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| 1 | Surface Nanocrystallization (SNC) of Metallic Materials-Presentation of the Concept behind a New Approach显示文摘In this paper, a concept of surface nanocrystallization (SNC) of metallic materials is introduced.Three types of SNC processes are classified. Different SNC mechanisms and possible techniques for SNC are discussed with emphasis on mechanically induced surface self-nanocrystallization.Further development and prospects are addressed with respect to the properties and behaviors of the materials with a nanocrystalline surface. Enhancement of the behavior of the engineering materials by means of the SNC technology and its industrial application possibilities are analyzed. | Lu, K Lu, J | 1999 | Journal of Materials Science & Technology1999，15，3： | 296 |
| 2 | Out of southern East Asia: the natural history of domestic dogs across the world显示文摘 | Guo-Dong Wang Weiwei Zhai He-Chuan Yang Lu Wang LioZhong Yan-Hu Liu Ruo-Xi Fan Ting-Ting Yin Chun-Ling Zhu Andrei D Poyarkov David M Irwin Marjo K Hytonen Hannes Lohi Chung-I Wu Peter Savolainen Ya-Ping Zhang | 2016 | Cell Research2016，26，1： | 16 |
| 3 | Identification of an ideal adjuvant for receptor-binding domain-based subunit vaccines against Middle East respiratory syndrome coronavirus显示文摘 | Naru Zhang Rudragouda Channappanavar Cuiqing Ma Lili Wang Jian Tang Tania Garron Xinrong Tao Sumaiya Tasneem Lu Lu Chien-Te K Tseng Yusen Zhou Stanley Perlman Shibo Jiang Lanying Du | 2016 | Cellular & Molecular Immunology2016，13，2： | 12 |
| 4 | Serum positive cagA in patients with non-ulcer dyspepsia and peptic ulcer disease from two centers in different regions of Turkey显示文摘AIM: To investigate and compare frequencies of serum positive cagA in patients from two separate regions of Turkey who were grouped according to the presence of peptic ulcer disease or non-ulcer dyspepsia.METHODS: One hundred and eighty Helicobacter pyloripositive patients with peptic ulcer disease or non-ulcer dyspepsia were included in the study. One hundred and fourteen patients had non-ulcer dyspepsia and 66 had peptic ulcer disease (32 with gastric ulcers and/or erosions and 34with duodenal ulcers). Each patient was tested for serum antibody to H. pylori cagA protein by enzyme immunoassay.RESULTS: The total frequency of serum positive cagA in the study group was 97.2 %. The rates in the patients with peptic ulcers and in those with non-ulcer dyspepsia were 100% and 95.6%, respectively. These results were similar to those reported in Asian studies, but higher than those that have been noted in other studies from Turkey and Western countries.CONCLUSION: The high rates of serum positive cagA in these patients with peptic ulcer disease and non-ulcer dyspepsia were similar to results reported in Asia. The fact that there was high seroum prevalence regardless of ulcer status suggests that factors other than cagA might be responsible for ulceration or other types of severe pathology in H. pylori-positive individuals. | Ender Serin Uur Yilmaz Ganiye Künefeci Birol zer Yüksel Gümürdülü Mustafa Gülü Fazilet Kayaseluk Sedat Boyaciolu | 2003 | World Journal of Gastroenterology2003，9，4： | 10 |
| 5 | Multilinear Singular and Fractional Integrals显示文摘In this paper, we treat a class of non-standard commutators with higher order remaindersin the Lipschitz spaces and give (L^p, L^q), (H^p, L^q) boundedness and the boundedness in the Triebel-Lizorkin spaces. Our results give simplified proofs of the recent works by Chen, and extend his result. | Yong DING Shan Zhen LU Kz YABUTA | 2006 | Acta Mathematica Sinica,English Series2006，22，2： | 8 |
| 6 | National, regional, and global trends in fasting plasma glucose and diabetes prevalence since 1980: systematic analysis of health examination surveys and epidemiological studies with 370 country-years and 2·7 million participants显示文摘 | Goodarz Danaei Mariel M Finucane Yuan Lu Gitanjali M Singh Melanie J Cowan Christopher J Paciorek John K Lin Farshad Farzadfar Young-Ho Khang Gretchen A Stevens Mayuree Rao Mohammed K Ali Leanne M Riley Carolyn A Robinson Majid Ezzati | 2011 | The Lancet2011，，9785： | 6 |
| 7 | The causal sequence investigation of the ring current ion-flux increasing and the magnetotail ion injection during a major storm显示文摘全面记录在 NUADU 仪器在主要磁性的暴风雨期间在 2005 年 5 月 15 日在 TC-2 上记录的戒指水流活动的 ENA 数据是可得到的(它合并了一系列 substorms ) 。在时间的分辨率在 5081 和 81158 keV 与相比的精力范围从 ENA 数据导出的 4-min 的离子流动在 situ ,粒子流动在 LANL-01 上由 LANL-SOPA 仪器测量了, LANL-02 , LANL-97 ,并且 LANL-84 (环绕的一系列地球同步的卫星在~的赤道的飞机 6.6 R E )。另外,磁场在 GOES-10 和 GOES-12 上由 magetometers 同时测量了(它也是地球同步的卫星) 与粒子数据相比。在戒指水流的离子流动在在 substorms 而非在向地的指导 dipolarization 事件以后的生长阶段拉长的地磁气的地 tailward 期间被提高,这被表明。这观察,它质问戒指水流粒子被注射的存在概念从 magnetotail 追随者 dipolarization 事件向地,用很多磁性的暴风雨事件要求进一步的调查。 | LU Li S MCKENNA-LAWLOR CAO JinBin K KUDELA J BALAZ | 2016 | Science China Earth Sciences2016，59，1： | 4 |
| 8 | Recurrent carpal tunnel syndrome: Evaluation and treatment of the possible causes显示文摘AIM To investigate the causes of the recurrent carpal tunnel syndrome(CTS) and implemented surgical interventions.METHODS Four hundred and eighty-seven patients, who were diagnosed with CTS and underwent surgical intervention between October 2016 and September 2007, were evaluated in this retrospective study. The age, gender, physical evaluation findings, electrophysiological examination reports and implemented surgical treatment methods were analyzed.RESULTS Thirty-nine of the cases were operated due to recurrent CTS. Further examination of the patients with recurrent CTS revealed that ten cases had diabetic polyneuropathy, three cases had hypothyroidism, two cases had rheumatoid arthritis and one case had systemic amyloidosis. Postoperative electromyography confirmed the neuropathy was due to systemic diseases. The remaining 23 patients with recurrent CTS did not have any systemic disease and all of them had applied previously to another health center. CONCLUSION We concluded that the recurrence rates in CTS might be decreased with exploration and incision of the entire transverse ligament. Damage to the motor and sensory branches of the median nerve could be avoided with an incision on the ulnar side. | Ahmet Ero?lu Enes Sar? Ali K?van? Topuz Hakan ?im?ek Serhat Pusat | 2018 | World Journal of Clinical Cases2018，6，10： | 4 |
| 9 | Lack of hepcidin expression attenuates steatosis and causesfibrosis in the liver显示文摘AIM: To investigate the role of key iron-regulatory protein, hepcidin in non-alcoholic fatty liver disease(NAFLD). METHODS: Hepcidin(Hamp1) knockout and floxed control mice were administered a high fat and high sucrose(HFS) or a regular control diet for 3 or 7 mo. Steatosis, triglycerides, fibrosis, protein and gene expression in mice livers were determined by histological and biochemical techniques, western blotting and realtime polymerase chain reaction. RESULTS: Knockout mice exhibited hepatic iron accumulation. Despite similar weight gains, HFS feeding induced hepatomegaly in floxed, but not knockout, mice. The livers of floxed mice exhibited higher levels of steatosis, triglycerides and c-Jun N-terminal kinase(JNK) phosphorylation than knockout mice. In contrast, a significant increase in fibrosis was observed in knockout mice livers within 3 mo of HFS administration. The hepatic gene expression levels of sterol regulatoryelement-binding protein-1c and fat-specific protein-27, but not peroxisome proliferator-activated receptoralpha or microsomal triglyceride transfer protein, were attenuated in HFS-fed knockout mice. Knockout mice fed with regular diet displayed increased carnitine palmitoyltransferase-1a and phosphoenolpyruvate carboxykinase-1 but decreased glucose-6-phosphatase expression in the liver. In summary, attenuated steatosis correlated with decreased expression of lipogenic and lipid storage genes, and JNK phosphorylation. Deletion of Hamp1 alleles per se modulated hepatic expression of beta-oxidation and gluconeogenic genes. CONCLUSION: Lack of hepcidin expression inhibits hepatic lipid accumulation and induces early development of fibrosis following high fat intake. Hepcidin and iron may play a role in the regulation of metabolic pathways in the liver, which has implications for NAFLD pathogenesis. | Sizhao Lu Robert G Bennett Kusum K Kharbanda Duygu Dee Harrison-Findik | 2016 | World Journal of Hepatology2016，8，4： | 3 |
| 10 | Comparison of antioxidant activity of clove ( Eugenia caryophylata Thunb) buds and lavender ( Lavandula stoechas L.)显示文摘 | ìlhami Gül?in ?. Güng?r ?at ?ükrü Beydemir Mahfuz Elmasta? ?. ?rfan Küfrevio?lu | 2004 | Food Chemistry2004，，3： | 3 |
| 11 | Low carbon steel with nanostructured surface layer induced by high-energy shot peening显示文摘 | G Liu S.C Wang X.F Lou J Lu K Lu | 2001 | Scripta Materialia2001，，8： | 3 |
| 12 | Noncontrast-enhanced MRI-based Noninvasive Score for Portal Hypertension(CHESS1802):An International Multicenter Study显示文摘Background and Aims:This study aimed to determine the performance of the non-invasive score using noncontrastenhanced MRI(CHESS-DIS score)for detecting portal hy-pertension in cirrhosis.Methods:In this international multicenter,diagnostic study(ClinicalTrials.gov,NCT03766880),patients with cirrhosis who had hepatic venous pressure gradient(HVPG)measurement and noncontrast-enhanced MRI were prospectively recruited from four university hospitals in China(n=4)and Turkey(n=1)between December 2018 and April 2019.A cohort of patients was retrospectively recruited from a university hospital in Italy between March 2015 and November 2017.After segmentation of the liver on fat-suppressed T1-weighted MRI maps,CHESS-DIS score was calculated automatically by an in-house developed code based on the quantification of liver surface nodularity.Results:A total of 149 patients were included,of which 124 were from four Chinese hospitals(training cohort)and 25 were from two international hospitals(validation cohort).A positive correlation between CHESS-DIS score and HVPG was found with the correlation coefficients of 0.36(p<0.0001)and 0.55(p<0.01)for the training and validation cohorts,respectively.The area under the receiver operating characteristic curve of CHESS-DIS score in detection of clinically significant portal hypertension(CSPH)was 0.81 and 0.9 in the training and validation cohorts,respectively.The intra-class correlation coefficients for assessing the inter-and intra-observer agreement were 0.846 and 0.841,respectively.Conclusions:A non-invasive score using noncontrast-enhanced MRI was developed and proved to be significantly correlated with invasive HVPG.Besides,this score could be used to detect CSPH in patients with cirrhosis. | Yanna Liu Tianyu Tang NecatiÖrmeci Yifei Huang Jitao Wang Xiaoguo Li Zhiwei Li Weimin An Dengxiang Liu Chunqing Zhang Changchun Liu Jinqiang Liu Chuan Liu Guangchuan Wang Cristina Mosconi Alberta Cappelli Antonio Bruno Seray Akçalar EmrecanÇelebioğlu EvrenÜstüner Sadık Bilgiç Zeynep Ellik ÖzgünÖmer Asiller Lei Li Haijun Zhang Ning Kang Dan Xu Ruiling He Yan Wang Yang Bu Ye Gu Shenghong Ju Rita Golfieri Xiaolong Qi | 2021 | Journal of Clinical and Translational Hepatology2021，9，6： | 3 |
| 13 | Determination of penetration depth at high velocity impact using finite element method and artificial neural network tools显示文摘Determination of ballistic performance of an armor solution is a complicated task and evolved significantly with the application of finite element methods(FEM) in this research field.The traditional armor design studies performed with FEM requires sophisticated procedures and intensive computational effort,therefore simpler and accurate numerical approaches are always worthwhile to decrease armor development time.This study aims to apply a hybrid method using FEM simulation and artificial neural network(ANN) analysis to approximate ballistic limit thickness for armor steels.To achieve this objective,a predictive model based on the artificial neural networks is developed to determine ballistic resistance of high hardness armor steels against 7.62 mm armor piercing ammunition.In this methodology,the FEM simulations are used to create training cases for Multilayer Perceptron(MLP) three layer networks.In order to validate FE simulation methodology,ballistic shot tests on 20 mm thickness target were performed according to standard Stanag 4569.Afterwards,the successfully trained ANN(s) is used to predict the ballistic limit thickness of 500 HB high hardness steel armor.Results show that even with limited number of data,FEM-ANN approach can be used to predict ballistic penetration depth with adequate accuracy. | Nam?k KILI? Blent EKICI Selim HARTOMACIOG LU | 2015 | Defence Technology(防务技术)2015，11，2： | 3 |
| 14 | Microstructure and evolution of mechanically-induced ultrafine grain in surface layer of AL-alloy subjected to USSP显示文摘 | X Wu N Tao Y Hong B Xu J Lu K Lu | 2002 | Acta Materialia2002，，8： | 3 |
| 15 | Surface nanocrystallization of iron induced by ultrasonic shot peening显示文摘 | N.R Tao M.L Sui J Lu K Lua | 1999 | Nanostructured Materials1999，，4： | 3 |
| 16 | Novel role of STAT3 in microglia-dependent neuroinflammation after experimental subarachnoid haemorrhage显示文摘Background and purpose Signal transducer and activator of transcription 3(STAT3)may contribute to the proinflammation in the central nervous system diseases by modulating the microglial responses.Thus,this study was intended to investigate the effect of STAT3 on microglia-dependent neuroinflammation and functional outcome after experimental subarachnoid haemorrhage(SAH).Methods The SAH model was established by endovascular perforation in the mouse.Real-time PCR(RtPCR)and western blot were used to examine the dynamic STAT3 signalling pathway responses after SAH.To clarify the role of the STAT3 signalling pathway in the microglia-dependent neuroinflammation after SAH,the microglia-specific STAT3 knockout(KO)mice were generated by the Cre-LoxP system.The neurological functions were assessed by Catwalk and Morris water maze tests.Neuronal loss after SAH was determined by immunohistochemistry staining.Microglial polarisation status after STAT3 KO was then examined by RtPCR and immunofluorescence.Results The STAT3 and Janus kinase-signal transducer 2 activated immediately with the upregulation and phosphorylation after SAH.Downstream factors and related mediators altered dynamically and accordingly.Microglial STAT3 deletion ameliorated the neurological impairment and alleviated the early neuronal loss after SAH.To investigate the underlying mechanism,we examined the microglial reaction after STAT3 KO.STAT3 deletion reversed the increase of microglia after SAH.Loss of STAT3 triggered the early morphological changes of microglia and primed microglia from M1 to M2 polarisation.Functionally,microglial STAT3 deletion suppressed the SAH-induced proinflammation and promoted the anti-inflammation in the early phase.Conclusions STAT3 is closely related to the microglial polarisation transition and modulation of microglia-dependent neuroinflammation.Microglial STAT3 deletion improved neurological function and neuronal survival probably through promoting M2 polarisation and anti-inflammatory responses after SAH.STAT3 may serve as a promising therapeutic target to alleviate early brain injury after SAH. | Zhiyuan Vera Zheng Junfan Chen Hao Lyu Sin Yu Erica Lam Gang Lu Wai Yee Chan George K C Wong | 2022 | Stroke & Vascular Neurology2022，7，1： | 3 |
| 17 | Preparation and Evaluation of Zidovudine-loaded Sustained-release Microsuheres显示文摘 | Abu-lzza K A Garcia-Contreras L Lu D R | 1996 | J Pharm Sci1996，85，6： | 3 |
| 18 | Recent advances in polymer composites tribology显示文摘 | Friedrich K Lu Z Hager A M | 1995 | Wear1995，190，： | 2 |
| 19 | 查看详情显示文摘 | W S Duan K P Lu J B Zhao | | 0，，： | 2 |
| 20 | National, regional, and global trends in fasting plasma glucose and diabetes prevalence since 1980: systematic analysis of health examination surveys and epidemiological studies with 370 country-years and 2·7 million participants显示文摘 | Goodarz Danaei Mariel M Finucane Yuan Lu Gitanjali M Singh Melanie J Cowan Christopher J Paciorek John K Lin Farshad Farzadfar Young-Ho Khang Gretchen A Stevens Mayuree Rao Mohammed K Ali Leanne M Riley Carolyn A Robinson Majid Ezzati | 2011 | The Lancet2011，，9785： | 2 |
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