|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | De Novo Design of Polymeric Carrier to Photothermally Release Singlet Oxygen for Hypoxic Tumor Treatment显示文摘Intratumoral hypoxia extremely limits the clinic applications of photodynamic therapy(PDT).Endoperoxides allow thermally releasing singlet oxygen(1O_(2))in a defned quantity and ofer promising opportunities for oxygen-independent PDT treatment of hypoxic tumors.However,previous composite systems by combining endoperoxides with photothermal reagents may result in unpredicted side efects and potential harmful impacts during therapy in vivo.Herein,we de novo design an all-in-one polymer carrier,which can photothermally release 1O_(2).Te strategy has been demonstrated to efectively enhance the production of 1O_(2) and realize the photodamage in vitro,especially in hypoxic environment.Additionally,the polymer carrier accumulates into tumor afer intravenous injection via the enhanced permeation and retention efects and accelerates the oxygen-independent generation of 1O_(2) in tumors.Te oxidative damage results in good inhibitory efect on tumor growth.Realization of the strategy in vivo paves a new way to construct photothermal-triggered oxygen-independent therapeutic platform for clinical applications. | Tianci Huang Menglong Zhao Qi Yu Zheng Feng Mingjuan Xie Shujuan Liu Kenneth Yin Zhang Qiang Zhao Wei Huang | 2019 | Research2019，，1： | 6 |
| 2 | Multiple sulfur and oxygen isotope compositions in Beijing aerosol显示文摘Multiple sulfur isotopes(32S, 33 S, 34 S, 36S) and oxygen isotopes(16O, 18O) in Beijing aerosols were measured with MAT-253 isotope mass spectrometer. The δ34S values of Beijing aerosol samples range from 1.68‰ to 12.57‰ with an average value of 5.86‰, indicating that the major sulfur source is from direct emission during coal combustion. The δ18O values vary from 5.29‰ to 9.02‰ with an average value of 5.17‰, revealing that the sulfate in Beijing aerosols is mainly composed of the secondary sulfate. The main heterogeneous oxidation of SO2 in atmosphere is related to H2O2 in July and August, whereas H2O2 oxidation and Fe3+ catalytic oxidation with SO2 exist simultaneously in September and October. Remarkable sulfur isotope mass-independent fractionation effect is found in Beijing aerosols, which is commonly attributed to the photochemical oxidation of SO2 in the stratosphere. In addition, thermochemical reactions of sulfur-bearing compounds might be also a source of sulfur isotope anomalies based on the correlation between ?33S and CAPE. | GUO ZhaoBing WU MengLong LIU FengLing WEI Ying LI DongFang | 2014 | Science China Earth Sciences2014，57，11： | 5 |
| 3 | BIK1 cooperates with BAK1 to regulate constitutive immunity and cell death in Arabidopsiss显示文摘In Arabidopsis,both the membrane-anchored receptor-like kinase(RLK) BAK1 and the receptor-like cytoplasmic kinase(RLCK) BIK1 are important mediators of transmembrane signal transduction that regulate plant development and immunity.However,little attention has been paid to their genetic association.This study found the bak1 bik1 double mutant of Arabidopsis displayed a severe dwarfism phenotype due to constitutive immunity and cell death in developing plants.These data suggest that BIK1 cooperates with BAK1 to regulate constitutive immunity and cell death. | Jun Liu Sufen Chen Lijuan Chen Qi Zhou Menglong Wang Dongru Feng Jian-Feng Li Jinfa Wang Hong-Bin Wang Bing Liu | 2017 | Journal of Integrative Plant Biology2017，59，4： | 2 |
| 4 | Design of intelligent vehicle system basedon embedded ARM显示文摘 | LIU Wenkai XU Aigong WU Menglong | 2014 | WITPress2014，51，： | 1 |
| 5 | Analytical Modeling of Lamb Wave Propagation in Composite Laminate Bonded with Piezoelectric Actuator Based on Mindlin Plate Theory 显示文摘 | Zhang Xiaoyue Yuan Shenfang Liu Menglong | 2012 | Journal of Vibroengineering2012，14，4： | 1 |
| 6 | Esti- mating the 显示文摘 | Menglong Yang Yiguang Liu Zhisheng You | 2011 | Neurocomputing2011，74，17： | 1 |
| 7 | A single mutation underlying phenotypic convergence for hypoxia adaptation on the Qinghai-Tibetan Plateau显示文摘Dear Editor,The Qinghai-Tibet Plateau(QTP)is the highest and largest plateau in the world;its altitude exceeds 4500 m on average,posing great physiological challenges such as severe hypoxia for endemic wild mammals on the plateau.1 To cope with such a harsh environment,the phylogenetically distant QTP endemic mammals have independently evolved similar morphological and physiological traits. | Donqming Xu Cuiping Yang Qiushuo Shen Shengkai Pan Zhen Liu Tongzuo Zhang Xin Zhou Menglong Lei Peng Chen Hui Yang Tao Zhang Yuanting Guo Xiangjiang Zhan Yongbin Chen Peng Shi | 2021 | Cell Research2021，31，9： | 1 |
| 8 | Recent progress in electrospun nanofibers and their applications in heavy metal wastewater treatment显示文摘Novel adsorbents with a simple preparation process and large capacity for removing highly toxic and nondegradable heavy metals from water have drawn the attention of researchers.Electrospun nanofiber membranes usually have the advantages of large specific surface areas and high porosity and allowing flexible control and easy functionalization.These membranes show remarkable application potential in the field of heavy metal wastewater treatment.In this paper,the electrospinning technologies,process types,and the structures and types of nanofibers that can be prepared are reviewed,and the relationships among process,structure and properties are discussed.On one hand,based on the different components of electrospun nanofibers,the use of organic,inorganic and organic−inorganic nanofiber membrane adsorbents in heavy metal wastewater treatment are introduced,and their advantages and future development are summarized and prospected.On the other hand,based on the microstructure and overall structure of the nanofiber membrane,the recent progresses of electrospun functional membranes for heavy metal removal are reviewed,and the advantages of different structures for applications are concluded.Overall,this study lays the foundation for future research aiming to provide more novel structured adsorbents. | Xizi Xu He Lv Mingxin Zhang Menglong Wang Yangjian Zhou Yanan Liu Deng-Guang Yu | 2023 | Frontiers of Chemical Science and Engineering2023，17，3： | 1 |
| 9 | Microcellular foamed polyamide 6/carbon nanotube composites withsuperior electromagnetic wave absorption显示文摘Electromagnetic (EM) wave pollution causing damage to precision equipment and threatening thehealth of living organisms has attracted considerable attention. Herein, promising microcellular foamedpolyamide 6 (PA6)/carbon nanotube (CNT) composites for highly efficient EM wave absorption were successfully fabricated using supercritical CO_(2) foaming. Nanocomposites foams with a void fraction rangingfrom 38.7% to 85.1% were achieved, providing a platform to assess the correlation of the electrical conductivity, the dielectric permittivity and the EM wave absorption properties with porosity. Notably, theFoam-257.5C sample with a void fraction of 38.7% exhibited outstanding EM wave absorption characteristics at a thickness of only 1.59 mm and an ultra-low reflection loss value of -55.3 dB (99.9997% wave absorption). Most importantly, the effective absorption bandwidth (EAB) of the Foam-257.5C sample couldcover the entire Ku band (12.4–18 GHz) by slightly adjusting the thickness from 1.20 to 1.60 mm. Thesuperior EM wave absorption performance of the Foam-257.5C sample was attributed to multiple reflections and scattering at the solid-gas interfaces, favorable impedance matching due to the existence ofa large polymer-air interface area, conductive loss near the interfaces and interfacial polarization. Thus,this study offers an eco-friendly, simple and versatile methodology to develop high-efficiency, flexiblepolymer-based EM wave absorbents. | Menglong Xu Linfeng Wei Li Ma Jiawei Lu Tao Liu Ling Zhang Ling Zhao Chul B.Park | 2022 | Journal of Materials Science & Technology2022，，22： | 1 |
| 10 | Detection of chemical oxygen demand in water based on UV absorption spectroscopy and PSO-LSSVM algorithm显示文摘A method of detecting chemical oxygen demand(COD) of water based on ultraviolet(UV) absorption spectra is proposed. The modeling and analysis of the standard samples and the actual water samples are carried out respectively. For the standard solution samples, the univariate linear models based on single wavelengths and the partial least square(PLS) model based on synergy interval partial least square(Si PLS) and moving window partial least square(MWPLS) are established. For the actual water samples, different pre-processing methods are used. Si PLS and MWPLS are used to select the characteristic bands. The least squares support vector machine algorithm optimized by particle swarm optimization(PSO-LSSVM) algorithm is used to establish the prediction model, and the prediction results of various models are compared. The results show that the optimal model is PSO-LSSVM which uses Si PLS to select the characteristic bands of the first derivative spectra(preprocessing method). The determination coefficient of the prediction set is 0.963 1, and the root mean square error of prediction(RMSEP) is 2.225 4 mg/L. PSO-LSSVM algorithm has good prediction performance for the analysis of COD in actual water samples by UV spectra. This paper provides a new design idea for the research and development of water quality detection optical sensor. | ZHOU Kunpeng LIU Zhiyang CONG Menglong MAN Shanxin | 2022 | Optoelectronics Letters2022，18，4： | 1 |
| 11 | Modified Homotopy Methods to Solve Fixed Points of Self-mapping in a Broader Class of Nonconvex Sets 显示文摘 | SU Menglong LIU Zhenxin | 2008 | Appl Numer Math2008，58，3： | 1 |
| 12 | Hypervelocity impact induced shock acoustic emission waves for quantitative damage evaluation using in situ miniaturized piezoelectric sensor network显示文摘Manmade debris and natural meteoroids, travelling in the Low Earth Orbit at a speed of several kilometers per second, pose a severe safety concern to the spacecraft in service through the HyperVelocity Impact(HVI). To address this issue, an investigation of shock Acoustic Emission(AE) waves induced by HVI to a downscaled two-layer Whipple shielding structure is performed,to realize a quantitative damage evaluation. Firstly a hybrid numerical model integrating smoothparticle hydrodynamics and finite element is built to obtain the wave response. The projectiles, with various impact velocities and directions, are modelled to impact the shielding structure with different thicknesses. Then experimental validation is carried out with built-in miniaturized piezoelectric sensors to in situ sense the HVI-induced AE waves. A quantitative agreement is obtained between numerical and experimental results, demonstrating the correctness of the hybrid model and facilitating the explanation of obtained AE signals in experiment. Based on the understanding of HVI-induced wave components, assessment of the damage severity, i.e., whether the outer shielding layer is perforated or not, is performed using the energy ratio between the regions of ‘‘high frequency' and ‘‘low frequency' in the acquired AE signals. Lastly, the direct-arrival fundamentalsymmetric wave mode is isolated from each sensing signal to be input into an enhanced delay-andsum algorithm, which visualizes HVI spots accurately and instantaneously with different sensor network configuration. All these works demonstrate the potential of quantitative, in situ, and real time HVI monitoring using miniaturized piezoelectric sensor network. | Menglong LIU Qiang WANG Qingming ZHANG Renrong LONG Fangsen CUI Zhongqing SU | 2019 | Chinese Journal of Aeronautics2019，32，5： | 1 |
| 13 | RP-NBSR: A Novel Network Attack Detection Model Based on Machine Learning显示文摘The rapid progress of the Internet has exposed networks to an increasednumber of threats. Intrusion detection technology can effectively protect networksecurity against malicious attacks. In this paper, we propose a ReliefF-P-NaiveBayes and softmax regression (RP-NBSR) model based on machine learningfor network attack detection to improve the false detection rate and F1 score ofunknown intrusion behavior. In the proposed model, the Pearson correlation coef-ficient is introduced to compensate for deficiencies in correlation analysis betweenfeatures by the ReliefF feature selection algorithm, and a ReliefF-Pearson correlation coefficient (ReliefF-P) algorithm is proposed. Then, the Relief-P algorithm isused to preprocess the UNSW-NB15 dataset to remove irrelevant features andobtain a new feature subset. Finally, naïve Bayes and softmax regression (NBSR)classifier is constructed by cascading the naïve Bayes classifier and softmaxregression classifier, and an attack detection model based on RP-NBSR is established. The experimental results on the UNSW-NB15 dataset show that the attackdetection model based on RP-NBSR has a lower false detection rate and higherF1 score than other detection models. | Zihao Shen Hui Wang Kun Liu Peiqian Liu Menglong Ba MengYao Zhao | 2021 | Computer Systems Science & Engineering2021，37，4： | 0 |
| 14 | Chemically bonded multi-nanolayer inorganic aerogel with a record-low thermal conductivity in a vacuum显示文摘Inorganic aerogels have exhibited many superior characteristics with extensive applications,but are still plagued by a nearly century-old tradeoff between their mechanical and thermal properties.When reducing thermal conductivity by ultralow density,inorganic aerogels generally suffer from large fragility due to their brittle nature or weak joint crosslinking,while enhancing the mechanical robustness by material design and structural engineering,they easily sacrifice thermal insulation and stability.Here,we report a chemically bonded multi-nanolayer design and synthesis of a graphene/amorphous boron nitride aerogel to address this typical tradeoff to further enhance mechanical and thermal properties.Attributed to the chemically bonded interface and coupled toughening effect,our aerogels display a low density of 0.8 mg cm-3 with ultrahigh flexibility(elastic compressive strain up to 99%and bending strain up to 90%),and exceptional thermostability(strength degradation<3%after sharp thermal shocks),as well as the lowest thermal conductivities in a vacuum(only 1.57 mW m-1 K-1 at room temperature and 10.39 mW m-1 K-1 at500℃)among solid materials to date.This unique combination of mechanical and thermal properties offers an attractive material system for thermal superinsulation at extreme conditions. | Hongxuan Yu Menglin Li Yuanpeng Deng Shubin Fu Jingran Guo Han Zhao Jianing Zhang Shixuan Dang Pengyu Zhang Jian Zhou Dizhou Liu Duola Wang Chuanwei Zhang Menglong Hao Xiang Xu | 2023 | National Science Review2023，10，10： | 0 |
| 15 | Analysis on influencing factors of detecting chemical oxygen demand in water by three-dimensional spectroscopy显示文摘This paper focuses on the standard chemical oxygen demand(COD)liquid and studies the impact of pH,nitrite nitrogen,nitrate nitrogen,heavy metals,salinity,and other factors on fluorescence intensity and fluorescence peak positions during the detection of COD in water using fluorescence spectrometry.The influence mechanisms of different environmental factors on fluorescence spectra are also analyzed.Results indicate that pH value affects the fluorescence emission wavelength(Em),resulting in a red shift from 1.5 to 7.2,and a blue shift from 7.2 to 12.3.Nitrate nitrogen can react with organic matter in water to form nitro compounds,leading to a decrease in fluorescence intensity.Salinity has a negligible effect on T1 peak but a relatively large effect on T2 peak.Heavy metal ion concentration has a significant impact on T2 peak,while T1 peak position shifts with an increase in heavy metal ions.This study aims to explore the factors that can impact the detection of COD in water using three-dimensional fluorescence spectrometry,providing references to improve accuracy and practicability for COD detection based on three-dimensional fluorescence spectrometry. | ZHOU Kunpeng LIU Zhiyang CONG Menglong MAN Shanxin | 2024 | Optoelectronics Letters2024，20，1： | 0 |
| 16 | Grapevine plantlets respond to different monochromatic lights by tuning photosynthesis and carbon allocation显示文摘The quality of planting materials is the foundation for productivity,longevity,and berry quality of perennial grapevines with a long lifespan.Manipulating the nursery light spectrum may speed up the production of healthy and high-quality planting vines but the underlying mechanisms remain elusive.Herein,the effects of different monochromatic lights(green,blue,and red)on grapevine growth,leaf photosynthesis,whole-plant carbon allocation,and transcriptome reprograming were investigated with white light as control.Results showed that blue and red lights were favorable for plantlet growth in comparison with white light.Blue light repressed excessive growth,significantly increased the maximum net photosynthetic rate(Pn)of leaves by 39.58%and leaf specific weight by 38.29%.Red light increased the dry weight of the stem by 53.60%,the starch content of the leaf by 53.63%,and the sucrose content of the stem by 230%.Green light reduced all photosynthetic indexes of the grape plantlet.Photosynthetic photon flux density(PPFD)/Ci–Pn curves indicated that blue light affected photosynthetic rate depending on the light intensity and CO2 concentration.RNA-seq analysis of different organs(leaf,stem,and root)revealed a systematic transcriptome remodeling and VvCOP1(CONSTITUTIVELY PHOTOMORPHOGENIC 1),VvHY5(ELONGATED HYPOCOTYL5),VvHYH(HY5 HOMOLOG),VvELIP(early light-induced protein)and VvPIF3(PHYTOCHROME INTERACTING FACTOR 3)may play important roles in this shoot-to-root signaling.Furthermore,the correlation network between differential expression genes and physiological traits indicated that VvpsbS(photosystem II subunit S),Vvpsb28(photosystem II subunit 28),VvHYH,VvSUS4(sucrose synthase 4),and VvALDA(fructose-bisphosphate aldolase)were pertinent candidate genes in responses to different light qualities.Our results provide a foundation for optimizing the light recipe of grape plantlets and strengthen the understanding of light signaling and carbon metabolism under different monochromatic lights. | Menglong Liu Yan Zhao Peige Fan Junhua Kong Yongjian Wang Xiaobo Xu Meilong Xu Lijun Wang Shaohua Li Zhenchang Liang Wei Duan Zhanwu Dai | 2023 | Horticulture Research2023，10，9： | 0 |
| 17 | Analysis on influencing factors of detecting chemical oxygen demand in water by ultraviolet absorption spectroscopy显示文摘Taking the standard solution and actual water samples as the research object, this paper studies the influence of various environmental factors(temperature, alkalinity(pH), inorganic salt ions and salinity) on the detection of chemical oxygen demand(COD) in water by ultra-violet(UV) spectrometry, analyzes the influence mechanism, and draws relevant conclusions. The results show that the UV absorbance of the COD standard solution and the actual river water samples varies very little with temperature. The value of pH has certain impact on both the standard solution and the actual water samples, but the pH values of the affected experimental samples are in different ranges. The effects of nitrogen salt ions(NO_(2)^(-)and NO_(3)^(-)) on the UV absorption spectra can be eliminated by intercepting the UV spectrum interval less affected for modeling. The influence of salinity values below 35‰ on the UV absorption spectrum of water is mainly concentrated in the spectral band of 200—250 nm, and the influence above 250 nm is very little. This paper provides a preliminary analysis and discussion on the influence mechanism and laws of various environmental factors in the detection of water quality parameters by UV spectrometry, which provides an experimental basis for selecting the optimal test conditions when establishing the COD prediction model. | ZHOU Kunpeng LIU Zhiyang CONG Menglong MAN Shanxin | 2022 | Optoelectronics Letters2022，18，12： | 0 |
| 18 | Encapsulated carbon nanotube array as a thermal interface material compatible with standard electronics packaging显示文摘Vertically aligned carbon nanotubes arrays(VACNTs)are a promising candidate for the thermal interface material(TIM)of next-generation electronic devices due to their attractive thermal and mechanical properties.However,the environment required for synthesizing VACNTs is harsh and severely incompatible with standard device packaging processes.VACNTs’extremely low in-plane thermal conductivity also limits its performance for cooling hot spots.Here,using a transfer-and-encapsulate strategy,a two-step soldering method is developed to cap both ends of the VACNTs with copper microfoils,forming a standalone Cu-VACNTs-Cu sandwich TIM and avoiding the need to directly grow VACNTs on chip die.This new TIM is fully compatible with standard packaging,with excellent flexibility and high thermal conductivities in both in-plane and through-plane directions.The mechanical compliance behavior and mechanism,which are critical for TIM applications,are investigated in depth using in situ nanoindentation.The thermal performance is further verified in an actual light emitting diode(LED)cooling experiment,demonstrating low thermal resistance,good reliability,and achieving a 17℃ temperature reduction compared with state-of-the-art commercial TIMs.This study provides a viable solution to VACNTs’longstanding problem in device integration and free-end contact resistance,bringing it much closer to application and solving the critical thermal bottleneck in next-generation electronics. | Ruixiang Bai Yangbing Wei Jiyuan Xu Xiaobo Li Menglin Li Ziwen Zou Xinyan Huang Chengyu Liu Yiwei Sun Menglong Hao | 2023 | Nano Research2023，16，8： | 0 |
| 19 | A ratiometric fluorescent sensor for tracking Cu(Ⅰ) fluctuation in endoplasmic reticulum显示文摘A two-photon ratiometric fluorescent sensor for Cu^+ in endoplasmic reticulum(ER), CNSB, was developed via coumarin/ASBD integration based on FRET mechanism. In solution, CNSB shows reversible, highly-specific ratiometric response to Cu^+ .Moreover, CNSB exhibits suitable K_d value, suggesting the possibility of detecting Cu^+ in the living cells. The probe can enter the MCF-7 cells easily and specifically locates in the ER. The highly specific ratiometric response of CNSB toward Cu^+ in MCF-7 cells provides the sensor the capacity to visualize both exogenous and endogenous Cu^+ in the ER via fluorescence imaging.Next, CNSB was utilized to detect the fluctuation and distribution of Cu^+ under ER stress in MCF-7 cells, which confirmed directly the relationship between Cu^+ enhancement and ER stress. Meanwhile, the two-photon ability of coumarin facilitated the sensor to visualize Cu^+ fluctuation via two-photon fluorescence imaging. In addition, the spatial distribution of Cu^+ in the heart slice of the 14-day-old rat was demonstrated using CNSB. This study demonstrates the promising potential of CNSB in clarifying the Cu^+ -dependent signaling in the ER stress-related diseases. | Jungu Guo Hao Yuan Yuncong Chen Zhongyan Chen Menglong Zhao Liang Zou Yi Liu Zhipeng Liu Qiang Zhao Zijian Guo Weijiang He | 2019 | Science China Chemistry2019，62，4： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员