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| 1 | Analysis of status and countermeasures of cancer incidence and mortality in China显示文摘Cancer is the leading cause of human deaths in the world and produces serious economic burdens. On September 12, 2018, the academic journal A Cancer Journal for Clinicians published an article about the latest statistics of cancers worldwide, which provided a status report on the global burden of 36 cancers in 185 countries worldwide. Cancer has also become a serious public health problem in China and caused more and more attention of the government and people in recent years. This review analyzes the incidence, mortality and prevalent trend of cancers in China, discusses the reasons behind this status, and reviews the potential countermeasures for cancer prevention and control in China. | Chunchun Wu Mengna Li Hanbing Meng Yukun Liu Weihong Niu Yao Zhou Ran Zhao Yumei Duan Zhaoyang Zeng Xiaoling Li Guiyuan Li Wei Xiong Ming Zhou | 2019 | Science China(Life Sciences)2019，62，5： | 175 |
| 2 | LncRNA-HOTAIR inhibition aggravates oxidative stress-induced H9c2 cells injury through suppression of MMP2 by miR-125显示文摘 | Linlin Li Mengna Zhang Weizhen Chen Ruirui Wang Zi Ye Yanyan Wang Xiao Li Cheguo Cai | 2018 | Acta Biochimica et Biophysica Sinica2018，50，10： | 20 |
| 3 | bHLH121 Functions as a Direct Link that Facilitates the Activation of FIT by bHLH IVc Transcription Factors for Maintaining Fe Homeostasis in Arabidopsis显示文摘Iron(Fe)deficiency is prevalent in plants grown in neutral or alkaline soil.Plants have evolved sophisticated mechanisms that regulate Fe homeostasis,ensuring survival.In Arabidopsis,FER-LIKE IRON DEFICIENCY-INDUCED TRANSCRIPTION FACTOR(FIT)is a crucial regulator of Fe-deficiency response.FIT is activated indirectly by basic helix-loop-helix(bHLH)IVc transcription factors(TFs)under Fed eficiency;how ever,it remains unclear which protein(s)act as the linker to mediate the activation of FIT by bHLH IVc TFs.In this study,we characterize the functions of bHLH121 and demonstrate that it directly associates with the FIT promoter.We found that loss-of-function mutations of bHLH121 cause severe Fedeficiency symptoms,reduced Feaccum ulation,and disrupted expression of genes associated with Fehomeostasis.Genetic analysis showed that FIT is epistatic to bHLH121 and FIT overexpression partially rescues the bhlh121 mutant.Further investigations revealed that bHLH IVc TFs interact with and promote nuclear accumulation of bHLH121.We demonstrated that bHLH121 has DNA-binding activity and can bind the prom oters of the FIT and bHLHlb genes,but we did not find that it has either direct transcriptional activation or repression activity tow ard these genes.Meanw hile,we found that bHLH121 functions downstream of and is a direct target of bHLH IVc TFs,and its expression is induced by Fe deficiency in a bHLH IV c-dependent manner.Taken together,these results establish that bHLH121 functions together with bHLH IVc TFs to positively regulate the expression of FIT and thus plays a pivotal role in maintaining Fe homeostasis in Arabidopsis. | Rihua Lei Yang Li Yuerong Cai Chenyang Li Mengna Pu Chengkai Lu Yujie Yang Gang Liang | 2020 | Molecular Plant2020，13，4： | 14 |
| 4 | Ovarian tumor-associated microRNA-20a decreases natural killer cell cytotoxicity by downregulating MICA/B expression显示文摘MicroRNAs (miRNAs ) 是小非编码的规章的 RNA 的一个班,并且在 miRNAs 的变化涉及肿瘤起源和前进。研究证明了 miR-20a 是在人的卵巢的癌症纸巾的 overexpressed 并且这 miRNA 提高长期的细胞的增长和侵略能力。在这研究,在浆液 miR-20a 表示和卵巢的癌症舞台之间的积极关联被观察。我们发现 miR-20a 直接绑,导致它的降级并且减少它 MICA/B mRNA 的 -untranslated 区域在血浆膜上铺平的蛋白质 3 ′。膜界限 MICA/B 蛋白质的减小,是 2 成员 D (NKG2D ) 受体在生来的杀手(NK ) 上发现了房间的生来的迷人的组的 ligands, γ δ + T 房间和 CD8 + T 房间,允许肿瘤房间躲避调停免疫者的杀死。尤其是,反对 miR-20a 行动提高了在 vitro 并且在肿瘤的 vivo 模型的在两个的肿瘤房间的调停 NKG2D 的杀死。一起拿,我们的数据显示在肿瘤房间的 miR-20a 的增加的层次可以间接地由 downregulating MICA/B 压制 NK 房间 cytotoxicity 表达式。这些数据提供在转移能力和 NK 房间的肿瘤房间的有免疫力的逃跑之间的一个潜在的连接。 | Jingyan Xie Mengna Liu Yujuan Li Yunzhong Nie Qiongyu Mi Shuli Zhao | 2014 | Cellular & Molecular Immunology2014，11，5： | 10 |
| 5 | Review of energy consumption research for papermaking industry based on life cycle analysis显示文摘Papermaking industry is a high-energy-consuming industry with long supply chain.The growth of paper product demand further intensifies the need of energy consumption.Energy saving through the full supply chain has become a focal point for long-term sustainable development of the papermaking industry.This paper reviews the advances in life cycle analysis for the papermaking industry in recent years.All the stages from the full supply chain are involved to give a panoramic overview of the papermaking industry.The object of this paper is to provide scientific basis to industry and decision-makers with profound understanding of the energy consumption and energy saving potential in a life cycle perspective. | Yi Man Yulin Han Jigeng Li Mengna Hong | 2019 | Chinese Journal of Chemical Engineering2019，27，7： | 6 |
| 6 | Effects of hypoxia on survival,behavior,and metabolism of Zhikong scallop Chlamys farreri Jones et Preston 1904显示文摘Hypoxia,a frequent occurring threat in coastal regions,often results in mass mortalities of marine organisms and brings a serious ecological problem.The commercially important Zhikong scallop Chlamys farreri is being under such a threat as the risks of eutrophication and hypoxia have risen in their culture areas.However,little information has been known concerning their tolerance to hypoxia and their strategy for survival.In the present study,a 20-day experiment was conducted to determine the ef fects of hypoxia on the survival,behavior,and metabolism of Zhikong scallop.With the LC_(50)for dissolved oxygen(DO)being estimated as 1.8 mg/L,the survival of Zhikong scallop can be greatly challenged even under the moderate hypoxic condition of around 2.0 mg/L DO.The survival rate ranged from 69%to 59%when DO dropped from 3.0 to 2.0 mg/L,and it was further reduced to 47%at 1.5 mg/L DO.In hypoxic conditions,the scallops became significantly active,which may be explained as escape attempts to avoid hypoxic water.To save energy,Zhikong scallop would depress their respiration.However,when DO dropped from 3.0 to 2.0 mg/L,the oxygen consumption rate hardly changed.The upregulation of lactate dehydrogenase activity and the unrepressed phosphofructokinase activity,which often result in the unbalanced cellular homeostasis and energy budget,may account for the observed increase in the mortality rate of Zhikong scallops.In general,Zhikong scallop is sensitive to hypoxia events,though possible escape attempts,depressed respiration,and oxaloacetate-pathway may increase their survival chance. | LI Qiao ZHANG Fang WANG Minxiao LI Mengna SUN Song | 2020 | Journal of Oceanology and Limnology2020，38，2： | 5 |
| 7 | Oryza sativa FER-LIKE FE DEFICIENCY-INDUCED TRANSCRIPTION FACTOR(OsFIT/OsbHLH156)interacts with OsIRO2 to regulate iron homeostasis显示文摘Iron(Fe)is indispensable for the growth and development of plants.It is well known that FER-LIKE FE DEFICIENCY-INDUCED TRANSCRIPTION FACTOR(FIT)is a key regulator of Fe uptake in Arabidopsis.Here,we identify the Oryza sativa FIT(also known as Osb HLH156)as the interacting partner of IRON-RELATED BHLH TRANSCRIPTION FACTOR 2(OsIRO2)that is critical for regulating Fe uptake.The OsIRO2 protein is localized in the cytoplasm and nucleus,but OsFIT facilitates the accumulation of OsIRO2 in the nucleus.Loss-of-function mutations of OsFIT result in decreased Fe accumulation,severe Fe-deficiency symptoms,and disrupted expression of Feuptake genes.In contrast,OsFIT overexpression promotes Fe accumulation and the expression of Fe-uptake genes.Genetic analyses indicate that OsFIT and OsIRO2 function in the same genetic node.Further analyses suggest that OsFIT and OsIRO2 form a functional transcription activation complex to initiate the expression of Fe-uptake genes.Our findings provide a mechanism understanding of how rice maintains Fe homeostasis. | Gang Liang Huimin Zhang Yang Li Mengna Pu Yujie Yang Chenyang Li Chengkai Lu Peng Xu Diqiu Yu | 2020 | Journal of Integrative Plant Biology2020，62，5： | 4 |
| 8 | Frequency steering of spaceborne clocks based on XPNAV-1 observations显示文摘Due to high stable rotations, timing of pulsars provides a natural tool to correct the frequency deviation of spaceborne atomic clocks. Based on processing the observational data about a year of Crab pulsar given by XPNAV-1 satellite, we study the possibility of correcting the frequency deviation of spaceborne atomic clocks using pulsar timing. According to the observational data in X-ray band and the timing model parameters from radio observations, the pre-fit timing residuals with a level of 67.66 μs are obtained. By fitting the slope of the timing residuals affected by the faked frequency-biased reference clock, we estimated successfully the relative frequency deviation of the reference clock. For a satellite clock with frequency deviation of the order about 10^(-12), a calibration accuracy with relative error of about 2% can be obtained from the Crab pulsar’s data for one year.The stability of the time scale based on Crab pulsar is about 10^(-12) for an interval of one year. | Mengna HAN Minglei TONG Liansheng LI Yongqiang SHI Tinggao YANG Yuping GAO | 2023 | Chinese Journal of Aeronautics2023，36，6： | 3 |
| 9 | Landing site topographic mapping and rover localization for Chang’e-4 mission显示文摘This paper presents the techniques and results of landing-site topographic mapping and rover localization using orbital,descent and rover images in the Chang’e-4 mission.High-resolution maps of the landing site are generated from orbital and descent images.Local digital elevation models and digital orthophoto maps with 0.02 m resolution are generated at each waypoint.The location of the lander is determined as(177.588?E,45.457?S)using festure-matching techniques.The cross-site visual localization method is routinely used to localize the rover at each waypoint to reduce error accumulation from wheel slippage and IMU drift in dead reckoning.After the first five lunar days,the rover travels 186.66 m from the lander,according to the cross-site visual localization.The developed methods and results have been directly utilized to support the mission’s operations.The maps and localization information are also valuable for supporting multiple scientific explorations of the landing site. | Zhaoqin LIU Kaichang DI Jian LI Jianfeng XIE Xiaofeng CUI Luhua XI Wenhui WAN Man PENG Bin LIU Yexin WANG Sheng GOU Zongyu YUE Tianyi YU Lichun LI Jia WANG Chuankai LIU Xin XIN Mengna JIA Zheng BO Jia LIU Runzhi WANG Shengli NIU Kuan ZHANG Yi YOU Bing LIU Jiangang LIU | 2020 | Science China(Information Sciences)2020，63，4： | 3 |
| 10 | A novel gatifloxacin-loaded intraocular lens for prophylaxis of postoperative endophthalmitis显示文摘Postoperative endophthalmitis(POE)has been the most threatening complication after cataract surgery,which perhaps can be solved by the antibiotic-loaded intraocular lens(IOL).However,most drug-loaded IOLs demonstrate insufficient drug quantity,short release time,increased implantation-related difficulties or other noticeable drawbacks.To prevent POE and to address these deficiencies,a drug-loaded copolymer IOL,prepared from poly(urethane acrylate)prepolymer,isobornyl methacrylate(IBOMA),N-vinyl-2-pyrrolidone(NVP),Irgacure 819,RUVA-93,and gatifloxacin(GAT),was rapidly fabricated via photocuring and by using a 3D-printed mold.This composite displayed an outstanding and controllable GAT release behavior in vitro,a high light transmittance,and a moderate refractive index.Also,it demonstrated improved strain stress and elongation compared with the reference commercial acrylic IOL material.In vivo tests demonstrated satisfying released drug concentration at the early treatment stage.In vitro and in vivo studies further confirmed the remarkable bacterial inhibition and prevention of POE by the proposed IOL,which also displayed good biocompatibility.These findings suggested that the GAT-loaded IOL could be a promising implant to prevent and cure POE,also the proposed methods could inspire more designs for various medical applications. | Mengna Li Jing-Wei Xu Jiayong Li Wei Wang Chenqi Luo Haijie Han Zhi-Kang Xu Ke Yao | 2023 | Bioactive Materials2023，，2： | 2 |
| 11 | One-pot synthesis of Au@Pt star-like nanocrystals and their enhanced electrocatalytic performance for formic acid and ethanol oxidation显示文摘 | Yi Peng Lidong Li Ran Tao Lingyu Tan Mengna Qiu Lin Guo | 2018 | Nano Research2018，11，6： | 2 |
| 12 | A Method for Alpine Wetland Delineation and Features of Border: Zoigê Plateau, China显示文摘Accurate wetland delineation is the basis of wetland definition and mapping, and is of great importance for wetland management and research. The Zoigê Plateau on the Qinghai-Tibet Plateau was used as a research site for research on alpine wetland delineation. Several studies have analyzed the spatiotemporal pattern and dynamics of these alpine wetlands, but none have addressed the issues of wetland boundaries. The objective of this work was to discriminate the upper boundaries of alpine wetlands by coupling ecological methods and satellite observations. The combination of Landsat 8 images and supervised classification was an effective method for rapid identification of alpine wetlands in the Zoigê Plateau. Wet meadow was relatively stable compared with hydric soils and wetland hydrology and could be used as a primary indicator for discriminating the upper boundaries of alpine wetlands. A slope of less than 4.5° could be used as the threshold value for wetland delineation. The normalized difference vegetation index(NDVI) in 434 field sites showed that a threshold value of 0.3 could distinguish grasslands from emergent marsh and wet meadow in September. The median normalized difference water index(NDWI) of emergent marsh remained more stable than that of wet meadow and grasslands during the period from September until July of the following year. The index of mean density in wet meadow zones was higher than the emergent and upland zones. Over twice the number of species occurred in the wet meadow zone compared with the emergent zone, and close to the value of upland zone. Alpine wetlands in the three reserves in 2014 covered 1175.19 km2 with a classification accuracy of 75.6%. The combination of ecological methods and remote sensing technology will play an important role in wetland delineation at medium and small scales. The correct differentiation between wet meadow and grasslands is the key to improving the accuracy of future wetland delineation. | ZHENG Yaomin NIU Zhenguo GONG Peng LI Mengna HU Lile WANG Lei YANG Yuxiang GU Hai-jun MU Jinrong DOU Gejia XUE Hui WANG Lin LI Hua DOU Gejie DANG Zhicairang | 2017 | Chinese Geographical Science2017，27，5： | 2 |
| 13 | PVT1 affects ENIT and cell proliferation and migration via regulating p21 in triple-negative breast cancer cells cultured with mature adipogenic medium显示文摘Excessive adiposity has long been proved to be associated with greater incidence and mortality of breast cancer in post-menopausal women.However,the effects and underlying mechanisms of human adipocytes on breast cancer cells remain largely unknown.In recent years,several reports have revealed the oncogenic role of long non-coding RNA PVT1 in breast cancer.Here,we aimed to investigate the role and underlying mechanisms of PVT1 in triple-negative breast cancer (TNBC)cells cultured with mature adipogenic medium.At first,we successfully induced adipogenic differentiation from human adipose-derived mesenchymal stern cells and collected the mature adipogenic medium to mimic excessive adiposity.Our results demonstrated that the mature adipogenic medium promoted the epithelial-mesenchymal transition,enhanced the cell viability and migration potential of TNBC cells.In addition,we proved that mature adipogenic medium affected the PVT1 expression and inhibition of the PVT1 disturbed the role of mature adipogenic medium in TNBC cells.Finally,we illustrated that repression of p21 restored the phenotype caused by PVT1 knockdown in TNBC cells treated with mature adipogenic medium.Taken together,our results demonstrated that PVT1 affected the role of mature adipogenic medium in TNBC cells via modulating p21 expression. | Lingli Wang Ruirui Wang Zi Ye Yanyan Wang Xiao Li Weizhen Chen Mengna Zhang Cheguo Cai | 2018 | Acta Biochimica et Biophysica Sinica2018，50，12： | 2 |
| 14 | Dynamic simulations of the late MIS 3 transgressions in the East China Sea and southern Yellow Sea,China显示文摘Abundant evidences of higher sea levels from Jiangsu and Fujian coasts have proved a marine transgression event during 30–40 ka BP, suggesting that there was a stage with high sea level and a warm climate when ice sheets shrank in the Northern Hemisphere. The duration of 30–40 ka BP spanned a period in the late Marine Isotope Stage 3(MIS 3) and was in nature an interstadial epoch during the Last Glacial period of the Quaternary. Different from the glacial period with a cold climate, this marine transgression considered as a penultimate higher sea level during the Quaternary remains a puzzle that why the evidence is contrary to the Quaternary glacial theory. It is important to understand sea level rise for these areas sensitively responding to the global changes in the future. To recognize the key issues on sea level changes, the eustatic sea level(H_S) was defined as the glaciation-climateforced sea levels, and the relative sea level change(H_R) was defined as that a sea level record was preserved in sediment that experienced multiple secondary actions of land and sea effects. On the basis as defined above, we constructed multi-level models of climate-driven glacio-eustatic changes and land-sea systems. By integrating data sets from eight borehole cores and prescribing the boundary conditions, we simulated the changes of HS and HR in the East China Sea and southern Yellow Sea areas in the late MIS 3. The marine transgression strata from the borehole core data was identified at ca. 30 m below present sea level as a result of the collective influence of ice melting water, neotectonic subsidence, sediment compaction and terrestrial sediment filling since ca. 35 ka ago,whereas the simulated relative sea-levels turned out to be –26.3––29.9 m a.s.l. The small error involved in the simulation results of ±(2.5–4.5) m demonstrated the credibility of the results. Our results indicated that sea level change in the late MIS 3 was dominated by glacial effects, in which the eustatic sea-level was between –19.2––22.1m a.s.l. The study sheds light on the nature of sea-level changes along the east coast of China in the late MIS 3 and contributes to understanding the characteristics of marine transgression under the effects of multiple complex land-sea interactions. | YE Liangtao YU Ge LIAO Mengna LI Yongfei | 2016 | Acta Oceanologica Sinica2016，35，10： | 2 |
| 15 | Identification and characterization of endosymbiosis-related immune genes in deep-sea mussels Gigantidas platifrons显示文摘Deep-sea mussels of the subfamily Bathymodiolinae are common and numerically dominant species widely distributed in cold seeps and hydrothermal vents.During long-time evolution,deep-sea mussels have evolved to be well adapted to the local environment of cold seeps and hydrothermal vents by various ways,especially by establishing endosymbiosis with chemotrophic bacteria.However,biological processes underlying the establishment and maintenance of symbiosis between host mussels and symbionts are largely unclear.In the present study,Gigantidas platifrons genes possibly involved in the symbiosis with methane oxidation symbionts were identified and characterized by Lipopolysaccharide(LPS)pull-down and in situ hybridization.Five immune related proteins including Toll-like receptor 2(TLR2),integrin,vacuolar sorting protein(VSP),matrix metalloproteinase 1(MMP1),and leucine-rich repeat(LRR-1)were identified by LPS pull-down assay.These five proteins were all conserved in either molecular sequences or functional domains and known to be key molecules in host immune recognition,phagocytosis,and lysosome-mediated digestion.Furthermore,in situ hybridization of LRR-1,TLR2 and VSP genes was conducted to investigate their expression patterns in gill tissues of G.platifrons.Consequently,LRR-1,TLR2,and VSP genes were found expressed exclusively in the bacteriocytes of G.platifrons.Therefore,it was suggested that TLR2,integrin,VSP,MMP1,and LRR-1 might be crucial molecules in the symbiosis between G.platifrons and methane oxidation bacteria by participating in symbiosis-related immune processes. | LI Mengna CHEN Hao WANG Minxiao ZHONG Zhaoshan ZHOU Li LI Chaolun | 2020 | Journal of Oceanology and Limnology2020，38，4： | 1 |
| 16 | Temporal and spatial variations of bacterial community compositions in two estuaries of Chaohu Lake显示文摘The distinctive estuary hydrodynamics and nutrient input make the estuary ecosystem play a key role in lake ecosystems.The Nanfei River and Zhaohe River are two main inlets of Chaohu Lake,Anhui,East China.We selected estuaries of the two rivers as representative areas to study temporal and spatial changes of bacterial communities.In August(summer)and November(autumn)2016 and February(winter)and May(spring)2017,16 water and sediment samples were collected from the estuaries.Physicochemical characteristics indicate significant differences in the nutritional status and eutrophication index of the estuaries due mainly to organic input.Examination of the number of operational taxonomic units,the diversity index,the community composition,and redundancy analysis revealed the following.First,the existence of varying degrees of seasonal differences in the distribution of almost all bacteria.In addition,the species diversity in the sediment samples was higher than that in the water samples,and the dominant species differed also among these samples.Second,a large number of unknown genera were detected,especially in the sediment samples,such as unclassified Xanthomonadales incertae sedis,unclassified Anaerolineaceae,and unclassified Alcaligenaceae.Last,TP,TN,and TOC were the main influential factors that affected the bacterial community structure. | ZHANG Lei LI Li LIU Mengna HU Yao JIANG Jiahu | 2020 | Journal of Oceanology and Limnology2020，38，3： | 1 |
| 17 | Development of a target capture sequencing SNP genotyping platform for genetic analysis and genomic breeding in rapeseed显示文摘Rapeseed(Brassica napus)is an oil crop grown worldwide,making it a key plant species in molecular breeding research.However,the complexity of its polyploid genome increases sequencing costs and reduces sequencing accuracy.Target capture coupled with high-throughput sequencing is an efficient approach for detecting genetic variation at genomic regions or loci of interest.In this study,588 resequenced accessions of rapeseed were used to develop a target capture sequencing SNP genotyping platform named BnaPan50T.The platform comprised 54,765,with 54,058 resequenced markers from the pan-genome,and 855 variant trait-associated markers for 12 agronomic traits.The capture quality of BnaPan50T was demonstrated well in 12 typical accessions.Compared with a conventional genotyping array,BnaPan50T has a high SNP density and a high proportion of SNPs in unique physical positions and in annotated functional genes,promising wide application.Target capture sequencing and wholegenome resequencing in 90 doubled-haploid lines yielded 60%specificity,78%uniformity within tenfold coverage range,and 93%genotyping accuracy for the platform.BnaPan50T was used to construct a genetic map for quantitative trait loci(QTL)mapping,identify 21 unique QTL,and predict several candidate genes for yield-related traits in multiple environments.A set of 132 core SNP loci was selected from BnaPan50T to construct DNA fingerprints and germplasm identification resources.This study provides genomics resources to support target capture sequencing,genetic analysis and genomic breeding of rapeseed. | Xiaodong Li Xumei Liu Yonghai Fan Shengting Li Mengna Yu Mingchao Qian Yuling Chen Hongqiao Chen Xinchun Li Bei Liu Xinfu Xu Cunmin Qu Jiana Li Kun Lu | 2023 | The Crop Journal2023，11，2： | 1 |
| 18 | A telomere-to-telomere gap-free assembly of soybean genome显示文摘Dear Editor,Soybean(Glycine max),one of the world's most important crops,represents an indispensable source of edible oil and protein for both humans and livestock.The first soybean reference genome of the Williams 82 cultivar(Wm82)was assembled using a wholegenome shotgun approach integrated with physical and highdensity genetic maps in 2010(Schmutz et al.,2010).In addition to the first reference genome,de novo genome assemblies have been released recently for dozens of cultivated soybean accessions with the application of long-read sequencing technology(Li et al.,2014;Shen et al.,2018;Liu et al.,2020).Although those assemblies provide valuable resources for functional genomics and molecular breeding,there are still a number of unresolved gaps that impede the exploration of complex genomic regions such as centromeres and telomeres。 | Longfei Wang Mengzhu Zhang Mengna Li Xinyu Jiang Wu Jiao Qingxin Song | 2023 | Molecular Plant2023，16，11： | 1 |
| 19 | A web based tool to merge geometric morphometric data from multiple characters显示文摘Geometric morphometrics(GM) is an important method of shape analysis and increasingly used in a wide range of scientific disciplines.Presently,a single character comparison system of geometric morphometric data is used in almost all empirical studies,and this approach is sufficient for many scientific problems.However,the estimation of overall similarity among taxa or objects based on multiple characters is crucial in a variety of contexts(e.g.(semi-)automated identification,phenetic relationships,tracing of character evolution,phylogenetic reconstruction).Here we propose a new web-based tool for merging several geometric morphometrics data files from multiple characters into a single data file.Using this approach information from multiple characters can be compared in combination and an overall similarity estimate can be obtained in a convenient and geometrically rigorous manner.To illustrate our method,we provide an example analysis of 25 dung beetle species with seven Procrustes superimposed landmark data files representing the morphological variation of body features:the epipharynx,right mandible,pronotum,elytra,hindwing,and the metendosternite in dorsal and lateral view.All seven files were merged into a single one containing information on 649 landmark locations.The possible applications of such merged data files in different fields of science are discussed. | Ming Bai Jing Li Wencheng Wang Rolf G. Beutel Benjamin Wipfle Wangang Liu ShaLi Mengna Zhang Yuanyuan Lu Xingke Yang | 2017 | Zoological Systematics2017，42，1： | 1 |
| 20 | On the Development of a Model for the Prediction of Liquid Loading in Gas Wells with an Inclined Section显示文摘The ability to predict liquid loading in horizontal gas wells is of great importance for determining the time of drainage and optimizing the related production technology.In the present work,we describe the outcomes of experiments conducted using air-water mixtures in a horizontal well.The results show that the configuration with an inclined section is the most susceptible to liquid loading.Laboratory experiments in an inclined pipe were also conducted to analyze the variation of the critical gas flow rate under different angles,pressure and liquid volume(taking the equal liquid volume at inlet and outlet as the criterion for judging on the critical state).According to these results,the related angle of the inclined section ranges from 45°to 60°.Finally,a modified approach based on the Belfroid model has been used to predict the critical gas flow rate for the inclined section.After comparison with field data,this modified model shows an accuracy of 96%,indicating that it has better performances with respect to other models used in the past to predict liquid loading. | Mengna Liao Ruiquan Liao Jie Liu Shuangquan Liu Li Li Xiuwu Wang Yang Cheng | 2019 | Fluid Dynamics & Materials Processing2019，15，5： | 1 |
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