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| 1 | Recent advances in diagnostic upper endoscopy显示文摘BACKGROUND Esophageo-gastro-duodenoscopy(EGD)is an important procedure used for detection and diagnosis of esophago-gastric lesions.There exists no consensus on the technique of examination.AIM To identify recent advances in diagnostic EGDs to improve diagnostic yield.METHODS We queried the PubMed database for relevant articles published between January 2001 and August 2019 as well as hand searched references from recently published endoscopy guidelines.Keywords used included free text and MeSH terms addressing quality indicators and technological innovations in EGDs.Factors affecting diagnostic yield and EGD quality were identified and divided into the follow segments:Pre endoscopy preparation,sedation,examination schema,examination time,routine biopsy,image enhanced endoscopy and future developments.RESULTS We identified 120 relevant abstracts of which we utilized 67 of these studies in our review.Adequate pre-endoscopy preparation with simethicone and pronase increases gastric visibility.Proper sedation,especially with propofol,increases patient satisfaction after procedure and may improve detection of superficial gastrointestinal lesions.There is a movement towards mandatory picture documentation during EGD as well as dedicating sufficient time for examination improves diagnostic yield.The use of image enhanced endoscopy and magnifying endoscopy improves detection of squamous cell carcinoma and gastric neoplasm.The magnifying endoscopy simple diagnostic algorithm is useful for diagnosis of early gastric cancer.CONCLUSION There is a steady momentum in the past decade towards improving diagnostic yield,quality and reporting in EGDs.Other interesting innovations,such as Raman spectroscopy,endocytoscopy and artificial intelligence may have widespread endoscopic applications in the near future. | Jun-Liang Teh Asim Shabbir Soon Yuen Jimmy Bok-Yan So | 2020 | World Journal of Gastroenterology2020，26，4： | 15 |
| 2 | Muco-submucosal elongated polyps of the gastrointestinal tract:A case series and a review of the literature显示文摘We present three cases of gastrointestinal muco-submucosal elongated polyps,two located in the duodenum and one in the descending colon.All three cases had a characteristic,'worm-like' endoscopic appearance and were lined by unremarkable mucosa.The vascular component was located in the submucosa and was composed of a mixture of variably dilated blood vessels(capillaries and veins) and lymphatics.The duodenal polyps displayed lipomatous metaplasia of the submucosal stroma.The dual vascular phenotype of the vascular component was confirmed by immunohistochemistry with D2-40 and CD31. | Char Loo Tan Sze Hwa Tan Jimmy BY So Fredrik Petersson | 2013 | World Journal of Gastroenterology2013，19，11： | 2 |
| 3 | Early Experience With Laparoscopic Radical Gastrectomy for Advanced Gastric Cancer显示文摘 | Peter M. Y. Goh Ameer Z. Khan Jimmy B. Y. So David Lomanto Wei-Keat Cheah Rajah Muthiah Anil Gandhi | 2001 | Surgical Laparoscopy, Endoscopy & Percutaneous Te2001，，2： | 1 |
| 4 | Endoscopic submucosal dissection of gastric lesions by using a Master and Slave Transluminal Endoscopic Robot (MASTER)显示文摘 | Khek-Yu Ho Soo Jay Phee Asim Shabbir Soon Chiang Low Van An Huynh Andy Prima Kencana Kai Yang Davide Lomanto Bok Yan Jimmy So Y.Y. Jennie Wong S.C. Sydney Chung | 2010 | Gastrointestinal Endoscopy2010，，3： | 1 |
| 5 | Endoscopic Tri-Modal Imaging Improves Detection of Gastric Intestinal Metaplasia Among a High-Risk Patient Population in Singapore显示文摘 | Jimmy So Andrea Rajnakova Yiong-Huak Chan Amy Tay Nilesh Shah Manuel Salto-Tellez Ming Teh Uedo Noriya | 2013 | Digestive Diseases and Sciences2013，，12： | 1 |
| 6 | Intrinsic Subtypes of Gastric Cancer, Based on Gene Expression Pattern, Predict Survival and Respond Differently to Chemotherapy显示文摘 | Iain Beehuat Tan Tatiana Ivanova Kiat Hon Lim Chee Wee Ong Niantao Deng Julian Lee Sze Huey Tan Jeanie Wu Ming Hui Lee Chia Huey Ooi Sun Young Rha Wai Keong Wong Alex Boussioutas Khay Guan Yeoh Jimmy So Wei Peng Yong Akira Tsuburaya Heike Grabsch Han Chon | 2011 | Gastroenterology2011，，2： | 1 |
| 7 | Validation of genetic variants associated with metabolic dysfunctionassociated fatty liver disease in an ethnic Chinese population显示文摘BACKGROUND Genetic factors play an important role in the pathogenesis and development of metabolic dysfunction-associated fatty liver disease(MAFLD).AIM To study the association of single nucleotide polymorphisms(SNPs),previously identified in Western populations,with the risk of MAFLD in a Singapore Chinese population and their interactions with environmental and medical risk factors.METHODS A retrospective case-control study was conducted with 72 MAFLD cases and 72 controls with no hepatic steatosis on computed tomography,magnetic resonance imaging,or controlled attenuation parameter score.Subjects were recruited from two tertiary hospitals.Genetic alleles such as NCAN,GCKR,LYPLAL1,PNPLA3,PPP1R3B,FDFT1,COL13A1,EFCAB4B,PZP,and TM6SF2 were genotyped using the TaqMan®Predesigned SNP Genotyping Assay.RESULTS Weight and body mass index(BMI)were 1.2-times higher in patients(70.6 kg,95%confidence interval[CI]:57.1-84.1 vs 60.8 kg,95%CI:48.5-73.1,P<0.001 and 26.9 kg,95%CI:23-40.8 vs 23.3 kg 95%CI:19-27.6,P<0.001 respectively).The prevalence of diabetes mellitus in patients was 40.3%and 20.8%in controls(P=0.011).Patients had higher mean triglycerides than controls(P<0.001).PNPLA3 GG was more likely to be associated with MAFLD(43.4%CC vs 69.7%GG,P=0.017,and 44.8%CG vs 69.7%GG,P=0.022).In multivariable analysis,hypertriglyceridemia(odds ratio[OR]:2.0495%CI:1.3-3.1,P=0.001),BMI(OR:1.295%CI:1.1-1.4,P<0.001)and PNPLA3 GG(OR:3.495%CI:1.3-9.2,P=0.014)were associated with MAFLD(area under the receiver operating characteristic curve of 0.823).CONCLUSION Among the Chinese population of Singapore,PNPLA3 homozygous GG allele is a strong predictor of MAFLD,whereas LYPLAL1,GCKR,FDFT1,COL13A1,PZP,and TM6SF2 are not significantly associated.Hypertriglyceridemia,high BMI,and PNPLA3 GG are independent predictors of MAFLD. | Guan Huei Lee Wah Wah Phyo Wai Mun Loo Raymond Kwok Taufique Ahmed Asim Shabbir Jimmy So Calvin Jianyi Koh Juanda Leo Hartono Mark Muthiah Kieron Lim Poh Seng Tan Yin Mei Lee Seng GeeLim Yock Young Dan | 2020 | World Journal of Hepatology2020，12，12： | 1 |
| 8 | Intrinsic Subtypes of Gastric Cancer, Based on Gene Expression Pattern, Predict Survival and Respond Differently to Chemotherapy显示文摘 | Iain Beehuat Tan Tatiana Ivanova Kiat Hon Lim Chee Wee Ong Niantao Deng Julian Lee Sze Huey Tan Jeanie Wu Ming Hui Lee Chia Huey Ooi Sun Young Rha Wai Keong Wong Alex Boussioutas Khay Guan Yeoh Jimmy So Wei Peng Yong Akira Tsuburaya Heike Grabsch Han Chon | 2011 | Gastroenterology2011，，2： | 1 |
| 9 | Intrinsic Subtypes of Gastric Cancer, Based on Gene Expression Pattern, Predict Survival and Respond Differently to Chemotherapy显示文摘 | Iain Beehuat Tan Tatiana Ivanova Kiat Hon Lim Chee Wee Ong Niantao Deng Julian Lee Sze Huey Tan Jeanie Wu Ming Hui Lee Chia Huey Ooi Sun Young Rha Wai Keong Wong Alex Boussioutas Khay Guan Yeoh Jimmy So Wei Peng Yong Akira Tsuburaya Heike Grabsch Han Chon | 2011 | Gastroenterology2011，，2： | 1 |
| 10 | Intrinsic Subtypes of Gastric Cancer, Based on Gene Expression Pattern, Predict Survival and Respond Differently to Chemotherapy显示文摘 | Iain Beehuat Tan Tatiana Ivanova Kiat Hon Lim Chee Wee Ong Niantao Deng Julian Lee Sze Huey Tan Jeanie Wu Ming Hui Lee Chia Huey Ooi Sun Young Rha Wai Keong Wong Alex Boussioutas Khay Guan Yeoh Jimmy So Wei Peng Yong Akira Tsuburaya Heike Grabsch Han Chon | 2011 | Gastroenterology2011，，2： | 1 |
| 11 | Laparoscopic appendectomy by residents: evaluating outcomes and learning curve显示文摘 | Yap Yan Lin Asim Shabbir Jimmy B. Y. So | 2010 | Surgical Endoscopy2010，，1： | 1 |
| 12 | Reduction of hospital stay and cost after the implementation of a clinical pathway for radical gastrectomy for gastric cancer显示文摘 | Jimmy B Y So Ziliang L Lim Heng-An Lin Thiow-Kong Ti | | 0，，： | 1 |
| 13 | 天安·千树显示文摘“千树”场地距上海市中心仅20分钟路程,毗邻苏州河,四通八达,也曾是工业历史的核心地带。如今,它已崛起为当代艺术的繁荣之地。天安中国投资有限公司将此地块开发,希望在融合滨水自然元素的同时,让新与旧和谐共存。规定中,新设计需要保留历史建筑的部分,并需包含住宅、酒店、零售和商业的功能。 | 托马斯·赫斯维克 Lisa Finlay Dani Rossello Diez Jimmy Hung Thomas Impiglia Leo Cheung Claudia Orsetti Dimitrije Miletic Shan Li Vichayuth Meenaphant Vincenzo D’Auria Yuxiang Cao Chris Tsui Nicolas Leuina Osbert So Philipp Nedomlel Philip Hall-Patch Kelin Yue 朱清言(摄) Noah Sheldon(摄) 无 | 2019 | 建筑实践2019，2，11： | 0 |
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