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| 1 | PHF8 is a histone H3K9me2 demethylase regulating rRNA synthesis显示文摘histone H3 离氨酸 9 的 Dimethylation (H3K9me2 ) 是与抄写压抑联系的一个重要 epigenetic 标记。这里,我们识别了 PHF8, JmjC-domain-containing 蛋白质,为这个镇压标记特定的 histone demethylase。Recombinant 全身的野类型蛋白质能把 methylation 从 H3K9me2 移开,但是到丙氨酸 H247A 的保存 histidine 的变化废除 demethylase 活动。Overexpressed 外长的 PHF8 是 colocalized, B23 染色。内长的 PHF8 也是有 B23 和 fibrillarin 的 colocalized,二生长得很好的核蛋白质,建议那 PHF8 在核是局部性的并且可以调整 rRNA 抄写。确实, PHF8 跳了到 rDNA 基因的倡导者区域。减少的 PHF8 击倒 rRNA 的表示,和基因的 overexpression 导致了 rRNA 的 upregulation 抄本。附随地, H3K9me2 水平在 PHF8 击倒的房间在 rDNA 基因的倡导者区域被提高并且当野类型然而并非催化地不活跃的 H247A 变异的 PHF8 是 overexpressed 时,显著地减少了。因此,我们的学习为调整 rRNA 抄写的 H3K9me2 识别了 histone demethylase。 | Ziqi Zhu Yanru Wang Xia Li Yiqin Wang Longyong Xu Xiang Wang Tianliang Sun Xiaobin Dong Lulu Chen Hailei Mao Yi Yu Jingsong Li Pin Adele Chen Charlie Degui Chen | 2010 | Cell Research2010，20，7： | 7 |
| 2 | Efficacy of folic acid supplementation in stroke prevention: a meta-analysis显示文摘 | Xiaobin Wang Xianhui Qin Hakan Demirtas Jianping Li Guangyun Mao Yong Huo Ningling Sun Lisheng Liu Xiping Xu | 2007 | 2007 (9576)2007，，9576： | 1 |
| 3 | Efficacy of folic acid supplementation in stroke prevention: a meta-analysis显示文摘 | Xiaobin Wang Xianhui Qin Hakan Demirtas Jianping Li Guangyun Mao Yong Huo Ningling Sun Lisheng Liu Xiping Xu | 2007 | The Lancet2007，，9576： | 1 |
| 4 | Efficacy of folic acid supplementation in stroke prevention: a meta-analysis显示文摘 | Xiaobin Wang Xianhui Qin Hakan Demirtas Jianping Li Guangyun Mao Yong Huo Ningling Sun Lisheng Liu Xiping Xu | 2007 | The Lancet2007，，9576： | 1 |
| 5 | Bioinspired mechanically interlocking holey graphene@SiO_(2)anode显示文摘Mechanically interlocking structures that can enhance adhesion at the interface and regulate the stress distribution have been widely observed in biological systems.Inspired by the biological structures in the wings of beetles,we synthesized a holey graphene@SiO_(2)anode with strong mechanical interlocking,characterized it electrochemically,and explained its performance by finite element analysis and density functional calculations.The mechanically interlocking structure enhances lithium-ion(Li^(+))storage by transmitting the strain from SiO_(2)to the holey graphene and by a mechano-electrochemical coupling effect.The interlocking fit hinders the abscission of SiO_(2)and the distinctive structure reduces the stress and strain of SiO_(2)during(de)lithiation.The positive mechano-electrochemical coupling effect preserves the amount of electrochemically active phase(LixSi)during cycles and facilitates Li+diffusion.Therefore,the capacity shows only a slight attenuation after 8000 cycles(cycling stability),and the specific capacity is~1200 mA h g^(−1)at 5 A/g(rate-performance).This study furnishes a novel way to design high-performance Li^(+)/Na+/K^(+)/Al3^(+)anodes with large volume expansion. | Fei Wang Xiaobin Liao Haoyu Wang Yan Zhao Jian Mao Donald G.Truhlar | 2022 | Interdisciplinary Materials2022，1，4： | 1 |
| 6 | Efficacy of folic acid supplementation in stroke prevention: a meta-analysis显示文摘 | Xiaobin Wang Xianhui Qin Hakan Demirtas Jianping Li Guangyun Mao Yong Huo Ningling Sun Lisheng Liu Xiping Xu | 2007 | The Lancet . 2007 (9576)2007，，9576： | 1 |
| 7 | Optimization of carbon source and carbon/nitrogen ratio for cordycepin production by submerged cultivation of medicinal mushroom Cordyceps militaris 显示文摘 | Mao Xiaobin Eksriwong T Chauvatcharin S | 2005 | Process Biochemistry2005，40，5： | 1 |
| 8 | A framework of force of information influence and application for C4KISR system显示文摘The subversive nature of information war lies not only in the information itself, but also in the circulation and application of information. It has always been a challenge to quantitatively analyze the function and effect of information flow through command, control, communications, computer, kill, intelligence,surveillance, reconnaissance (C4KISR) system. In this work, we propose a framework of force of information influence and the methods for calculating the force of information influence between C4KISR nodes of sensing, intelligence processing,decision making and fire attack. Specifically, the basic concept of force of information influence between nodes in C4KISR system is formally proposed and its mathematical definition is provided. Then, based on the information entropy theory, the model of force of information influence between C4KISR system nodes is constructed. Finally, the simulation experiments have been performed under an air defense and attack scenario. The experimental results show that, with the proposed force of information influence framework, we can effectively evaluate the contribution of information circulation through different C4KISR system nodes to the corresponding tasks. Our framework of force of information influence can also serve as an effective tool for the design and dynamic reconfiguration of C4KISR system architecture. | MAO Shaojie DIAO Lianwang SUN Yu WANG Heng YI Kan XU Xin MAO Xiaobin ZHANG Kecheng SHENG Long | 2024 | Journal of Systems Engineering and Electronics2024，35，2： | 0 |
| 9 | Application Prospect of 3D Printing Technology in Refractory Precast Components显示文摘3D printing is a rapid prototyping technology to shape materials or objects through printing layer by layer driven by digital models, which can be adopted for the manufacture of refractory precast components. Thus, the production technology of refractory precast components as well as the technique and advantages of 3D printing was introduced. The feasibility and application prospect of 3D printing concrete, contour crafting and adhesive 3D printing in refractory precast components were presented. | MAO Limin HU Chenxi YANG Haiyun LIU Jiwang HE Zehong QING Xiaobin CAI Zhongkai | 2019 | China's Refractories2019，28，2： | 0 |
| 10 | WC/Co_(7)Fe_(3)heterojunction embedded in N,P co-doped hierarchical carbon enables rechargeable/flexible Zn-air battery显示文摘Rational design and synthesis of bifunctional oxygen electrocatalysts with high activity and stability are key challenges in the development of rechargeable Zn-air batteries(ZABs).In this paper,tungsten carbide(WC)and Co_(7)Fe_(3)embedded in N,P co-doped hierarchical carbon(WC/Co_(7)Fe_(3)-NPHC)was prepared by using zeolite imidazolate frameworks as precursor.Density functional theory demonstrates that the mutual adjustment among the WC,Co_(7)Fe_(3),and N,P co-doped carbon at the three-phase heterojunction interface makes the catalyst possess moderate adsorption strength,and greatly improves the conductivity and electron transfer rate of the catalyst.As a result,the WC/Co_(7)Fe_(3)-NPHC exhibits a low overall oxygen redox potential difference of 0.72 V,while the ZAB assembled by WC/Co_(7)Fe_(3)-NPHC as an air cathode exhibits ultra-long cycle stability of over 550 h.Futhermore,WC/Co_(7)Fe_(3)-NPHC can keep good charge and discharge stability at different bending angles when applied to flexible solid ZAB. | Huimin Mao Xiaobin Liu Siqi Wu Yixin Fu Guishan Liu Guizhong Zhou Lei Wang | 2023 | Nano Research2023，16，2： | 0 |
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