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| 1 | Internet of Things to network smart devices for ecosystem monitoring显示文摘Smart, real-time, low-cost, and distributed ecosystem monitoring is essential for understanding and managing rapidly changing ecosystems. However, new techniques in the big data era have rarely been introduced into operational ecosystem monitoring, particularly for fragile ecosystems in remote areas.We introduce the Internet of Things(IoT) techniques to establish a prototype ecosystem monitoring system by developing innovative smart devices and using IoT technologies for ecosystem monitoring in isolated environments. The developed smart devices include four categories: large-scale and nonintrusive instruments to measure evapotranspiration and soil moisture, in situ observing systems for CO2 and d13 C associated with soil respiration, portable and distributed devices for monitoring vegetation variables, and Bi-CMOS cameras and pressure trigger sensors for terrestrial vertebrate monitoring. These new devices outperform conventional devices and are connected to each other via wireless communication networks. The breakthroughs in the ecosystem monitoring IoT include new data loggers and longdistance wireless sensor network technology that supports the rapid transmission of data from devices to wireless networks. The applicability of this ecosystem monitoring IoT is verified in three fragile ecosystems, including a karst rocky desertification area, the National Park for Amur Tigers, and the oasis-desert ecotone in China. By integrating these devices and technologies with an ecosystem monitoring information system, a seamless data acquisition, transmission, processing, and application IoT is created. The establishment of this ecosystem monitoring IoT will serve as a new paradigm for ecosystem monitoring and therefore provide a platform for ecosystem management and decision making in the era of big data. | Xin Li Ning Zhao Rui Jin Shaomin Liu Xiaomin Sun Xuefa Wen Dongxiu Wu Yan Zhou Jianwen Guo Shiping Chen Ziwei Xu Mingguo Ma Tianming Wang Yonghua Qu Xinwei Wang Fangming Wu Yuke Zhou | 2019 | Science Bulletin2019，64，17： | 10 |
| 2 | The synthesis of 6-(tert-butyl)-8-fluoro-2,3-dimethylquinoline carbonate derivatives and their antifungal activity against Pyricularia oryzae显示文摘A series of novel 6-(/er/-butyl)-8-fluoro-2,3- dimethylquinoline carbonate derivatives were designed and synthesized. Bioassay results showed that some of them exhibited good activity against Pyricularia oryzae (P. oryzae). It was found that the compound 5q (benzyl (6-(tert-butyl)-8-fluoro-2,3-dimethylquinolin-4-yl) carbonate) possessed good activity against P. oryzae whatever protective activity (10 mg·L^-1) or curative activity (25 mg·L^-1), which was better than that of control tebufloquin. In addition, the frontier molecular orbit results revealed that the compound held higher activity against P. oryzae when the total energy was low and the ClogP was high, which may provide useful information for further design novel fungicides. | Long Cheng Ruirui Zhang Hongke Wu Xinghai Liu Tianming Xu | 2019 | Frontiers of Chemical Science and Engineering2019，13，2： | 8 |
| 3 | Synthesis and in vivo nematocidal evaluation of novel 3-(trifluoromethyl)-lH-pyrazole-4-carboxamide derivatives显示文摘 | Wen Zhao Jiahua Xing Tianming Xu Weili Peng Xinghai Liu | 2017 | Frontiers of Chemical Science and Engineering2017，11，3： | 5 |
| 4 | Genomic and transcriptomic analysis unveils population evolution and development of pesticide resistance in fall armyworm Spodoptera frugiperda显示文摘The fall armyworm(FAW),Spodoptera frugiperda,is a destructive pest native to America and has recently become an invasive insect pest in China.Because of its rapid spread and great risks in China,understanding of FAW genetic background and pesticide resistance is urgent and essential to develop effective management strategies.Here,we assembled a chromosome-level genome of a male FAW(SFynMstLFR)and compared re-sequencing results of the populations from America,Africa,and China.Strain identification of 163 individuals collected from America,Africa and China showed that both C and R strains were found in the American pop-ulations,while only C strain was found in the Chinese and African populations.Moreover,population geno-mics analysis showed that populations from Africa and China have close relationship with significantly genetic differentiation from American populations.Taken toge-ther,FAWs invaded into China were most likely origi-nated from Africa.Comparative genomics analysis displayed that the cytochrome p450 gene family is extremely expanded to 425 members in FAW,of which 283 genes are specific to FAW.Treatments of Chinese populations with twenty-three pesticides showed the variant patterns of transcriptome profiles,and several detoxification genes such as AOX,UGT and GST spe-cially responded to the pesticides.These findings will be useful in developing effective strategies for manage-ment of FAW in China and other invaded areas. | Furong Gui Tianming Lan Yue Zhao Wei Guo Yang Dong Dongming Fang Huan Liu Haimeng Li Hongli Wang Ruoshi Hao Xiaofang Cheng Yahong Li Pengcheng Yang Sunil Kumar Sahu Yaping Chen Le Cheng Shuqi He Ping Liu Guangyi Fan Haorong Lu Guohai Hu Wei Dong Bin Chen Yuan Jiang Yongwei Zhang Hanhong Xu Fei Lin Bernard Slippers Alisa Postma Matthew Jackson Birhan Addisie Abate Kassahun Tesfaye Aschalew Lemma Demie Meseret Destaw Bayeleygne Dawit Tesfaye Degefu Feng Chen Paul K.Kuria Zachary M.Kinyua Tong-Xian Liu Huanming Yang Fangneng Huang Xin Liu Jun Sheng Le Kang | 2022 | Protein & Cell2022，13，7： | 2 |
| 5 | Simultaneous determination of Repaglinide and Irbesartan in biological plasmas using micellar enhanced excitation-emission matrix fluorescence coupled with ATLD method显示文摘A highly sensitive and selective 3D excitation-emission fluorescence method has been proposed to rapidly quantify the combined antidiabetics Repaglinide(Re) and Irbesartan(Ir) in rat and human plasmas with the aid of second-order calibration method based on alternating trilinear decomposition(ATLD) method. Re and Ir with weak fluorescence can be endowed with strong fluorescent property by changing the microenvironment in samples and improving the fluorescence quantum yield by using an appropriate micellar enhanced surfactant. The enhanced excitation-emission matrix fluorescence of Re and Ir can be accurately resolved and can simultaneously attain the optimal concentration even in the presence of a potentially strong intrinsic fluorescence from complex biological matrices, such as rat and human plasmas, by using the ATLD method, which completely exploits the 'second-order advantage'. The average recoveries of Re and Ir obtained from ATLD with the factor number of 3(N=3) were 101.0%±4.3% and 99.1%±4.1% for rat plasma and 100.5%±5.4% and 97.1%±3.6% for human plasma. Several statistical methods, including Student's t-test, figures of merit, and elliptical joint confidence region, have been utilized to evaluate the accuracy of the proposed method. Results show that the developed method can maintain second-order advantage in simultaneous determinations of the weak fluorescent analytes of interest in different biological plasma matrices. | Haiyan Fu Hedong Li Mei Shao Tianming Yang Xu Zhang Rujing Xu Yujuan Wei Shuhua Chen Chuang Ni Hailong Wu | 2016 | Science China Chemistry2016，59，7： | 1 |
| 6 | Optimization of process parameters for preparation of powdered activated coke to achieve maximum SO_(2)adsorption using response surface methodology显示文摘Powdered activated coke(PAC)is a good adsorbent of SO_(2),but its adsorption capacity is affected by many factors in the preparation process.To prepare the PAC with a high SO_(2)adsorption capacity using JJ-coal under flue gas atmosphere,six parameters(oxygen-coal equivalent ratio,reaction temperature,reaction time,O_(2)concentration,CO_(2)concentration,and H_(2)O concentration)were screened and optimized using the response surface methodology(RSM).The results of factor screening experiment show that reaction temperature,O_(2)concentration,and H_(2)O(g)concentration are the significant factors.Then,a quadratic polynomial regression model between the significant factors and SO_(2)adsorption capacity was established using the central composite design(CCD).The model optimization results indicate that when reaction temperature is 904.74℃,O_(2)concentration is 4.67%,H_(2)O concentration is 27.98%,the PAC(PAC-OP)prepared had a higher SO_(2)adsorption capacity of 68.15 mg/g while its SO_(2)adsorption capacity from a validation experiment is 68.82 mg/g,and the error with the optimal value is 0.98%.Compared to two typical commercial activated cokes(ACs),PAC-OP has relatively more developed pore structures,and its SBET and Vtot are 349 m^(2)/g and 0.1475 cm3/g,significantly higher than the 186 m^(2)/g and 0.1041 cm3/g of AC1,and the 132 m^(2)/g and 0.0768 cm3/g of AC2.Besides,it also has abundant oxygen-containing functional groups,its surface O content being 12.09%,higher than the 10.42%of AC1 and 10.49%of AC2.Inevitably,the SO_(2)adsorption capacity of PAC-OP is also significantly higher than that of both AC1 and AC2,which is 68.82 mg/g versus 32.53 mg/g and 24.79 mg/g,respectively. | Binxuan ZHOU Tao WANG Tianming XU Cheng LI Yuan ZHAO Jiapeng FU Zhen ZHANG Zhanlong SONG Chunyuan MA | 2021 | Frontiers in Energy2021，15，1： | 0 |
| 7 | Amorphous hollow carbon film as a flexible host for liquid Na-K alloy anode显示文摘Compared with solid alkali metal anodes(Li, Na, K), liquid metal anodes(LMAs) could enable high-energy batteries due to their unique advantages, such as self-healing property and no dendrites. Among LMAs,liquid Na-K alloy anode has become a hotspot due to its high theoretical capacity, low redox potential and formation at room temperature(RT). However, it is challenging to utilize liquid Na-K alloy directly and independently as an electrode;and the high surface tension makes it more difficult to immerse into porous current collectors at RT. Herein, an amorphous hollow carbon film(AHCF) consisting of hollow spheres with significant surface defects has been designed to quickly infiltrate Na-K liquid alloy into the hollow carbon film at RT, forming a composite electrode(Na-K@AHCF). The symmetric cell with Na-K@AHCF could exhibit a cycle lifespan up to 400 h at 0.1 m A/cm^(2) and achieve stable stripping/deposition even at 5 mA/cm^(2). When matching with cathode material of sulfurized polyacrylonitrile(SPAN), the obtained K-S full cell exhibits good cycle stability and rate performance. | Meng Shao Ningxiang Wu Tianming Chen Xu Han Yu Shen Weina Zhang Bing Zheng Sheng Li Fengwei Huo | 2023 | Chinese Chemical Letters2023，34，7： | 0 |
| 8 | Upregulation of Zip14 correlates with induction of endoplasmic reticulum stress(ERS)in hypertrophied hearts of Dahl saltsensitive rats显示文摘Zinc is a trace element involved in maintaining cellular structure and function.Although zinc is associated with left ventricular hypertrophy(LVH),there have been few reports on this association.This study aimed to evaluate the correlation between Zip14 and expression of endoplasmic reticulum stress(ERS)associated molecules in hypertrophied hearts of rats.Dahl salt-sensitive rats were fed a high salt diet to establish a left ventricular hypertrophy(LVH)rat model.RT-PCR was used to determine Zip14,activating transcription factor(ATF4),ATF6,x-box-binding protein 1(xBP1),C/EBP homologous protein(CHOP),immunoglobulin-binding protein(BiP)mRNA expression.Western blotting was used to evaluate Zip14,BiP,CHOP,GAPDH expression.Zinc levels were measured by Inductively Coupled Plasma Optical Emission Spectroscopy.The results indicated that compared with the Control group,Zip14 mRNA and protein expression in LVH rat hearts were markedly increased(P<0.01).Zinc content in rat heart tissue was significantly increased in the LVH group compared with the Control group(P<0.05).ATF4,ATF6,xBP1 mRNA expressions were increased in LVH rat hearts compared with Control hearts(P<0.001).Compared with the Control group,CHOP and BiP mRNA and protein expression were markedly increased in LVH rat hearts(P<0.05,P<0.01).Linear regression models showed that Zip14 mRNA expressions were positively correlated with zinc concentration,ATF4 and ATF6 mRNA expressions in Control hearts(P=0.0005,P=0.0052,P=0.0026,respectively)and LVH rat hearts(P<0.0001,P=0.0119,P=0.0033,respectively).In conclusion,upregulation of Zip14 in LVH rat hearts correlated with zinc accumulation and induction of ERS. | JINYONG HUANG TIANMING TENG BO BIAN YUCHEN XUE LONGFEI HUANG ZHELONG XU QING YANG YUEMIN SUN | 2022 | BIOCELL2022，46，3： | 0 |
| 9 | Oxygen functional groups modified amorphous hollow carbon bowls for pseudocapacitive Zn-ion storage显示文摘Carbon is a promising capacitive electrode material for Zn-ion hybrid supercapacitors(ZHSCs),as it is low-cost,environmentally friendly,controllable and adjustable.By now,achieving both high energy and high power with carbon electrodes is still challenging,limited by their intrinsic properties.In this work,we have designed and presented an amorphous hollow carbon bowl material with surface chemical modifications of oxygen groups to figure out these concerns.The preparation of bowl-like structures and the storage behavior between Zn^(2+)and oxygen functional groups have also been discussed.With the contributions from its unique hollow structure and surface functional groups,it can significantly enhance the electrode pseudocapacitance and the entire electrochemical performance. | Gongxun Yu Fenghui Yang Xu Han Qiongyao Song Jiangtao Zheng Ying Qi Tianming Chen Qian Shen Jingxia Qiu Sheng Li | 2023 | Chinese Chemical Letters2023，34，12： | 0 |
| 10 | Targeting cAMP in D1-MSNs in the nucleus accumbens, a new rapid antidepressant strategy显示文摘Studies have suggested that the nucleus accumbens(NAc)is implicated in the pathophysiology of major depression;however,the regulatory strategy that targets the NAc to achieve an exclusive and outstanding anti-depression benefit has not been elucidated.Here,we identified a specific reduction of cyclic adenosine monophosphate(cAMP)in the subset of dopamine D1 receptor medium spiny neurons(D1-MSNs)in the NAc that promoted stress susceptibility,while the stimulation of cAMP production in NAc D1-MSNs efficiently rescued depression-like behaviors.Ketamine treatment enhanced cAMP both in D1-MSNs and dopamine D2 receptor medium spiny neurons(D2-MSNs)of depressed mice,however,the rapid antidepressant effect of ketamine solely depended on elevating cAMP in NAc D1-MSNs.We discovered that a higher dose of crocin markedly increased cAMP in the NAc and consistently relieved depression 24 h after oral administration,but not a lower dose.The fast onset property of crocin was verified through multicenter studies.Moreover,crocin specifically targeted at D1-MSN cAMP signaling in the NAc to relieve depression and had no effect on D2-MSN.These findings characterize a new strategy to achieve an exclusive and outstanding anti-depression benefit by elevating cAMP in D1-MSNs in the NAc,and provide a potential rapid antidepressant drug candidate,crocin. | Yue Zhang Jingwen Gao Na Li Peng Xu Shimeng Qu Jinqian Cheng Mingrui Wang Xueru Li Yaheng Song Fan Xiao Xinyu Yang Jihong Liu Hao Hong Ronghao Mu Xiaotian Li Youmei Wang Hui Xu Yuan Xie Tianming Gao Guangji Wang Jiye Aa | 2024 | Acta Pharmaceutica Sinica B2024，14，2： | 0 |
| 11 | Anti-Interference Low-Power Double-Edge Triggered Flip-Flop Based on C-Elements显示文摘When the input signal has been interfered and glitches occur,the power consumption of Double-Edge Triggered Flip-Flops(DETFFs)will significantly increase.To effectively reduce the power consumption,this paper presents an anti-interference low-power DETFF based on C-elements.The improved C-element is used in this DETFF,which effectively blocks the glitches in the input signal,prevents redundant transitions inside the DETFF,and reduces the charge and discharge frequencies of the transistor.The C-element has also added pull-up and pull-down paths,reducing its latency.Compared with other existing DETFFs,the DETFF proposed in this paper only flips once on the clock edge,which greatly reduces the redundant transitions caused by glitches and effectively reduces power consumption.This paper uses HSPICE to simulate the proposed DETFF and other 10 DETFFs.The findings show that compared with the other 10 types of DETFFs,the proposed DETFF has achieved large performance indexes in the total power consumption,total power consumption with glitches,delays,and power delay product.A detailed analysis of variance indicates that the proposed DETFF features less sensitivity to process,voltage,temperature,and Negative Bias Temperature Instability(NBTI)-induced aging variations. | Zhengfeng Huang Xiao Yang Tai Song Haochen Qi Yiming Ouyang Tianming Ni Qi Xu | 2022 | Tsinghua Science and Technology2022，27，1： | 0 |
| 12 | A novel ferroptosis-related microRNA signature with prognostic value in osteosarcoma显示文摘The induction of ferroptosis is suggested to be a potential therapeutic strategy for cancers.MicroRNAs(miRNAs)are reported to play an important role in cell death processes.This study aims to construct and validate a risk model based on ferroptosis-related miRNAs(FR_miRNAs)to predict prognosis and identify novel therapeutic targets for osteosarcoma.Data from the Therapeutically Applicable Research to Generate Effective Treatments database are used as the training cohort.A prognostic signature based on two FR_miRNAs(miR-635 and miR-593)is developed using univariate Cox regression,least absolute shrinkage and selection operator regression,and multivariate Cox regression analyses.The area under the curve values of the prognostic signature to predict the 1-year,2-year,3-year,and 5-year overall survival rates in patients with osteosarcoma are 0.782,0.781,0.722,and 0.777,respectively,indicating a good predictive ability.Based on the risk score,patients are divided into low-risk and high-risk groups.Patients with high-risk scores are associated with poor survival.The risk level is determined to be an independent prognostic factor.A nomogram is established for predicting prognosis.The expression levels of PRNP(miR-635-related ferroptosis-related gene(FRG);P=0.024)and HILPDA(miR-593-related FRG;P=0.025)are significantly different between the low-risk and high-risk groups.All results are validated in an external cohort(GSE39040).The results of the functional assay reveal that miR-635 mimics inhibit osteosarcoma(OS)cell proliferation and migra-tion,whereas miR-593 overexpression exerts the opposite effect.In conclusion,miR-635 and miR-593 exert con-trasting regulatory effects on OS cell proliferation and migration. | Jie Shao Yi Zhang Zhu Chang Shiyao Du Wei Li Yushu Bai Chunwen Lu Tianming Xu | 2023 | Acta Biochimica et Biophysica Sinica2023，55，11： | 0 |
| 13 | Study on direct point spread function measurement of capillary plate collimators with divergent X-ray beams显示文摘Purpose The Filed of View(FOV)of eXTP/LAD is limited by lead-glass capillary plate collimators placed in front of the Silicon Drift Detectors(SDDs)for reducing the background contamination caused by the photons of Cosmic X-ray Background(CXB)leaking from outside the FOV.The core quality parameters of lead-glass capillary plate collimators are Open Area Ratio(OAR)and FOV.The performance of lead-glass capillary plate collimators is determined by its design specification such as pore-to-pore misalignment,pore perpendicularity with collimator surface and pore diameter.Since the design specification is the result of a large number of micropores,we use the full width at half maximum(FWHM)and peak value of point spread function(PSF)to characterize the capillary plate collimator performance.In order to quickly evaluate the performances of collimators,we developed a direct PSF measurement method using divergent beams.Methods In this paper,the simulation package of the divergent beamsmeasurement setup is developed based on Geant4.The simulation parameters of scintillator absorption length are corrected by experimental data.We simulate the PSF of collimators with different distribution of pore diameter and misalignment by parallel beams and divergent beams.By comparing the peak value and FWHM of collimators PSF,the feasibility in replacing parallel beams measurement with divergent beams measurement is studied.Results It is verified that the influence of the geometric size of 33μm radius of the micro-focus of X-ray tube can be ignored.The results show that the FWHM of collimators is increased with error root mean square error(RMS)of the distribution of collimators pore diameter and pore inclination angle.The peak value of PSF is mainly influenced by pore non-parallelism of the pores,and it decreases with an increase in pore inclination angle.Comparison of parallel beams PSF and divergent beams PSF shows well consistency of peak value and FWHM of collimator.But,the peak value of the divergent beams PSF is mainly affected by the defects of the pores close to the optical axis and result in difference from the parallel beams results consequently.We have developed capillary plate collimators response function based on the projected area function of a cylindrical pore and the fluorescence broadening of the scintillator and fitted PSF by response function.The capillary plate collimator open area ratio is calculated by using the micropores radius and collimator frame thickness obtained by fitting parameter,and the result is close to the parallel beams PSF.Conclusion The feasibility divergent beams measurement is verified. | Tianming Li Tao Luo Yupeng Xu Huilin He Liming Song | 2023 | Radiation Detection Technology and Methods2023，7，3： | 0 |
| 14 | Tailored amorphous titanium oxide and carbon composites for enhanced pseudocapacitive sodium storage显示文摘As an effective and competitive supplement to the commercialized lithium ion batteries(LIBs),sodium ion batteries(SIBs)have been receiving increasing attention in recent years due to lower cost,richer content,and broader distribution of sodium[1–7].Sodium has similar electrochemical properties to lithium,and thus the concepts for the preparation of electrode materials for SIBs can be borrowed from LIBs[8,9]. | Meng Shao Chengcheng Sun Tianming Chen Ningxiang Wu Runan Zhang Xu Han Yu Shen Peng Wu Wei-Wei Xiong Weina Zhang Sheng Li Fengwei Huo | 2022 | Journal of Energy Chemistry2022，31，2： | 0 |
| 15 | Distinct and shared endothermic strategies in the heat producing tissues of tuna and other teleosts显示文摘Although most fishes are ectothermic,some,including tuna and billfish,achieve endothermy through specialized heat producing tissues that are modified muscles.How these heat producing tissues evolved,and whether they share convergent molecular mechanisms,remain unresolved.Here,we generated a high-quality genome from the mackerel tuna(Euthynnus affinis)and investigated the heat producing tissues of this fish by single-nucleus and bulk RNA sequencing.Compared with other teleosts,tuna-specific genetic variation is strongly associated with muscle differentiation.Single-nucleus RNA-seq revealed a high proportion of specific slow skeletal muscle cell subtypes in the heat producing tissues of tuna.Marker genes of this cell subtype are associated with the relative sliding of actin and myosin,suggesting that tuna endothermy is mainly based on shivering thermogenesis.In contrast,cross-species transcriptome analysis indicated that endothermy in billfish relies mainly on nonshivering thermogenesis.Nevertheless,the heat producing tissues of the different species do share some tissue-specific genes,including vascular-related and mitochondrial genes.Overall,although tunas and billfishes differ in their thermogenic strategies,they share similar expression patterns in some respects,highlighting the complexity of convergent evolution. | Baosheng Wu Xueli Gao Mingling Hu Jing Hu Tianming Lan Tingfeng Xue Wenjie Xu Chenglong Zhu Yuan Yuan Jiangmin Zheng Tao Qin Peidong Xin Ye Li Li Gong Chenguang Feng Shunping He Huan Liu Haimeng Li Qing Wang Zhenhua Ma Qiang Qiu Kun Wang | 2023 | Science China(Life Sciences)2023，66，11： | 0 |
| 16 | SAR Change Detection Algorithm Combined with FFDNet Spatial Denoising显示文摘Objectives:When detecting changes in synthetic aperture radar(SAR)images,the quality of the difference map has an important impact on the detection results,and the speckle noise in the image interferes with the extraction of change information.In order to improve the detection accuracy of SAR image change detection and improve the quality of the difference map,this paper proposes a method that combines the popular deep neural network with the clustering algorithm.Methods:Firstly,the SAR image with speckle noise was constructed,and the FFDNet architecture was used to retrain the SAR image,and the network parameters with better effect on speckle noise suppression were obtained.Then the log ratio operator is generated by using the reconstructed image output from the network.Finally,K-means and FCM clustering algorithms are used to analyze the difference images,and the binary map of change detection results is generated.Results:The experimental results have high detection accuracy on Bern and Sulzberger’s real data,which proves the effectiveness of the method. | Yuqing Wu Qing Xu Zheng Zhang Jingzhen Ma Tianming Zhao Xinming Zhu | 2023 | Journal of Environmental & Earth Sciences2023，5，2： | 0 |
| 17 | Clinicopathological features,endoscopic features,and treatment analysis of gastric neuroendocrine neoplasms显示文摘To the Editor:Gastric neuroendocrine neoplasms(gNENs)are highly heterogeneous tumors derived from different neuroendocrine cells in the stomach.Recent epidemiological evidence has indicated that gNENs account for 0.3%to 1.8%of all gastric malignancies.[1]However,few research data are available on gNENs in Chinese patients,but Chinese doctors need to improve their knowledge about this disease. | Ju Huang Xi Wu Tianming Xu Jingnan Li | 2022 | Chinese Medical Journal2022，135，20： | 0 |
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