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| 1 | Protein microarrays for systems biology显示文摘系统生物学为在系统水平上理解生物系统拿钥匙。它最后为象癌症,糖尿病,肥胖,心理混乱,和许多其它那样的复杂疾病的治疗和痊愈拿钥匙。-omics' 技术例如 genomics, transcriptomics, proteomics,和 metabonomics,在系统生物学的主要驱动力之中。是展示了高产量,使小型化,并且能够平行分析,蛋白质 microarrays 已经为系统成为了一个重要技术平台生物学。在这评论,我们将用蛋白质 microarrays 集中于系统水平或生物系统的全球分析。蛋白质 microarrays 的四种主要类型将被讨论:proteome microarrays,抗体 microarrays,反向阶段的蛋白质数组,和 lectin microarrays。我们将也为系统生物学讨论挑战和蛋白质 microarray 技术和他们的应用的未来方向。我们强烈相信蛋白质 microarrays 将很快为系统生物学成为一个不可缺少、无价的工具。 | Lina Yang | 2011 | Acta Biochimica et Biophysica Sinica2011，43，3： | 9 |
| 2 | Construction of a metabolomics profile of arsenic trioxide effect in gastric carcinoma cell line SGC7901显示文摘砷三氧化物(ATO ) 为对待尖锐 promyelocytic 白血病是高度有效的。它也为治疗稳固的肿瘤保持诺言,包括胃的癌。然而,到稳固的肿瘤的 ATO 的有效性的分子的机制仍然糟糕被理解。在这研究,我们 chosed 是的胃的癌一个例子并且试着通过 metabolomics 揭示 antitumor 机制。胃的癌房间线 SGC7901 为 6, 12,和 24 h 与 ATO 被对待。全球代谢物侧面被 metabolomics 分析用气体监视层析(GC )/mass spectrometry (MS ) 和液体层析 /MS/MS。281 的一个总数证明代谢物可靠地被检测。生物信息学分析证明那 glycerophospholipid 合成,一个碳合成,和谷胱甘肽合成戏剧性地被影响。被影响了的另外的细胞的功能 / 小径包括了煽动性的反应,菸碱腺嘌 dinucleotide (NAD +), 和 polyamine 生合成小径。在有以前的 transcriptomics 和 proteomics 数据的联合,从这研究的 metabolomics 数据能为 ATO 处理的特定的 antitumor 机制的理解用作珍贵资源。 | Ziqing Chen Hainan Zhang Lina Yang Hewei Jiang Shujuan Guo Yang Li Shengce Tao | 2016 | Acta Biochimica et Biophysica Sinica2016，48，5： | 5 |
| 3 | Development of High Sensitivity Eight-Element Multiplexed Fiber Laser Acoustic Pressure Hydrophone Array and Interrogation System显示文摘纤维激光水中听音器由于唯一的优点和宽广申请前景得到了普遍担心。在这篇论文,研究八元素的多路的纤维激光结果声学的压力数组和讯问系统被介绍,包含的低噪音的分布式的反馈纤维激光(DFB-FL ) 制造,包装的敏感改进,和 interferometric 表明解调。系统的频率反应范围是 10Hz-10kHz,声学的压力敏感到达的激光频率 115 dB re Hz/Pa,和声学的压力是的相等的噪音不到 60Pa/Hz 1/2 。系统的动态范围比 120 dB 大。 | Ming LI Zhihui SUN Xiaolei ZHANG Shujuan LI Zhiqiang SONG Meng WANG Jian GUO Jiasheng NI Chang WANG Gangding PENG Xiangang XU | 2017 | Photonic Sensors2017，7，3： | 4 |
| 4 | Effect of competition on spatial patterns of oak forests on the Chinese Loess Plateau显示文摘Reforestation or natural forest regeneration is an alternative measure for controlling soil erosion in degraded land on the Chinese Loess Plateau(CLP). However, our understanding of the temporal dynamics and the spatial patterns of forest regeneration remains inadequate. Two oak forests at different development stages were investigated to determine the spatial patterns of competitions(intraspecies and interspecies) during different successional stages. The intraspecies and interspecies spatial relationships among different tree diameters at breast height were analyzed at multiple scales by Kriging interpolation method and univariate and bivariate O-ring statistics. Our analytical results indicated that self-correlation and competition intensity were relatively high between oak and pine trees in the early development stage of oak forests due to their clumped distributions of heavy seeds. Birch trees had a lower competition in comparison to oak trees although birch was the dominant species. Therefore, asymmetric competition of oak trees was most likely to have led to their edge dispersal and their success in replacing the pioneer species. Asymmetric competition means that larger individuals obtained a disproportionately large share of the resources and suppressed the growth of smaller individuals. Kriging interpolation analysis showed a tendency towards homogenization caused by interspecies competition during the succession of oak forests. Our results demonstrated that the competition was the driving factor in the spatial distribution of oak forests on the CLP. | KANG Di DENG Jian QIN Xiaowei HAO Fei GUO Shujuan HAN Xinhui YANG Gaihe | 2017 | Journal of Arid Land2017，9，1： | 3 |
| 5 | Photothermally Responsive Conjugated Polymeric Singlet Oxygen Carrier for Phase Change-Controlled and Sustainable Phototherapy for Hypoxic Tumor显示文摘Hypoxia significantly compromises the therapeutic performance of photodynamic therapy(PDT)owing to the oxygen level which plays a key role in the production of singlet oxygen(^(1)O_(2)).Herein,the photothermally responsive phase change materials(PCM)are used to encapsulate 1,4-dimethylnaphthalene-functionalized platinum(II)-acetylide conjugated polymer(CP1)with intense nearinfrared(NIR)absorption to prepare new ^(1)O_(2) nanocarriers(CP1-NCs).The 1,4-dimethylnaphthalene moieties in CP1-NCs can trap the ^(1)O_(2) produced from CP1 under irradiation and form a stable endoperoxide.Then,the endoperoxide undergoes cycloreversion to controllably release ^(1)O_(2) via the NIR light-triggered photothermal effect of CP1 and controllable phase change of PCM,which can be used for oxygen-independent PDT for hypoxic tumor.Furthermore,the in vivo luminescence imagingguided synergistic PDT and photothermal therapy showed better efficiency in tumor ablation.The smart design shows the potent promise of CP1-NCs in PCM-controlled and sustainable phototherapy under tumor hypoxic microenvironment,providing new insights for constructing oxygen-independent precise cancer phototherapeutic platform. | Guo Li Ruyi Zhou Weili Zhao Bo Yu Jie Zhou Shujuan Liu Wei Huang Qiang Zhao | 2020 | Research2020，，1： | 3 |
| 6 | Intake of Vitamin A,Thiamine,Riboflavin,Vitamin C,and Niacin Among Children Aged 6−11 Years Old—China,2016−2017显示文摘Summary What is already known on this topic?Insufficient intake of vitamins is one of the major nutritional problems in children aged 6-11 years old in China,and the problem is particularly severe for rural populations.What is added by this report?Among children aged 6-11 years old in 2016-2017,the average intakes of vitamin A,thiamine. | Wei Piao Lahong Ju Hongyun Fang Qiya Guo Shuya Cai Xiaoli Xu Shujuan Li Xue Cheng Liyun Zhao Dongmei Yu | 2021 | China CDC weekly2021，3，11： | 3 |
| 7 | Cooking Oil and Salt Intakes Among Children Aged 6−17 Years——China,2016−2017显示文摘Summary What is already known on this topic?High-level intakes of both cooking oil and salt are issues of concern in China as they can lead to an increased risk of chronic diseases later in life.Reducing intakes of cooking oil and salt should be prioritized in children.What is added by this report?Among children aged 6-17 years in China in 2016-2017,the median intake of cooking oil and salt were 27.7 and 6.1 g/d,respectively.The percentages of children with intake of cooking oil and salt that exceeded the recommended guidelines were 50.4%and 67.8%,respectively. | Lahong Ju Dongmei Yu Wei Piao Hongyun Fang Qiya Guo Xiaoli Xu Shujuan Li Xue Cheng Shuya Cai Liyun Zhao | 2021 | China CDC weekly2021，3，31： | 3 |
| 8 | A missing link of the Proto-Tethys Ocean between the Qinling and Qilian orogens,China:Insights from geochronology and structural geology显示文摘The Qinling-Qilian connection zone(QQCZ)is a key area to reveal the relationship and to make a link of the North Qinling and the North Qilian orogens,China.Here we present U-Pb dating data of detrital zircons from four sedimentary/metasedimentary rocks in the QQCZ and the southwestern North China Block(NCB)and detailed regional structural data.Three episodes of fold deformation(D1,D2 and D3)are distinguished in the QQCZ,with the former two occurred during the early Paleozoic.The D1 deformation is mainly characterized by regionally penetrative schistosity and some residual rootless intrafolial folds due to the intensive superpositions by the subsequent D2 and D3 deformations.The D2 deformation characterized by tight folds,associated axial plane foliations and crenulation lineations indicates a stress field characterized by NNE-SSW-directed compression,which may be induced by the collision between the NCB and the southern blocks.The D3 deformation which might occur during the Mesozoic is marked by upright open folds and kink bands.The similarity of the detrital zircon age spectra of the Huluhe Group in the North Qilian Orogen and the Erlangping Group in the North Qinling Orogen suggests that the two groups have similar provenance,which may indicate that the North Qilian Orogen corresponded to the North Qinling Orogen in a regional tectonic framework.In addition,the remarkable age peak at^435 Ma of the detrital zircon age spectrum of the Duanjiaxia Formation in the southwestern NCB indicates that this formation obtained the provenance of the North Qilian and North Qinling orogens,which may be generated by the collage of the southwestern NCB and the QQCZ during the Late Ordovician-Early Silurian.Based on structural,detrital zircon and metamorphic data,we suggest that the North Qilian and North Qinling orogens underwent similar evolution during the early Paleozoic due to the closure of the North Qilian and the Kuanping oceans which located at the northern boundary of the Proto-Tethys Ocean. | Shujuan Zhao Sanzhong Li Huahua Cao Xiyao Li Xin Liu Shengyao Yu Xiaoyu Guo | 2020 | Geoscience Frontiers2020，11，5： | 2 |
| 9 | Recyclable polymer-based nano-hydrous manganese dioxide for highly efficient Tl(I) removal from water显示文摘Tl(I)in water even at a trace level is fatal to human beings and the ecosystem.Here we fabricated a new polymer-supported nanocomposite(HMO-001)for efficient Tl(I)removal by encapsulating nanosized hydrous manganese dioxide(HMO)within a polystyrene cation exchanger(D-001).The resultant HMO-001 exhibited more preferable removal of Tl(I)than D-001 and IRC-748,an iminodiacetic chelating polymer,particularly in the presence of competing Ca(II)ions at greater levels in solution.Such preference was ascribed to the Donnan membrane effect caused by D-001 as well as the specific interaction between Tl(I)and HMO.The adsorbed Tl(I)was partially oxidized into insoluble Tl(III)by HMO at acidic pH,while negligible oxidation was observed at circumneutral pH.The exhausted HMO-001 was amenable to efficient regeneration by binary NaOH-NaClO solution for at least 10-cycle batch runs without any significant capacity loss.Fixed-bed column test of Tl(I)-contained industrial effluent and natural water further validated that Tl(I)retention on HMO-001 resulted in a conspicuous concentration drop from 1.3 mg/L to a value lower than 0.14 mg/L(maximum concentration level for industrial effluent regulated by US EPA)and from 1–4?g/L to a value lower than 0.1?g/L(drinking water standard regulated by China Health Ministry),respectively. | PAN BingCai WAN ShunLi ZHANG ShuJuan GUO QingWei XU ZhengCheng LV Lu ZHANG WeiMing | 2014 | Science China Chemistry2014，57，5： | 2 |
| 10 | Factors influencing prehospital delay for patients with acute myocardial infarction显示文摘Objective To investigate the influencing factors for prehospital delay in patients with acute myocardial infarction (AMI). Methods A total of 807 consecutive patients with AMI who presented to the emergency department of Beijing Anzhen Hospital were analyzed. The influence of several potential risk factors on the prehospital delay time (PDT) was evaluated by comparing patients admitted more than 2 hours after onset of chese pain with those admitted within 2 hours after onset. Results Among 807 patients, 402 came to the hospital within 2 hours while the others arrived at the hospital after 2 hours. The median PDT was 130 min. Among the potential variables, advanced age, history of diabetes mellitus, occurrence of symptom at night and use of emergency medical service significantly affected PDT by multivariate analysis. Conclusion Interventions aimed at reducing the prehospital delay in AMI should primarily focus on the awareness of the risk and help-seeking behavior of patients. | Shujuan CHENG Lufen GUO Juyuan LIU Xiaoling ZHU Hongbing YAN | 2007 | Journal of Geriatric Cardiology2007，4，1： | 2 |
| 11 | Research progress on etiology of gestational diabetes mellitus显示文摘As a metabolic disorder during pregnancy,gestational diabetes mellitus (GDM) has an important effects on fetal development,neonatal health and maternal long-term health,and is one of the pregnancy complications with high incidence.It is of great significance that we have an accurate understanding of the etiology and risk factors of GDM for its prevention and control.GDM is a complex disease with multiple etiologies.Current studies have shown that the occurrence of GDM may be the result of combined effect of heredity and environment,but the exact etiology is still unclear.In this paper,we summarized the possible etiologies and risk factors of GDM,so as to understand the occurrence and development of GDM better and to provide possible references for prevention and further etiological studies of GDM. | Jiayue Zhang Shujuan Ma Chuhao Guo Sisi Long Shilan Wu Hongzhuan Tan | 2018 | Global Health Journal2018，2，4： | 2 |
| 12 | A simple identification model for subtle bruises on the fresh jujube based on NIR spectroscopy显示文摘 | Shujuan Zhang Haihong Zhang Yanru Zhao Wei Guo Huamin Zhao | 2013 | 2013 (3-4)2013，，3： | 1 |
| 13 | Force and characteristics of hybrid transducer type ultrasonic motors显示文摘 | Guo Jifeng Gong transfer model shujuan Guo Haixun | 2004 | IEEE Transactions on Ultrasonics Ferroelectrics and Frequency Control2004，51，4： | 1 |
| 14 | PCB Assembly Scheduling with Alternative Nozzle Types for One Component Type显示文摘 | GUO Shujuan TAKAHASHI Katsuhiko MORIKAWA Kat-sumi | | 0，，03： | 1 |
| 15 | Human cytomegalovirus miR-US5-1 inhibits viral replication by targeting Geminin mRNA显示文摘Viruses commonly create favorable cellular conditions for their survival through multiple mechanisms. Micro RNAs(mi RNAs), which function as post-transcriptional regulators, are utilized by human cytomegalovirus(HCMV) in its infection and pathogenesis. In the present study, the DNA replication inhibitor Geminin(GMNN) was identified to be a direct target of hcmv-mi R-US5-1. Overexpression of hcmv-mi R-US5-1 could block the accumulation of GMNN during HCMV infection, and the decrease of GMNN expression caused by hcmv-mi R-US5-1 or GMNN specific si RNA reduced HCMV DNA copies in U373 cells. Meanwhile, ectopic expression of hcmv-mi R-US5-1 and consequent lower expression of GMNN influenced host cell cycle and proliferation. These results imply that hcmv-mi R-US5-1 may affect viral replication and host cellular environment by regulating expression kinetics of GMNN during HCMV infection. | Shujuan Jiang Yujing Huang Ying Qi Rong He Zhongyang Liu Yanping Ma Xin Guo Yaozhong Shao Zhengrong Sun Qiang Ruan | 2017 | Virologica Sinica2017，32，5： | 1 |
| 16 | Shape evolution and magnetic properties of cobalt sulfide 显示文摘 | BAO Shujuan LI Yibin GUO Jun | 2008 | Cryst Growth Des2008，8，： | 1 |
| 17 | Measuring the orbital angular momentum of optical vortices using a multipinhole plate 显示文摘 | Guo Chengshan Yue ShuJuan Wei Gongxing | 2009 | Applied Physics Letters2009，94，23： | 1 |
| 18 | Weight Status and Self-Perception of Weight Among Women of Childbearing Age—China,2015显示文摘Summary What is already known about this topic?Both lean and obese women carry a risk for adverse pregnancy outcomes.Correct self-perception of body weight status is necessary for optimal weight control.What is added by this report?Data from the Nutrition and Chronic Disease Surveillance of Chinese Residents in 2015 were used in this study.The weight status and self-perception of weight among women of childbearing age in China were analyzed to provide basic data for improving the nutritional health of women of childbearing age. | Hongyun Fang Qiya Guo Lahong Ju Shujuan Li Xiaoli Xu Wei Piao Dongmei Yu Liyun Zhao | 2021 | China CDC weekly2021，3，9： | 1 |
| 19 | COLD1 Confers Chilling Tolerance in Rice显示文摘 | Yun Ma Xiaoyan Dai Yunyuan Xu Wei Luo Xiaoming Zheng Dali Zeng Yajun Pan Xiaoli Lin Huanhuan Liu Dajian Zhang Jun Xiao Xiaoyu Guo Shujuan Xu Yuda Niu Jingbo Jin Hui Zhang Xun Xu Legong Li Wen Wang Qian Qian Song Ge Kang Chong | 2015 | Cell2015，，6： | 1 |
| 20 | Astragalus polysaccharide and oxymatrine can synergistically improve the immune efficacy of Newcastle disease vaccine in chicken显示文摘 | Yuku Chen Deyun Wang Yuanliang Hu Zhenhuan Guo Junmin Wang Xiaona Zhao Yunpeng Fan Liwei Guo Shujuan Yang Fuding Sai Yujuan Xing | 2010 | International Journal of Biological Macromolecules2010，，4： | 1 |
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