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| 1 | Lymphopenia predicts disease severity of COVID-19:a descriptive and predictive study显示文摘Dear Editor,An outbreak of an unknown infectious pneumonia has recently occurred in Wuhan,China.1 The pathogen of the disease was quickly identified as a novel coronavirus(SARS-CoV-2,severe acute respiratory syndrome coronavirus 2),and the disease was named coronavirus disease-19(COVID-19).2 The virus has so far caused 78,959 confirmed cases and 2791 deaths in China according to the reports of government.COVID-19 has been spreading in many countries such as Japan,Korea,Singapore,Iran,and Italia. | Li Tan Qi Wang Duanyang Zhang Jinya Ding Qianchuan Huang Yi-Quan Tang Qiongshu Wang Hongming Miao | 2020 | Signal Transduction and Targeted Therapy2020，5，1： | 4 |
| 2 | Novel P22-monoclonal antibody based blocking ELISA for the detection of African swine fever virus antibodies in serum显示文摘African swine fever(ASF)is a highly infectious,transboundary viral disease of domestic and wild pigs,and is currently the most serious threat to world swine production,resulting in significant economic loss.In the absence of vaccines and treatments,the control of the disease entirely depends on accurate and early diagnosis accompanied by the culling of infected pigs.Thus,a highly specific and sensitive diagnostic assay is required during an outbreak and surveillance of the disease.In this study,a highly sensitive,specific,rapid and repeatable P22-monoclonal antibody-based blocking enzyme-linked immunosorbent assay(bELISA)assay was developed for the detection of antibodies against genotype I and II African swine fever viruses(ASFVs).A total of 806 pig serum samples were tested to evaluate the performance of the diagnostic assay.To determine the PI(percent Inhibition)cut-off value,receiver-operating characteristic(ROC)analysis was applied.According to the ROC analysis of the data,98.10%specificity and 100%sensitivity were recorded when the threshold cut-off value of PI was established at 47%.In addition,the assay was able to detect ASFV antibodies as early as 9 days post-infection when serum samples from experimentally infected pigs were used.Taking all together,the results of the present study indicated that the P22-mAb based bELISA assay can be used for rapid and accurate detection of antibodies against ASFV,which could play a valuable role in the containment and prevention of ASFV as an alternative to other serological diagnostic methods.Also,this study will assist researchers to further investigate the immunogenic importance of P22 protein in ASFV infection. | Ghebremedhin Tsegay Weldu Tesfagaber Yuanmao Zhu Xijun He Wan Wang Zhenjiang Zhang Encheng Sun Jinya Zhang Yuntao Guan Fang Li Renqiang Liu Zhigao Bu Dongming Zhao | 2022 | Biosafety and Health2022，4，4： | 2 |
| 3 | Testing final closure time of the Paleo-Asian Ocean along the Solonker suture by a transition of compressional and extensional setting显示文摘The giant Central Asian Orogenic Belt is an extensive accretionary orogen,of which the Solonker suture,as a major regional suture,coincides closely with an early Permian paleobiogeographical boundary.This suture is considered to mark the location of the final closure of the Paleo-Asian Ocean between the North China Craton and the Mongolian Terrane.Although the closure time of the Paleo-Asian Ocean along the Solonker suture has generally been regarded as Late Permian-Early Triassic,uncertainty remains because of a lack of typical collisionrelated features(e.g.,high-grade regional metamorphism and well-developed fold-thrust structures)and a scarcity of outcrops.The present study reports Early Permian foliated gabbros and dikes(288-275 Ma)and Middle-Late Permian undeformed layered gabbros,strongly peraluminous granites,and I-type granites(265-254 Ma)in the Xinhure area along the northern margin of the North China Craton.The Early Permian foliated intrusions have a subduction-related geochemical signature and were derived from partial melting of lithospheric mantle modified by subduction-related melts or fluids at the active margin of the North China Craton.In contrast,the Late Permian undeformed layered gabbros and strongly peraluminous granites were derived from partial melting of lithospheric mantle and middle-upper crust,respectively,triggered by asthenospheric upwelling.Therefore,a transition from an end-compressional to an extensional environment according to a transition from collision termination to postcollision of the North China Craton and Mongolian Terrane may have occurred between 275 Ma and 262 Ma.This time span can be considered as the final closure time of the Paleo-Asian Ocean along the Solonker suture. | Haidong Zhang Jianchao Liu Jinkun Yang Jiakun Ge Jinya Wang Zhen Li | 2020 | Geoscience Frontiers2020，11，6： | 2 |
| 4 | Multi-objec-tive shape optimization of helico-axial multiphase pumpimpeller based on NSGA-II and ANN 显示文摘 | Zhang Jinya Zhu Hongwu Li Yan | 2011 | Energy Con-version and Management2011，52，1： | 1 |
| 5 | Multi-objective shape optimization of helico-axial multiphase pump impeller based on NSGA-II and ANN显示文摘 | Zhang Jinya Zhu Hongwu Yang Chun | 2011 | Energy Conversion and Management2011，52，1： | 1 |
| 6 | A Numerical Study of Flow Field and Oil Water Separation in Vertical Deadlegs显示文摘 | Kuang Ding Hongwu Zhu Jinya Zhang | 2012 | Applied Mechanics and Materials2012，，： | 1 |
| 7 | Multi-objective shape optimization of helico-axial multiphase pump impeller based on NSGA-II and ANN显示文摘 | Jinya Zhang Hongwu Zhu Chun Yang Yan Li Huan Wei | 2010 | Energy Conversion and Management2010，，1： | 1 |
| 8 | Multi-objective shape optimization of helicoaxial multiphase pump impeller based on NSGA Ⅱ and ANN显示文摘 | ZHANG Jinya ZHU Hongwu YANG Chun | 2011 | Energy Conversion and Management2011，52，1： | 1 |
| 9 | Taking the pulse of subsea trees design towards deepwater application显示文摘 | Ding Kuang Zhu Hongwu Zhang Jinya et aI | 2011 | Ad- vanced Materials Research2011，2，： | 1 |
| 10 | Design and characterization of miniature piezoelectric generators with low resonant frequency 显示文摘 | Ziping Cao Jinya Zhang and Hiroki Kuwano | 2012 | Sensors and Actuators A: Physical2012，179，： | 1 |
| 11 | Efficient synthesis of cyclic carbonates under atmospheric CO_(2) by DMAP-based ionic liquids: the difference of inert hydrogen atom and active hydrogen atom in cation显示文摘The coupling reaction of carbon dioxide(CO_(2)) and epoxides is one of the most efficient pathways to achieve the carbon balance.However,to accomplish it under the mild conditions,especially under the atmospheric pressure,is still a perplexing problem.Three novel ionic liquids(ILs),[DMAPBrPC][TMGH],[DMAPBrPC][DBUH],and[DMAPBrPC][BTMA],are designed and synthesized.All of them display the excellent catalytic activity for the title reaction achieving the yield over 96.6% under the atmospheric CO_(2) pressure at 60℃.Interestingly,[DMAPBrPC][BTMA]with the inert hydrogen atom in cation exhibits the superior catalytic activity as compared to other two ILs with the protic hydrogen atom in cation along with the same anion.The active hydrogen atom in[DMAPBrPC][TMGH]and[DMAPBrPC][DBUH]would impede the–COO^(-)group to absorb CO 2,which is an unfavorable item for the reaction.Moreover,the strong hydrogen bond in[DMAPBrPC][TMGH]and[DMAPBrPC][DBUH]would lessen the nucleophilic ability of Br^(-) anion resulting in the inferior catalytic performance,which is further confirmed by the density functional theory(DFT)calculations.The cation without the active hydrogen atom could also be employed to design the ILs with the excellent catalytic feature when it is combined with the suitable anion. | Zhengkun Zhang Jinya Li Guanyao Yu Chao Zeng Menglong Wang Susu Huang Li Wang Jinglai Zhang | 2023 | Green Chemical Engineering2023，4，3： | 0 |
| 12 | Correction:Lymphopenia predicts disease severity of COVID-19:a descriptive and predictive study显示文摘Correction to:Signal Transduction and Targeted Therapy http://gffzzd3cc09b8251d45dfs5pf05qn65nuw6cnf.ffgz.tsg.suse.edu.cn/10.1038/s41392-020-0148-4,published online 27 March 2020 Since the publication of this article,1 we noticed a minor mistake in the reference that needs to be corrected. | Li Tan Qi Wang Duanyang Zhang Jinya Ding Qianchuan Huang Yi-Quan Tang Qiongshu Wang d Hongming Miao | 2020 | Signal Transduction and Targeted Therapy2020，5，1： | 0 |
| 13 | Consecutive Monitoring of Interleukin-6 Is Needed for COVID-19 Patients显示文摘Dear Editor,The world is facing an immense challenge in the fight against coronavirus disease 2019(COVID-19),which is caused by severe acute respiratory syndrome coronavirus 2(SARS-Co V-2)(Gorbalenya et al.2020).To date,tens of millions of people worldwide have been infected with SARS-Co V-2,and more than a million have died,and the situation continues. | Xiaohua Chen Juan Zhou Chen Chen Baidong Hou Ashaq Ali Feng Li Zhaolin Hua Yingtao Wu Qin Yang Min Chen Rong Zhang Qianchuan Huang Jinya Ding Xian-En Zhang Dong Men | 2021 | Virologica Sinica2021，36，5： | 0 |
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