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| 1 | Benefits of nucleos(t)ide analog treatments for hepatitis B virus-related cirrhosis显示文摘Chronic hepatitis B infection induces progressive liver disease. Before nucleos(t)ide analogs(NUCs) became established as a safe and effective treatment for hepatitis B,it was difficult to suppress the activity of the hepatitis B virus(HBV). Currently,many patients withhepatitis or cirrhosis associated with HBV are treated with NUCs for an extended period of time,and the effects,benefits,and limitations of these treatments have been apparent. This article reviews HBV-related cirrhosis,its natural course and survival,histological improvement after NUC treatments,treatment effects for decompensated cirrhosis,the incidence of hepatocellular carcinoma(HCC) after NUC treatments,and the efficacy of NUC treatments before and after the treatment of patients for HBV-related HCC. Of particular interest are the histological improvements,including regression of fibrosis,that have been achieved with NUC treatments. Liver function of patients with decompensated cirrhosis has significantly improved regardless of the type of NUC applied,and treatment with NUCs has reduced the incidence of HCC in cirrhotic patients. However,cirrhosis remains the strongest risk factor for HCC occurrence following NUC treatments,and the long-term cumulative incidence of HCC after NUC treatments remains high. When recurrence does occur,it is important to reconsider the treatment modality according to the degree of improved liver function that was achieved. | Koichi Honda Masataka Seike Kazunari Murakami | 2015 | World Journal of Hepatology2015，7，22： | 9 |
| 2 | Streaming induced by ultrasonic vibration in a water vessel 显示文摘 | Shinfuku Nomura Koichi Murakami Yuaichi Sasaki | 2000 | Jpn J Appl Phys2000，39，： | 1 |
| 3 | 猪隐秘杆菌型出血性坏死性脾炎显示文摘六月龄去势公猪表现昏睡、食欲不振、站立困难。尸检发现脾脏边缘呈多重出血灶。从脾脏、肾脏、肌肉和肝脏中分离出革兰氏阳性杆菌,对分离株(TO16177)的16S rDNA基因序列比较分析发现,其可能与未发表过的隐秘杆菌属HJ57-14E菌株(登记号:gi18873551)(比较675bp个碱基,相似性达99.7%)为同一个属。脾脏组织切片的组织学检查发现呈广泛性坏死和炎症,其中革兰氏阳性杆菌显而易见。肝脏中可见多病灶的坏死斑。免疫组织化学检测发现,分离株与抗化脓性隐秘杆菌属(Arcanobacterium pyogenes)和内氏放线菌(Actinomyces naeslundii)的多克隆抗体具有交叉反应,且与后者的交叉反应更强烈。相似的反应也见于扁桃体的化脓灶中分离株,偶尔也见于脾脏和淋巴结中的分离株。本研究结果表明,这种未公开发布的隐秘杆菌属的细菌会引起生长肥育猪多器官功能衰竭,而后继发急性出血性坏死性脾炎。 | 任彬(译) 常飞(校) Takemi OHBA Tomoyuki Shibahara Hideki Kobayashi Masanori Kubo Ariko Takaahima ShigenoriImai Satoshi Murakami Koichi Kadota | 2007 | 国外畜牧学(猪与禽)2007，，4： | 1 |
| 4 | Clinical proteomics identified ATP-dependent RNA helicase DDX39 as a novel biomarker to predict poor prognosis of patients with gastrointestinal stromal tumor显示文摘 | Kazutaka Kikuta Daisuke Kubota Tsuyoshi Saito Hajime Orita Akihiko Yoshida Hitoshi Tsuda Yoshiyuki Suehara Hitoshi Katai Yasuhiro Shimada Yoshiaki Toyama Koichi Sato Takashi Yao Kazuo Kaneko Yasuo Beppu Yasufumi Murakami Akira Kawai Tadashi Kondo | 2011 | Journal of Proteomics2011，，4： | 1 |
| 5 | Diagnosis of cardiac sarcoidosis and evaluation of the effects of steroid therapy by gadolinium-DTPA–enhanced magnetic resonance imaging显示文摘 | Toshio Shimada Kazue Shimada Takeshi Sakane Koichi Ochiai Hironori Tsukihashi Motonari Fukui Shin-ichi Inoue Harumi Katoh Yo Murakami Yutaka Ishibashi Riruke Maruyama | 2001 | The American Journal of Medicine2001，，： | 1 |
| 6 | Further investigation of the modifying effect of various chemopreventive agents on apoptosis and cell proliferation in human colon cancer cells显示文摘 | Qiao Zheng Yoshinobu Hirose Naoki Yoshimi Akira Murakami Koichi Koshimizu Hajime Ohigashi Keiko Sakata Yuji Matsumoto Yoshikatsu Sayama Hideki Mori | 2002 | Journal of Cancer Research and Clinical Oncology2002，，10： | 1 |
| 7 | Immunological Impact of Neoadjuvant Chemoradiotherapy in Patients with Borderline Resectable Pancreatic Ductal Adenocarcinoma显示文摘 | Yuki Homma Koichi Taniguchi Takashi Murakami Kazuya Nakagawa Masatoshi Nakazawa Ryusei Matsuyama Ryutaro Mori Kazuhisa Takeda Michio Ueda Yasushi Ichikawa Kuniya Tanaka Itaru Endo | 2014 | Annals of Surgical Oncology2014，，2： | 1 |
| 8 | Bubble effects on the solution IR drop in a vertical electrolyzer under free and forced convection 显示文摘 | Fumio Hine Koichi Murakami | 1980 | Journal of The Electrochemical Society1980，127，2： | 1 |
| 9 | An anatomical study of short hepatic veins, with special reference to delineation of the caudate lobe for hanging maneuver of the liver without the usual mobilization显示文摘 | Toshio J. Sato Ichiro Hirai Gen Murakami Tetsuhiro Kanamura Fumitake Hata Koichi Hirata | 2002 | Journal of Hepato - Biliary - Pancreatic Surgery2002，，1： | 1 |
| 10 | Conformal radiation therapy for portal vein tumor thrombosis of hepatocellular carcinoma显示文摘 | Ryo Toya Ryuji Murakami Yuji Baba Ryuichi Nishimura Shoji Morishita Osamu Ikeda Koichi Kawanaka Toru Beppu Shinichi Sugiyama Takashi Sakamoto Yasuyuki Yamashita Natsuo Oya | 2007 | Radiotherapy and Oncology2007，，3： | 1 |
| 11 | Risk factors for deterioration of long-term liver function after radiofrequency ablation therapy显示文摘AIM:To identify factors that influence long-term liver function following radiofrequency ablation(RFA)in patients with viral hepatitis-related hepatocellular carcinoma.METHODS:A total of 123 patients with hepatitis B virus-or hepatitis C virus-related hepatocellular carcinoma(HCC)(n=12 and n=111,respectively)were enrolled.Cumulative rates of worsening Child-Pugh(CP)scores(defined as a 2-point increase)were examined.RESULTS:CP score worsening was confirmed in 22patients over a mean follow-up period of 43.8±26.3mo.Multivariate analysis identified CP class,platelet count,and aspartate aminotransferase levels as significant predictors of a worsening CP score(P=0.000,P=0.011 and P=0.024,respectively).In contrast,repeated RFA was not identified as a risk factor for liver function deterioration.CONCLUSION:Long-term liver function following RFA was dependent on liver functional reserve,the degreeof fibrosis present,and the activity of the hepatitis condition for this cohort.Therefore,in order to maintain liver function for an extended period following RFA,suppression of viral hepatitis activity is important even after the treatment of HCC. | Koichi Honda Masataka Seike Junya Oribe Mizuki Endo Mie Arakawa Hiroki Syo Masao Iwao Masanori Tokoro Junko Nishimura Tetsu Mori Tsutomu Yamashita Satoshi Fukuchi Toyokichi Muro Kazunari Murakami | 2016 | World Journal of Hepatology2016，8，13： | 1 |
| 12 | Continuous EGFR-TKI administration following radiotherapy for non-small cell lung cancer patients with isolated CNS failure显示文摘 | Takehito Shukuya Toshiaki Takahashi Tateaki Naito Rieko Kaira Akira Ono Yukiko Nakamura Asuka Tsuya Hirotsugu Kenmotsu Haruyasu Murakami Hideyuki Harada Koichi Mitsuya Masahiro Endo Yoko Nakasu Kazuhisa Takahashi Nobuyuki Yamamoto | 2011 | Lung Cancer2011，，3： | 1 |
| 13 | Screening for the In Vitro Anti-tumor-promoting Activities of Edible Plants from Malaysia显示文摘 | Akira MURAKAMI Abdul Manaf Ali Kamaruddin MAT-SALLEH Koichi KOSHIMIZU Hajime OHIGASHI | 2000 | Bioscience, Biotechnology, and Biochemistry2000，，1： | 1 |
| 14 | Ignition Characteristics of Hydrocarbon Fuels by Plasma Torch in Supersonic Flow显示文摘 | Koichi Murakami Aya Nishikawa Kenichi Takita | 2003 | 12th AIAA International Space Planes and Hypersonic Sys- tems and Technologies AIAA 20032003，12，： | 1 |
| 15 | Ig- nition Characteristics of Methane and Hydrogen Using a Plasma Torch in Supersonic Flow显示文摘 | Tomoaki Kitagawa Atsushi Moriwaki Koichi Murakami | 2003 | Journal of Propulsion and Power2003，5，： | 1 |
| 16 | CT appearance of radiation injury of the lung and clinical symptoms after stereotactic body radiation therapy (SBRT) for lung cancers: Are patients with pulmonary emphysema also candidates for SBRT for lung cancers?显示文摘 | Tomoki Kimura Kanji Matsuura Yuji Murakami Yasutoshi Hashimoto Masahiro Kenjo Yuko Kaneyasu Koichi Wadasaki Yutaka Hirokawa Katsuhide Ito Motoomi Okawa | 2006 | International Journal of Radiation Oncology Biology Physics2006，，2： | 1 |
| 17 | Hemangiopericytomatous meningioma metastasized to the liver: Report of a case and review of the literature显示文摘 | Tetsuya Kaneko Akio Harada Koichi Isshiki Hiroya Murakami Akimasa Nakao Toshiaki Nonami Motoyoshi Yano Shinichi Kakumu Hiroshi Takagi | 1993 | Surgery Today1993，，7： | 1 |
| 18 | An Advanced Oscillation Mixing Method for Improving the Cooling Uniformity in Quenching显示文摘In quenching, the cooling uniformity is most important to diminish distortion occurring on work pieces. As a trial to accomplish uniform cooling, therefore, there exist various mixing methods of a quenchant and the quenchant circulation with an external pump has so far been the well accepted mixing method. However, this study proposes an advanced oscillation mixing method that can improve more the cooling uniformity in quenching. The proposed method includes a stirrer in oscillating motion, so that the simultaneous oscillating and mixing movements of the stirrer are considered to provide effectively the uniform cooling characteristics for the quenchant. In comparison with the case of the circulation pump mixing, the investigation using the oscillation mixing method has demonstrated the following two experimental facts: (1) the short vapor blanket stage caused by the quick breakage of the oil vapor blanket and (2) the reduced variation of the quenching distortion. | Hiroyuki Hoshino Hiromitsu Murakami Hideo Yokota Satoshi Suda Hideki Tsuge Koichi Terasaka Toshiaki Wakabayashi | 2004 | 材料热处理学报2004，25，5： | 0 |
| 19 | 内燃动车能耗计算系统的开发显示文摘目前全球变暖的形势要求有严格的措施来解决所涉及的问题。例如,要求铁路运营商们采取以各种降低能耗的方法为基础的节能措施。为此,日本铁道技术研究所开发了一种新的能够计算内燃动车能耗的系统。该系统使用可用来计算列车在运行中的燃料消耗量和二氧化碳排放量的软件。本文简要介绍了该系统的结构、功能以及装车试验情况。 | Koichi MURAKAMI 何春 | 2010 | 国外内燃机车2010，，3： | 0 |
| 20 | Identification of telomere maintenance gene variations related to lung adenocarcinoma risk by genome-wide association and whole genome sequencing analyses显示文摘Dear editor,Lung carcinoma is responsible for the highest fatal-ity rate among cancer-related deaths globally,with lung adenocarcinoma(LADC)emerging as the prevailing sub-type. | Kouya Shiraishi Atsushi Takahashi Yukihide Momozawa Yataro Daigo Syuzo Kaneko Takahisa Kawaguchi Hideo Kunitoh Shingo Matsumoto Hidehito Horinouchi Akiteru Goto Takayuki Honda Kimihiro Shimizu Masahiro Torasawa Daisuke Takayanagi Motonobu Saito Akira Saito Yuichiro Ohe Shun-ichi Watanabe Koichi Goto Masahiro Tsuboi Katsuya Tsuchihara Sadaaki Takata Tomomi Aoi Atsushi Takano Masashi Kobayashi Yohei Miyagi Kazumi Tanaka Hiroyuki Suzuki Daichi Maeda Takumi Yamaura Maiko Matsuda Yoko Shimada Takaaki Mizuno Hiromi Sakamoto Teruhiko Yoshida Yasushi Goto Tatsuya Yoshida Taiki Yamaji Makoto Sonobe Shinichi Toyooka Kazue Yoneda Katsuhiro Masago Fumihiro Tanaka Megumi Hara Nobuo Fuse Satoshi S.Nishizuka Noriko Motoi Norie Sawada Yuichiro Nishida Kazuki Kumada Kenji Takeuchi Kozo Tanno Yasushi Yatabe Kuniko Sunami Tomoyuki Hishida Yasunari Miyazaki Hidemi Ito Mitsuhiro Amemiya Hirohiko Totsuka Haruhiko Nakayama Tomoyuki Yokose Kazuyoshi Ishigaki Toshiteru Nagashima Yoichi Ohtaki Kazuhiro Imai Ken Takasawa Yoshihiro Minamiya Kazuma Kobayashi Kenichi Okubo Kenji Wakai Atsushi Shimizu Masayuki Yamamoto Motoki Iwasaki Koichi Matsuda Johji Inazawa Yuichi Shiraishi Hiroyoshi Nishikawa Yoshinori Murakami Michiaki Kubo Fumihiko Matsuda Yoichiro Kamatani Ryuji Hamamoto Keitaro Matsuo Takashi Kohno | 2024 | Cancer Communications2024，44，2： | 0 |
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