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| 1 | Effect of magnesium ions/Type I collagen promote the biological behavior of osteoblasts and its mechanism显示文摘Type I collagen(Col I)is a main component of extracellular matrix(ECM).Its safety,biocompatibility,hydrophilicity and pyrogen immunogenicity make it suitable for tissues engineering applications.Mg2t also control a myriad of cellular processes,including the bone development by enhancing the attachment and differentiation of osteoblasts and accelerating mineralization to enhance bone healing.In our studies,Mg2t bind collagen to promote the proliferation and differentiation of osteoblasts through the expression of integrins and downstream signaling pathways.In order to clarify the biological behavior effect of 10mM Mg2t/Col I coating,we performed 3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide(MTT),alkaline phosphatase(ALP),406-diamidino-2-phenylindole(DAPI),Alizarin red staining and Rhodamine B-isothiocyanate(RITC)-labeled phalloidin experiments and found that 10mM Mg2t group,Col I-coating group,10mM Mg2t/Col I-coating group,respectively,promoted the proliferation and differentiation of osteoblasts,especially 10mM Mg2t/Col I-coating group.We detected the mRNA expression of osteogenic-related genes(Runx2,ALP and OCN,OPN and BMP-2)and the protein expression of signaling pathway(integrin a2,integrin b1,FAK and ERK1/2),these results indicated that 10mM Mg2t/Col I coating play an critical role in up-regulating the MC3T3-E1 cells activity.The potential mechanisms of this specific performance may be through activating via integrin a2b1-FAK-ERK1/2 protein-coupled receptor pathway. | Xiaojing Nie Xirao Sun Chengyue Wang Jingxin Yang | 2020 | Regenerative Biomaterials2020，7，1： | 8 |
| 2 | Determination of rare earth elements in plant protoplasts by MAA显示文摘A preliminary study on the speciation of rare earth elements in plant cells has been carried out by molecular activation analysis (MAA). Mesophyll protoplasts of Brassica napus were isolated by enzymatic digestion. After being washed with isosmotic solution containing EDTA for several times, the protoplasts were purified by gradient centrifugation. Then the concentration of rare earth elements (REEs) in the protoplasts was determined by neutron activation analysis. The result shows that REEs can enter the cells of the plant. | ZHANG Zhiyong WANG Yuqi SUN Jingxin LI Fuliang CHAI Zhifang XU Lei LI Xin CAO Guoyin | 2000 | Chinese Science Bulletin2000，45，16： | 8 |
| 3 | Hd1,Ghd7,and DTH8 synergistically determine the rice heading date and yield-related agronomic traits显示文摘Heading date determines the seasonal and regional adaptation of rice(Oryza sativa L.)varieties and is mainly controlled by photoperiod sensitivity(PS).The core heading date genes Hd1,Ghd7,DTH8,and PRR37 act synergistically in regulating the PS.In this study,we systematically analyze the heading date,PS,and agronomic traits of eight homozygous lines with various combinations of Hd1,Ghd7,and DTH8 alleles in the prr37 background under long-day(LD)and short-day(SD)conditions,respectively.We find that Hd1 alone promotes heading,regardless of the day length.However,under LDs,Hd1 suppresses flowering,in coordination with functional Ghd7 or with Ghd7 and DTH8.These loci cooperate to negatively regulate the Ehd1-Hd3 a/RFT1 pathway and delay heading.Under SDs,Hd1 competes with various heading suppressors to promote heading.Therefore,the dual function of Hd1 is vital for PS.The lines carrying Hd1 alone show reduced plant height with fewer primary and secondary branches in panicles.Lines carrying Ghd7 and DTH8(with hd1)show delayed heading and improve agronomic traits.Overall,our results reveal the regulation of rice PS flowering by the core heading date genes and their effects on agronomic traits,providing valuable information for the selection of rice varieties for adaptation to different light and temperature conditions. | Kangli Sun Minghui Huang Wubei Zong Dongdong Xiao Chen Lei Yanqiu Luo Yingang Song Shengting Li Yu Hao Wanni Luo Bingqun Xu Xiaotong Guo Guangliang Wei Letian Chen Yao-Guang Liu Jingxin Guo | 2022 | Journal of Genetics and Genomics2022，49，5： | 4 |
| 4 | Hierarchical ferric-cobalt-nickel ternary oxide nanowire arrays supported on graphene fibers as high-performance electrodes for flexible asymmetric supercapacitors显示文摘基于纤维的 supercapacitors (FSC ) 是精力存储家庭的新成员。他们现在的优秀灵活性并且在小、灵活、便携的设备有有希望的应用。当保留灵活性时, FSC 的存在挑战之一正在提高他们的精力密度。我们开发了一个灵巧、划算的方法基于层次 ferric-cobalt-nickel 制作一个高度电容的积极电极第三的氧化物 nanowire arrays/graphene 纤维和一个否定电极基于导出 polyaniline 的碳 nanorods/graphene 纤维。漂亮微观结构和两个电极的优秀电气化学的表演使我们能构造 highperformance 灵活不对称的 graphene 有 1.4 V 的操作电压的基于纤维的 supercapacitor 设备,一个特定的电容直到 61.58 mF ??摔??圠敔????猯'T??????????????猯'T???????猯'T??? | Jingxin Zhao Chaowei Li Qichong Zhang Jun Zhang Xiaona Wang Juan Sun Juanjuan Wang Jixun Xie Ziyin Lin Zhuo Li Weibang Lu Conghua Lu Yagang Yao | 2018 | Nano Research2018，11，4： | 3 |
| 5 | Epithelial-mesenchymal transition status of circulating tumor cells in breast cancer and its clinical relevance显示文摘Objective:Circulating tumor cells(CTCs)play a critical role in cancer metastasis,but their prevalence and significance remain unclear.This study attempted to track the epithelial-mesenchymal transition(EMT)status of CTCs in breast cancer patients and investigate their clinical relevance.Methods:In this study,the established negFACS-IF:E/M platform was applied to isolate rare CTCs and characterize their EMT status in breast cancer.A total of 89 breast cancer patients were recruited,including stage 0–III(n=60)and late stage(n=29)cases.Results:Using the negFACS-IF:E/M platform,it was found that in human epidermal growth factor receptor 2(HER2)+patients,mesenchymal CTCs usually exhibited a high percentage of HER2+cells.Stage IV breast cancer patients had considerably more CTCs than stage 0–III patients.Among stage 0–III breast cancers,the HER2 subtype included a significantly higher percentage of mesenchymal and biphenotypic(epithelial and mesenchymal)CTCs than the luminal A or B subtypes.Among stage IV patients,CTCs were predominantly epithelial in cases with local recurrence and were more mesenchymal in cases with distant metastasis.By applying a support vector machine(SVM)algorithm,the EMT status of CTCs could distinguish between breast cancer cases with metastasis/local recurrence and those without recurrence.Conclusions:The negFACS-IF:E/M platform provides a flexible and generally acceptable method for the highly sensitive and specific detection of CTCs and their EMT traits in breast cancer.This study demonstrated that the EMT status of CTCs had high clinical relevance in breast cancer,especially in predicting the distant metastasis or local recurrence of breast cancer. | Jiaojiao Zhou Xuan Zhu Shijie Wu Jingxin Guo Kun Zhang Chunjing Xu Huihui Chen Yuxi Jin Yuting Sun Shu Zheng Yiding Chen | 2020 | Cancer Biology & Medicine2020，17，1： | 3 |
| 6 | Effect of peanut protein isolate on functional properties of chicken salt-soluble proteins from breast and thigh muscles during heat-induced gelation显示文摘 | Jingxin Sun Zhen Wu Xinglian Xu Peng Li | 2011 | Meat Science2011，，1： | 2 |
| 7 | Effect of peanutprotein isolate on functional properties of chicken salt - solubleproteins from breast and thigh muscles during heat - inducedgelation 显示文摘 | Jingxin Sun Zhen Wu Xinglian Xu | 2012 | Meat Science2012，91，： | 1 |
| 8 | Concentrations and distributions of trace and minor elements in Chinese and Canadian coals and ashes显示文摘 | Sun Jingxin R. E. Jervis | 1987 | Journal of Radioanalytical and Nuclear Chemistry Articles1987，，1： | 1 |
| 9 | Medical X-ray Coherent Scatter Images Processing based on the MRF Model显示文摘 | Liu taihui Sun junxi Liu jingxin | 2006 | Proc of SPIE2006，6026，： | 1 |
| 10 | Experimental research on adsorption/desorption for petroleum pollutants in the soil in Daqing oilfield显示文摘 | Xiaoyan LIU Yingli LI Guocheng MAO Jungang LI Chun LI Jingxin SUN Qianya ZHU | 2006 | Chinese Journal Of Geochemistry2006，25，B08： | 1 |
| 11 | REE bound DNA in natural plant显示文摘 | Yuqi Wang Ping Jiang Fanqing Guo Zhiyong Zhang Jingxin Sun Lei Xu Guoyin Cao | 1999 | Science in China Series B: Chemistry1999，，4： | 1 |
| 12 | REE bound polysaccharides in leaves of Dicranopteris dichotoma by MAA显示文摘 | Yuqi Wang Jingxin Sun Hongmin Chen Fanqing Guo Lei Xu Guoyin Cao | 1998 | Science in China Series B: Chemistry1998，，3： | 1 |
| 13 | Effect of peanut protein isolate on functional properties of chicken salt-soluble proteins from breast and thigh muscles during heat-induced gelation显示文摘 | SUN Jingxin WU Zhen LI Ping | 2012 | Meat Science2012，91，1： | 1 |
| 14 | Symmetry Feature and Construction for the 3-Band Tight Framelets with Prescribed Properties显示文摘 | Jianjun Sun Bin Huang Xiaodong Chen Lihong Cui Jingxin Zhang | 2012 | Journal of Applied Mathematics2012，，： | 1 |
| 15 | The Effect of 17 β-Estradiol on Invasion by the Ovarian Clear Cell Adenocarcinoma Cell Line ES-2 and the Molecular Mechanism Involved显示文摘 | Jingxin Ding Youji Feng Lianhuo Yin Hongyan Jin Xiaoxia Liu Liangqing Yao Yunyan Sun | 2005 | Chinese Journal of Clinical Oncology2005，2，4： | 1 |
| 16 | Research on reactiveadsorption desulfurization over NiO/Zn0-Si02 -AI2 O3 adsor-bent in a fixed-fluidized bed reactor 显示文摘 | Fan Jingxin Wang Gang Sun Yu eZ al | 2010 | Industrial Engi-neering Chemistry Research2010，49，18： | 1 |
| 17 | Effect of peanut protein isolate on functional properties of chicken salt-soluble proteins from breast and thigh muscles during heat-induced gelation显示文摘 | Jingxin Sun Zhen Wu Xinglian Xu | 2012 | Meat Science2012，91，： | 1 |
| 18 | Cyclosporine inhibits apoptosis in experimental murine xerophthalamia conjunctival epithelium显示文摘 | Jinghua Sun Jingxin Wang | 2006 | Journal of Huazhong University of Science and Technology2006，，4： | 1 |
| 19 | The analysis and forecast for fouling in water pipelines in Daqing oilfield显示文摘 | Xiaoyan LIU Qianya ZHU Jinlai FENG Gang QI Baosen ZHANG Yingli LI Jingxin SUN | 2006 | Chinese Journal Of Geochemistry2006，25，B08： | 0 |
| 20 | l_(1)-norm Based GWLP for Robust Frequency Estimation显示文摘In this work,we address the frequency estimation problem of a complex single-tone embedded in the heavy-tailed noise.With the use of the linear prediction(LP)property and l_(1)-norm minimization,a robust frequency estimator is developed.Since the proposed method employs the weighted l_(1)-norm on the LP errors,it can be regarded as an extension of the l_(1)-generalized weighted linear predictor.Computer simulations are conducted in the environment of α-stable noise,indicating the superiority of the proposed algorithm,in terms of its robust to outliers and nearly optimal estimation performance. | Yuan Chen Liangtao Duan Weize Sun Jingxin Xu | 2019 | Journal on Big Data2019，1，3： | 0 |
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