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| 1 | From Green Super Rice to green agriculture:Reaping the promise of functional genomics research显示文摘Producing sufficient food with finite resources to feed the growing global population while having a smaller impact on the environment has always been a great challenge.Here,we review the concept and practices of Green Super Rice(GSR)that have led to a paradigm shift in goals for crop genetic improvement and models of food production for promoting sustainable agriculture.The momentous achievements and global deliveries of GSR have been fueled by the integration of abundant genetic resources,functional gene discoveries,and innovative breeding techniques with precise gene and whole-genome selection and efficient agronomic management to promote resource-saving,environmentally friendly crop production systems.We also provide perspectives on new horizons in genomic breeding technologies geared toward delivering green and nutritious crop varieties to further enhance the development of green agricul-ture and better nourish the world population. | Sibin Yu Jauhar Ali Shaochuan Zhou Guangjun Ren Huaan Xie Jianlong Xu Xinqiao Yu Fasong Zhou Shaobing Peng Liangyong Ma Dingyang Yuan Zefu Li Dazhou Chen Ruifeng Zheng Zhigang Zhao Chengcai Chu Aiqing You Yu Wei Susong Zhu Qiongyao Gu Guangcun He Shigui Li Guifu Liu Changhua Liu Chaopu Zhang Jinghua Xiao Lijun Luo Zhikang Li Qifa Zhang | 2022 | Molecular Plant2022，15，1： | 6 |
| 2 | Resting-state connectivity in the default mode network and insula during experimental low back pain显示文摘Functional magnetic resonance imaging studies have shown that the insular cortex has a significant role in pain identification and information integration, while the default mode network is associated with cognitive and memory-related aspects of pain perception. However, changes in the functional connectivity between the default mode network and insula during pain remain unclear. This study used 3.0 T functional magnetic resonance imaging scans in 12 healthy subjects aged 24.8 ± 3.3 years to compare the differences in the functional activity and connectivity of the insula and default mode network between the baseline and pain condition induced by intramuscular injection of hypertonic saline. Compared with the baseline, the insula was more functionally connected with the medial prefrontal and lateral temporal cortices, whereas there was lower connectivity with the posterior cingulate cortex, precuneus and inferior parietal lobule in the pain condition. In addition, compared with baseline, the anterior cingulate cortex exhibited greater connectivity with the posterior insula, but lower connectivity with the anterior insula, during the pain condition. These data indicate that experimental low back pain led to dysfunction in the connectivity between the insula and default mode network resulting from an impairment of the regions of the brain related to cognition and emotion, suggesting the importance of the interaction between these regions in pain processing. | Shanshan Zhang Wen Wu Guozhi Huang Ziping Liu Shigui Guo Jianming Yang Kangling Wang | 2014 | Neural Regeneration Research2014，9，2： | 3 |
| 3 | STRENGTH AND DUCTILITY OF Ni-Cu-BASE ALLOY MONEL K-500显示文摘STRENGTHANDDUCTILITYOFNi-Cu-BASEALLOYMONELK-500Wang;ZhixingXie;ShishuLiu;ShiguiYuan;ChaoYang;Hongcai(DepartmentofMaterialsSci... | Wang Zhixing Xie Shishu Liu Shigui Yuan Chao Yang Hongcai(Department of Materials Science and EngineeringNortheastern University, Shenyang 110006) | 1995 | 中国有色金属学会会刊:英文版1995，5，1： | 3 |
| 4 | New member of the guanosine triphosphatase activating protein family in the human epididymis显示文摘尽管没有差距在 epididymis 被探索了,在精子发生上激活蛋白质(差距) 的海鸟粪正弦 triphosphatase 的效果多年被学习了,为精子成熟的一个必要机关。在这研究,一个新差距成员,指定了为 MacGAP,在人的 epididymis 被克隆。有 70 kDa 和港口的一种通常认为的尺寸的 618 氨基酸的 Mac 差距 geneencodesaprotein 保存 RhoGAP 领域。MacGAP 的 N 终端和 C 终端肽被表示,他们的相应的反时代被准备。对 N 终端肽的反时代能检测象 0.3 ng 一样低的抗原,并且它的特性也被证实。然而,因为它的低敏感,对 C 终端肽的反时代没能检测它的抗原。Immunohistochemistry 证明 MacGAP 蛋白质依赖于 epididymis 并且有一个区域特定的表示模式,与在上皮的房间在头区域的基础节的高表示。结果在精子成熟为差距的生物效果的进一步的解释创造了一个基础。 | Xiangqi Li Qiang Liu Shigui Liu Jinsong Zhang Yonglian Zhang | 2008 | Acta Biochimica et Biophysica Sinica2008，40，10： | 3 |
| 5 | The spatiotemporal expression changes of 16 epididymis-specific genes induced by testosterone, heat, and combination treatment in cynomolgus monkey显示文摘包含阴囊的温暖的处理的试验性的不孕模型,睾丸激素植入,并且联合二被开发证实联合处理在 cynomolgus 在细菌房间 apoptosis 上导致的一个 synergistic 行动猴子睾丸。用这个模型, 16 的时间空间的表示变化报导了或在 epididymis 的新奇基因被调查在 epididymal 基因上检验处理的效果。这被表明这些区域特定的基因,其中一些地区性没被修理,随着这些处理极大地变化了。这些 epididymal 基因的表示层次波动,并且大多数基因的表示在处理的结束回到了将近正常的水平。而且,源于联合处理的表示变化不比那些源于单个处理更重要。这建议联合处理在 epididymal 基因的表示上有一个对抗行动并且它的效果不是象二个单个处理的同样在 epididymis 上不利的。 | Xiangqi Li Qiang Liu Shigui Liu Xuesen Zhang Yixun Liu Yonglian Zhang | 2008 | Acta Biochimica et Biophysica Sinica2008，40，8： | 3 |
| 6 | NONLINEAR MOTION MECHANICS MODEL OF CURVED BLOOD VESSEL显示文摘A geometric model of curved blood vessels is established based on some reason-able hypotheses;the nonlinear motion mechanics model of the curved blood vessel is establishedaccording to basic mechanics laws.This model includes much more physiological factors.It cou-ples the interaction of blood flow with mechanical factors such as the displacement,deformation,strain and stress etc.of the curved blood vessel.It is of great importance for investigating thecirculation rules of the cardiovascular system and the nonlinear pulse wave propagation in curvedblood vessels. | Qiao Aike Liu Youjun Wu Shigui Xu Xiaohu Zeng Yanjun | 2003 | Acta Mechanica Solida Sinica2003，16，1： | 3 |
| 7 | Overproduction of OsRACK1A,an effector-targeted scaffold protein promoting OsRBOHB-mediated ROS production,confers rice floral resistance to false smut disease without yield penalty显示文摘Grain formation is fundamental for crop yield but is vulnerable to abiotic and biotic stresses.Rice grain production is threatened by the false smut fungus Ustilaginoidea virens,which specifically infects rice floral organs,disrupting fertilization and seed formation.However,little is known about the molecular mechanisms of the U.virens-rice interaction and the genetic basis of floral resistance.Here,we report that U.virens secretes a cytoplasmic effector,UvCBP1,to facilitate infection of rice flowers.Mechanistically,UvCBP1 interacts with the rice scaffold protein OsRACK1A and competes its interaction with the reduced nicotinamide adenine dinucleotide phosphate oxidase OsRBOHB,leading to inhibition of reactive oxygen species(ROS)production.Although the analysis of natural variation revealed no OsRACK1A variants that could avoid being targeted by UvCBP1,expression levels of OsRACK1A are correlated with field resistance against U.virens in rice germplasm.Overproduction of OsRACK1A restores the OsRACK1A-OsRBOHB association and promotes OsRBOHB phosphorylation to enhance ROS production,conferring rice floral resistance to U.virens without yield penalty.Taken together,our findings reveal a new pathogenic mechanism mediated by an essential effector from a flower-specific pathogen and provide a valuable genetic resource for balancing disease resistance and crop yield. | Guo-Bang Li Jia-Xue He Jin-Long Wu He Wang Xin Zhang Jie Liu Xiao-Hong Hu Yong Zhu Shuai Shen Yi-Fei Bai Zong-Lin Yao Xin-Xian Liu Jing-Hao Zhao De-Qiang Li Yan Li Fu Huang Yan-Yan Huang Zhi-Xue Zhao Ji-Wei Zhang Shi-Xin Zhou Yun-Peng Ji Mei Pu Peng Qin Shigui Li Xuewei Chen Jing Wang Min He Weitao Li Xian-Jun Wu Zheng-Jun Xu Wen-Ming Wang Jing Fan | 2022 | Molecular Plant2022，15，11： | 2 |
| 8 | A natural allele of TAW1 contributes to high grain number and grain yield in rice显示文摘Grain number per panicle (GNP) is a complex trait controlled by quantitative trait loci (QTL),directly determining grain yield in rice.Identifying GNP-associated QTL is desirable for increasing rice yield.A rice chromosome segment substitution line (CSSL),F771,which showed increased panicle length and GNP,was identified in a set of CSSLs derived from a cross between two indica cultivars,R498 (recipient) and WY11327 (donor).Genetic analysis showed that the panicle traits in F771 were semidominant and controlled by multiple QTL.Six QTL were consistently identified by QTL-seq analysis.Among them,the major QTL q PLN10 for panicle length and GNP was localized to a 121-kb interval between markers N802 and N909 on chromosome 10.Based on quantitative real-time PCR and sequence analysis,TAWAWA1(TAW1),a known regulator of rice inflorescence architecture,was identified as the candidate gene for q PLN10.A near-isogenic line,NIL-TAW1,was developed to evaluate its effects.In comparison with the recurrent parent R498,NIL-TAW1 showed increased panicle length (14.0%),number of secondary branches (20.9%) and GNP (22.0%),and the final grain yield per plant of NIL-TAW1 was increased by18.6%.Transgenic experiments showed that an appropriate expression level of TAW1 was necessary for panicle development.Haplotype analysis suggested that the favorable F771-type (Hap 13) of TAW1was introduced from aus accessions and had great potential value in high-yield breeding both in indica and japonica varieties.Our results provide a promising genetic resource for rice grain yield improvement. | Hua Yuan Zhengyan Xu Xueqin Tan Peng Gao Mengya Jin Wencheng Song Shiguang Wang Yunhai Kang Peixiong Liu Bin Tu Yuping Wang Peng Qin Shigui Li Bingtian Ma Weilan Chen | 2021 | The Crop Journal2021，9，5： | 2 |
| 9 | The developmental study on the poisonous plant - Eupatorium adenophorum 显示文摘 | Hou Taiping Liu Shigui | 1999 | Foreign Animal Husbandry: Glassland Pasture1999，87，4： | 1 |
| 10 | The developmental study on the poisonous plant - Eupatorium adenophorum 显示文摘 | Hou Taiping Liu Shigui | 1999 | Foreign Animal Husbandry: Glassland Pasture1999，87，4： | 1 |
| 11 | Consructing an Amylolytic Brewing Yeast Saccharomyces pastorianus Suitable for Accelerated Brewing显示文摘 | Zengran Liu Guangyi Zhang Shigui Liu | 2004 | Journal of bioscience and bioengineering2004，98，6： | 1 |
| 12 | Improving the efficiency of hybrid combination preparation in rice breeding by a modified flowering stimulant显示文摘The utilization of hybrid vigor is an important breakthrough in the history of rice breeding.To select the best hybrid combinations,breeders manually perform extensive testing of hybridizations between restorer and sterile lines,which is a laborious and time-consuming process.Here,we report that a modified flowering stimulant containing methyl jasmonate(MeJA),6-benzylamine adenine and kinetin effectively promotes the flowering and seed set of male-sterile rice lines.Different concentrations of the ingredients were tested to identify an optimal formulation.Seed quality evaluation indicated that hybrid seeds from plants sprayed with the flowering stimulant had a higher germination rate than seeds from plants prepared by glume-cutting.In summary,the modified flowering stimulant described in this study may help reduce the labor requirement associated with hybrid rice breeding and improve yield and efficiency. | Ling Zheng Shangxing Zhang Fengyin Xue Yifan Yun Pin Liu Hua Yuan Weilan Chen Peng Qin Yuping Wang Bingtian Ma Shigui Li Yong Chen Bin Tu | 2020 | International Journal of Agricultural and Biological Engineering2020，13，3： | 1 |
| 13 | Cloning and primary characterizations of rLcn9,a new member of epididymal lipocalins in rat显示文摘Lipocalins 是保存的在结构上和具有在 epididymis 功能的潜在的重要性的蛋白质的不同地功能的家庭。老鼠 Lcn9 基因被克隆由在 silico 方法并且染色体基于相同去恒河猴 epididymal, ESC513 和它的 polyclonal antisera 被准备。老鼠 Lcn9 基因位于跨越 7 exons 的染色体 3p13,包含 2.3 kb 并且编码有 17-amino 酸信号肽的 179 氨基酸。染色分析的北污点,西方的污点,和 immunohistochemical 表明老鼠 Lcn9 是新奇 epididymis 特定的基因,在近似的头区域有选择地表示了,由钠液体影响了阴囊的因素。而且, Lcn9 蛋白质被 N-glycosylation 修改并且在头精子的 postacrosomal 领域上跳了。在结论,老鼠 Lcn9 展出了织物 -- ,区域 -- ,并且时间特定的表示模式和它的表示被钠调整阴囊的因素。它在精子成熟的潜在的角色被讨论。 | Xiangqi Li Xiaoni Zhan Shigui Liu Shuanggang Hu Chunfang Zhu Susan H.Hall Frank S.French Qiang Liu Yonglian Zhang | 2012 | Acta Biochimica et Biophysica Sinica2012，44，10： | 1 |
| 14 | Genetic variation of the genus Kengyilia by ISSR markers显示文摘We investigated the genetic variation within 32 accessions distributed to 14 species and one variety by using ISSR(inter-simple sequence repeat)markers.The results showed that genetic variation was relatively higher among the accessions.A total of 593 bands were amplified by 12 ISSR primers,of which 535 bands(90.2%)were polymorphic.Eleven to 80 polymorphic bands were amplified from each prime,with an average of 44.6 bands.The interspecies GS(genetic similarity)value ranged from 0.430 to 0.866,and the average was 0.620.Cluster analysis showed that all accessions could be classified into 4 groups by ISSR markers.The different accessions in a species were clustered together,but they had genetic variation in molecular levels.There was obvious interspecies genetic variation.Species with similar morphological characteristics and from the same areas or neighboring geographical regions were clustered together and had close relationships.ISSR markers are useful in analyzing interspecies variation in Kengyilia. | Li ZHANG Yonghong ZHOU Chunbang DING Ruiwu YANG Shigui LIU | 2008 | Frontiers in Biology2008，3，2： | 0 |
| 15 | Toxicity of Diphenyl-pentenone Against Three Aphids (Homoptera: Aphididae) and Its Effects on the Esterases and Glutathione S-transferase显示文摘The most provocative aspect of this study is its original findings on the toxicity of diphenyl-pentenone(1,5-diphenyl-2-penten-1-one, DP) against the three kinds of aphids (Macrosiphum granarium Kirby, Lipaphis erysimi(kaltenbach), Schizaphis aurantiae(Fosc.)and the inhibitory effects of DP against detoxification enzyme system of the aphid (S aurantiae). The result of bioassay in the laboratory shows that the product has strong contact activity and very good antifeeding activity, with higher efficacy than anabasine and nicotine, two botanical aphidicides. The median lethal concentrations of the three products against the apterous adult (M granarium) are 175.85, 217.23 and 245.22 mg/L, respectively, at 24 h of pest treatment. DP is inferior to methomyl in contact assay but superior in antifeeding activity assay against the three aphides. DP has strong inhibitory effects on nonspecific esterases, carboxylesterase of aphid (S aurantiae), but it can not inhibit AchE. DP also has strong inhibitory effects on glutathione S-transferase of the aphid. | 高平 Gan Mingzhe LIU Shigui | 2004 | High Technology Letters2004，10，3： | 0 |
| 16 | Isolation, Purification and Identification of the Spermicidal Active Compound from Neem Oil显示文摘Bioassay-directed fractionation of the chloroform extract of the neem oil has resulted in the isolation of one new esters derivatives named 2-Octadecanoic acid-4-Palmitic acid-2,4-Pentanediyl ester (compound 1). Its structure is deduced on the basis of spectroscopic evidence. The test of in vitro spermicidal activity of the compound 1 shows that the compound 1 can kill all sperms of Kunming mice in vitro in less than 20 sec at the concentration of 2mg/ml. | 殷中琼 Gao Ping Gao Rong Jiang Dehong Liu Kun LIU Shigui | 2004 | High Technology Letters2004，10，3： | 0 |
| 17 | Antagonism and Molecular Identification of an Antibiotic Bacterium BS04 Against Phytopathogenic Fungi and Bacteria显示文摘Through a modified agar well diffusion assay, antagonism of bacterium BS04 is tested. The data show that BS04 has antibiotic activity against phytopathogenic fungi and bacteria, including Phoma wasabiae Yokogi, Cochlibolus Heterostrophu, Exserohilum Turcicum, Curuvularia Lunata (Walk) Boed, Thantephorus cucumris, Fusarium graminearum, Xanthomonas axonopodis pv. Citri (Hasse) Dye and Xanthomonas zingiberi (Uyeda) Savulescu. The products of bacterium BS04 can endure the treatment of a wide range of pH, and maintain the antibiotic activity after treatment of 100℃ for 30 min. The result suggests that bacterium BS04 has the potential as a promising biocontrol agent. In order to determine the taxonomic placement, the molecular identification of BS04 is performed. The comparative analysis of 16s rDNA sequences indicates that the 16s rDNA sequence of BS04 is highly homologous with sequences of typical Paenibacillus bacteria from the RPD library (from 92% to 99%). And the constructed phylogenetic tree by using maximum-likelihood method with Bootstrap Trial 1000 proves that BS04 is subjected to Paenibacillus polymyxa. | 谢晶 Ge Shaorong Tao Yong Gao Ping Liu Kun LIU Shigui | 2004 | High Technology Letters2004，10，3： | 0 |
| 18 | Wide grain 4,encoding an alpha-tubulin,regulates grain size by affecting cell expansion in rice显示文摘Rice is one of the three most important food crops in the world.Increasing rice yield is an effective way to ensure food security.Grain size is a key factor affecting rice yield;however,the genetic and molecular mechanisms regulating grain size have not been fully investigated.In this study,we identified a rice mutant,wide grain 4-D(wg4-D),that exhibited a significant increase in grain width and a decrease in grain length.Histological analysis demonstrated that WG4 affects cell expansion thereby regulating grain size.MutMap-based gene mapping and complementary transgenic experiments revealed that WG4 encodes an alpha-tubulin,OsTubA1.A SNP mutation in WG4 affected the arrangement of cortical microtubules and caused a wide-grain phenotype.WG4 is located in nuclei and cytoplasm and expressed in various tissues.Our results provide insights into the function of tubulin in rice and identifies novel targets the regulation of grain size in crop breeding. | Yi Liu Lianan Guo Guoli Qu Yang Xiang Xu Zhao Hua Yuan Ting Li Liangzhu Kang Shiwen Tang Bin Tu Bingtian Ma Yuping Wang Shigui Li Weilan Chen Peng Qin | 2023 | The Crop Journal2023，11，6： | 0 |
| 19 | A Severe Seasonal Influenza Epidemic During 2017–2018 in China After the 2009 Pandemic Influenza: A Modeling Study显示文摘Influenza viruses continue to cause epidemics worldwide every year.However,due to the lack of an effective assessment for the severity of influenza epidemics,it was extremely difficult to take preventative measures.Data were extracted from infectious diseases reports from 2011–2018.Joinpoint regression model and susceptible-exposed-infectious-recovered model were built to understand the characteristics and processes of the epidemic.The reported incidence of influenza was 1,913,698 from January 2011 to February 2018,with an average-yearly-reported-incidence-rate of 19.21 per 100,000.However,there had been a substantial nationwide epidemic of influenza after September 2017,when the average yearly reported incidence rate was 87.29 per 100,000 and an annual percentage change of 48.1%.The hemagglutinin genes of most influenza A(H1N1 and H3N2)viruses from the period of the epidemic had lower homology to those before August 2017.All the hemagglutinin of the recommended A(H3N2,H1N1)and B(Victoria)viruses for vaccines 2017/2018 had low matches with the epidemic viruses.The basic reproduction number was 1.53.The vaccination benefit was linearly related to vaccination coverage,while the quarantine measure had only significantly benefited when over 60%of the quarantined population.The most severe epidemic of influenza in China since 2011 occurred during the period from September 2017 to February 2018.Compared to quarantine,influenza vaccination is more effective way to prevent influenza,and strategies to increase vaccination coverage should be taken for the prevention of severe epidemics of influenza. | Xiaofang Fu Yuqing Zhou Jie Wu Xiaoxiao Liu Cheng Ding Chenyang Huang Min Deng Dongyan Shi Chencheng Wang Kaijin Xu Jingjing Ren Bing Ruan Lanjuan Li Shigui Yang | 2019 | Infectious Microbes & Diseases2019，1，1： | 0 |
| 20 | Nursing care of 25 children with Kawasaki disease显示文摘Objective The aim of this study is to estimate the incidence and describe the diagnosis,treatment and nursing care of Kawasaki Disease among children in Guilin city,Guangxi Province,China.The study is also designed to assess clinical aspects of retrospection,management and outcome,specifically in relation to cardiac disease.Methods To retrospectively collected the clinical data of pediatric patients with Kawasaki's disease at the Affiliated Hospital of Guilin Medical University in China,which covered a two-year period from 2015 to 2016.Results During the two-year study period,a total of 25 cases of Kawasaki disease were reported in the hospitals,comprising of 11 boys and 14 girls(male-female ratio was 1∶1.27).The seasonal distribution showed a slightly higher incidence in spring and summer.The patients’mean age of onset was 2.78 years old.The average hospitalization days of patients were 8.08(range from 5 to18days).16 Kawasaki patients were diagnosed as bronchial pneumonia.Coronary arterial abnormalities were detected during follow up by UCG in 5 cases,but no coronary artery aneurysm was found.All 25 patients recovered and were discharged from the hospital.Conclusion Early treatment and proper nursing management are key issues to prevent the occurrence of coronary artery aneurysm in Kawasaki Disease patients. | LI Shenmei GAO Yan LI Yuan ZHAO Jia LIU Chunying ZHONG Shigui | 2017 | 中西医结合护理(中英文)2017，3，12： | 0 |
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