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| 1 | 炎症和老化在年龄相关性黄斑变性和葡萄膜黑色素瘤中的作用显示文摘许多眼科疾病在中老年人群中的患病率高于其他年龄组,随着全球老龄化社会的到来,眼科医师面临着年龄相关性眼病疾病谱迅速扩大的挑战,加强年龄相关性眼病的预防对于中老年人的健康有着重要意义。因此,了解年龄相关性黄斑变性(AMD)、青光眼和葡萄膜黑色素瘤易在老年人中发病的原因至关重要。我们先前的动物实验研究表明,正常的老化过程伴随着炎症反应,这种反应增加了眼部疾病发病的风险,而加重炎症反应的环境因素是吸烟。目前已发现炎症参与AMD的发病和进展,并且可能在青光眼、葡萄膜黑色素瘤的病理过程中发挥作用,巨噬细胞和淋巴细胞增加了肿瘤转移的风险。一些实验研究也表明,巨噬细胞在脉络膜/视网膜炎症、眼内肿瘤等疾病中发挥关键作用。巨噬细胞分为M1型和M2型,前者刺激特异性免疫反应,后者可刺激血管的生成。在机体老化过程中,M1型的功能可以向M2型转化,从而可能促进AMD和肿瘤的进展。深入研究巨噬细胞的特性有助于老化过程的干预和年龄相关性眼病的预防。 | Martine J. Jager L. Ho L. V. Ly | 2013 | 中华实验眼科杂志2013，31，1： | 5 |
| 2 | Risk factors for post-ERCP pancreatitis: A prospective, multicenter study显示文摘 | Martin L. Freeman James A. DiSario Douglas B. Nelson M.Brian Fennerty John G. Lee David J. Bjorkman Carol S. Overby Johannes Aas Michael E. Ryan Gary S. Bochna Michael J. Shaw Harry W. Snady Robert V. Erickson Joseph P. Moore Joseph P. Roel | 2001 | Gastrointestinal Endoscopy2001，，4： | 5 |
| 3 | Slotting Allowances and New Product Introductions显示文摘 | Martin A. Lariviere V. Padmanabhan | 1997 | Marketing Science1997，，2： | 3 |
| 4 | Quality Improvement Guidelines for the Treatment of Lower Extremity Deep Vein Thrombosis with Use of Endovascular Thrombus Removal显示文摘 | Suresh Vedantham Patricia E. Thorpe John F. Cardella Clement J. Grassi Nilesh H. Patel Hector Ferral Lawrence V. Hofmann Bertrand M. Janne d’Othée Vittorio P. Antonaci Elias N. Brountzos Daniel B. Brown Louis G. Martin Alan H. Matsumoto Steven G. Meranze | 2006 | Journal of Vascular and Interventional Radiology2006，，3： | 3 |
| 5 | The Common Feature of Leukemia-Associated IDH1 and IDH2 Mutations Is a Neomorphic Enzyme Activity Converting α-Ketoglutarate to 2-Hydroxyglutarate显示文摘 | Patrick S. Ward Jay Patel David R. Wise Omar Abdel-Wahab Bryson D. Bennett Hilary A. Coller Justin R. Cross Valeria R. Fantin Cyrus V. Hedvat Alexander E. Perl Joshua D. Rabinowitz Martin Carroll Shinsan M. Su Kim A. Sharp Ross L. Levine Craig B. Thompson | 2010 | Cancer Cell2010，，3： | 2 |
| 6 | Survival and symptom progression in a geographically based cohort of patients with primary biliary cirrhosis: Follow-up for up to 28 years显示文摘 | Martin Prince Amanda Chetwynd Wendy Newman Jane V. Metcalf Oliver F.W. James | 2002 | Gastroenterology2002，，4： | 2 |
| 7 | Magnesium as a biodegradable and bioabsorbable material for medical implants显示文摘 | Harpreet S. Brar Manu O. Platt Malisa Sarntinoranont Peter I. Martin Michele V. Manuel | 2009 | JOM2009，，9： | 2 |
| 8 | Variation of soil respiration at three spatial scales: Components within measurements, intra-site variation and patterns on the landscape显示文摘 | Jonathan G. Martin Paul V. Bolstad | 2009 | Soil Biology and Biochemistry2009，，3： | 2 |
| 9 | Trans-catheter arterial chemoembolization as first-line treatment for hepatic metastases from endocrine tumors显示文摘 | Alain Roche Baragur V. Girish Thierry de Baère Eric Baudin Valérie Boige Dominique Elias Philippe Lasser Martin Schlumberger Michel Ducreux | 2003 | European Radiology2003，，1： | 2 |
| 10 | Laboratory infection with Zika virus after vaccination against yellow fever显示文摘 | A. R. Filipe C. M. V. Martins Helena Rocha | 1973 | Archiv für die gesamte Virusforschung1973，，： | 2 |
| 11 | 16 S rRNA survey revealed complex bacterial communities and evidence of bacterial interference on human adenoids显示文摘 | Tiantian Ren Dominique Ulrike Glatt Tam Nhu Nguyen Emma Kaitlynn Allen Stephen V. Early Michele Sale Birgit Winther Martin Wu | 2012 | Environ Microbiol2012，，2： | 2 |
| 12 | Intermittent Androgen Deprivation for Locally Advanced and Metastatic Prostate Cancer: Results from a Randomised Phase 3 Study of the South European Uroncological Group显示文摘 | Fernando E.C. Calais da Silva Aldo V. Bono Peter Whelan Maurizio Brausi Anton Marques Queimadelos Jose A. Portillo Martin Ziya Kirkali Fernando M.V. Calais da Silva Chris Robertson | 2009 | European Urology2009，，6： | 2 |
| 13 | National Institute of Neurological Disorders and Stroke–Canadian Stroke Network Vascular Cognitive Impairment Harmonization Standards显示文摘 | Vladimir Hachinski Costantino Iadecola Ron C. Petersen Monique M. Breteler David L. Nyenhuis Sandra E. Black William J. Powers Charles DeCarli Jose G. Merino Raj N. Kalaria Harry V. Vinters David M. Holtzman Gary A. Rosenberg Anders Wallin Martin Dichgans | 2006 | Stroke2006，，9： | 2 |
| 14 | Modelling brittle failure of rock显示文摘 | V. Hajiabdolmajid P.K. Kaiser C.D. Martin | 2002 | International Journal of Rock Mechanics and Mining Sciences2002，，6： | 2 |
| 15 | Synthesis Gas Production from Natural Gas on Supported Pt Catalysts显示文摘,联合部分氧化并且有 CO2 或蒸气的甲烷改过甲烷的汽车热的改过,与 Pt/Al2O3 Pt/ZrO2 和 Pt/CeO2 催化剂被执行,在 300 ¨ C 的一个温度范围 900 ??6 号元素碳的化学符号。也就是,汽车热的改过发生在二个同时的阶段甲烷的全部的燃烧并且与蒸气和 CO2 无变化的甲烷改过,与百分之百从 450 开始的 O2 变换 ??6 号元素碳的化学符号。为有 CO2 改过的联合, Pt/CeO2catalyst 在 800 点显示出最低起始的活动 ??6 号元素碳的化学符号,和在 40 h 在溪流上上的最高的稳定性。这催化剂也在 800 点与蒸气为反应介绍了最好的表演 ??6 号元素碳的化学符号。到在铈土上支持的催化剂的焦形成的更高的抵抗由于金属支持相互作用和在氧化物格子的氧的更高的活动性。给词调音:甲烷;冒热气改过;CO2 改过;部分氧化;汽车热的改过;铂催化剂;铈土; | Mariana M. V. M. Souza Octávio R. Macedo Neto Martin Schmal | 2006 | Journal of Natural Gas Chemistry2006，15，1： | 2 |
| 16 | Risk factors for post-ERCP pancreatitis: A prospective, multicenter study显示文摘 | Martin L. Freeman James A. DiSario Douglas B. Nelson M.Brian Fennerty John G. Lee David J. Bjorkman Carol S. Overby Johannes Aas Michael E. Ryan Gary S. Bochna Michael J. Shaw Harry W. Snady Robert V. Erickson Joseph P. Moore Joseph P. Roel | 2001 | Gastrointestinal Endoscopy2001，，4： | 2 |
| 17 | Functional and Anatomical Diagnosis of Coronary Artery Stenoses显示文摘 | Abhijit Sinha Roy Martin R. Back Saeb F. Khoury Eric W. Schneeberger Lloyd H. Back Vijaya V. Velury Ronald W. Millard Rupak K. Banerjee | 2008 | Journal of Surgical Research2008，，： | 2 |
| 18 | Preservation and Incorporation of Valuable Endoscopic Innovations (PIVI) on the use of endoscopy simulators for training and assessing skill显示文摘 | Jonathan Cohen Brian P. Bosworth Amitabh Chak Brian J. Dunkin Dayna S. Early Lauren B. Gerson Robert H. Hawes Adam V. Haycock Juergen H. Hochberger Joo Ha Hwang John A. Martin Peter R. McNally Robert E. Sedlack Melina C. Vassiliou | 2012 | Gastrointestinal Endoscopy2012，，3： | 1 |
| 19 | Bilirubin: A Natural Inhibitor of Vascular Smooth Muscle Cell Proliferation显示文摘 | Robert ?llinger Martin Bilban Anna Erat Alberto Froio James McDaid Shivraj Tyagi Eva Csizmadia Aurelio V. Gra?a-Souza Angela Liloia Miguel P. Soares Leo E. Otterbein Anny Usheva Kenichiro Yamashita Fritz H. Bach | 2005 | Circulation2005，，7： | 1 |
| 20 | Short Hairpin RNA Screen Reveals Bromodomain Proteins as Novel Targets in Acute Myeloid Leukemia显示文摘 | Gerd A. Blobel Anna Kalota Patricia V. Sanchez Martin Carroll | 2011 | Cancer Cell2011，，3： | 1 |
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