|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | China's lakes at present:Number,area and spatial distribution显示文摘Based on 11004 satellite images from CBERS CCD and Landsat TM/ETM,changes in the spatial characteristics of all lakes in China were determined following pre-established interpretation rules.This dataset was supported by 6843 digital raster images(1:100000 and 1:50000),a countrywide digital vector dataset(1:250000),and historical literature.Comparative data were corrected for seasonal variations using precipitation data.There are presently 2693 natural lakes in China with an area greater than 1.0 km2,excluding reservoirs.These lakes are distributed in 28 provinces,autonomous regions and municipalities and have a total area of 81414.6 km2,accounting for-0.9% of China's total land area.In the past 30 years,the number of newly formed and newly discovered lakes with an area greater than 1.0 km2 is 60 and 131,respectively.Conversely,243 lakes have disappeared in this time period. | MA RongHua YANG GuiShan DUAN HongTao JIANG JiaHu WANG SuMin FENG XueZhi LI AiNong KONG FanXiang XUE Bin WU JingLu LI ShiJie | 2011 | Science China Earth Sciences2011，54，2： | 79 |
| 2 | Dating of the Karakorum Strike-slip Fault显示文摘This paper mainly discusses the timing of the Karakorum strike-slip fault, and gives a brief introduction of its structures, offset, and deformational style. This fault strikes NNW-SSE. Asymmetrical folds, stretching lineation, S-C fabrics, feldspar and quartz (-porphyroclasts, domino structure, shear cleavages and faults in the fault zone are products of tectonic movements. They all indicate a dextral slip sense of faulting. Mylonitic bands are widely developed along this fault. Phengite appears, indicating rather high deformational pressure. Geochronological data indicate that the Karakorum strike-slip faulting occurred from 6.88(0.36 to 8.75(0.25 Ma. The cumulative displacement from Muztag Ata to Muji is about 135 km. | ZHOU Yong, XU Ronghua, YAN Yuehua, PAN Yusheng,Tsanyao Frank YANG, Wei LO and WU Chunming Laboratory of Lithosphere Tectonic Evolution, Institute of Geology and Geophysics, Chinese Academy of Sciences, Beijing 100029Department of Geology, National Taiwan University, 245 Choushan Road, Taipei 106-17, TaiwanDepartment of Geology, Chinese Culture University, Hwa-kang, Yang-Ming-Shan, Taipei, Taiwan Institute of Geology, Chinese Academy of Geological Sciences, Beijing 100037 | 2001 | Acta Geologica Sinica(English Edition)2001，75，1： | 12 |
| 3 | Humoral immune response to circulating SARS-CoV-2 variants elicited by inactivated and RBD-subunit vaccines显示文摘SARS-CoV-2 variants could induce immune escape by mutations on the receptor-binding domain(RBD)and N-terminal domain(NTD).Here we report the humoral immune response to circulating SARS-CoV-2 variants,such as 501Y.V2(B.1.351),of the plasma and neutralizing antibodies(NAbs)elicited by CoronaVac(inactivated vaccine),ZF2001(RBD-subunit vaccine)and natural infection.Among 86 potent NAbs identified by high-throughput single-cell VDJ sequencing of peripheral blood mononuclear cells from vaccinees and convalescents,near half anti-RBD NAbs showed major neutralization reductions against the K417N/E484K/N501Y mutation combination,with E484K being the dominant cause.VH3-53/VH3-66 recurrent antibodies respond differently to RBD variants,and K417N compromises the majority of neutralizing activity through reduced polar contacts with complementarity determining regions.In contrast,the 242–244 deletion(242–244Δ)would abolish most neutralization activity of anti-NTD NAbs by interrupting the conformation of NTD antigenic supersite,indicating a much less diversity of anti-NTD NAbs than anti-RBD NAbs.Plasma of convalescents and CoronaVac vaccinees displayed comparable neutralization reductions against pseudo-and authentic 501Y.V2 variants,mainly caused by E484K/N501Y and 242–244Δ,with the effects being additive.Importantly,RBD-subunit vaccinees exhibit markedly higher tolerance to 501Y.V2 than convalescents,since the elicited anti-RBD NAbs display a high diversity and are unaffected by NTD mutations.Moreover,an extended gap between the third and second doses of ZF2001 leads to better neutralizing activity and tolerance to 501Y.V2 than the standard three-dose administration.Together,these results suggest that the deployment of RBD-vaccines,through a third-dose boost,may be ideal for combating SARS-CoV-2 variants when necessary,especially for those carrying mutations that disrupt the NTD supersite. | Yunlong Cao Ayijiang Yisimayi Yali Bai Weijin Huang Xiaofeng Li Zhiying Zhang Tianjiao Yuan Ran An Jing Wang Tianhe Xiao Shuo Du Wenping Ma Liyang Song Yongzheng Li Xiang Li Weiliang Song Jiajing Wu Shuo Liu Xuemei Li Yonghong Zhang Bin Su Xianghua Guo Yangyang Wei Chuanping Gao Nana Zhang Yifei Zhang Yang Dou Xiaoyu Xu Rui Shi Bai Lu Ronghua Jin Yingmin Ma Chengfeng Qin Youchun Wang Yingmei Feng Junyu Xiao Xiaoliang Sunney Xie | 2021 | Cell Research2021，31，7： | 12 |
| 4 | Infection Control after Surgical Management of Complex Retinal Detachment by Vitrectomy显示文摘Purpose:To investigate the risk factors and infection control after vitrectomy.Methods:.By analyzing the risk factors of surgical infection following vitrectomy,.a sound surgical cooperation workflow was established..A system of equipment cleaning,.disinfection, and quarantine was set up. The use of sterile implants and disposable consumables was subject to strict management and the system of operation room environment and sterile technique were strengthened.Results: Infection control during perioperative period was improved and the nursing staff's perceptions of preventing surgical infection were enhanced,.which guaranteed the safety of vitrectomy and controlled the infection rate to levels as low as0.035%.Conclusion: Proper management of vitrectomy plays a pivotal role in the prevention of post-vitrectomy surgical infection. | Jingyi Lin Ronghua Ye Suhong Wu Mingse Lin | 2013 | Eye Science2013，28，3： | 10 |
| 5 | Humoral immunogenicity and reactogenicity of CoronaVac or ZF2001 booster after two doses of inactivated vaccine显示文摘Dear Editor,COVID-19 vaccination campaigns are being conducted in countries worldwide,and 47.4% of the world population has received at least one dose of a COVID-19 vaccine.1 Although vaccination has shaped COVID-19 epidemic curves,waning antibody levels and relatively short-duration protection provided by current COVID-19 vaccines have been observed,especially against SARS-CoV-2 variants of concern(VOCs)and among older individuals. | Yunlong Cao Xiaohua Hao Xi Wang Qianhui Wu Rui Song Dong Zhao Weiliang Song Yao Wang Ayijiang Yisimayi Wei Wang Juan Du Hongjie Yu Xiaoliang Sunney Xie Ronghua Jin | 2022 | Cell Research2022，32，1： | 8 |
| 6 | Microstructure and Mechanical Properties of 45 vol.%SiC_p/7075Al Composite显示文摘Microstructure and mechanical behavior of high volume content Si Cp/7xxx Al composites have not been explored yet. Therefore, in the present work, 45 vol.% SiC p/7075 Al composite has been prepared by pressure infiltration method. High density dislocations were found around Si C/Al interface in SiC p/7075 Al composite after water-quenching and aging treatment. Fine dispersed nano-η′ phases were observed after the aging treatment. Adverse to other Si Cp/Al composites prepared by the pressure infiltration method,an interface layer was observed between SiC particles and Al matrix. Furthermore, high-resolution transmission electron microscopy(HRTEM) observation indicated that this interface layer was coherent/semicoherent with that of the SiC particles. 45 vol.% SiC p/7075 Al composite demonstrated high tensile strength(630 MPa) and micro-ductility. Compared to aged Si Cp/2024 Al composite, the aged Si Cp/7075 Al composite showed an increase of about 200% in the tensile strain and 90% in the tensile strength, respectively.It is speculated that nano-η′ phases in the Al matrix significantly contributed to the strengthening effect while the interface layer between Si C and Al matrix might be beneficial to the strength and plasticity of Si Cp/7075 Al composite. | Ziyang Xiu Wenshu Yang Ronghua Dong Murid Hussain Longtao Jiang YongXing Liu Gaohui Wu | 2015 | Journal of Materials Science & Technology2015，31，9： | 7 |
| 7 | Immunity-and-matrix-regulatory cells derived from human embryonic stem cells safely and effectively treat mouse lung injury and fibrosis显示文摘Lung injury and fibrosis represent the most significant outcomes of severe and acute lung disorders,including COVID-19.However,there are still no effective drugs to treat lung injury and fibrosis.In this study,we report the generation of clinical-grade human embryonic stem cells(hESCs)-derived immunity-and matrix-regulatory cells(IMRCs)produced under good manufacturing practice requirements,that can treat lung injury and fibrosis in vivo.We generate IMRCs by sequentially differentiating hESCs with serum-free reagents.IMRCs possess a unique gene expression profile distinct from that of umbilical cord mesenchymal stem cells(UCMSCs),such as higher expression levels of proliferative,immunomodulatory and anti-fibrotic genes.Moreover,intravenous delivery of IMRCs inhibits both pulmonary inflammation and fibrosis in mouse models of lung injury,and significantly improves the survival rate of the recipient mice in a dose-dependent manner,likely through paracrine regulatory mechanisms.IMRCs are superior to both primary UCMSCs and the FDA-approved drug pirfenidone,with an excellent efficacy and safety profile in mice and monkeys.In light of public health crises involving pneumonia,acute lung injury and acute respiratory distress syndrome,our findings suggest that IMRCs are ready for clinical trials on lung disorders. | Jun Wu Dingyun Song Zhongwen Li Baojie Guo Yani Xiao Wenjing Liu Lingmin Liang Chunjing Feng Tingting Gao Yanxia Chen Ying Li Zai Wang Jianyan Wen Shengnan Yang Peipei Liu Lei Wang Yukai Wang Liang Peng Glyn Nigel Stacey Zheng Hu Guihai Feng Wei Li Yan Huo Ronghua Jin Ng Shyh-Chang Qi Zhou Liu Wang Baoyang Hu Huaping Dai Jie Hao | 2020 | Cell Research2020，30，9： | 7 |
| 8 | A Web-based visual analytics system for real estate data显示文摘Real estate is an important industry in most countries.However,the analysis of the real estate market is very challenging as the data are high dimensional and have complex spatial and temporal patterns.In this paper,we present a novel Web-based visual analytics system,which integrates state-of-the-art interactive visualizations to enable end users to create their own visualizations and gain insight into the real estate market.The system is implemented using the new features in HTML5,which are natively supported in current browsers.We adopt a coordinated view design in our system consisting of four major components:a map view to show the geographical information of houses,a stacked graph view to show the evolution of house sales over time,a pixel-bar view to visualize multiple attributes of houses,and a treemap view to present the hierarchical structure of the data.Novel clutter reduction methods and rich user interactions are further proposed to enhance the flexibility and analytical ability of the whole system.We have applied our system to real property market data and obtained some interesting findings.Moreover,feedback from the end users of our system is very positive. | SUN GuoDao LIANG RongHua WU FuLi QU HuaMin | 2013 | Science China(Information Sciences)2013，56，5： | 3 |
| 9 | Dual-Branch-UNet: A Dual-Branch Convolutional Neural Network for Medical Image Segmentation显示文摘In intelligent perception and diagnosis of medical equipment,the visual and morphological changes in retinal vessels are closely related to the severity of cardiovascular diseases(e.g.,diabetes and hypertension).Intelligent auxiliary diagnosis of these diseases depends on the accuracy of the retinal vascular segmentation results.To address this challenge,we design a Dual-Branch-UNet framework,which comprises a Dual-Branch encoder structure for feature extraction based on the traditional U-Net model for medical image segmentation.To be more explicit,we utilize a novel parallel encoder made up of various convolutional modules to enhance the encoder portion of the original U-Net.Then,image features are combined at each layer to produce richer semantic data and the model’s capacity is adjusted to various input images.Meanwhile,in the lower sampling section,we give up pooling and conduct the lower sampling by convolution operation to control step size for information fusion.We also employ an attentionmodule in the decoder stage to filter the image noises so as to lessen the response of irrelevant features.Experiments are verified and compared on the DRIVE and ARIA datasets for retinal vessels segmentation.The proposed Dual-Branch-UNet has proved to be superior to other five typical state-of-the-art methods. | Muwei Jian Ronghua Wu Hongyu Chen Lanqi Fu Chengdong Yang | 2023 | Computer Modeling in Engineering & Sciences2023，，10： | 2 |
| 10 | Study of the location of testing area in residual stress measurement by Moiré interferometry combined with hole-drilling method显示文摘This paper investigates the effect of the location of testing area in residual stress measurement by Moiréinterferometry combined with hole-drilling method.The selection of the location of the testing area is analyzed from theory and experiment.In the theoretical study,the factors which affect the surface released radial strainεr were analyzed on the basis of the formulae of the hole-drilling method,and the relations between those factors andεr were established.By combining Moiréinterferometry with the hole-drilling method,the residual stress of interference-fit specimen was measured to verify the theoretical analysis.According to the analysis results,the testing area for minimizing the error of strain measurement is determined.Moreover,if the orientation of the maximum principal stress is known,the value of strain will be measured with higher precision by the Moiréinterferometry method. | QIN Le XIE HuiMin ZHU RongHua WU Dan CHE ZhiGang ZOU ShiKun | 2014 | Science China(Physics,Mechanics & Astronomy)2014，57，4： | 2 |
| 11 | Co-culture of Schwann cells and endothelial cells for synergistically regulating dorsal root ganglion behavior on chitosan-based anisotropic topology for peripheral nerve regeneration显示文摘Background:Anisotropic topologies are known to regulate cell-oriented growth and induce cell differentiation,which is conducive to accelerating nerve regeneration,while co-culture of endothelial cells(ECs)and Schwann cells(SCs)can significantly promote the axon growth of dorsal root ganglion(DRG).However,the synergistic regulation of EC and SC co-culture of DRG behavior on anisotropic topologies is still rarely reported.The study aims to investigate the effect of anisotropic topology co-cultured with Schwann cells and endothelial cells on dorsal root ganglion behavior for promoting peripheral nerve regeneration.Methods:Chitosan/artemisia sphaerocephala(CS/AS)scaffolds with anisotropic topology were first prepared using micro-molding technology,and then the surface was modified with dopamine to facilitate cell adhesion and growth.The physical and chemical properties of the scaffolds were characterized through morphology,wettability,surface roughness and component variation.SCs and ECs were co-cultured with DRG cells on anisotropic topology scaffolds to evaluate the axon growth behavior.Results:Dopamine-modified topological CS/AS scaffolds had good hydrophilicity and provided an appropriate environment for cell growth.Cellular immunofluorescence showed that in contrast to DRG growth alone,co-culture of SCs and ECs could not only promote the growth of DRG axons,but also offered a stronger guidance for orientation growth of neurons,which could effectively prevent axons from tangling and knotting,and thus may significantly inhibit neurofibroma formation.Moreover,the co-culture of SCs and ECs could promote the release of nerve growth factor and vascular endothelial growth factor,and up-regulate genes relevant to cell proliferation,myelination and skeletal development via the PI3K-Akt,MAPK and cytokine and receptor chemokine pathways.Conclusions:The co-culture of SCs and ECs significantly improved the growth behavior of DRG on anisotropic topological scaffolds,which may provide an important basis for the development of nerve grafts in peripheral nerve regeneration. | Tiantian Zheng Linliang Wu Shaolan Sun Jiawei Xu Qi Han Yifan Liu Ronghua Wu Guicai Li | 2022 | Burns & Trauma2022，10，1： | 2 |
| 12 | Seasonal fluxes and source variation of organic carbon transported by two major Chinese Rivers: The Yellow River and Changjiang (Yangtze) River显示文摘 | Wang Xuchen Ma Haiqing Li Ronghua Song Zhensu Wu Jinping | 2012 | EN2012，，2： | 2 |
| 13 | Characterization of a New Gene wx2 in Toxoplasma gondii显示文摘用杂交技术,我们准备了单音的同种细胞的抗体(Mab ) 对 Toxoplasma gondii 的 7C3-C3。保护测试证明蛋白质(Mab7C3-C3 ) 禁止了 T 的侵略和增长。在 HeLa 房间的 gondii RH 紧张。被动转移测试显示抗体显著地延长了质问老鼠的幸存时间。抗体能被用于 T.gondii 的传播抗原的察觉,这也被显示出。在屏蔽 T 的免疫以后。有 Mab7C3-C3 的 gondii tachyzoite cDNA 图书馆,新基因 wx2of T。gondii 被获得。Immunofluorescence 分析证明 WX2 蛋白质是寄生虫的定位的在膜。核苷酸顺序比较显示出 28% 身份到钙隧道 alpha-1E 单位并且与表面抗原分享了在一些保守残余的相关顺序。然而,没有火柴在蛋白质数据库被发现。因此,它是在在 T 的膜上编码功能的蛋白质的 T.gondii 的未知基因。gondii。因为对 T 有部分保护的效果被显示了。gondii 感染并且作为传播抗原被释放,它能为新药是为疫苗或一个新奇目标的一个候选人分子。 | Xiang WU Qiong ZHANG Kui TAN Ronghua XIE Jiubo FAN Hengping SHU Shiping WANG | 2007 | Acta Biochimica et Biophysica Sinica2007，39，7： | 2 |
| 14 | Interleukin-10 inhibits the expression of nuclear factor kappa B in rats with cerebral ischemia显示文摘BACKGROUND: Plenty of studies have demonstrated that inflammatory reaction is involved in ischemic cerebral damage, and the expression of inflammatory cytokines can be observed at the initial sites of cerebral damage at early period, including interleukin-6, interleukin-8, etc., which are all the target gene products of nuclear factor kappa B (NF-κB). The process of ischemic damage can be affected by adjusting and controlling NF-κB activity via multi-links. OBJECTIVE: To investigate the inhibitory effect of interleukin-10 on the expression of NF-κB in the ischemic sites of rats with focal cerebral ischemia in rats and its molecular mechanisms. DESIGN: A randomized and controlled animal trial. SETTING: Department of Neurology, the Affiliated Union Hospital of Fujian Medical University. MATERIALS: Thirty-two adult male Sprague-Dawley rats weighing (250±30) g were used. NF-κB p65 (RelA) rabbit anti-rat monoclonal primary antibody was the product of Neomarkers Company; Immunohistochemical kit of the SP two-step method was purchased from Beijing Zhongshan Biotechnology Co., Ltd. METHODS: The experiment was carried out in the Affiliated Union Hospital of Fujian Medical University from August 2005 to April 2006. The rats were randomly assigned into sham-operated group, middle cerebral artery occlusion (MCAO) group, vehicle-treated group and interleukin-10 treated group, 8 rats in each group. Focal cerebral ischemia was induced by occlusion of the middle cerebral artery as previously described. Rats in the MCAO group were anesthetized intraperitoneally, thyroid was bluntly dissected. Right common, external and internal carotid arteries were isolated, the trunk of external carotid artery was ligated and freed, an artery clamp was placed at the internal carotid artery, then a 'V' shape incision was made at the free section of external carotid artery, filament was inserted for a depth of (18.5±0.5) mm. The rats in the sham-operated group were given the same treatments with the exception of filament insertion. After the successful model establishment for 1 hour, the rats in the interleukin-10 treated group were injected with human recombinant interleukin-10 (1 μg) via lateral ventricle, whereas those in the vehicle-treated group were injected with 5 mol/L NaP (5 μL). The rectal temperature of rats were kept at about 37 ℃ with heating lamps throughout the operation. Twenty-four hours after MCAO, the rats were examined for neurological deficits. Only those animals that scored at 1-3 points were utilized. The rats were decapitated at 24 hours postoperatively. The expression of NF-κB p65 in peri-infarct core was detected immunohistochemically. The percentage of NF-κB p65 subunit positive cells in 1 000 cells was calculated. MAIN OUTCOME MEASURES: Expression of NF-κB p65 in peri-infarct core; Percentage of NF-κB p65 subunit positive cells. RESULTS: All the 32 rats were involved in the analysis of results. NF-κB p65 expressed in cytoplasm and some nuclei. It was expressed all in cytoplasm in the sham-operated group, and partly expressed in the nucleus after cerebral ischemia. Small amounts of NF-κB p65 positive neurocytes were observed in the sham-operated group[(3.7±0.6)%], those were obviously increased in the MCAO group [(15.4±3.7)%, P < 0.01]. NF-κB p65 positive neurocytes were significantly reduced in the interleukin-10 treated group as compared with those in the vehicle-treated groups [(12.1±2.2)%, (15.5±3.6)%, P < 0.05]. CONCLUSION: Interleukin-10 injected via lateral ventricle can effectively inhibit the expression of NF-κB p65 in the peri-ischemic core in rats, and block the gene transcription involved in the inflammatory cascade reaction. | Zhihua Wu Nan Liu Houwei Du Ronghua Chen An Zheng Huapin Huang | 2006 | Neural Regeneration Research2006，1，9： | 2 |
| 15 | Design of sonar transducer based on the laser-induced sound显示文摘一种声纳变换器的一个图案被介绍。一个试验性的系统为基于导致激光的故障和水泡摆动生产健全信号被开发。力量光谱和歧义功能被分析。范围分辨率和健全信号的 Doppler 分辨率常数是坚定的。它基本上在理论被证明声纳变换器的范围决定和择向性很高。变换器能是高分辨率的声纳的健全来源。 | WANG Yuhong WANG Jiang'an ZONG Siguang WU Ronghua | 2009 | Chinese Journal of Acoustics2009，28，3： | 1 |
| 16 | Detection of sensitive soil properties related to non-point phosphorus pollution by integrated models of SEDD and PLOAD显示文摘 | Lin Chen Wu Zhipeng Ma Ronghua | 2016 | Ecological Indicators2016，60，： | 1 |
| 17 | Radiometric Cross-Calibration for Multiple Sensors with the Moon as an Intermediate Reference显示文摘The instrument cross-calibration is an effective way to assess the quality of satellite data. In this study, a new method is proposed to cross-calibrate the sensors among satellite instruments by using a RObotic Lunar Observatory(ROLO) model and Apollo sample reflectance in reflective solar bands(RSBs). The ROLO model acts as a transfer radiometer to bridge between the instruments. The reflective spectrum of the Apollo sample is used to compensate for the difference in the instrument's relative spectral responses(RSRs). In addition, the double ratio between the observed lunar irradiance and the simulated lunar irradiance is used to reduce the difference in instrument lunar viewing and illumining geometry. This approach is applied to the Moderate Resolution Imaging Spectroradiometer(MODIS), the Sea-Viewing Wide Field-of-View Sensor(Sea Wi FS), and the Advanced Land Imager(ALI) on board three satellites, respectively. The mean difference between MODIS and Sea Wi FS is less than 3.14%, and the difference between MODIS and ALI is less than 4.75%. These results indicate that the proposed cross-calibration method not only compensates for the RSR mismatches but also reduces the differences in lunar observation geometry. Thus,radiance calibration of any satellite instrument can be validated with a reference instrument bridged by the moon. | Lu ZHANG Peng ZHANG Xiuqing HU Lin CHEN Min MIN Na XU Ronghua WU | 2019 | Journal of Meteorological Research2019，33，5： | 1 |
| 18 | The generalized difference methods for differential equations显示文摘 | Ronghua Li Zhongying Chen Wei Wu | 2000 | Numerial analysis of finite volume method Marcel Dekker New York2000，2000，： | 1 |
| 19 | Development of a smart mobile farming service system 显示文摘 | Lihua Zheng Minzan Li Caicong Wu Haijian Ye Ronghua Ji Xiaolei Deng Yanshuang Che Cheng Fu Wei Guo | 2010 | Mathematical and Computer Modelling2010，543，： | 1 |
| 20 | Solving partial differential equation by using multiquadric quasi-interpolation 显示文摘 | Chen Ronghua Wu Zongmin | 2007 | Applied Mathematics and Computation2007，186，2： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员