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| 1 | Chemical characteristics of PM_(2.5) during dust storms and air pollution events in Chengdu,China显示文摘每天好的微粒(PM2.5 ) 样品从 2009 年 4 月在 Chengdu 被收集到 2010 年 2 月在灰尘暴风雨(决策支持系统) 和污染事件的几种类型期间调查他们的化学侧面,包括薄雾(HD ) ,燃烧的生物资源(BB ) ,和焰火显示(FD ) 。最高的 PM2.5 集体集中在决策支持系统(283.3 g/m3 ) 期间被发现,列在后面由 FD (212.7 g/m3 ) , HD (187.3 g/m3 ) ,和 BB (130.1 g/m3 ) 。大多数元素的集中在决策支持系统和污染事件期间被提高,除了 BB。第二等的无机的离子(NO3, SO42,和 NH4+) 在 HD 期间被充实,当从 BB 的 PM2.5 显示出高 K+ 时但是低 SO42。FD 在 SO42 在 K+ 和丰富引起了增加。Ca2+ 充满 DS 样品。离子平衡计算从 HD 显示了那 PM2.5, FD 比在正常的天更酸,但是 DS 和 BB 粒子是碱的。最高器官的碳(OC ) 集中在 FD 期间是 26.1 g/m3,列在后面由 BB (23.6 g/m3 ) , HD (19.6 g/m3 ) ,和决策支持系统(18.8 g/m3 ) 。相反,元素的碳(EC ) 集中比在 BB (6.2 g/m3 ) 和决策支持系统(6.0 g/m3 ) 期间在 HD (10.6 g/m3 ) 和 FD (9.5 g/m3 ) 期间是更丰富的。最高的 OC/EC 比率在 BB 期间被获得,与在 HD 期间最低。SO42/K+ 和 TCA/SO42 比率证明了是为区分污染事件的有效指示物。集体平衡证明那有机物, SO42,和 NO3 在污染事件期间是主导的化学部件,当土壤灰尘在决策支持系统期间是主导的时。 | Qiyuan Wang Junji Cao Zhenxing Shen JunTao Shun Xiao Lei Luo Qingyang He Xinying Tang | 2013 | Particuology2013，11，1： | 23 |
| 2 | YAP promotes osteogenesis and suppresses adipogenic differentiation by regulatingβ-catenin signaling显示文摘YAP(yes-associated protein) is a transcriptional factor that is negatively regulated by Hippo pathway, a conserved pathway for the development and size control of multiple organs. The exact function of YAP in bone homeostasis remains controversial. Here we provide evidence for YAP's function in promoting osteogenesis, suppressing adipogenesis, and thus maintaining bone homeostasis.YAP is selectively expressed in osteoblast(OB)-lineage cells. Conditionally knocking out Yap in the OB lineage in mice reduces cell proliferation and OB differentiation and increases adipocyte formation, resulting in a trabecular bone loss. Mechanistically, YAP interacts with β-catenin and is necessary for maintenance of nuclear β-catenin level and Wnt/β-catenin signaling. Expression of β-catenin in YAP-deficient BMSCs(bone marrow stromal cells) diminishes the osteogenesis deficit. These results thus identify YAP-β-catenin as an important pathway for osteogenesis during adult bone remodeling and uncover a mechanism underlying YAP regulation of bone homeostasis. | Jin-Xiu Pan Lei Xiong Kai Zhao Peng Zeng Bo Wang Fu-Lei Tang Dong Sun Hao-han Guo Xiao Yang Shun Cui Wen-Fang Xia Lin Mei Wen-Cheng Xiong | 2018 | Bone Research2018，6，2： | 19 |
| 3 | Calcium-binding ability of soy protein hydrolysates显示文摘This present study investigated the ability of various soy protein hydrolysates(SPHs)in binding calcium.It was demonstrated that the amount of Ca-bound depended greatly on the SPHs obtained using different proteases,which included:neutrase, flavourzyme,protease M and pepsin.The maximum level of Ca-bound(66.9 mg/g)occurred when protease M was used to hydrolyze soy protein.Peptide fragments exhibiting high Ca-binding capacity had molecular weights of either 14.4 or 8-9 kDa.The level of Ca-bound increased linearly with the increment of carboxyl content in SPHs,and further deamidation on SPHs from protease M improved Ca-binding of the hydrolysate. | Xiao Lan Bao Mei Song Jing Zhang Yang Chen Shun Tang Guo | 2007 | Chinese Chemical Letters2007，18，9： | 14 |
| 4 | Disinfection byproducts in drinking water and regulatory compliance: A critical review显示文摘消毒副产品(DBP ) 在在很多个国家喝水被调整。这批评评论集中于与 DBP 规章的依从联系的问题,包括为 DBP 分析,出现层次,在各种各样的国家之中的规定比较, DBP 依从策略,和新兴的 DBP 的方法。在中国和美国(美国) 之间的规定比较显示在中国的 DBP 规定基于调整混合物和最大的层次的数字是更紧的。用信息收集规则(ICR ) 数据库的比较评价显示 500 大美国的依从率在中国规定下面浇植物在 US 规定下面是比那低得多的(例如 62.2% 对 89.6% 为全部的 trihalomethanes ) 。先锋移动和其他的 disinfectants 是为 DBP 规章的依从的普通惯例。包括为 haloacetic 酸移动为 trihalomethane 移动和 biodegradation 脱衣的空气,在形成以后的 DBP 移动在 DBP 控制获得了更多的接受。包括 iodinated DBP 和含氮的 DBP,新兴的 DBP 的形成是先锋移动和其他的消毒的非计划中的后果之一。然而,在许多底层,比碳的 DBP,新兴的 DBP 提出了更高的健康风险。 | Xiaomao WANG Yuqin MAO Shun TANG Hongwei YANG Yuefeng E XIE | 2015 | Frontiers of Environmental Science & Engineering2015，9，1： | 8 |
| 5 | Intradural spinal seeding and fatal progression of a sacrococcygeal chordoma: a case report显示文摘 | JI Tao GUO Wei SHEN Dan-hua YANG Yi TANG Shun | 2008 | Chinese Medical Journal2008，，12： | 7 |
| 6 | 锂电池资源回收研究进展显示文摘随着新能源汽车的快速普及,我国动力锂电池的数量与日俱增,电池原材料价格的不断上涨以及大量废弃电池对环境影响的压力越来越大,退役动力锂电池的回收也被提上了日程。我国动力锂电池回收产业拥有良好的发展前景,本文综述了退役动力电池正极材料回收工艺,重点介绍了正极材料再生与修复工艺,分析了现有回收体系的不足进行了分析,最后对动力电池回收的发展进行了展望。 | 郭京龙 丁庆 程琦 章明高 曹元成 TANG Shun | 2018 | 功能材料与器件学报2018，24，3： | 4 |
| 7 | Preclinical evaluation and pilot clinical study of [^(18)F]AlF-labeled FAPI-tracer for PET imaging of cancer associated fibroblasts显示文摘In recent years,fibroblast activation protein(FAP)has emerged as an attractive target for the diagnosis and radiotherapy of cancers using FAP-specific radioligands.Herein,we aimed to design a novel^(18)Flabeled FAP tracer([^(18)F]Al F-P-FAPI)for FAP imaging and evaluated its potential for clinical application.The[^(18)F]Al F-P-FAPI novel tracer was prepared in an automated manner within 42 min with a non-decay corrected radiochemical yield of 32±6%(n=8).Among A549-FAP cells,[^(18)F]Al F-P-FAPI demonstrated specific uptake,rapid internalization,and low cellular efflux.Compared to the patent tracer[^(18)F]FAPI-42,[^(18)F]Al F-P-FAPI exhibited lower levels of cellular efflux in the A549-FAP cells and higher stability in vivo.Micro-PET imaging in the A549-FAP tumor model indicated higher specific tumor uptake of[^(18)F]Al F-P-FAPI(7.0±1.0%ID/g)compared to patent tracers[^(18)F]FAPI-42(3.2±0.6%ID/g)and[68 Ga]Ga-FAPI-04(2.7±0.5%ID/g).Furthermore,in an initial diagnostic application in a patient with nasopharyngeal cancer,[^(18)F]Al F-P-FAPI and[^(18)F]FDG PET/CT showed comparable results for both primary tumors and lymph node metastases.These results suggest that[^(18)F]Al F-P-FAPI can be conveniently prepared,with promising characteristics in the preclinical evaluation.The feasibility of FAP imaging was demonstrated using PET studies. | Kongzhen Hu Junqi Li Lijuan Wang Yong Huang Li Li Shimin Ye Yanjiang Han Shun Huang Hubing Wu Jin Su Ganghua Tang | 2022 | Acta Pharmaceutica Sinica B2022，12，2： | 4 |
| 8 | A New Type of Polymer-Supported Metallocene Catalyst for Ethylene Polymerization显示文摘A new polymer-supported metallocene catalyst has been prepared. The polymer- supported metallocene displayed considerably high activity in ethylene polymerization, the highest being 3.62(107gPE/molZr(h, the molecular weight of the polyethylene produced was Mn = 1.29(105, about 3-4 times those of corresponding homogeneous zirconocenes. The polymer- supported metallocene keeps the characteristics of homogeneous metallocene catalysts, and offers some features,such as adaptable to gas phase and slurry processes; easy to prepare in low cost; relatively high activity and lower MAO/Zr ratio; lower inorganic residues in the polyolefins as compared to cases of SiO2, Al2O3 or MgCl2; unitary active structure, no complex surface as with SiO2; good control of morphology of the resulting polymer. | Guang Qian YU*, De Ze ZHANG, Fu SHUN, Li Jun QIAO,Tao TANG, Bao Tong HUANG State Key Laboratory of Polymer Physics and Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences Polymer Chemistry Laboratory, Chemistry Academy of S | 2001 | Chinese Chemical Letters2001，12，3： | 4 |
| 9 | The establishment and evaluation of near infrared universal model to determinate the effective ingredient content in pesticide rapidly显示文摘一个近红外线的通用定量分析模型被建立到确定在杀虫剂 EC (hikernalisation ) 由的有效成分内容请(部分最少的广场) 算法,模型预兆的能力被外部检查方法评估。模型在从五个不同公司,和模型决心系数 R2 和 RMSECV (生气确认的根均方差)包含一样的活跃成分的样品之中被建立分别地,是 0.9997 和 0.0223 在预言的价值和严峻的集合样品的化学价值之间的相对错误在2.71%和3.36%之间,它显示方法到确定在由确定的通用模型的杀虫剂 EC 的有效成分内容能遇见 | Yan Mei Xiong Xiang Zhong Song Chang Zhou Chen Hong Ping Lin Guo Tang Yue Huang Jia Duan Shun Geng Min | 2012 | Chinese Chemical Letters2012，23，9： | 3 |
| 10 | Long-Term Treatment With Entecavir Induces Reversal of Advanced Fibrosis or Cirrhosis in Patients With Chronic Hepatitis B显示文摘 | Eugene R. Schiff Samuel S. Lee You–Chen Chao Seung Kew Yoon Fernando Bessone Shun–Sheng Wu Wieslaw Kryczka Yoav Lurie Adrian Gadano George Kitis Suzanne Beebe Dong Xu Hong Tang Uchenna Iloeje | 2011 | Clinical Gastroenterology and Hepatology2011，，3： | 3 |
| 11 | The MING proposal at SHINE:megahertz cavity enhanced X‑ray generation显示文摘The cavity-based X-ray free-electron laser(XFEL)has promise in producing fully coherent pulses with a bandwidth of a few meV and very stable intensity,whereas the currently existing self-amplified spontaneous emission(SASE)XFEL is capable of generating ultra-short pulses with chaotic spectra.In general,a cavity-based XFEL can provide a spectral brightness three orders of magnitude higher than that of the SASE mode,thereby opening a new door for cutting-edge scientific research.With the development of superconducting MHz repetition-rate XFEL facilities such as FLASH,European-XFEL,LCLS-II,and SHINE,practical cavity-based XFEL operations are becoming increasingly achievable.In this study,megahertz cavity enhanced X-ray generation(MING)is proposed based on China’s first hard XFEL facility-SHINE,which we refer to as MING@SHINE. | Nan‑Shun Huang Zi‑Peng Liu Bang‑Jie Deng Zi‑Han Zhu Shao‑Hua Li Tao Liu Zheng Qi Jia‑Wei Yan Wei Zhang Sheng‑Wang Xiang Yang‑Yang Lei Ya Zhu Yong‑Zhou He Qi‑Bing Yuan Fei Gao Rong‑Bing Deng Sen Sun Zhi‑Di Lei Zhi‑Qiang Jiang Meng‑Qi Duan Yuan Zhuan Xue‑Fang Huang Peng‑Cheng Dong Zhong‑Liang Li Shang‑Yu Si Lian Xue Si Chen Yong‑Fang Liu Ya‑Jun Tong Hai‑Xiao Deng Zhen‑Tang Zhao | 2023 | Nuclear Science and Techniques2023，34，1： | 2 |
| 12 | Biomedical polymers: synthesis, properties, and applications显示文摘Biomedical polymers have been extensively developed for promising applications in a lot of biomedical fields, such as therapeutic medicine delivery, disease detection and diagnosis, biosensing, regenerative medicine, and disease treatment. In this review, we summarize the most recent advances in the synthesis and application of biomedical polymers, and discuss the comprehensive understanding of their property-function relationship for corresponding biomedical applications. In particular, a few burgeoning bioactive polymers, such as peptide/biomembrane/microorganism/cell-based biomedical polymers, are also introduced and highlighted as the emerging biomaterials for cancer precision therapy. Furthermore, the foreseeable challenges and outlook of the development of more efficient, healthier and safer biomedical polymers are discussed. We wish this systemic and comprehensive review on highlighting frontier progress of biomedical polymers could inspire and promote new breakthrough in fundamental research and clinical translation. | Wei-Hai Chen Qi-Wen Chen Qian Chen Chunyan Cui Shun Duan Yongyuan Kang Yang Liu Yun Liu Wali Muhammad Shiqun Shao Chengqiang Tang Jinqiang Wang Lei Wang Meng-Hua Xiong Lichen Yin Kuo Zhang Zhanzhan Zhang Xu Zhen Jun Feng Changyou Gao Zhen Gu Chaoliang He Jian Ji Xiqun Jiang Wenguang Liu Zhuang Liu Huisheng Peng Youqing Shen Linqi Shi Xuemei Sun Hao Wang Jun Wang Haihua Xiao Fu-Jian Xu Zhiyuan Zhong Xian-Zheng Zhang Xuesi Chen | 2022 | Science China Chemistry2022，65，6： | 2 |
| 13 | Preparation of nitrogen doped clews-like carbon materials and their application as the electrode in supercapacitor显示文摘In this work, nitrogen doped clews-like carbon materials were successfully fabricated through hydrothermal polymerization method, followed by post treatment that integrated the carbonization,activation and post-nitrogen doping into one process. This preparation method can form particular hierarchical porous structure without using any sacrificial templates. The experimental results show that the nitrogen doped clews-like hierarchical porous carbon materials possess a relatively high specific surface area of 815 m^2/g with the nitrogen content of 10.58 at%. The electrochemical properties show that the resulting sample delivers 258 F/g at a 0.5 A/g and excellent capacity retention of 79% at 20 A/g. After conducting 10,000 charge-discharge cycles at 10 A/g, the capacitance retention of 98.3% is achieved.These intriguing results demonstrate that the obtained nitrogen doped clews-like carbon materials will be promising electrode materials for supercapacitor and other energy storage devices. | Shengrui Chen Jiyuan Liang Jinxing Zhao Haifeng Li Yan Liu Heming Deng Chang Liu Shun Tang Yuan-Cheng Cao | 2019 | Chinese Chemical Letters2019，30，3： | 2 |
| 14 | Degradation mechanism analysis of LiNi_(0.5)Co_(0.2)Mn_(0.3)O_(2) single crystal cathode materials through machine learning显示文摘LiNi_(0.5)Co_(0.2)Mn_(0.3)O_(2)(NCM523)has become one of the most popular cathode materials for current lithium-ion batteries due to its high-energy density and cost performance.However,the rapid capacity fading of NCM severely hinders its development and applications.Here,the single crystal NCM523 materials under different degradation states are characterized using scanning transmission electron microscopy(STEM).Then we developed a neural network model with a two-sequential attention block to recognize the crystal structure and locate defects in STEM images.The number of point defects in NCM523 is observed to experience a trend of increasing first and then decreasing in the degradation process.The space between the transition metal columns shrinks obviously,inducing dramatic capacity decay.This analysis sheds light on the defect evolution and chemical transformation correlated with layered material degradation.It also provides interesting hints for researchers to regenerate the electrochemical capacity and design better battery materials with longer life. | Wuxin Sha Yaqing Guo Danpeng Cheng Qigao Han Ping Lou Minyuan Guan Shun Tang Xinfang Zhang Songfeng Lu Shijie Cheng Yuan-Cheng Cao | 2022 | npj Computational Materials2022，，1： | 1 |
| 15 | Epidemiological Survey of Hemoglobinopathies Based on Next-Generation Sequencing Platform in Hunan Province,China显示文摘Objective This study was aimed at investigating the carrier rate of,and molecular variation in,α-andβ-globin gene mutations in Hunan Province.Methods We recruited 25,946 individuals attending premarital screening from 42 districts and counties in all 14 cities of Hunan Province.Hematological screening was performed,and molecular parameters were assessed.Results The overall carrier rate of thalassemia was 7.1%,including 4.83%forα-thalassemia,2.15%forβ-thalassemia,and 0.12%for bothα-andβ-thalassemia.The highest carrier rate of thalassemia was in Yongzhou(14.57%).The most abundant genotype ofα-thalassemia andβ-thalassemia was-α^(3.7)/αα(50.23%)andβ^(IVS-Ⅱ-654)/β^(N)(28.23%),respectively.Fourα-globin mutations[CD108(ACC>AAC),CAP+29(G>C),Hb Agrinio and Hb Cervantes]and sixβ-globin mutations[CAP+8(C>T),IVS-Ⅱ-848(C>T),-56(G>C),beta nt-77(G>C),codon 20/21(-TGGA)and Hb Knossos]had not previously been identified in China.Furthermore,this study provides the first report of the carrier rates of abnormal hemoglobin variants andα-globin triplication in Hunan Province,which were 0.49%and 1.99%,respectively.Conclusion Our study demonstrates the high complexity and diversity of thalassemia gene mutations in the Hunan population.The results should facilitate genetic counselling and the prevention of severe thalassemia in this region. | XI Hui LIU Qin XIE Dong Hua ZHOU Xu TANG Wang Lan TANG De Guo ZENG Chun Yan WANG Qiong NIE Xing Hui PENG Jin Ping GAO Xiao Ya WU Hong Liang ZHANG Hao Qing QIU Li FENG Zong Hui WANG Shu Yuan ZHOU Shu Xiang HE Jun ZHOU Shi Hao ZHOU Fa Qun ZHENG Jun Qing WANG Shun Yao CHEN Shi Ping ZHENG Zhi Fen MA Xiao Yuan FANG Jun Qun LIANG Chang Biao WANG Hua | 2023 | Biomedical and Environmental Sciences2023，36，2： | 1 |
| 16 | Application of circular la- ser vision sensor (CLVS) on welded seam tracking显示文摘 | Xu Peiquan Tang Xinhua Yao Shun | 2008 | Journal of Materials Processing Technology2008，24，7： | 1 |
| 17 | Tribological properties of Cu-based composites with S-doped NbSe_2显示文摘n this study, S-doped Nb Se_2(NbS_(0.2)Se_(1.8)) powders were fabricated, and the corresponding Cu-based composites(Cu/Nb S_(0.2)Se_(1.8)) were obtained by powder metallurgy technique. The phase compositions, physical, and tribological properties of Cu-based composites were investigated systematically. The results show that Cu matrix reacts with Nb S_(0.2)Se_(1.8)to produce Cu_2 Se and Cu_(0.38) Nb S_(0.2)Se_(1.8)during sintering process, which influences the physical and tribological properties of Cu-based composites significantly. Specially, with Nb S_(0.2)Se_(1.8)content increasing, the density of Cu/Nb S_(0.2)Se_(1.8)composites decreases, and the hardness increases firstly and then decreases, while the electric resistivity increases slightly. In addition, the incorporation of Nb S_(0.2)Se_(1.8)enhances the tribological properties of Cu greatly, which is attributed to the lubricating effect of Cu_(0.38) Nb S_(0.2)Se_(1.8)and the reinforcement effect of Cu_2 Se. In particular, when the content of Nb S_(0.2)Se_(1.8)is 6 wt%, the Cu-based composite has the best tribological properties. | Bei-Bei Chen Shuai Chen Jin Yang Hong-Ping Li Shun Guo Hua Tang Chang-Sheng Li | 2015 | Rare Metals2015，34，6： | 1 |
| 18 | Characteristics of sputtered Ta-B-N thin films as diffusion barriers between copper and silicon显示文摘 | Lin Shun tang Lee Chiapyng | 2006 | Appl Surf Sei2006，253，3： | 1 |
| 19 | Application of circular la-ser vision sensor ( CLVS) on welded seam tracking 显示文摘 | Xu Peiquan Tang Xinhua Yao Shun | 2008 | Journalof Materials Processing Technology2008，205，13： | 1 |
| 20 | Therblig-based energy supply modeling of computer numerical control machine tools显示文摘 | YU Jingxiang TANG Renzheng JIA Shun | 2014 | Journal of Cleaner Production2014，65，1： | 1 |
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