condition despite providing an adequate level of energy efficiency until 2080.The retrofit of the PV system was the only one that provides the NZEB condition for climate change scenarios.The contribution of this paper is to provide a guide to be used in NZEBs,with measures of optimization that provide high potential bioclimatic face to the local where it is built,making it possible to maintain this condition in scenarios of global warming. | Alberto Hernandez Neto Luciane Cleonice Durante Ivan Julio Apolonio Callejas Emeli Lalesca Aparecida da Guarda JoséVinnicius Ranieri Moreira | 2022 | Building Simulation2022，15，3： | 2 |
| 8 | Modeling and identification of fertility maps using artificial neural networks显示文摘 | José A Ulson Ivan N Silva Sérgio H Benez | 2000 | IEEE2000，，： | 1 |
| 9 | Updated Clinical Classification of Pulmonary Hypertension显示文摘 | Gérald Simonneau Ivan M. Robbins Maurice Beghetti Richard N. Channick Marion Delcroix Christopher P. Denton C. Gregory Elliott Sean P. Gaine Mark T. Gladwin Zhi-Cheng Jing Michael J. Krowka David Langleben Norifumi Nakanishi Rogério Souza | 2009 | Journal of the American College of Cardiology2009，，1： | 1 |
| 10 | Ecosystem CO<sub>2</sub> fluxes of arbuscular and ectomycorrhizal dominated vegetation types are differentially influenced by precipitation and temperature显示文摘 | RodrigoVargas Dennis D.Baldocchi José I.Querejeta Peter S.Curtis Niles J.Hasselquist Ivan A.Janssens Michael F.Allen LeonardoMontagnani | 2009 | New Phytologist2009，，1： | 1 |
| 11 | Controlling persistent organic pollutants–what next? 1 Correspondence to: Nicole G Weavers, ETAF, European Training and Assessment Foundation, PO Box 182, 6700 AD, Wageningen, The Netherlands. Tel.: +31-317-484924; Fax: +31-317-484941 1显示文摘 | Harry W. Vallack Dick J. Bakker Ingvar Brandt Eva Brostr?m-Lundén Abraham Brouwer Keith R. Bull Clair Gough Ramon Guardans Ivan Holoubek Bo Jansson Rainer Koch Johan Kuylenstierna André Lecloux Donald Mackay Patrick McCutcheon Paolo Mocarelli Rob D.F. Taa | 1998 | Environmental Toxicology and Pharmacology1998，，3： | 1 |
| 12 | Primary Results of Laparoscopic Mini-Gastric Bypass in a French Obesity-Surgery Specialized University Hospital显示文摘 | Ghassan Chakhtoura Franck Zinzindohoué Yassine Ghanem Ivan Ruseykin Jean-Christophe Dutranoy Jean-Marc Chevallier | 2008 | Obesity Surgery2008，，9： | 1 |
| 13 | Glypican-3 regulates migration, adhesion and actin cytoskeleton organization in mammary tumor cells through Wnt signaling modulation显示文摘 | Ivan Stigliano Lydia Puricelli Jorge Filmus Mari Cleide Sogayar Elisa Bal de Kier Joffé María Giselle Peters | 2009 | Breast Cancer Research and Treatment2009，，2： | 1 |
| 14 | Endoscopic Sphincterotomy Before Deployment of Covered Metal Stent is Associated With Greater Complication Rate: A Prospective Randomized Control Trial显示文摘 | Everson L. A. Artifon Paulo Sakai Shinichi Ishioka Sérgio B. Marques André S. Lino José E. M. Cunha José Jukemura Ivan Cecconello Flair J. Carrilho Eduardo Opitz Atul Kumar | 2008 | Journal of Clinical Gastroenterology2008，，7： | 1 |
| 15 | BMI1 , The polycomb‐group gene, is recurrently targeted by genomic rearrangements in progressive B‐cell leukemia/lymphoma显示文摘 | Leila Rouhigharabaei Julio Finalet Ferreiro Natalie Put Lucienne Michaux Thomas Tousseyn Christine Lefebvre Anne Gardiner Wim Kelver Hilde Demuynck Johan Verschuere Ivan Théate Carmen Vicente Peter Vandenberghe Jan Cools Iwona Wlodarska | 2013 | Genes Chromosomes Cancer2013，，10： | 1 |
| 16 | Molecular profiling of early stage liver fibrosis in patients with chronic hepatitis C virus infection显示文摘 | Ivan Bièche Tarik Asselah Ingrid Laurendeau Dominique Vidaud Claude Degot Valérie Paradis Pierre Bedossa Dominique-Charles Valla Patrick Marcellin Michel Vidaud | 2004 | Virology2004，，1： | 1 |
| 17 | Neutrophil Gelatinase-Associated Lipocalin Is a Novel Mineralocorticoid Target in the Cardiovascular System显示文摘 | Celine Latouche Soumaya El Moghrabi Smail Messaoudi Aurélie Nguyen Dinh Cat Ivan Hernandez-Diaz Diego Alvarez de la Rosa Claudine Perret Natalia López Andrés Patrick Rossignol Faiez Zannad Nicolette Farman Frederic Jaisser | 2012 | Hypertension2012，，： | 1 |
| 18 | The prognostic value of CD147/EMMPRIN is associated with monocarboxylate transporter 1 co-expression in gastric cancer显示文摘 | Céline Pinheiro Adhemar Longatto-Filho Kleber Sim?es Carlos Eduardo Jacob Cláudio José Caldas Bresciani Bruno Zilberstein Ivan Cecconello Venancio Avancini Ferreira Alves Fernando Schmitt Fátima Baltazar | 2009 | European Journal of Cancer2009，，13： | 1 |
| 19 | Development of multiresidue DLLME and QuEChERS based LC–MS/MS method for determination of selected neonicotinoid insecticides in honey liqueur显示文摘 | Pavle Jovanov Valéria Guzsvány Mladen Franko Sanja Lazi? Marijana Saka? Ivan Milovanovi? Nata?a Nedeljkovi? | 2014 | Food Research International2014，，： | 1 |
| 20 | Limited Acquisition of Chromosomal Aberrations in Human Adult Mesenchymal Stromal Cells显示文摘 | Luc Sensebé Karin Tarte Jacques Galipeau Mauro Krampera Ivan Martin Donald G. Phinney Yufang Shi | 2012 | Cell Stem Cell2012，，1： | 1 |
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