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| 1 | Evidence of the Near-Source Accumulation of the Tight Sandstone Gas in Northern Ordos Basin,North-Central China显示文摘The tight sandstone gas in Upper Paleozoic Formation of the northern Ordos Basin is a typical giant unconventional tight gas province. Evidences from geochemistry, reservoir geology and paleotectonic setting all verify that the present-day tight sandstone gas accumulation in the Ordos Basin is the result of near-source accumulation. The evidences are listed as following: tight sandstone gas is mainly distributed in the area with high gas-generating strength; gas composition was not subjected to fractionation; gas saturation significantly decreases with the distance away from the source rocks; gas isotopes suggest their origin is the same and maturity is consistent with in-place source rocks; reservoirs have experienced three types of densification digenesis, including intense compaction, siliceous cementation and calcareous cementation, which took place before the formation of a large amount of tight sandstone gas, forming tight reservoirs with low porosity and permeability, fine pore throat and great capillary resistance; the paleo-structural gradient ratio is small from the main hydrocarbon generation period to present. It is indicated the present distribution of tight sandstone gas in the northern Ordos Basin is the result of near-source and short-distance migration and accumulation. | YANG Zhi LI Qiyan WU Songtao LIN Senhu LIU Xinshen | 2017 | Acta Geologica Sinica(English Edition)2017，91，5： | 13 |
| 2 | Assimilating operational SST and sea ice analysis data into an operational circulation model for the coastal seas of China显示文摘The prediction of sea surface temperature(SST) is an essential task for an operational ocean circulation model. A sea surface heat flux, an initial temperature field, and boundary conditions directly affect the accuracy of a SST simulation. Here two quick and convenient data assimilation methods are employed to improve the SST simulation in the domain of the Bohai Sea, the Yellow Sea and the East China Sea(BYECS). One is based on a surface net heat flux correction, named as Qcorrection(QC), which nudges the flux correction to the model equation; the other is ensemble optimal interpolation(En OI), which optimizes the model initial field. Based on such two methods, the SST data obtained from the operational SST and sea ice analysis(OSTIA) system are assimilated into an operational circulation model for the coastal seas of China. The results of the simulated SST based on four experiments, in 2011, have been analyzed. By comparing with the OSTIA SST, the domain averaged root mean square error(RMSE) of the four experiments is 1.74, 1.16, 1.30 and 0.91°C, respectively; the improvements of assimilation experiments Exps 2, 3 and 4 are about 33.3%, 25.3%, and 47.7%, respectively.Although both two methods are effective in assimilating the SST, the En OI shows more advantages than the QC,and the best result is achieved when the two methods are combined. Comparing with the observational data from coastal buoy stations, show that assimilating the high-resolution satellite SST products can effectively improve the SST prediction skill in coastal regions. | JI Qiyan ZHU Xueming WANG Hui LIU Guimei GAO Shan JI Xuanliang XU Qing | 2015 | Acta Oceanologica Sinica2015，34，7： | 7 |
| 3 | Silencing the gene encoding C/EBP homologous protein lessens acute brain injury following ischemia/reperfusion显示文摘C/EBP homologous protein, an important transcription factor during endoplasmic reticulum stress, participates in cell apoptosis mediated by endoplasmic reticulum stress. Previous studies have shown that C/EBP homologous protein mediates nerve injury during Alzheimer's disease, subarachnoid hemorrhage and spinal cord trauma. In this study, we introduced C/EBP homologous protein short hairpin RNA into the brains of ischemia/reperfusion rat models via injection of lentiviral vector through the left lateral ventricle. Silencing C/EBP homologous protein gene expression significantly reduced cerebral infarction volume, decreased water content and tumor necrosis factor-α and interleukin-1β mRNA expression in brain tissues following infarction, diminished the number of TUNEL-positive cells in the infarct region, decreased caspase-3 protein content and increased Bcl-2 protein content. These results suggest that silencing C/EBP homologous protein lessens cell apoptosis and inflammatory reactions, thereby protecting nerves. | Fengzhang Wang Yuan Zhang Chunke He Tingting Wang Qiyan Piao Qun Liu | 2012 | Neural Regeneration Research2012，7，31： | 2 |
| 4 | Malaria from hyperendemicity to elimination along international borders in Yunnan, China during 2003‒2020: a case study显示文摘Background: Border malaria is one of the most intractable problems hindering malaria elimination worldwide.Movement of both the human population and anopheline mosquitoes infected with Plasmodium spp.can cause cross-border malaria transmission.The Yunnan border area was still hyperendemic for malaria in the early part of this century.The objective of this case study was to analyze the strategies,interventions and impacts of malaria control and elimination in the Yunnan border area.Main text: A total of 10,349 malaria cases and 17.1 per 10,000 person-years of annual parasite incidence(API)were reported in the border area in 2003.Based on natural village-based stratification,integrated interventions,including mass drug administration for radical cures and preventive treatment,clinically presumptive treatment of all febrile patients for malaria and indoor residual spraying or dipping bed nets with insecticides were successfully carried out from 2003 to 2013.The overall API was reduced to 0.6 per 10,000 person-years by 2013,while effective cross-border collaboration interventions dramatically reduced the malaria burden in the neighbouring border areas of Myanmar.From 2014 forward,the comprehensive strategy,including universal coverage of surveillance to detect malaria cases,a rapid response to possible malaria cases and effective border collaboration with neighbouring areas,successfully eliminated malaria and prevented reintroduction of malaria transmission in the Yunnan border area.Conclusions: In Yunnan malaria burden has successfully reduced by dynamically accurate stratification and comprehensive interventions;and then the region achieved elimination and prevented reintroduction of malaria transmission through intensive surveillance,rapid response and border collaboration.Other border areas should perform their own intervention trials to develop their own effective strategy. | Hui Liu Yaowu Zhou Yan Deng Zurui Lin Canglin Zhang Qiyan Chen Chun Wei Kaixia Duan Peng Tian Hongning Zhou Jianwei Xu | 2022 | Infectious Diseases of Poverty2022，11，3： | 1 |
| 5 | An Old Story Retold: Loss of G1 Control Defines A Distinct Genomic Subtype of Esophageal Squamous Cell Carcinoma显示文摘Esophageal squamous cell carcinoma(ESCC) has a high mortality rate. To determine the molecular basis of ESCC development, this study sought to identify characteristic genome-wide alterations in ESCC, including exonic mutations and structural alterations. The clinical implications of these genetic alterations were also analyzed. Exome sequencing and verification were performed for nine pairs of ESCC and the matched blood samples, followed by validation with additional samples using Sanger sequencing. Whole-genome SNP arrays were employed to detect copy number alteration(CNA) and loss of heterozygosity(LOH) in 55 cases, including the nine ESCC samples subjected to exome sequencing. A total of 108 non-synonymous somatic mutations(NSSMs) in102 genes were verified in nine patients. The chromatin modification process was found to be enriched in our gene ontology(GO) analysis. Tumor genomes with TP53 mutations were significantly more unstable than those without TP53 mutations. In terms of the landscape of genomic alterations, deletion of 9p21.3 covering CDKN2A/2B(30.9%), amplification of 11q13.3 covering CCND1(30.9%), and TP53 point mutation(50.9%) occurred in two-thirds of the cases. These results suggest that the deregulation of the G1 phase during the cell cycle is a key event in ESCC.Furthermore, six minimal common regions were found to be significantly altered in ESCC samples and three of them, 9p21.3, 7p11.2, and 3p12.1, were associated with lymph node metastasis. With the high correlation of TP53 mutation and genomic instability in ESCC, the amplification of CCND1, the deletion of CDKN2A/2B, and the somatic mutation of TP53 appear to play pivotal roles via G1 deregulation and therefore helps to classify this cancer into different genomic subtypes.These findings provide clinical significance that could be useful in future molecular diagnoses and therapeutic targeting. | Qiyan Wang Jian Bai Amir Abliz Ying Liu Kenan Gong Jingjing Li Wenjie Shi Yaqi Pan Fangfang Liu Shujuan Lai Haijun Yang Changdong Lu Lixin Zhang Wei Chen Ruiping Xu Hong Cai Yang Ke Changqing Zeng | 2015 | Genomics, Proteomics & Bioinformatics2015，13，4： | 1 |
| 6 | Characteristics,Types,and Prospects of Geological Sweet Sections in Giant Continental Shale Oil Provinces in China显示文摘“Sweet sections”in giant shale oil provinces are preferential fields that primarily support China to increase the reserves and production of continental shale oil.Based on the study of the geological conditions of shale oil in the continental basins in China,it was found that the shale stratum in major oil generation windows generally has higher degrees of oil and gas accumulation,and mostly contains oil.Hydrocarbon generation and reservoir capacities are the two key parameters for evaluating and optimizing favorable shale oil provinces.The evaluation index(volume of shale stratum multiplied by total organic carbon(TOC)multiplied by total porosity)for the giant continental shale oil provinces is also proposed.It is optimized that the Upper Triassic Chang 7 Member in the southcentral Ordos Basin,Lower Cretaceous Qing 1 Member in the Gulong-Changling Sag in the Songliao Basin,Middle-Lower Permian in the Junggar Basin,Da’anzhai Member of the Ziliujing Formation of Lower Jurassic in the central and northern Sichuan Basin,and Paleogene oil-rich sag in the Bohai Bay Basin are the five giant continental shale oil provinces.The word“geological sweet sections”in continental shale oil provinces of China refers to favorable shale intervals which are relatively rich in oil,with superior physical properties,and more easily modified and developed commercially under applicable economic and technological conditions.After evaluation,there are mainly two types of“geological sweet sections”of giant continental shale oil developed onshore in China.One type of“geological sweet sections”is generally mudstone with optimal physical properties or a thin tight reservoir,to which the shale oil migrates a short distance.They are medium-to-high-mature zones with a thin sandy shale stratum in the Chang 7 Member in the Ordos Basin,mixed shale stratum in the mediummature Lucaogou Formation in the Jimsar Sag,and multi-layered mixed Paleogene shale stratum in the Bohai Bay Basin.The other type of“geological sweet sections”is generally shale oil residing in various shale reservoir spaces.This type was developed in the Qing 1 Member in the Gulong Sag and Da’anzhai Member in the north-central Sichuan Basin.Free shale oil mainly occurs in shale,sandycarbonate lamina,micro-lamella structure,and micro-fractures.Layers with lamina,lamination,and micro-fractures are generally shale oil“geological sweet sections.”Starting from field tests and the construction of the“geological sweet sections”in giant continental shale oil provinces,the shale oil industry has been rapidly developing and will become an important supplement to domestic oil production in China. | Zhi Yang Caineng Zou Songtao Wu Songqi Pan Xiaoni Wang Haitao Liu Wenqi Jiang Jiarui Li Qiyan Li Xiaobing Niu Guohui Li Zhenxing Tang Xuguang Guo Dong Huang Qizhao Wei | 2022 | Journal of Earth Science2022，33，5： | 1 |
| 7 | A 2.09 Mb fragment translocation on chromosome 6 causes abnormalities during meiosis and leads to less seed watermelon显示文摘Seedlessness is a valuable agronomic trait in watermelon(Citrullus lanatus)breeding.Conventional less seed watermelons are mainly triploid,which has many disadvantages due to unbalanced genome content.Less seed watermelon can be achieved at the diploid level when certain reproductive genes are mutated or by chromosome translocation,which leads to defects during meiosis.However,the formation mechanism of diploid less seed watermelons remains largely unknown.Here,we identified a spontaneous mutant line,watermelon line“148”,which can set seeds normally when self-pollinated.A total of 148×JM F_(1) hybrid plants exhibited seed number reductions to 50.3%and 47.3%of those of the two parental lines,respectively,which are considered to be less seed.Examination of pollen viability and hybridization experiments revealed that F 1 hybrids produce semisterile pollen and ovules.Further cytological observations indicated that semisterility was a result of a reciprocal translocation of chromosomes,which exhibited one quadrivalent ring of four chromosomes at prometaphase I during meiosis.RT-qPCR analysis indirectly confirmed that the semisterile phenotype is caused by chromosome translocation rather than disruption of specific meiotic gene expression.F 2 population genetic analysis indicated that the“148”watermelon line is a homozygous translocation and that the less seed phenotype of the F_(1) hybrid is prompted by one chromosome fragment translocation.The translocated fragment was further fine mapped to a 2.09 Mb region on chromosome 6 by whole-genome resequencing and genetic map cloning procedures.Our work revealed that a 2.09Mb chromosome fragment translocation on chromosome 6,causing meiotic defects at metaphase I during meiosis,leads to diploid less seed watermelon.Our findings provide a new promising method for less seed watermelon breeding at the diploid level,as well as a fragment size reference for breeding less seed watermelon through artificially induced chromosome translocation. | Shujuan Tian Jie Ge Gongli Ai Jiao Jiang Qiyan Liu Xiner Chen Man Liu Jianqiang Yang Xian Zhang Li Yuan | 2021 | Horticulture Research2021，8，1： | 1 |
| 8 | Magnetic chitosan nanocomposites: A useful recyclable tool for heavy metal ion removal显示文摘 | Liu Xiaowang Hu Qiyan Fang Zhen | 2009 | Langmuir2009，25，1： | 1 |
| 9 | Response of Gafchromic EBT2 Films to Carbon Ions of 200 MeV/u显示文摘 | Liu Xinguo Li Qiang Dai Zhongying Huang Qiyan | 2011 | IMP & HIRFL Annual Report2011，，1： | 0 |
| 10 | 3-41 Bio-audiovisual Feedback Breathing Guidance Technique for Synchrotron-based Ion Beam Delivery显示文摘Based on the periodic synchrotron-based beam delivery,a bio-audiovisual feedback breathing guidance technique has been developed to mitigate the interplay between target motion and dynamic beam delivery for ion beam therapy,in which variable beam extraction and generation of individualized breathing guidance curve are two key factors.Shown in Fig.1 is the schematic diagram of the breathing guidance technique.Through the simulations with 15 healthy volunteers for the breathing guidance technique,we found not only the treatment efficiency of synchrotron-based pulsed ion beam could be increased effectively,but also the residual movement of respiration during gating window could be reduced. | Li Qiang He Pengbo Liu Xinguo Dai Zhongying Ma Yuanyuan Shen Guosheng Yan Yuanlin Huang Qiyan Fu Tingyan | 2014 | IMP & HIRFL Annual Report2014，，1： | 0 |
| 11 | 3-42 Fast Calibration of EBT Films in Scanned Ion Therapy显示文摘In the quality assurance of photon and ion beam radiotherapy with EBT films, the dose response curves of thesefilms should previously be calibrated. The traditional calibration method is to cut a big piece of EBT film intomany small ones, which are separately irradiated with different doses. Then these small EBT films are digitizedwith a commercial flatbed color scanner to get the net optical density (netOD) values, which are fitted against thedoses. In this work, we present a fast calibration method of EBT films in scanned ion radiotherapy. | Liu Xinguo Li Qiang Dai Zhongying He Pengbo Huang Qiyan Yan Yuanlin | 2014 | IMP & HIRFL Annual Report2014，，1： | 0 |
| 12 | 3-44 Monte Carlo Simulation Study on Optimizing the Active Beam Delivery System at HIRFL显示文摘To obtain carbon ion beam suitable for the active spot scanning beam delivery system at the Heavy Ion ResearchFacility in Lanzhou (HIRFL), the Monte Carlo (MC) program SHIELD-HIT12A was used to study the influencesof beam delivery distance and structure period of mini ridge filter on full width at the half maximum (FWHM) ofbeam spot and dose flatness at the iso-center of the treatment room. | Yan Yuanlin Liu Xingguo Dai Zhongying Ma Yuanyuan Huang Qiyan He Pengbo Shen Guosheng Fu Tingyan Li Qiang | 2014 | IMP & HIRFL Annual Report2014，，1： | 0 |
| 13 | Estimating Costs of the HIV Comprehensive Intervention Using the Spectrum Model--China,2015-2019显示文摘Introduction:In order to facilitate human immunodeficiency virus(HIV)treatment and prevention,the resource needs for HIV national strategic planning in developing regions were estimated based on Spectrum,the universal HIV costeffectiveness analysis software.Methods:Based on the theoretical framework of Spectrum,the study developed a cost measurement tool for HIV,and calculated the cost of HIV prevention and control in 6 sampled cities in China during 2015–2019 using the Spectrum model.Results:From 2015 to 2019,the average annual costs for HIV prevention and control for Shijiazhuang,Yantai,Ningbo,Zhenjiang,Foshan,and Wuxi cities were 46.78,47.55,137.49,24.73,74.37,and 58.30 million Chinese yuan(CNY),respectively.The per capita costs were 4.37,6.73,17.33,7.77,17.56,and 8.91 CNY,respectively.In terms of the cost structure,the ratio of preventive intervention funds to therapeutic intervention funds(antiviral treatment)varied in sampled cities.Discussion:Developing comprehensive and systematic HIV fund calculation methods can provide a research basis for rational resource allocation in the field of HIV. | Youran Zhang Lili Wang Zhen Jiang Hongjing Yan Xiaoxia Liu Jing Gu Guoyong Wang Xiaosong Cheng Qiyan Leng Qisui Long Zimian Liang Jing Wang Liang Liang Yanchao Qiu Lin Chen Hang Hong | 2022 | China CDC weekly2022，4，25： | 0 |
| 14 | Current state and future of co-inhibitory immune checkpoints for the treatment of glioblastoma显示文摘In the interaction between a tumor and the immune system,immune checkpoints play an important role,and in tumor immune escape,co-inhibitory immune checkpoints are important.Immune checkpoint inhibitors(ICIs)can enhance the immune system's killing effect on tumors.To date,impressive progress has been made in a variety of tumor treatments;PD1/PDL1 and CTLA4 inhibitors have been approved for clinical use in some tumors.However,glioblastoma(GBM)still lacks an effective treatment.Recently,a phase III clinical trial using nivolumab to treat recurrent GBM showed no significant improvement in overall survival compared to bevacizumab.Therefore,the use of immune checkpoints in the treatment of GBM still faces many challenges.First,to clarify the mechanism of action,how different immune checkpoints play roles in tumor escape needs to be determined;which biomarkers predict a benefit from ICIs treatment and the therapeutic implications for GBM based on experiences in other tumors also need to be determined.Second,to optimize combination therapies,how different types of immune checkpoints are selected for combined application and whether combinations with targeted agents or other immunotherapies exhibit increased efficacy need to be addressed.All of these concerns require extensive basic research and clinical trials.In this study,we reviewed existing knowledge with respect to the issues mentioned above and the progress made in treatments,summarized the state of ICIs in preclinical studies and clinical trials involving GBM,and speculated on the therapeutic prospects of ICIs in the treatment of GBM. | Shaoping Shen Ling Chen Jialin Liu Lin Yang Mengna Zhang Lingxiong Wang Rong Zhang Yasushi Uemura Qiyan Wu Xinguang Yu Tianyi Liu | 2020 | Cancer Biology & Medicine2020，17，3： | 0 |
| 15 | Air to fuel:Direct capture of CO_(2)from air and in-situ solar-driven conversion into syngas via Ni_(x)/NaA nanomaterials显示文摘Ever-increasing CO_(2)emissions and atmospheric concentration mainly due to the burning of traditional fossil fuels have caused severe global warming and climate change problems.Inspired by nature’s carbon cycle,we propose a novel dual functional catalyst-sorbent to tackle energy and environmental problems simultaneously via direct capture of CO_(2)from air and in-situ solar-driven conversion into clean fuels.Economically and operationally advantageous,the planned coupling reaction can be carried out in a single reactor without the requirement for an extra trapping device.The great CO_(2)capture and conversion performance in an integrated step is shown by the CO_(2)capacity of up to 0.38 mmol·g^(−1)for adsorption from 500 ppm CO_(2)at 25℃and the CO_(2)conversion rate of up to 95%.Importantly,the catalyst-sorbent is constituted of a nonprecious metal Ni catalyst and an inexpensive commercially available CO_(2)sorbent,viz,zeolite NaA.Furthermore,this designed dual functional material also exhibits outstanding stability performance.This work offers a novel pathway of capturing CO_(2)in the air at room temperature and converting it by CH4 into fuel,contributing to the new era of carbon neutrality. | Cheng Tian Xianglei Liu Chenxi Liu Shaoyang Li Qiyan Li Nan Sun Ke Gao Zhixing Jiang Kun Chang Yimin Xuan | 2023 | Nano Research2023，16，8： | 0 |
| 16 | Assimilating OSTIA SST into regional modeling systems for the Yellow Sea using ensemble methods显示文摘The effects of sea surface temperature(SST) data assimilation in two regional ocean modeling systems were examined for the Yellow Sea(YS). The SST data from the Operational Sea Surface Temperature and Sea Ice Analysis(OSTIA) were assimilated. The National Marine Environmental Forecasting Center(NMEFC) modeling system uses the ensemble optimal interpolation method for ocean data assimilation and the Kunsan National University(KNU) modeling system uses the ensemble Kalman filter. Without data assimilation, the NMEFC modeling system was better in simulating the subsurface temperature while the KNU modeling system was better in simulating SST. The disparity between both modeling systems might be related to differences in calculating the surface heat flux, horizontal grid spacing, and atmospheric forcing data. The data assimilation reduced the root mean square error(RMSE) of the SST from 1.78°C(1.46°C) to 1.30°C(1.21°C) for the NMEFC(KNU) modeling system when the simulated temperature was compared to Optimum Interpolation Sea Surface Temperature(OISST) SST dataset. A comparison with the buoy SST data indicated a 41%(31%) decrease in the SST error for the NMEFC(KNU) modeling system by the data assimilation. In both data assimilative systems, the RMSE of the temperature was less than 1.5°C in the upper 20 m and approximately 3.1°C in the lower layer in October. In contrast, it was less than 1.0°C throughout the water column in February. This study suggests that assimilations of the observed temperature profiles are necessary in order to correct the lower layer temperature during the stratified season and an ocean modeling system with small grid spacing and optimal data assimilation method is preferable to ensure accurate predictions of the coastal ocean in the YS. | JI Xuanliang KWON Kyung Man CHOI Byoung-Ju LIU Guimei PARK Kwang-Soon WANG Hui BYUN Do-Seong LI Yun JI Qiyan ZHU Xueming | 2017 | Acta Oceanologica Sinica2017，36，3： | 0 |
| 17 | HY-1C Coastal Zone Imager observations of the suspended sediment content distribution details in the sea area near Hong Kong-Zhuhai-Macao Bridge in China显示文摘The impacts of the Hong Kong-Zhuhai-Macao Bridge(HKZMB)on suspended sediment content(SSC)were analysed in the Zhujiang River Estuary based on data from HY-1C,which was launched in September 2018 in China,carrying Coastal Zone Imager(CZI)and Chinese Ocean Color and Temperature Scanner on it.A new SSC inversion model was established based on the relationship between in-situ SSC and the remote sensing reflectance in red and near-infrared bands of CZI image.HY-1C satellite data obtained from October to December 2019 were applied to retrieve SSC in the Zhujiang River Estuary.The results show that SSC around the HKZMB is ranging from 20 mg/L to 95 mg/L.SSC change obviously on two sides of the bridge.During flooding and ebbing period,SSC increases obviously downstream of the bridge.SSC difference between upstream and downstream is ranging from 5 mg/L to 20 mg/L.Currents flowing across the HKZMB,the change trend of SSC in most places upstream and downstream is almost the same that SSC downstream of the bridge is higher than SSC upstream.The tidal currents interact with bridge piers,inducing vortexes downstream,leading the sediment to re-suspend downstream of the bridge piers.Other factors,including seafloor topography and wind,can also contribute to the distribution of SSC in the Zhujiang River Estuary. | Lina Cai Minrui Zhou Xiaojun Yan Jianqiang Liu Qiyan Ji Yuxiang Chen Juncheng Zuo | 2022 | Acta Oceanologica Sinica2022，41，11： | 0 |
| 18 | Use of Qishen granule for the treatment of heart failure: A systematic review and meta-analysis of animal studies显示文摘Objective:To evaluate the effect of Qishen granule(QSG)on heart failure(HF)and the potential mechanisms involved in animal models.Methods:Studies of QSG in animals with HF were identified by searches of eight databases up to August 1,2019.Two authors independently reviewed each study and the Collaborative Approach to Metaanalysis and Review of Animal Data from Experimental Studies 10-item checklist was used for quality assessment.The primary outcomes were indicators of left ventricular ejection fraction and/or left ventricular fractional shortening.The secondary outcome measures were ventricular structure,hemodynamics,myocardial injury-related indicators,and the mechanisms whereby QSG ameliorates HF.A metaanalysis was performed and all the data were analyzed using RevMan 5.3 software.Results:Thirteen studies containing a total of 240 animals met the criteria for the meta-analysis.The quality score of the studies ranged from three to six points.The meta-analysis showed a significant effect of QSG to improve cardiac function,inhibit ventricular remodeling,improve circulation,and attenuate myocardial injury.The possible mechanisms was identified to be suppression of the renin-angiotensinaldosterone system,which has anti-fibrotic,anti-apoptotic,anti-inflammatory,and anti-oxidative effects in the myocardium,the prevention of calcium overload,and the promotion of myocardial energy metabolism.Conclusion:Our review shows that QSG has a cardioprotective effect in animal models of CHF.However,due to the relatively poor quality of the included studies and the differences between humans and animal models,the results should be interpreted with caution. | Junjie Liu Shuangjie Yang Wei Wang Yili Zhang Qiyan Wang Xiaoli Sun Nannan Tan Kangjia Du Yong Wang Huihui Zhao | 2020 | Journal of Traditional Chinese Medical Sciences2020，7，2： | 0 |
| 19 | Distribution and modes of occurrence of uranium in coals of Eastern Yunnan,China显示文摘Uranium is an environmentally hazardous element,and is commonly present at trace levels(2.4 μg/g for world coals)in coal deposits.However,selected coal deposits could be highly enriched in uranium.In this study,15 coal samples were collected from Eastern Yunnan coal deposits,China,aiming to characterize the distribution and the occurrence of uranium in those coals.In studied samples,uranium content varied from 0.36 to 8.28 μg/g,with an average value of 3.76 lg/g.Generally,uranium content in coals from northern coal mines(3.02±2.44 μg/g,n=5)were lower than it in southern coal mines(4.13±2.30 μg/g,n=10).Uranium in coal samples showed no obvious correlation with total sulfur,whereas was positively correlated with ash yield.The results of sequential chemical extraction procedure confirm that organic-bound is the dominant occurrence of uranium.The slight enrichment of uranium in studied coals was probably attributed to sedimentation processes,hydrological conditions and tectonic structure of the coal deposits. | Xin Wang Qiyan Feng Qingjun Meng Fei Liu Qihang Cao Guijian Liu | 2021 | International Journal of Coal Science & Technology2021，8，6： | 0 |
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