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| 1 | Fine particulate matter(PM_(2.5)/PM_(1.0)) in Beijing,China: Variations and chemical compositions as well as sources显示文摘Particulate matter(i.e.,PM_(1.0) and PM_(2.5)),considered as the key atmospheric pollutants,exerts negative effects on visibility,global climate,and human health by associated chemical compositions.However,our understanding of PM and its chemical compositions in Beijing under the current atmospheric environment is still not complete after witnessing marked alleviation during 2013–2017.Continuous measurements can be crucial for further air quality improvement by better characterizing PM pollution and chemical compositions in Beijing.Here,we conducted simultaneous measurements on PM in Beijing during 2018–2019.Results indicate that annualmean PM_(1.0) and PM_(2.5) concentrations were 35.49±18.61μg/m^(3) and 66.58±60.17μg/m^(3),showing a positive response to emission controls.The contribution of sulfate,nitrate,and ammonium(SNA)played an enhanced role with elevated PM loading and acted as the main contributors to pollution episodes.Discrepancies observed among chemical species between PM_(1.0) and PM_(2.5) in spring suggest that sand particles trend to accumulate in the range of 1–2.5μm.Pollution episodes occurred accompanied with southerly clusters and high formation of SNA by heterogeneous reactions in summer and winter,respectively.Results from positive matrix factorization(PMF)combined with potential source contribution function(PSCF)models showed that potential areas were seasonal dependent,secondary and vehicular sources became much more important compared with previous studies in Beijing.Our study presented a continuous investigation on PM and sources origins in Beijing,which provides a better understanding for further emission control as well as a reference for other cities in developing countries. | Lining Luo Xiaoxuan Bai Shuhan Liu Bobo Wu Wei Liu Yunqian Lv Zhihui Guo Shumin Lin Shuang Zhao Yan Hao Jiming Hao Kai Zhang Aihua Zheng Hezhong Tian | 2022 | Journal of Environmental Sciences2022，34，11： | 3 |
| 2 | A Novel Electric Dual Motor Transmission for Heavy Commercial Vehicles显示文摘As a vital vehicle part,the powertrain system is undergoing a fast transition towards electrification.The new integrated electric drive system has been widely used,especially for passenger cars.In this work,a novel electric dual motor transmission is proposed for heavy commercial vehicles.The transmission scheme is firstly introduced,which can achieve 9 different operating modes including 5 single motor modes and 4 dual motor modes.Then,the mode shift map with minimum energy consumption is designed based on the motor efficiency map and the proposed energy management strategy.The driving power is appropriately distributed between the two motors in dual motor modes under the condition of minimum power consumption.In addition,a coordinated control strategy is developed for mode shift control without power interruption.The results show that the electric dual motor transmission has advantages in power consumption and power shift ability compared with the conventional single motor automated manual transmission. | Xiangyang Xu Jiajia Liang Qingjun Hao Peng Dong Shuhan Wang Wei Guo Yanfang Liu Zhonghua Lu Jiantao Geng Bin Yan | 2021 | Automotive Innovation2021，4，1： | 2 |
| 3 | Supramolecular Prodrug Micelles Constructed by Drug-Drug Conjugate with Water Soluble Pillar[6]arene for Controllable and Rapid Drug Release显示文摘The first attempt of constructing supramolecular prodrug micelles based on the host-guest interaction between water-soluble pillar[6]arene(WP6)and a novel doxorubicin(DOX)-based drug-drug conjugate(G)is reported,in which the drug-drug conjugate is synthesized by conjugating anticancer drug DOX with another drug isoniazide via the acid-cleavable hydrazone bond.The obtained WP6⊃G micelles are stable under physiological conditions,whereas the cumulative release of DOX is approximate to 100%within 30 min at pH 5.5 by simulating the endo-lysosomal environment at 37℃.Therefore,this WP6-based prodrug micelles can achieve efficient DOX ac-cumulation in the acidic tumor cells within a short period of time,which is very important and valuable;meanwhile it can also reduce the unexpected premature burst release under physiological condition.Furthermore,cellular in-ternalization and localization experiments demonstrated that these prodrug micelles enter cancer cells mainly via endocytosis and can lead to significant drug accumulation in SKOV3 cancer cells,implying its promising future for cancer therapy. | Yu Cao Xiaochun Zou Shuhan Xiong Yan Li Yingzhong Shen Xiaoyu Hu Leyong Wang | 2015 | Chinese Journal of Chemistry2015，33，3： | 2 |
| 4 | Transient inhibition of foot-and-mouth disease virus replication by siRNAs silencing VP1 protein coding region显示文摘 | Ke Lv Yingjun Guo Yiliang Zhang Kaiyu Wang Ka Li Yan Zhu Shuhan Sun | 2008 | Research in Veterinary Science2008，，3： | 1 |
| 5 | Two main metabolites of gentiopicroside detected in rat plasma by LC-TOF-MS following 2, 4-dinitrophenylhydrazine derivatization显示文摘 | Zhigang Wang Shuhan Tang Yan Jin Yan Zhang Masao Hattori Hailong Zhang Ning Zhang | 2014 | Journal of Pharmaceutical and Biomedical Analysis2014，，： | 1 |
| 6 | Methylation‐induced loss of miR ‐484 in microsatellite‐unstable colorectal cancer promotes both viability and IL ‐8 production via CD137L显示文摘 | Qian Mei Geng Xue Xiang Li Zhiqiang Wu Xiaolei Li Hongli Yan Mingzhou Guo Shuhan Sun Weidong Han | 2015 | J. Pathol2015，，2： | 1 |
| 7 | MDM 2 is a useful prognostic biomarker for resectable gastric cancer显示文摘 | Yang Ye Xuan Li Jingjing Yang Shuhan Miao Shouyu Wang Yansu Chen Xiaowei Xia Xuming Wu Jianbing Zhang Yan Zhou Song He Yongfei Tan Fulin Qiang Gang Li Oluf Dimitri R?e Jianwei Zhou | 2013 | Cancer Sci2013，，5： | 1 |
| 8 | Anti-inflammatory effects of ivermectin in mouse model of allergic asthma显示文摘 | Shuhan Yan Xinxin Ci Na Chen | 2011 | Inflamm Res2011，60，： | 1 |
| 9 | Doramectin inhibits the LP-S-induced inflammatory response in vitro and in vivo显示文摘 | Shuhan Yan Xinxin Ci Na Chen | 2012 | Vet Parasitol2012，99，5： | 1 |
| 10 | Cloning and functional identification of a novel annexin subfamily in cysticereus cellulosae 显示文摘 | Yan Hongli Sun Shuhan Chen Ruiwen | 2002 | Mol Biochem Parasitol2002，119，1： | 1 |
| 11 | p53 Promoter-based Reporter Gene in vitro Assays for Quick Assessment of Agents with Genotoxic Potential显示文摘p53 基于倡导者的绿荧光灯的蛋白质(GFP ) 和酶记者基因试金为检测 genotoxic 代理人导致的 DNA 损坏被建立了。Toevaluate 系统,有任何一个 pHP53-GFP 的 NIH3T3 房间 transfected 或 pMP53-GFP 构造与 mitomycin 或 5 氟尿嘧啶被对待。GFP 记者基因的表示显著地并且明确地在暴露于 mitomycin 或 5 氟尿嘧啶的房间被导致。然后,我们对待在各种各样的集中与 mitomycin, 5 氟尿嘧啶或 cisplatia 怀有 pHP53-Luc 或 pMP53-Luc 向量的 NIH3T3cells。同样,到有 genotoxic 潜力的这些代理人的房间的暴露在酶记者基因表达导致了剂量依赖者正式就职。因此,这些能为快评价在 vitro 记者基因试金提供一个理想的系统或代理人 withgenotoxic 潜力屏蔽。 | Huaixing LI Ke SHI Ruiwen CHEN Yan HE Dan WU Shuhan SUN | 2007 | Acta Biochimica et Biophysica Sinica2007，39，3： | 0 |
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