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| 1 | Risk Factors for Development of Subaxial Subluxations Following Atlantoaxial Arthrodesis for Atlantoaxial Subluxations in Rheumatoid Arthritis显示文摘 | Ken Ishii Morio Matsumoto Yuichiro Takahashi Eijiro Okada Kota Watanabe Takashi Tsuji Hironari Takaishi Masaya Nakamura Yoshiaki Toyama Kazuhiro Chiba | 2010 | Spine2010，，16： | 1 |
| 2 | Age-Related Changes in Expression of Tissue Inhibitor of Metalloproteinases-3 Associated With Transition From the Notochordal Nucleus Pulposus to the Fibrocartilaginous Nucleus Pulposus in Rabbit Intervertebral Disc显示文摘 | Takashi Tsuji Kazuhiro Chiba Hideaki Imabayashi Yoshinari Fujita Naobumi Hosogane Yasunori Okada Yoshiaki Toyama | 2007 | Spine2007，，8： | 1 |
| 3 | Clinical proteomics identified ATP-dependent RNA helicase DDX39 as a novel biomarker to predict poor prognosis of patients with gastrointestinal stromal tumor显示文摘 | Kazutaka Kikuta Daisuke Kubota Tsuyoshi Saito Hajime Orita Akihiko Yoshida Hitoshi Tsuda Yoshiyuki Suehara Hitoshi Katai Yasuhiro Shimada Yoshiaki Toyama Koichi Sato Takashi Yao Kazuo Kaneko Yasuo Beppu Yasufumi Murakami Akira Kawai Tadashi Kondo | 2011 | Journal of Proteomics2011，，4： | 1 |
| 4 | Impact of Lamina Closure on Long-term Outcomes of Open-Door Laminoplasty in Patients With Cervical Myelopathy: Minimum 5-Year Follow-up Study显示文摘 | Morio Matsumoto Kota Watanabe Naobumi Hosogane Takashi Tsuji Ken Ishii Masaya Nakamura Kazuhiro Chiba Yoshiaki Toyama | 2012 | Spine2012，，15： | 1 |
| 5 | Cytopmtective role of Nrf2/Keapl sys- tem in methylmereury toxicity 显示文摘 | Takashi Toyama Daigo Sumi | 2007 | Biochemical and Biophysical Re- search Communications2007，363，： | 1 |
| 6 | Long-Term Outcomes of Japanese Type 2 Diabetic Patients With Biopsy-Proven Diabetic Nephropathy显示文摘 | Miho Shimizu Kengo Furuichi Tadashi Toyama Shinji Kitajima Akinori Hara Kiyoki Kitagawa Yasunori Iwata Norihiko Sakai Toshinari Takamura Mitsuhiro Yoshimura Hitoshi Yokoyama Shuichi Kaneko Takashi Wada | 2013 | Diabetes Care2013，，11： | 1 |
| 7 | Three cases of pneumatosis intestinalis presenting in autoimmune diseases显示文摘 | Akihiro Sagara Kiyoki Kitagawa Kengo Furuichi Shinji Kitajima Tadashi Toyama Toshiya Okumura Akinori Hara Yoshio Sakai Shuichi Kaneko Takashi Wada | 2012 | Modern Rheumatology2012，，4： | 1 |
| 8 | A New Prognostic System for Hepatocellular Carcinoma Including Recurrent Cases: A Study of 861 Patients in a Single Institution显示文摘 | Takashi Toyama Naoki Hiramatsu Takayuki Yakushijin Tsugiko Oze Fumihiko Nakanishi Masakazu Yasumaru Kiyoshi Mochizuki Tatsuya Kanto Tetsuo Takehara Akinori Kasahara Norio Hayashi | 2008 | Journal of Clinical Gastroenterology2008，，3： | 1 |
| 9 | A New Prognostic System for Hepatocellular Carcinoma Including Recurrent Cases: A Study of 861 Patients in a Single Institution显示文摘 | Takashi Toyama Naoki Hiramatsu Takayuki Yakushijin Tsugiko Oze Fumihiko Nakanishi Masakazu Yasumaru Kiyoshi Mochizuki Tatsuya Kanto Tetsuo Takehara Akinori Kasahara Norio Hayashi | 2008 | Journal of Clinical Gastroenterology2008，，3： | 1 |
| 10 | Robot‐assisted partial nephrectomy: Superiority over laparoscopic partial nephrectomy显示文摘 | Ryoichi Shiroki Naohiko Fukami Kosuke Fukaya Mamoru Kusaka Takahiro Natsume Takashi Ichihara Hiroshi Toyama | 2016 | Int. J. Urol2016，，2： | 1 |
| 11 | Long‐Term Renal Denervation Normalizes Disrupted Blood Pressure Circadian Rhythm and Ameliorates Cardiovascular Injury in a Rat Model of Metabolic Syndrome显示文摘 | Tetsuji Katayama Daisuke Sueta Keiichiro Kataoka Yu Hasegawa Nobutaka Koibuchi Kensuke Toyama Ken Uekawa Ma MingJie Takashi Nakagawa Masanobu Maeda Hisao Ogawa Shokei Kim‐Mitsuyama | 2013 | Journal of the American Heart Association2013，，4： | 1 |
| 12 | MEIS1 and HOXA7 genes in human acute myeloid leukemia显示文摘 | Olubunmi Afonja John E. Smith Jr. Debbie M. Cheng Alec S. Goldenberg Edward Amorosi Takashi Shimamoto Shuji Nakamura Kazuma Ohyashiki Junko Ohyashiki Keisuke Toyama Kenichi Takeshita | 2000 | Leukemia Research2000，，10： | 1 |
| 13 | Long-term prognosis of focal segmental glomerulosclerosis treated with therapeutic low-density lipoprotein-apheresis in patients with severe kidney dysfunction and proteinuria显示文摘Background:The prognosis of focal segmental glomerulosclerosis patients with nephrotic syndrome is estimated to be 10%-20%in 5 years and 30%-50%in 10 years,leading to end-stage kidney disease.The response rate with steroid therapy is 40%-60%.Therapeutic low-density lipoprotein-apheresis(LDL-A)may be effective in patients with steroid resistance.Information regarding the long-term prognosis of patients with focal segmental glomerulosclerosis receiving this therapy is scarce.Methods:We investigated the effectiveness of treatment in 50 patients with primary focal segmental glomerulosclerosis diagnosed between 1961 and 2017 at Kanazawa University Hospital and related facilities.The patients were observed at least 12 months after biopsy or until end-stage kidney disease occurrence or death.Results:LDL-A was performed in four patients who presented with steroidresistant nephrotic syndrome(two patients had concurrent acute renal failure for which hemodialysis was performed).In comparison with 17 patients who did not receive LDL-A after 1989,the LDL-A group had higher urinary protein excretion(13.7 vs.5.2 g/day,P=0.053)and serum creatinine(4.11 vs.1.65 mg/dL)levels at onset,and a numerically higher remission rate(75.0%vs.58.7%)compared with the nonlipoprotein-apheresis group.Conclusion:Therapeutic LDL-A can be performed for critical cases and may improve the remission rate. | Shinji Kitajima Megumi Osima Hisayuki Ogura Shiori Nakagawa Yuta Yamamura Taito Miyake Taro Miyagawa Tadashi Toyama Akinori Hara Norihiko Sakai Miho Shimizu Takashi Wada Yasunori Iwata | 2023 | Rheumatology & Autoimmunity2023，3，1： | 0 |
| 14 | Poorly differentiated endocrine carcinoma of the pancreas responded to gemcitabine:Case report显示文摘Poorly differentiated endocrine carcinoma (PDEC) of the pancreas is a rare and aggressive tumor. First-line treatment is commonly a combination of etoposide and cisplatin, but there is no consensus regarding further treatment recommendations. In this report, we describe a case of pancreatic PDEC treated with gemcitabine as third-line chemotherapy. A 62-year-old man with pancreatic PDEC was administered etoposide plus cisplatin as first-line treatment; he then received irinotecan for tumor relapse. However, because irinotecan induced ileus in this patient, we chose gemcitabine as thirdline chemotherapy. After two cycles of gemcitabine (1000 mg/m2 on days 1, 8 and 15 every 4 wk), a partialtumor response was noted by computed tomography (approximately 68% reduction in tumor size). Our patient survived for 15 mo after diagnosis. This is a rare case of unresectable pancreatic PDEC, which showed a partial response to gemcitabine after the failure of two other regimens. Gemcitabine could be an effective treatment option for pancreatic PDEC that is resistant to other treatments. | Shoichi Nakazuru Toshiyuki Yoshio Shigeki Suemura Mari Itoh Manabu Araki Chiaki Yoshioka Makiyo Ohta Yuka Sueyoshi Takashi Ohta Hiroko Hasegawa Kaori Morita Takashi Toyama Noriyoshi Kuzushita Yoshinori Kodama Masayuki Mano Eiji Mita | 2010 | World Journal of Gastroenterology2010，16，30： | 0 |
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