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| 1 | Effects of field application of phosphate fertilizers on the availability and uptake of lead, zinc and cadmium by cabbage (Brassica chinensis L.) in a mining tailing contaminated soil显示文摘A field trial was conducted to evaluate the reduction of bioavailability of heavy metals including lead (Pb), zinc (Zn) and cadmium (Cd) in a soil contaminated by mining tailings in Shaoxing, Zhejiang, China. Three commercial phosphate (P) fertilizers including phosphate rock (PR), calcium magnesium phosphate (CMP), and single superphosphate (SSP) were applied to the plot at three P application rates, 50, 300, and 500 g/m2 with 9 treatments and control (CK). Plants, water soluble and exchangeable (WE) extraction procedure and modified toxicity characteristic leaching procedure (TCLP) were employed. It was found that the addition of all three P fertilizers significantly decreased WE Pb (22.0%-81.4%), Cd (1.5%-30.7%) and Zn (11.7%-75.3%, exception of SSP treatments with no significant difference) and TCLP Pb concentration (27.1%-71.2%), compared with the control, leading to reduced uptake of Pb (16.0%-58.0%), Cd (16.5%-66.9%) and Zn (1.2%-73.2%) by cabbage (Brassica chinensis L.). It was suggested that P fertilizers induced immobilization of heavy metals such as Pb, Cd, and Zn. CMP provided the most effective method of reducing metal toxicity, mobility, and phytoavailability. At the P application rate of 300 g/m2, CMP would be cost-effective to decrease WE Pb, Zn, and Cd concentration from 666 to 137 mg/kg, from 31.2 to 8.71 mg/kg, and from 1.69 to 1.36 mg/kg, respectively. SSP was more effective in reducing Pb bioavailability than PR but had variable effects on Zn bioavailability. Cd uptake by cabbage was negatively correlated with soil pH rather than with WE or TCLP, indicating that Cd uptake by cabbage was a complex process. It should be careful to evaluate the impact of phosphate application on Cd availability in soil. | Biling WANG Qiufeng SU | 2008 | Journal of Environmental Sciences2008，20，9： | 39 |
| 2 | Deep structure beneath the southwestern section of the Longmenshan fault zone and seimogenetic context of the 4.20 Lushan M_S7.0 earthquake显示文摘Magnetotelluric measurements were carried out along two profiles across the middle and southwestern sections of the Longmenshan fault zone(LMSf)from 2009 to 2011,after the 2008 Wenchuan MW7.9 earthquake.The former profile crosses the Wenchuan event epicenter and the latter one crosses 2013 Lushan MS7.0 event epicenter.The data were analyzed using advanced processing techniques,including phase tensor and two-dimensional inversion methods,in order to obtain reliable 2-D profiles of the electrical structure in the vicinity of the two earthquakes.A comparison of the two profiles indicates both similarities and differences in the deep crustal structure of the LMSf.West of the southwestern section,a crustal high conductivity layer(HCL)is present at about 10 km depth below the Songpan-Garzêblock;this is about 10 km shallower than that under the middle section of the LMSf.A high resistivity body(HRB)is observed beneath the southwestern section,extending from the near surface to the top of upper mantle.It has a smaller size than the HRB observed below the middle section.In the middle section,there is a local area of decreased resistivity within the HRB but there is absence of this area.The 2013 Lushan earthquake occurred close to the eastern boundary of HRB and the Shuangshi-Dachuan fault,of which the seismogenic context has both common and different features in comparison with the 2008 Wenchuan event.On a large scale,the 2013 Lushan earthquake is associated with the HCL and deformation in the crust including HCL of the eastern Tibetan Plateau.In order to assess seismic risk,it is important to consider both the stress state and the detailed crustal structure in different parts of the LMSf. | ZHAN Yan ZHAO GuoZe UNSWORTH Martyn WANG LiFeng CHEN XiaoBin LI Tao XIAO QiBin WANG JiJun TANG Ji CAI JunTao WANG YanZhao | 2013 | Chinese Science Bulletin2013，58，28： | 39 |
| 3 | Conceptualizing and Measuring Economic Resilience of Resource-based Cities: Case Study of Northeast China显示文摘This paper develops a conceptual model and an indicator system for measuring economic resilience of resource-based cities based on the theory of evolutionary resilience and the related concepts of persistence, adaptation, and transformation. Nineteen resource-based cities in Northeast China were analyzed using the indicator system. The results showed that Liaoning and Jilin provinces had higher economic resilience than Heilongjiang Province. Panjin, Benxi, and Anshan in Liaoning Province were the top three cities, while Shuangyashan and other coal-based cities in Heilongjiang Province ranked last. Metals-and petroleum-based cities had significantly higher resilience than coal-based cities. The differences in persistence, adaptability, transformation, and resilience among resource-based cities decreased since the introduction of the Northeast Revitalization Strategy in 2003. Forestry-based cities improved the most in terms of resilience, followed by metals-based and multiple-resource cities; however, resilience dropped for coal-based cities, and petroleum-based cities falling the most. The findings illustrate the importance and the way to develop a differentiated approach to improve resilience among resource-based cities. | TAN Juntao ZHANG Pingyu LO Kevin LI Jing LIU Shiwei | 2017 | Chinese Geographical Science2017，27，3： | 27 |
| 4 | Full-colour nanoprint-hologram synchronous metasurface with arbitrary hue-saturationbrightness control显示文摘The colour gamut,a two-dimensional(2D)colour space primarily comprising hue and saturation(HS),lays the most important foundation for the colour display and printing industries.Recently,the metasurface has been considered a promising paradigm for nanoprinting and holographic imaging,demonstrating a subwavelength image resolution,a flat profile,high durability,and multi-functionalities.Much effort has been devoted to broaden the 2D HS plane,also known as the CIE map.However,the brightness(B),as the carrier of chiaroscuro information,has long been neglected in metasurface-based nanoprinting or holograms due to the challenge in realising arbitrary and simultaneous control of full-colour HSB tuning in a passive device.Here,we report a dielectric metasurface made of crystal silicon nanoblocks,which achieves not only tailorable coverage of the primary colours red,green and blue(RGB)but also intensity control of the individual colours.The colour gamut is hence extruded from the 2D CIE to a complete 3D HSB space.Moreover,thanks to the independent control of the RGB intensity and phase,we further show that a singlelayer silicon metasurface could simultaneously exhibit arbitrary HSB colour nanoprinting and a full-colour hologram image.Our findings open up possibilities for high-resolution and high-fidelity optical security devices as well as advanced cryptographic approaches. | Yanjun Bao Ying Yu Haofei Xu Chao Guo Juntao Li Shang Sun Zhang-Kai Zhou Cheng-Wei Qiu Xue-Hua Wang | 2019 | Light(Science & Applications)2019，8，1： | 25 |
| 5 | Chemical characteristics of PM_(2.5) during dust storms and air pollution events in Chengdu,China显示文摘每天好的微粒(PM2.5 ) 样品从 2009 年 4 月在 Chengdu 被收集到 2010 年 2 月在灰尘暴风雨(决策支持系统) 和污染事件的几种类型期间调查他们的化学侧面,包括薄雾(HD ) ,燃烧的生物资源(BB ) ,和焰火显示(FD ) 。最高的 PM2.5 集体集中在决策支持系统(283.3 g/m3 ) 期间被发现,列在后面由 FD (212.7 g/m3 ) , HD (187.3 g/m3 ) ,和 BB (130.1 g/m3 ) 。大多数元素的集中在决策支持系统和污染事件期间被提高,除了 BB。第二等的无机的离子(NO3, SO42,和 NH4+) 在 HD 期间被充实,当从 BB 的 PM2.5 显示出高 K+ 时但是低 SO42。FD 在 SO42 在 K+ 和丰富引起了增加。Ca2+ 充满 DS 样品。离子平衡计算从 HD 显示了那 PM2.5, FD 比在正常的天更酸,但是 DS 和 BB 粒子是碱的。最高器官的碳(OC ) 集中在 FD 期间是 26.1 g/m3,列在后面由 BB (23.6 g/m3 ) , HD (19.6 g/m3 ) ,和决策支持系统(18.8 g/m3 ) 。相反,元素的碳(EC ) 集中比在 BB (6.2 g/m3 ) 和决策支持系统(6.0 g/m3 ) 期间在 HD (10.6 g/m3 ) 和 FD (9.5 g/m3 ) 期间是更丰富的。最高的 OC/EC 比率在 BB 期间被获得,与在 HD 期间最低。SO42/K+ 和 TCA/SO42 比率证明了是为区分污染事件的有效指示物。集体平衡证明那有机物, SO42,和 NO3 在污染事件期间是主导的化学部件,当土壤灰尘在决策支持系统期间是主导的时。 | Qiyuan Wang Junji Cao Zhenxing Shen JunTao Shun Xiao Lei Luo Qingyang He Xinying Tang | 2013 | Particuology2013，11，1： | 23 |
| 6 | Improvement of snow depth retrieval for FY3B-MWRI in China显示文摘The primary objective of this work is to develop an operational snow depth retrieval algorithm for the FengYun3B Microwave Radiation Imager(FY3B-MWRI)in China.Based on 7-year(2002–2009)observations of brightness temperature by the Advanced Microwave Scanning Radiometer-EOS(AMSR-E)and snow depth from Chinese meteorological stations,we develop a semi-empirical snow depth retrieval algorithm.When its land cover fraction is larger than 85%,we regard a pixel as pure at the satellite passive microwave remote-sensing scale.A 1-km resolution land use/land cover(LULC)map from the Data Center for Resources and Environmental Sciences,Chinese Academy of Sciences,is used to determine fractions of four main land cover types(grass,farmland,bare soil,and forest).Land cover sensitivity snow depth retrieval algorithms are initially developed using AMSR-E brightness temperature data.Each grid-cell snow depth was estimated as the sum of snow depths from each land cover algorithm weighted by percentages of land cover types within each grid cell.Through evaluation of this algorithm using station measurements from 2006,the root mean square error(RMSE)of snow depth retrieval is about 5.6 cm.In forest regions,snow depth is underestimated relative to ground observation,because stem volume and canopy closure are ignored in current algorithms.In addition,comparison between snow cover derived from AMSR-E and FY3B-MWRI with Moderate-resolution Imaging Spectroradiometer(MODIS)snow cover products(MYD10C1)in January 2010 showed that algorithm accuracy in snow cover monitoring can reach 84%.Finally,we compared snow water equivalence(SWE)derived using FY3B-MWRI with AMSR-E SWE products in the Northern Hemisphere.The results show that AMSR-E overestimated SWE in China,which agrees with other validations. | JIANG LingMei WANG Pei ZHANG LiXin YANG Hu YANG JunTao | 2014 | Science China Earth Sciences2014，57，6： | 22 |
| 7 | Soil pH determines fungal diversity along an elevation gradient in Southwestern China显示文摘Fungi play important roles in ecosystem processes, and the elevational pattern of fungal diversity is still unclear. Here, we examined the diversity of fungi along a 1,000 m elevation gradient on Mount Nadu, Southwestern China. We used MiSeq sequencing to obtain fungal sequences that were clustered into operational taxonomic units(OTUs) and to measure the fungal composition and diversity. Though the species richness and phylogenetic diversity of the fungal community did not exhibit significant trends with increasing altitude, they were significantly lower at mid-altitudinal sites than at the base. The Bray-Curtis distance clustering also showed that the fungal communities varied significantly with altitude. A distance-based linear model multivariate analysis(DistLM) identified that soil pH dominated the explanatory power of the species richness(23.72%),phylogenetic diversity(24.25%) and beta diversity(28.10%) of the fungal community. Moreover, the species richness and phylogenetic diversity of the fungal community increased linearly with increasing soil pH(P<0.05). Our study provides evidence that pH is an important predictor of soil fungal diversity along elevation gradients in Southwestern China. | Dan Liu Guohua Liu Li Chen Juntao Wang Limei Zhang | 2018 | Science China(Life Sciences)2018，61，6： | 21 |
| 8 | Detrital zircon U-Pb ages of Late Cenozoic sediments from the Yangtze delta:Implication for the evolution of the Yangtze River显示文摘Detrital zircon grains of Late Cenozoic sediments dated back to ca.3.6 Ma from core DY03 in the Yangtze delta were dated by LA-ICP-MS,in order to investigate the sedimentary provenance and to find some clue for the evolution of the Yangtze River.Most of the detrital zircon U-Pb ages are distributed at 100 300 Ma,350 550 Ma,600 1000 Ma,1400 2000 Ma and 2200 2800 Ma,which correspond well with the main tectonic and magmatic events in the Yangtze drainage.The detrital zircon age patterns show distinct difference between the 3 samples below 189.8 m and other 6 above 189.8 m.43% 55% zircons in the 3 samples below 189.8 m fall within Cretaceous,while ages from 150 to 2800 Ma are distributed with no obvious peaks,which indicate the sedimentary provenance may be limited to the lower Yangtze drainage.The 6 samples above 189.8 m show similar age patterns,and the ages are relatively evenly distributed,indicating the sedimentary provenance broadened distinctly.All 6 samples deposited later than ca.3.2 Ma show age information from the upper Yangtze drainage (including the Emeishan large igneous province),indicating that the Three Gorges may have already been cut through by then. | JIA JunTao ZHENG HongBo HUANG XiangTong WU FuYuan YANG ShouYe | 2010 | Chinese Science Bulletin2010，55，15： | 20 |
| 9 | Multi-robot path planning based on a deep reinforcement learning DQN algorithm显示文摘The unmanned warehouse dispatching system of the‘goods to people’model uses a structure mainly based on a handling robot,which saves considerable manpower and improves the efficiency of the warehouse picking operation.However,the optimal performance of the scheduling system algorithm has high requirements.This study uses a deep Q-network(DQN)algorithm in a deep reinforcement learning algorithm,which combines the Q-learning algorithm,an empirical playback mechanism,and the volume-based technology of productive neural networks to generate target Q-values to solve the problem of multi-robot path planning.The aim of the Q-learning algorithm in deep reinforcement learning is to address two shortcomings of the robot path-planning problem:slow convergence and excessive randomness.Preceding the start of the algorithmic process,prior knowledge and prior rules are used to improve the DQN algorithm.Simulation results show that the improved DQN algorithm converges faster than the classic deep reinforcement learning algorithm and can more quickly learn the solutions to path-planning problems.This improves the efficiency of multi-robot path planning. | Yang Yang Li Juntao Peng Lingling | 2020 | CAAI Transactions on Intelligence Technology2020，5，3： | 15 |
| 10 | Amino-functionalized core-shell magnetic mesoporous composite microspheres for Pb(Ⅱ) and Cd(Ⅱ) removal显示文摘Amino-functionalized Fe3O4 @mesoporous SiO2 core-shell composite microspheres NH2-MS in created in multiple synthesis steps have been investigated for Pb(Ⅱ) and Cd(Ⅱ) adsorption.The microspheres were characterized by transmission electron microscope(TEM),scanning electron microscope(SEM),N2 adsorption-desorption,zeta potential measurements and vibrating sample magnetometer.Batch adsorption tests indicated that NH2-MS exhibited higher adsorption affinity toward Pb(Ⅱ) and Cd(Ⅱ) than MS did.The Langmuir model could fit the adsorption isotherm very well with maximum adsorption capacity of 128.21 and 51.81mg/g for Pb(Ⅱ) and Cd(Ⅱ),respectively,implying that adsorption processes involved monolayer adsorption.Pb(Ⅱ) and Cd(Ⅱ) adsorption could be well described by the pseudo second-order kinetics model,and was found to be strongly dependent on pH and humic acid.The Pb(Ⅱ)and Cd(Ⅱ)-loaded microspheres were effectively desorbed using 0.01mol/L HCl or EDTA solution.NH2-MS have promise for use as adsorbents in the removal of Pb(Ⅱ) and Cd(Ⅱ) in wastewater treatment processes. | Yulin Tang Song Liang Juntao Wang Shuili Yu Yilong Wang | 2013 | Journal of Environmental Sciences2013，25，4： | 14 |
| 11 | Catalpol ameliorates depressive-like behaviors in CUMS mice via oxidative stress-mediated NLRP3 inflammasome and neuroinflammation显示文摘The purpose of the present study was to investigate whether catalpol exhibited neuro-protective effects in chronic unpredictable mild stress(CUMS)mice through oxidative stress-mediated nucleotide-binding oligomerization domain,leucine-rich repeat,and pyrin-domain-containing 3(NLRP3)inflammasome and neuroinflammation. | Wu Haoran Wang Yalim Hu Juntao | 2021 | 解剖学杂志2021，44，S01： | 12 |
| 12 | Photoreduction of CO_2 to methanol over Bi_2S_3/CdS photocatalyst under visible light irradiation显示文摘The Bi2S3,CdS and Bi2S3/CdS photocatalysts were prepared by direct reactions between their corresponding salt and thiourea in a hy- drothermal autoclave.The photocatalytic activities of these photocatalysts for reducing CO2 to CH3OH under visible light irradiation have been investigated.The results show that the photocatalytic activity and visible light response of Bi2S3 are higher than those of CdS.The Bi2S3 modification can enhance the photocatalytic activity and visible light response of CdS.The photocatalytic activity of Bi2S3/CdS hetero-junction photocatalyst was the highest and the highest yields of methanol was 613μmol/g when the weight proportion of Bi2S3 to CdS was 15%,which was about three times as large as that of CdS or two times of that of Bi2S3. | Xin Li Juntao Chen Huiling Li Jingtian Li Yitao Xu Yingju Liu Jiarong Zhou | 2011 | Journal of Natural Gas Chemistry2011，20，4： | 11 |
| 13 | Alkaline polymer electrolyte fuel cells: Principle, challenges, and recent progress显示文摘Polymer electrolyte membrane fuel cells (PEMFC) have been recognized as a significant power source in future energy systems based on hydrogen. The current PEMFC technology features the employment of acidic polymer electrolytes which, albeit superior to electrolyte solutions, have intrinsically limited the catalysts to noble metals, fundamentally preventing PEMFC from widespread deployment. An effective solution to this problem is to develop fuel cells based on alkaline polymer electrolytes (APEFC), which not only enable the use of non-precious metal catalysts but also avoid the carbonate-precipitate issue which has been troubling the conventional alkaline fuel cells (AFC). This feature article introduces the principle of APEFC, the challenges, and our research progress, and focuses on strategies for developing key materials, including high-performance alkaline polyelectrolytes and stable non-precious metal catalysts. For alkaline polymer electrolytes, high ionic conductivity and satisfactory mechanical property are difficult to be balanced, therefore polymer cross-linking is an ultimate strategy. For non-precious metal catalysts, it is urgent to improve the catalytic activity and stability. New materials, such as transition-metal complexes, nitrogen-doped carbon nanotubes, and metal carbides, would become applicable in APEFC. | TANG DaoPing, PAN Jing, LU ShanFu, ZHUANG Lin* & LU JunTao Hubei Key Lab of Electrochemical Power Sources College of Chemistry and Molecular Sciences, Wuhan University, Wuhan 430072, China | 2010 | Science China Chemistry2010，53，2： | 9 |
| 14 | Expert consensus on the glycemic management of critically ill patients显示文摘Introduction The incidence of hyperglycemia is 40-60%in critically ill patients and is up to 60-80%in those who have undergone car-diac surgery.[1]The results of an epidemiological study in the United States showed that 28.6%of diabetic patients and 9.3%of non-diabetic patients had elevated mean daily glucose on the day of ICU admission.[2]In critically ill patients,elevated blood glucose is primarily the result of stress,and stress-induced hy-perglycemia is an independent risk factor associated with prog-nosis,regardless of a previous diagnosis of diabetes.Nutritional therapy has become an integral treatment option for patients in the ICU,[3,4]though nearly 30%of patients with enteral nu-trition and 44-50%with parenteral nutrition(PN)experience elevated glucose.[5,6]Intensive insulin therapy(IIT)is an impor-tant treatment for controlling hyperglycemia in critically ill pa-tients,but it also carries a corresponding risk of hypoglycemia. | Zhixiong Wu Jiao Liu Dong Zhang Kai Kang Xiangrong Zuo Qianghong Xu Aijun Pan Wei Fang Fen Liu You Shang Haiyan Yin Juntao Hu Jinglun Liu Jiangquan Fu Wei Zhang Yuan Zong Min Shao Feng Zhao Mei Meng Yanfei Mao Yingchuan Li Dechang Chen | 2022 | Journal of Intensive Medicine2022，2，3： | 9 |
| 15 | Analysis of genetic architecture and favorable allele usage of agronomic traits in a large collection of Chinese rice accessions显示文摘Genotyping and phenotyping large natural populations provide opportunities for population genomic analysis and genome-wide association studies(GWAS). Several rice populations have been re-sequenced in the past decade;however, many major Chinese rice cultivars were not included in these studies. Here, we report large-scale genomic and phenotypic datasets for a collection mainly comprised of 1,275 rice accessions of widely planted cultivars and parental hybrid rice lines from China. The population was divided into three indica/Xian and three japonica/Geng phylogenetic subgroups that correlate strongly with their geographic or breeding origins. We acquired a total of 146 phenotypic datasets for 29 agronomic traits under multi-environments for different subpopulations. With GWAS, we identified a total of 143 significant association loci, including three newly identified candidate genes or alleles that control heading date or amylose content. Our genotypic analysis of agronomically important genes in the population revealed that many favorable alleles are underused in elite accessions, suggesting they may be used to provide improvements in future breeding efforts. Our study provides useful resources for rice genetics research and breeding. | Xiuxiu Li Zhuo Chen Guomin Zhang Hongwei Lu Peng Qin Ming Qi Ying Yu Bingke Jiao Xianfeng Zhao Qiang Gao Hao Wang Yunyu Wu Juntao Ma Liyan Zhang Yongli Wang Lingwei Deng Shanguo Yao Zhukuang Cheng Diqiu Yu Lihuang Zhu Yongbiao Xue Chengcai Chu Aihong Li Shigui Li Chengzhi Liang | 2020 | Science China(Life Sciences)2020，63，11： | 8 |
| 16 | Adaptive Backstepping Slide Mode Control of Pneumatic Position Servo System显示文摘With the price decreasing of the pneumatic proportional valve and the high performance micro controller, the simple structure and high tracking performance pneumatic servo system demonstrates more application potential in many fields. However, most existing control methods with high tracking performance need to know the model information and to use pressure sensor. This limits the application of the pneumatic servo system. An adaptive backstepping slide mode control method is proposed for pneumatic position servo system. The proposed method designs adaptive slide mode controller using backstepping design technique. The controller parameter adaptive law is derived from Lyapunov analysis to guarantee the stability of the system. A theorem is testified to show that the state of closed-loop system is uniformly bounded, and the closed-loop system is stable. The advantages of the proposed method include that system dynamic model parameters are not required for the controller design, uncertain parameters bounds are not need, and the bulk and expensive pressure sensor is not needed as well. Experimental results show that the designed controller can achieve better tracking performance, as compared with some existing methods. | REN Haipeng FAN Juntao | 2016 | Chinese Journal of Mechanical Engineering2016，29，5： | 8 |
| 17 | Late Paleozoic reefs and their significance for tectonics and oil-gas exploration in the Hinggan-Inner Mongolia area显示文摘Many reefs of the Late Paleozoic have been discovered recently in the Hinggan-Inner Mongolia area.These reefs clearly are geographically extensive,and possess distinctive features and well-developed reef-facies.They have been found to contain five reef-building communities and were constructed in four periods.Colonial coral-algal reefs at Aohan and Chifeng represent a warm shallow-sea in the Carboniferous.Different reefs in the Xiwu Banner were formed in three periods:early Late Carboniferous,late Late Carboniferous and Early Permian.These reefs were built in warm sea conditions.Their buildup types include colonial coral frameworks,algae-buildings and lime-mud mounds.Bryozoan reefs in the Zhalaite and Dongwu banners were built in the late Middle Permian and thrived in a cold shallow-sea.All reefs grew independently on two kinds of sedimentary platforms,carbonate and carbonate-clastic mixed platforms.Four reef-forming periods occurred later from south to north,along a collisional course between the North China Plate and the Siberian Plate.These reefs can be arranged into three 'reef-links' or reef zones that extend along plate margins.Among these,the Aohan-Chifeng reef-link indicates a northern margin of the North China Plate,the Zhalaite-Dongwu reef-link marks a southern margin of the Siberian Plate,and the Xiwu-Beishan reef-link reflects the former existence of some inter-plates.The strata of each reef-facies are thick and contain rich asphalt deposits.Overlapping and heteropic layers are very thick and contain dark oil/gas-rich horizons;TOC analyses verify that most of these are good hydrocarbon source rocks.This study shows that the study area is an excellent candidate for oil-gas exploration. | TIAN ShuGang ZHANG YongSheng WANG JunTao NIU ShaoWu | 2011 | Science China Earth Sciences2011，54，2： | 8 |
| 18 | Immunopotentiator Thymosin Alpha-1 Promotes Neurogenesis and Cognition in the Developing Mouse via a Systemic Th1 Bias显示文摘In early life, the immune system plays an essential role in brain development. In our study, the immunopotentiator thymosin alpha-1(Ta1) was peripherally administered to neonatal mice to explore whether the peripheral immunopotentiator affects neurodevelopment and cognition, and to further investigate the relevant mechanism. Compared with the control group, the Ta1 mice displayed better cognitive abilities in early life. The numbers of 5-bromodeoxyuridine(Brd U)+, nestin+,T-box transcription factor 2(Tbr2)+, Brd U+/doublecortin(DCX)+, Brd U+/ionized calcium-binding adaptor molecule 1(Iba1)+, and Brd U+/neuronal nuclei(Neu N)+ cells in the hippocampus were increased in the Ta1 group,accompanied by increased interleukin-4(IL-4), interferon-gamma, brain-derived neurotrophic factor, nerve growth factor, and insulin-like growth factor-1 as well as decreased IL-6 and tumor necrosis factor-a. Furthermore, the Ta1-group showed a Th1-polarized immune response, and the neurotrophic factors were positively associated with the Th1/Th2 ratio. More importantly, administration of Ta1 blocked lipopolysaccharide-induced impairment of hippocampal neurogenesis in early life. These findings suggest that peripheral Ta1 contributes to neurogenesis and cognition probably through a systemic Th1 bias, as well as neuroprotection against LPS infection by Ta1. | Ge Wang Fen He Yunlong Xu Yuwei Zhang Xiao Wang Chunhua Zhou Yihong Huang Juntao Zou | 2017 | Neuroscience Bulletin2017，33，6： | 8 |
| 19 | Research progresses on Cherenkov and transit-time high-power microwave sources at NUDT显示文摘Research progresses on Cherenkov and transit-time high-power microwave(HPM)sources in National University of Defense Technology(NUDT)of China are presented.The research issues are focused on the following aspects.The pulse-shortening phenomenon in O-type Cerenkov HPM devices is suppressed.The compact coaxial relativistic backward-wave oscillators(RBWOs)at low bands are developed.The power efficiency in M-Type HPM tubes without guiding magnetic field increased.The power capacities and power efficiencies in the triaxial klystron amplifier(TKA)and relativistic transit-time oscillator(TTO)at higher frequencies increased.In experiments,some exciting results were obtained.The X-band source generated 2 GW microwave power with a pulse duration of 110 ns in 30 Hz repetition mode.Both L-and P-band compact RBWOs generated over 2 GW microwave power with a power efficiency of over 30%.There is approximately a 75% decline of the volume compared with that of conventional RBWO under the same power capacity conditions.A 1.755 GHz MILO produced 3.1 GW microwave power with power efficiency of 10.4%.A 9.37 GHz TKA produced the 240 MW microwave power with the gain of 34 dB.A 14.3 GHz TTO produced 1 GW microwave power with power efficiency of 20%. | Jiande Zhang Xingjun Ge Jun Zhang Juntao He Yuwei Fan Zhiqiang Li Zhenxing Jin Liang Gao Junpu Ling Zumin Qi | 2016 | Matter and Radiation at Extremes2016，1，3： | 7 |
| 20 | Aerodynamic design optimization by using a continuous adjoint method显示文摘This paper presents the fundamentals of a continuous adjoint method and the applications of this method to the aerodynamic design optimization of both external and internal flows.General formulation of the continuous adjoint equations and the corresponding boundary conditions are derived.With the adjoint method,the complete gradient information needed in the design optimization can be obtained by solving the governing flow equations and the corresponding adjoint equations only once for each cost function,regardless of the number of design parameters.An inverse design of airfoil is firstly performed to study the accuracy of the adjoint gradient and the effectiveness of the adjoint method as an inverse design method.Then the method is used to perform a series of single and multiple point design optimization problems involving the drag reduction of airfoil,wing,and wing-body configuration,and the aerodynamic performance improvement of turbine and compressor blade rows.The results demonstrate that the continuous adjoint method can efficiently and significantly improve the aerodynamic performance of the design in a shape optimization problem. | LUO JiaQi XIONG JunTao LIU Feng | 2014 | Science China(Physics,Mechanics & Astronomy)2014，57，7： | 7 |
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