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| 1 | Distribution, geochemistry and age of the Millennium eruptives of Changbaishan volcano, Northeast China - A review显示文摘大爆炸暴烈的爆发产生为识别火山的来源提供有利条件的广泛的地区性的 tephra 存款,比较一个区域的沉积阶层并且决定他们的年龄。tephra 层,叫作 B-Tm,由 Changbaishan 火山的千年爆发产生了,广泛地在东北中国,日本, D.P.R 朝鲜,和俄国的附近沿海的区域被散布。它形成普遍东北亚洲人阶层的部分并且为建立一个等时的 stratigraphic 框架是重要的。然而,用这 tephra 层在时间的描述和联系阶层的 stratigraphic 关联上研究主要被集中在并且在日本附近。在东北中国,这 tephra 层很少被看见,它在 stratigraphic 关联的申请甚至更稀罕。更重要地,为远侧、近似的 tephras 的精确年龄的决心被辩论了,导致在它的环境影响的讨论的争吵。从这爆发通常发生在 1,012 和 1,004 cal 年 BP 之间的远侧、近似的 Changbaishan 灰表演的 Stratigraphic 记录。在在日本附近的 Changbaishan 灰和第四级的普遍的灰之间的 Geochemical 比较说明 Changbaishan 灰是从 rhyolitic 的一篇连续作文到 trachytic 和它到 CaO 的 FeO ^潜水艇 T ^的比率,这通常比 4 大,它能在全球当代的爆发之中被用作一个区分的标识符[出版摘要] | Chunqing SUN Haitao YOU Jiaqi LIU Xin LI Jinliang GAO Shuangshuang CHEN | 2014 | Frontiers of Earth Science2014，8，2： | 10 |
| 2 | Trot Gait Design and CPG Method for a Quadruped Robot显示文摘 | Jiaqi Zhang Feng Gao Xiaolei Han Xianbao Chen Xueying Han | 2014 | Journal of Bionic Engineering2014，11，1： | 7 |
| 3 | New innovations in pavement materials and engineering:A review on pavement engineering research 2021显示文摘Sustainable and resilient pavement infrastructure is critical for current economic and environmental challenges.In the past 10 years,the pavement infrastructure strongly supports the rapid development of the global social economy.New theories,new methods,new technologies and new materials related to pavement engineering are emerging.Deterioration of pavement infrastructure is a typical multi-physics problem.Because of actual coupled behaviors of traffic and environmental conditions,predictions of pavement service life become more and more complicated and require a deep knowledge of pavement material analysis.In order to summarize the current and determine the future research of pavement engineering,Journal of Traffic and Transportation Engineering(English Edition)has launched a review paper on the topic of'New innovations in pavement materials and engineering:A review on pavement engineering research 2021'.Based on the joint-effort of 43 scholars from 24 well-known universities in highway engineering,this review paper systematically analyzes the research status and future development direction of 5 major fields of pavement engineering in the world.The content includes asphalt binder performance and modeling,mixture performance and modeling of pavement materials,multi-scale mechanics,green and sustainable pavement,and intelligent pavement.Overall,this review paper is able to provide references and insights for researchers and engineers in the field of pavement engineering. | JTTE Editorial Office Jiaqi Chen Hancheng Dan Yongjie Ding Yangming Gao Meng Guo Shuaicheng Guo Bingye Han Bin Hong Yue Hou Chichun Hu Jing Hu Ju Huyan Jiwang Jiang Wei Jiang Cheng Li Pengfei Liu Yu Liu Zhuangzhuang Liu Guoyang Lu Jian Ouyang Xin Qu Dongya Ren Chao Wang Chaohui Wang Dawei Wang Di Wang Hainian Wang Haopeng Wang Yue Xiao Chao Xing Huining Xu Yu Yan Xu Yang Lingyun You Zhanping You Bin Yu Huayang Yu Huanan Yu Henglong Zhang Jizhe Zhang Changhong Zhou Changjun Zhou Xingyi Zhu | 2021 | Journal of Traffic and Transportation Engineering(English Edition)2021，8，6： | 7 |
| 4 | Imputation from SNP chip to sequence: a case study in a Chinese indigenous chicken population显示文摘Background: Genome-wide association studies and genomic predictions are thought to be optimized by using whole-genome sequence(WGS) data. However, sequencing thousands of individuals of interest is expensive.Imputation from SNP panels to WGS data is an attractive and less expensive approach to obtain WGS data. The aims of this study were to investigate the accuracy of imputation and to provide insight into the design and execution of genotype imputation.Results: We genotyped 450 chickens with a 600 K SNP array, and sequenced 24 key individuals by whole genome re-sequencing. Accuracy of imputation from putative 60 K and 600 K array data to WGS data was 0.620 and 0.812 for Beagle, and 0.810 and 0.914 for FImpute, respectively. By increasing the sequencing cost from 24 X to 144 X, the imputation accuracy increased from 0.525 to 0.698 for Beagle and from 0.654 to 0.823 for FImpute. With fixed sequence depth(12 X), increasing the number of sequenced animals from 1 to 24, improved accuracy from 0.421 to0.897 for FImpute and from 0.396 to 0.777 for Beagle. Using optimally selected key individuals resulted in a higher imputation accuracy compared with using randomly selected individuals as a reference population for resequencing. With fixed reference population size(24), imputation accuracy increased from 0.654 to 0.875 for FImpute and from 0.512 to 0.762 for Beagle as the sequencing depth increased from 1 X to 12 X. With a given total cost of genotyping, accuracy increased with the size of the reference population for FImpute, but the pattern was not valid for Beagle, which showed the highest accuracy at six fold coverage for the scenarios used in this study.Conclusions: In conclusion, we comprehensively investigated the impacts of several key factors on genotype imputation. Generally, increasing sequencing cost gave a higher imputation accuracy. But with a fixed sequencing cost, the optimal imputation enhance the performance of WGP and GWAS. An optimal imputation strategy should take size of reference population, imputation algorithms, marker density, and population structure of the target population and methods to select key individuals into consideration comprehensively. This work sheds additional light on how to design and execute genotype imputation for livestock populations. | Shaopan Ye Xiaolong Yuan Xiran Lin Ning Gao Yuanyu Luo Zanmou Chen Jiaqi Li Xiquan Zhang Zhe Zhang | 2018 | Journal of Animal Science and Biotechnology2018，9，2： | 6 |
| 5 | Mesenchymal stem cell treatment improves outcome of COVID-19 patients via multiple immunomodulatory mechanisms显示文摘The infusion of coronavirus disease 2019(COVID-19)patients with mesenchymal stem cells(MSCs)potentially improves clinical symptoms,but the underlying mechanism remains unclear.We conducted a randomized,single-blind,placebo-controlled(29 patients/group)phase II clinical trial to validate previous findings and explore the potential mechanisms.Patients treated with umbilical cord-derived MSCs exhibited a shorter hospital stay(P=0.0198)and less time required for symptoms remission(P=0.0194)than those who received placebo.Based on chest images,both severe and critical patients treated with MSCs showed improvement by day 7(P=0.0099)and day 21(P=0.0084).MSC-treated patients had fewer adverse events.MSC infusion reduced the levels of C-reactive protein,proinflammatory cytokines,and neutrophil extracellular traps(NETs)and promoted the maintenance of SARS-CoV-2-specific antibodies.To explore how MSCs modulate the immune system,we employed single-cell RNA sequencing analysis on peripheral blood.Our analysis identified a novel subpopulation of VNN2+hematopoietic stem/progenitorlike(HSPC-like)cells expressing CSF3R and PTPRE that were mobilized following MSC infusion.Genes encoding chemotaxis factors—CX3CR1 and L-selectin—were upregulated in various immune cells.MSC treatment also regulated B cell subsets and increased the expression of costimulatory CD28 in T cells in vivo and in vitro.In addition,an in vivo mouse study confirmed that MSCs suppressed NET release and reduced venous thrombosis by upregulating kindlin-3 signaling.Together,our results underscore the role of MSCs in improving COVID-19 patient outcomes via maintenance of immune homeostasis. | Rongjia Zhu Tingdong Yan Yingmei Feng Yan Liu Hongcui Cao Gongxin Peng Yanlei Yang Zhen Xu Jingqi Liu Wei Hou Xiaoyue Wang Zhe Li Luchan Deng Shihua Wang Jing Li Qin Han Hongling Li Guangliang Shan Yinghao Cao Xingyan An Jianshe Yan Zhonghui Zhang Huafei Li Xuebin Qu Jiaqi Zhu Shumin Zhou Jiao Wang Fengchun Zhang Jinming Gao Ronghua Jin Dayong Xu Yan-Qing Ma Tao Huang Shuang Peng Zhi Zheng Ilia Stambler Eric Gilson Lee Wei Lim Alexey Moskalev Antonio Cano Sasanka Chakrabarti Brun Ulfhake Huanxing Su Haoying Xu Sihuan Xu Feng Wei Holly MBrown-Borg Kyung-Jin Min Georgina Ellison-Hughes Calogero Caruso Kunlin Jin Robert Chunhua Zhao | 2021 | Cell Research2021，31，12： | 5 |
| 6 | Attribution analysis based on Budyko hypothesis for land evapotranspiration change in the Loess Plateau, China显示文摘Land evapotranspiration(ET) is an important process connecting soil, vegetation and the atmosphere, especially in regions that experience shortage in precipitation.Since 1999, the implementation of a large-scale vegetation restoration project has significantly improved the ecological environment of the Loess Plateau in China.However, the quantitative assessment of the contribution of vegetation restoration projects to long-term ET is still in its infancy.In this study, we investigated changes in land ET and associated driving factors from 1982 to 2014 in the Loess Plateau using Budyko-based partial differential methods.Overall, annual ET slightly increased by 0.28 mm/a and there were no large fluctuations after project implementation.An attribution analysis showed that precipitation was the driving factor of inter-annual variability of land ET throughout the study period;the average impacts of precipitation, potential evapotranspiration, and vegetation restoration on ET change were 61.5%, 11.5% and 26.9%, respectively.These results provide an improved understanding of the relationship between vegetation condition change and climate variation on terrestrial ET in the study area and can support future decision-making regarding water resource availability. | HE Guohua ZHAO Yong WANG Jianhua GAO Xuerui HE Fan LI Haihong ZHAI Jiaqi WANG Qingming ZHU Yongnan | 2019 | Journal of Arid Land2019，11，6： | 5 |
| 7 | Size fraction of phytoplankton and the contribution of natural plankton to the carbon source of Zhikong scallop Chlamys farreri in mariculture ecosystem of the Sanggou Bay显示文摘The biomass and size fraction of phytoplankton in terms of chlorophyll a(Chl a) was measured during four cruises conducted in April, July, October 2013 and January 2014 in mariculture area, the Sanggou Bay, China.Results show that total Chl a levels in the surface seawater of the Sanggou Bay generally range from 0.10 to 20.46μg/L, with an average value of 2.13 μg/L. Nano-phytoplankton was the most important size-fraction and accounted for about 65.1% of total Chl a. In order to evaluate the importance of the 'protozoan trophic link' for energy transfer from the microbial loop to filter-feeding feeders, Zhikong scallop Chlamys farreri was then offered a natural planktonic community as potential prey. Results show that scallops obtained carbon source from natural plankton with the rate of 11 033.05 μg/(g·d). Protists(nanoflagellates and ciliates) were the dominant source of carbon retained by scallop(48.78%). The microbial loop provided 58.45% of the carbon source for farmed scallops. These results indicate that the microbial loop represent a valuable trophic resource in mariculture system of the Sanggou Bay. | JIANG Zengjie DU Meirong FANG Jinghui GAO Yaping LI Jiaqi ZHAO Li FANG Jianguang | 2017 | Acta Oceanologica Sinica2017，36，10： | 4 |
| 8 | Bifunctional Oxygen Electrocatalyst of Mesoporous Ni/NiO Nanosheets for Flexible Rechargeable Zn–Air Batteries显示文摘One approach to accelerate the stagnant kinetics of both the oxygen reduction and evolution reactions(ORR/OER)is to develop a rationally designed multiphase nanocomposite,where the functions arising from each of the constituent phases,their interfaces,and the overall structure are properly controlled.Herein,we successfully synthesized an oxygen electrocatalyst consisting of Ni nanoparticles purposely interpenetrated into mesoporous NiO nanosheets(porous Ni/NiO).Benefiting from the contributions of the Ni and NiO phases,the well-established pore channels for charge transport at the interface between the phases,and the enhanced conductivity due to oxygen-deficiency at the pore edges,the porous Ni/NiO nanosheets show a potential of 1.49 V(10 mA cm^-2)for the OER and a half-wave potential of 0.76 V for the ORR,outperforming their noble metal counterparts.More significantly,a Zn-air battery employing the porous Ni/NiO nanosheets exhibits an initial charging-discharging voltage gap of 0.83 V(2 mA cm^-2),specific capacity of 853 mAh gZn^-1 at 20 mA cm^-2,and long-time cycling stability(120 h).In addition,the porous Ni/NiO-based solid-like Zn-air battery shows excellent electrochemical performance and flexibility,illustrating its great potential as a next-generation rechargeable power source for flexible electronics. | Peitao Liu Jiaqi Ran Baorui Xia Shibo Xi Daqiang Gao John Wang | 2020 | Nano-Micro Letters2020，12，5： | 4 |
| 9 | Effect of Qiangxin Huoli decoction on rats with adriamycin-induced chronic heart failure显示文摘OBJECTIVE: To investigate the effect of Qiangxin Huoli decoction on rats with chronic heart failure(CHF) induced by adriamycin(ADR), and to investigate the underlying mechanism of this effect.METHODS: Ninety-six healthy Wistar rats were divided into six groups: control, CHF model, CHF treated by Shenfu injection, and three CHF groups treated with Qiangxin Huoli decoction at high, medium, and low doses, respectively. Qiangxin Huoli decoction was administered orally to protect the stomach in the three Qiangxin Huoli decoction groups, while the control group and the CHF model group were administered the same volume of 0.9% physiological saline, and the Shenfu group wereadministered the same volume of Shenfu injection. Ten days later, the CHF model was then induced in all groups except the control group by intraperitoneal injection of ADR at gradient dose intervals. The bodyweights were recorded on days 10, 20, 30, and 40. Hemodynamic indices were recorded, including left ventricular systolic pressure(LVSP), left ventricular end-diastolic pressure(LVEDP), maximum increase in left ventricular pressure(+dp/dt_(max)), maximum decrease in left ventricular pressure(-dp/dt_(max)), heart rate(HR), and electrocardiogram using an eight-channel physiological recorder with LabChart software monitoring. The plasma brain natriuretic peptide(BNP) concentration was determined by enzyme-linked immunosorbent adsorption. The expressions of B-cell lymphoma-2(Bcl-2) and Bcl-2-associated X protein(Bax) were detected by immunohistochemical methods.RESULTS: The CHF model group were in poor condition, and the mean bodyweight was significantly decreased compared with the control group. Furthermore, compared with the control group, the CHF groups had significantly decreased LVSP, +dp/dt_(max), and-dp/dt_(max), and significantly increased LVEDP. The CHF groups also showed significant increases in HR, S-T segment elevation, and plasma BNP levels compared with the control group. Compared with the CHF model group, the treatment groups had significantly increased Bax expression(P < 0.05) and significantly decreased Bcl-2 expression(P < 0.01), indicating less apoptosis. The high dose Qiangxin Huoli decoction group and the Shenfu group showed the most significant improvements.CONCLUSION: In the rat model of CHF, Qiangxin Huoli decoction significantly reduces the abnormal hemodynamics, improves cardiac function, reduces plasma BNP concentration, regulates the expression of apoptosis proteins, inhibits the apoptosis of myocardial cells, and plays a protective role. | Gao Ling Yang Ting Zhu Jiaqi Xu Lei Su Li Wang Di | 2019 | Journal of Traditional Chinese Medicine2019，39，1： | 4 |
| 10 | CO2 emission driving forces and corresponding mitigation strategies under low-carbon economy mode:evidence from China's Beijing-Tianjin-Hebei region显示文摘On account of the background of China's 'new normal' characterized by slower economic growth, this paper analyses the low-carbon economy status quo in the Beijing-Tianjin-Hebei region and empirically investigates the relationship between carbon dioxide(CO_2) emissions and its various factors for China's Beijing-Tianjin-Hebei region using panel data econometric technique. We find evidence of existence of Environmental Kuznets Curve. Results also show that economic scale, industrial structure, and urbanization rate are crucial factors to promote CO_2emissions. However, technological progress, especially the domestic independent research and development, plays a key role in C0_2 emissions abatement. Next, we further analyze the correlation between each subregion and various factors according to Grey Relation Analysis. Thereby,our findings provide important implications for policymakers in air pollution control and C0_2 emissions reduction for this region. | Weixian Wei Peng Li Siyu Wang Jiaqi Gao | 2017 | Chinese Journal of Population,Resources and Environment2017，15，2： | 3 |
| 11 | Negative thermal expansion: Mechanisms and materials显示文摘Negative thermal expansion(NTE)of materials is an intriguing phenomenon challenging the concept of traditional lattice dynamics and of importance for a variety of applications.Progresses in this field develop markedly and update continuously our knowledge on the NTE behavior of materials.In this article,we review the most recent understandings on the underlying mechanisms(anharmonic phonon vibration,magnetovolume effect,ferroelectrorestriction and charge transfer)of thermal shrinkage and the development of NTE materials under each mechanism from both the theoretical and experimental aspects.Besides the low frequency optical phonons which are usually accepted as the origins of NTE in framework structures,NTE driven by acoustic phonons and the interplay between anisotropic elasticity and phonons are stressed.Based on the data documented,some problems affecting applications of NTE materials are discussed and strategies for discovering and design novel framework structured NET materials are also presented. | Erjun Liang Qiang Sun Huanli Yuan Jiaqi Wang Gaojie Zeng Qilong Gao | 2021 | Frontiers of physics2021，16，5： | 3 |
| 12 | Robotic single-incision left hemihepatectomy for intrahepatic bile duct stones by Da Vinci single-site surgical system: A case report with video显示文摘Minimally invasive surgery is a trend in hepatobiliary surgery.A 56-year-old female patient was admitted to our institution for intrahepatic lithiasis.The CT scan showed multiple calculi in the left liver,dilation of the left intrahepatic bile duct and liver atrophy of the left lobe.Robotic single-incision left hemihepatectomy by the single-site systemwas successfully applied.With the idea of enhanced recovery after surgery,the patient was discharged on the third day after the operation without any morbidity.Robotic single-incision surgery is more frequent in gynecologic and urological surgery.As far as we know,this is the first robotic single-incision left hemihepatectomy report in the world. | Xiao Liang Junhao Zheng Jiaqi Gao Yubin Sheng Tianyu Lin Xiujun Cai | 2021 | Laparoscopic, Endoscopic and Robotic Surgery2021，4，3： | 3 |
| 13 | The origin of invasion of an alien frog species in Tibet, China显示文摘 | Supen WANG Liqing FAN Conghui LIU Jiaqi LI Xu GAO Wei ZHU Yiming LI | 2017 | Current Zoology2017，63，6： | 2 |
| 14 | Mechanism of Varve Formation and Paleoenvironmental Research at Lake Bolterskardet, Svalbard, the Arctic显示文摘根据薄片和 ^(137 ) 的观察 C 数据,在沉积的迭合被解释是在博尔特斯卡德特·莱克的纹泥(78 deg 06'' N, 16 deg 01'' E ) , Svalbard,北极。纹泥作为黑暗淤泥的 andlight 泥土层的两行诗出现在一台岩石学的显微镜下面。纹泥形成的机制如下是 surmized:每淤泥层是当主要在夏天期间源于融雪,解释的沉积流入的生产;每泥土层在一个冰封面时期期间在静止的水环境被扔。轻粘土层提供重要标准层识别年度接口。高累积率,冰层的长时期,并且地形的封闭盆地可能是所有关键因素处于良好的竟技状态并且保存纹泥。纹泥厚度被知道主要被夏天温度控制。在博尔特斯卡德特湖的纹泥厚度的 Thevariation 然后能被用来重建夏天温度。有在过去的 150 年的夏天温度的不同十年规模可变性的纹泥系列表演。温暖的时期发生在 1860 年代,在 1900 附近, 1930s,1950s,和 1970 年代,并且在最后 20 年里。博尔特斯卡德湖的 varved 沉积在这 data-sparsearea 为高分辨率的 paleodimatk 和 paleoenvironmental 研究保存一个理想的记录。 | CHU Guoqiang LIU Jiaqi GAO Denyi SUN Qing | 2006 | Acta Geologica Sinica(English Edition)2006，80，4： | 1 |
| 15 | Theoretical modeling and experimental verifications of the single-compressor-driven three-stage Stirling-type pulse tube cryocooler显示文摘This paper establishes a theoretical model of the single-compressor-driven (SCD) three-stage Stirlingtype pulse tube cryocooler (SPTC) and conducts experimental verifications. The main differences between the SCD type and the multi-compressor-driven (MCD) crycooler are analyzed, such as the distribution of the input acoustic power in each stage and the optimization of the operating parameters, in which both advantages and difficulties of the former are stressed. The effects of the dynamic temperatures are considered to improve the accuracy of the simulation at very low temperatures, and a specific simulation example aiming at 10 K is given in which quantitative analyses are provided. A SCD threestage SPTC is developed based on the theoretical analyses and with a total input acoustic power of 371.58 W, which reaches a no-load temperature of 8.82 K and can simultaneously achieve the cooling capacities of 2.4 W at 70 K, 0.17 W at 25 K, and 0.05 W at 10 K. The performance of the SCD three-stage SPTC is slightly poorer than that of its MCD counterpart developed in the same laboratory, but the advantages of lightweight and compactness make the former more attractive to practical applications. | Haizheng DANG Dingli BAO Zhiqian GAO Tao ZHANG Jun TAN Rui ZHA Jiaqi LI Ning LI Yongjiang ZHAO Bangjian ZHAO | 2019 | Frontiers in Energy2019，13，3： | 1 |
| 16 | A novel strategy of lithium recycling from spent lithium-ion batteries using imidazolium ionic liquid显示文摘In light of the increasing demand for environmental protection and energy conservation,the recovery of highly valuable metals,such as Li,Co,and Ni,from spent lithium-ion batteries(LIBs)has attracted widespread attention.Most conventional recycling strategies,however,suffer from a lack of lithium recycling,although they display high efficiency in the recovery of Co and Ni.In this work,we report an efficient extraction process of lithium from the spent LIBs by using a functional imidazolium ionic liquid.The extraction efficiency can be reached to 92.5%after a three-stage extraction,while the extraction efficiency of Ni-Co-Mn is less than 4.0%.The new process shows a high selectivity of lithium ion.FTIR spectroscopy and ultraviolet are utilized to characterize the variations in the functional groups during extraction to reveal that the possible extraction mechanism is cation exchange.The results of this work provide an effective and sustainable strategy of lithium recycling from spent LIBs. | Hongshuai Zheng Jiaqi Huang Tao Dong Yifan Sha Haitao Zhang Jie Gao Suojiang Zhang | 2022 | Chinese Journal of Chemical Engineering2022，35，1： | 1 |
| 17 | A hybrid model for short-term rainstorm forecasting based on a back-propagation neural network and synoptic diagnosis显示文摘暴雨是我国最重要的自然灾害之一.大量的研究表明,暴雨的频率和强度在全球变暖的背景下正在逐年增强.但是如何成功的预测短期暴雨,特别是发生在复杂地形下的暴雨,仍然是一个巨大的挑战.本项研究采用BP神经网络和天气学诊断相结合的方法,探索了一种四川盆地西部复杂地形下的暴雨预报模型.该模型有效改善了喇叭口地形下,受低层偏东风影响的暴雨预报准确性.机器学习与天气学理论的结合,提升了模型的物理基础和预测成功率,同时该方法也为发展具有本地特征的暴雨预报客观工具,提供了一定的参考价值. | Guolu Gao Yang Li Jiaqi Li Xueyun Zhou Ziqin Zhou | 2021 | Atmospheric and Oceanic Science Letters2021，14，5： | 1 |
| 18 | Direct hydroxylation of benzene to phenol over a new vanadium-substituted phosphomolybdate as a solid catalyst显示文摘 | Jiaqi Chen Shuang Gao Jie Xu | 2007 | Catalysis Communications2007，，5： | 1 |
| 19 | Dynamic shielding of bacterial outer membrane vesicles for safe and efficient chemo-immunotherapy against tumors显示文摘Bacterial outer membrane vesicles(OMVs)are potent immunostimulants of regulating the tumor microenvironment(TME)for immunotherapy,and can be used to deliver drugs.However,the severe systemic inflammatory response triggered by OMVs upon intravenous(i.v.)injection has limited their application.Here,we developed a safe and effective strategy by conjugating doxorubicin-loaded serum albumin(SA-DOX,AD)onto the surface of OMVs using a matrix metalloproteinase(MMP)-cleavable peptide linker(cL).This approach enabled the dynamic shielding of OMVs to reduce the systemic side effects while simultaneously enhancing the anti-tumor effects through chemo-immunotherapy.Specifically,the resulting OMV-cL-AD formulation exhibited significantly enhanced accumulation at the tumor site after i.v.administration,facilitated by the SA decoration on the OMVs surface.Subsequently,the shield on the OMV-cL-AD was cleaved by the over-expressed MMP in the TME,leading to the release of both OMVs and AD.This process provided OMV-induced immunotherapy and DOX-induced chemotherapy,resulting in synergistic tumor inhibition.In conclusion,our work demonstrated the potential of OMV-cL-AD as an effective immunochemotherapy strategy that can prolong the survival time of mice without inducing side effects. | Shuping Li Xin Li Jiaqi Meng Weier Bao Shuang Wang Peng Ye Xiao-Dong Gao Wei Wei | 2024 | Nano Research2024，17，2： | 1 |
| 20 | Oxygen vacancy-mediated WO_(3) phase junction to steering photogenerated charge separation for enhanced water splitting显示文摘Effective charge separation and transfer is deemed to be the contributing factor to achieve high photoelectrochemical(PEC)water splitting performance on photoelectrodes.Building a phase junction structure with controllable phase transition of WO_(3) can further improve the photocatalytic performance.In this work,we realized the transition from orthorhombic to monoclinic by regulating the annealing temperatures,and constructed an orthorhombic–monoclinic WO_(3)(o-WO_(3)/m-WO_(3))phase junction.The formation of oxygen vacancies causes an imbalance of the charge distribution in the crystal structure,which changes the W–O bond length and bond angle,accelerating the phase transition.As expected,an optimum PEC activity was achieved over the o-WO_(3)/m-WO_(3) phase junction in WO_(3)-450 photoelectrode,yielding the maximum O_(2) evolution rate roughly 32 times higher than that of pure WO_(3)-250 without any sacrificial agents under visible light irradiation.The enhancement of catalytic activity is attributed to the atomically smooth interface with a highly matched lattice and robust built-in electric field around the phase junction,which leads to a less-defective and abrupt interface and provides a smooth interfacial charge separation and transfer path,leading to improved charge separation and transfer efficiency and a great enhancement in photocatalytic activity.This work strikes out on new paths in the formation of an oxygen vacancy-induced phase transition and provides new ideas for the design of catalysts. | Huimin LI Qianqian SHEN Han ZHANG Jiaqi GAO Husheng JIA Xuguang LIU Qi LI Jinbo XUE | 2022 | Journal of Advanced Ceramics2022，11，12： | 1 |
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