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| 1 | Helicity dependent directional surface plasmon polariton excitation using a metasurface with interfacial phase discontinuity显示文摘Surface plasmon polaritons(SPPs)have been widely exploited in various scientific communities,ranging from physics,chemistry to biology,due to the strong confinement of light to the metal surface.For many applications,it is important that the free space photon can be coupled to SPPs in a controllable manner.In this Letter,we apply the concept of interfacial phase discontinuity for circularly polarizations on a metasurface to the design of a novel type of polarization-dependent SPP unidirectional excitation at normal incidence.Selective unidirectional excitation of SPPs along opposite directions is experimentally demonstrated at optical frequencies by simply switching the helicity of the incident light.This approach,in conjunction with dynamic polarization modulation techniques,opens gateway towards integrated plasmonic circuits with electrically reconfigurable functionalities. | Lingling Huang Xianzhong Chen Benfeng Bai Qiaofeng Tan Guofan Jin Thomas Zentgraf Shuang Zhang | 2013 | Light(Science & Applications)2013，2，1： | 31 |
| 2 | COVID-19 Outbreak Caused by Contaminated Packaging of Imported Cold-Chain Products—Liaoning Province,China,July 2020显示文摘Summary What is known about this topic?Few major outbreaks of coronavirus disease 2019(COVID-19)have occurred in China after major nonpharmaceutical interventions and vaccines have been deployed and implemented.However,sporadic outbreaks that had high possibility to be linked to cold chain products were reported in several cities of China..What is added by this report?In July 2020,a COVID-19 outbreak occurred in Dalian,China.The investigations of this outbreak strongly suggested that the infection source was from COVID-19 virus-contaminated packaging of frozen seafood during inbound unloading personnel contact.What are the implications for public health practice?Virus contaminated paper surfaces could maintain infectivity for at least 17–24 days at-25℃.Exposure to COVID-19 virus-contaminated surfaces is a potential route for introducing the virus to a susceptible population.Countries with no domestic transmission of COVID-19 should consider introducing prevention strategies for both inbound travellers and imported goods.Several measures to prevent the introduction of the virus via cold-chain goods can be implemented. | Huilai Ma1 Jianqun Zhang Ji Wang Ying Qin Cao Chen Yang Song Liang Wang Jun Meng Lingling Mao Fengqin Li Ning Li Jian Cai Yong Zhang Dayan Wang Yunting Xia Hong Wang Shaofeng Jiang Xiang Zhao Peihua Niu Wenjie Tan Tao Ma Yecheng Yao Naiying Mao Zhen Zhu Tianjiao Ji Qian Yang Baoying Huang Li Zhao Jianxing Yu Li Bai Shuangli Zhu Dongyan Wang Yan Zhang Yingwei Sun Mingchun Luan Yanhai Wang Haibo Sun Shihong Yang Zhijian Bo Xiang Ren Zhongjie Li George Fu Gao Wei Yao Wenqing Yao Zijian Feng Wenbo Xu | 2021 | China CDC weekly2021，3，21： | 16 |
| 3 | Polyphenylene sulfide based anion exchange fiber:Synthesis,characterization and adsorption of Cr(VI)显示文摘A fibrous strong base anion exchanger(QAPPS) was prepared for the first time via chloromethylation and quaternary amination reaction of polyphenylene sulfide fiber(PPS),and its physical-chemical structure and adsorption behavior for Cr(VI) were characterized by FTIR,Energy Dispersive Spectrometry,TG-DTG,elemental analysis and batch adsorptive technique,respectively.The novel fibrous adsorbent could effectively adsorb Cr(VI) over the pH range 1-12,the maximum adsorption capacity was 166.39 mg/g at pH 3.5,and the adsorption behavior could be described well by Langmuir isotherm equation model.The adsorption kinetics was studied using pseudo first-order and pseudo second-order models,and the t 1/2 and equilibrium adsorption time were 5 and 20 min respectively when initial Cr(VI) concentration was 100 mg/L.The saturated fibers could be regenerated rapidly by a mixed solution of 0.5 mol/L NaOH and 0.5 mol/L NaCl,and the adsorption capacity was well maintained after six adsorption-desorption cycles. | Jiajia Huang Xin Zhang Lingling Bai Siguo Yuan | 2012 | Journal of Environmental Sciences2012，24，8： | 16 |
| 4 | Gene expression signatures for phlegm-dampness constitution of Chinese Medicine显示文摘Dear Editor,The term'individualized medicine'was first used in Biochemistry Individuality in 1956 by Williams(Williams et al.,1956).With the emergence of the post-genome era in the21st century,individualized precision medicine has attracted increasing attention.In traditional Chinese medicine(TCM),there is also concept of individualized medicine,which is known as the Chinese constitutional theory,proposed in the1970s(Wang,2012).According to this theory,the | Lingru Li Juan Feng Haiqiang Yao Lan Xie Yu Chen Lingling Yang Shujuan Hou Shipeng Zhao Ranran Sun Yanling Wu Tongtong Bai Yingshuai Li Ruoxi Yu Ji Wang Qi Wang | 2017 | Science China(Life Sciences)2017，60，1： | 13 |
| 5 | Recent development of a refined multiple air pollutant emission inventory of vehicles in the Central Plains of China显示文摘Central Plains region of China,represented by Henan Province,is facing serious air pollution problems.Vehicular exhaust emissions had adverse impacts on the atmospheric environment.The first comprehensive and novel vehicle emission inventory for Henan Province using vehicle kilometers traveled,localized emission factors,and activity data at city-level was developed.Furthermore,3 km×3 km gridded emission and temporal variations were determined by using localized information.Results show that the total emissions of sulfur dioxide(SO2),nitrogen oxides(NOx),carbon monoxide(CO),particular matter with aerodynamic diameter<10μm(PM10),aerodynamic diameter<2.5μm(PM2.5),volatile organic compounds(VOCs),VOCs-evaporation and ammonia in 2015 were 9.1,533.4,1190.7,23.7,21.6,150.8,31.5 and 10.4 Gg,respectively,and the emission intensities of the above pollutants were 0.05,2.7,6.0,0.1,0.1,0.8,0.2 and 0.05 g/km,respectively.Vehicles meeting the Primary China 1,China 3 and China 4 contributed 89.1%,82.7%,75.3%,75.5%,75.5%,68.2%,68.4%and 82.3%for SO2,NOx,CO,PM10,PM2.5,VOCs,VOCs-evaporation and ammonia emissions,respectively.Zhengzhou,Zhoukou,Nanyang,Luoyang,Shangqiu and Xinyang showed relatively higher emissions and contributed more than 50%of each pollutant.The spatial distribution indicated obvious characteristics of the road network,and high-level emission was concentrated in the downtown areas.Additionally,the ozone formation potential(OFP)based on the estimated speciated VOC emissions was 569.6 Gg in Henan Province.Aliphatic and aromatic hydrocarbons were the main species of VOCs,whereas olefins contributed the largest proportion of OFP,with 42.2%. | Xingke Gu Shasha Yin Xuan Lu Huan Zhang Lingling Wang Ling Bai Chen Wang Ruiqin Zhang Minghao Yuan | 2019 | Journal of Environmental Sciences2019，31，10： | 11 |
| 6 | A natural variation in Ribonuclease H-like gene underlies Rht8 to confer“Green Revolution”trait in wheat显示文摘Dear Editor,Introduction of gibberellin(GA)-insensitive Reduced height(Rht)genes,Rht-B1b and Rht-D1b,has resulted in the“Green Revolution”in modern wheat cultivars(Triticum aestivum)that has skyrocketed wheat grain yields worldwide since the 1960s(Peng et al.,1999;Velde et al.,2021).However,Rht-B1b/D1b also reduce coleoptiles,which is undesired in dryland regions where deep planting is essential for seedling establishment(Rebetzke et al.,1999,Rebetzke et al.,2001;Ellis et al.,2004). | Lingling Chai Mingming Xin Chaoqun Dong Zhaoyan Chen Huijie Zhai Junhong Zhuang Xuejiao Cheng Naijiao Wang Jia Geng Xiaobo Wang Ruolin Bian Yingyin Yao Weilong Guo Zhaorong Hu Huiru Peng Guihua Bai Qixin Sun Zhenqi Su Jie Liu Zhongfu Ni | 2022 | Molecular Plant2022，15，3： | 8 |
| 7 | The role of transcriptional factor D-site-binding protein in circadian CCL2 gene expression in anti-Thy1 nephritis显示文摘Mesangial proliferative glomerulonephritis(MsPGN)is an inflammatory disease,but both the nature of disease progression and its regulation remain unclear.In the present study,we monitored the course of anti-Thy1 nephritis from days 1 to 5 and established gene expression profiles at each time point using microarrays to explore the development of inflammation.According to the gene expression profiles,macrophage infiltration(triggered by CCL2 activation)was evident on day 1 and enhanced inflammation over the next few days.We screened for genes with expression levels similar to CCL2 and found that the upregulation of the circadian gene albumin D-site-binding protein(DBP)was involved in CCL2 activation in mesangial cells.More importantly,CCL2 expression showed oscillatory changes similar to DBP,and DBP induced peak CCL2 expression at 16:00 a clock on day 1 in the anti-Thy1 nephritis model.We knocked down DBP through transfection with a small interfering RNA(siRNA)and used RNA sequencing to identify the DBP-regulated TNF-α-CCL2 pathway.We performed chromatin immunoprecipitation sequencing(ChIP-Seq)and the dual luciferase assay to show that DBP bound to the TRIM55 promoter,regulating gene expression and in turn controlling the TNF-α-CCL2 pathway.In conclusion,DBP-regulated circadian CCL2 expression by the TRIM55-TNF pathway in injured mesangial cells at an early stage,which promoted macrophage recruitment and in turn triggered infiltration and inflammation in a model of anti-Thy1 nephritis. | Yang Lu Yan Mei Lei Chen Lingling Wu Xu Wang Yingjie Zhang Bo Fu Xizhao Chen Yuansheng Xie Guangyan Cai Xueyuan Bai Qinggang Li Xiangmei Chen | 2019 | Cellular & Molecular Immunology2019，16，9： | 7 |
| 8 | The relationships of vitamin D, vitamin D receptor gene polymorphisms, and vitamin D supplementation with Parkinson's disease显示文摘In recent years,many studies have investigated the correlations between Parkinson's disease(PD)and vitamin D status,but the conclusion remains elusive.The present review focuses on the associations between PD and serum vitamin D levels by reviewing studies on the associations of PD with serum vitamin D levels and vitamin D receptor(VDR)gene polymorphisms from PubMed,Web of Science,Cochrane Library,and Embase databases.We found that PD patients have lower vitamin D levels than healthy controls and that the vitamin D concentrations are negatively correlated with PD risk and severity.Furthermore,higher vitamin D concentrations are linked to better cognitive function and mood in PD patients.Findings on the relationship between VDR gene polymorphisms and the risk of PD are inconsistent,but the Fokl(C/M)polymorphism is significantly linked with PD.The occurrence of Fokl(CT)gene polymorphism may influence the risk,severity,and cognitive ability of PD patients,while also possibly influencing the effect of Vitamin D3 supplementation in PD patients.In view of the neuroprotective effects of vitamin D and the close association between vitamin D and dopaminergic neurotransmission,interventional prospective studies on vitamin D supplementation in PD patients should be conducted in the future. | Lingling Lv Xuling Tan Xinke Peng Rongrong Bai Qile Xiao Ting Zou Jieqiong Tan Hainan Zhang Chunyu Wang | 2020 | Translational Neurodegeneration2020，9，3： | 5 |
| 9 | Statistical analysis of mesoscale eddy propagation velocity in the South China Sea deep basin显示文摘Using mesoscale eddy trajectory product derived from satellite altimetry data from 1993 to 2017,this study analyzes the statistical characteristics of spatiotemporal distribution of mesoscale eddy propagation velocities(C)in the South China Sea(SCS)deep basin with depths>1000 m.Climatologically,the zonal propagation velocities(cx)are westwards in the whole basin,and the meridional velocities(cy)are southwards in the northwestern basin,and northwards in the southeastern basin.The variation of cy with longitude is consistent with that of the background meridional currents with correlation coefficient R2 of 0.96,while the variation of cx is related both to the background zonal currents andβeffect.The propagation velocities characterize significant seasonality with the minimum magnitude occurring in summer and the maximum in winter for cx and C.Interannually,larger values of cx and cy mostly occurred in La Ni?a years in the negative phase of the Pacific Decadal Oscillation(PDO).Mesoscale eddies move fast at the beginning and end of their life span,i.e.,at their growth and dissipation periods,and slowly during their stable'midlife'period.This trend is negatively correlated with the rotating tangential velocity with R2 of–0.93.Eddies with extreme propagation velocities are defined,which are slower(faster)than 1.5 cm/s(15.4 cm/s)and take 1.5%(1.9%)of the total eddies.The extremely slow-moving(fastmoving)eddies tend to appear in the middle(on the edge)of the basin,and mostly occur in summer(winter).The mechanism analysis reveals that the spatiotemporal distributions of the propagation velocities of mesoscale eddies in the SCS are modulated by the basin-scale background circulation. | Runqi Huang Lingling Xie Quanan Zheng Mingming Li Peng Bai Keyi Tan | 2020 | Acta Oceanologica Sinica2020，39，11： | 4 |
| 10 | Preparation, microstructure and degradation performance of biomedical magnesium alloy fine wires显示文摘With the development of new biodegradable Mg alloy implant devices, the potential applications of biomedical Mg alloy fine wires are realized and explored gradually. In this study, we prepared three kinds of Mg alloy fine wires containing 4 wt% RE(Gd/Y/Nd) and 0.4 wt% Zn with the diameter less than 0.4 μm through casting, hot extruding and multi-pass cold drawing combined with intermediated annealing process. Their microstructures, mechanical and degradation properties were investigated. In comparison with the corresponding as-extruded alloy, the final fine wire has significantly refined grain with an average size of 3–4 μm, and meanwhile shows higher yield strength but lower ductility at room temperature. The degradation tests results and surface morphologies observations indicate that Mg–4Gd–0.4Zn and Mg–4Nd–0.4Zn fine wires have similar good corrosion resistance and the uniform corrosion behavior in SBF solution. By contrast, Mg–4Y–0.4Zn fine wire shows a poor corrosion resistance and the pitting corrosion behavior. | Jing Bai Lingling Yin Ye Lu Yiwei Gan Feng Xue Chenglin Chu Jingli Yan Kai Yan Xiaofeng Wan Zhejun Tang | 2014 | Progress in Natural Science:Materials International2014，24，5： | 3 |
| 11 | Carpel of cucumber (Cucumis sativus. L) male flowers maintains early primordia characteristics during organ development显示文摘Diclinism is not only an interesting natural phenomenon in plant kingdom, but also of significance in the yield of crops, e.g. cucumber and watermelon. Cucumber has been a model plant for studying the diclinism for decades. However, it is stili obscure how the carpel primordia of cucumber male flower undergo the developmental processes after the initiation of their development. By showing morphological alternation, metabolic activity, as well as CFL gene expression, the present study demonstrated that the carpel primordia of cucumber male flowers maintained the characteristics of primordium until anthesis, although it developed significantly slower than that of the female flowers. | YANG Lingling CHEN Min LIU Fuquan GENG Yi CHEN Chong LI Yiqin CAO Zongxun XU Zhihong BAI Shunong | 2000 | Chinese Science Bulletin2000，45，8： | 3 |
| 12 | Effects of wave-current interaction on the waves, cold-water mass and transport of diluted water in the Beibu Gulf显示文摘Wave-current interaction and its effects on the hydrodynamic environment in the Beibu Gulf(BG) have been investigated via employing the Coupled Ocean–Atmosphere–Wave–Sediment Transport(COAWST) modeling system. The model could simulate reasonable hydrodynamics in the BG when validated by various observations.Vigorous tidal currents refract the waves efficiently and make the seas off the west coast of Hainan Island be the hot spot where currents modulate the significant wave height dramatically. During summer, wave-enhanced bottom stress could weaken the near-shore component of the gulf-scale cyclonic-circulation in the BG remarkably, inducing two major corresponding adjustments: Model results reveal that the deep-layer cold water from the southern BG makes critical contribution to maintaining the cold-water mass in the northern BG Basin.However, the weakened background circulation leads to less cold water transported from the southern gulf to the northern gulf, which finally triggers a 0.2℃ warming in the cold-water mass area;In the top areas of the BG, the suppressed background circulation reduces the transport of the diluted water to the central gulf. Therefore, more freshwater could be trapped locally, which then triggers lower sea surface salinity(SSS) in the near-field and higher SSS in the far-field. | Jingling Yang Shaocai Jiang Junshan Wu Lingling Xie Shuwen Zhang Peng Bai | 2020 | Acta Oceanologica Sinica2020，39，1： | 2 |
| 13 | The Synthesis of Pyridine 2,6-dicarboxylic Acid Using Microwave Irradiation显示文摘 | Guofu Zhang Qing Zhang Hairui Zhang Lin Bai Helin Ye Lingling Liu | 2010 | Journal of Chemistry and Chemical Engineering2010，4，11： | 2 |
| 14 | Phthalate esters (PAEs) in indoor PM 10 /PM 2.5 and human exposure to PAEs via inhalation of indoor air in Tianjin, China显示文摘 | Leibo Zhang Fumei Wang Yaqin Ji Jiao Jiao Dekun Zou Lingling Liu Chunyan Shan Zhipeng Bai Zengrong Sun | 2013 | Atmospheric Environment2013，，： | 1 |
| 15 | SPH modeling of droplet impact on solid boundary显示文摘 | Li Darning Bai Ling Li Lingling | 2014 | Transactions of Tianjin University2014，20，： | 1 |
| 16 | Bio- logical characterization of chicken mesenchymal stem/pro- genitor cells from umbilical cord Wharton' s jelly 显示文摘 | BAI Chunyu LI Xiangcheng HOU Lingling | 2013 | Mol Cell Biochem2013，376，12： | 1 |
| 17 | Role of JNK Activation and Mitochondrial Bax Translocation in Allicin-Induced Apoptosis in Human Ovarian Cancer SKOV3 Cells显示文摘 | Ling Xu Jin Yu Dongxia Zhai Danying Zhang Wei Shen Lingling Bai Zailong Cai Chaoqin Yu Leo M. Lee | 2014 | Evidence-Based Complementary and Alternative Medicine2014，，： | 1 |
| 18 | Developing Analysis and Implementation of WebGIS显示文摘 | Wu Xincai Guo Lingling Bai Yuqi | 2004 | Computer Engineering and Applications2004，，5： | 1 |
| 19 | Milk-derived exosomes exhibit versatile effects for improved oral drug delivery显示文摘As endogenous courier vesicles,exosomes play crucial roles in macromolecule transmission and intercellular communication.Therefore,exosomes have drawn increasing attention as biomimetic drug-delivery vehicles over the past few years.However,few studies have investigated the encapsulation of peptide/protein drugs into exosomes for oral administration.Additionally,the mechanisms underlying their biomimetic properties as oral delivery vehicles remain unknown.Herein,insulin-loaded milk-derived exosomes(EXO@INS)were fabricated and the in vivo hypoglycemic effect was investigated on type I diabetic rats.Surprisingly,EXO@INS(50 and 30 IU/kg)elicited a more superior and more sustained hypoglycemic effect compared with that obtained with subcutaneously injected insulin.Further mechanism studies indicated that the origin of excellent oral-performance of milk-derived exosomes combined active multi-targeting uptake,pH adaptation during gastrointestinal transit,nutrient assimilation related ERK1/2 and p38 MAPK signal pathway activation and intestinal mucus penetration.This study provides the first demonstration that multifunctional milk-derived exosomes offer solutions to many of the challenges arising from oral drug delivery and thus provide new insights into developing naturally-equipped nanovehicles for oral drug administration. | Lei Wu Lingling Wang Xi Liu Yuli Bai Ruinan Wu Xiang Li Yutong Mao Ling Zhang Yongxiang Zheng Tao Gong Zhirong Zhang Yuan Huang | 2022 | Acta Pharmaceutica Sinica B2022，12，4： | 1 |
| 20 | Design,microwave-assisted synthesis and HIV-RT inhibitory activity of 2-(2,6-dihalophenyl)-3-(4,6-dimethyl-5-(un) substituted-pyrimidin-2-yl) thiazolidin-4-ones显示文摘 | CHEN Hua BAI Jie JIAO Lingling | 2009 | Bioorg Med Chem2009，17，： | 1 |
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