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| 1 | Palaeoproterozoic Khondalite Belt in the western North China Craton: New evidence from SHRIMP dating and Hf isotope composition of zircons from metamorphic rocks in the Bayan Ul-Helan Mountains area显示文摘Zircom U-Pb age and Hf isotope analyses were made on gneissic granite and garnet-mica two-feldspar gneiss from the Helanshan Group in the Bayan Ul-Helan Mountains area, the western block of the North China Craton (NCC). Zircons from the gneissic granite commonly show core-mantle-rim structures, with magmatic core, metamorphic mantle and rim having ages of 2323±20 Ma, 1923±28 Ma and 1856±12 Ma, respectively. The core, mantle and rim show similar Hf isotope compositions, with single-stage depleted mantle model ages (TDM1) of 2455 to 2655 Ma (19 analyses). Most of the detrital zircons from the garnet-mica two-feldspar paragneiss have a concentrated U-Pb age distribution, with a weighted mean 207Pb/206Pb age of 1978±17 Ma. A few detrital zircons are older (2871 to 2469 Ma). The age for metamorphic overgrown rim was not determined because of strong Pb loss due to their high U content. The zircons show large variation in Hf isotope composition, with TDM1 ages of 1999 to 3047 Ma. In com- bination with previous studies, the main conclusions are as follows: (1) protolith of the khondalite se- ries in the Helanshan Group formed during Palaeoproterozoic rather than the Archaean as previously considered; (2) The results lend support to the contention that there is a huge Palaeoproterozoic Khondalite (metasedimentary) Belt between the Yinshan Mountains Block and the Ordos Block in the Western Block of NCC; (3) The widely-distributed bodies of early Palaeoproterozoic orthogneisses in the Khondalite Belt might be one of the important sources for detritus material in the khondalite series; (4) Collision between the Yinshan Block, the Ordos Block and the Eastern Block occurred in the same tectonothermal event of late Palaeoproterozoic, resulting in the final assembly of the NCC. | DONG ChunYan LIU DunYi LI JunJian WAN YuSheng ZHOU HongYing LI ChengDong YANG YueHeng XIE LieWen | 2007 | Chinese Science Bulletin2007，52，21： | 52 |
| 2 | Formation ages and source regions of the Palaeoproterozoic Gaofan, Hutuo and Dongjiao groups in the Wutai and Dongjiao areas of the North China Craton from SHRIMP U-Pb dating of detrital zircons: Resolution of debates over their stratigraphic relationships显示文摘这份报纸在北方中国 Craton 的 Wutai 和 Dongjiao 区域报导 Gaofan, Hutuo 和 Dongjiao 组的元沉积的岩石的由岩屑形成的锆石年龄分布。由岩屑形成的锆石一从 Gaofan 组的 quartzite 主要是在年龄的 2.5 Ga,与大约 2.7 Ga 并且更旧。A 石英岩从 Hutuo 组的基础集团企业的卵石在到 Gaofan 组的 quartzite 的由岩屑形成的锆石年龄分发是类似的。为从 Dongjiao 组的 meta-feldspar-quartz 沙岩,由岩屑形成的锆石的年龄主要在 2.5 Ga 被集中。比 2.6 Ga 旧的锆石都没被识别,但是在年龄与一些是 1.84 Ga 和 2.22.0 Ga。与更早的研究结合了,下列结论能被得出:(1 ) Gaofan 组是在年龄的早 Palaeoproterozoic 并且对迟了的 Neoarchaean Wutai 花岗石绿岩岩层年轻得多、无关,它 unconformably 躺它。因此, Gaofan 组是在诺思中国 Craton 的最旧的 Palaeoproterozoic 元沉积的单位之一。(2 ) Hutuo 组在一个大陆人地下室上在中间的 Palaeoproterozoic (2.14-2.09 Ga ) 被扔,在早 Palaeoproterozoic Gaofan 组后面。(3 ) Dongjiao 组在 1.84 Ga 以后被形成,并且可能属于 Changcheng 系统的更低的部分。(4 ) 从所有三个组的由岩屑形成的锆石显示出 2.5 Ga 的一座明显的年龄山峰,从在北方中国 Craton 在太古代的结束在强烈 tectono-magma-thermal 事件形成的火的岩石被采购。 | WAN YuSheng MIAO PeiSheng LIU DunYi YANG ChongHui WANG Wei WANG HuiChu WANG ZheJiu DONG ChunYan DU LiLin ZHOU HongYing | 2010 | Chinese Science Bulletin2010，55，13： | 32 |
| 3 | PROTAC-induced BTK degradation as a novel therapy for mutated BTK C481S induced ibrutinib-resistant B-cell malignancies显示文摘 | Yonghui Sun Xingwang Zhao Ning Ding Hongying Gao Yue Wu Yiqing Yang Meng Zhao Jinseok Hwang Yuqin Song Wanli Liu Yu Rao | 2018 | Cell Research2018，28，7： | 29 |
| 4 | Formation age and tectonic environment of the Gantaohe Group,North China Craton:Geology,geochemistry,SHRIMP zircon geochronology and Hf-Nd isotopic systematics显示文摘The Gantaohe Group is an important early Precambrian unit in the Trans-North China Orogen,North China Craton,and is mainly composed of greenschist-facies metabasalt,meta-sandstone and dolomitic marble.We report whole-rock geochemical compositions and SHRIMP zircon ages as well as LA-ICP-MS Hf-in-zircon isotopeic analyses for metabasalts from the Gantaohe Group.SHRIMP dating yielded a weighted mean 207Pb/206Pb age of 2087±16 Ma(MSWD=1.3) for magmatic zircons,but there are also abundant ca.2.5 Ga inherited zircon xenocrysts.The magmatic zircons shows a large Hf(t) variation in Hf(t) from 7.17 to +0.45,suggesting an isotopically highly heterogeneous source for the metabasalt.Chemically all samples show no distinct Zr or Hf anomalies,and some samples show no Nd or Ta anomalies in a primitive mantle-normalized trace element variation diagram,and their whole-rock Nd(t) values range from 4.0 to 0.8.We suggest that the basalt is formed by partial melting of a depleted mantle source,followed by significant crustal contamination.Field observations,the presence of abundant inherited zircon,as well as isotope and trace elements geochemistry support formation of the Gantaohe Group on top of a continental basement.These data and the regional geology lead us to conclude that the Trans-North China Orogen constituted an intracontinental rift during the Paleoproterozoic that was connected to the Eastern Block since the end of the Archean. | XIE HangQiang LIU DunYi YIN XiaoYan ZHOU HongYing YANG ChongHui DU LiLin WAN YuSheng | 2012 | Chinese Science Bulletin2012，57，36： | 16 |
| 5 | Analysis of the changes of volatile flavor compounds in a traditional Chinese shrimp paste during fermentation based on electronic nose,SPME-GC-MS and HS-GC-IMS显示文摘Traditionally fermented shrimp paste has a long fermentation period and is susceptible of external factors,which leads to unstable quality and limits its development and application.Therefore,the purpose of this study is to analyze the flavor changes in the shrimp paste fermentation process and screen out the key volatile aroma components in the shrimp paste to control the flavor quality of the shrimp paste products.The overall odor profile was detected by the electronic nose.A total of 106 volatile flavor compounds in the shrimp paste samples at different fermentation stages were identified by solid-phase microextraction-gas chromatography-mass spectrometry(SPME-GC-MS)and headspace-gas chromatography-ion mobility spectrometry(HS-GC-IMS).The main aroma components alcohols,aldehydes,pyrazines and other substances in the fermentation process showed an overall upward trend.A total of 17 key volatile aroma components in shrimp paste at different fermentation stages were identified by the relative aroma activity value(ROAV)method.The combination of electronic nose,SPME-GC-MS and HS-GC-IMS could comprehensively reflect the changes of volatile components in shrimp paste at different fermentation stages,which helps to further understand the mechanism of shrimp paste flavor formation and provides a basis for the regulation of the flavor quality of shrimp paste products. | Ying Li Li Yuan Huijie Liu Hongying Liu Yue Zhou Miaonan Li Ruichang Gao | 2023 | Food Science and Human Wellness2023，12，1： | 16 |
| 6 | Natural Variations at TIG1 Encoding a TCP Tran scription Factor Contribute to Plant Architecture Domestication in Rice显示文摘The modification of plant architecture is a crucial target in rice domestication and modern genetic improvement.Although several genes regulating rice plant architecture have been characterized,the molecular mechanisms underlying rice plant architecture domestication remain largely unclear.Here we show that the inclined tiller growth in wild rice is controlled by a single dominant gene,TILLER INCLINED GROWTH 1 (T/Gf),which is located on chromosome 8 and encodes a TCP transcriptional activator.TIG1 is primarily expressed in the adaxial side of the tiller base,promotes cell elongation,and enlarges the tiller angle in wild rice.Variations in the TIG1 promoter of indica cultivars {tig1 allele) resulted in decreased expression of TIG1 in the adaxial side of tiller base and reduced cell length and tiller angle,leading to the transition from inclined tiller growth in wild rice to erect tiller growth during rice domestication.TIG1 positively regulates the expression of EXP A3,EXPB5,and SAUR39 to promote cell elongation and increase the tiller angle.Selective sweep analysis revealed that the tig1 allele was selected in indica cultivars by human beings.The cloning and characterization of TIG1 supports a new scenario of plant architecture evolution in rice. | Weifeng Zhang Lubin Tan Hongying Sun Xinhui Zhao Fengxia Liu Hongwei Cai Yongcai Fu Xianyou Sun Ping Gu Zuofeng Zhu Chuanqing Sun | 2019 | Molecular Plant2019，12，8： | 13 |
| 7 | Progress and Applications of Visual SLAM显示文摘Visual simultaneous localization and mapping (SLAM) provides mapping and self-localization results for a robot in an unknown environment based on visual sensors, that have the advantages of small volume, low power consumption, and richness of information acquisition. Visual SLAM is essential and plays a significant role in supporting automated and intelligent applications of robots. This paper presents the key techniques of visual SLAM, summarizes the current research status, and analyses the new trends of visual SLAM research and development. Finally, specific applications of visual SLAM in restricted environments, including deep space and indoor scenarios, are discussed. | Kaichang DI Wenhui WAN Hongying ZHAO Zhaoqin LIU Runzhi WANG Feizhou ZHANG | 2019 | Journal of Geodesy and Geoinformation Science2019，2，2： | 11 |
| 8 | Geochronology, Geochemistry and Tectonic Significance of the Early Carboniferous Gabbro and Diorite Plutons in West Ujimqin, Inner Mongolia显示文摘Early Carboniferous gabbros and diorites are distributed in West Ujimqin, Inner Mongolia. The LA-ICP-MS zircon U-Pb ages of the gabbro and diorite samples are 321± 2 Ma(MSWD=0.65) and 319.4± 1.5 Ma(MSWD=0.42), respectively. In addition, new geochemistry data from three gabbro and three diorite samples are presented. All six samples show high Al_2O_3 contents but low-TiO_2 contents, belonging to tholeiitic and calc-alkali basalt series. All of the samples have similar chondrite normalized REE patterns characterized by moderate depletion in LREE similar to normal middle oceanic ridge basalt(MORB). The MORB and PM-normalized trace element patterns show the enrichment in large ion lithophile elements(LILE, e.g., Rb, Ba and Sr), depletion in high field strength elements(HFSE) and distinctly negative Nb and Ta anomalies similar to volcanic arc basalt. Furthermore, as shown in the correlation plots of La/Ba vs. La/Nb, Ba/La vs. Ce/Pb, Th/La vs. Ce/Pb, Nb/La vs. Ba/Rb, and Nb/Y vs. La/Yb, the magma source has underwent contamination and metasomatism from the subduction fluid. According to the Zr/Nb, La/Nb, and La/Ta ratios and the Nb/Y vs. Zr/Y and Sm/Yb vs. La/Sm diagrams, the magma was derived from shallow depleted lithospheric mantle and formed by moderate(5%~20%) partial melting of spinel lherzolites. Tectonic setting discrimination diagrams reveal that the gabbros and diorites display both characteristics of MORB and volcanic arc basalt, which is consistent with their geochemical characteristics. On the basis of the geochemical features of these samples, combined with regional geological data and many previous researches in the study area, the Early Carboniferous gabbros and diorites of West Ujimqin are suggested to be formed in an intensely extensional rift setting, and a limited immature ocean basin probably formed after subsequent development. | Shiwei Ma Changfeng Liu Zhiqin Xu Zhiguang Zhou Jinyuan Dong Hongying Li | 2017 | Journal of Earth Science2017，28，2： | 10 |
| 9 | Metal-free porous nitrogen-doped carbon nanotubes for enhanced oxygen reduction and evolution reactions显示文摘开发有效没有金属的双性人功能的 electrocatalysts 被要求减少费用并且改进慢氧减小反应(ORR ) 和氧进化反应(OER ) 在电气化学的系统的动力学。多孔的做 N 的碳 nanotubes (NCNT ) 被 KOH 激活和 polypyrrole nanotubes 的热分解制作。NCNT 拥有了超过 1,000 的一个大表面区域 ? m 2?g1 。NCNT electrocatalysts,特别地,那些在 900 点退火了 ? 椠 ? 捡楴楶祴猠慴敧 ? 湡 ? 祤慮業? 敭档湡獩 ??? 桴獩猠畴祤 ? 敷爠灥牯 ? 桴 ? 牁档慥? ㈨?? | Ting Pan Hongying Liu Guangyuan Ren Yunan Li Xianyong Lu Ying Zhu | 2016 | Science Bulletin2016，61，11： | 10 |
| 10 | Distribution and Provenance of Detrital Minerals in Southern Coast of Shandong Peninsula显示文摘Detrital minerals of 137 offshore and 22 river sediment samples collected from Qingdao coastal areas have been analyzed. Four mineral assemblage provinces can be classified by Q-mode cluster analysis. Factor analysis identifies two major factors that account for the total variability in most common minerals: 1) based on the relationship of quartz, hornblende, actinolite, micas, and authigenic pyrite, 41.55% of the variability is related to sediment sources; 2) based on the relationship of epidote, garnet, sphere, and ilmenite, 23.21% can be related to strong hydrodynamic conditions that control transport and sedimentation. By comparing mineral compositions of river waters in the study area, the following four mineral provenances can be identified. The Qingdao-Laoshan nearshore area has a quartz-feldspar-epidote-hornblende-limenite-limonite-sphene assemblage, which is largely attributed to relict sediment and coastal erosion. The Jimo-Haiyang nearshore area has a quartz-feldspar-hornblende-epidote-limonite-mica-actinolite assemblage, derived largely from the Wulong River and Rushan River, and is also affected by the Huanghe River, while the Qianliyan Island area in the deeper offshore area separated by a mud belt has a similar assemblage. The Haiyang-Rushan nearshore area has a quartz-feldspar-hornblende-epidote-micas-limonite assemblage, indicating multiple sources from the Rushan River, the Wulong River, the Huanghe River, and coastal erosion. The central area, located in an eddy center, has a mica-authigenic pyrite-hornblende-quartz-feldspar assemblage, indicating multiple sources dominated by Huanghe River distal sediments. | LIU Jinqing YIN Ping ZHANG Yong SONG Hongying BI Shipu CAO Zhimin LIU Shanshan | 2017 | Journal of Ocean University of China2017，16，5： | 9 |
| 11 | Removal of polycyclic aromatic hydrocarbons from different soil fractions by persulfate oxidation显示文摘Removal of polycyclic aromatic hydrocarbons(PAHs) from different soil fractions of contaminated soil was investigated by using activated persulfate oxidation remediation in our research. The results showed that the light fraction, which accounted for only 10% of the soil, contained 30% of the PAHs at a concentration of 4352 mg/kg. The heavy fraction contained more high-molecular-weight PAHs, and the total PAH concentration was 625 mg/kg. After being oxidized, the removal rate of PAHs was 39% in the light fraction and nearly 90% in the heavy fraction. Among the different fractions of the heavy fraction,humic acid contained the highest concentration of PAHs, and consequently, the highest removal efficiency of PAHs was also in humic acid. Compared with the light fraction, the heavy fraction has more aromatic compounds and those compounds were broken down during the oxidation process, which may be the removal mechanism involved in the oxidation of high-ring PAHs. Similarly, the enhancement of C= C bonds after oxidation can also explain the poor removal of high-ring PAHs in the light fraction. These results imply that different fractions of soil vary in composition and structure, leading to differences in the distribution and oxidation efficiencies of PAHs. | Xiaoyong Liao Qiongzhi Liu You Li Xuegang Gong Hongying Cao | 2019 | Journal of Environmental Sciences2019，31，4： | 8 |
| 12 | Growth and Repair Potential of Three Species of Bacteria in Reclaimed Wastewater after UV Disinfection显示文摘Objective The growth and repair potential of three typical microorganisms in reclaimed water after UV disinfection was investigated to assess the effects of photo-reactivation and dark repair of microorganisms,and the microbial safety of reclaimed water following this procedure.Methods The growth and repair potential of Escherichia coli,a fecal coliform strain and Bacillus subtilis in the effluent of a biological wastewater treatment plant disinfected by a low-pressure UV lamp were investigated.Results Any increase in bacterial numbers in the effluent after UV disinfection was due to damage repair.Exposure to photo-reactivating light for 8-10 h after UV irradiation with a dose of 5 mJ/cm 2,the highest percentage of photo-reactivation observed for E.coli and the fecal coliform strain was 29% and 15% respectively.B.subtilis showed little photo-reactivation under these conditions.The percentage of photo-reactivation was related to the UV dose and the photo-reactivating time,and a function was developed to forecast the final concentrations of E.coli and the fecal coliform strain after UV disinfection with possible photo-reactivation.Conclusion Different species of bacteria displayed different responses to UV light and different repair potentials.The repair of indigenous bacteria in wastewater needs to be investigated in future work. | GUO MeiTing HUANG JingJing HU HongYing LIU WenJun | 2011 | Biomedical and Environmental Sciences2011，24，4： | 8 |
| 13 | Effect of Different Aging Processes on the Microstructure and Mechanical Properties of a Novel Al–Cu–Li Alloy显示文摘The effects of different aging processes on the microstructure and mechanical properties of a novel Al–Cu–Li alloy have been investigated by X-ray diffraction, scanning electron microscopy and transmission electron microscopy. It is found that the tensile properties of a novel Al–Cu–Li alloy are sensitive to aging processes, which correspond to different microstructures. σ(Al_5Cu_6Mg_2) and T_1(Al_2CuLi) phases are the major precipitates for the alloy in T6 aging condition(165 ℃/60 h). After duplex aging condition(150 ℃/24 h + 180 ℃/12 h), σ, θ'(Al_2Cu) and T_1 phases are detected. Only the T_1 phases can be found in the T8 state alloy(6% pre-strain+135 ℃/60 h). The failure modes of alloy in T6 and duplex aging conditions are dimple-intergranular fracture, while typical quasi-cleavage fracture in T8 condition. | Hongying Li Desheng Huang Wei Kang Jiaojiao Liu Yangxun Ou Dewang Li | 2016 | Journal of Materials Science & Technology2016，32，10： | 8 |
| 14 | Synthesis and applications of mesoporous Cu-Zn-Al_2O_3 catalyst for dehydrogenation of 2-butanol显示文摘A series of mesoporous Cu-Zn-Al2O3 materials have been synthesized at ambient temperature and their structure was characterized by XRD, N2 physical adsorption and TPR techniques. Their catalytic applications for the dehydrogenation of 2-butanol to methyl ethyl ketone (MEK) were evaluated in a fixed-bed flow reactor at atmospheric pressure. It is demonstrated from the XRD patterns that both the as-synthesized samples and calcined samples have the typical XRD patterns of meso-structured materials and the results of N2O chemical adsorption showed that Cu was embedded in the framework of the mesoporous materials and homogeneously dispersed in the mesoporous Cu-Zn-Al2O3 materials. The catalytic activity of 2-butanol dehydrogenation was varied in the order of CZA(10) | Deren Fang Wanzhong Ren Zhongmin Liu Xiufeng Xu Lei Xu Hongying Lǔ Weiping Liao Huimin Zhang | 2009 | Journal of Natural Gas Chemistry2009，18，2： | 7 |
| 15 | Effectiveness of acupuncture versus spinal-epidural anesthesia on labor pain: a randomized controlled trial显示文摘OBJECTIVE: To evaluate the effectiveness of acupuncture analgesia(AA) compared with combined spinal-epidural anesthesia(CSEA) for labor pain relief and labor outcomes.METHODS: We evaluated 131 primiparous women who received respiratory guidance during maternal uterine contractions and received either AA(n =43), CSEA(n = 45), or no additional treatment(control, n = 43). The groups were compared regarding visual analog scale(VAS) scores for abdominal and back pain, and labor outcomes.RESULTS: The abdominal VAS scores of the AA and CSEA groups were significantly lower than that of the control group. In addition, the VAS scores of the CSEA group were significantly lower than that of the AA group at 10 and 60 min after intervention.The back pain VAS scores of the AA and CSEA groups were significantly lower than that of the control group at 5, 10, and 60 min after intervention. The duration of the active phase of labor in the CSEA group was significantly longer than that of the AA and control groups. The rates of oxytocin use(4.70%), urinary retention(4.70%), and postpartum hemorrhage [(273.7 ± 53.6) m L] in the AA group were significantly lower than in the CSEA group [46.70%, 24.20%, and(320.0 ± 85.6) m L, respectively].CONCLUSION: Both AA and CSEA were effective for labor pain relief, CSEA provided more effective pain relief, while AA was associated with a shorter duration of labor and fewer adverse effects.and each has its advantages and disadvantages. | Wu Lingling Liu Xiaohui Yin Yuzhu Sun Ke Wu Ling Yi Wei Li Shangrong Hou Hongying | 2017 | Journal of Traditional Chinese Medicine2017，37，5： | 7 |
| 16 | Comparison of the short-term and long-term outcomes of laparoscopic hysterectomies and of abdominal hysterectomies: a case study of 4,895 patients in the Guangxi Zhuang Autonomous Region, China显示文摘Background: To evaluate the short-term and long-term outcomes after laparoscopic hysterectomy(LH) compared with abdominal hysterectomy(AH) in case of benign gynecological disease. Methods: A multi-center cohort retrospective comparative study of population among 4,895 hysterectomies(3,539 LH vs.1,356 AH) between 2007 and 2013 was involved. Operative time(OT), estimated blood loss(EBL), intra-operative and post-operative complications, passing flatus; days with indwelling catheter, questionnaires covering pelvic floor functions and sexual functions were assessed.Results: The EBL(174.1±157.4 vs. 263.1±183.2 cc, LH and AH groups, respectively), passing flatus(38.7±14.1 vs. 48.1±13.2 hours), days with indwelling catheter(1.5±0.6 vs. 2.2±0.8 days), use of analgesics(6.5% vs. 73.1%), intra-operative complication rate(2.4% vs. 4.1%), post-operative complication rate(2.3% vs. 5.7%), post-operative constipation(12.1% vs. 24.6%), mild and serious stress urinary incontinence(SUI) post-operative(P<0.001; P=0.014), and proportion of Female Sexual Functioning Index(FSFI) total score <26.55 post-operative(P<0.001) of the LH group were significantly less than those of AH group. There wereno significant differences in OT(106.5±34.5 vs. 106.2±40.3 min) between the two groups.Conclusions: LH is a safe and efficient operation for improving patients' long-term quality of life(Qo L), and LH is a cost-effectiveness procedure for treating benign gynecological disease. LH is superior to AH due to reduced EBL, reduced post-operative pain and earlier passing flatus. | Hongying He Zhijun Yang Dingyuan Zeng Jiangtao Fan Xiaoxia Hu Yuan Ye Hua Bai YanmingJiang Zhong Lin Zhiying Lei Xinlin Li Lian Li Jinghua Gan Ying Lan Xiongzhi Tang Danxia Wang Junsong Jiang Xiaoyan Wu Meiying Li Xiaoqing Ren Xiaomin Yang Mei Liu Qinmei Wang Fuyan jiang Li Li | 2016 | Chinese Journal of Cancer Research2016，28，2： | 6 |
| 17 | Ultra-deep desulfurization by reactive adsorption desulfurization on copper-based catalysts显示文摘In this paper,a novel copper-based catalyst for FCC gasoline improving the ability of removal the sulfur and avoiding the loss of the octane number from olefin saturation by reactive adsorption desulfurization(RADS) was investigated.The series of Cu/Zn O-Al_2 O_3 catalysts were characterized by X-ray powder diffraction(XRD),N_2 adsorption analysis and temperature-programmed reduction(TPR) studies,X-ray photoelectron spectroscopy(XPS),scanning electron microscope(SEM) and transmission electron microscopy(TEM).The experiment results showed that the catalysts had an optimum desulfurization ability with copper loading 6 wt%,which the sulfur contents of product decreased less than 10 μg/g and olefin contents decreased from 16.19% to 14.14% for the long period operation.The appropriate Cu loading content could lead to the high active and low apparent activation energy(E_a).Therefore,the Cu-based catalyst may become a novel catalyst for second-generation for reactive adsorption desulfurization,which achieves the high desulfurization active and low olefins saturation to satisfy the upgrading the product. | Yaqing Liu Hongying Wang Jinchong Zhao Yunqi Liu Chenguang Liu | 2019 | Journal of Energy Chemistry2019，28，2： | 6 |
| 18 | A Novel System for Moving Object Detection Using Bionic Compound Eyes显示文摘 | Huabo Sun Haimeng Zhao Peter Mooney Hongying Zhao Daping Liu Lei Yan | 2011 | Journal of Bionic Engineering2011，8，3： | 6 |
| 19 | Amphiphilic dextran/magnetite nanocomposites as magnetic resonance imaging probes显示文摘Superparamagnetic iron oxide (SPIO) nanoparticles are effective contrast agents for enhancement of magnetic resonance imaging at the tissue, cellular or even molecular levels. High quality SPIO nanoparticles can be synthesized in the organic phase but need to be transferred into water before any biomedical applications. In this study, amphiphilic poly(ε-caprolactone) grafted dextran (Dex-g-PCL) was used as carriers for particle encapsulation and stabilization in the aqueous phase. Multiple SPIO nanoparticles were self-assembled together with the help of Dex-g-PCL during phase transfer from chloroform to water, and diameters of Dex-g-PCL/SPIO nanocomposites were (64 ± 22) nm through dynamic light scattering measurement. These nanocomposites were superparamagnetic at 300 K with saturated magnetization of 88 emu/g Fe. In the magnetic field of 1.5 T, Dex-g-PCL/SPIO nanocomposites had a T2 relaxivity of 363 Fe mL·mol-1·s-1. This unique nanocomposite brought significant mouse liver contrast with signal intensity changes of -60% at 5 min after intravenous administration. However, uptake of Dex-g-PCL/SPIO nanocomposites in liver reticuloendothelial cells (Kupffer cells) did not immediately happen at shorter time points (<4 h) as verified by histology studies, and it was evident that more iron staining would be located in Kupffer cells 24 h after contrast agent administration. After 24 h and 10 d, the signal intensities (SI) gradually recovered, and SI changes were -44% and -31%, respectively. From our observation, the time window for enhanced-MRI could last at least 12 days and totally recovered after 16 days. This novel sensitive MRI contrast agent may find potential applications in discovering small liver lesions such as early tumor diagnosis. | WANG QiaoYing SU HongYing XIA ChunChao SUN JiaYu LIU Chen WANG ZhiYong GONG QiYong SONG Bin GAO FaBao AI Hua GU ZhongWei | 2009 | Chinese Science Bulletin2009，54，17： | 5 |
| 20 | Rational development of a human antibody cocktail that deploys multiple functions to confer Pan-SARS-CoVs protection显示文摘Structural principles underlying the composition and synergistic mechanisms of protective monoclonal antibody cocktails are poorly defined.Here,we exploited antibody cooperativity to develop a therapeutic antibody cocktail against SARS-CoV-2.On the basis of our previously identified humanized cross-neutralizing antibody H014,we systematically an a lyzed a fully human n aive antibody library and rationally identified a potent neutralizing antibody partner,P17,which confers effective protection in animal model.Cryo-EM studies dissected the nature of the P17 epitope,which is SARS-CoV-2 specific and distinctly different from that of HOI4.High-resolution structure of the SARS-CoV-2 spike in complex with HOM and P17,together with functional investigations revealed that in a two-antibody cocktail,synergistic neutralization was achieved by S1 shielding and conformational locking,thereby blocking receptor attachment and viral membrane fusion,conferring high potency as well as robustness against viral mutation escape.Furthermore,cluster analysis identified a hypothetical 3rd antibody partner for further reinforcing the cocktail as pan-SARS-CoVs therapeutics. | Hangping Yao Yao Sun Yong-Qiang Deng Nan Wang Yongcong Tan Na-Na Zhang Xiao-Feng Li Chao Kong Yan-Peng Xuc Qi Chen Tian-Shu Cao Hui Zhao Xintian Yan Lei Cao Zhe Lv Dandan Zhu Rui Feng Nanping Wu Wenhai Zhang Yuhao Hu Keda Chen Rong-Rong Zhang Qingyu Lv Shihui Sun Yunhua Zhou Run Yan Guan Yang Xinglu Chanjuan Liu Xiangyun Lu Linfang Cheng Hongying Qiu Xing-Yao Huang Tianhao Weng Danrong Shi Weidong Jiang Junbin Shao Lei Wang Jie Zhang Tao Jiang Guojun Lang Cheng-Feng Qinc Lanjuan Li Xiangxi Wang | 2021 | Cell Research2021，31，1： | 5 |
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