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| 1 | Management of early gastrointestinal neuroendocrine neoplasms显示文摘Neuroendocrine neoplasms (NENs) of the stomach, duo- denum, appendix or rectum that are small (≤ 1 cm) and well differentiated can be considered 'early' tumors, since they generally have a (very) good prognosis. In the new WHO classification of 2010, these neoplasms are called neuroendocrine tumors/ carcinoids (NETs), grade (G) 1 or 2, and distinguished from poorly differentiated neuroendocrine carcinomas (NECs), G3. NETs are increasing, with a rise in the age-adjusted incidence in the U.S.A. by about 700 % in the last 35 years. Improved early detection seems to be the main reason for these epidemiological changes. Both the better generalavailability of endoscopy, and imaging techniques, have led to a shift in the discovery of smaller-sized (≤ 10-20 mm) intestinal NETs/carcinoids and earlier tumor stages at diagnosis. Endoscopic screening is therefore effective in the early diagnosis, not only of colorectal adenocarcinomas, but also of NETs/carcinoids. Endoscopic removal, followed up with endoscopic surveillance is the treatment of choice in NETs/carcinoids of the stomach, duodenum and rectum that are ≤ 10 mm in size, have a low proliferative activity (G1), do not infiltrate the muscular layer and show no angioinvasion. In all the other intestinal NENs, optimal treatment generally needs surgery and/or medical therapy depending on type, biology and stage of the tumor, as well as the individual situation of the patient. | Hans Scherübl Robert T Jensen Guillaume Cadiot Ulrich Stlzel Günter Klppel | 2011 | World Journal of Gastrointestinal Endoscopy2011，3，7： | 13 |
| 2 | Neuroendocrine tumors of the small bowels are on the rise:Early aspects and management显示文摘Neuroendocrine tumors of the small bowel are on the rise. In the US they have increased by 300%-500% in the last 35 years. At the same time their prognosis is much improved. Today,most neuroendocrine tumors (NETs) of the duodenum are detected 'incidentally' and therefore recognized at an early stage. Duodenal NETs which are well differentiated,not larger than 10 mm and limited to the mucosa/submucosa can be endoscopically resected. The management of duodenal NETs ranging between 10 and 20 mm needs an interdisciplinary discussion. Endoscopic ultrasound is the method of choice to determine tumor size and depth of infiltration. Surgery is recommended for well-differentiated duodenal NET tumors greater than 20 mm,for localized sporadic gastrinomas (of any size) and for localized poorly differentiated NE cancers. Surgery is recommended for any ileal NET. Advanced ileal NETs with a carcinoid syndrome are treated with longacting somatostatin analogs. This treatment significantly improves (progression-free) survival in patients with metastatic NETs of the ileum. For optimal NET management,tumor biology,type,localization and stage of the neoplasm,as well as the patient's individual circumstances have to be taken into account. | Hans Scherbl Robert T Jensen Guillaume Cadiot Ulrich Stlzel Gnter Klppel | 2010 | World Journal of Gastrointestinal Endoscopy2010，2，10： | 10 |
| 3 | Adaptations to environmental stresses显示文摘 | Hans J Bohnert Nelson D E Jensen R G | 1995 | Plant cell1995，7，： | 1 |
| 4 | Loss of Interleukin-10 Signaling and Infantile Inflammatory Bowel Disease: Implications for Diagnosis and Therapy显示文摘 | Daniel Kotlarz Rita Beier Dhaarini Murugan Jana Diestelhorst Ole Jensen Kaan Boztug Dietmar Pfeifer Hans Kreipe Eva–Doreen Pfister Ulrich Baumann Jacek Puchalka Jens Bohne Odul Egritas Buket Dalgic Kaija–Leena Kolho Axel Sauerbrey Stephan Buderus Tayfun G | 2012 | Gastroenterology2012，，2： | 1 |
| 5 | Loss of Interleukin-10 Signaling and Infantile Inflammatory Bowel Disease: Implications for Diagnosis and Therapy显示文摘 | Daniel Kotlarz Rita Beier Dhaarini Murugan Jana Diestelhorst Ole Jensen Kaan Boztug Dietmar Pfeifer Hans Kreipe Eva–Doreen Pfister Ulrich Baumann Jacek Puchalka Jens Bohne Odul Egritas Buket Dalgic Kaija–Leena Kolho Axel Sauerbrey Stephan Buderus Tayfun G | 2012 | Gastroenterology2012，，2： | 1 |
| 6 | Trade policy responses to food price crisis and implications for existing domestic support measures: the case of China in 2008显示文摘 | Yu Wusheng Jensen Hans G | 2014 | Word Trade Review2014，13，4： | 1 |
| 7 | High-sensitivity C-reactive protein and N-terminal pro-B-type natriuretic peptide in patients with stable coronary artery disease: a prognostic study within the CLARICOR Trial显示文摘 | Marina J. Harutyunyan Anders B. Mathiasen Per Winkel Jens P. G? tze J? rgen Fischer Hansen Per Hildebrandt Gorm Boje Jensen J? rgen Hilden Christian M. Jespersen Erik Kj? ller Hans J. Kolmos Christian Gluud Jens Kastrup | 2011 | Scandinavian Journal of Clinical & Laboratory Inv2011，，1： | 1 |
| 8 | Formation of the tight-binding inhibitor, 3-ketoarabinitol-1,5-bisphosphate by ribulose-1,5-bisphosphate carboxylase/oxygenase is O2-dependent显示文摘 | Genhai Zhu Hans J. Bohnert Richard G. Jensen Günter F. Wildner | 1998 | Photosynthesis Research1998，，1： | 1 |
| 9 | Adaptations to envi-ronmental stresses显示文摘 | Hans J B Nelson D E Jensen R G | 1995 | Plant Cell1995，，7： | 1 |
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