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| 1 | 冠状动脉内影像学临床应用专家共识(第一部分):对冠状动脉介入治疗的指导与优化显示文摘欧洲心血管介入协会(EAPCI)专家组系统总结了血管内超声(IVUS)和光学相干断层成像(OCT)这两种血管内影像学检查临床应用指征的现有证据,提供了关于IVUS和OCT指导经皮冠状动脉介入治疗(PCI)的应用价值,并明确了最可能从腔内影像学指导的介入治疗中获得临床收益的患者或病变类型,同时详细论述了PCI前如何使用IVUS或OCT优化支架尺寸(支架长度和直径)和手术策略的选择。此外,专家推荐对支架失败(支架内再狭窄或支架内血栓形成)的患者应常规进行冠状动脉内影像学检查,并首选OCT。最后,重点论述了IVUS和OCT在指导PCI和评估支架失败两个方面的优势和局限性,并对未来需要深入研究的领域进行了展望。 | Lorenz Raber Gary S Mintz Konstantinos C Koskinas Thomas W Johnson Niels R Holm Yoshinubo Onuma Maria D Radu Michael Joner Bo Yu Haibo Jia Nicolas Meneveau Jose M.de la Torre Hemandez Javier Escaned Jonathan Hill Francesco Prati Antonio Colombo Carlo di Mario Evelyn Regar Davide Capodanno William Wijns Robert A Byme Giulio Guagliumi | 2019 | 中华心血管病杂志2019，47，1： | 17 |
| 2 | Comparison of detection and quantification of HBV DNA in chronic HBeAg negative and positive patients by Abbott RealTime HBV and Roche Cobas TaqMan HBV assays显示文摘 | Carol J. Morris Mary Hill Maria de Medina Christine Herman Gavin A. Cloherty Paul Martin | 2013 | Journal of Virological Methods2013，，： | 2 |
| 3 | Class-1 hemoglobin and antioxidant metabolism in alfalfa roots显示文摘 | Abir U. Igamberdiev Maria Stoimenova Csaba Seregélyes Robert D. Hill | 2006 | Planta2006，，5： | 1 |
| 4 | Mutations in a novel gene lead to kidney tumors, lung wall defects, and benign tumors of the hair follicle in patients with the Birt-Hogg-Dubé syndrome显示文摘 | Michael L. Nickerson Michelle B. Warren Jorge R. Toro Vera Matrosova Gladys Glenn Maria L. Turner Paul Duray Maria Merino Peter Choyke Christian P. Pavlovich Nirmala Sharma McClellan Walther David Munroe Rob Hill Eamonn Maher Cheryl Greenberg Michael I. L | 2002 | Cancer Cell2002，，2： | 1 |
| 5 | Mutations in a novel gene lead to kidney tumors, lung wall defects, and benign tumors of the hair follicle in patients with the Birt-Hogg-Dubé syndrome显示文摘 | Michael L. Nickerson Michelle B. Warren Jorge R. Toro Vera Matrosova Gladys Glenn Maria L. Turner Paul Duray Maria Merino Peter Choyke Christian P. Pavlovich Nirmala Sharma McClellan Walther David Munroe Rob Hill Eamonn Maher Cheryl Greenberg Michael I. L | 2002 | Cancer Cell2002，，2： | 1 |
| 6 | Compari- son of detection and quantification of HBV DNA in chronic HBeAg negative and positive patients by Ab- bott RealTime HBV and Roche Cobas TaqMan HBV assays显示文摘 | Carol J Morris Mary Hill Maria | 2013 | Journal of Virological Methods2013，193，2： | 1 |
| 7 | Expression and splicing of the insulin -like growth factor gene in rodent muscle is associated with muscle satellite (stem) cell activation following local tissue damage 显示文摘 | MARIA HILL GEOFFREY GOLDSPINK | 2003 | Physiol2003，549，2： | 1 |
| 8 | Muscle satellite (stem) cell activation during local tissue injury and repair 显示文摘 | MARIA HILL WERNIG A GOLDSPINK G | 2003 | Anat2003，203，： | 1 |
| 9 | Comparison of detection and quantification of HBV DNA in chronic HBeAg negative and positive patients by Abbott RealTime HBV and Roche Cobas TaqMan HBV assays显示文摘 | Carol J. Morris Mary Hill Maria de Medina Christine Herman Gavin A. Cloherty Paul Martin | 2013 | Journal of Virological Methods2013，，： | 1 |
| 10 | Does it matter where you work? A comparison of how three work venues (traditional office,virtual office,and home office) influence aspects of work and personal/family life显示文摘 | E Jeffrey Hill Maria Ferris Vjollca | 2003 | Journal of Vocational Behavior2003，63，22： | 1 |
| 11 | Mutations in a novel gene lead to kidney tumors, lung wall defects, and benign tumors of the hair follicle in patients with the Birt-Hogg-Dubé syndrome显示文摘 | Michael L. Nickerson Michelle B. Warren Jorge R. Toro Vera Matrosova Gladys Glenn Maria L. Turner Paul Duray Maria Merino Peter Choyke Christian P. Pavlovich Nirmala Sharma McClellan Walther David Munroe Rob Hill Eamonn Maher Cheryl Greenberg Michael I. L | 2002 | Cancer Cell2002，，2： | 1 |
| 12 | A Cross-cultural Test of the Work-Family Interface in 48 Countries显示文摘 | E Jeffrey Hill Chongming Yang Alan J Hawkins Maria Ferris | | 0，，： | 1 |
| 13 | Genomic organization, comparative analysis, and genetic polymorphisms of the bovine and ovine prion Doppel genes (PRND)显示文摘 | Sergio Comincini Maria G. Foti Michael A. Tranulis David Hills Giovanni Di Guardo Gabriele Vaccari John L. Williams Ingrid Harbitz Luca Ferretti | 2001 | Mammalian Genome2001，，9： | 1 |
| 14 | Mutations in a novel gene lead to kidney tumors, lung wall defects, and benign tumors of the hair follicle in patients with the Birt-Hogg-Dubé syndrome显示文摘 | Michael L. Nickerson Michelle B. Warren Jorge R. Toro Vera Matrosova Gladys Glenn Maria L. Turner Paul Duray Maria Merino Peter Choyke Christian P. Pavlovich Nirmala Sharma McClellan Walther David Munroe Rob Hill Eamonn Maher Cheryl Greenberg Michael I. L | 2002 | Cancer Cell2002，，2： | 1 |
| 15 | Expression and splicing of the insulin-like growth factor gene in rodent muscle is associated with muscle satellite (stem) cell activation following local tissue damage 显示文摘 | Maria Hill Geoffrey Goldspink | 2003 | J Physiol2003，549，1： | 1 |
| 16 | The Swedish Supreme Administrative Court Totally Disregards Tax Treaty: A Critical Analysis of a CFC Judgment 显示文摘 | Maria Hilling | 2008 | Intertax2008，36，10： | 1 |
| 17 | Radiographic findings in type 3 b Gaucher disease显示文摘 | Suvimol Chirathivat Hill Bonita M. Damaska Maria Tsokos Constance Kreps Roscoe O. Brady Norman W. Barton | 1996 | Pediatric Radiology1996，，12： | 1 |
| 18 | Prevalence and underdiagnosis of chronic obstructive pulmonary disease among patients at risk in primary care显示文摘 | Hill Kylie Goldstein Roger S Guyatt Gordon H Blouin Maria Tan Wan C Davis Lori L Heels-Ansdell Diane M Erak Marko Bragaglia Pauline J Tamari Itamar E Hodder Richard Stanbrook Matthew B | 2010 | Canadian Medical Association. Journal2010，，7： | 1 |
| 19 | Genomics-driven derivatization of the bioactive fungal sesterterpenoid variecolin:Creation of an unnatural analogue with improved anticancer properties显示文摘A biosynthetic gene cluster for the bioactive fungal sesterterpenoids variecolin(1)and variecolactone(2)was identified in Aspergillus aculeatus ATCC 16872.Heterologous production of 1 and 2 was achieved in Aspergillus oryzae by expressing the sesterterpene synthase VrcA and the cytochrome P450 VrcB.Intriguingly,the replacement of VrcB with homologous P450s from other fungal terpenoid pathways yielded three new variecolin analogues(5-7).Analysis of the compounds’anticancer activity in vitro and in vivo revealed that although 5 and 1 had comparable activities,5 was associated with significantly reduced toxic side effects in cancer-bearing mice,indicating its potentially broader therapeutic window.Our study describes the first tests of variecolin and its analogues in animals and demonstrates the utility of synthetic biology for creating molecules with improved biological activities. | Dexiu Yan Jemma Arakelyan Teng Wan Ritvik Raina Tsz Ki Chan Dohyun Ahn Vladimir Kushnarev Tsz Kiu Cheung Ho Ching Chan Inseo Choi Pui Yi Ho Feijun Hu Yujeong Kim Hill Lam Lau Ying Lo Law Chi Seng Leung Chun Yin Tong Kai Kap Wong Wing Lam Yim Nikolay S.Karnaukhov Richard Y.C.Kong Maria V.Babak Yudai Matsuda | 2024 | Acta Pharmaceutica Sinica B2024，14，1： | 0 |
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