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| 1 | 地下水铀污染的原位微生物还原与固定:在美国能源部田纳西橡树岭放射物污染现场的试验显示文摘总结了美国斯坦福大学和橡树岭国家实验室等在美国能源部田纳西州橡树岭综合试验基地进行的铀污染原位微生物修复阶段性试验结果.本试验利用微生物以乙醇为电子供体还原地下水和沉积物中的六价铀为不溶解的四价铀,使之原位固定化.随后通过加入溶解氧和硝酸盐来试验微生物还原后的地下水层中还原固定态铀的稳定性.通过预处理和长期间隔注入乙醇溶液,地下水中铀浓度从40~60mg·L-1降至0.03mg·L-1以下,达到了美国环保署饮用水的标准.还原的四价铀主要以U(Ⅳ)-Fe复合物的形态存在.结果表明,固定化后的四价铀只有在厌氧条件下才是稳定的,溶解氧和硝酸盐侵入地下水层后会使固定化的四价铀重新氧化为溶解态的六价铀.在试验过程中,采用多种分子生物学方法检测了微生物种群的变化和与铀氧化还原反应有关的功能微生物.本研究表明,在维持试验系统无氧和无硝酸盐的条件下,通过添加乙醇为电子供体可有效地促进地下水中土著功能微生物的活性,从而实现铀的原位还原固定与稳定. | 吴唯民 Jack Carley David Watson 顾宝华 Scott Brooks Shelly D.Kelly Kenneth Kemner Joy D.van Nostrand 吴力游 许玫英 周集中 罗剑 Erick Cardenas 黄家琪 Matthew W.Fields Terence L.Marsh James M.Tiedje Stefan J.Green Joel E.Kostka Peter K.Kitanidis Philip M.Jardme CraigS.Criddle | 2011 | 环境科学学报2011，31，3： | 28 |
| 2 | 重症监护环境下心搏骤停患者的复苏后管理:循证指南依从性的回顾性分析显示文摘背景:循证的复苏后护理与患者出院后的生存及功能状态之间有明确的关系。澳大利亚复苏委员会(ARC)推荐采用程序化的护理,以提高患者心搏骤停后的存活机会。卫生服务机构有义务确保程序化的复苏后护理是及时的和循证的。目的 :本研究的目的是,对于院外或在急诊科发生心搏骤停经复苏后存活的患者,从急诊科转入重症监护室后,在患者自主循环恢复的首个24小时内,检查患者的复苏后护理遵循最佳操作指南的情况。方法:在澳大利亚墨尔本的两家医疗机构,对满足心搏骤停后存活标准的患者的病历进行回顾性分析。考察的指标为:原发性心搏骤停特征、氧合和通气管理、心血管护理、神经系统护理和患者预后。结果 :本研究有4项主要发现:(i)在首个24小时内的复苏后管理中,吸入气中的氧浓度分数(FIO2)为100%以及高氧血症常见;(ii)心脏护理有差异,及时给予12导联心电图监测,大部分患者的收缩压(SBP)高于100 mm Hg,但转入心导管实验室的时间延迟;(iii)神经护理不足,包括高血糖发生率高,以及高达50%的患者未提供低温治疗;(iv)患者入院后24小时内的院内病死率与复苏后护理的特定因素有关。结论 :有必要设定贯穿患者就医全过程的循证的,适合特定环境的指南,来指导复苏后护理。在实践中依赖国家级指南不一定能使其转化为健康机构内的循证实践。因此,迫切需要具体实施措施以确保指南的有效实施。 | A.Milonas A.Hutchinson D.Charlesworth A.Doric J.Green J.Considine | 2017 | 中国护理管理2017，17，12： | 4 |
| 3 | Land-walking vs.water-walking interventions in older adults:Effects on aerobic fitness显示文摘Background:Low cardiorespiratory fitness is an independent predictor of all-cause and cardiovascular mortality,and interventions that increase fitness reduce risk.Water-walking decreases musculoskeletal impact and risk of falls in older individuals,but it is unclear whether water-walking improves aerobic fitness in the same way as weight-dependent land-walking.This randomized controlled trial involved 3 intervention groups—a no-exercise control group(CG),a land-walking(LW)group,and a water-walking(WW)group—to investigate the comparative impacts of LWandWWto CG on fitness.Methods:Both exercise groups attended individually tailored,center-based,intensity-matched 3×weekly sessions for 24 weeks,which progressed to 150 min of exercise per week.This was followed by a 24-week no-intervention period.Maximal graded exercise tests were performed on a treadmill at Weeks 0,24,and 48.Results:Maximal oxygen uptake increased from Week 0 to Week 24 in both exercise groups(0.57±0.62 mL/kg/min,0.03±0.04 L/min for LW;0.93±0.75 mL/kg/min,0.06±0.06 L/min for WW,mean±SE)compared to the CG(-1.75±0.78 mL/kg/min,-0.16±0.05 L/min)(group×time,p<0.05).Time to exhaustion increased significantly following LW only(123.4±25.5 s),which was significantly greater(p=0.001)than the CG(24.3±18.5 s).By Week 48,the training-induced adaptations in the exercise groups returned to near baseline levels.Conclusion:Our study supports current physical-activity recommendations that 150 min/week of moderate-intensity exercise produces improvements in fitness in previously sedentary older individuals.Also,LW andWW elicit similar improvements in fitness if conducted at the same relative intensities.Exercise-na?ve older individuals can benefit from the lower impact forces and decreased risk of falls associated withWWwithout compromising improvements in cardiorespiratory fitness. | Andrew Haynes Louise H.Naylor Howard H.Carter Angela L.Spence Elisa Robey Kay L.Cox Barbara A.Maslen Nicola T.Lautenschlager Nicola D.Ridgers Daniel J.Green | 2020 | Journal of Sport and Health Science2020，9，3： | 2 |
| 4 | BMP Signaling in the Human Fetal Ovary is Developmentally Regulated and Promotes Primordial Germ Cell Apoptosis显示文摘 | Andrew J.Childs Hazel L.Kinnell Craig S.Collins KirstenHogg Rosemary A.L.Bayne Samira J.Green Alan S.McNeilly Richard A.Anderson | 2010 | STEM CELLS2010，，8： | 1 |
| 5 | State space sampling of feasible motions for high‐performance mobile robot navigation in complex environments显示文摘 | Thomas M.Howard Colin J.Green AlonzoKelly DaveFerguson | 2008 | J Field Robotics (鈥?)2008，，6： | 1 |
| 6 | Eye movement correlates of younger and older adults' strategies for complex addition显示文摘 | Heather J.Green Patrick Lemaire Stéphane Dufau | | 0，，03： | 1 |
| 7 | Constrained Sintering of Low‐Temperature Co‐Fired Ceramics显示文摘 | AravindMohanram Sang‐HoLee Gary L.Messing David J.Green | 2006 | Journal of the American Ceramic Society2006，，6： | 1 |
| 8 | Finance for small enterprise growth and poverty reduction in developing countries显示文摘 | Christopher J.Green Colin H.Kirkpatrick VictorMurinde | 2006 | J Int Dev2006，，7： | 1 |
| 9 | Sox2 induces glioblastoma cell sternness and tumor propagation by repressing TET2 and deregulating 5hmC and 5mC DNA modifications显示文摘DNA methylation is a reversible process catalyzed by the ten-eleven translocation(TET)family of enzymes(TET1,TET2,TET3)that convert 5-methylcytosine(5mC)to 5-hydroxymethylcytosine(5hmC).Altered patterns of 5hmC and 5mC are widely reported in human cancers and loss of 5hmC correlates with poor prognosis. | Hernando Lopez-Bertoni Amanda Johnson Yuan Rui Bachchu Lai Sophie Sail Maureen Malloy Jonathan BCoulter Maria Lugo-Fagundo Sweta Shudir Harmon Khela Christopher Caputo Jordan J.Green John Laterra | 2022 | Signal Transduction and Targeted Therapy2022，7，3： | 1 |
| 10 | Analyses of Globally Threatened Anatidae in Relation to Threats, Distribution, Migration Patterns, and Habitat Use显示文摘 | Andy J.Green | 2002 | Conservation Biology2002，，5： | 1 |
| 11 | Self-reported hypoglycemia and impact on quality of life and depression among adults with type 2 diabetes mellitus显示文摘 | Andrew J.Green Kathleen M Susan Grandy | | 0，，： | 1 |
| 12 | Promiscuity of fibroblast growth factor receptors显示文摘 | Paula J.Green Frank S.Walsh PatrickDoherty | 2005 | Bioessays2005，，8： | 1 |
| 13 | 南极洲万达盐湖中硼的分布和停留时间显示文摘万达盐湖位于南极横断山脉的赖特谷(77°32′S、161°31′E).湖呈东西向延伸,北、南两侧分别与阿斯加德和欧林巴斯山的高岩墙相接.湖区是由粗玄岩覆盖的、被煌斑岩侵入的中生代及古生代的花岗岩系组成.现代万达湖长5.6km、宽1.Skm,西侧最大水深68.8m.湖水面终年被厚4m的冰层所覆盖,冰面海拔123m. 万达湖是一典型的双季回水湖,湖水分两层,54m深以上水为淡水层。 | 于昇松 William J.Green | 1991 | 科学通报1991，36，4： | 0 |
| 14 | Protein-based profiling of the human IgA1 clonal repertoire revealed shared clones of serum polymeric IgA1 and milk secretory IgA1显示文摘Human adaptive immunity involves the production and secretion of antibodies by differentiated B cells(ie.,antibody-secreting cells,also called plasma cells)in response to antigens.These secreted antigen-specific antibodies are immunoglobulins that are present at substantial concentrations in blood,mucosal secretions,and breast milk.Structurally,human immunoglobulins consist of two identical heavy(H)chains and two identical light(L)chains that are connected by disulfide bridges to form a homodimer of heterodimers(ie.,H+Ll2).Each heterodimer consists of one H chain linked with one L chain,whereas the homodimer is formed by linking two H chains together.The genes for both the L and H chains are encoded by ligated gene segments that are genetically rearranged during V(D)J recombination,a process that endows each B cell with a unique receptor,giving rise to the enormous diversity of the B-cell antigen receptor repertoire. | Jan Novak Matthew B.Renfrow R.Glenn King Colin Reily Todd J.Green | 2023 | Cellular & Molecular Immunology2023，20，3： | 0 |
| 15 | Author Correction:Protein-based profiling of the human IgA1 clonal repertoire revealed shared clones of serum polymeric IgA1 and milk secretory IgA1显示文摘In the sentence beginning'H chain genes are assembled from one functional variable(B),one diversity(D),and..'in this article,the text should have read'H chain genes are assembled from one functional variable(M),one diversity(D),and..'. | Jan Novak Matthew B.Renfrow R.Glenn King Colin Reily Todd J.Green | 2023 | Cellular & Molecular Immunology2023，20，3： | 0 |
| 16 | Erratum to “BME 2.0: Engineering the Future of Medicine”显示文摘In the article“BME 2.0:Engineering the Future of Medicine”[1],the competing interests statement was inadvertently omitted by the publisher from the published version of the article.This has now been corrected in the PDF and HTML(full text). | Michael I.Miller Andrew O.Brightman Frederick H.Epstein K.Jane Grande-Allen Jordan J.Green Eileen Haase Cato T.Laurencin Elizabeth Logsdon Feilim Mac Gabhann Brenda Ogle Chun Wang George R.Wodicka Raimond L.Winslow | 2023 | Biomedical Engineering Frontiers2023，4，1： | 0 |
| 17 | BME 2.0: Engineering the Future of Medicine显示文摘If the 20th century was the age of mapping and controlling the external world,the 21st century is the biomedical age of mapping and controlling the biological internal world.The biomedical age is bringing new technological breakthroughs for sensing and controlling human biomolecules,cells,tissues,and organs,which underpin new frontiers in the biomedical discovery,data,biomanufacturing,and translational sciences.This article reviews what we believe will be the next wave of biomedical engineering(BME)education in support of the biomedical age,what we have termed BME 2.0.BME 2.0 was announced on October 122017 at BMES 49(http://gffzz3db2b265dafd4981so5fcnqkc5vxb6ocn.ffgz.tsg.suse.edu.cn/news-events/news/miller-opens-2017-bmes-annual-meeting-with-vision-for-new-bme-era/).We present several principles upon which we believe the BME 2.0 curriculum should be constructed,and from these principles,we describe what view as the foundations that form the next generations of curricula in support of the BME enterprise.The core principles of BME 2.0 education are(a)educate students bilingually,from day 1,in the languages of modern molecular biology and the analytical modeling of complex biological systems;(b)prepare every student to be a biomedical data scientist;(c)build a unique BME community for discovery and innovation via a vertically integrated and convergent learning environment spanning the university and hospital systems;(d)champion an educational culture of inclusive excellence;and(e)codify in the curriculum ongoing discoveries at the frontiers of the discipline,thus ensuring BME 2.0 as a launchpad for training the future leaders of the biotechnology marketplaces.We envision that the BME 2.0 education is the path for providing every student with the training to lead in this new era of engineering the future of medicine in the 21st century. | Michael I.Miller Andrew O.Brightman Frederick H.Epstein KJane Grande-Allen Jordan J.Green Eileen Haase Cato T.Laurencin Elizabeth Logsdon Feilim Mac Gabhann Brenda Ogle Chun Wang George R.Wodicka Raimond L.Winslow | 2023 | Biomedical Engineering Frontiers2023，4，1： | 0 |
| 18 | 18种阔叶树材积式系数的Stein准则估计显示文摘各种林木的单材积式有助于人们根据标准的资源清查数据估计蓄积量,在多种的混交林内,材积式通常是对每一树种构成的,但不同树种的材积估计式常表现出相似性,因此。 | Edwin J.Green 陈华豪 | 1989 | 国外林业1989，19，2： | 0 |
| 19 | Physiological strategies of moult-migrating Black-necked Grebes(Podiceps nigricollis)in a polluted staging site according to blood chemistry显示文摘After breeding,Black-necked Grebes(Podiceps nigricollis)perform a moult-migration to autumn hypersaline staging sites,where they moult the flight feathers and forage on superabundant brine shrimp(Artemia spp.)before leaving for wintering areas.During the stay in moulting sites,the grebes experience changes in organs and muscle size(atrophy,hypertrophy),and almost double their body mass,which has been suggested to act as an insurance against a collapse in prey availability in late autumn.During two years we collected blood samples from hundreds of individuals at one of the most important European moulting sites(the Odiel marshes,SW Spain),which is a highly polluted area due to mining drainage and chemical industry.We assessed the potential effect of moulting stage,day of the year and body condition on 16 blood biochemical parameters.Because of the changes in prey availability and body composition of grebes,we expected some physiological adjustments during moult.Elevated levels of cholesterol suggested that birds in active moult increased foraging effort to face the costs of moulting.There was increased amount of lactate dehydrogenase,corresponding to periods of breast muscle atrophy.Birds in active moult augmented protein ingestion,likely to account for the requirements of feather growth.We also show that the probability of fasting due to low prey availability increased late in the moulting season,as demonstrated by an increase in plasmaβ-hydroxy-butyrate. | Juan A.Amat Nico Varo Marta I.Sanchez Andy J.Green Damaso Hornero-Mendez Juan Garrido-Fernandez Cristina Ramo | 2023 | Avian Research2023，14，3： | 0 |
| 20 | Predicting an Athlete’s Physiological and Haematological Response to Live High-Train High Altitude Training Using a Hypoxic Sensitivity Test显示文摘Purpose Elite endurance runners frequently utilise live high-train high(LHTH)altitude training to improve endurance per-formance at sea level(SL).Individual variability in response to the hypoxic exposure have resulted in contradictory findings.In the present case study,changes in total haemoglobin mass(tHbmass)and physiological capacity,in response to 4-weeks of LHTH were documented.We tested if a hypoxic sensitivity test(HST)could predict altitude-induced adaptations to LHTH.Methods Fifteen elite athletes were selected to complete 4-weeks of LHTH(~2400 m).Athletes visited the laboratory for preliminary testing(PRE),to determine lactate threshold(LT),lactate turn point(LTP),maximal oxygen uptake VO_(2max)and tHbmass.During LHTH,athletes completed daily physiological measures[arterial oxygen saturation(SpO2)and body mass]and subjective wellbeing questions.Testing was repeated,for those who completed the full camp,post-LHTH(POST).Additionally,athletes completed the HST prior to LHTH.Results A difference(P<0.05)was found from PRE to POST in average tHbmass(1.8%±3.4%),VO_(2max)(2.7%±3.4%),LT(6.1%±4.6%)and LTP(5.4%±3.8%),after 4-weeks LHTH.HST revealed a decrease in oxygen saturation at rest(ΔSp_(r))and higher hypoxic ventilatory response at rest(HVRr)predicted individual changes tHbmass.Lower hypoxic cardiac response at rest(HCRr)and higher HVRr predicted individual changes VO_(2max).Conclusion Four weeks of LHTH at~2400 m increased tHbmass and enhanced physiological capacity in elite endurance runners.There was no observed relationship between these changes and baseline characteristics,pre-LHTH serum ferritin levels,or reported incidents of musculoskeletal injury or illness.The HST did however,estimate changes in tHbmass and VO_(2max).HST prior to LHTH could allow coaches and practitioners to better inform the acclimatisation strategies and train-ing load application of endurance runners at altitude. | Gareth Turner Kate L.Spilsbury David J.Green Barry W.Fudge Jamie S.M.Pringle Alan J.Richardson Neil S.Maxwell | 2022 | Journal of Science in Sport and Exercise2022，4，4： | 0 |
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