|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Mussel-inspired agarose hydrogel scaffolds for skin tissue engineering显示文摘Polysaccharide hydrogels are widely used in tissue engineering because of their superior biocompatibility and low immunogenicity.However,many of these hydrogels are unrealistic for practical applications as the cost of raw materials is high,and the fabrication steps are tedious.This study focuses on the facile fabrication and optimization of agarose-polydopamine hydrogel(APG)scaffolds for skin wound healing.The first study objective was to evaluate the effects of polydopamine(PDA)on the mechanical properties,water holding capacity and cell adhesiveness of APG.We observed that APG showed decreased rigidity and increased water content with the addition of PDA.Most importantly,decreased rigidity translated into significant increase in cell adhesiveness.Next,the slow biodegradability and high biocompatibility of APG with the highest PDA content(APG3)was confirmed.In addition,APG3 promoted full-thickness skin defect healing by accelerating collagen deposition and promoting angiogenesis.Altogether,we have developed a straightforward and efficient strategy to construct functional APG scaffold for skin tissue engineering,which has translation potentials in clinical practice. | Ting Su Mengying Zhang Qiankun Zeng Wenhao Pan Yijing Huang Yuna Qian Wei Dong Xiaoliang Qi Jianliang Shen | 2021 | Bioactive Materials2021，6，3： | 6 |
| 2 | Boron nitride microsphere/epoxy composites with enhanced thermal conductivity显示文摘As modern electronics are developed towards miniaturisation,high-degree integration and intelligentisation,a large amount of heat will be generated during the operation of devices.How to efficiently remove needless heat is becoming more and more crucial for the lifetime and performance of electronic devices.Many efforts have been made to improve the thermal conductivity of polymer composites,which is an important component of electronics.Herein,the authors report on preparation of boron nitride micosphere/epoxy composites.The cross-plane thermal conductivity of the resultant composites is up to 1.03 Wm‒1K‒1.This is attributed to the thermally conductive network formed by the peeled hexagonal boron nitride flakes.Thanks to the superior thermal stability of boron nitride micosphere,the boron nitride micosphere/epoxy composite shows a decreased coefficient of thermal expansion(53.47 ppm/K)and an increased glass transition temperature(147.2℃)compared with the pure epoxy resin.In addition,the boron nitride micosphere/epoxy composite exhibits a lower dielectric constant compared with that of the hexagonal boron nitride/epoxy composite.This strategy can potentially pave the way for the design and fabrication of materials with high cross-plane thermal conductivity and lower dielectric properties. | Jiajia Sun De Wang Yimin Yao Xiaoliang Zeng Guiran Pan Yun Huang Jiantao Hu Rong Sun Jian-Bin Xu Ching-Ping Wong | 2017 | High Voltage2017，2，3： | 2 |
| 3 | Correlation of peripheral Th17 cells and Th17-associated cytokines to the severity of carotid artery plaque and its clinical implication显示文摘 | Zhendong Liu Fanghong Lu Hui Pan Yingxin Zhao Shujian Wang Shangwen Sun Jun Li Xiaoliang Hu Lin Wang | 2011 | Atherosclerosis2011，，1： | 2 |
| 4 | Mechanism of the Effect of Bacillus coagulans on Production Performance of Laying Hens in Late Laying Period显示文摘[Objective]The paper was to investigate the mechanism of Bacillus coagulans preparation in improving production performance of laying hens in late period of laying.[Method]A total of 648 individuals of'Jingfen 1'laying hens(66 weeks of age)in late period of laying were randomly divided into four groups,six replicates each group,and each group had 27 individuals of laying hens.The laying hens in control group were fed with basal diet,and those in experimental groupsⅠ,Ⅱ and Ⅲ were fed with the basal diets added with 3.33×10^6,1×10^7,3.33×10^7 CFU/g B.coagulans,respectively.The pretrial lasted one week,and the formal test lasted eight weeks.[Result]Compared with the control group,the laying rate in group Ⅰ increased significantly,and the feed-gain ratio in experimental group Ⅱ decreased noticeably while the spleen index increased remarkably;the alkaline phosphatase activities and blood calcium content in experimental groups Ⅰ,Ⅱ and Ⅲ increased significantly(P<0.05),while the triglyceride content decreased remarkably(P<0.05);the urea content in experimental groups Ⅰ and Ⅱ decreased obviously(P<0.05).Adding B.coagulans significantly increased the specific activity of amylase,lipase and protease in various intestinal mucosa of small intestine(P<0.05);adding B.coagulans significantly increased the content of follicle-stimulating hormone(FSH)and estradiol(E2),and significantly increased the mRNA expression of follicle stimulating hormone receptor gene(FSHR).[Conclusion]B.coagulans preparation could significantly improve the production performance of laying hens in late period of laying;appropriately enhance the immune capacity of laying hens;improve the serum biochemical indicators;increase the activity of digestive enzymes in the small intestine;and promote the release of gonadal hormone and the mRNA expression of FSHR gene in the ovary. | Xing Guanrun Lang Xinrui Wu Ji’an Lou Hongxing Liu Wenqiang Zhang Hengshuo Dong Xinyang Pan Xiaoliang Wang Youming | 2019 | Animal Husbandry and Feed Science2019，11，5： | 2 |
| 5 | Hydrothermal synthesis and electrochemical properties of dispersed LiMnPO_4wedges显示文摘 | GAO Zhi PAN Xiaoliang LI Heping | 2013 | Cryst Eng Comm2013，15，： | 1 |
| 6 | Characteristics of high Al content AlGaN grown by pulsed atomic layer epitaxy显示文摘 | Xu Pan Xiaoliang Wang Hongling Xiao Cuimei Wang Cuibai Yang Wei Li Weiying Wang Peng Jin Zhanguo Wang | 2011 | Applied Surface Science2011，，20： | 1 |
| 7 | Perovskite films with gradient bandgap for self-powered multiband photodetectors and spectrometers显示文摘Bandgap-graded materials present varying spectral responses at different positions,making them possible to be used as an alternative to photoactive materials array in multi-spectral responsive devices,thus miniaturizing the apparatus.However,the preparation of bandgap-graded materials usually requires complicated deposition process.Here we report a facile lowtemperature solution process to make films with lateral bandgap gradients,which form spontaneously via self-spreading and interdiffusion of solutions.We show lead halide perovskite films with MAPbCl_(3)-MAPbBr_(3)and MAPbBr_(3)-MAPbI_(3)gradients,which exhibit light absorption onsets ranging from 410 to 781 nm.The bandgap-graded films were used to make self-powered multiband photodetectors,which show different spectral responses at different positions without applying bias voltage.Furthermore,self-powered spectrometers were made by using the multiband photodetectors. | Chuantian Zuo Lixiu Zhang Xiyan Pan He Tian Keyou Yan Yuanhang Cheng Zhiwen Jin Chenyi Yi Xiaoliang Zhang Wu-Qiang Wu Qinye Bao Liyuan Han Liming Ding | 2023 | Nano Research2023，16，7： | 1 |
| 8 | Wavefront measurement techniques used in high power lasers显示文摘The properties of a series of phase measurement techniques,including interferometry,the Hartmann–Shack wavefront sensor,the knife-edge technique,and coherent diffraction imaging,are summarized and their performance in high power laser applications is compared.The advantages,disadvantages,and application ranges of each technique are discussed. | Haiyan Wang Cheng Liu Xiaoliang He Xingchen Pan Shenlei Zhou Rong Wu Jianqiang Zhu | 2014 | High Power Laser Science and Engineering2014，2，3： | 1 |
| 9 | Preliminary study of the internal margin of the gross tumor volume in thoracic esophageal cancer显示文摘 | Jiancheng Li Linhua Wang Xiaoliang Wang Yunhui Zhao Di Liu Cheng Chen He Ping Zhang Jianji Pan | 2012 | Cancer / Radiothérapie2012，，7： | 1 |
| 10 | DNA damage response-related immune activation signature predicts the response to immune checkpoint inhibitors: from gastrointestinal cancer analysis to pan-cancer validation显示文摘Objective: DNA damage response(DDR) deficiency has emerged as a prominent determinant of tumor immunogenicity. This study aimed to construct a DDR-related immune activation(DRIA) signature and evaluate the predictive accuracy of the DRIA signature for response to immune checkpoint inhibitor(ICI) therapy in gastrointestinal(GI) cancer.Methods: A DRIA signature was established based on two previously reported DNA damage immune response assays. Clinical and gene expression data from two published GI cancer cohorts were used to assess and validate the association between the DRIA score and response to ICI therapy. The predictive accuracy of the DRIA score was validated based on one ICI-treated melanoma and three pan-cancer published cohorts.Results: The DRIA signature includes three genes(CXCL10, IDO1, and IFI44L). In the discovery cancer cohort, DRIA-high patients with gastric cancer achieved a higher response rate to ICI therapy than DRIA-low patients(81.8% vs. 8.8%;P < 0.001), and the predictive accuracy of the DRIA score [area under the receiver operating characteristic curve(AUC) = 0.845] was superior to the predictive accuracy of PD-L1 expression, tumor mutational burden, microsatellite instability, and Epstein–Barr virus status. The validation cohort demonstrated that the DRIA score identified responders with microsatellite-stable colorectal and pancreatic adenocarcinoma who received dual PD-1 and CTLA-4 blockade with radiation therapy. Furthermore, the predictive performance of the DRIA score was shown to be robust through an extended validation in melanoma, urothelial cancer, and pan-cancer.Conclusions: The DRIA signature has superior and robust predictive accuracy for the efficacy of ICI therapy in GI cancer and pancancer, indicating that the DRIA signature may serve as a powerful biomarker for guiding ICI therapy decisions. | Junya Yan Shibo Wang Jing Zhang Qiangqiang Yuan Xianchun Gao Nannan Zhang Yan Pan Haohao Zhang Kun Liu Jun Yu Linbin Lu Hui Liu Xiaoliang Gao Sheng Zhao Wenyao Zhang Abudurousuli Reyila Yu Qi Qiujin Zhang Shundong Cang Yuanyuan Lu Yanglin Pan Yan Kong Yongzhan Nie | 2024 | Cancer Biology & Medicine2024，21，3： | 0 |
| 11 | Modulating the alloying mode in the doping-induced synthesis of Au-Pd nanowires显示文摘Heterogeneous doping is one effective strategy for synthesizing metal alloy nanowires.Herein,the heterogeneous doping processes of Pd on the ultrathin Au nanowires were systematically modulated and investigated.Au-Pd alloy nanowires with various morphologies and lattice structures can be obtained by adjusting the morphology of the precursor Au nanowires and the kinetics of the heterogeneous doping processes.The effects of the rate of Pd reduction and the concentration of the ligand oleylamine(OAm)on the Pd deposition and alloying mode were articulated.Generally,as the Pd deposition rate decreases,the Pd deposition and alloying mode switches from the island-forming Stransky–Krastanov(SK)mode to the epitaxial Frank-van der Merwe(FM)mode,and eventually to an unconventional twisting alloying mode,where the interdiffusion of Pd and Au causes drastic rearrangement of the lattice structure and formation of helical structures.The kinetics-related variation of alloying mode could also be observed in the Au-Ag nanowires,demonstrating a general design principle for the synthesis of alloy nanostructures.In addition,the electrocatalytic performance of various Au-Pd nanowires was evaluated,and the alloy nanowire formed via the SK mode was found to be an excellent electrocatalyst for oxygen reduction and ethanol oxidation. | Hui Jin Xiaoliang Wei Lecheng Zhao Jialong Yu Qiao Pan Shumin Li Qian Wang Zhaotong Yuan Dan Yang Donghui Zhao Hongyu Chen Yawen Wang | 2024 | Nano Research2024，17，4： | 0 |
| 12 | Interactive Design of Mobile Phone Interface显示文摘This topic is divided into two parts:(1) mobile phone interactive design of the status quo survey, including the mobile phone market, the use of the crowd, the use of functions, keyboard and interface analysis.(2) Mobile interactive design includes: design positioning, design requirements, innovation, tree structure, icon design. Analyze the advantages and disadvantages of the existing mobile phone interface design through the current situation investigation. Study the interface and operation of the smartphone SMS function of the students, understand the movement habits and defects of the thumb, and analyze the relationship between the keyboard and the interface. So that the existing mobile phone interface more humane, home interface under the control of the user. | Xiaoliang Pan Hongming Luo Jing Wu Zhengfei Lin | 2018 | Progress in Human Computer Interaction2018，1，1： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员