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| 1 | Stenting for symptomatic intracranial arterial stenosis in China:1-year outcome of a multicentre registry study显示文摘background and purpose A multicentre prospective registry study of individually tailored stenting for a patient with symptomatic intracranial atherosclerotic stenosis(ICAS)combined with poor collaterals in China showed that the short-term safety and efficacy of stenting was acceptable.However,it remained uncertain whether the low event rate could be of a long term.We reported the 1-year outcome of this registry study to evaluate the long-term efficacy of individually tailored stenting for patients with severe symptomatic ICAS combined with poor collaterals.Methods Patients with symptomatic ICAS caused by 70%-99% stenosis located at the intracranial internal carotid,middle cerebral,intracranial vertebral or basilar arteries combined with poor collaterals were enrolled.Balloon-mounted stent or balloon plus self-expanding stent were selected based on the ease of vascular access and lesion morphology determined by the operators.The primary outcome was the rate of 30-day stroke,transient ischaemic attack and death,and 12-month ischaemic stroke within the same vascular territory,haemorrhagic stroke and vascular death after stenting.results From September 2013 to January 2015,300 patients(ages 58.3±9.78 years)were recruited.Among them,159 patients were treated with balloon-mounted stent and 141 with balloon plus self-expanding stent.During the 1-year follow-up,25 patients had a primary end point event.The probability of primary outcome at 1 year was 8.1%(95% CI 5.3% to 11.7%).In 76 patients with digital subtraction angiography follow-up,27.6%(21/76)had re-stenosis≥50% and 18.4%(14/76)had re-stenosis≥70%.No baseline characteristic was associated with the primary outcome.Conclusion The event rate remains low over 1 year of individually tailored stenting for patients with severe symptomatic ICAS combined with poor collaterals.Further randomised trial of comparing individually tailored stenting with best medical therapy is needed. | Ning Ma Yong Zhang Jie Shuai Changchun Jiang Qiyi Zhu Kangning Chen Li Liu Baomin Li Xiangqun Shi Lianbo Gao Yajie Liu Feng Wang Yongli Li Tieyan Liu Hongbo Zheng Dapeng Mo Feng Gao Yilong Wang Yongjun Wang Lei Feng Zhongrong Miao | 2018 | Stroke & Vascular Neurology2018，3，3： | 29 |
| 2 | Relationship between genetic polymorphism of cytochrome P450IIE1 and fatty liver显示文摘AIM: To study the correlation between genetic polymorphism of cytochrome P450IIE1 (CYPIIE1) and fatty liver.METHODS: Peripheral blood mononuclear cells were collected in 56 patients with fatty liver, 26 patients without fatty liver and 20 normal controls. Then PCR-RFLP was used to analyze genetic polymorphism of CYPIIE1 in monocytes on the region of Pst I and Rsa I.RESULTS: The frequency of homozygotic C1 gene in patients with alcoholic fatty liver (28.6 %), obese fatty liver (38.5 %), or diabetic fatty liver (33.3 %) was significantly lower than that of the corresponding patients without fatty liver (100 %, 100 % and 80 % respectively), while the frequency of C2 genes, including C1/C2 and C2/C2, was significantly higher (71.4 %/0 %, 61.5 %/0 %, and 66.7 %/20 %) (P<0.01). The frequency distribution of the above genes of non-fatty liver patients (100 %/0, 100 %/0, and 80 %/20 %) was not significantly different from that of the normal controls (85 %/15 %) (P>0.05).CONCLUSION: The genetic polymorphism of CYPIIE1 on the position of Pst I and Rsa I is related to the susceptibility of fatty liver. Besides, C2 gene may play a key role in the pathogenesis of fatty liver. | Yun-Feng Piao Jing-Tao Li Yang Shi, Department of Gastroenterology, First Hospital, Jilin University, Changchun 130021, Jilin Province, China | 2003 | World Journal of Gastroenterology2003，9，11： | 12 |
| 3 | Inhibitory effect of all-trans retinoic acid on human hepatocellular carcinoma cell proliferation显示文摘AIM: To study the inhibitory effect of all-trans retinoic acid on human hepatocellular carcinoma cell line SMMC-7721and to explore the mechanism of its effect.METHODS: SMMC-7721 cells were divided into two groups, one treated with all-trans retinoic acid (ATRA) for 5 days and the other as a control group. Light microscope and electron microscope were used to observe the morphological changes. Telomerase activity was analyzed with silver-stained telomere repeated assay protocal (TRAP). Expression of Caspase-3 was demonstrated with western blot.RESULTS: ATRA-treated cells showed differentiation features including small and pyknotic nuclei, densely stained chromatin and fewer microvilli. Besides, ATRA could inhibit the activity of telomerase, promote the expression of Caspase-3 and its activation.CONCLUSION: Telomerase activity and Caspase-3expression are changed in human hepatocellular carcinoma cell line SMMC-7721 treated with all-trans retinioc acid.The inhibition of telomerase activity and the activation of Caspase-3 may be the key steps through which ATRA inhibits the proliferation of SMMC-7721 cell line. | Yun-Feng Piao Yang Shi Pu-Jun Gao Department of Gastroenterology,the First Hospital of Jilin University,Changchun,130021,Jilin Province,China | 2003 | World Journal of Gastroenterology2003，9，9： | 9 |
| 4 | Spectral element analysis on the characteristics of seismic wave propagation triggered by Wenchuan M_s8.0 earthquake显示文摘The 2008 Wenchuan earthquake occurred in an active earthquake zone, i.e., Longmenshan tectonic zone. Seismic waves triggered by this earthquake can be used to explore the characteristics of the fault rupture process and the hierarchical structure of the Earth's interior. We employ spectral element method incorporated with large-scale parallel computing technology, to investigate the characteristics of seismic wave propagation excited by Wenchuan earthquake. We calculate synthetic seismograms with one-point source model and three-point source model respectively. The AK135 model is employed as a prototype of our numerical global Earth model. The Earth's ellipticity, Earth’s medium attenuation, and topography data are taken into consideration. These wave propagation processes are simulated by solving three-dimensional elastic wave governing equations. Three-dimensional visualization of our numerical results displays the profile of the seismic wave propagation. The three-point source, which is proposed from the latest investigations through field observation and reverse estimation, can better demonstrate the spatial and temporal characteristics of the source rupture process than the one-point source. We take comparison of synthetic seismograms with observational data recorded at 16 observatory stations. Primary results show that the synthetic seismograms calculated from three-point source agree well with the observations. This can further reveal that the source rupture process of Wenchuan earthquake is a multi-rupture process, which is composed by at least three or more stages of rupture processes. | YAN ZhenZhen ZHANG Huai YANG ChangChun SHI YaoLin | 2009 | Science China Earth Sciences2009，52，6： | 9 |
| 5 | Chaotic Phenomena Produced by the Spherical Vortices in the Beltrami Flows显示文摘We find a special type of Beltrami flows which has chaotic trajectories confined within a sphere or between two concentric spherical shells.We also find there exists the structure of chaotic manifold made from double-torus in some special cases. | SHI Changchun HUANG Yongnian ZHU Zhaoxuan SU Weidong DONG Yufei | 1992 | Chinese Physics Letters1992，9，10： | 5 |
| 6 | Notch signaling:Its essential roles in bone and craniofacial development显示文摘Notch is a cellecell signaling pathway that is involved in a host of activities including development,oncogenesis,skeletal homeostasis,and much more.More specifically,recent research has demonstrated the importance of Notch signaling in osteogenic differentiation,bone healing,and in the development of the skeleton.The craniofacial skeleton is complex and understanding its development has remained an important focus in biology.In this review we briefly summarize what recent research has revealed about Notch signaling and the current understanding of how the skeleton,skull,and face develop.We then discuss the crucial role that Notch plays in both craniofacial development and the skeletal system,and what importance it may play in the future. | Mikhail Pakvasa Pranav Haravu Michael Boachie-Mensah Alonzo Jones Elam Coalson Junyi Liao Zongyue Zeng Di Wu Kevin Qin Xiaoxing Wu Huaxiu Luo Jing Zhang Meng Zhang Fang He Yukun Mao Yongtao Zhang Changchun Niu Meng Wu Xia Zhao Hao Wang Linjuan Huang Deyao Shi Qing Liu Na Ni Kai Fu Michael J.Lee Jennifer Moriatis Wolf Aravind Athiviraham Sherwin S.Ho Tong-Chuan He Kelly Hynes Jason Strelzow Mostafa El Dafrawy Russell R.Reid | 2021 | Genes & Diseases2021，8，1： | 4 |
| 7 | Staged angioplasty versus regular carotid artery stenting in patients with carotid artery stenosis at high risk of hyperperfusion:a randomised clinical trial显示文摘Background and purpose Hyperperfusion(HP)is a devastating complication associated with carotid artery stenting(CAS)or endarterectomy.The efficacy and safety of staged angioplasty(SAP)in patients with CAS at high risk of HP remains unclear.We sought to determine whether SAP is superior to regular CAS in patients with high risk of HP.Methods A randomised,multicentre open-label clinical trial with blinded outcome assessment(STEP)was conducted.Patients with severe carotid stenosis at high risk of HP were randomly assigned(1:1)to the SAP or regular CAS group.The primary endpoint was hyperperfusion syndrome(HPS)and intracerebral haemorrhage(ICH)within 30 days after the procedure.Results From November 2014 to January 2017,a total of 64 patients were enrolled in 11 centres.33 patients were allocated to the SAP group and 31 to the regular CAS group.At 30 days,the rate of primary endpoint was 0.0%(0/33)in the SAP group and 9.7%(3/31)in the regular CAS group(absolute risk reduction(ARR),9.7%;95%CI−20.1% to 0.7%;p=0.11).As one of the secondary endpoints,the incidence of HP phenomenon(HPP)was lower in the SAP group than the regular CAS group(0.0%vs 22.6%,ARR,−22.6%;95% CI−36.8%to−10.2%;p=0.04).Conclusion The rate of HPS and ICH was not significantly lower in SAP group;the extended secondary endpoint of HPP,however,significantly reduced,which suggested that SAP may be a safe and effective carotid revascularisation procedure to prevent HP. | Dapeng Mo Baixue Jia Huaizhang Shi Yaxuan Sun Qingan Liu Chengzhe Fan Jianping Deng Jinglin Yuan Wei Wu Changchun Jiang Guilian Zhang Hanjun Du Ning Ma Feng Gao Xuan Sun Ligang Song Lian Liu Guangge Peng Yongjun Wang Yilong Wang Zhongrong Miao the STEP Study Group | 2021 | Stroke & Vascular Neurology2021，6，1： | 3 |
| 8 | Luminescent properties of Ba_3(PO_4)_2:Eu,Tb phosphors显示文摘Luminescence of europium (Ⅲ),europium(Ⅱ) and terbium(Ⅲ) has been observed in Bas(PO4)2:Eu,Tb phosphors which are synthesized in air atmosphere.The valence state of europium is influenced by amount of terbium.It is notable that the relative intensity of the emission spectra peaks corresponding to Eu2+ is increased if the amount of Tb3+ is increased.These phenomena can be explained by an electron transfer mechanism.We predict a new kind of two-rare-earth codoped trichromatic phosphors in Ba3(PO4)2 matrix. | GAO,Yong SHI,Chun-ShanLaboratory of Rare Earth Chemistry and Physics,Changchun Institute of Applied Chemistry,Chinese Academy of Sciences,Changchun,Jilin 130022,China | 1996 | Chinese Journal of Chemistry1996，14，5： | 3 |
| 9 | On nonparametric change point estimator based on empirical characteristic functions显示文摘We propose a nonparametric change point estimator in the distributions of a sequence of independent observations in terms of the test statistics given by Huˇskov′a and Meintanis(2006) that are based on weighted empirical characteristic functions. The weight function ω(t; a) under consideration includes the two weight functions from Huˇskov′a and Meintanis(2006) plus the weight function used by Matteson and James(2014),where a is a tuning parameter. Under the local alternative hypothesis, we establish the consistency, convergence rate, and asymptotic distribution of this change point estimator which is the maxima of a two-side Brownian motion with a drift. Since the performance of the change point estimator depends on a in use, we thus propose an algorithm for choosing an appropriate value of a, denoted by a_s which is also justified. Our simulation study shows that the change point estimate obtained by using a_s has a satisfactory performance. We also apply our method to a real dataset. | TAN ChangChun SHI XiaoPing SUN XiaoYing WU YueHua | 2016 | Science China Mathematics2016，59，12： | 3 |
| 10 | False anomaly recognition with horizontal differential field lines method in high-density electrical technique and its application in Xinlei Quarry,Jiuquan显示文摘As an important geophysical tool,high density electrical technique infers the underground geological structures by processing and inverting the apparent resistivity data.Currently,the false anomalies have been frequently occurred in the graph of apparent resistivity pseudo-section or inverted geoelectrical section obtained from high-density electrical technique,and are difficult to remove.In this study,the authors explain the mechanism of the false anomalies and put forward the horizontal differential field method to identify the false anomalies.Based on the analysis of modeling results,this method is applied in the surveying data in Xinlei Quarry of Jiuquan,and the results confirm the effectiveness of the horizontal differential field method. | LIU Lijia ZHU Shi CAO Xiaoyue BEN Fang YIN Changchun | 2015 | Global Geology2015，18，2： | 2 |
| 11 | Physical Diffusion and Electron-transfer Dynamics of Electroactive Solutes in Polymer Electrolytes Ⅲ. Effect of the Polymer Solvents显示文摘The diffusion coefficients(Dapp) and the heterogeneous electron transfer rate constants(ks)for ferrocene in several polymer solvents were determined by using steady-stae voltammetry. Thetemperature dependence of the two parameters indicates Arrhenius behavior. The polymer solventeffects on diffusion and electron transfer dynamics of ferrocene were | Li Ming DING Zhong SHI Hua Fang ZHOU and Shao Jun DONG(Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022) | 1997 | Chinese Chemical Letters1997，8，10： | 2 |
| 12 | Luminescent properties of Eu and Tb in SrB_(6)O_(10) matrix显示文摘MOST rare earth ions are inclined to exist in abnormal valency, and the properties of rare earth correspond to the valence state of rare earth closely Both europium and terbium have abnormal valence state. Eu3+ and Tb3+ ions are a couple of conjugate rare earth ions; they are both important activated ions. The present note reports the luminescent properties of SrB6O10 xEu, yTb phosphors which are synthesized in air atmosphere. Eu3+, Eu2+ and Tb3+ ions can coexist in SrB6O10: xEu, yTb phosphors, and the emission intensity of europium(Ⅱ) is increased if the concentration of terbium(Ⅲ) is increased in SrB6O10: 0.006Eu3+, yTb3+ | GAO Yong, SHI Chunshan and LI DechengLaboratory of Rare Earth Chemistry and Physics, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences. Changchun 130022, China | 1997 | Chinese Science Bulletin1997，42，5： | 2 |
| 13 | Design and Fabrication of Polymer Arrayed Waveguide Grating显示文摘In this paper, based on the principle of Arrayed Waveguide Grating (AWG) theory, some important parameters are optimized for polymer AWG around the central wavelength of 1.55? μm with the wavelength spacing of 1.6? nm . Then, a 9×9 polymer AWG is designed and the fabricating process are described. The cladding material is poly methyl methacrylate co glyciclyl methacrylate (PMMA GMA) and the core material is the mixture of PMMA GMA and bis phonel A epoxy. In order to obtain a better shape of the waveguide after the Reactive Ion Etching (RIE) using oxygen, an aluminum mask is used on polymer instead of conventional photoresist as mask in the fabrication process. The measuring results indicate that the fabricated optical waveguide achieves single mode transmission. | ZHANG Da ming, WANG Fei, ZHANG Zhen guo, ZHAO Yu, YI Mao bin, LIU Shi yong (State Key Laboratory of Integrated Optoelectronics, Jilin University, Changchun 130023, P.R.China) | 2003 | The Journal of China Universities of Posts and Telecommunications2003，10，2： | 2 |
| 14 | Oxygen vacancies enriched nickel cobalt based nanoflower cathodes: Mechanism and application of the enhanced energy storage显示文摘The rational design of oxygen vacancies and electronic microstructures of electrode materials for energy storage devices still remains a challenge. Herein, we synthesize nickel cobalt-based oxides nanoflower arrays assembled with nanowires grown on Ni foam via the hydrothermal process followed annealing process in air and argon atmospheres respectively. It is found that the annealing atmosphere has a vital influence on the oxygen vacancies and electronic microstructures of resulting NiCo_(2)O_(4) (NCO-Air) and CoNiO_(2) (NCO-Ar) products, which NCO-Ar has more oxygen vacancies and larger specific surface area of 163.48 m^(2)/g. The density functional theory calculation reveals that more oxygen vacancies can provide more electrons to adsorb –OH free anions resulting in superior electrochemical energy storage performance. Therefore, the assembled asymmetric supercapacitor of NCO-Ar//active carbon delivers an excellent energy density of 112.52 Wh/kg at a power density of 558.73 W/kg and the fabricated NCO-Ar//Zn battery presents the specific capacity of 180.20 mAh/g and energy density of 308.14 Wh/kg. The experimental measurement and theoretical calculation not only provide a facile strategy to construct flower-like mesoporous architectures with massive oxygen vacancies, but also demonstrate that NCO-Ar is an ideal electrode material for the next generation of energy storage devices. | Jiahui Ye Xingwu Zhai Long Chen Wen Guo Tiantian Gu Yulin Shi Juan Hou Fei Han Yi Liu Changchun Fan Gang Wang Shanglong Peng Xuhong Guo | 2021 | Journal of Energy Chemistry2021，30，11： | 2 |
| 15 | Source apportionment of polycyclic aromatic hydrocarbons(PAHs) in a sediment core from Lake Dagze Co, Tibetan Plateau, China: Comparison of three receptor models显示文摘Receptor models are a useful tool for identifying sources of polycyclic aromatic hydrocarbons(PAHs) in multiple environmental media. In this study, three different receptor models(including the principal component analysis-multiple linear regression(PCA-MLR), positive matrix factorization(PMF), and Unmix models) were used to apportion the sources of 16 priority PAHs in a sediment core of Lake Dagze Co. The ΣPAHs(sum of all 16 measured PAHs) concentrations ranged from 51.89 to 132.82 ng/g with an average of 80.39 ng/g. TheΣ PAHs were dominated by 2-3 ring PAHs, accounting for 80.12% on average, thereby indicating that they mainly originated from biomass and coal combustion and/or from long-range atmospheric transportation. The three models produced consistent source apportionment results. The greatest contributor to ΣPAHs was biomass combustion, followed by coal combustion, vehicle emissions, and petrogenic sources. Moreover, the temporal variation of the common sources was well-correlated among models. The multi-method comparison and evaluation results showed that all three models were useful tools for source apportionment of PAHs, with the PMF model providing better results than the PCA-MLR and Unmix models. The temporal trends of factor contributions were verified by PAHs with different ring numbers. Significant correlations were found between the simulated concentrations of each source factor and the PAHs with different ring numbers(P<0.01), except for the petrogenic source identified by the Unmix model(P>0.05). This study can provide useful information for further investigation of source apportionment of PAHs in the sediment cores. | Yixin Bai Kunlin Shi Heyu Yu Nana Shang Weiyue Hao Chuan Wang Tao Huang Hao Yang Changchun Huang | 2022 | Journal of Environmental Sciences2022，34，11： | 2 |
| 16 | In vitro inhibition of CSFV replication by retroviral vector-mediated RNA interference显示文摘 | Jiangnan Li Huancheng Guo Zixue Shi Changchun Tu | 2010 | Journal of Virological Methods2010，，2： | 1 |
| 17 | Synthesis and Characterization of Liquid Crystal with Lower Temperature of Phase Change of meso-tetra-(4-n-lauroyloxyphenyl)porphyrin显示文摘The synthesis and characterization of meso-tetra (4-n-lauroyloxy phenyl) porphyrinwith long ester chains are reported. The domains of stability and the structure of the liquidcrystalline phases are determined by optical microscopy and differential scanning calorimerials(DSC). | Wei LIU Tong Shun SHI(1 Department of chemistry, The Forth Military Medical University, Xian 7100322 Department of chemistry, Jilin University. Changchun 130023) | 1999 | Chinese Chemical Letters1999，10，9： | 1 |
| 18 | Effect of the capsule on deformation and densification behavior of nickel-based superalloy compact during hot isostatic pressing显示文摘The Shima yield criterion used in finite element analysis for nickel-based superalloy powder compact during hot isostatic pressing(HIP) was modified through uniaxial compression experiments. The influence of cylindrical capsule characteristics on FGH4096M superalloy powder compact deformation and densification behavior during HIP was investigated through simulations and experiments. Results revealed the simulation shrinkage prediction fitted well with the experimental shrinkage including a maximum shrinkage error of 1.5%. It was shown that the axial shrinkage was 1.7% higher than radial shrinkage for a cylindrical capsule with the size of ∮50 mm × 100 mm due to the force arm difference along the axial and radial direction of the capsule. The stress deviated from the isostatic state in the capsule led to the uneven shrinkage and non-uniform densification of the powder compact. The ratio of the maximum radial displacement to axial displacement increased from0.47 to 0.75 with the capsule thickness increasing from 2 to 4 mm. The pressure transmission is related to the capsule thickness, the capsule material performance, and physical parameters in the HIP process. | Lebiao Yang Xiaona Ren Chao Cai Pengju Xue MIrfan Hussain Yusheng Shi Changchun Ge | 2023 | International Journal of Minerals,Metallurgy and Materials2023，30，1： | 1 |
| 19 | Hydrothermal Synthesis and Crystal Structure of Inorganic-organic Hybrid Compound [H_3NC_2H_4NH_2]VOPO_4显示文摘An inorganic-organic hybrid compound, [H3NC2H4NH2]VOPO4 was synthesized by meansof the hydrothermal method. It was crystallized in a monoclinic system, a space group P21/c,with the crystal cell parameters: a=0. 922 85(11) nm, b=0. 729 94(9) nm, c=0. 984 95(11)nm, β=101. 280(3)°, V=0. 650 67(13) nm3, Mr=223.02 g/mol, Dc=2. 277 g/cm3, Z=4,R= 0. 031 5, ωR= 0. 086 5, GOF = 1. 085. The VO5N octahedra chains are corner-linked byPO4 tetrahedra; the VOsN octahedra are all trans-linked with V-O bonds being alternately short and long. The monoprotonated ethylenediamine was intercalated between the layers with one end coordinating to V and the other end as an H-bond donor interacting with a terminal O atom of PO4 from a neighboring sheet. The elementary analysis, infrared spectrum characters and thermal stability were also given. | ZHANG Dong, SHI Zhan and FENG Shou-hua~(**) (National Key Laboratory of Inorganic Synthesis & Preparative Chemistry, Department of Chemistry, Jilin University, Changchun 130023, P. R. China) To whom correspondence should be addressed. | 2001 | Chemical Research in Chinese Universities2001，17，3： | 1 |
| 20 | CD14 Contributes to Warm Hepatic Ischemia-Reperfusion Injury in Mice显示文摘 | Changchun Cai Xiaolian Shi Sebastian Korff Jinxiang Zhang Patricia A. Loughran Xiangcai Ruan Yong Zhang Li Liu Timothy R. Billiar | 2013 | Shock2013，，2： | 1 |
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