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| 1 | 2019新型冠状病毒基因组特征和流行病学:病毒起源和受体结合的意义显示文摘研究者对来自9例新型冠状病毒肺炎住院患者的支气管肺泡灌洗液样本和培养的分离株进行了下一代测序。从这些个体中获得了严重急性呼吸综合征-冠状病毒2(severe acute respiratory syndrome-coronavirus 2,SARS-CoV-2)的完整和部分基因组序列。利用Sanger测序连接病毒重叠群以获得全长基因组,cDNA末端快速扩增确定终端区。对这些SARSCoV-2基因组和其他冠状病毒基因组进行了系统进化分析,以确定该病毒的进化史并有助于推断其可能的起源。 | 刘青(译) 刘莉(审校) Lu R Zhao X Li J Niu P Yang B Wu H Wang W Song H Huang B Zhu N Bi Y Ma X Zhan F Wang L Hu T Zhou H Hu Z Zhou W Zhao L Chen J Meng Y Wang J Lin Y Yuan J Xie Z Ma J Liu WJ Wang D Xu W Holmes EC Gao GF Wu G Chen W Shi W Tan W | 2020 | 中华高血压杂志2020，28，3： | 516 |
| 2 | Synthesis and characterization of CNT/Ce-TiO_2 nanocomposite for phenol degradation显示文摘An innovative photocatalyst, Carbon nanotube (CNT) supported Ce-TiO2 nanocomposite was successfully synthesized via modi-fied sol gel method and investigated in a batch reactor for abolition of phenol under UV light spectrum. Characterization of catalyst micro-structure and internal properties were done by means of X-ray diffraction (XRD), Brunauer-Emmett-Teller (BET), scanning electron micros-copy (SEM), transmission electron microscopy (TEM) and UV-vis diffuse reflectance spectra (DRS). Ce doping can inhibit phase transfor-mation from anatase to rutile and eliminate the recombination of electron-hole pairs in the catalyst. The presence of CNT in TiO2 composite can both increase the photoactivity under UV and change surface properties to achieve sensitivity to visible light. The optimum mass ratio of CNT support and cerium (Ce) dopant in TiO2 was the prominent factor to harvest CNT/Ce-TiO2 photocatalyst nanocomposite. The results demonstrated that optimum mass ratio of CNT:TiO2:Ce was 0.02:1.0:0.06, which resulted in the great performance of the photocatalyst to de-grade about 94% of phenol in a 50 mg/L solution in only 3 h. In this paper, dissimilar role of CNT support and Ce dopant in the TiO2 photo-catalysis of phenol was also discussed. | Shaari N Tan S H Mohamed A R | 2012 | Journal of Rare Earths2012，30，7： | 12 |
| 3 | Polymorphisms of MTHFD,plasma homocysteine levels, and risk of gastric cancer in ahigh-risk Chinese population显示文摘Purpose:Accumulative evidence suggests that folate has a protective effect on gastric cancer. The methylenetetrahyd-rofolate dlehydrogenase(MTHFD) plays an important role in folate and homocysteine metabolisms, and polymorphisms of MTHFD may result in disturbance of the folate-mediated homocysteine pathway. The aim of this study is to test the hypothesis that genetic variants of MTHFD and plasma homocysteine levels are associated with risk of gastric cancer and modulated by genotypes of methylenetetrahydrofolate reductase(MTHFR). Experimental Design: We genotyped G1958A and T401C in MTHFD and C677T in MTHFR and detected total plasma homocysteine(tHcy) levels in a case-control study of 589 gastric cancer cases and 635 cancer-free controls in a high-risk Chinese population. Results:The variant genotypes of MTHFD 1958AA and 401CC were associated with a significantly increased risk of gastric canceradjusted odds ratio(OR), 2.05; 95% confidence interval(95% CI),1.34-3.13 for 1958AA; adjusted OR,1.43; 95% CI,1.14-1.80 for 401CC compared with 1958GG/GA and 401TT/TC genotypes, respectively. Both of the effects were more evident in the subjects carrying MTHFR 677CT/TT genotypes. The average tHcy level was significantly higher in gastric cancer cases than in controls(P < 0.01), and the upper quartile of tHcy (> 13.6 mu mol/L) was associated with an 82% significantly increased risk of gastric cancer, compared with the lowest quartile of tHcy(<= 8.0 pmol/L;adjusted OR,1.82; 95% CI,1.20-2.75). Conclusions:The strong associations between MTHFD variants and the plasma tHcy levels and gastric cancer risk suggest, for the first time, a possible gene-environment interaction between genetic variants of folate-metabolizing genes and high tHcy levels in gastric carcinogenesis. | Wang, L. N Ke, Q Chen, W. S Wang, J. M Tan, Y. F Zhou, Y Hua, Z. L Ding, W. L Niu, J. Y Shen, J Zhang, Z. F Wang, X. R Xu, Y. H Shen, H. B Yi Xing | 2007 | 南京医科大学学报(自然科学版)2007，27，7： | 10 |
| 4 | Osteoprotegerin: A Novel Secreted Protein Involved in the Regulation of Bone Density显示文摘 | W.S Simonet D.L Lacey C.R Dunstan M Kelley M.-S Chang R Lüthy H.Q Nguyen S Wooden L Bennett T Boone G Shimamoto M DeRose R Elliott A Colombero H.-L Tan G Trail J Sullivan E Davy N Bucay L Renshaw-Gegg T.M Hughes D Hill W Pattison P Campbell S Sander G Van | 1997 | Cell1997，，2： | 6 |
| 5 | Osteoprotegerin Ligand Is a Cytokine that Regulates Osteoclast Differentiation and Activation显示文摘 | D.L Lacey E Timms H.-L Tan M.J Kelley C.R Dunstan T Burgess R Elliott A Colombero G Elliott S Scully H Hsu J Sullivan N Hawkins E Davy C Capparelli A Eli Y.-X Qian S Kaufman I Sarosi V Shalhoub G Senaldi J Guo J Delaney W.J Boyle | 1998 | Cell1998，，2： | 4 |
| 6 | Transfer of multivariate calibration models: a review 显示文摘 | FEUDALE R N WOODY N A TAN H | 2002 | Chemom Intell Lab Syst2002，64，2： | 1 |
| 7 | Salvialnolic acid A, a new depside from roots of Salvia miltiorrhiza 显示文摘 | Li L N Tan R Chen W M | 1984 | Planta Med1984，50，： | 1 |
| 8 | An SVD-based watermarking scheme for protecting rightful ownership显示文摘 | Liu R Z and Tan T N | 2002 | IEEE Transactions on Multimedia2002，4，1： | 1 |
| 9 | Influ- enza viruses expressing chimeric hemagglutinins: Globu- lar head and stalk domains derived from different sub- types 显示文摘 | Hai R Krammer F Tan G S Pica N Eggink D Maamary J Margine I Albrecht R A Palese P | 2012 | J Virol2012，86，10： | 1 |
| 10 | Fabrication of planar gratings by direct ablation using an ultrashort pulse laser in a common optical path configuration 显示文摘 | VENKATAKRISHNAN K SIVAKUMAR N R TAN B | 2003 | Appl Phys2003，76，2： | 1 |
| 11 | Berberine Interfered with breast cancer cells metabolism, balancing energy homeostasis 显示文摘 | Tan W Li N Tan R | 2014 | Anti- cancer Agents Med Chem2014，15，1： | 1 |
| 12 | Adaptive Rejection Metropolis Sampling within Gibbs Sampling显示文摘 | Gilks W R Best N G Tan K K C | 1995 | Applied Statistics1995，44，4： | 1 |
| 13 | Core-structure-mo- tivated design of a phosphine-catalyzed cy- cloaddition reaction: Enantioselective syntheses of spi- rocyclopenteneoxindoles 显示文摘 | Tan B Candelas N R Barbas C F | 2011 | J Am Chem Soc2011，133，： | 1 |
| 14 | Relationships Between Surface Soil Organic Carbon Pool and Site Variables 显示文摘 | TAN Z X LAL R SMECK N E | 2004 | Geoderma2004，121，34： | 1 |
| 15 | RIG-I-Mediated Antiviral Responses to Single-Stranded RNA Bearing 5-Phosphates显示文摘 | Pichlmair A Schulz O Tan CP Nāslund TL Liljestr(o)m P Weber F C R | | 0，，5801： | 1 |
| 16 | Sensitivity analysis for a new system of generalized nonlinear mixed qua- si-variational inclusions显示文摘 | Agarwal R P Huang N J Tan M Y | 2004 | Appl Math Lett2004，17，： | 1 |
| 17 | Inflammato- ry pseudotumors of the lung: progression from organizing pneumonia to fibrous hstiocytoma or to plasma cell granulo- ma in 32 cases显示文摘 | Matsubara O Tan Liu N S Kenney R M | 1988 | Hum Pathol1988，19，7： | 1 |
| 18 | A wireless,passive sensor for quantifying packaged food quality显示文摘 | TAN E L NG W N SHAO R | 2007 | Sensors2007，7，9： | 1 |
| 19 | Six isoforms of cardiotoxin in Malayan spitting cobra (Naja naja sputatrix) venom:cloning and characterization of cDNAs 显示文摘 | Armugam A Lachumanan R Tan C H Tan N H | 1998 | Biochim Biophys Acta1998，1380，： | 1 |
| 20 | Image contentbased watermarking model显示文摘 | LIU R Z WANG Y H TAN T N | 2001 | Journal of Image and Graphics2001，6，6： | 1 |
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