维普中文期刊产品整合服务
17篇 您的检索式:作者名="Sun Xiaodi"
    题名 作者 年代 出处 被引量
1DDIT4 promotes gastric cancer proliferation and tumorigenesis through the p53 and MAPK pathways显示文摘Background:Gastric cancer(GC)is one of the most common malignancies worldwide,particularly in China.DNA damage-inducible transcript 4(DDIT4)is a mammalian target of rapamycin inhibitor and is induced by various cellular stresses;however,its critical role in GC remains poorly understood.The present study aimed to investigate the poten-tial relationship and the underlying mechanism between DDIT4 and GC development.Methods:We used western blotting,real-time polymerase chain reaction,and immunohistochemical or immunoflu-orescence to determine DDIT4 expression in GC cells and tissues.High-content screening,cell counting kit-8 assays,colony formation,and in vivo tumorigenesis assays were performed to evaluate cell proliferation.Flow cytometry was used to investigate cell apoptosis and cell cycle distribution.Results:DDIT4 was upregulated in GC cells and tissue.Furthermore,downregulating DDIT4 in GC cells inhibited proliferation both in vitro and in vivo and increased 5-fluorouracil-induced apoptosis and cell cycle arrest.In contrast,ectopic expression of DDIT4 in normal gastric epithelial cells promoted proliferation and attenuated chemosensitivity.Further analysis indicated that the mitogen-activated protein kinase and p53 signaling pathways were involved in the suppression of proliferation,and increased chemosensitivity upon DDIT4 downregulation.Conclusion:DDIT4 promotes GC proliferation and tumorigenesis,providing new insights into the role of DDIT4 in the tumorigenesis of human GC.Feng Du Lina Sun Yi Chu Tingyu Li Chao Lei Xin Wang Mingzuo Jiang Yali Min Yuanyuan Lu Xiaodi Zhao Yongzhan Nie Daiming Fan 2018Cancer Communications2018,38,1:10
2Sedimentary Characteristics of the Cretaceous in the Songliao Basin显示文摘The rupture of the lithosphere in Late Jurassic brought about the eruption of basaltic magma in the Songliao Basin. The evolution of the basin in Cretaceous progressed through six stages: pre-rift doming, extensional fracturing, fault subsidence, fault downwarping, downwarping and shringkage, resulting in the deposition of terrstrial facies nearly 10,000 m thick. There are different depositional sequences in these stages: the depositional period of the Early Cretaceous Shahezi and Yincheng Formations is the development stage of the down-faulted basin, forming a volcanic rock-alluvial fan-fan delta-lacustrine (intercalated with episodic turbidites)-swamp facies sequences; the period of the Early Cretaceous Dengluku Formation is the transformation stage of fault subsidence into fault downwarping of the basin, forming a sequence mainly of alluvial plain-lacustrine facies; the depositional period of the Early Cretaceous Quantou Formation-Late Cretaceous Nenjiang Formation is the downwarping stage of the basin, forming an alluvial plain-delta-lacustrine facies sequence; the period of the Late Cretaceous Sifangtai Formation-Mingshui Formation is the shringkage stage of the basin, forming again a sequence mainly of alluvial plain-alluvial fan and small relict lacustrine facies. These vertical depositional sequences fully display the sedimentary characteristics of a failed continental rift basin. Many facts indicate that the two large-scale lake invasions, synchronous with the global rise of sea level, which took place in the downwarping stage of the basin development, led to the connection between the lake and sea.Liu Zhaojun, Wang Dongpo, Liu Li, Liu Wanzhu, Wang Pujun, Du Xiaodi and Yang Guang Changchun University of Earth Sciences, Changchun, Jilin Sun Sheping 1993Acta Geologica Sinica(English Edition)1993,67,2:7
3The RppC-AvrRppC NLR-effector interaction mediates the resistance to southern corn rust in maize显示文摘Southern corn rust(SCR),caused by the fungal pathogen Puccinia polysora,is a major threat to maize pro-duction worldwide.Efficient breeding and deployment of resistant hybrids are key to achieving durable control of SCR.Here,we report the molecular cloning and characterization of RppC,which encodes an NLR-type immune receptor and is responsible for a major SCR resistance quantitative trait locus.Further-more,we identified the corresponding avirulence effector,AvrRppC,which is secreted by P.polysora and triggers RppC-mediated resistance.Allelic variation of AvrRppC directly determines the effectiveness of RppC-mediated resistance,indicating that monitoring of AvrRppC variants in the field can guide the rational deployment of RppC-containing hybrids in maize production.Currently,RppC is the most frequently deployed SCR resistance gene in China,and a better understanding of its mode of action is crit-ical for extending its durability.Ce Deng April Leonard James Cahill Meng Lv Yurong Li Shawn Thatcher Xueying Li Xiaodi Zhao Wenjie Du Zheng Li Huimin Li Victor Llaca Kevin Fengler Lisa Marshall Charlotte Harris Girma Tabor Zhimin Li Zhiqiang Tian Qinghua Yang Yanhui Chen Jihua Tang Xintao Wang Junjie Hao Jianbing Yan Zhibing Lai Xiaohong Fei Weibin Song Jinsheng Lai Xuecai Zhang Guoping Shu Yibo Wang Yuxiao Chang Weiling Zhu Wei Xiong Juan Sun Bailin Li Junqiang Ding 2022Molecular Plant2022,15,5:6
4Application of a screw conveyor with axial tilt blades on a shearer drum and investigation of conveying performance based on DEM显示文摘Screw conveyors are widely employed in industrial fields for conveying bulk materials.The shearer drum which uses the screw conveying principle is responsible for excavation and conveying coal particles onto the chain conveyor.Screw conveyor performance is affected by potential factors,such as the blade axial tilt angle and style,core shaft form and diameter.The effect of blade axial tilt angle on the conveying performance was investigated with the help of DEM.In the case of the screw conveyor,the mass flow rate,and particle axial velocity increased with increasing positive axial tilt angle,and declined with increasing negative axial tilt angle.In the case of the drum,the mass flow rate,particle axial velocity,and loading rate first increased and then decreased with increasing positive axial tilt angle,and decreased with increasing negative axial tilt angle.These results can be considered as a benchmark for screw conveyor and drum structural designs with axial tilt screw blades.Liqing Sun Xiaodi Zhang Qingliang Zeng Kuidong Gao Kao Jiang Jiawei Zhou 2022Particuology2022,20,2:3
5Establishing an experimental model of photodynamic induced anterior ischemic optic neuropathy显示文摘BACKGROUND: Scholars have supposed to establish animal models of optic neuropathy by pressing and partially amputating optic nerve, increasing intraocular pressure and injecting vasoconstrictor, etc., but the models are greatly different from anterior ischemia optic neuropathy. Therefore, a more ideal method is needed to establish animal model of anterior ischemic optic neuropathy (AION).OBJECTIVE: To establish AION models in rats, observe the functional changes of fundus, fundus fluorescein angiography (FFA), optical coherence tomography (OCT), flash visual evoked potential (F-VEP), and histopathologically confirm its reliability.DESIGN: A randomized control trial.SETTINGS: Department of Ophthalmology, Xi’an Fourth Hospital; Xi’an Institute of Ocular Fundus Diseases.MATERIALS: The experiments were carried out in the research room of Xi’an Institute of Ocular Fundus Diseases from February 2005 to May 2006. Thirty healthy male SD rats of 4-5 weeks old, weighing 140-160 g, were provided by the animal experimental center of the Fourth Military Medical University of Chinese PLA [SCXK(Military)2002-005], and those without eye disease examined by slit lamp and direct ophthalmoscope after mydriasis were enrolled. The conditions for feeding mice without special pathogen were strictly followed. The rats were randomly divided into blank control group (n =5), laser group (n =5), hematoporphyrin derivative (HPD) group and AION group (n =15), each group was numbered randomly. For each rat, the right eye was taken as the experimental eye, and the left one as the control one.METHODS: In the AION group, the rats were injected with HPD (10 mg/kg) via caudal vein, and then the optic discs were exposed to krypton red (647 nm, 80 mV) for 120 s, and the rats were in avoidance of light for 2 weeks postoperatively. Rats in the laser group were only exposed to krypton red (647 nm, 80 mV) for 120 s, and in avoidance of light for 2 weeks postoperatively; Those in the HPD group were only injected with HPD (10 mg/kg) via caudal vein; Those in the blank control group were untouched. ① Visual electrophysiological test: The F-VEP was used to evaluate the function of visual nerve. ② FFA: After mydriasis and anesthesia as describe above, the fluorescein sodium parenteral solution (1 mL/kg) was injected via caudal vein and finished within about 3 s, the time of FFA was recorded from the beginning of injection, the video sight aimed at the optic disc and the surrounding area. ③ After mydriasis and anesthesia as describe above, the rats were examined with OCT. ④ Histological observation: After hematoxylin and eosin (HE) staining, the optic disc and surrounding blood vessels of retina were observed under light microscope at high power field. MAIN OUTCOME MEASURES: The results of fundus, FFA, visual electrophysiological test and OCT detection within 90 days after model establishment were observed. RESULTS: Of the 30 rats, 1 died after anesthesia in the laser group and 2 died in the AION group respectively, and finally 27 rats were involved in the analysis of results. ① Changes in fundus: In the AION group, there was edema in upper optic disc and unclear boundary at 1 day after establishment, edema still could be observed at 6 days, and upper optic disc atrophied and appeared as pale at 90 days. ② FFA results: In the AION group, early 'low fluorescence', middle and late 'high fluorescence' were observed in upper optic disc 1 day after model establishment, and there was 'low fluorescence' at 6 days, and the low fluorescence could be observed all the time at 23 days. ③ Visual electrophysiological changes: In the AION group as compared with the control eyes, the experimental ones had prolonged F-VEP P100 latency [(71.65±8.81), (57.58±8.38) ms, t =3.148, P =0.012], and decreased wave amplitude [(4.77±1.90), (10.06±3.66) μV, t =4.082, P =0.003], and these changes lasted to 35 days after model establishment. ④ OCT results: In the AION group, the reflection surface of part nerve fiber layer was higher than the retina plane, the surface was rough and the thickness was increased at 6 days after model establishment. ⑤ Histopathological results: At 1 day after model establishment, part optic discs had highly edema, edema of nerve fibers, and loose tissue, also accompanied by the displacement of surrounding retina; At 23 days, the optic disc and surrounding nerve fiber layers became thinner, and the numbers of ganglion nuclei in the retina tissue sections were obviously decreased. These changes were not observed in the laser group, HPD group and blank control group. CONCLUSION: The changes of fundus, FFA, OCT, visual electrophysiology and histopathology confirmed that the krypton red laser irradiation (647 nm) at 2 hours after HPD was injected via caudal vein can establish more ideal animal models of AION.Runsheng Wang Xiaodi Wang Peilin Lue Jianwei Bai Jianzhou Wang Xiaoqin Lei Xiao- liang Zhou Hongfen Sun Aizhu Pan 2006Neural Regeneration Research2006,1,4:3
6Pathological and physiological functional cross-talks ofα-synuclein and tau in the central nervous system显示文摘α-Synuclein and tau are abundant multifunctional brain proteins that are mainly expressed in the presynaptic and axonal compartments of neurons,respectively.Previous works have revealed that intracellular deposition ofα-synuclein and/or tau causes many neurodegenerative disorders,including Alzheimer’s disease and Parkinson’s disease.Despite intense investigation,the normal physiological functions and roles ofα-synuclein and tau are still unclear,owing to the fact that mice with knockout of either of these proteins do not present apparent phenotypes.Interestingly,the co-occurrence ofα-synuclein and tau aggregates was found in post-mortem brains with synucleinopathies and tauopathies,some of which share similarities in clinical manifestations.Furthermore,the direct interaction ofα-synuclein with tau is considered to promote the fibrillization of each of the proteins in vitro and in vivo.On the other hand,our recent findings have revealed thatα-synuclein and tau are cooperatively involved in brain development in a stage-dependent manner.These findings indicate strong cross-talk between the two proteins in physiology and pathology.In this review,we provide a summary of the recent findings on the functional roles ofα-synuclein and tau in the physiological conditions and pathogenesis of neurodegenerative diseases.A deep understanding of the interplay betweenα-synuclein and tau in physiological and pathological conditions might provide novel targets for clinical diagnosis and therapeutic strategies to treat neurodegenerative diseases.Mingyue Jin Shengming Wang Xiaodie Gao Zhenyou Zou Shinji Hirotsune Liyuan Sun 2024Neural Regeneration Research2024,19,4:1
7DDIT4通过p53和MAPK通路促进胃癌增殖和肿瘤发生显示文摘背景与目的胃癌(gastric cancer,GC)是世界上最常见的恶性肿瘤之一,在我国尤为常见。DNA损伤诱导转录因子4(DNAdamage-inducibletranscript4,DDIT4)是哺乳动物雷帕霉素靶蛋白抑制因子,由多种细胞应激诱导产生;然而,它在胃癌中的关键作用仍然未知。本研究旨在探讨DDIT4与胃癌发展的关系及其作用机制。方法我们采用蛋白免疫印迹法、实时聚合酶链反应、免疫组化或免疫荧光法检测DDIT4在胃癌细胞和组织中的表达情况。采用高通量筛选、细胞计数试剂盒-8、克隆形成和体内成瘤实验检测细胞增殖情况。采用流式细胞术检测细胞凋亡和细胞周期分布情况。结果 DDIT4在胃癌细胞和组织中表达上调。在胃癌细胞中下调DDIT4表达可抑制体外和体内的细胞增殖并增强了5-氟尿嘧啶诱导的细胞凋亡和细胞周期阻滞。与之相反,在正常胃上皮细胞中DDIT4的异位表达促进了细胞增殖、降低了化疗敏感性。进一步研究表明,丝裂原活化蛋白激酶和p53信号通路参与抑制细胞增殖并在DDIT4下调后增强化疗敏感性。结论 DDIT4促进了胃癌细胞增殖和肿瘤发生,为研究DDIT4在人类胃癌发生、发展中的作用提供了新思路。Feng Du Lina Sun Yi Chu Tingyu Li Chao Lei Xin Wang Mingzuo Jiang Yali Min Yuanyuan Lu Xiaodi Zhao Yongzhan Nie Daiming Fan 2019癌症2019,38,3:1
8Synthesis Methods of Graphdiyne and Graphdiyne Based Materials显示文摘Graphdiyne(GDY),as a new carbon material with two-dimensional structure composed by sp2 and sp carbon atoms,has exhibited excellent properties in various fields due to its conjugated pore structure,high specific surface area and stable structure.Various properties can also be tuned through the adjustability of the electronic structure by chemical methods.This article systematically discusses the preparation methods and strategies of GDY and GDY based materials.These preparation methods provide the way for us to obtain various GDY materials targeting specific research and application.Quanhu Sun Jianjiang He Lei Gao Tiantian Lu Xiaodi Ma Changshui Huang 2022Chinese Journal of Chemistry2022,40,7:1
9Chemical analysis of Astragalus mongholicus polysaccharides and antioxidant activity of the polysaccharides显示文摘Hui Yan Yupeng Xie Shiguang Sun Xiaodi Sun Fengxia Ren Qirong Shi Suhui Wang Weidong Zhang Xiumin Li Jing Zhang 2010Carbohydrate Polymers2010,,3:1
10Anti-ultravioletradiation effects of Cofitis chinensis and PheUodendronamurense glycans by immunomodulating and inhibiting ox-idative injury显示文摘Yan Hui Sun Xiaodi Sun Shiguang 2011International Journal of Biological Mac-romolecules2011,48,:1
11Kinetic and products study of the gas-phase reaction of Lewisite with ozone under atmospheric conditions显示文摘The rate constant for the gas-phase reaction of O_3 and Lewisite was studied in air using the smog chamber technique. The experiments were carried out under pseudo-first-order reaction conditions with [O_3] [Lewisite]. The observed rate constant of O_3 with Lewisite was(7.83 ± 0.38) × 10^(-19)cm^3/(molecule·sec) at 298 ± 2 K. Lewisite was discussed in terms of reactivity with O_3 and its relationship with the ionization potential. Our results show that the rate constant for the gas-phase reaction of O_3 with Lewisite is in line with the trend of the rate constants of O_3 with haloalkenes.Haitao Wang Yuanpeng Zhang Xiaodi Guo Yusheng Shao Runli Gao Dejian Liang Hao Sun 2016Journal of Environmental Sciences2016,28,2:0
12Visible-light deposition of CrO_(x) cocatalyst on TiO_(2):Cr valence regulation for superior photocatalytic CO_(2)reduction to CH_(4)显示文摘Photodeposition is widely adopted for implanting metal/metal oxide cocatalysts on semiconductors.However,it is prerequisite that the photon energy should be sufficient to excite the host semiconductor.Here,we report a lower-energy irradiation powered deposition strategy for implanting CrO_(x) cocatalyst on TiO_(2).Excitingly,CrO_(x)-400 implanted under visible-light irradiation significantly promotes the CH4 evolution rate on TiO_(2)to 8.4μmolg·^(-1)h^(-1) with selectivity of98%from photocatalytic CO_(2)reduction,which is 15 times of that on CrO_(x)-200 implanted under UV-visible-light irradiation.Moreover,CrO_(x)-400 is identified to be composed of higher valence Cr species compared to CrO_(x)-200.This valence states regulation of Cr species is indicated to provide more active sites for CO_(2) adsorption/activation and to modulate the reaction mechanism from single Cr site to Cr-Cr dual sites,thus endowing the superior CH_(4)production.This work demonstrates an alternative strategy for constructing efficient metal oxides cocatalysts on wide bandgap semiconductor.Jingjing Dong Yuan Kong Heng Cao Zhiyu Wang Zhirong Zhang Lidong Zhang Song Sun Chen Gao Xiaodi Zhu Jun Bao 2022Journal of Energy Chemistry2022,31,1:0
13Intramolecular Hydrogen Bond Improved Durability and Kinetics for Zinc‑Organic Batteries显示文摘Organic compounds have the advantages of green sustainability and high designability,but their high solubility leads to poor durability of zinc-organic batteries.Herein,a high-performance quinone-based polymer(H-PNADBQ)material is designed by introducing an intramolecular hydrogen bonding(HB)strategy.The intramolecular HB(C=O⋯N-H)is formed in the reaction of 1,4-benzoquinone and 1,5-naphthalene diamine,which efficiently reduces the H-PNADBQ solubility and enhances its charge transfer in theory.In situ ultraviolet-visible analysis further reveals the insolubility of H-PNADBQ during the electrochemical cycles,enabling high durability at different current densities.Specifically,the H-PNADBQ electrode with high loading(10 mg cm^(-2))performs a long cycling life at 125 mA g^(-1)(>290 cycles).The H-PNADBQ also shows high rate capability(137.1 mAh g^(−1)at 25 A g^(−1))due to significantly improved kinetics inducted by intramolecular HB.This work provides an efficient approach toward insoluble organic electrode materials.Tianjiang Sun Jun Pan Weijia Zhang Xiaodi Jiang Min Cheng Zhengtai Zha Hong Jin Fan Zhanliang Tao 2024Nano-Micro Letters2024,16,3:0
14Molecular basis for the inhibition of β-hydroxyacyI-ACP dehydratase HadAB complex from Mycobacterium tuberculosis by flavonoid inhibitors显示文摘Yu Dong Xiaodi Qiu Neil Shaw Yueyang Xu Yuna Sun Xuemei Li Jun Li Zihe Rao 2015Protein & Cell2015,6,7:0
15Efficacy and safety of systematic corticosteroids among severe COVID-19 patients:a systematic review and meta-analysis of randomized controlled trials显示文摘The benefits and harms of corticosteroids for patients with severe coronavirus disease 2019(COVID-19)remain unclear.We systematically searched PubMed,Embase,and Cochrane Central Register of Controlled Trials from December 31,2019 to October 1,2020 to identify randomized controlled trials(RCTs)that evaluated corticosteroids in severe COVID-19 patients.The primary outcome was all-cause mortality at the longest follow-up.Secondary outcomes included a composite disease progression(progression to intubation,ventilation,extracorporeal membrane oxygenation,ICU transfer,or death among those not ventilated at enrollment)and incidence of serious adverse events.A random-effects model was applied to calculate risk ratio(RR)with 95%confidence intervals(Cis).We used the Grading of Recommendations Assessment,Development,and Evaluation approach to evaluate the certainty of the evidence.Seven RCTs involving 6250 patients were included,of which the Randomized Evaluation of COVID-19 Therapy(RECOVERY)trial comprised nearly 78%of all included subjects.Results showed that corticosteroids were associated with a decreased all-cause mortality(27.3 vs.31.1%;RR:0.85;95%CI:0.73-0.99;P=0.04;low-certainty evidence).Trial sequential analysis suggested that more trials were still required to confirm the results.However,such survival benefit was absent if RECOVERY trial was excluded(RR:0.83;95%CI:0.65-1.06;P=0.13).Furthermore,corticosteroids decreased the occurrence of composite disease progression(30.6 vs.33.3%;RR:0.77;95%CI:0.64-0.92;P=0.005),but not increased the incidence of serious'adverse events(3.5 vs.3.4%;RR:1.16;95%CI:0.39-3.43;P=0.79).Shaolei Ma Changsheng Xu Shijiang Liu Xiaodi Sun Renqi Li Mingjie Mao Shanwu Feng Xian Wang 2021Signal Transduction and Targeted Therapy2021,6,3:0
16Upregulated IRF9 promotes cell apoptosis of hyperlipidemia acute pancreatitis with heart injury by regulating SIRT1显示文摘Hyperlipidemia acute pancreatitis(HLAP)is a significant cause of AP,characterized by recurrent attacks,more complications and high incidence and mortality.HLAP is often accompanied by single or multiple organ damage.Negative regulation of interferon-regulatory factor 9(IRF9)on sirtuin-1(SIRT1)contributes to a range of diseases.However,the function of IRF9 and SIRT1,and the relationship of the two in HLAP with heart injury remain to be illustrated so far.Animal models of HLAP were set up by feeding with high-fat chow and subsequently injecting 20%L-arginine intraperitoneally.The degree of pancreas and heart tissue injury was evaluated.Heart cell apoptosis was assayed by the TUNEL technique.IRF9,SIRT1,p53 and acetylated p53(Ac-p53)expression levels were measured by qRT-PCR and western blot.The correlation between SIRT1 and IRF9 expression levels was analyzed.Results showed that the damage degree in rat pancreas and heart tissues of AP and HLAP group was more distinctly and heart cell apoptosis was elevated.Pancreas,heart injury and cell apoptosis of the HLAP group were more remarkable than that of the AP group.Apparent increases of IRF9 and Ac-p53/p53 expression and a marked drop of SIRT1 expression were observed in the AP and HLAP group rather than NC and HLNC group.IRF9 and Ac-p53/p53 expression levels of the HLAP group were markedly raised compared with the AP group.SIRT1 expression of the HLAP group was obviously lower than that of the AP group.There was an inverse correlation between the decrease of SIRT1 and the increase of IRF9 in AP and HLAP groups.Based on the above findings,we drew a conclusion that in pancreatitis with heart injury,upregulated IRF9 inhibited SIRT1 expression,elevated the acetylation of p53,and increased myocardial cell apoptosis.Hyperlipidemia further exacerbated pancreas and heart injury and accelerated myocardial cell apoptosis.These results would furnish an experimental and theoretical basis to diagnose and therapy diseases.YUN SUN YI LIU BINHUA XUE XIAODIE WANG WEILI YU 2021BIOCELL2021,45,1:0
17Genetic diversity and population structure of Robinia pseudoacacia from six improved variety bases in China as revealed by simple sequence repeat markers显示文摘Robinia pseudoacacia is an important afforesta-tion tree introduced to China in 1878.In the present study,we examined the genetic diversity among 687 strains rep-resenting four improved varieties and two secondary prov-enances,comprising 641 clones and 46 seedlings.Ninety-one simple sequence repeats(SSRs)were selected through segregation analysis and polymorphism characterization,and all sampled individuals were genotyped using well-characterized SSR markers.After excluding loci with non-neutral equilibrium,missing locus data and null alleles,we used 36 primer pairs to assess the genetic diversity of these germplasm resources,revealing vast genetic differentiation among the samples,with an average of 8.352 alleles per locus and a mean Shannon′s index of 1.302.At the popula-tion level,the partitioning of variability was assessed using analysis of molecular variance,which revealed 93%and 7%variation within and among collection sites,respectively.Four clusters were detected using structure analysis,indi-cating a degree of genetic differentiation among the six populations.Insights into the genetic diversity and structure of R.pseudoacacia provide a theoretical basis for the con-servation,breeding and sustainable development in China.Qi Guo Sen Cao Li Dong Xiuyu Li Jiangtao Zhang Yuanshuai Zhang Zijie Zhang Yuhan Sun Cui Long Yingming Fan Chao Han Peiyao Han Xiaodi Liu Yun Li 2022Journal of Forestry Research2022,33,2:0
返回顶部 每页显示:
共1页 首页 上一页 第1页 下一页 末页 /1 跳转

网站首页 | 关于我们 | 联系我们 | 产品服务 | 客服中心 | 广告服务 | 版权声明 | 网站联盟 | 友情链接 | 售卡网点

版权所有© 渝B2-20050021-1 渝公网安备 50019002500403号 违法和不良信息举报中心

互联网出版许可证 新出网证(渝)字10号 全国400电话 - 免长途话费