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| 1 | A Novel QTL qTGW3 Encodes the GSK3/ SHAGGY-Like Kinase OsGSK5/OsSK41 that Interacts with OsARF4 to Negatively Regulate Grain Size and Weight in Rice显示文摘谷物尺寸和形状在米饭是谷物重量和产量的重要决定因素。这里,我们报导一个新主要量的特点在米饭的地点(QTL ) , qTGW3,那种控制谷物尺寸和重量。这个地点, qTGW3,编码 OsSK41 (也作为 OsGSK5 知道) , GLYCOGEN SYNTHASE KINASE 3/SHAGGY-like 家庭的一个成员。带 OsSK41 的 loss-of-function 等位基因的瑞斯 near-isogenic 线增加了谷物长度和重量。我们证明那 OsSK41 交往与并且 phosphorylates 植物生长素反应因素 4 (OsARF4 ) 。有 OsARF4 的 OsSK41 的合作表示在米饭原物增加 OsARF4 的累积。OsARF4 的功能的损失导致更大的米饭谷物。定序 RNA 分析建议 OsARF4 和 OsSK41 镇压下游的基因的一个普通集合的表示, ? 包括一些植物生长素应答的基因,在米饭谷物开发期间。在 qTGW3 的 OsSK41 的 loss-of-function 形式代表没被指向的基因编辑或 QTL 节节上升广泛地在 OsSK41 功能的米饭 breeding.?Suppression 利用了的稀罕等位基因提高米饭谷物尺寸和重量。因此,我们的学习在米饭谷物开发揭示 OsSK41 的重要角色 ?? 并且在另外的谷物庄稼在米饭并且也许为谷物产量的基因改进提供新候选人基因。 | Zejun Hu Sun-Jie Lu Mei-Jing Wang Haohua He Le Sun Hongru Wang Xue-Huan Liu Ling Jiang Jing-Liang sun Xiaoyun Xin Wei Kong Chengcai Chu Hong-Wei Xue Jinshui Yang Xiaojin Luo Jian-Xiang Liu | 2018 | Molecular Plant2018，11，5： | 47 |
| 2 | Blind reconnaissance of the pseudo-random sequence in DS/SS signal with negative SNR显示文摘This paper introduces a new theory and algorithm that can be used in blind detection of the carrier wave signal and the pseudo-random sequence of the direct sequence spread spectrum (DS/SS) signal with negative SNR. First, without any a priori knowledge of the DS/SS signal, the carrier wave signal can be detected from DS/SS signal with negative SNR by using stochastic differential equations and energy detection method. Based on this, the pseudo-random sequence can also be blindly detected in DS/SS signal with negative SNR by reducing noise of the nonlinear signal and the algorithm of wavelet multiscale decomposition algorithm. Finally, the computer simulation shows that we can detect the carrier wave signal with SNR=-27 dB and the pseudo-random sequence under error code ratio 10-4 with SNR =-10 dB. | HUANG XianGao HUANG Wei WANG Chao LU ZeJun HU YanHua | 2007 | Science in China(Series F)2007，50，3： | 6 |
| 3 | Nasal delivery of broadly neutralizing antibodies protects mice from lethal challenge with SARS-CoV-2 delta and omicron variants显示文摘Multiple new variants of severe acute respiratory syndrome coronavirus 2(SARS-Co V-2)have constantly emerged,as the delta and omicron variants,which have developed resistance to currently gained neutralizing antibodies.This highlights a critical need to discover new therapeutic agents to overcome the variants mutations.Despite the availability of vaccines against coronavirus disease 2019(COVID-19),the use of broadly neutralizing antibodies has been considered as an alternative way for the prevention or treatment of SARS-Co V-2 variants infection.Here,we show that the nasal delivery of two previously characterized broadly neutralizing antibodies(F61 and H121)protected K18-h ACE2 mice against lethal challenge with SARS-Co V-2 variants.The broadly protective efficacy of the F61 or F61/F121 cocktail antibodies was evaluated by lethal challenge with the wild strain(WIV04)and multiple variants,including beta(B.1.351),delta(B.1.617.2),and omicron(B.1.1.529)at 200or 1000 TCID_(50),and the minimum antibody administration doses(5-1.25 mg/kg body weight)were also evaluated with delta and omicron challenge.Fully prophylactic protections were found in all challenged groups with both F61 and F61/H121 combination at the administration dose of 20 mg/kg body weight,and corresponding mice lung viral RNA showed negative,with almost all alveolar septa and cavities remaining normal.Furthermore,low-dose antibody treatment induced significant prophylactic protection against lethal challenge with delta and omicron variants,whereas the F61/H121 combination showed excellent results against omicron infection.Our findings indicated the potential use of broadly neutralizing monoclonal antibodies as prophylactic and therapeutic agent for protection of current emerged SARS-Co V-2 variants infection. | Jia Lu Qiangling Yin Rongjuan Pei Qiu Zhang Yuanyuan Qu Yongbing Pan Lina Sun Ding Gao Cuiqin Liang Jingwen Yang Wei Wu Jiandong Li Zongqiang Cui Zejun Wang Xinguo Li Dexin Li Shiwen Wang Kai Duan Wuxiang Guan Mifang Liang Xiaoming Yang | 2022 | Virologica Sinica2022，37，2： | 4 |
| 4 | Deciphering active biocompatibility of iron oxide nanoparticles from their intrinsic antagonism显示文摘 | Lu Wang Zejun Wang Xiaoming Li Yi Zhang Min Yin Jiang Li Haiyun Song Jiye Shi Daishun Ling Lihua Wang Nan Chen Chunhai Fan | 2018 | Nano Research2018，11，5： | 2 |
| 5 | The ethylene-, jasmonate-, abscisic acid- and NaCl-responsive tomato transcription factor JERF1 modulates expression of GCC box-containing genes and salt tolerance in tobacco显示文摘 | Haiwen Zhang Zejun Huang Bingyan Xie Qi Chen Xin Tian Xiulin Zhang Hongbo Zhang Xiangyang Lu Dafang Huang Rongfeng Huang | 2004 | Planta2004，，2： | 1 |
| 6 | A New Method to Derived one Set of Scaling Criteria for Reac- tor Natural Circulation at Single-Phase and Two-Phase Conditions 显示文摘 | LU Donghua XIAO Zejun CHEN Bingde | 2010 | Nuclear Engineering and Design2010，240，11： | 1 |
| 7 | OBV(obscure vein),a C_(2)H_(2)zinc finger transcription factor,positively regulates chloroplast development and bundle sheath extension formation in tomato(Solanum lycopersicum)leaf veins显示文摘Leaf veins play an important role in plant growth and development,and the bundle sheath(BS)is believed to greatly improve the photosynthetic efficiency of C_(4) plants.The OBV mutation in tomato(Solanum lycopersicum)results in dark veins and has been used widely in processing tomato varieties.However,physiological performance has difficulty explaining fitness in production.In this study,we confirmed that this mutation was caused by both the increased chlorophyll content and the absence of bundle sheath extension(BSE)in the veins.Using genome-wide association analysis and map-based cloning,we revealed that OBV encoded a C_(2)H_(2) L domain class transcription factor.It was localized in the nucleus and presented cell type-specific gene expression in the leaf veins.Furthermore,we verified the gene function by generating CRISPR/Cas9 knockout and overexpression mutants of the tomato gene.RNA sequencing analysis revealed that OBV was involved in regulating chloroplast development and photosynthesis,which greatly supported the change in chlorophyll content by mutation.Taken together,these findings demonstrated that OBV affected the growth and development of tomato by regulating chloroplast development in leaf veins.This study also provides a solid foundation to further decipher the mechanism of BSEs and to understand the evolution of photosynthesis in land plants. | Jinghua Lu Chunyang Pan Xin Li Zejun Huang Jinshuai Shu Xiaoxuan Wang Xiaoxiao Lu Feng Pan Junling Hu Hui Zhang Wenyue Su Min Zhang Yongchen Du Lei Liu Yanmei Guo Junming Li | 2021 | Horticulture Research2021，8，1： | 1 |
| 8 | The ethylene-, jasmonate-, abscisic acid- and NaCl-responsive tomato transcription factor JERF1 modulates expression of GCC box-containing genes and salt tolerance in tobacco显示文摘 | Haiwen Zhang Zejun Huang Bingyan Xie Qi Chen Xin Tian Xiulin Zhang Hongbo Zhang Xiangyang Lu Dafang Huang Rongfeng Huang | 2004 | Planta2004，，2： | 1 |
| 9 | The ethylene-, jasmonate-, abscisic acid- and NaCl-responsive tomato transcription factor JERF1 modulates expression of GCC box-containing genes and salt tolerance in tobacco显示文摘 | Haiwen Zhang Zejun Huang Bingyan Xie Qi Chen Xin Tian Xiulin Zhang Hongbo Zhang Xiangyang Lu Dafang Huang Rongfeng Huang | 2004 | Planta2004，，2： | 1 |
| 10 | The ethylene-, jasmonate-, abscisic acid- and NaCl-responsive tomato transcription factor JERF1 modulates expression of GCC box-containing genes and salt tolerance in tobacco显示文摘 | Haiwen Zhang Zejun Huang Bingyan Xie Qi Chen Xin Tian Xiulin Zhang Hongbo Zhang Xiangyang Lu Dafang Huang Rongfeng Huang | | 0，2004，： | 1 |
| 11 | Hardware Circuit Implementation and Performance Analysis of Three-Slot NP-CSMA显示文摘The development of wireless communication technology has become increasingly important in the communications industry.How to allocate limited channel resources reasonably and reliably to each competing user is a problem that the access protocol of the MAC(Multiple Access Control)layer needs to solve.As an important way of random access,NP-CSMA(Non Persistent Carrier Sense Multiple Access)has a higher network throughput rate when the arrival rate is higher.This paper analyzes and improves the implemented NP-CSMA model,and obtains a three-slot NP-CSMA model.The mathematical tool MATLAB is used to analyze the network throughput,delay and energy efficiency of the model,and compare several random multiple access protocols adheres to the network throughput,they are NP-CSMA,Three-slot NP-CSMA,1-persistent CSMA,P-persistent CSMA,and concludes that the three-slot NP-CSMA is significantly letter than several other multiple access protocols.Finally,using Quartus to design the three-slot NP-CSMA circuit,the statistical value of the circuit system is compared with the theoretical value of the model,and the error is less than 0.01,which proves that the system is reasonable in design and can be applied to wireless communication networks. | Xu Lu Hongwei Ding Zejun Han Zhijun Yang Liqing Wang Liyong Bao | 2019 | Computer Modeling in Engineering & Sciences2019，，6： | 0 |
| 12 | PtCu-SnO_(2)nanocomposites for ultrasensitive and rapid ultra-low formaldehyde sensing显示文摘SnO 2 nanospheres with diameters of 30∼50 nm and Pt x Cu 1-x bimetallic nanoparticles with sizes of approxi-mately 10 nm were synthesized via hydrothermal and solvothermal methods,respectively.The Pt x Cu 1-x bimetal-lic nanoparticles were impregnated on the surface of the SnO 2 spheres to form Pt x Cu 1-x-SnO 2 nanocomposites.By varying the atomic ratios between platinum(Pt)and copper(Cu),we found that Pt 0.75 Cu 0.25-SnO 2,with a large specific surface area of 89.21 m 2/g,enabled the selective and accurate detection of low-concentration formalde-hyde compared to other metal-deposited samples and pure SnO 2.The response value of Pt 0.75 Cu 0.25-SnO 2 to 500×10−9 formaldehyde was approximately 20 at an operating temperature of 160◦C with an extremely high-speed response(15 s).The porous structures with large specific surface areas,as well as the improved catalytic effects of Pt 0.75 Cu 0.25,comprehensively contributed to the enhanced sensing performance towards formaldehyde. | Zejun Han Yunxiang Tang Guixia Lu Yuan Qi Hao Wu Zhengyi Yang Hecheng Han Xue Zhang Lili Wu Zhou Wang Jiurong Liu Fenglong Wang | 2022 | ChemPhysMater2022，1，3： | 0 |
| 13 | Catalytically active atomically thin cuprate with periodic Cu single sites显示文摘Rational design and synthesis of catalytically active two-dimensional(2D)materials with an abundance of atomically precise active sites in their basal planes remains a great challenge.Here,we report a ligand exchange strategy to exfoliate bulk[Cu_(4)(OH)_(6)][O_(3)S(CH_(2))_4SO_(3)]cuprate crystals into atomically thin 2D cuprate layers([Cu_(2)(OH)_(3)]^(+)).The basal plane of 2D cuprate layers contains periodic arrays of accessible unsaturated Cu(Ⅱ)single sites(2D-CuSSs),which are found to promote efficient oxidative Chan-Lam coupling.Our me chanistic studies reveal that the reactions proceed via coordinatively unsaturated CuO_4(Ⅰ)single sites with the formation of Cu(Ⅰ)species in the rate-limiting step,as corroborated by both operando experimental and theoretical studies.The robust stability of 2D-CuSSs in both batch and continuous flow reactions,coupled with their recyclability and good performance in complex molecule derivatization,render 2D-CuSSs attractive catalyst candidates for broad utility in fine chemical synthesis. | Huimin Yang Shibo Xi Na Guo Mu Wang Lingmei Liu Pin Lyu Xiaolong Yu Jing Li Haomin Xu Xiao Hai Zejun Li Xinzhe Li Tao Sun Xiaoxu Zhao Yu Han Wei Yu Jie Wu Chun Zhang Honghan Fei Ming Joo Koh Jiong Lu | 2023 | National Science Review2023，10，1： | 0 |
| 14 | Novel 2D CaCl crystals with metallicity, room-temperature ferromagnetism, heterojunction, piezoelectricity-like property and monovalent calcium ions显示文摘Under ambient conditions,the only known valence state of calcium ions is+2,and the corresponding crystals with calcium ions are insulating and nonferromagnetic.Here,using cryo-electron microscopy,we report direct observation of two-dimensional(2D)CaCl crystals on reduced graphene oxide(rGO)membranes,in which the calcium ions are only monovalent(i.e.+1).Remarkably,metallic rather than insulating properties are displayed by those CaCl crystals.More interestingly,room-temperature ferromagnetism,graphene-CaCl heterojunction,coexistence of piezoelectricity-like property and metallicity,as well as the distinct hydrogen storage and release capability of the CaCl crystals in rGO membranes are experimentally demonstrated.We note that such CaCl crystals are obtained by simply incubating rGO membranes in salt solutions below the saturated concentration,under ambient conditions.Theoretical studies suggest that the formation of those abnormal crystals is attributed to the strong cation-πinteractions of the Ca cations with the aromatic rings in the graphene surfaces.The findings highlight the realistic potential applications of such abnormal CaCl material with unusual electronic properties in designing novel transistors and magnetic devices,hydrogen storage,catalyzers,high-performance conducting electrodes and sensors,with a size down to atomic scale. | Lei Zhang Guosheng Shi Bingquan Peng Pengfei Gao Liang Chen Ni Zhong Liuhua Mu Lijuan Zhang Peng Zhang Lu Gou Yimin Zhao Shanshan Liang Jie Jiang Zejun Zhang Hongtao Ren Xiaoling Lei Ruobing Yi Yinwei Qiu Yufeng Zhang Xing Liu Minghong Wu Long Yan Chungang Duan Shengli Zhang Haiping Fang | 2021 | National Science Review2021，8，7： | 0 |
| 15 | Valproic acid therapy decreases serum 25-hydroxyvitamin D level in female infants and toddlers with epilepsy-a pilot longitudinal study显示文摘To evaluate if valproic acid(VPA)therapy is associated with vitamin D deficiency among infants and toddlers with epilepsy,a cross-sectional clinical study was conducted in 25 children with epilepsy taking VPA.Blood levels of calcium,phosphorus,alkaline phosphatase,and 25-hydroxy vitamin D[25(OH)D]and plasma VPA level were measured at 1-to 3-month intervals.At the initial and final measurements,vitamin D deficiency or insufficiency was recognized in 8(32%)and 12(42%),respectively.In girls,a decreasing trend in serum25(OH)D levels(P<0.05)was observed.Polytherapy had a significant negative effect on the longitudinal change of 25(OH)D(P<0.05)in girls.In conclusion,our study indicates that a high proportion of girls after VPA therapy had hypovitaminosis D. | Jinchun Qiu Hongli Guo Ling Li Zeyue Xu Zejun Xu Xia Jing Yahui Hu Xiaoyi Wen Feng Chen Xiaopeng Lu | 2021 | The Journal of Biomedical Research2021，35，1： | 0 |
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