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| 1 | Consensus on the application of negative pressure wound therapy of diabetic foot wounds显示文摘Because China is becoming an aging society,the incidence of diabetes and diabetic foot have been increasing.Diabetic foot has become one of the main health-related killers due to its high disability and mortality rates.Negative pressure wound therapy(NPWT)is one of the most effective techniques for the treatment of diabetic foot wounds and great progress,both in terms of research and its clinical application,has been made in the last 20 years of its development.However,due to the complex pathogenesis and management of diabetic foot,irregular application of NPWT often leads to complications,such as infection,bleeding and necrosis,that seriously affect its treatment outcomes.In 2020,under the leadership of Burns,Trauma and Tissue Repair Committee of the Cross-Straits Medicine Exchange Association,the writing group for‘Consensus on the application of negative pressure wound therapy of diabetic foot wounds’was established with the participation of scholars from the specialized areas of burns,endocrinology,vascular surgery,orthopedics and wound repair.Drawing on evidence-based practice suggested by the latest clinical research,this consensus proposes the best clinical practice guidelines for the application and prognostic evaluation of NPWT for diabetic foot.The consensus aims to support the formation of standardized treatment schemes that clinicians can refer to when treating cases of diabetic foot. | Shizhao Ji Xiaobin Liu Jie Huang Junmin Bao Zhaohong Chen Chunmao Han Daifeng Hao Jingsong Hong Dahai Hu Yufeng Jiang Shang Ju Hongye Li Zongyu Li Guangping Liang Yan Liu Gaoxing Luo Guozhong Lv Xingwu Ran Zhongmin Shi Juyu Tang Aiping Wang Guangyi Wang Jiangning Wang Xin Wang Bing Wen Jun Wu Hailin Xu Maojin Xu Xiaofei Ye Liangxi Yuan Yi Zhang Shichu Xiao Zhaofan Xia | 2021 | Burns & Trauma2021，9，1： | 17 |
| 2 | A New Method for Wind-induced Response Analysis of Long Span Roofs显示文摘 | Wu Yue Shen Shizhao | 2006 | International Journal of Space Structures2006，21，2： | 1 |
| 3 | Nonlinear Coupling of Reversed Shear Alfvén Eigenmode and Toroidal Alfvén Eigenmode during Current Ramp显示文摘Two novel nonlinear mode coupling processes for reversed shear Alfvén eigenmode(RSAE) nonlinear saturation are proposed and investigated. In the first process, the RSAE nonlinearly couples to a co-propagating toroidal Alfvén eigenmode(TAE) with the same toroidal and poloidal mode numbers, and generates a geodesic acoustic mode. In the second process, the RSAE couples to a counter-propagating TAE and generates an ion acoustic wave quasi-mode. The condition for the two processes to occur is favored during current ramp. Both the processes contribute to effectively saturate the Alfvénic instabilities, as well as nonlinearly transfer of energy from energetic fusion alpha particles to fuel ions in burning plasmas. | Shizhao Wei Yahui Wang Peiwan Shi Wei Chen Ningfei Chen Zhiyong Qiu | 2021 | Chinese Physics Letters2021，38，3： | 1 |
| 4 | A new method for wind-induced response analysis of long span roofs 显示文摘 | Chen Bo Wu Yue Shen Shizhao | 2006 | International Journal of Space Structures2006，21，2： | 1 |
| 5 | A new method for wind-induced response analysis of long span roofs 显示文摘 | Chen Bo Wu Yue Shen Shizhao | 2006 | International Journal of Space Structures2006，21，2： | 1 |
| 6 | A new method for windinduced response analysis of long span roofs显示文摘 | Chen Bo Wu Yue Shen Shizhao | 2006 | International Journal of Space Structures2006，21，2： | 1 |
| 7 | Research on stability of reticulated shell structure显示文摘 | Shen Shizhao Chen Ting | 2009 | Beijing:Science Press2009，，： | 1 |
| 8 | A new method for wind-induced response analysis of long span roofs显示文摘 | Chen Bo Wu Yue Shen Shizhao | 2006 | International Journal of Space Structures2006，21，2： | 1 |
| 9 | Wind-induced Response Analysis of Conical Membrane Structures显示文摘 | Chen Bo Wu Yue Shen Shizhao | 2005 | Journal of Harbin Institute of Technology2005，5，12： | 1 |
| 10 | Construction of regulatory network for alopecia areata progression and identification of immune monitoring genes based on multiple machine-learning algorithms显示文摘Objectives Alopecia areata(AA)is an autoimmune-related non-cicatricial alopecia,with complete alopecia(AT)or generalized alopecia(AU)as severe forms of AA.However,there are limitations in early identification of AA,and intervention of AA patients who may progress to severe AA will help to improve the incidence rate and prognosis of severe AA.Methods We obtained two AA-related datasets from the gene expression omnibus database,identified the differentially expressed genes(DEGs),and identified the module genes most related to severe AA through weighted gene co-expression network analysis.Functional enrichment analysis,construction of a protein–protein interaction network and competing endogenous RNA network,and immune cell infiltration analysis were performed to clarify the underlying biological mechanisms of severe AA.Subsequently,pivotal immune monitoring genes(IMGs)were screened through multiple machine-learning algorithms,and the diagnostic effectiveness of the pivotal IMGs was validated by receiver operating characteristic.Results A total of 150 severe AA-related DEGs were identified;the upregulated DEGs were mainly enriched in immune response,while the downregulated DEGs were mainly enriched in pathways related to hair cycle and skin development.Four IMGs(LGR5,SHISA2,HOXC13,and S100A3)with good diagnostic efficiency were obtained.As an important gene of hair follicle stem cells stemness,we verified in vivo that LGR5 downregulation may be an important link leading to severe AA.Conclusion Our findings provide a comprehensive understanding of the pathogenesis and underlying biological processes in patients with AA,and identification of four potential IMGs,which is helpful for the early diagnosis of severe AA. | Jiachao Xiong Guodong Chen Zhixiao Liu Xuemei Wu Sha Xu Jun Xiong Shizhao Ji Minjuan Wu | 2023 | Precision Clinical Medicine2023，6，2： | 1 |
| 11 | A new method for wind-induced response analysis of long span roofs 显示文摘 | Chen Bo Wu Yue Shen Shizhao | 2006 | International Journal of Space Structures2006，21，2： | 1 |
| 12 | A new method for wind-induced response analysis of long span roofs显示文摘 | Chen Bo Wu Yue Shen Shizhao | 2006 | International Journal of Space Structures2006，21，2： | 1 |
| 13 | Diagnostic value of genetic mutation analysis and mutation profiling of cell-free DNA in intraocular fluid for vitreoretinal lymphoma显示文摘Dear editor,Vitreoretinal lymphoma(VRL)is a rare intraocular malignant lymphoma affecting the vitreous and/or retina.Pathological diagnosis is challenging.Retinal biopsies have high risks of irreversible visual impairment(even blind-ness),which are not used in clinics for patients with residual visual function.The limited cellular yield from vit-reous biopsies and the cell lysis also contribute to the low detection rates of VRL using cytopathology[1]. | Xiaoqing Chen Yunwei Hu Wenru Su Shizhao Yang Xiaoxiao Wang Ping Zhang Xiaoyu Hong Chuqiao Liang Zhuyun Qian Ziqiang Li Yong Tao Huiqiang Huang Dan Liang | 2022 | Cancer Communications2022，42，11： | 1 |
| 14 | Electro-chemo-mechanical design of polymer matrix in composited LiNi_(0.8)Co_(0.1)Mn_(0.1)O_(2) cathode endows solid-state batteries with superior performance显示文摘Nickel-rich LiNi_(0.8)Co_(0.1)Mn_(0.1)O_(2)(NCM811) cathode material has been widely concerned due to its high voltage,high specific capacity and excellent rate performance,which is considered as one of the most promising cathode materials for the next generation of high-energy-density solid-state lithium batteries.However,serious electro-chemo-mechanical degradation of Nickel-rich cathode during cycling,especially at a high voltage(over 4.5 V),constrains their large-scale application.Here,using the multiphysical simulation,highly-conductive polymer matrix with spontaneous stress-buffering effect was uncovered theoretically for reinforcing the electrochemical performance of composited NCM81 1 cathode through the visualization of uniform concentration distribution of Li-ion coupled with improved stress field inside NCM811 cathode.Thereupon,polyacrylonitrile(PAN) and soft polyvinylidene fluoride(PVDF) were selected as the polymer matrix to fabricate the composited NCM811 cathode(PVDFPAN@NCM811) for improving the electrochemical performance of the solid-state NMC811|Li full cells,which can maintain high capacity over 146.2 mA h g^(-1)after 200 cycles at a high voltage of 4.5 V.Suggestively,designing a multifunctional polymer matrix with high ionic conductivity and mechanical property can buffer the stress and maintain the integrity of the structure,which can be regarded as the door-opening avenue to realize the high electrochemical performance of Ni-rich cathode for solidstate batteries. | Haolong Jiang Xieyu Xu Qingpeng Guo Hui Wang Jiayi Zheng Yuhao Zhu Huize Jiang Olesya O.Kapitanova Valentyn S.Volkov Jialin Wang Yaqi Chen Yongjing Wang Yu Han Chunman Zheng Kai Xie Shizhao Xiong Yangyang Liu Xingxing Jiao | 2023 | Journal of Energy Chemistry2023，，3： | 0 |
| 15 | Viability of all-solid-state lithium metal battery coupled with oxide solid-state electrolyte and high-capacity cathode显示文摘Owing to the utilization of lithium metal as anode with the ultrahigh theoretical capacity density of 3860 mA h g^(-1)and oxide-based ceramic solid-state electrolytes(SE),e.g.,garnet-type Li7La_(3)Zr_(2)O_(12)(LLZO),all-state-state lithium metal batteries(ASLMBs)have been widely accepted as the promising alternatives for providing the satisfactory energy density and safety.However,its applications are still challenged by plenty of technical and scientific issues.In this contribution,the co-sintering temperature at 500℃is proved as a compromise method to fabricate the composite cathode with structural integrity and declined capacity fading of LiNi_(0.5)Co_(0.2)Mn_(0.3)O_(2)(NCM).On the other hand,it tends to form weaker grain boundary(GB)inside polycrystalline LLZO at inadequate sintering temperature for LLZO,which can induce the intergranular failure of SE during the growth of Li filament inside the unavoidable defect on the interface of SE.Therefore,increasing the strength of GB,refining the grain to 0.4μm,and precluding the interfacial defect are suggested to postpone the electro-chemo-mechanical failure of SE with weak GB.Moreover,the advanced sintering techniques to lower the co-sintering temperature for both NCM-LLZO composite cathode and LLZO SE can be posted out to realize the viability of state-of-the-art ASLMBs with higher energy density as well as the guaranteed safety. | Xingxing Jiao Xieyu Xu Yongjing Wang Xuyang Wang Yaqi Chen Shizhao Xiong Weiqing Yang Zhongxiao Song Yangyang Liu | 2024 | Journal of Energy Chemistry2024，91，4： | 0 |
| 16 | FlowDNN:a physics-informed deep neural network for fast and accurate flow prediction显示文摘For flow-related design optimization problems,e.g.,aircraft and automobile aerodynamic design,computational fluid dynamics(CFD)simulations are commonly used to predict flow fields and analyze performance.While important,CFD simulations are a resource-demanding and time-consuming iterative process.The expensive simulation overhead limits the opportunities for large design space exploration and prevents interactive design.In this paper,we propose Flow DNN,a novel deep neural network(DNN)to efficiently learn flow representations from CFD results.Flow DNN saves computational time by directly predicting the expected flow fields based on given flow conditions and geometry shapes.Flow DNN is the first DNN that incorporates the underlying physical conservation laws of fluid dynamics with a carefully designed attention mechanism for steady flow prediction.This approach not only improves the prediction accuracy,but also preserves the physical consistency of the predicted flow fields,which is essential for CFD.Various metrics are derived to evaluate Flow DNN with respect to the whole flow fields or regions of interest(RoIs)(e.g.,boundary layers where flow quantities change rapidly).Experiments show that Flow DNN significantly outperforms alternative methods with faster inference and more accurate results.It speeds up a graphics processing unit(GPU)accelerated CFD solver by more than 14000×,while keeping the prediction error under 5%. | Donglin CHEN Xiang GAO Chuanfu XU Siqi WANG Shizhao CHEN Jianbin FANG Zheng WANG | 2022 | Frontiers of Information Technology & Electronic Engineering2022，23，2： | 0 |
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