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| 1 | Overlapping expression of microRNAs in human embryonic colon and colorectal cancer显示文摘MicroRNAs (miRNAs ) 为调整房间区别并且维持干细胞的 pluripotent 状态是必要的。尽管特定的 miRNAs 的 dysregulation 与癌症的某些类型被联系了,到日期,没有证据连接了 miRNA 表示在胚胎并且肿瘤纸巾。我们在人的胚胎的结肠组织,并且在 colorectal 癌症估计了成熟 miRNAs 的表示并且配对正常结肠组织。重叠 miRNA 表示在胚胎的结肠的 mucosa 和 colorectal 癌症之间被检测。我们发现了 miR-17-92 聚类,调整在两个盒子中的房间增长并且它的目标, E2F1,在人的冒号开发和结肠的 carcinogenesis 展出表示的一个类似的模式。在 situ,杂交在地窟祖先分隔空间证实了 miR-17-5p 的表示的高水平。我们断定 miRNA 小径在胚胎的开发和结肠的上皮的肿瘤的转变起一个主要作用。 | Mariano Monzo Alfons Navarro Eva Bandres Rosa Artells Isabel Moreno Bemat Gel Rafael Ibeas Jose Moreno Francisco Martinez Tania Diaz Antonio Martinez Olga Balague Jesus Garcia-Foncillas | 2008 | Cell Research2008，18，8： | 32 |
| 2 | Synthesis of γ-Al203 anopowders by freeze-drying显示文摘 | Carolina Tallon Rodrigo Moreno M Isabel Nieto | 2006 | Materials Research Bulletin2006，41，： | 1 |
| 3 | Determination of microcystins in natural blooms and cyanobaeterial strain culture sbymatrix solid - phase dispersionand liquid chromatography mass spectrometry显示文摘 | Ana Camea'n Isabel M Moreno Marl'a J RuizYolanda Pico' | 2004 | Anal Bioanal Chem2004，380，： | 1 |
| 4 | Gluten immunogenic peptide excretion detects dietary transgressions in treated celiac disease patients显示文摘BACKGROUND Life-long removal of gluten from the diet is currently the only way to manage celiac disease(CeD). Until now, no objective test has proven useful to objectively detect ingested gluten in clinical practice. Recently, tests that determine consumption of gluten by assessing excretion of gluten immunogenic peptides(GIP) in stool and urine have been developed. Their utility, in comparison with conventional dietary and analytical follow-up strategies, has not been fully established.AIM To assess the performance of enzyme-linked immunosorbent assay(ELISA) and point-of-care tests(PoCTs) for GIP excretion in CeD patients on gluten-free diet(GFD).METHODS We conducted an observational, prospective, cross-sectional study in patients following a GFD for at least two years. Using the Gastrointestinal Symptom Rating Scale questionnaire, patients were classified at enrollment as asymptomatic or symptomatic. Gluten consumption was assessed twice by 3-d dietary recall and GIP excretion(by ELISA in stool and PoCTs(commercial kits for stool and urine) in two consecutive samples. These samples and dietary reports were obtained 10 day apart one from the other. Patients were encouraged to follow their usual GFD during the study period.RESULTS Forty-four patients were enrolled, of which 19(43.2%) were symptomatic despite being on a GFD. Overall, 83 sets of stool and/or urine samples were collected.Eleven out of 44 patients(25.0%) had at least one positive GIP test. The occurrence of at least one positive test was 32% in asymptomatic patients compared with 15.8% in symptomatic patients. GIP was concordant with dietary reports in 65.9% of cases(Cohen′s kappa: 0.317). PoCT detected dietary indiscretions. Both ELISA and PoCT in stool were concordant(concomitantly positive or negative) in 67 out of 74(90.5%) samples. Excretion of GIP was detected in 7(8.4%) stool and/or urine samples from patients considered to be strictly compliant with the GFD by dietary reports.CONCLUSION GIP detects dietary transgressions in patients on long-term GFD, irrespective of the presence of symptoms. PoCT for GIP detection constitutes a simple homebased method for self-assessment of dietary indiscretions. | Ana Florencia Costa Emilia Sugai María de la Paz Temprano Sonia Isabel Niveloni Horacio Vázquez María Laura Moreno M.Remedios Domínguez-Flores Alba Mu?oz-Suano Edgardo Smecuol Juan Pablo Stefanolo Andrea F González Angel Cebolla-Ramirez Eduardo Mauri?o Elena F Verdú Julio César Bai | 2019 | World Journal of Gastroenterology2019，25，11： | 1 |
| 5 | The food contaminant deoxynivalenol, decreases intestinal barrier permeability and reduces claudin expression显示文摘 | Philippe Pinton Jean-Philippe Nougayrède Juan-Carlos Del Rio Carolina Moreno Daniela E. Marin Laurent Ferrier Ana-Paula Bracarense Martine Kolf-Clauw Isabelle P. Oswald | 2009 | Toxicology and Applied Pharmacology2009，，1： | 1 |
| 6 | Sustained virological response with telaprevir in 1078 patients with advanced hepatitis C: The international telaprevir access program显示文摘 | Massimo Colombo Simone Strasser Christophe Moreno Paulo Abrao Ferreira Petr Urbanek Inmaculada Fernández Djamal Abdurakmonov Adrian Streinu-Cercel Anke Verheyen Wafae Iraqi Ralph DeMasi Andrew Hill Isabelle Lonjon-Domanec Heiner Wedemeyer | 2014 | Journal of Hepatology2014，，5： | 1 |
| 7 | Alumina bodies with near-to-theoretical density by aqueous gelcasting using concentrated agarose solutions显示文摘 | Isabel Santaeruz Ma Isabel Nieto Rodrigo Moreno | 2005 | Ceramics International2005，31，： | 1 |
| 8 | Differential MIR-21 Expression in Plasma From Mesenteric Versus Peripheral Veins: An Observational Study of Disease-free Survival in Surgically Resected Colon Cancer Patients显示文摘 | Mariano Monzo Francisco Martínez-Rodenas Isabel Moreno Alfons Navarro Sandra Santasusagna Ismael Macias Carmen Mu?oz Rut Tejero Raquel Hernández | 2015 | Medicine2015，，1： | 1 |
| 9 | Endoscopic Removal of Large Sessile Colorectal Adenomas: Is It Safe and Effective?显示文摘 | Jaume Boix Vicente Lorenzo-Zú?iga Vicente Moreno de Vega Fidel E. A?a?os Eugeni Domènech Isabel Ojanguren Miquel A. Gassull | 2007 | Digestive Diseases and Sciences2007，，3： | 1 |
| 10 | N -glycan based biomarker distinguishing non-alcoholic steatohepatitis from steatosis independently of fibrosis显示文摘 | Bram Blomme Sven Francque Eric Trépo Louis Libbrecht Dieter Vanderschaeghe An Verrijken Piet Pattyn Yves Van Nieuwenhove Dirk Van De Putte Anja Geerts Isabelle Colle Joris Delanghe Christophe Moreno Luc Van Gaal Nico Callewaert Hans Van Vlierberghe | 2011 | Digestive and Liver Disease2011，，4： | 1 |
| 11 | Enteral nutrition with or without N -acetylcysteine in the treatment of severe acute alcoholic hepatitis: A randomized multicenter controlled trial显示文摘 | Christophe Moreno Philippe Langlet Axel Hittelet Luc Lasser Delphine Degré Sylvie Evrard Isabelle Colle Arnaud Lemmers Jacques Devière Olivier Le Moine | 2010 | Journal of Hepatology2010，，6： | 1 |
| 12 | Hepatitis B virus and hepatitis C virus infections in Belgium: similarities and differences in epidemics and initial management显示文摘 | Bénédicte De Vroey Christophe Moreno Wim Laleman Marc van Gossum Isabelle Colle Chantal de Galocsy Philippe Langlet Geert Robaeys Hans Orlent Peter Michielsen Jean Delwaide Hendrik Reynaert Fran?ois D’Heygere Dirk Sprengers Stefan Bourgeois Collins Assene | 2013 | European Journal of Gastroenterology & Hepatology2013，，5： | 1 |
| 13 | Low field nuclear magnetic resonance (LF-NMR) relaxometry in hake ( Merluccius merluccius , L.) muscle after different freezing and storage conditions显示文摘 | Isabel Sánchez-Alonso Pilar Moreno Mercedes Careche | 2013 | Food Chemistry2013，，： | 1 |
| 14 | Burned Area Mapping in the North American Boreal Forest Using Terra-MODIS LTDR (2001 - 2011 ) : A Comparison with the MCIM5AI, MCD64A1 and BA GEO-LAND-2 Products显示文摘 | JoseAndres Moreno Ruiz Jos6Rafael Garcia Lazaro Isabel del aguila Canol and Pedro Hernandez Leal | 2014 | Remote Sensing2014，6，： | 1 |
| 15 | Toxic cyanobacterial cells containing microcystins induce oxidative stress in exposed tilapia fish ( Oreochromis sp.) under laboratory conditions显示文摘 | ángeles Jos Silvia Pichardo Ana I. Prieto Guillermo Repetto Carmen M. Vázquez Isabel Moreno Ana M. Cameán | 2005 | Aquatic Toxicology2005，，3： | 1 |
| 16 | Oxidized organic molecules in the tropical free troposphere over Amazonia显示文摘New particle formation(NPF) in the tropical free troposphere(FT) is a globally important source of cloud condensation nuclei, affecting cloud properties and climate. Oxidized organic molecules(OOMs)produced from biogenic volatile organic compounds are believed to contribute to aerosol formation in the tropical FT, but without direct chemical observations. We performed in situ molecular-level OOMs measurements at the Bolivian station Chacaltaya at 5240 m above sea level, on the western edge of Amazonia. For the first time, we demonstrate the presence of OOMs, mainly with 4–5 carbon atoms, in both gas-phase and particle-phase(in terms of mass contribution) measurements in tropical FT air from Amazonia. These observations, combined with air mass history analyses, indicate that the observed OOMs are linked to isoprene emitted from the rainforests hundreds of kilometers away. Based on particle-phase measurements, we find that these compounds can contribute to NPF, at least the growth of newly formed nanoparticles, in the tropical FT on a continental scale. Thus, our study is a fundamental and significant step in understanding the aerosol formation process in the tropical FT. | Qiaozhi Zha Diego Aliaga Radovan Krejci Victoria ASinclair Cheng Wu Giancarlo Ciarelli Wiebke Scholz Liine Heikkinen Eva Partoll Yvette Gramlich Wei Huang Markus Leiminger Joonas Enroth Otso Perakyla Runlong Cai Xuemeng Chen Alkuin Maximilian Koenig Fernando Velarde Isabel Moreno Tuukka Petaja Paulo Artaxo Paolo Laj Armin Hansel Samara Carbone Markku Kulmala Marcos Andrade Douglas Worsnop Claudia Mohr Federico Bianchi | 2024 | National Science Review2024，11，1： | 0 |
| 17 | Cantharellus(Cantharellales,Basidiomycota)revisited in Europe through a multigene phylogeny显示文摘Resolving species delimitation issues of European Cantharellus is crucial to correctly name chanterelles around the globe.Thirty names referring to Cantharellus s.str.have been described in Europe,some of which are used in other continents.Based on combined analyses of ITS2,LSU,RPB2 and TEF-1,merely eight species are here recognized in Europe applying the genealogical concordance phylogenetic species recognition criteria,one of which,C.roseofagetorum,is described as new.Morphological characters used in species delimitation are mapped and their variability evaluated.The colour of the hymenophore in young specimens is found to be a rather constant morphological character of taxonomic use.European species of Cantharellus are morphologically distinguished by unique combinations of characters,such as the presence of a pink pileal coating,pileus and hymenophore colour when young,and in some cases,the mean spore length and ecology.Eighteen type specimens from Europe are sequenced.Based on revised species concepts sixteen novel taxonomic synonyms are here proposed for European chanterelles:C.alborufescens(=C.henrici,C.ilicis,C.lilacinopruinatus),C.amethysteus(=C.cibarius subsp.squamulosus,C.cibarius var.umbrinus,C.rufipes),C.cibarius(=C.cibarius var.atlanticus,C.parviluteus),C.ferruginascens(=C.cibarius var.flavipes),C.friesii(=C.ignescens),C.pallens(=C.cibarius var.albidus,C.cibarius var.bicolor,C.subpruinosus),and C.romagnesianus(=C.pseudominimus,C.lourizanianus,C.romagnesianus var.parvisporus).The type of Cantharellus,C.cibarius,is epitypified.Descriptions,colour illustrations and a key to all European species are provided. | Ibai Olariaga Gabriel Moreno Jose Luis Manjon Isabel Salcedo Valerie Hofstetter Diego Rodrıguez Bart Buyck | 2017 | Fungal Diversity2017，，2： | 0 |
| 18 | Upper gastrointestinal endoscopic findings in celiac disease at diagnosis:A multicenter international retrospective study显示文摘BACKGROUND Gastroduodenal endoscopy and biopsy following positive specific serology is considered the gold standard to diagnose celiac disease(CeD)in adults.Whether upper endoscopy helps detect comorbid conditions is unknown.AIM To investigate the prevalence of non-celiac endoscopic findings in patients in whom endoscopy was performed to confirm CeD diagnosis.METHODS This is an observational,descriptive,multicenter,retrospective study that reports endoscopic findings obtained in adult patients enrolled in local registries from four tertiary centers.We collected data reported on first endoscopy,indicated for investigation of CeD.Diagnosis of CeD was performed by histology(≥Marsh 2type mucosal damage)and specific serology.Two European and one North American center included biopsy-confirmed CeD following positive serology.A fourth center(South America)included symptomatic patients undergoing endoscopy,irrespective of CeD serology.The latter cohort included a non-CeD control group.RESULTS A total of 1328 patients(80%female;35 years median age)were enrolled,of whom 95.6%had positive specific serology.In 135 patients,endoscopy revealed 163 abnormalities unrelated to CeD(prevalence:10.1%).Erosive reflux esophagitis(6.4%),gastric erosions(2.0%),and suspicion of esophageal metaplasia(1.2%)were the most common findings.Biopsy-confirmed Barrett’s esophagus was infrequent(0.2%).No endoscopic cancer was detected.Older patients(≥51 years of age)had a higher prevalence of endoscopic findings than those≤50(P<0.01).Within the South American cohort,CeD was associated with a lower rate(8.2%)of comorbid endoscopic findings compared with controls(29.1%;P<0.001).In the adjusted multivariate analysis of this cohort,having CeD was associated with a 72%reduction in the risk of any endoscopic abnormality(P<0.0001),and having alarm symptoms was associated with a 37%reduction in the risk of finding at least one endoscopic lesion(P<0.02).CONCLUSION In this large multicenter study,young adults with positive CeD serology had few comorbid endoscopic findings.Although patients over 51 years had a high prevalence of non-CeD gastroduodenal mucosal damage,no malignancy or premalignant lesions were found. | Juan Pablo Stefanolo Fabiana Zingone Carolina Gizzi Ilaria Marsilio María Luján Espinet Edgardo GustavoSmecuol Mark Khaouli María Laura Moreno María I Pinto-Sánchez Sonia Isabel Niveloni Elena F Verdú Carolina Ciacci Julio César Bai | 2022 | World Journal of Gastroenterology2022，28，43： | 0 |
| 19 | Colloidal and rheological characterization of SWCNT in biological media显示文摘Wereport on the colloidal and rheological characterization of suspensions of commercial single-walled carbon nanotubes(SWCNT)and oxidized single walled carbon nanotubes(SWCNT-oxi24h),in water and fetal bovine serum(FBS).The effects of two surfactants,dodecyl-benzene sodium sulfonate(SBDS)and sodium dodecyl sulfate(SDS)at different concentrations(0.5-2.0%)on the zeta potential and the rheology of the suspensions is also investigated.SWCNT suspensions were characterized by Transmission Electron Microscopy(TEM)and Atomic Force Microscopy(AFM).The colloidal stability was determined by measurements of zeta potential in the physiological pH range 6.0 | Arisbel Cerpa Isabel Lado Oriella Quiroga Rodrigo Moreno Rosario García Sebastián Cerdán Nehal I.Abu-Lail | 2019 | International Journal of Smart and Nano Materials2019，10，4： | 0 |
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