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| 1 | Nondestructive Testing and Characterization of Residual Stress Field Using an Ultrasonic Method显示文摘To address the difficulty in testing and calibrating the stress gradient in the depth direction of mechanical components, a new technology of nondestructive testing and characterization of the residual stress gradient field by ultrasonic method is proposed based on acoustoelasticity theory. By carrying out theoretical analysis, the sensitivity coefficients of different types of ultrasonic are obtained by taking the low carbon steel(12%C) as a research object. By fixing the interval distance between sending and receiving transducers, the mathematical expressions of the change of stress and the variation of time are established. To design one sending-one receiving and oblique incidence ultrasonic detection probes, according to Snell law, the critically refracted longitudinal wave(LCR wave) is excited at a certain depth of the fixed distance of the tested components. Then, the relationship between the depth of LCR wave detection and the center frequency of the probe in Q235 steel is obtained through experimental study. To detect the stress gradient in the depth direction, a stress gradient LCR wave detection model is established, through which the stress gradient formula is derived by the relationship between center frequency and detecting depth. A C-shaped stress specimen of Q235 steel is designed to conduct stress loading tests, and the stress is measured with the five group probes at different center frequencies. The accuracy of ultrasonic testing is verified by X-ray stress analyzer. The stress value of each specific depth is calculated using the stress gradient formula. Accordingly, the ultrasonic characterization of residual stress field is realized. Characterization results show that the stress gradient distribution is consistent with the simulation in ANSYS. The new technology can be widely applied in the detection of the residual stress gradient field caused by mechanical processing, such as welding and shot peening. | SONG Wentao XU Chunguang PAN Qinxue SONG Jianfeng | 2016 | Chinese Journal of Mechanical Engineering2016，29，2： | 27 |
| 2 | Association of KIR Genotypes and Haplotypes with Susceptibility to Chronic Hepatitis B Virus Infection in Chinese Han Population显示文摘Killer immunoglobulin-like receptor (KIR) genes can regulate the activation of NK and T cells upon interaction with HLA class I molecules. Hepatitis B virus (HBV) infection has been regarded as a multi-factorial disorder disease. Previous studies revealed that KIRs were involved in HCV and HIV infection or clearance. The aim of this study was to explore the possibility of the inheritance of KIR genotypes and haplotypes as a candidate for susceptibility to persistent HBV infection or HBV clearance. The sequence specific primer polymerase chain reaction (SSP-PCR) was employed to identify the KIR genes and pseudogenes in 150 chronic hepatitis B (CHB) patients, 251 spontaneously recovered (SR) controls, and 412 healthy controls. The frequencies of genotype G, M, FZ1 increased in CHB patients compared with healthy control subjects. The frequency of genotype AH was higher in SR controls than that in both CHB patients and healthy controls. The carriage frequencies of genotype G and AH were higher; while, the frequencies of AF and AJ were lower in SR controls than those in healthy control subjects. The frequency of A haplotype was lower, whereas, the frequency of B haplotype was higher in CHB patients and SR controls than those in healthy controls. In healthy controls, haplotype 4 was found lower compared with that in CHB patients and SR controls and the frequency of haplotype 5 was higher in SR controls than that in other two groups. Based on these findings, it seems that the genotypes M and FZ1 are HBV susceptive genotypes; AH, on the other hand, may be protective genotypes that facilitate the clearance of HBV. It appears that the haplotype 4 is HBV susceptive haplotype, whereas, haplotype 5 may be the protective haplotype that facilitates the clearance of HBV. | Zhiming Lu Bingchang Zhang Shijun Chen Zhongtao Gai Zhaolei Feng Xiangdong Liu Yiqing Liu Xin Wen Li Li Yulian Jiao Chunyan Ma Song Shao Xiangfa Cui Guojian Chen Jianfeng Li Yneran Zhao | 2008 | Cellular & Molecular Immunology2008，5，6： | 13 |
| 3 | EFFECTS OF POLISHING PARAMETERS ON MATERIAL REMOVAL FOR CURVED OPTICAL GLASSES IN BONNET POLISHING显示文摘The paper firstly analyzes the influence factor on material removal rate of curved optical work-pieces in the bonnet polishing.Then the experiments are conducted to reveal the effects of several polishing parameters on the material removal rate when the spherical optical glasses are polished with different curvature radius,such as the decrement of the bonnet,the rotational speed of the bonnet and the curvature radius of the work-piece's surface using a bonnet trial-manufacturing machine developed by our assignment groups.In the end,the curvilinear relationships between these parameters and the material removal rate are acquired and the laws of the effects on material removal rate in bonnet polishing by several parameters are given.When the spherical-pieces are polished with smaller curvature radius,it is not proportional to either bonnet decrement or bonnet rotational speed as described by the Preston equation although the removal rate increases as the relative velocity or the applied pressure increases.Therefore,for the purpose of calculating more accurately the material removal of the spherical work-pieces,the Preston equation should be modified and studied further. | SONG Jianfeng YAO Yingxue XIE Dagang GAO Bo YUAN Zhejun | 2008 | Chinese Journal of Mechanical Engineering2008，21，5： | 10 |
| 4 | An novel identification method of the environmental risk sources for surfacewater pollution accidents in chemical industrial parks显示文摘The chemical industry is a major source of various pollution accidents. Improving the management level of risk sources for pollution accidents has become an urgentdemand for most industrialized countries. In pollution accidents, the released chemicals harm the receptors to some extentdepending on their sensitivity or susceptibility. Therefore, identifying the potential risk sources from such a large number of chemical enterprises has become pressingly urgent. Based on the simulation of thewhole accident process, a novel and expandable identification method for risk sources causingwater pollution accidents is presented. The newlydeveloped approach, by analyzing and stimulating thewhole process of a pollution accident between sources and receptors, can be applied to identify risk sources, especially on the nationwide scale. Three major types of losses, such as social, economic and ecological losses,were normalized, analyzed and used for overall consequence modeling. A specific case study area, located in a chemical industry park (CIP) along the Yangtze River in Jiangsu Province, China,was selected to test the potential of the identification method. The results showed that therewere four risk sources for pollution accidents in this CIP. Aniline leakage in the HS Chemical Plantwould lead to the most serious impact on the surroundingwater environment. This potential accidentwould severelydamage the ecosystem up to3.8 kmdownstream of Yangtze River, and lead to pollution over adistance stretching to 73.7 kmdownstream. The proposed method is easily extended to the nationwide identification of potential risk sources. | Jianfeng Peng Yonghui Song Peng Yuan Shuhu Xiao Lu Han | 2013 | Journal of Environmental Sciences2013，25，7： | 9 |
| 5 | A cyclodextrin-based nanoformulation achieves co-delivery of ginsenoside Rg3 and quercetin for chemo-immunotherapy in colorectal cancer显示文摘The immune checkpoint blockade therapy has profoundly revolutionized the field of cancer immunotherapy. However, despite great promise for a variety of cancers, the efficacy of immune checkpoint inhibitors is still low in colorectal cancer(CRC). This is mainly due to the immunosuppressive feature of the tumor microenvironment(TME). Emerging evidence reveals that certain chemotherapeutic drugs induce immunogenic cell death(ICD), demonstrating great potential for remodeling the immunosuppressive TME. In this study, the potential of ginsenoside Rg3(Rg3) as an ICD inducer against CRC cells was confirmed using in vitro and in vivo experimental approaches. The ICD efficacy of Rg3 could be significantly enhanced by quercetin(QTN) that elicited reactive oxygen species(ROS). To amelioratein vivo delivery barriers associated with chemotherapeutic drugs, a folate(FA)-targeted polyethylene glycol(PEG)-modified amphiphilic cyclodextrin nanoparticle(NP) was developed for co-encapsulation of Rg3 and QTN. The resultant nanoformulation(CD-PEG-FA.Rg3.QTN) significantly prolonged blood circulation and enhanced tumor targeting in an orthotopic CRC mouse model, resulting in the conversion of immunosuppressive TME. Furthermore, the CD-PEG-FA.Rg3.QTN achieved significantly longer survival of animals in combination with Anti-PD-L1. The study provides a promising strategy for the treatment of CRC. | Dandan Sun Yifang Zou Liu Song Shulan Han Hao Yang Di Chu Yun Dai Jie Ma Caitriona M.O’Driscoll Zhuo Yu Jianfeng Guo | 2022 | Acta Pharmaceutica Sinica B2022，12，1： | 8 |
| 6 | Design of Quenching Process for Large-sized AISI P20 Steel Block Used as Plastic Die显示文摘与超过 200 公里的厚度为钢块用作塑料的大尺寸的 AISI P20 死,适当熄灭过程是钥匙获得许多厚变硬的层。在这篇论文, AISI P20 钢的不同熄灭过程堵住例如熄灭的油,熄灭的直接的水,与预先凉下来和与预先凉下来熄灭 脾气andself 的水熄灭的水被计算机模拟数字地基于包括热转移,热物理性质,潜热,热转移系数和阶段转变的计算的部分微分方程熄灭进程的数学模型的详细讨论调查,结果证明与预先凉下来和 self-temperingprocess 熄灭的水不能仅仅有效地避免熄灭裂缝,而且更深获得变硬深度比熄灭的油。 | Dongli SONG Jianfeng GU Jiansheng PAN Xin YAO | 2006 | Journal of Materials Science & Technology2006，22，1： | 7 |
| 7 | Overall scheme and on-orbit images of Chang’E-2 lunar satellite CCD stereo camera显示文摘The goals of engineering and scientific missions for Chang’E-2 lunar satellite require high detection sensitivity and large im-aging dynamic range for the onboard CCD cameras.The TDI CCD image sensor was adopted for the two linear CCD stereo cameras for the first time in the lunar reconnaissance of the world.The design argumentation is described in this paper.The analysis shows that the imagers meet the mission requirements.The satellite was launched on 1 October 2010 at zero window.The cameras obtained images of 7 m resolution on the 100 km orbit for the first time on 24 October 2010,and operated once again on 27 October 2010 to take stereo images of the Sinus Iridum with the resolution better than 1.5 m.On the near-moon-arc of 15 km×100 km elliptical orbit,the images are very clear and rich of grey scales,indicating successful com-pletion of the Chang’E-2 engineering mission.At the present the cameras are acquiring the full lunar surface stereo images with 7 m resolution on the 100 km circular orbit to complete their scientific mission. | ZHAO BaoChang YANG JianFeng WEN DeSheng GAO Wei CHANG LingYing SONG ZongXi XUE Bin ZHAO Wei | 2011 | Science China(Technological Sciences)2011，54，9： | 7 |
| 8 | An analytical model for the prediction of cross-section profile and mean roll radius in alloy bar rolling显示文摘In a round-oval-round pass rolling sequence,the cross-section profile of an outgoing workpiece was predicted fast after getting the maximum spread.The concept'critical point on the contact boundary'was proposed and the coordinates of the critical point were solved.The equivalent contact section area was represented and the mean roll radius was determined.The validity of this model was examined by alloy bar rolling experiment and rigid-plastic FEM simulation.Compared with the existing models,the mean roll radius obtained by this model is similar to experiment data. | Yonggang Dong Wenzhi Zhang Jianfeng Song | 2008 | Journal of University of Science and Technology Beijing2008，15，3： | 7 |
| 9 | A Scheme for a Sustainable Urban Water Environmental System During the Urbanization Process in China显示文摘 | Huibin Yu Yonghui Song Xin Chang Hongjie Gao Jianfeng Peng | 2018 | Engineering2018，4，2： | 6 |
| 10 | Determination of full-scale pore size distribution of Gaomiaozi bentonite and its permeability prediction显示文摘Gaomiaozi(GMZ)bentonite is a potential buffer/backfill material for a deep geological disposal of highlevel radioactive waste.It has a wide pore size distribution(PSD)with sizes ranging from several nanometers to more than one hundred microns.Thus,properly characterizing the pore structures of GMZ bentonite is a challenging issue.In this study,pressure-controlled porosimetry(PCP),ratecontrolled porosimetry(RCP),and scanning electron microscopy(SEM)were used to investigate the PSD of GMZ bentonite,The results indicate that each method has its limitation,and a combined use of PCP and RCP is suitable to obtain the full-scale PSD of GMZ bentonite.Moreover,we also compared the full-scale PSD with nuclear magnetic resonance(NMR)result.It is found that there is no significant difference in the range of PSD characterization between NMR and mercury intrusion method(PCP and RCP).However,in a ce rtain range,the detection accuracy of NMR is higher than that of mercury injection method.Finally,permeability prediction based on PCP and SEM data was conducted,and both of the two methods were found to be able to predict the permeability.The combined method is effective to obtain the full-scale PSD of GMZ bentonite,which is the key to estimation of the sealing ability of bentonite buffer. | Jiangfeng Liu Shuaibing Song Xulou Cao Qingbin Meng Hai Pu Yangguang Wang Jianfeng Liu | 2020 | Journal of Rock Mechanics and Geotechnical Engineering2020，12，2： | 5 |
| 11 | Comparison and modeling of two biofilm processes applied to decentralized wastewater treatment显示文摘In order to control water pollution in the rapidly urbanizing South China area,biological contact oxidation(BCO)process and biological aerated filter(BAF)process were applied in a pilot-scale experiment for decentralized wastewater treatment.An investigation to find the optimal parameters of the two biofilm systems was conducted on hydraulic loading,organic loading,and aeration rate.The results indicated that the water reuse criteria required a maximum hydraulic and organic loading of 30.0 m^(3)/(m^(2)·d)and 4.0 kg COD/(m^(3)·d),respectively,as well as a minimum effluent DO of 4.0 mg/L.The utilization of a new media allowed BAF to perform better than BCO.The kinetic description of the COD removal process for BAF and BCO are Se=S0e^(-0.639t)/(1+1.035t),and S_(e)=S_(0)/[(1+0.947t)(1+1.242t)],respectively.The correlativity analysis showed that the two models could predict the effluent water quality based on the hydraulic retention time.Thus,the appropriate hydraulic loading for certain effluent water quality demands could be determined.The two models could be applied to wastewater treatment practice. | Guanglei QIU Liancheng XIANG Yonghui SONG Jianfeng PENG Ping ZENG Peng YUAN | 2009 | Frontiers of Environmental Science & Engineering2009，3，4： | 4 |
| 12 | Phosphate recovery from anaerobic digester effluents using CaMg(OH)_4显示文摘Dolomite lime(DL)(CaMg(OH)_4) was used as an economical source of Mg^(2+)for the removal and recovery of phosphate from an anaerobic digester effluent of a municipal wastewater treatment plant(MWWTP) wastewater. Batch precipitation results determined that phosphate was effectively reduced from 87 to less than 4 mg-P/L when the effluent water was mixed with 0.3 g/L of DL. The competitive precipitation mechanisms of different solids in the treatment system consisting of Ca^(2+)–Mg^(2+)–NH_4^+–PO_4^(3-)CO_3^(2-)were determined by comparing model predictions with experimental results. Thermodynamic model calculations indicated that hydroxyapatite(Ca_(10)(PO_4)_6(OH)_2), Ca_4H(PO_4)_3?3H_2O, Ca_3(PO_4)_2(beta), and Ca_3(PO_4)_2(am2)were more stable than struvite(MgNH_4PO_3?6H_2O) and calcite(CaCO_3). However, X-ray diffraction(XRD) analysis determined the formation of struvite and calcite minerals in the treated effluent. Kinetic experimental results showed that most of the phosphate was removed from synthetic effluent containing NH_4^+within 2 hr, while only 20% of the PO_4^(3-)was removed in the absence of NH_4^+after 24 hr of treatment. The formation of struvite in the DL-treated effluent was due to the rapid precipitation rate of the mineral. The final pH of the DL-treated effluent significantly influenced the mass ratio of struvite to calcite in the precipitates. Because more calcite was formed when the p H increased from 8.4 to 9.6, a p H range of 8.0–8.5 should be used to produce solid with high PO_4^(3-)content. This study demonstrated that DL could be used for effective removal of phosphate from the effluent and that resultant precipitates contained high content of phosphate and ammonium. | Xueyu Liu Zhonghou Xu Jianfeng Peng Yonghui Song Xiaoguang Meng | 2016 | Journal of Environmental Sciences2016，28，6： | 3 |
| 13 | Flexible ITO-free organic solar cells over 10% by employing drop-coated conductive PEDOT:PSS transparent anodes显示文摘Highly conductive poly(3,4-ethylenedioxythiophene):poly(styrene-sulfonic acid)(PEDOT:PSS) has been explored to fabricate flexible and stretchable conductors. Generally, PEDOT:PSS transparent anodes are prepared by spin-coating method. In this article, we adopt a method by dropping PEDOT:PSS aqueous solution on the PET plastic substrate to fabricate flexible electrodes. Compared with spin coating, drop-coating is simple and cost-effective with large-area fabrications. Through this method, we fabricated highly transparent conductive electrodes and systematically studied their electrical, optical, morphological and mechanical properties. With dimethyl sulfoxide/methanesulfonic acid(DMSO/MSA) treated PEDOT:PSS electrode,bendable devices based on non-fullerene system displayed an open-circuit voltage of 0.925 V, a fill factor of 70.74%, and a high power conversion efficiency(PCE) of 10.23% under 100 mW cm^(-2) illumination, which retained over 80% of the initial PCE value after 1000 bending cycles. Based on the findings, drop-coated PEDOT:PSS electrodes exhibited high suitability for the development of large-area and high-efficiency printed solar cell modules in the future. | Huiqin Cui Wei Song Billy Fanady Ruixiang Peng Jianfeng Zhang Jiaming Huang Ziyi Ge | 2019 | Science China Chemistry2019，62，4： | 3 |
| 14 | Effects of Ce,Y,and Sm doping on the thermoelectric properties of Bi_2Te_3 alloy显示文摘Nanopowders of elements doped Bi2Te3thermoelectric alloy R0.2Bi1.8Te3(R Ce,Y and Sm)were synthesized by the hydrothermal method.The nanopowders were hot-pressed into pellets and their thermoelectric properties were investigated.The results show that Ce,Y,and Sm doping has signifcant effects on the morphologies of the synthesized nanopowders and thermoelectric properties.Among the doping elements,Ce doping is a superiority dopant.Although the electrical conductivity and Seebeck coeffcient are not improved much by Ce doping,the thermal conductivity is supressed greatly.As a result the fgure of merit(ZT) of Ce0.2Bi1.8Te3is improved and reaches 1.29 at 398 K,which is higher than the Bi2Te3ingots made by the traditional zone-melting | Fang Wu Hongzhang Song Jianfeng Jia Xing Hu | 2013 | Progress in Natural Science:Materials International2013，23，4： | 3 |
| 15 | Material Removal Model Considering Influence of Curvature Radius in Bonnet Polishing Convex Surface显示文摘The bonnet tool polishing is a novel, advanced and ultra-precise polishing process, by which the freeform surface can be polished. However, during the past few years, not only the key technology of calculating the dwell time and controlling the surface form in the bonnet polishing has been little reported so far, but also little attention has been paid to research the material removal function of the convex surface based on the geometry model considering the influence of the curvature radius. Firstly in this paper, for realizing the control of the freeform surface automatically by the bonnet polishing, on the basis of the simplified geometric model of convex surface, the calculation expression of the polishing contact spot on the convex surface considering the influence of the curvature radius is deduced, and the calculation model of the pressure distribution considering the influence of the curvature radius on the convex surface is derived by the coordinate transformation. Then the velocity distribution model is built in the bonnet polishing the convex surface. On the basis of the above research and the semi-experimental modified Preston equation obtained from the combination method of experimental and theoretical derivation, the material removal model of the convex surface considering the influence of the curvature radius in the bonnet polishing is established. Finally, the validity of the model through the simulation method has been validated. This research presents an effective prediction model and the calculation method of material removal for convex surface in bonnet polishing and prepares for the bonnet polishing the free surface numerically and automatically. | SONG Jianfeng YAO Yingxue | 2015 | Chinese Journal of Mechanical Engineering2015，28，6： | 3 |
| 16 | Overview to the Hard X-ray Modulation Telescope (Insight-HXMT) Satellite显示文摘As China’s first X-ray astronomical satellite, the Hard X-ray Modulation Telescope (HXMT), which was dubbed as Insight-HXMT after the launch on June 15, 2017, is a wide-band(1-250 ke V) slat-collimator-based X-ray astronomy satellite with the capability of all-sky monitoring in 0.2-3 Me V. It was designed to perform pointing, scanning and gamma-ray burst(GRB)observations and, based on the Direct Demodulation Method (DDM), the image of the scanned sky region can be reconstructed.Here we give an overview of the mission and its progresses, including payload, core sciences, ground calibration/facility, ground segment, data archive, software, in-orbit performance, calibration, background model, observations and some preliminary results. | Shuang-Nan Zhang TiPei Li FangJun Lu LiMing Song YuPeng X u CongZhan Liu Yong Chen XueLei Cao QingCui Bu Zhi Chang Gang Chen Li Chen TianXiang Chen YiBao Chen YuPeng Chen Wei Cui WeiWei Cui JingKang Deng YongWei Dong Yuan Yuan Du MinXue Fu GuanHua Gao He Gao Min Gao MingYu Ge YuDong Gu Ju Guan Can Gungor ChengCheng Guo DaWei Han Wei Hu Yue Huang Jia Huo ShuMei Jia LuHua Jiang WeiChun Jiang Jing Jin YongJie Jin Bing Li ChengKui Li Gang Li MaoShun Li Wei Li Xian Li XiaoBo Li XuFang Li YanGuo Li ZiJian Li ZhengWei Li XiaoHua Liang JinYuan Liao GuoQing Liu HongWei Liu ShaoZhen Liu XiaoJing Liu Yuan Liu YiNong Liu Bo Lu XueFeng Lu Tao Luo Xiang Ma Bin Meng Yi Nang JianYin Nie Ge Ou JinLu Qu Na Sai RenCheng Shang GuoHong Shen Liang Sun Ying Tan Lian Tao YouLi Tuo Chen Wang ChunQin Wang GuoFeng Wang HuanYu Wang Juan Wang WenShuai Wang YuSa Wang XiangYang Wen BaiYang Wu BoBing Wu Mei Wu GuangCheng Xiao ShaoLin Xiong LinLi Yan JiaWei Yang Sheng Yang YanJi Yang QiBin Yi Bin Yuan AiMei Zhang ChunLei Zhang ChengMo Zhang Fan Zhang HongMei Zhang Juan Zhang Qiang Zhang ShenYi Zhangs Shu Zhang Tong Zhang WanChang Zhang Wei Zhang WenZhao Zhang Yi Zhang YiFei Zhang YongJie Zhang Yue Zhang Zhao Zhang Zhi Zhang ZiLiang Zhang HaiSheng Zhao XiaoFan Zhao ShiJie Zheng JianFeng Zhou YuXuan Zhu Yue Zhu RenLin Zhuang | 2020 | Science China(Physics,Mechanics & Astronomy)2020，63，4： | 2 |
| 17 | Strain rate sensitivity of tensile properties in high Nb containing TiAl alloys显示文摘The effect of strain rate on the yield strength of high Nb containing TiAl alloy was studied. The results show that the strain rate sensitivity varies with the test temperature, and the yield strength is not sensitive to the strain rate at room temperature but sig- nificantly sensitive to the strain rate at high temperature. An increase of the strain rate or a decrease of the temperature results in an obvious change of fracture mode. It is found that the strain rate sensitivity of this alloy varying with temperature is due to the dislo- cation climb generated at high temperature. | Jianfeng Gao Xiangjun Xu Junpin Lin Xiping Song Yanli Wang Guoliang Chen | 2005 | Journal of University of Science and Technology Beijing2005，12，6： | 2 |
| 18 | Bcl-2 gene and its family genes Bax,Bcl-Xl as well as Fas/Apo-1 and their clinical significance in acute leukemia显示文摘Bcl2geneislocatedonhumanchromosome18q21andconsistsof270Kb.Itisanimportantgenewhichcansupprescelularapoptosis.ApartfromBcl2... | Chen Yan , Zhou Jianfeng , Yue Beibei , Xiang Zhifu , Song Xiaohua Li Chongyu and Wang Bianming | 1998 | Chinese Medical Journal1998，，8： | 2 |
| 19 | Association between diacylglycerol kinase kappa variants and hypospadias susceptibility in a Han Chinese population显示文摘以前的染色体宽的协会研究在基因在欧洲降下的人口与 hypospadias 联系了的 diacylglycerol kinase kappa (DGKK ) 识别了变体。然而, DGKK 的变体都没被证实在一张最近的汉中国学习人口与 hypospadias 被联系,由于在分析包括的单个核苷酸的多型性(SNP ) 的有限数字可能。在这研究,我们试图探讨不一致的结果并且通过 DGKK 变体的更全面的分析在汉中国人口评估在 DGKK 和 hypospadias 之间的协会。我们在 322 个盒子之中与 hypospadias DGKK 为 17 SNP 进行了协会分析在或下游地(58 温和, 113 节制, 128 严重,并且 23 未知) 并且 1008 控制。在 DGKK 的五 SNP (rs2211122, rs4554617, rs7058226, rs7063116,和 rs5915254 ) 显著地与 hypospadias 被联系(P < 0.05 ) ,与 1.64-1.76 的机会比率(ORs ) 。当仅仅温和、中等的盒子与控制相比时,在 DGKK 的 10 SNP 是重要的(P < 0.05 ) ,与 1.56-2.13 的 ORs。当仅仅严重的盒子与控制相比时,没有重要 SNP 被观察。这研究成功地含有在 hypospadias 的 DGKK 变体在一张汉中国人口之中冒险,特别为温和 / 中等的盒子。hypospadias 的严重形式由于另外的基因因素是可能的。 | Hua Xie Xiao-Ling Lin Song Zhang Ling Yu Xiao-Xi Li Yi-Chen Huang Yi-Qing Lyu Hai-Tao Chen Jianfeng Xu Fang Chen | 2018 | Asian Journal of Andrology2018，20，1： | 2 |
| 20 | Crucial control measures to contain China's first Delta variant outbreak显示文摘The SARS-C oV-2 B.1.617.2(Delta) variant flared up in late May in Guangzhou,China.Transmission characteristics of Delta variant were analysed for 153 confirmed cases and two complete transmission chains with seven generations were fully presented.A rapid transmission occurred in five generations within10 days.The basic reproduction number(R_0) was 3.60(95% confidence interval:2.50-5.30).After redefining the concept of close contact,the proportion of confirmed cases discovered from close contacts increased from 43% to 100%.With the usage of a yellow health code,the potential exposed individuals were self-motivated to take a nucleic acid test and regained public access with a negative testing result.Facing the massive requirement of screening,novel facilities like makeshift inflatable laboratories were promptly set up as a vital supplement and 17 cases were found,with 1 pre-symptomatic.The dynamic adjustment of these three interventions resulted in the decline of Rt from 5.00 to 1.00 within 9 days.By breaking the transmission chain and eliminating the transmission source through extending the scope of the close-contact tracing,health-code usage and mass testing,the Guangzhou D elta epidemic was effectively contained. | Lei Luo Zifeng Yang Jingyi Liang Yu Ma Hui Wang Chitin Hon Mei Jiang Zhengshi Lin Wenda Guan Zhitong Mai Yongming Li Kailin Mai Zhiqi Zeng Chuanmeizi Tu Jian Song Bin Liu Yong Liu Jianfeng He Huiyuan Li Bosheng Li Hang Dong Yutian Miao Shujun Fan Lirui Fan Xingyi Liang Ke Li Chun Chen Huihong Deng Zhicong Yang Nanshan Zhong | 2022 | National Science Review2022，9，4： | 2 |
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