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| 1 | Initial study of biexponential model of intravoxel incoherent motion magnetic resonance imaging in evaluation of the liver fibrosis显示文摘 | Chen Cuiyun Wang Bin Shi Dapeng Fu Fangfang Zhang Jiliang Wen Zejun Zhu Shaocheng Xu Junling Lin Qing Li Jing Dou Shewei | 2014 | Chinese Medical Journal2014，，17： | 15 |
| 2 | Epidemic Update and Risk Assessment of 2019 Novel Coronavirus--China, January 28, 2020显示文摘On December 29,2019,the health authorities in Hubei Province and Wuhan City received a report of a cluster of pneumonia cases of unknown etiology from a local hospital,and all four patients were employees of the Wuhan Huanan Seafood Wholesale Market(HN market for short)(1).By January 8,2020,Chinese authorities had identified a new virus 2019 novel coronavirus(2019-nCoV)linked with the outbreak of disease,which has been named novel coronavirusinfected pneumonia(NCIP)(2).On 15 January,the National Health Commission(NHC)issued guidelines for the diagnosis,treatment,prevention,and control of NCIP.These guidelines directed case monitoring,reporting,diagnosis,treatment,management,close contact management,and laboratory testing. | Wenxiao Tu Houlin Tang Fangfang Chen Yinong Wei Tingling Xu Kaiju Liao Nijian Xiang Guoqing Shi Qun Li Zijian Feng | 2020 | China CDC weekly2020，2，6： | 15 |
| 3 | Application of cylindrical linear phased array in casing borehole显示文摘一个超声的分阶段执行的数组( UPA )变换器在听觉的 logging.First 为地上凿穿成像和 casing 检查被介绍,一个圆柱的线性分阶段执行的数组( CLPA )它由压电的元素的数字组成一致地在柱体的表面上散布了,被设计并且在电的系统的控制下面用元素的不同的组播送并且收到声学的波浪的 fabricated.By , CLPA 罐头(s)地上凿穿的所有区域能动态地围并且 rapidly.Then | SHI Fangfang WU Xianmei KE Yijing ZHANG Bixing | 2010 | Chinese Journal of Acoustics2010，29，1： | 10 |
| 4 | Effect of Sc and Zr additions on microstructures and corrosion behavior of Al-Cu-Mg-Sc-Zr alloys显示文摘The effects of adding the alloy element Sc to Al alloys on strengthening, recrystallization and modification of the grain microstructure have been investigated. The combination of Sc and Zr alloying not only produces a remarkable synergistic effect of inhibition of recrystallization and refinement of grain size but also substantially reduce the amount of high-cost additional Sc. In this work, the microstructures and corrosion behavior of a new type of Al-Cu-Mg-Sc-Zr alloy with Sc/Zr ratio of 1/2 were investigated.The experimental results showed that the Sc and Zr additions to Al-Cu-Mg alloy could strongly inhibit recrystallization, refine grain size, impede the segregation of Cu element along the grain boundary and increase the spacing of grain boundary precipitates. In addition, adding Sc and Zr to Al-Cu-Mg alloy effectively restricts the corrosion mechanism conversion associated with Al2 Cu Mg particles, which resulted in the change of the cross-section morphology of inter-granular corrosion from an undercutting to an elliptical shape. The susceptibility to inter-granular corrosion was significantly decreased with increasing Sc and Zr additions to the Al-Cu-Mg alloy. The relationships between microstructures evolution and inter-granular corrosion mechanism of Al-Cu-Mg-Sc-Zr alloys were also discussed. | Fangfang Sun Guiru Liu Nash Qunying Li Enzuo Liu Chunnain He Chunsheng Shi Naiqin Zhao | 2017 | Journal of Materials Science & Technology2017，33，9： | 10 |
| 5 | Interval mapping for red/green skin color in Asian pears using a modified QTL-seq method显示文摘Pears with red skin are attractive to consumers and provide additional health benefits.Identification of the gene(s)responsible for skin coloration can benefit cultivar selection and breeding.The use of QTL-seq,a bulked segregant analysis method,can be problematic when heterozygous parents are involved.The present study modified the QTL-seq method by introducing a|Δ(SNP-index)|parameter to improve the accuracy of mapping the red skin trait in a group of highly heterozygous Asian pears.The analyses were based on mixed DNA pools composed of 28 red-skinned and 27 green-skinned pear lines derived from a cross between the‘Mantianhong’and‘Hongxiangsu’red-skinned cultivars.The‘Dangshansuli’cultivar genome was used as reference for sequence alignment.An average single-nucleotide polymorphism(SNP)index was calculated using a sliding window approach(200-kb windows,20-kb increments).Nine scaffolds within the candidate QTL interval were in the fifth linkage group from 111.9 to 177.1 cM.There was a significant linkage between the insertions/deletions and simple sequence repeat markers designed from the candidate intervals and the red/green skin(R/G)locus,which was in a 582.5-kb candidate interval that contained 81 predicted protein-coding gene models and was composed of two subintervals at the bottom of the fifth chromosome.The ZFRI 130-16,In2130-12 and In2130-16 markers located near the R/G locus could potentially be used to identify the red skin trait in Asian pear populations.This study provides new insights into the genetics controlling the red skin phenotype in this fruit. | Huabai Xue Ting Shi Fangfang Wang Huangkai Zhou Jian Yang Long Wang Suke Wang Yanli Su Zhen Zhang Yushan Qiao Xiugen Li | 2017 | Horticulture Research2017，4，1： | 5 |
| 6 | Isolation and phylogenetic study of Rift Valley fever virus from the first imported case to China显示文摘Dear Editor,Rift Valley fever(RVF)is an anthropozoonosis caused by Rift Valley fever virus(RVFV).RVFV belongs to the Phlebovirus genus in the family Bunyaviridae,which is circulating among ruminants.Human infection with RVFV is generally asymptomatic,however,minority of patients develop severe RVF diseases like encephalitis | Yongxia Shi Kui Zheng Xiaobo Li Liqiang Li Shufen Li Jinmin Ma Jun Dai Jingkai Ji Shuai Yuan Haorong Lu Jiandong Li Fangfang Sun Xun Xu Jicheng Huang | 2017 | Virologica Sinica2017，32，3： | 4 |
| 7 | Scalable salt-templated directed synthesis of high-quality MoS_(2) nanosheets powders towards energetic and environmental applications显示文摘Two-dimensional(2D)transition metal dichalcogenides(TMDCs)have emerged as perfect platforms for developing applications in nano-electronics,catalysis,energy storage and environmental-related fields due to their superior properties.However,the low-cost,batch production of high-quality 2D TMDCs remains a huge challenge with the existing synthetic strategies.Herein,we present a scalable chemical vapor deposition(CVD)approach for the batch production of high-quality MoS_(2) nanosheet powders,by using naturally abundant,water-soluble and recyclable NaCl crystal powders as templates.The high-quality MoS_(2) nanosheets powders are achieved by a facile water dissolution-filtration process,by virtue of the excellent dispersibility of the as-grown products in water.The internal mechanism for the scalable synthesis strategy is explored.The applications of the MoS_(2) nanosheets powders are also demonstrated as catalysts or adsorbents in hydrogen evolution reaction(HER)and organic dyes adsorption,respectively.This work should hereby pave ways for the mass production and application of powdery TMDCs in energetic and environmental related fields. | Lijie Zhu Pengfei Yang Yahuan Huan Shuangyuan Pan Zhaoqian Zhang Fangfang Cui Yuping Shi Shaolong Jiang Chunyu Xie Min Hong Jiatian Fu Jingyi Hu Yanfeng Zhang | 2020 | Nano Research2020，13，11： | 4 |
| 8 | A high quality image reconstruction method based on nonconvex decoding显示文摘The article proposes a fast reconstruction algorithm for l0≤p≤1 norm nonconvex model,called Gradient projection nonconvex sparse recovery(GPNSR),which makes a good performance in high-quality image reconstruction.We apply the GPNSR into canonical multiple description coding theory and propose a robust high-quality compressed sensing-based coding method.Combined with iterative weighted technique and fast gradient descent method,the proposed method implicitly implements matrix inverse operations to highly reduce the storage pressure.Also the weighted norm method is taken to optimize the descent steps,which highly increases convergent speed of the algorithm.Taking an image has sparse Fourier representations as an example,the paper presents the detailed image sparse coding and fast reconstruction procedure.By integrating the compressive sensing multi-description coding framework,the simulation demonstrates the superior reconstruction performance of the proposed algorithm.Most importantly,with p close to zero,the reconstruction performance of GPNSR can approximate that of l0 norm optimization result. | ZHAO GuangHui SHEN FangFang WANG ZhengYang WU WeiJia SHI GuangMing LIU DanHua | 2013 | Science China(Information Sciences)2013，56，11： | 3 |
| 9 | Acoustic field analysis of detection and location of targets in layered media by time reversal-reverse time migration mixed method显示文摘Using the time reversal(TR)-reverse time migration(RTM) mixed method, the numerical analysis towards the acoustic field for detection and location of targets in layered media is performed. First the approaches and steps of the numerical analysis and simulation for acoustic field are proposed, then, the acoustic field distribution of single target and multiple targets are further computed by using the approaches of single emission-multiple receiving and multiple emission-multiple receiving. The numerical simulation results indicate that target detection and location can be well realized. By comparison, good results are obtained from the both two approaches, but large time-consuming is observed in way of multiple emission-multiple receiving, and so would be unacceptable. Additionally, the improved way is also proposed for multiple target detection. | GAO Xiang LI Jian SHI Fangfang MA Jun WANG Wen WANG Chenghao | 2017 | Chinese Journal of Acoustics2017，36，4： | 3 |
| 10 | Experimental investigation of the detection and location of a target in layered media by using the TR-RTM mixed method显示文摘Targets in layered media can be detected and located using a time reversal(TR)-reversed-time migration(RTM) mixed method.In this study, this single emission-multiple receiving method is tested experimentally by using two types of layered media and three types of targets. The signal reflected at the interface and the signal scattered by the target are measured by each receiver to obtain the travel time for several transmitter-receiver pairs. Thereafter, the amplitude ratio between the two measured signals is compared with the theoretical amplitude. The RTM process involves the convolution of the forward acoustic beam from the source with the backward acoustic beam from the receiver which adds an appropriate delay determined on the measured travel time data. By using this approach, the acoustic field distribution can be obtained, and the position of the target can be determined.Moreover, the measured positions of the target are compared with the actual position to validate the accuracy of this technique. | Xiang Gao Jian Li Jun Ma JunHong Li FangFang Shi Wen Wang ChengHao Wang | 2019 | Science China(Physics,Mechanics & Astronomy)2019，62，3： | 3 |
| 11 | A compact polarization-integrated long wavelength infrared focal plane array based on In As/GaSb superlattice显示文摘Real-time polarization imaging plays a vital role in target detection,recognition,and tracking in complex scenes.However,large optical crosstalk and the integration technology are difficult problems in the development of polarization-integrated infrared detectors.We demonstrate a monolithic long wavelength infrared(LWIR)In As/Ga Sb superlattice focal plane array(FPA)integrated with the polarizer.To obtain high performance and real-time polarization imaging devices,the parameters of the grating were optimized and the optical crosstalk between adjacent polarization bands was studied.We analyze the light diffraction depending on the distance between the polarizer and photosensitive elements and the coupling between oblique incident light and device.The fabrication process of the antireflective polarizer,the integration technology of the polarizer and the FPA composed of 512×4×3 pixels were explored.Finally,a polarization integrated focal plane array(PI-FPA)was fabricated to detect polarized light with different oscillating directions.The large response extinction ratio of corresponding polarization bands was measured as 50:1,49:1,and 44:1 of 0°,60°,and 120°,respectively. | Jian ZHOU Yi ZHOU Ying SHI Fangfang WANG Zhicheng XU Zhizhong BAI Min HUANG Lulu ZHENG Zhaoming LIANG Yihong ZHU Qingqing XU Yiming SHEN Xiangxiao YING Jianxin CHEN | 2022 | Science China(Information Sciences)2022，65，2： | 2 |
| 12 | Drosophila Myc integrates multiple signaling pathways to regulate intestinal stem cell proliferation during midgut regeneration显示文摘在果蝇成年 midgut 的肠的干细胞(ISC ) 为维持织物动态平衡是必要的,并且他们的增长和区别加快以便为填满遇见需求响应损害的失去的房间。包括 JAK-STAT, EGFR 和河马(Hpo ) 小径的几个发信号小径在导致损坏的 ISC 增长被含有,但是集成这些小径的机制留下了逃犯。这里,我们证明 oncoprotein Myc (dMyc ) 的果蝇相当或相同的事物这些下游地工作表明小径调停他们 ISC 增长上的效果。在先锋房间的 dMyc 表示响应织物损坏被刺激,并且 dMyc 为加速的 ISC 增长和 midgut 新生是必要的。我们证明葡聚糖硫酸盐钠喂引起的那织物损坏经由 Hpo 小径刺激 dMyc 表示,而喂的 bleomycin 通过 JAK-STAT 和 EGFR 小径激活 dMyc。我们提供 dMyc 表示是的证据 transcriptionally 由多重发信号的小径的 upregulated,它响应织物为最佳的 ISC 增长被要求损坏。我们也获得了证据那织物损坏罐头 upregulate dMyc 表情 post-transcriptionally。最后,我们证明 dMyc 表示的基础水平在正常织物动态平衡期间为 ISC 维护,增长和系区别被要求。 | Fangfang Ren Qing Shi Yongbin Chen Alice Jiang Y Tony Ip Huaqi Jiang Jin Jiang | 2013 | Cell Research2013，23，9： | 2 |
| 13 | Response of seasonal vegetation development to climatic variations in eastern central Asia显示文摘 | Fangfang Yu Kevin P Price James Ellis Peijun Shi | 2003 | Remote Sensing of Environment2003，，1： | 2 |
| 14 | Direct access to β-seleno sulfones at room temperature through selenosulfonylation of alkenes显示文摘A new protocol has been developed for the formation of C.Se and C.S bonds by the direct selenosulfonylation of alkenes.This protocol is operationally simplistic, has a wide substrate scope, uses readily available seleno and sulfonyl sources, and is amenable to gram-scale synthesis. This reaction represents a significant addition to the limited number of reactions available for the intermolecular selenide difunctionalization of alkenes and would be useful for the synthesis of sulfur-and selenium-containing molecules. | Kai Sun Yunhe Lv Zuodong Shi Fangfang Fu Chong Zhang Zhiguo Zhang | 2017 | Science China Chemistry2017，60，6： | 1 |
| 15 | Magnetic molecularly imprinted polymer for the detection of rhaponticin in Chinese patent medicines显示文摘 | Chen Fangfang Xie Xiaoyu Shi Yanping | 2012 | Journal of Chromatography A2012，1252，： | 1 |
| 16 | Seven new 3,4-dihydro-furanocoumarin derivatives from Angelica dahurica显示文摘Objective:To study the chemical constituents of the roots of Angelica dahurica,a well-known Chinese herbal medicine named Baizhi in Chinese.Methods:Compounds were separated by various chromatographies,and the structures of new compounds were elucidated based on the analysis of their spectroscopic and spectrometric data(1D,2D NMR,HRESI MS,IR,and UV).The absolute configurations of new compounds were determined by the calculated electronic circular dichroism and chemical derivatization.The inhibitory activities of all isolates against nitric oxide(NO)production were evaluated using lipopolysaccharide-activated RAW 264.7macrophage cells.Results:Seven new 3,4-dihydro-furanocoumarin derivatives(1a/1b,2a/2b,3a/3b,4)together with a known furanocoumarin(5)were isolated from the roots of A.dahurica.The new compounds included three pairs of enantiomers,(4S,2’’R)-angelicadin A(1a)/(4R,2’’S)-angelicadin A(1b),(4S,2’’S)-angelicadin A(2a)/(4R,2’’R)-angelicadin A(2b),and(4S,2’’S)-secoangelicadin A(3a)/(4R,2’’R)-secoangelicadin A(3b),together with(4R,2’’R)-secoangelicadin A methyl ester(4).The known xanthotoxol(5)inhibited the NO production with the half-maximal inhibitory concentration(IC50)value of(32.8±0.8)μmol/L,but all the new compounds showed no inhibitory activities at the concentration of100μmol/L.Conclusion:This is the first report of the discovery of 3,4-dihydro-furanocoumarins from A.dahurica.The results are not only meaningful for the understanding of the chemical constituents of A.dahurica,but also enrich the reservoir of natural products. | Yang Wang Fanyu Shi Zihan Lu Mingliang Zhang Zekun Zhang Fangfang Jia Beibei Zhang Lishan Ouyang Zhixiang Zhu Shepo Shi | 2023 | Chinese Herbal Medicines2023，15，3： | 1 |
| 17 | Ultrahigh Thermoelectric Performance by Electron and Phonon Critical Scattering in Cu2Se1‐xIx显示文摘 | Huili Liu Xun Yuan Ping Lu Xun Shi Fangfang Xu Ying He Yunshan Tang Shengqiang Bai Wenqing Zhang Lidong Chen Yue Lin Lei Shi He Lin Xingyu Gao Xingmin Zhang Hang Chi Ctirad Uher | 2013 | Mater2013，，45： | 1 |
| 18 | An Old Story Retold: Loss of G1 Control Defines A Distinct Genomic Subtype of Esophageal Squamous Cell Carcinoma显示文摘Esophageal squamous cell carcinoma(ESCC) has a high mortality rate. To determine the molecular basis of ESCC development, this study sought to identify characteristic genome-wide alterations in ESCC, including exonic mutations and structural alterations. The clinical implications of these genetic alterations were also analyzed. Exome sequencing and verification were performed for nine pairs of ESCC and the matched blood samples, followed by validation with additional samples using Sanger sequencing. Whole-genome SNP arrays were employed to detect copy number alteration(CNA) and loss of heterozygosity(LOH) in 55 cases, including the nine ESCC samples subjected to exome sequencing. A total of 108 non-synonymous somatic mutations(NSSMs) in102 genes were verified in nine patients. The chromatin modification process was found to be enriched in our gene ontology(GO) analysis. Tumor genomes with TP53 mutations were significantly more unstable than those without TP53 mutations. In terms of the landscape of genomic alterations, deletion of 9p21.3 covering CDKN2A/2B(30.9%), amplification of 11q13.3 covering CCND1(30.9%), and TP53 point mutation(50.9%) occurred in two-thirds of the cases. These results suggest that the deregulation of the G1 phase during the cell cycle is a key event in ESCC.Furthermore, six minimal common regions were found to be significantly altered in ESCC samples and three of them, 9p21.3, 7p11.2, and 3p12.1, were associated with lymph node metastasis. With the high correlation of TP53 mutation and genomic instability in ESCC, the amplification of CCND1, the deletion of CDKN2A/2B, and the somatic mutation of TP53 appear to play pivotal roles via G1 deregulation and therefore helps to classify this cancer into different genomic subtypes.These findings provide clinical significance that could be useful in future molecular diagnoses and therapeutic targeting. | Qiyan Wang Jian Bai Amir Abliz Ying Liu Kenan Gong Jingjing Li Wenjie Shi Yaqi Pan Fangfang Liu Shujuan Lai Haijun Yang Changdong Lu Lixin Zhang Wei Chen Ruiping Xu Hong Cai Yang Ke Changqing Zeng | 2015 | Genomics, Proteomics & Bioinformatics2015，13，4： | 1 |
| 19 | Experimental study on effect of recombinant human growth hormone combined with chemotherapy on stomach neoplasms implanted in nude mice显示文摘Objective: To investigate the effect of different doses of recombined growth hormone (rhGH) on stomach neo- plasms implanted in nude mice, and its efficacy in combining with chemotherapy (flurouracil, 5-FU). Methods: Human stom- ach neoplasms model was established in nude mice. The nude mice were divided into control group, moderate-dose of rhGH group, low-dose rhGH group, 5-FU group, moderate-dose rhGH/5-FU group, and low-dose rhGH/5-FU group. The results of each group were observed after ten days. Results: After therapy, the body mass of rhGH groups was significantly increased compared with control group (P<0.05), the body mass of rhGH/5-FU groups was significantly increased compared with 5-FU group (P<0.05), but it was no significant difference between rhGH/5-FU groups and control group (P>0.05). The average tumor mass and volume of rhGH groups were not significantly increased compared with control group (P>0.05), but they were significantly reduced in 5-FU group and rhGH/5-FU groups (P<0.05). They were no significant difference between rhGH/5- FU groups and 5-FU group (P>0.05). After treatment, the percentages of S, G0/G1 and G2/M phases and proliferation index (PI) were not significantly changed in rhGH groups compared with control group (P>0.05), and the same with rhGH/5-FU groups compared with 5-FU group (P>0.05). The difference caused by dose of rhGH was not significant. Conclusion: rhGH enhances body mass, does not stimulate tumor growth, and has no adverse effects on tumor bearing nude mice. Combined with flurouracil, rhGH does not influence the efficacy of chemotherapy, and has no effect on tumor cell cycle kinetics. | Fangfang Shi Suyi Li | 2007 | The Chinese-German Journal of Clinical Oncology2007，6，1： | 1 |
| 20 | Molecularly imprinted pol- ymer for the specific solid-phase extraction of kirenol from Sieges- beckia pubescens herbal extract显示文摘 | Chen Fangfang Wang Rui Shi Yanping | 2012 | Talanta2012，89，30： | 1 |
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