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| 1 | Chinese Stroke Association guidelines for clinical management of cerebrovascular disorders: executive summary and 2019 update of clinical management of ischaemic cerebrovascular diseases显示文摘Aim Stroke is the leading cause of disability and death in China.Ischaemic stroke accounts for about 60%-80%of all strokes.It is of considerable significance to carry out multidimensional management of ischaemic cerebrovascular diseases.This evidence-based guideline aims to provide the latest detailed and comprehensive recommendations on the diagnosis,treatment and secondary prevention of ischaemic cerebrovascular diseases.Methods We had performed comprehensive searches of MEDLINE(via PubMed)(before 30 June 2019),and integrated the relevant information into charts and distributed to the writing group.Writing group members discussed and determined the recommendations through teleconference.We used the level of evidence grading algorithm of Chinese Stroke Association to grade each recommendation.The draft was reviewed by the Guideline Writing Committee of Chinese Stroke Association Stroke and finalised.This guideline is fully updated every 3 years.results This evidence-based guideline is based on the treatment,care and prevention of ischaemic cerebrovascular diseases,which emphasises on pathogenesis evaluation,intravenous thrombolysis,endovascular therapy,antiplatelet therapy,prevention and treatment of complications,and risk factor management.Conclusions This updated guideline presents a framework for the management of ischaemic cerebrovascular diseases.Timely first-aid measures,professional care in the acute stage,and proactive secondary prevention will be helpful to patients. | Liping Liu Weiqi Chen Hongyu Zhou Wanying Duan Shujuan Li Xiaochuan Huo Weihai Xu Li'an Huang Huaguang Zheng Jingyi Liu Hui Liu Yufei Wei Jie Xu Yongjun Wang | 2020 | Stroke & Vascular Neurology2020,5,2: | 42 |
| 2 | Hippocampal gene expression in a rat model of depression after electroacupuncture at the Baihui and Yintang acupoints显示文摘Preliminary basic research and clinical findings have demonstrated that electroacupuncture therapy exhibits positive effects in ameliorating depression.However,most studies of the underlying mechanism are at the single gene level;there are few reports regarding the mechanism at the whole-genome level.Using a rat genomic gene-chip,we profiled hippocampal gene expression changes in rats after electroacupuncture therapy.Electroacupuncture therapy alleviated depression-related manifestations in the model rats.Using gene-chip analysis,we demonstrated that electroacupuncture at Baihui(DU20)and Yintang(EX-HN3)regulates the expression of 21genes.Real-time PCR showed that the genes Vgf,Igf2,Tmp32,Loc500373,Hif1a,Folr1,Nmb,and Rtn were upregulated or downregulated in depression and that their expression tended to normalize after electroacupuncture therapy.These results indicate that electroacupuncture at Baihui and Yintang modulates depression by regulating the expression of particular genes. | Dongmei Duan Xiuyan Yang2 Institute of Health Maintenance Beijing University of Chinese Medicine Ya Tu Liping Chen | 2014 | Neural Regeneration Research2014,9,1: | 16 |
| 3 | Endovascular treatment with or without intravenous alteplase for acute ischaemic stroke due to basilar artery occlusion显示文摘Background and purpose It remains controversial if endovascular treatment(EVT)can improve the outcome of patients with acute basilar artery occlusion(BAO).This study aims to compare the functional outcomes between EVT with and without intravenous thrombolysis(IVT)first in patients who had acute ischaemic stroke(AIS)due to BAO.Methods Patients who had AIS with BAO who underwent EVT within 24 hours of onset were enrolled in this multicentre cohort study,and the efficacy and safety were compared between IVT+EVT and direct EVT.The primary outcome was 90-day functional independence.All outcomes were assessed with adjusted OR(aOR)from the multivariable logistic regression.In addition,a meta-analysis was performed on all recently published pivotal studies on functional independence after EVT in patients with BAO.Results Of 310 enrolled patients with BAO,241(78%)were treated with direct EVT and 69(22%)with IVT+EVT.Direct EVT was associated with a worse functional outcome(aOR,0.46(95%CI 0.24 to 0.85),p=0.01).IVT+EVT was associated with a lower percentage of patients who needed≥3 passes of stent retriever(10.14%vs 20.75%).The meta-analysis regression revealed a potential positive correlation between bridging with IVT first and functional independence(r=0.14(95%CI 0.05 to 0.24),p<0.01).Conclusions This study showed that compared with direct EVT,EVT with IVT first was associated with better functional outcomes in patients with BAO treated within 24 hours of onset.The meta-analysis demonstrated similar favourable efficacy of IVT first followed by EVT in patients with BAO. | Ximing Nie David Wang Yuehua Pu Yufei Wei Qixuan Lu Hongyi Yan Xin Liu Lina Zheng Jingyi Liu Xinxuan Yang Yarong Ding Dacheng Liu Wanying Duan Zhe Zhang Zhonghua Yang Miao Wen Weibin Gu Xinyi Hou Xinyi Leng Yuesong Pan Zhongrong Miao Liping Liu | 2022 | Stroke & Vascular Neurology2022,7,3: | 10 |
| 4 | Characteristics analysis of a novel centralized-driving flip-flow screen显示文摘During screening operation, blinding or clogging of screen perforations generally occurs to reduce the sieving capacity and efficiency. Recently, the flip-flow screening has been widely recognized as a feasible method to deal with the problem. In this paper, a novel centralized-driving flip-flow screen(CFS) was developed for the separation of fine and moist coal, and the key structures, namely, a centralized-driving mechanism and a quasi-circle beam mounted with the mat were designed for high reliability and stability. By means of a test on an experimental prototype, the effect of some factors, i.e., initial stretch and hardness of the polyurethane panel, respectively, and the rotation speed of the driving motor on the kinematic characteristic of the screen surface was investigated. Results show that without an initial stretch, the sieve mat generates the largest vibratory amplitude while the slacker the sieve mat initially is, the smaller amplitude it will accomplish. And an increase in the rotation speed could cause a rise in the vibratory amplitude. Unlike the two factors, the hardness does not have a definite effect on the kinematic performance, on which a further study is required. Finally, screening processing on a laboratory prototype was conducted to draw the conclusion that the developed CFS also has a high sieving efficiency for the fine and moist coal. | Peng Liping Li Fengming Dong Hailin Liu Chusheng Zhao Yuemin Duan Chenlong | 2014 | International Journal of Mining Science and Technology2014,24,2: | 9 |
| 5 | Ablation of C/SiC-HfC composite prepared by precursor infiltration and pyrolysis in plasma wind tunnel显示文摘Carbon fiber reinforced silicon carbide-hafnium carbide(C/SiC-HfC)composite was prepared by precursor infiltration and pyrolysis process.Then,ablation behavior of C/SiC-HfC was evaluated in plasma wind tunnel.It was found that oxide layer formed during ablation significantly influenced the surface temperature.Formation of dense HfO2 SiO2 layer under low heat flux led to stable surface temperature.Silica(SiO2)on the surface was gradually consumed when heat flux increased,resulting in conversion of HfO2-SiO2 on the surface to HfO2.Converted HfO2 with high catalytic cofficient absorbed more energy,causing gradual increase in the surface temperature.Formed oxide layer was destroyed at high heat flux and high stagnation point pressure.After carbon fiber lost the protection of HfO2-SiO2 layer,it burned immediately,leading to surface temperature jump. | Liuyang DUAN Lei LUO Liping LIU Yiguang WANG | 2020 | Journal of Advanced Ceramics2020,9,3: | 7 |
| 6 | Feedrate scheduling method for constant peak cutting force in five-axis flank milling process显示文摘It is extremely important to select appropriate feedrates for the stable machining of parts with ruled surface in modern aviation industrial applications.However,the current studies take too much time to achieve this goal.Therefore,this paper presents an efficient feedrate optimization method for constant peak cutting force in five-axis flank milling process.The solution method of the instantaneous undeformed chip thickness(IUCT)is proposed using least squares theory with the cutter entry angle and feedrate as variables.Based on this method,an explicit analytical expression of the peak cutting force for each cutting point is established.Furthermore,a feedrate scheduling method is developed to quickly solve the appropriate feedrate under constant peak cutting force.To verify the proposed IUCT model,the fitting IUCT is compared with the accuracy data at different feedrates.Additionally,some experiments of five-axis flank milling are conducted to demonstrate the effectiveness of the peak force model and the feedrate scheduling method.And the surface roughness before and after feedrate scheduling is detected.The results show that the proposed feedrate scheduling method can quickly adjust the feedrate and ensure constant peak force during machining.At the same time,the surface quality is kept at a high level. | Liping WANG Xing YUAN Hao SI Feiyu DUAN | 2020 | Chinese Journal of Aeronautics2020,33,7: | 5 |
| 7 | Epstein-Barr virus-encoded RNAs as a survival predictor in nasopharyngeal carcinoma显示文摘 | Ke Kengjian Wang Haiyun Fu Sha Zhang Zichen Duan Liping Liu Dabo Ye Jin | 2014 | Chinese Medical Journal2014,,2: | 5 |
| 8 | LRP6 downregulation promotes cardiomyocyte proliferation and heart regeneration显示文摘The adult mammalian heart is thought to be a terminally differentiated organ given the postmitotic nature of cardiomyocytes.Consequently,the potential for cardiac repair through cardiomyocyte proliferation is extremely limited.Low-density lipoprotein receptor-related protein 6(LRP6)is a Wnt co-receptor that is required for embryonic heart development.In this study we investigated the role of LRP6 in heart repair through regulation of cardiomyocyte proliferation.Lrp6 deficiency increased cardiomyocyte cell cycle activity in neonatal,juvenile and adult mice.Cardiomyocyte-specific deletion of Lrp6 in the mouse heart induced a robust regenerative response after myocardial infarction(MI),led to reduced MI area and improvement in left ventricular systolic function.In vivo genetic lineage tracing revealed that the newly formed cardiomyocytes in Lrp6-deficient mouse hearts after MI were mainly derived from resident cardiomyocytes.Furthermore,we found that the pro-proliferative effect of Lrp6 deficiency was mediated by the ING5/P21 signaling pathway.Gene therapy using the adeno-associated virus(AAV)9 miRNAi-Lrp6 construct promoted the repair of heart injury in mice.Lrp6 deficiency also induced the proliferation of human induced pluripotent stem cell-derived cardiomyocytes(iPSC-CMs).Our study identifies LRP6 as a critical regulator of cardiomyocyte proliferation,which may lead to the development of a novel molecular strategy to promote myocardial regeneration and repair. | Yahan Wu Liping Zhou Hongyu Liu Ran Duan Huixing Zhou Fulei Zhang Xiaoyu He Dongbo Lu Ke Xiong Maolin Xiong Jinzhu Zhuang Yi Liu Li Li Dandan Liang Yi-Han Chen | 2021 | Cell Research2021,31,4: | 5 |
| 9 | Characteristics of pressure fluctuations and fine coal preparation in gas-vibro fluidized bed显示文摘To improve the separation efficiency of air dense medium fluidized beds for dry coal preparation,a gasvibro fluidized bed has been proposed in which magnetic powder is used as the heavy medium.Pressure fluctuations in the gas-vibro fluidized bed were investigated using time-and frequency-domain analysis methods.The relationship between pressure fluctuations,bubble behavior,and separation efficiency was established.The low amplitude of the standard deviation,the power spectral density(PSD),the incoherent-output PSD,and the high amplitude of the coherent-output PSD,which corresponds to the bubble behavior in the bed,were improved for coal preparation.The coal ash content was reduced from 42.55% to 16.54% by using the gas-vibro fluidized bed. | Liang Dong Yuemin Zhao Liping Peng Jie Zhao Zhenfu Luo Qingxia Liu Chenlong Duan | 2015 | Particuology2015,13,4: | 4 |
| 10 | Elliptical model for surface topography prediction in five-axis flank milling显示文摘In five-axis flank milling operations,the intersecting surfaces of different cutting edges create roughness on the milled surfaces that cannot be ignored in situations with strict requirements,especially in aeronautical manufacturing.To focus on motion problems in milling operations,this paper presents a new model that utilizes elliptical paths as cutting edge trajectories on 3D surface topography machined by peripheral milling.First,the cutter parallel axis offset and location angle are considered,which change the location of the ellipse center and intersection point of the cutting edges.Then,through the proposed model,the predicted surface topography is obtained,and the factors that affect the development tendency of roughness are analyzed.Next,the effects of the cutter location position(CLP)geometric parameters,cutter parallel axis offset and curvature on the roughness are evaluated by a numerical simulation.Finally,machining tests are carried out to validate the model predictions,and the results show that the surface topography predictions correspond well with the experimental results. | Liping WANG Shuyi GE Hao SIa Liwen GUAN Feiyu DUAN Yuzhe LIU | 2020 | Chinese Journal of Aeronautics2020,33,4: | 3 |
| 11 | Haemostatic therapy in spontaneous intracerebral haemorrhage patients with high-risk of haematoma expansion by CT marker: a systematic review and meta- analysis of randomised trials显示文摘Background and purpose Current randomised controlled trials(RCTs)showed an uncertain benefit of haemostatic therapy on preventing haematoma expansion and improving the outcome in patients with intracerebral haemorrhage(ICH).This meta-analysis aims to systematically evaluate the effect of haemostatic agents on the prevention of haemorrhage growth in patients with high-risk spontaneous ICH predicted by CT signs in RCTs.Methods A comprehensive search of PubMed,EMBASE and Cochrane library from 1 January 2005 to 30 June 2021 was conducted.RCTs that compared haemostatic agents with placebo for the treatment of spontaneous patients with ICH with high-risk haemorrhage growth were included.The primary endpoint was haematoma expansion at 24 hours.Other major endpoints of interest included 90-day functional outcome and mortality.Results The meta-analysis included four RCTs that randomised 2666 patients with ICH with high-risk haemorrhage growth.Haemostatic therapy reduced the rate of haematoma expansion at a marginally statistically significant level when compared with placebo(OR 0.84;95% CI 0.70 to 1.00;p=0.051).Subgroup analysis for patients with black hole sign on CT revealed a significant reduction of haematoma expansion with haemostatic therapy(OR 0.61;95% CI 0.39 to 0.94;p=0.03).However,both the primary analysis and subgroup analyses showed that haemostatic therapy could not reduce the rate of poor functional outcome(modified Rankin Scale>3)or death.Conclusions Haemostatic therapy showed a marginally significant benefit in reducing early haematoma expansion in patients with high-risk spontaneous ICH predicted by markers on CT scan.However,no significant improvement in functional outcome or reduction of mortality was observed. | Ximing Nie Jingyi Liu Dacheng Liu Qi Zhou Wanying Duan Yuehua Pu Zhonghua Yang Miao Wen Haixin Sun Wenzhi Wang Shengjun Sun Hongqiu Gu Liping Liu | 2021 | Stroke & Vascular Neurology2021,6,2: | 2 |
| 12 | Increased Expression of Colonic Mucosal Melatonin in Patients with Irritable Bowel Syndrome Correlated with Gut Dysbiosis显示文摘Dysregulation of the gut microbiota/gut hormone axis contributes to the pathogenesis of irritable bowel syndrome(IBS).Melatonin plays a beneficial role in gut motility and immunity.However,altered expression of local mucosal melatonin in IBS and its relationship with the gut microbiota remain unclear.Therefore,we aimed to detect the colonic melatonin levels and microbiota profiles in patients with diarrhea-predominant IBS(IBS-D)and explore their relationship in germ-free(GF)rats and BON-1 cells.Thirty-two IBS-D patients and twenty-eight healthy controls(HCs)were recruited.Fecal specimens from IBS-D patients and HCs were separately transplanted into GF rats by gavage.The levels of colon mucosal melatonin were assessed by immunohistochemical methods,and fecal microbiota communities were analyzed using 16S rDNA sequencing.The effect of butyrate on melatonin synthesis in BON-1 cells was evaluated by ELISA.Melatonin levels were significantly increased and negatively correlated with visceral hypersensitivity in IBS-D patients.GF rats inoculated with fecal microbiota from IBS-D patients had high colonic melatonin levels.Butyrate-producing Clostridium cluster XIVa species,such as Roseburia species and Lachnospira species,were positively related to colonic mucosal melatonin expression.Butyrate significantly increased melatonin secretion in BON-1 cells.Increased melatonin expression may be an adaptive protective mechanism in the development of IBS-D.Moreover,some Clostridium cluster XIVa species could increase melatonin expression via butyrate production.Modulation of the gut hormone/gut microbiota axis offers a promising target of interest for IBS in the future. | Ben Wang Shiwei Zhu Zuojing Liu Hui Wei Lu Zhang Meibo He Fei Pei Jindong Zhang Qinghua Sun Liping Duan | 2020 | Genomics, Proteomics & Bioinformatics2020,18,6: | 2 |
| 13 | Geniposide protects human neuroblastoma SH-SY5Y cells against corticosterone-induced injury显示文摘In vitro cultured human neuroblastoma SH-SY5Y cells were pretreated with 50 or 5 μg/mL geniposide for 12 hours and exposed to 400 μmol/L corticosterone. Corticosterone exposure in cultures not pretreated with geniposide resulted in inhibited cell growth, reduced cell survival, and increased P53 and P21 protein expression. However, in geniposide pretreated SH-SY5Y cells, cell viability and the number of cells in the G2 phase of the cell cycle were significantly increased, P21 and P53 protein expression was reduced, and cell apoptosis was inhibited following corticosterone exposure. These results indicate that geniposide can protect SH-SY5Y cells against high-dose corticosterone-induced injury. | Liping Chen Fawei Wang Miao Geng Hongyan Chen Dongmei Duan | 2011 | Neural Regeneration Research2011,6,21: | 2 |
| 14 | Core clock component MtLUX controls shoot architecture through repression of MtTB1/MtTCP1A in Medicago truncatula显示文摘Plants are capable of regulating their shoot architecture in response to diverse internal and external environments.The circadian clock is an adaptive mechanism that integrates information from internal and ambient conditions to help plants cope with recurring environmental fluctuations.Despite the current understanding of plant circadian clock and genetic framework underlying plant shoot architecture,the intricate connection between these two adaptive mechanisms remains largely unclear.In this study,we elucidated how the core clock gene LUX ARRHYTHMO(LUX)regulates shoot architecture in the model legume plant Medicago truncatula.We show that mtlux mutant displays increased main stem height,reduced lateral shoot length,and decreased the number of lateral branches and biomass yield.Gene expression analysis revealed that Mt LUX regulated shoot architecture by repressing the expression of strigolactone receptor MtD14 and MtTB1/MtTCP1A,a TCP gene that functions centrally in modulating shoot architecture.In vivo and in vitro experiments showed that Mt LUX directly binds to a cis-element in the promoter of MtTB1/MtTCP1A,suggesting that Mt LUX regulates branching by rhythmically suppressing MtTB1/MtTCP1A.This work demonstrates the regulatory effect of the circadian clock on shoot architecture,offering a new understanding underlying the genetic basis towards the flexibility of plant shoot architecture. | Liping Wang Anqi Zhou Lulu Wang Jing Li Mingkang Yang Tingting Duan Jian Jin Liang Chen Liangfa Ge Wei Huang | 2023 | The Crop Journal2023,11,3: | 2 |
| 15 | Fluorouracil-based preoperative chemoradiotherapy with or without oxaliplatin for stage Ⅱ/Ⅲ rectal cancer:a 3-year follow-up study显示文摘Background:Fluorouracil-based preoperative chemoradiotherapy has become the standard treatment for stage II/III rectal cancer.In order to improve the overall survival(OS) and disease-free survival(DFS),we added oxaliplatin to the standard treatment,and compared the effectiveness of these two treatment patterns.Methods:A total of 206 patients enrolled in the prospective study had histologically confirmed rectal cancer of clinical stage II/III during July 2007 to July 2010.They were randomized into the experimental group received oxaliplatin and capecitabine in combination with radiotherapy,and the control group received capecitabine in combination with radiotherapy.All patients received surgery in 6-10 weeks after chemoradiotherapy and adjuvant chemotherapy with m FOLFOX6.The primary endpoints were DFS and OS,and the secondary endpoints included toxicity,compliance,and histopathological response.Results:The 3-year OS in the experimental group and the control group was 90.29% vs.86.41%(P>0.05),and the 3-year DFS was 80.58% vs.69.90%(P>0.05).The pathological complete remission(p CR) rates were 23.30% and 19.42%,respectively(P=0.497).The 3-year local recurrence rates were 4.85% vs.5.83%(P=0.694),and the 3-year distant metastasis rates were 16.50% and 28.16%,respectively(P=0.045).There were no significant differences in most grade 3-4 toxicities between two groups,however,grade 3-4 diarrhea occurred in 16.50%(17/103) of the experimental group,compared with 6.80%(7/103) of the control group(P=0.030).Also,the total grade 3-4 acute toxicity showed a significant difference(10.68% vs.21.36%,P=0.037).Conclusions:The experimental treatment did not lead significantly improved OS and DFS,and thus longer follow-up is warranted for our patient cohort.Adding oxaliplatin to capecitabine-based preoperative chemoradiotherapy can significantly reduce metastasis,but has only minimal impact on local recurrence.Although grade 3-4 toxicity rate increased(primarily gastrointestinal toxicity),patients can stand to be followed up with allopathic treatment. | Dexin Jiao Rui Zhang Zhiqiang Gong Fang Liu Yue Chen Qinrui Yu Liping Sun Hongyan Duan Shendong Zhu Fei Liu Jian Wang Jianhui Jia | 2015 | Chinese Journal of Cancer Research2015,27,6: | 2 |
| 16 | Mechanism of variations in environmental magnetic proxies of lake sediments from Nam Co, Tibet during the Holocene显示文摘High-resolution environmental records from the Tibetan Plateau are essential to understand past global climatic and environmental changes. Magnetic minerals in lake sediments are important proxies to reconstruct environmental and climatic changes. Nam Co (lake) is a typical great lake in the transitional region of southwest monsoon in the Tibetan Plateau. Previous studies have extensively focused on geochemistry, microfossils, sedimentology and biochemistry analysis of Nam Co, which provides sound interpretation of paleoclimatic and paleoenvironmental changes. However, up to now, no systematic environmental magnetic studies have been carried out. Therefore, high-resolution and systematic magnetic studies combined with geochemical parameters were carried on lake sediments of core NC 08/01 from Nam Co for the Holocene period (11.3 cal ka BP) in order to explore how magnetic properties of the sediments respond to climatic changes. Based on variations of magnetic proxies, the sequence can be separated into 3 units. Unit 1 (236-199 cm, 11.3-7.8 cal ka BP) contains dominantly coarse-grained magnetite with homogeneous grain size. A positive correlation between magnetite and Ti strongly suggests that these coarse-grained detrital magnetites reflect detrital input signals due to insignificant effects of postdepositional dissolution processes on these coarse-grained magnetite particles. For Unit 2 (198-102 cm, 7.8-2.1 cal ka BP), magnetic grain size is finer and the corresponding concentration of magnetite is also reduced. This is mainly due to significant dissolution of these fine-grained detrital magnetite particles, which were transported under reduced water flow conditions during this period. For Unit 3 (101-0 cm, 2.1-0 cal ka BP), the bulk magnetic properties are dominated by a mixture of single domain biogenic magnetite and detrital magnetite. The concentration of magnetic minerals is not correlated with the Ti content. In conclusion, the preservation of magnetic minerals in the lake sediment and thus the corresponding magnetic properties are related to the initial grain size. Combination of magnetic properties (including variation of grain size and concentration) and other proxies of detrital inputs (e.g. Ti) can be used to infer the variation of redox conditions in Nam Co. These results provide a viable framework for reconstructing the paleoenvironmental changes of this lake. | SU YouLiang GAO Xing LIU QingSong HU PengXiang DUAN ZongQi JIANG ZhaoXia WANG JunBo ZHU LiPing DOBERSCHüTZ Stefan MUSBACHER Roland DAUT Gerhard HABERZETTL Torsten | 2013 | Chinese Science Bulletin2013,58,13: | 2 |
| 17 | Impaired Parahippocampal Gyrus-Orbitofrontal Cortex Circuit Associated with Visuospatial Memory Deficit as a Potential Biomarker and Interventional Approach for Alzheimer Disease显示文摘The parahippocampal gyrus-orbitofrontal cortex(PHG-OFC)circuit in humans is homologous to the postrhinal cortex(POR)-ventral lateral orbitofrontal cortex(vlOFC)circuit in rodents.Both are associated with visuospatial malfunctions in Alzheimer’s disease(AD).However,the underlying mechanisms remain to be elucidated.In this study,we explored the relationship between an impaired POR-vlOFC circuit and visuospatial memory deficits through retrograde tracing and in vivo local field potential recordings in 5XFAD mice,and investigated alterations of the PHG-OFC circuit by multi-domain magnetic resonance imaging(MRI)in patients on the AD spectrum.We demonstrated that an impaired glutamatergic POR-vlOFC circuit resulted in deficient visuospatial memory in 5XFAD mice.Moreover,MRI measurements of the PHG-OFC circuit had an accuracy of 77.33%for the classification of amnestic mild cognitive impairment converters versus non-converters.Thus,the PHG-OFC circuit explains the neuroanatomical basis of visuospatial memory deficits in AD,thereby providing a potential predictor for AD progression and a promising interventional approach for AD. | Lin Zhu Zan Wang Zhanhong Du Xinyang Qi Hao Shu Duan Liu Fan Su Qing Ye Xuemei Liu Zheng Zhou Yongqiang Tang Ru Song Xiaobin Wang Li Lin Shijiang Li Ying Han Liping Wang Zhijun Zhang | 2020 | Neuroscience Bulletin2020,36,8: | 2 |
| 18 | Eosinophilic gastroenteritis:Clinical manifestations and morphological characteristics,a retrospective study of 42 patients显示文摘 | Li Zhang Liping Duan Shigang Ding | | 0,,: | 1 |
| 19 | Analytical solutions to rate equations including losses describing threshold pumped fiber lasers显示文摘 | Zhichun Duan Liping Zhang Jianguo Chen | | Optik0,,: | 1 |
| 20 | Analytical characterization of an end pumped rare - earth - doped double - clad fiber laser显示文摘 | Zhichun Duan Liping Zhang Jianguo Chen | 2007 | Optical Fiber Technology2007,13,: | 1 |