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| 1 | Long-term outcome and prognostic factors of patients with hilar cholangiocarcinoma显示文摘AIM: To evaluate the long-term outcome and prognostic factors of patients with hilar cholangiocarinoma. METHODS: Ninety-six consecutive patients underwent treatment for malignant hilar bile duct tumors during 1995–2005. Of the 96 patients, 20 were initially treated with surgery (n = 2 R0 / n = 18 R1). In non-operated patients, data analysis was performed retrospectively. RESULTS: Among the 96 patients, 76 were treated with endoscopic transpapillary (ERC, n = 45) and/or percutaneous transhepatic biliary drainage (PTBD, n = 31). The mean survival time of these 76 patients undergoing palliative endoscopic and/or percutaneous drainage was 359 ± 296 d. The mean survival time of patients with initial bilirubin levels > 10 mg/dL was significantly lower (P < 0.001) than patients with bilirubin levels < 10 mg/dL. The mean survival time of patients with Bismuth stage Ⅱ (n = 8), Ⅲ (n = 28) and Ⅳ (n = 40) was 496 ± 300 d, 441 ± 385 d and 274 ± 218 d, respectively. Thus, patients with advanced Bismuth stage showed a reduced mean survival time, but the difference was not significant. The type of biliary drainage had no significant beneficial effect on the mean survival time (ERC vs PTBD, P = 0.806). CONCLUSION: Initial bilirubin level is a significant prognostic factor for survival of patients. In contrast, age, tumor stage according to the Bismuth-Corlette classification, and types of intervention are not significant prognostic parameters for survival. Palliative treatment with endoscopic or percutaneous biliary drainage is still suboptimal, new diagnostic and therapeutic tools need to be evaluated. | Andreas Weber Sonja Landrock Jochen Schneider Manfred Stangl Bruno Neu Peter Born Meinhard Classen Thomas Rsch Roland M Schmid Christian Prinz | 2007 | World Journal of Gastroenterology2007，13，9： | 23 |
| 2 | Oxidation of Poly- styrene Aerosols by VUV-photolysis and/or Ozone 显示文摘 | JOS'E S V JUAN L G SONJA R | 2009 | Pho- tochem Photobiol Sci2009，8，7： | 1 |
| 3 | Hh-Gli signaling pathway functions and its therapeutic potential in cancer显示文摘 | Sonja L Maja R Vasna M | 2008 | Croat Chem Aeta2008，81，1： | 1 |
| 4 | Incidence of FusariumSpecies and Mycotoxins in Silage Maize显示文摘 | Sonja E Felix E W Hans R F | 2011 | Toxins2011，3，8： | 1 |
| 5 | Modelling changes in roe deer habitat in response to forest management 显示文摘 | SONJA V SUSANNE R | 2008 | Forest Ecology and Management2008，255，： | 1 |
| 6 | Early enteral supply of fiber and lactobatilli versus conventional nutrition:A controlled trial in patients with major abdominal surgery显示文摘 | Nada R Sonja H Daniel S | 2002 | Nutrition2002，18，： | 1 |
| 7 | Hydrodenitrogenation of quinoline over carbon-supported transition-metal sulfides显示文摘 | Sonja E De Beer V H J Prins R | 1991 | Journal of Catalysis1991，127，2： | 1 |
| 8 | Substance P activates human eosinophils显示文摘 | Mieke Raap Urda Rüdrich Sonja St?nder Manuela Gehring Alexander Kapp Ulrike Raap | 2015 | Exp Dermatol2015，，： | 1 |
| 9 | Ambient Air Pollution and Lipoprotein-Associated Phospholipase A^sub 2^ in Survivors of Myocardial Infarction显示文摘 | Brüske Irene Hampel Regina Baumg?rtner Zita Rückerl Regina Greven Sonja Koenig Wolfgang Peters Annette Schneider Alexandra | 2011 | Environmental Health Perspectives2011，，7： | 1 |
| 10 | Determination of microvessel density by quantitative real-time PCR in esophageal cancer:correlation with histologic methods,angiogenic growth factor expression,and lymph node metastasis显示文摘 | Sonja L Henning C Uta R | 2007 | Clin Cancer Res2007，13，1： | 1 |
| 11 | Infective endocarditis in bicuspid aor-tic valve:atrioventricular block as sign of perivalvular abscess显示文摘 | Francesco B Sonja C Giulio R | | 0，，： | 1 |
| 12 | Analysis of the relationships between type traits and longevity in croatian simmental cattle using survival analysis显示文摘 | Sonja J Nikola R | | 0，，： | 1 |
| 13 | Experi-ment basis of determining maximum coronary, myocardialand collateral blood flow flow by pressure measurements forassessing functional stenosis severity before and after per-cutaneous transluminal coronary angioplasty 显示文摘 | PULS NH VAN SONJA KIRKEEIDE R L | 1993 | Circula-tion1993，87，4： | 1 |
| 14 | H1N1 2009 influenza virus infection during pregnancy in the USA显示文摘 | Denise J Jamieson Margaret A Honein Sonja A Rasmussen Jennifer L Williams David L Swerdlow Matthew S Biggerstaff Stephen Lindstrom Janice K Louie Cara M Christ Susan R Bohm Vincent P Fonseca Kathleen A Ritger Daniel J Kuhles Paula Eggers Hollianne Bruce H | 2009 | The Lancet2009，，9688： | 1 |
| 15 | Determination of the plant growth regulator chlormequat in food by liquid chromatography-electrospray ionisation tandem mass spectrometry显示文摘 | Jorg H Sonja R Natalia V | 2000 | J of Chroma A2000，878，12： | 1 |
| 16 | Gastrointestinal and ectoparasites from urban stray dogs in Fortaleza (Brazil): high infection risk for humans?显示文摘 | Sven Klimpel J?rg Heukelbach David Pothmann Sonja Rückert | 2010 | Parasitology Research2010，，3： | 1 |
| 17 | H1N12009 influenza virus infection during pregnancy in the USA显示文摘 | Margaret A H Sonja A R Jennifer L W | 2009 | The Lancet2009，374，9688： | 1 |
| 18 | Chirality determinationof unusual amino acids using precolumn derivatization and liquidchromatography-electrospray ionization mass spectrometry 显示文摘 | SONJA H KIRK R G DENNIS JM | | Journal of chromatography A0，，： | 1 |
| 19 | Analysis of acrylamide in food by isotopedilution liquid chromatography coupled with electrospray ionization tandem mass spectrometry 显示文摘 | SONJA R STADLER R H | 2003 | Journal of Chromatography A2003，1020，： | 1 |
| 20 | Tensions between work and home:job quality and working conditions in the institutional contexts of Germa- ny and Spain显示文摘 | Sonja D Ana M Guill6n R | 2011 | Social politics2011，18，2： | 1 |
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