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| 1 | The Late Pleistocene activity of the eastern part of east Kunlun fault zone and its tectonic significance显示文摘The nearly EW-trending East Kunlun fault zone is the north boundary of the Bayan Har block.The activity characteristics and the position of the eastern end of its eastward extension are of great significance to probing into the dynamic mechanism of formation of the east edge of the Tibetan Plateau,and also lay the foundation for seismic risk assessment of the fault zone.The following results are obtained by analysis based on satellite image interpretation of landforms,surface rupture survey,terrace scarp deformation survey,and terrace dating data on the eastern part of the East Kunlun fault zone:(1)the Luocha segment is a Holocene active fault,where a reverse L-shape paleoearthquake surface rupture zone of about 50 km long is located;(2)the Luocha segment is characterized by left-lateral slip movement under the compression-shear condition since the later period of the Late Pleistocene,with a rate of 7.68–9.37 mm/a and a vertical slip rate of 0.7–0.9 mm/a,which are basically in accord with the activity rate of segments on its west side.The results indicate that it is a part of eastward extension of the East Kunlun fault zone;(3)the high-speed linear horizontal slip of the nearly EW-trending East Kunlun fault zone is blocked by the South China block at east,and transforms into the vertical movement of the nearly SN-NNE trending Minjiang fault zone and the Longmenshan fault zone,and the uplift of Longmenshan and Minjiang.The area where transform of the two tectonic systems occurred confines the position of the east end;(4)Luocha segment and Maqu segment constitute the'Maqu seismic gap',so,seismic risk at Maqu segment is higher than that at Luocha segment,which should attract more attention. | ZHANG JunLong REN JinWei CHEN ChangYun FU JunDong YANG PanXin XIONG RenWei HU ChaoZhong | 2014 | Science China Earth Sciences2014，57，3： | 8 |
| 2 | Xuefuzhuyu injection induces neuronal differentiation of rat bone morrow mesenchymal stem cells显示文摘The primary effective components of Xuefuzhuyu,including Rhizoma Chqanxiong,Radix Salviae Miltiorrhiae,and Radix Angelicae Sinensis,have been shown to induce the differentiation of bone marrow mesenchymal stem cells(BMMSCs) into neuronal-like cells.However,there is little available evidence on the effects of the Chinese herbal compound Xuefuzhuyu on BMMSC differentiation.The present study investigated the effects of Xuefuzhuyu on differentiation of rat BMMSCs into neuronal-like cells,and evaluated the optimal concentration for inducing differentiation.Inverted microscopy was used to observe BMMSCs induced by Xuefuzhuyu;immunocytochemistry revealed expression of the neuronal marker neuron-specific enolase surface antigen in the majority of BMMSCs following treatment with Xuefuzhuyu at concentrations of 1,3,5,and 10 g/L.A concentration of 3 g/L resulted in highest neuron-specific enolase expression.These results suggest that BMMSCs can be induced to differentiate into neuronal-like cells with Xuefuzhuyu,and 3 g/L is the optimal inductive concentration for effective differentiation. | Yin, Yanqing Chen, Bing Ke, Junlong Mo, Wei Zou, Xinhui Liang, Yuansheng | 2011 | Neural Regeneration Research2011，6，3： | 6 |
| 3 | Performance of overlapped shield tunneling through an integrated physical model tests,numerical simulations and real-time field monitoring显示文摘In this work,deformations and internal forces of an existing tunnel subjected to a closely overlapped shield tunneling are monitored and analyzed using a series of physical model experiments and numerical simulations.Effects of different excavation sequences and speeds are explicitly considered in the analysis.The results of the physical model experiments show that the bottom-up tunneling procedure is better than the top-down tunneling procedure.The incurred deformations and internal forces of the existing tunnel increase with the excavation speed and the range of influence areas also increase accordingly.For construction process control,real-time monitoring of the power tunnel is used.The monitoring processes feature full automation,adjustable frequency,real-time monitor and dynamic feedback,which are used to guide the construction to achieve micro-disturbance control.In accordance with the situation of crossing construction,a numerical study on the performance of power tunnel is carried out.Construction control measures are given for the undercrossing construction,which helps to accomplish the desired result and meet protection requirements of the existing tunnel structure.Finally,monitoring data and numerical results are compared,and the displacement and joint fracture change models in the power tunnel subject to the overlapped shield tunnel construction are analyzed. | Junlong Yang Chen Liu Qiushi Chen Xiongyao Xie | 2017 | Underground Space2017，2，1： | 3 |
| 4 | Induced regulatory T cells suppress Tel cells through TGF-β signaling to ameliorate STZ-induced type 1 diabetes mellitus显示文摘Type 1 diabetes mellitus(T1D)is a chronic autoimmune condition in which the immune system destroys insulin-producing pancreatic β cells.In addition to well-established pathogenic effector T cells,regulatory T cells(Tregs)have also been shown to be defective in T1D.Thus,an increasing number of therapeutic approaches are being developed to target Tregs.However,the role and mechanisms of TGF-β-induced Tregs(iTregs)in T1D remain poorly understood.Here,using a streptozotocin(STZ)-induced preclinical T1D mouse model,we found that iTregs could ameliorate the development of T1D and preserve β cell function.The preventive effect was associated with the inhibition of type 1 cytotoxic T(Tel)cell function and rebalancing the Treg/Tc1 cell ratio in recipients.Furthermore,we showed that the underlying mechanisms were due to the TGF-β-mediated combinatorial actions of mTOR and TCF1.In addition to the preventive role,the therapeutic effects of iTregs on the established STZ-T1D and nonobese diabetic(NOD)mouse models were tested,which revealed improved β cell function.Our findings therefore provide key new insights into the basic mechanisms involved in the therapeutic role of iTregs in T1D. | Li Zhou Xuemin He Peihong Cai Ting Li Rongdong Peng Junlong Dang Yue Li Haicheng Li Feng Huang Guojun Shi Chichu Xie Yan Lu Yanming Chen | 2021 | Cellular & Molecular Immunology2021，18，3： | 3 |
| 5 | Preseismic deformation associated with the 2014 Ms7.3 Yutian earthquake derived from GPS data显示文摘Based on analysis of the GPS data during 1999-2007,2009-2011,and 2011-2013 mainly from the Crustal Motion Observation Network of China,we obtained the GPS horizontal velocity field,the GPS strain rate field,and the profiles across the southwestern segment of the Altyn Tagh Fault zone and its adjacent regions and identified the different characteristics of horizontal crustal deformation fields and profiles during different periods. The results show that,before the February 12,2014,Ms7. 3 Yutian earthquake,the laevorotation deformation along the southwestern segment of the Altyn Tagh Fault zone increased about 3. 3 mm /a during 2011-2013,relative to that in 2009-2011,and the GPS strain rate field distributed in the southeastern segment of the Altyn Tagh Fault during 2011-2013 increased obviously. These abnormal changes may be regarded as precursors to the Ms7. 3 Yutian earthquake. | Chen Changyun Chen Fuchao Zheng Zhijiang Zhu Shuang Zhang Junlong Yang Panxin | 2014 | Geodesy and Geodynamics2014，5，2： | 3 |
| 6 | A novel adaptive lateral reentry guidance algorithm with complex distributed no-fly zones constraints显示文摘Aimed at complex distributed no-fly zones avoidance problems,a novel adaptive lateral reentry guidance algorithm is proposed.Firstly,by introducing the improved attractive and repulsive potential fields,an improved artificial potential field method is developed.Combined with the proposed judgment criterion for whether a no-fly zone has been avoided,the proposed improved artificial potential field method effectively solves the reference heading angle determination problem under the constraints of complex distributed no-fly zones.Then,based on the proposed no-fly zone’s threat quantitative evaluation method and the reference heading angle determined by the proposed improved artificial potential field method,the heading corridor is improved to increase its sensitivity to the threat changes of the no-fly zones.Finally,for satisfying the requirements of complex distributed no-fly zones avoidance,a novel guidance logic via improved heading corridor is proposed to update the reference heading corridor adaptively in real time according to the threat and constraint changes of the no-fly zones,and the bank reversal logic is employed to control the lateral motion.The simulation results for nominal and dispersed cases indicate that the proposed guidance algorithm has high robustness,stability,and applicability,and is feasible and effective to deal with the complex distributed no-fly zones avoidance problems. | Yudong HU Changsheng GAO Junlong LI Wuxing JING Wenxue CHEN | 2022 | Chinese Journal of Aeronautics2022，35，7： | 2 |
| 7 | Light-induced protein translocation by genetically encoded unnatural amino acid in Caenorhabditis elegans显示文摘Dear Editor,Living systems such as Caenorhabditis elegans are organized by interaction networks of biopolymer and small mol-ecules.The molecular engineering of specifi c targets to monitor and control these biological molecules has led to significant advances in our understand-ing of how biological systems are organ-ized,maintain themselves and disin-tegrate(Prescher and Bertozzi,2005).For instance,green fl uorescent protein(GFP)derived from jellyfi sh Aequorea Victoria helps us to accurately locate and observe proteins over long term periods.In addition,many novel LOV(light,oxy-gen,or voltage)domains such as LOV2-Jαand Vivid offer the possibility of cell-based motility management and tissue-based gene expression control(Wu et al.,2009;Wang et al.,2012). | Hao Chang Mei Han Wenming Huang Guifeng Wei Juanjuan Chen Peng R.Chen Runsheng Chen Junlong Zhang Tao Xu Pingyong Xu | 2013 | Protein & Cell2013，4，12： | 2 |
| 8 | Synthesis of novel hierarchical porous polymers with a nanowire-interconnected network structure from core-shell polymer nanoobjects显示文摘Design and fabrication of the micro/nanostructures of the network units is a critical issue for porous nanonetwork structured materials. Significant progress has been attained in construction of the network units with zero-dimensional spherical shapes.However, owing to the limitations of synthetic methods, construction of porous building blocks in one dimension featuring high aspect ratios for porous nanonetwork structured polymer(PNSP) remains largely unexplored. Here we present the successful design and preparation of PNSP with a novel type of one-dimensional network unit, i.e., microporous heterogeneous nanowire. Well-defined core-shell polymer nanoobjects prepared from a gelable block copolymer, poly(3-(triethoxysilyl)propyl methacrylate)-block-polystyrene are employed as building blocks, and facilely transformed into PNSP via hypercrosslinking of polystyrene shell. The as-prepared PNSP exhibits unique three-dimensional hierarchical nanonetwork morphologies with large surface area. These findings could provide a new avenue for fabrication of unique well-defined PNSP, and thus generate valuable breakthroughs in many applications. | yeru liang yingbo ruan junlong huang bo peng chen-yang liu ruowen fu mingqiu zhang yongming chen dingcai wu | 2017 | Science China Chemistry2017，60，8： | 2 |
| 9 | Angular Distribution of Element Contents in Tree Rings and the Environmental Information显示文摘Element contents of tree rings and soils near tree roots collected from Deodar cedar (Cedrus deodara (Roxb.) G. Don) and Masson pine (Picks massoniana lamb.) were determined to study the relationship between the angular distribution of element contents in tree rings and the environmental information. The chemical composition and properties of soils are very much complicated, which leads to the non-uniform distribution of the element contents in tree rings. The statistical multi-variable regression method was used to got the information of the tree-centered distribution of element contents in the environment (soil) (C’), C’(z, θj ), from the distribution of element contents in tree rings (C), C(Z, θi), which depends on the plane azimuth angle (θi), i. e., C=C(Z,θi), where Z is the atomic number of the element, with a satisfactory result,though this study is only a primary one. | KE SHANZHE LIU ZHENGRONG QIAN JUNLONG CHEN RUSONGI and KE XIAOKANG (Physics Department, Nanjing University, Nanjing 210095,China)(Nanjing Institute of Geogmphy and Limnology, the Chinese Academy of Sciences, Nanjing 210008, China)(Garded and Greenbelt | 1999 | Pedosphere1999，9，1： | 2 |
| 10 | Surface Rupture and Coseismic Displacement of the M_S7.1 Yushu Earthquake显示文摘On April 14,2010,a devastating earthquake measured 7.1 on the Richter scale struck Yushu county,Qinghai Province,China.Field geological investigation and remote sensing interpretation show that this earthquake generated an inverse 'L-shaped' surface rupture zone,approximately 50km long.The surface rupture zone can be divided into three segments.Between the northern and middle segments of the surface rupture,there is a 16km-long segment,where no rupture was observed.The middle and the southern segments are arranged in a left-step manner,and there are right-step en echelon ruptures developed in the stepovers.The seismogenic structure is the Yushu fault,which is dominated by strike-slip with a small amount of thrust component.The earthquake results from the differential movements between the southern Qiangtang Block and northern Bayan Har Block.The earthquake recurrence interval is 185a^108a.Along an approximately 20km-long part of the Garzê-Yushu fault,between the southern surface rupture of Yushu MS7.1 earthquake and the 1896 earthquake,there is no surface rupture,its seismic risk needs further research. | Zhang Junlong Chen Changyun Hu Chaozhong Yang Panxin Xiong Renwei Li Zhimin Ren Jinwei | 2011 | Earthquake Research in China2011，25，2： | 2 |
| 11 | Sugar transfer of nanomaterials and flexible electrodes显示文摘Nanomaterials with various dimensionalities(e.g.,nanowires,nanofilms,two-dimensional materials,and three-dimensional nanostructures)have shown great potential in the recent development of flexible electronics.Conventionally,organic solvents are inevitable while integrating nanomaterials onto flexible substrates,where polymer mediator-assisted transfer techniques are involved.This often damages the flexible substrate and thus hamper the large-scale application of nanomaterials.Here we report a method using watersoluble sugar as a mediator to facilely transfer nanomaterials onto rigid or flexible substrates.This method requires no organic solvent during transfer.More importantly,the morphology and properties of transferred nanomaterials,such as shape,microstructure,resistivity,and transmittance are well preserved on the target substrate.We believe that this universal and rapid transfer method can greatly advance the applications of nanomaterials in the field of flexible devices and beyond. | Tianzeng Hong Tianze Shen Junlong Yang Yichen Sun Jianming Zhang Haiyang Pan Ying Hong Yan Wang Shuo Chen Yue Zhao Chuan Fei Guo | 2020 | International Journal of Smart and Nano Materials2020，11，1： | 1 |
| 12 | Liquiritin potentiate neurite outgrowth induced by nerve growth factor in PC12 cells显示文摘 | CHEN Zhengai WANG Junlong LIU Ruiting | 2009 | Cytoteehnology2009，60，13： | 1 |
| 13 | Association of three SNPs in interleukin-28B with graft hepatic dysfunction after liver transplantation in Chinese Han population显示文摘 | Jie Chen Yi Li Lanlan Wang Yang Fu Yun Liao Junlong Zhang | 2012 | Gene2012，，1： | 1 |
| 14 | Characterizing airflow through fabric air dispersion system using a porous media model 显示文摘 | Fujiang Chen Huanxin Chen Junlong Xie | 2011 | Ener- gy and Buildings2011，43，23： | 1 |
| 15 | Air distribution in room ventilated by fabric air dispersion system 显示文摘 | Fujiang Chen Huanxin Chen Junlong Xie | 2011 | Building and Environ- ment2011，46，11： | 1 |
| 16 | Study of micro-trichome (mict) reveals novel connections between transcriptional regulation of multicellular trichome development and specific metabolism in cucumber显示文摘Trichomes that cover the epidermis of aerial plant organs play multiple roles in plant protection.Compared with a unicellular trichome in model plants,the development mechanism of the multicellular trichome is largely unclear.Notably,variations in trichome development are often accompanied by defects in the biosynthesis of cuticle and secondary metabolites;however,major questions about the interactions between developmental differences in trichomes and defects in metabolic pathways remain unanswered.Here,we characterized the glabrous mutant mict/csgl1/cstbh via combined metabolomic and transcriptomic analyses to extend our limited knowledge regarding multicellular trichome development and metabolism in cucumber.Mict was found to be explicitly expressed within trichome cells.Transcriptomic analysis indicated that genes involved in flavonoid and cuticle metabolism are significantly downregulated in mict mutants.Further metabolomic analysis confirmed that flavonoids,lipids,and cuticle compositions are dramatically altered in mict mutants.Additional studies revealed that Mict regulates flavonoid,lipid,and cuticle biosynthesis by likely directly binding to downstream functional genes,such as CsTT4,CsFLS1,CsCER26,and CsMYB36.These findings suggest that specific metabolic pathways(e.g.,flavonoids and cuticle components)are co-regulated by Mict and provide insights into transcriptional regulation mechanisms of multicellular trichome development and its specific metabolism in cucumber. | Jian Pan Leyu Zhang Guanqun Chen Haifan Wen Yue Chen Hui Du Junlong Zhao Huanle He Hongli Lian Huiming Chen Jianxin Shi Run Cai Gang Wang Junsong Pan | 2021 | Horticulture Research2021，8，1： | 1 |
| 17 | Air distribution in room ventilated by fabric air dispersion system显示文摘 | Chen Fujiang Chen Huanxin Xie Junlong | 2011 | Building and Environment2011，46，11： | 1 |
| 18 | User abnormal behavior analysis based on neural network clustering显示文摘It is the premise of accessing and controlling cloud environment to establish the mutual trust relationship between users and clouds. How to identify the credible degree of the user identity and behavior becomes the core problem? This paper proposes a user abnormal behavior analysis method based on neural network clustering to resolve the problems of over-fitting and flooding the feature information, which exists in the process of traditional clustering analysis and calculating similarity. Firstly, singular value decomposition(SVD) is applied to reduce dimension and de-noise for massive data, where map-reduce parallel processing is used to accelerate the computation speed, and neural network model is used for softening points. Secondly, information entropy is added to hidden layer of neural network model to calculate the weight of each attribute. Finally, weight factor is used to calculate the similarity to make the cluster more accuracy. For the problem of analyzing the mobile cloud user behaviors, the experimental results show that the scheme has higher detection speed(DS) and clustering accuracy than traditional schemes. The proposed method is more suitable for the mobile cloud environment. | Zheng Ruijuan Chen Jing Zhang Mingchuan Zhu Junlong Wu Qingtao | 2016 | The Journal of China Universities of Posts and Telecommunications2016，23，3： | 0 |
| 19 | Numerical modeling and performance evaluation of passive convergence-permeable reactive barrier(PC-PRB)显示文摘The passive convergence-permeable reactive barrier(PC-PRB)was proposed to address the limitations of traditional PRB configurations.To evaluate the hydraulic and pollutant removal performance of the PC-PRB system,we developed a simulation code named PRB-Trans.This code uses the two-dimensional(2D)finite element method to simulate groundwater flow and solute transport.Case studies demonstrate that PC-PRB technology is more efficient and cost-effective than continuous permeable reactive barrier(C-PRB)in treating the same contaminated plume.Implementation of PC-PRB technology results in a 33.3%and 72.7%reduction in PRB length(L_(PRB))and height(H_(PRB)),respectively,while increasing 2D horizontal and 2D vertical pollutant treatment efficiencies of PRB by 87.8%and 266.8%,respectively.In addition,the PC-PRB technology has the ability to homogenize the pollutant concentration and pollutant flux through the PRB system,which can mitigate the problems arising from uneven distribution of pollutants in the C-PRB to some extent.The L_(PRB)required for PC-PRB decreases as the water pipe length(L_(p))increases,while the H_(PRB)required initially decreases and then increases with increasing L_(p).The effect of passive well height(Hw)on H_(PRB)is not as significant as that of L_(p)on H_(PRB).Overall,PC-PRB presents a promising and advantageous PRB configuration in the effective treatment of various types of contaminated plumes. | Kaixuan Zheng Dong Xie Yiqi Tan Zhenjiang Zhuo Tan Chen Hongtao Wang Ying Yuan Junlong Huang Tianwei Sun Fangming Xu Yuecen Dong Ximing Liang | 2023 | Frontiers of Environmental Science & Engineering2023，17，11： | 0 |
| 20 | Characteristics of Late Quaternary Activity of the Gadê Segment in the Madoi-Gadê Fault Zone显示文摘Madoi-Gadê fault is an active fault in the Bayan Har block.According to field investigation,there is an earthquake surface rupture fairly well preserved on the Gadê segment of the Madoi-Gadê fault zone.The length of the rupture is approximately 50km,with a general strike of NW.The maximum horizontal sinistral displacement is about 7.6m and the maximum vertical displacement is about 4m.A large number of earthquake traces are to be found along the rupture zone,and the phenomena on the surface rupture are also various.Field investigation and analysis on the geological and geomorphological phenomena show that the formation age of the surface rupture is relatively young.A series of linear arranged,triangular facets,fault scarps,fault springs,dislocated gullies,twisted mountain ridges,sag-ponds,dislocated ridges,etc.exist along the fault.Based on the analysis of field investigation and the data available,we believe that the surface rupture is due to a strong earthquake in the history of this area.And it is inferred that the Madoi-Gadê fault within the Bayan Har block has been highly active since Late Quaternary and may still be active nowadays. | Xiong Renwei Ren Jinwei Zhang Junlong Yang Panxin Li Zhimin Hu Chaozhong Chen Changyun | 2011 | Earthquake Research in China2011，25，2： | 0 |
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