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| 1 | Modular growth and clonal propagation of Hippophae rhamnoides subsp, sinensis in response to irrigation intensity显示文摘A multipurpose clone plant species,Hippophae rhamniodes has the capacity for indefinite longevity,although under successive drought stress it may often decline or die across large areas.Field trials were conducted over 2 years to examine the effects of varied irrigation intensities on modular growth and clonal propagation in a semi-arid area.Irrigation levels included a control,as well as two,four and six times the volume of water that was typically received via local annual average precipitation.Irrigation intensity significantly influenced clonal propagation capacity(number of daughter ramets),aboveground modular growth(height,base diameter,and crown width),belowground modular growth included root nodule dry weight,stretching capacity of lateral roots(length of the longest lateral roots,and diameter of firstgrade lateral roots),and branching intensity of lateral roots(number of lateral roots bifurcation grade,number of firstgrade lateral roots).The modular growth and the density of daughter ramets were small under non-irrigation or low irrigation,and became larger with increased irrigation intensity.Beyond a certain threshold,however,further increases in irrigation intensity resulted in a reversion to the development.The optimal irrigation intensities for growth and propagation were 3.48–5.29 times the volume of nominal local annual average precipitation.There were effects of irrigation intensities on the positive significant correlations between aboveground and belowground modular growths,and on clonal propagation capacities.Under various water treatments,H.rhamnoides may adapt to the environment through the regulation of growth and propagation.We concluded that water shortages act to weaken the growth and propagation of H.rhamniodes plantations. | Zilin Cao Tianjiang Li Genqian Li Chunhong Liu Haiyin Gao Guanghui Dai Zhiyong Xiao Sunling Li | 2016 | Journal of Forestry Research2016，27，5： | 14 |
| 2 | Synthesis and characterization of boron nitride sponges as a novel support for metal nanoparticles显示文摘This paper describes a simple synthetic route for the synthesis of hexagonal boron nitride (h-BN) powders with high specific surface area, in which BBr3, NH4Cl and Al powders are used as starting materials. The structure and composition of the powders were characterized by electron diffraction, Fourier transformation infrared spectroscopy and X-ray photoelectron spectroscopy in the selected area. X-ray diffraction shows wide peaks of crystalline h-BN with the particle size on the nanometer scale, and transmission electron microscopy reveals that the products have a novel spongy morphology. Silver nanoparticles loaded h-BN sponges were prepared via a one-step synthesis method. Different reaction conditions for the formation of h-BN sponges were also investigated. | ZHENG MingTao LIU YingLiang GU YunLe XU ZiLin | 2008 | Science China Chemistry2008，51，3： | 7 |
| 3 | Bisphenol A in combination with TNF-a selectively induces Th2 cell-promoting dendritic cells in vitro with an estrogen-like activity显示文摘Bisphenol A(BPA)is a monomer used in manufacturing a wide range of chemical products,including epoxy resins and polycarbonate.BPA,an important endocrine disrupting chemical that exerts estrogen-like activities,is detectable at nanomolar levels in human serum worldwide.The pregnancy associated doses of 17b-estradiol(E2)plus tumor-necrosis factor-a(TNF-a)induce distorted maturation of human dendritic cells(DCs)that result in an increased capacity to induce T helper(Th)2 responses.The current study demonstrated that the presence of BPA during DC maturation influences the function of human DCs,thereby polarizing the subsequent Th response.In the presence of TNF-a,BPA treatment enhanced the expression of CC chemokine ligand 1(CCL1)in DCs.In addition,DCs exposed to BPA/TNF-a produced higher levels of IL-10 relative to those of IL-12p70 on CD40 ligation,and preferentially induced Th2 deviation.BPA exerts the same effect with E2 at the same dose(0.01–0.1 mM)with regard to DC-mediated Th2 polarization.These findings imply that DCs exposed to BPA will provide one of the initial signals driving the development and perpetuation of Th2-dominated immune response in allergic reactions. | Hongchuan Guo Tianyi Liu Yasushi Uemura Shunchang Jiao Deqing Wang Zilin Lin Yayoi Narita Motoharu Suzuki Narumi Hirosawa Yasuko Ichihara Osamu Ishihara Hirosato Kikuchi Yasushi Sakamoto Satoru Senju Qiuhang Zhang Feng Ling | 2010 | Cellular & Molecular Immunology2010，7，3： | 6 |
| 4 | The heterogeneity of islet autoantibodies and the progression of islet failure in type 1 diabetic patients显示文摘Type 1 diabetes mellitus is heterogeneous in many facets. The patients suffered from type 1 diabetes present several levels of islet function as well as variable number and type of islet-specific autoantibodies. This study was to investigate prevalence and heterogeneity of the islet autoantibodies and clinical phenotypes of type 1 diabetes mellitus; and also discussed the process of islet failure and its risk factors in Chinese type 1 diabetic patients. A total of 1,291 type 1 diabetic patients were enrolled in this study. Demographic information was collected. Laboratory tests including mixed-meal tolerance test, human leukocyte antigen alleles, hemoglobin A1 c, lipids, thyroid function and islet autoantibodies were conducted. The frequency of islet-specific autoantibody in newly diagnosed T1 DM patients(duration shorter than half year) was 73% in East China. According to binary logistic regressions, autoantibody positivity, longer duration and lower Body Mass Index were the risk factors of islet failure. As the disease developed, autoantibodies against glutamic acid decarboxylase declined as well as the other two autoantibodies against zinc transporter 8 and islet antigen 2. The decrease of autoantibodies was positively correlated with aggressive beta cell destruction. Autoantibodies can facilitate the identification of classic T1 DM from other subtypes and predict the progression of islet failure. As there were obvious heterogeneity in autoantibodies and clinical manifestation in different phenotypes of the disease, we should take more factors into consideration when identifying type 1 diabetes mellitus. | Jin Liu Lingling Bian Li Ji Yang Chen Heng Chen Yong Gu Bingqin Ma Wei Gu Xinyu Xu Yun Shi Jian Wang Dalong Zhu Zilin Sun Jianhua Ma Hui Jin Xing Shi Heng Miao Bing Xin Yan Zhu Zhenwen Zhang Ruifang Bu Lan Xu Guangde Shi Wei Tang Wei Li Dongmei Zhou Jun Liang Xingbo Cheng Bimin Shi Jixiang Dong Ji Hu Chen Fang Shao Zhong Weinan Yu Weiping Lu Chenguang Wu Li Qian Jiancheng Yu Jialin Gao Xiaoqiang Fei Qingqing Zhang Xueqin Wang Shiwei Cui Jinluo Cheng Ning Xu Guofeng Wang Guoqing Han Chunrong Xu Yun Xie Minmin An Wei Zhang Zhixiao Wang Yun Cai Qi Fu Yu Fu Shuai Zheng Fan Yang Qingfang Hu Hao Dai Yu Jin Zheng Zhang Kuanfeng Xu Yifan Li Jie Shen Hongwen Zhou Wei He Xuqin Zheng Xiao Han Liping Yu Jinxiong She Mei Zhang Tao Yang | 2016 | Science China(Life Sciences)2016，59，9： | 5 |
| 5 | Tomato SlPUB24 enhances resistance to Xanthomonas euvesicatoria pv. perforans race T3显示文摘Solanum lycopersicum var.cerasiforme accession PI 114490 has broad-spectrum resistance to bacterial spot caused by several species of Xanthomonas.Resistance is quantitatively inherited,and a common quantitative trait locus QTL-11B on chromosome 11 has been identified previously.In this study,the SlPub24 gene was characterized in QTL-11B.SlPub24 in PI 114490 was upregulated by infection with X.euvesicatoria pv.perforans race T3,but its transcription was low in the susceptible line OH 88119 whether or not it was infected by the pathogen.The differential expression of SlPub24 between PI 114490 and OH 88119 was due to great sequence variation in the promoter region.The promoter of SlPub24 in OH 88119 had very low activity and did not respond to pathogen infection.Transgenic lines of OH 88119 overexpressing SlPub24 isolated from PI 114490 showed significantly enhanced resistance,while mutants of Slpub24 generated by CRISPR/Cas9 editing showed more susceptibility to race T3 and to other races.The mutants also showed spontaneous cell death in leaves.The expression of the salicylic acid(SA)pathway gene phenylalanine ammonia-lyase(PAL)and signaling-related genes pathogenesis-related(PR1)and nonexpresser of PR1(NPR1)were influenced by SlPub24.The content of SA in tomato plants was consistent with the level of SlPub24 expression.Furthermore,SlPUB24 interacted with the cell wall protein SlCWP and could regulate the degradation of SlCWP.The expression levels of SlCWP and SlCWINV1,a cell wall invertase gene,showed opposite patterns during pathogen infection.The activity of SlCWINV1 was lower in mutants than in PI 114490.The results are discussed in terms of the roles of the abovementioned genes,and a potential model for SlPUB24-mediated resistance to bacterial spot is proposed. | Xin Liu Ge Meng Mengrui Wang Zilin Qian Yaxian Zhang Wencai Yang | 2021 | Horticulture Research2021，8，1： | 4 |
| 6 | Multi-objective scheduling of relief logistics based on swarm intelligence algorithms and spatio-temporal traffic flow显示文摘Emergency supplies scheduling needs to consider the state of the demanders,and reasonably scheduling and resource allocation are the heart of efficient rescue.Taking rescue time,scheduling cost and demanders’satisfac-tion as goals,in this paper,an emergency supplies scheduling model based on multi-objective optimization was proposed to provide a wealth of decision-making information.Then four multi-objective optimization algorithms are employed to obtain the optimal set of scheduling models.In addition,we design the minimum time cost model and the shortest route cost model by considering the change of the road network status.The extensive simulation experiments are conducted on a real urban traffic dataset.The experimental results show that the two cost models can serve different scheduling needs and provide efficient scheduling for emergency supplies. | Zhiming Ding Zilin Zhao Detian Liu Yang Cao | 2021 | Journal of Safety Science and Resilience2021，2，4： | 3 |
| 7 | Bacterioplankton production in dilution zone of the Changjiang (Yangtze) Estuary显示文摘The bacterioplankton production and bacterioplankton abundance were surveyed in dilution zone of the Changjiang Estuary and a mesocosm experimental device for enriched phosphate experiment and oil contaminated experiment was placed in the waters nearby Luhua Island during October 1997 and May 1998. The results showed that the average bacterioplankton production in spring was higher than that in autumn, the production at the surface water was higher than that at the bottom in the surveyed area; the higher values appeared in the middle of the area. The results from mesocosm experiment with adding phosphate and oil contaminated showed that the bacterioplankton production increased rising trend day by day during the experiment period. | Liu Zilin 1,2 , Koshikawa Hiroshi 3, Ning Xiuren 1,2 , Shi Junxian 2, Cai Yuming 1,21.KeyLaboratoryofSubmarineGeosciences,StateOceanicAdministration,China2.SecondInstituteofOceanography,StateOceanicAdministration,Hangzhou310012,China3.Nationa | 2001 | Acta Oceanologica Sinica2001，20，1： | 3 |
| 8 | Shenkang injection improves coagulation in patients with chronic kidney disease: a systematic review and Meta-analysis显示文摘OBJECTIVE: To investigate the effect of Shenkang injection(SKI) on chronic kidney disease(CKD).METHODS: Seven databases including Cochrane Central Register of Controlled Trials, PubMed, EMBASE, MEDLINE, China National Knowledge Infrastructure, Wanfang Database, and CQVIP from their inception to March 2018 were searched. Only randomized controlled trials that evaluated conventional treatment and conventional treatment with SKI in CKD patients were investigated. Outcomes such as fibrinogen(FIB), D-dimer, prothrombin time(PT), activated partial thromboplastin time(APTT), and the side effects of SKI were analyzed using Revman 5.3 software. The quality of the studies was assessed using the Cochrane Collaboration’s Risk of Bias tool and the quality of evidence was assessed using GRADEpro.RESULTS: Four randomized controlled trials were investigated in our analysis, and these studies were of moderate quality. For FIB and D-dimer, SKI had a superior effect compared with the control group(mean difference(MD)=-1.23, 95% confidence interval(CI):-1.46,-0.99, P < 0.01;MD =-0.36, 95%CI:-0.51,-0.21, P < 0.01, respectively)SKI increased APTT and PT compared with the control(MD = 7.34, 95% CI: 3.05, 11.62, P < 0.01;MD = 3.40,95% CI: 2.2, 4.61, P < 0.01, respectively). In the four studies, there were no side effects that were related to SKI.CONCLUSION: SKI may be effective in improving coagulation in patients with CKD without obvious adverse reactions. However, more well-designed studies are required to confirm the findings. | Song Zilin Qin Tianyu Pan Yajing Hua Qian Wu Lili Liu Tonghua | 2019 | Journal of Traditional Chinese Medicine2019，39，4： | 3 |
| 9 | A Self-supported Graphene/Carbon Nanotube Hollow Fiber for Integrated Energy Conversion and Storage显示文摘Wearable fiber-shaped integrated energy conversion and storage devices have attracted increasing attention,but it remains a big challenge to achieve a common fiber electrode for both energy conversion and storage with high performance.Here,we grow aligned carbon nanotubes(CNTs)array on continuous graphene(G)tube,and their seamlessly connected structure provides the obtained G/CNTs composite fiber with a unique self-supported hollow structure.Taking advantage of the hollow structure,other active materials(e.g.,polyaniline,PANI)could be easily functionalized on both inner and outer surfaces of the tube,and the obtained G/CNTs/PANI composite hollow fibers achieve a high mass loading(90%)of PANI.The G/CNTs/PANI composite hollow fibers can not only be used for high-performance fiber-shaped supercapacitor with large specific capacitance of 472 mF cm^-2,but also can replace platinum wire to build fiber-shaped dye-sensitized solar cell(DSSC)with a high power conversion efficiency of 4.20%.As desired,the integrated device of DSSC and supercapacitor with the G/CNTs/PANI composite hollow fiber used as the common electrode exhibits a total power conversion and storage efficiency as high as 2.1%.Furthermore,the self-supported G/CNTs hollow fiber could be further functionalized with other active materials for building other flexible and wearable electronics. | Kai Liu Zilin Chen Tian Lv Yao Yao Ning Li Huili Li Tao Chen | 2020 | Nano-Micro Letters2020，12，5： | 3 |
| 10 | Super Na^(+)Half/Full Batteries and Ultrafast Na+Diffusion Kinetics of Cobalt-Nickel Selenide from Assembling Co_(0.5)Ni_(0.5)Se_(2)@NC Nanosheets into Cross-Stacked Architecture显示文摘Explorati on of adva need an ode materials for sodium-i on batteries(SIBs)is still a big challe nge due to the large radius of sodium.In this work,the hierarchical architectures assembled from N-doped carbon-coated Co_(0.5)Ni_(0.5)Se_(2)(Co_(0.5)Ni_(0.5)Se_(2)@NC)nanoparticles encapsulated into cross-stacked nano sheets have been successfully prepared from the cobalt-nickel bin ary-metal organic frameworks(CoNi-MOF)by two steps of the solid-state sele nizati on and carb on coating processes.Imports ntly,the resulta nt hierarchical Co0.5Nio:5Se2@NC architecture can achieve a satisfactory electrochemical performance,maintaining a high-rate capacity of 330 mA-h-g^(-1)1 at 3 A·g^(-1) and a stable cyclability of 100 cycles without obvious capacity decay at 0.2 A·g^(-1).The design of distinct superstructure can not only be applied to other electrode materials but also boost the forward development of energy storage systems. | Zhiyong Li Zilin Peng Rui Sun Zhaoxia Qin Xinlong Liu Caihong Wang Haosen Fan Shengjun Lu | 2021 | Chinese Journal of Chemistry2021，39，9： | 3 |
| 11 | A modified similitude analysis method for the electro-mechanical performances of a parallel manipulator to solve the control period mismatch problem显示文摘Due to the discrete feature and performance limitation of the numerical controller,the control period sometimes cannot meet the constraints of the scaled model in similitude analysis,which brings the control period mismatch problem.The traditional similitude analysis methods are not able to solve this problem since the controller is treated as continuous system in these methods.This paper proposes a modified similitude analysis method to solve the control period mismatch problem,and the electro-mechanical performances of a 2-DOF parallel manipulator is predicted.Based on the model of dynamic and control system,most of the similitude laws are derived by taking the controller as continuous system.Then the transfer function of the controller in discrete form is established,and the similitude law related to control period is derived to figure out the cause of mismatch problem.The modified method,named long period equivalent,is proposed to solve the mismatch problem by using the least square method and superposition principles.Finally,the scaled model of the parallel manipulator is determined based on the modified similitude analysis method. | WU Jun SONG YuYao LIU ZiLin LI GuoFa | 2022 | Science China(Technological Sciences)2022，65，3： | 3 |
| 12 | Reassessment of the Distribution of Mantle CO_(2) in the Bohai Sea,China:The Perspective from the Source and Pathway System显示文摘Research on the distribution of mantle CO_(2)should involve comprehensive analysis from CO_(2)source to accumulation.The crust-mantle pathway system is the key controlling factor of the distribution of mantle CO_(2),but has received little attention.The pathway system and controlling factors of CO_(2)distribution in the Bohai Sea are analyzed using data on fault styles and information on the mantle and lithosphere.The relation between volcanic rocks and the distribution of mantle CO_(2)is reassessed using age data for CO_(2)accumulations.The distribution of mantle CO_(2)is controlled by uplift of the asthenosphere and upper mantle,magma conduits in the mantle and fault systems in the crust.Uplifted regions of the asthenosphere are accumulation areas for CO_(2).The area with uplift of the Moho exhibits accumulation of mantle CO_(2)at depth.CO_(2)was mainly derived from vertical migration through the upper mantle and lower crust.The fault style in the upper crust controls the distance of horizontal migration and the locations of CO_(2)concentrations.The distribution of mantle CO_(2)and volcanic rocks are not the same,but both probably followed the same pathways sometimes.Mantle CO_(2)in the Bohai Sea is concentrated in the Bozhong sag and the surrounding area,particularly in a trap that formed before 5.1 Ma and is connected to crustal faults(the Bozhang faults)and lithospheric faults(the Tanlu faults). | TANG Huafeng GUO Tianchan WU Keqiang LIU Zilin XU Jianyong LU Baoliang WANG Pujun | 2022 | Acta Geologica Sinica(English Edition)2022，96，1： | 2 |
| 13 | Anti-fatigue activity of Brassica rapa L.extract and correlation among biochemical changes in forced swimming mice显示文摘Brassica rapa L.is an edible and medical plant in China used for treating various diseases,especially in the Tibet region.In this study,the chemical constituents of Brassica rapa L.extract(BE)was clarified by UHPLC-MS and anti-fatigue ability of BE was assessed through the behavior test and weight-loaded forced swimming test in mice.Then we determined several biochemical parameters related to fatigue to explore possible reasons.Results indicate that BE could significantly enhance exercise performance in mice,and there was a significant improvement in both grip-strength and the time on rota-rods.Meanwhile,BE showed significant anti-fatigue effects by decreasing the blood lactic acid(BLA),blood urea nitrogen(BUN),and creatine kinase(CK)levels and increasing the lactate dehydrogenase(LDH)and malondialdehyde(MDA)levels.Increases in superoxide dismutase(SOD)and glutathione peroxidase(GSH-Px)were observed and reactive oxygen species(ROS)levels was regulated.Liver and muscle glycogen levels and adenosine triphosphate(ATP)levels were also significantly increased.Pearson correlation analysis indicates that fatigue-related indexes including metabolites and energy-related indexes were significantly correlated with antioxidant levels.In conclusion,BE possesses remarkable anti-fatigue activity,thereby shows great potential for improving exercise performance and alleviating physical fatigue and can be considered as a functional food supplement for further development. | Zilin Li Hongkang Zhu Hanyi Hua Chang Liu Yuliang Cheng Yahui Guo Peng Du He Qian | 2022 | Food Bioscience2022，47，3： | 2 |
| 14 | Recent advances in nonlinear optics for bio‐imaging applications显示文摘Nonlinear optics,which is a subject for studying the interaction between intense light and materials,has great impact on various research fields.Since many structures in biological tissues exhibit strong nonlinear optical effects,nonlinear optics has been widely applied in biomedical studies.Especially in the aspect of bio-imaging,nonlinear optical techniques can provide rapid,label-free and chemically specific imaging of biological samples,which enable the investigation of biological processes and analysis of samples beyond other microscopy techniques.In this review,we focus on the introduction of nonlinear optical processes and their applications in bio-imaging as well as the recent advances in this filed.Our perspective of this field is also presented. | Silu Zhang Liwei Liu Sheng Ren Zilin Li Yihua Zhao Zhigang Yang Rui Hu Junle Qu | 2020 | Opto-Electronic Advances2020，3，10： | 2 |
| 15 | The size-fractionated chlorophyll a and primary productivity in the Bering Sea during the summer of 2003显示文摘Investigations of chlorophyll a and primary productivity were carried out in the Bering Sea along the BR line and the BS line during the Second Chinese National Arctic Research Expedition in the summer of 2003. The results showed that the surface chlorophyll a concentrations were 0.199~1.170 μg/dm3, and the average value was 0.723 μg/dm3 on the BR line. For the BS line, the surface chlorophyll a concentrations were 0.519~4.644 μg/dm3 (average 1.605 μg/dm3) and 0.568~14.968 μg/dm3 (average 5.311 μg/dm3) during the early and late summer, respectively. The average value in the late summer was much higher than that in the early summer. The high values (more than 4.0 μg/dm3) occurred at stations of the BS line in the southern Bering Strait. The chlorophyll a concentrations in the subsurface layer were higher than those in the surface layer. The results of the size-fractionated chlorophyll a showed that the contribution of the picoplankton to total chlorophyll a was the predominance at the early summer and the contribution of the netplankton was the predominance at the late summer. The carbon potential primary productivities varied between 0.471 and 1.147 mg/(m3·h) on the BR line, with average rates of 0.728 mg/(m3·h). The primary productivities on the BS line were much higher than those of the BR line, ranging from 1.227 mg/(m3·h) at the early summer to 19.046 mg/(m3·h) at the late summer. The results of the size-fractionated primary productivity showed that the contribution of the nanoplankton to total productivity was the predominance at the early summer and the contribution of the netplankton was predominance at the late summer. The assimilation number of photosynthesis was 0.45~2.80 mg/(mg·h) in the surveyed stations. | LIU Zilin CHEN Jianfang CHEN Zhongyuan ZHANG Tao ZHANG Haisheng | 2005 | Acta Oceanologica Sinica2005，24，6： | 1 |
| 16 | Solutions to the functional equation I(x, y) = I(x, I(x,y)) for three types of fuzzy implications derived from uninorms 显示文摘 | Xie Aifang Liu Huawen Qin Feng Zeng Zilin | 2012 | Information Sciences2012，186，： | 1 |
| 17 | Standing stock of phytoplankton and primary productivity in Penaeus orientalis larval multiplication releasing area of the Xiangshan Bay显示文摘The standing stock of phytoplankton (phy. ) and primary productivity (pp) in the Xiangshan Bay were observed in 1992. The results showed higher biological parameters in the bay. The average chlorophyll a (chl a) concentration was (3. 50 5. 93 ) mg/m3 and the primary productivity (444. 5 871. 0) mg/(m2 d). The distribution of chl a and productivity showed distinct spatial and temporal patterns in the bay. The continent influence was Obvious at the top of the bay, lower seawater exchange and higher stability led to higher standing stock of phytoplankton and productivity. At the bay mouth, seawater exchanged continuously with adjacent waters by rapid currents, resulting in fast and unstable exchange and lower standing stock of phytoplankton and primary productivity. The seasonal characters of those parameters were pronounced, in the sequence of spring, summer, autumn and winter. The results of size--fractionated showed that the average contribution of the nano--and picoplankton (< 20pm) to total chl a and productivity were 75 % and 87%, respectively, indicating their importance in phytoplankton community biomass and productivity of the Xiangshan Bay. | Liu Zilin Cai Yuming Shi Junxiang Ning Xiuren (1. Second Institute of Oceanography, State Oceanic Administration, Hangzhou 310012, China) | 2000 | Acta Oceanologica Sinica2000，19，1： | 1 |
| 18 | Triple-functional bone adhesive with enhanced internal fixation,bacteriostasis and osteoinductive properties for open fracture repair显示文摘At present,effective fixation and anti-infection implant materials represent the mainstay for the treatment of open fractures.However,external fixation can cause nail tract infections and is ineffective for fixing small fracture fragments.Moreover,closed reduction and internal fixation during the early stage of injury can lead to potential bone infection,conducive to bone nonunion and delayed healing.Herein,we designed a bone adhesive with anti-infection,osteogenic and bone adhesion fixation properties to promote reduction and fixation of open fractures and subsequent soft tissue repair.It was prepared by the reaction of gelatin(Gel)and oxidized starch(OS)with vancomycin(VAN)-loaded mesoporous bioactive glass nanoparticles(MBGNs)covalently cross-linked with Schiff bases.Characterization and adhesion experiments were conducted to validate the successful preparation of the Gel-OS/VAN@MBGNs(GOVM-gel)adhesive.Meanwhile,in vitro cell experiments demonstrated its good antibacterial effects with the ability to stimulate bone marrow mesenchymal stem cell(BMSCs)proliferation,upregulate the expression of alkaline phosphatase(ALP)and osteogenic proteins(RunX2 and OPN)and enhance the deposition of calcium nodules.Additionally,we established a rat skull fracture model and a subcutaneous infection model.The histological analysis showed that bone adhesive enhanced osteogenesis,and in vivo experiments demonstrated that the number of inflammatory cells and bacteria was significantly reduced.Overall,the adhesive could promote early reduction of fractures and antibacterial and osteogenic effects,providing the foothold for treatment of this patient population. | Yusheng Yang Shenghui Su Shencai Liu Weilu Liu Qinfeng Yang Liangjie Tian Zilin Tan Lei Fan Bin Yu Jian Wang Yanjun Hu | 2023 | Bioactive Materials2023，，7： | 1 |
| 19 | Interannual Variations of Phytoplankton, Zooplankton and Chlorophyll a in the Arctic Seas and Their Relations to ENSO and AO显示文摘To study effects of variations in climate-marine environment in the Arctic Ocean on ecology,based on the actual and reestablished data by biomarkers of algae in sediment in 1997,1999,2003,2008,and 2010,the interannual and spatial variations of phytoplankton,zooplankton and chlorophyll a concentration in the Chukchi Sea and the Bering Sea as well as their relations to El Nino-Southern Oscillation( ENSO) and Arctic Oscillation( AO) were analyzed. The results show that there were spatial and temporal anomalies in the phytoplankton community structure reestablished by biomarkers of algae in the Chukchi Sea and the Bering Sea in 1999 and 2010. The total content of biomarkers( brassicasterol,dinosterol,C37 alkenones and chlesterol) in sediment collected in 2010 was far lower than that in 1999,but brassicasterol was dominant in the two years,that is,diatom was dominant,which was consistent with the actual structure and distribution of phytoplankton community in 1999 and 2010; there were great changes in the dominant species of plankton in the two seas in 1999 and 2010,which could be regarded as the ecological response of the North Pole under the background of global warming. Chlorophyll a concentration in the water of the Bering Sea was 0. 720 μg/dm^3 at 0 m and 0. 765μg/dm^3 at 10 m in 1997 and 0. 723 μg/dm^3 at 0 m and 0. 731 μg/dm^3 at 10 m in 2003,and the concentration was very close to each other,which was affected by El Ni1 o and the negative phase of AO. It was 0. 395 μg/dm^3 at 0 m in 1999 and 0. 399 μg/dm^3 at 0 m and 0. 357 μg/dm^3 at 10 m in 2008,which was influenced by La Ni1 a and the positive phase of AO. The phases and intensity of AO and ENSO had various effects on the quantity and dominant species of phytoplankton and zooplankton in the Chukchi Sea and the Bering Sea. During the period of AO with positive or negative phase and El Ni1o( in 1997 and 2003),their combination was favorable to the growth of phytoplankton and zooplankton,while the combination of negative phase of AO and La Nina( in 2010) had adverse effects on the growth of phytoplankton. The combination of AO with positive phase and strong La Nina( in 1999 and 2008) had small effects on phytoplankton community. | Zhang Haisheng Chen Jianfang Han Zhengbing Ji Zhongqiang Xu Xudan Han Xibing Liu Zilin Peter, H.-U Vetter Walter | 2017 | Meteorological and Environmental Research2017，8，2： | 1 |
| 20 | Protective effects of hyperoside against human umbilical vein endothelial cell damage induced by hydrogen peroxide 显示文摘 | LI Zilin LIU Jincheng HU Jing | 2012 | J Ethnopharmacolo2012，139，2： | 1 |
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