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| 1 | Towards 6G wireless communication networks:vision,enabling technologies,and new paradigm shifts显示文摘The fifth generation(5G)wireless communication networks are being deployed worldwide from 2020 and more capabilities are in the process of being standardized,such as mass connectivity,ultra-reliability,and guaranteed low latency.However,5G will not meet all requirements of the future in 2030 and beyond,and sixth generation(6G)wireless communication networks are expected to provide global coverage,enhanced spectral/energy/cost efficiency,better intelligence level and security,etc.To meet these requirements,6G networks will rely on new enabling technologies,i.e.,air interface and transmission technologies and novel network architecture,such as waveform design,multiple access,channel coding schemes,multi-antenna technologies,network slicing,cell-free architecture,and cloud/fog/edge computing.Our vision on 6G is that it will have four new paradigm shifts.First,to satisfy the requirement of global coverage,6G will not be limited to terrestrial communication networks,which will need to be complemented with non-terrestrial networks such as satellite and unmanned aerial vehicle(UAV)communication networks,thus achieving a space-airground-sea integrated communication network.Second,all spectra will be fully explored to further increase data rates and connection density,including the sub-6GHz,millimeter wave(mmWave),terahertz(THz),and optical frequency bands.Third,facing the big datasets generated by the use of extremely heterogeneous networks,diverse communication scenarios,large numbers of antennas,wide bandwidths,and new service requirements,6G networks will enable a new range of smart applications with the aid of artificial intelligence(AI)and big data technologies.Fourth,network security will have to be strengthened when developing 6G networks.This article provides a comprehensive survey of recent advances and future trends in these four aspects.Clearly,6G with additional technical requirements beyond those of 5G will enable faster and further communications to the extent that the boundary between physical and cyber worlds disappears. | Xiaohu YOU Cheng-Xiang WANG Jie HUANG Xiqi GAO Zaichen ZHANG Mao WANG Yongming HUANG Chuan ZHANG Yanxiang JIANG Jiaheng WANG Min ZHU Bin SHENG Dongming WANG Zhiwen PAN Pengcheng ZHU Yang YANG Zening LIU Ping ZHANG Xiaofeng TAO Shaoqian LI Zhi CHEN Xinying MA Chih-Lin I Shuangfeng HAN Ke LI Chengkang PAN Zhimin ZHENG Lajos HANZO Xuemin(Sherman)SHEN Yingjie Jay GUO Zhiguo DING Harald HAAS Wen TONG Peiying ZHU Ganghua YANG Jun WANG Erik GLARSSON Hien Quoc NGO Wei HONG Haiming WANG Debin HOU Jixin CHEN Zhe CHEN Zhangcheng HAO Geoffrey Ye LI Rahim TAFAZOLLI Yue GAO HVincent POOR Gerhard P.FETTWEIS Ying-Chang LIANG | 2021 | Science China(Information Sciences)2021，64，1： | 122 |
| 2 | Rapid improvement of grain weight via highly efficient CRISPR/Cas9-mediated multiplex genome editing in rice显示文摘Most of the important agronomic traits in crop plants,such as yield,quality and stress response,are quantitative and jointly controlled by many genomic loci or major genes.Improving these complex traits depends on the combination of beneficial alleles at the quantitative trait loci(QTLs).However,the conventional cross breeding method is extremely time-consuming and laborious for pyramiding multiple QTLs.In certain cases,this approach | Rongfang Xu Yachun Yang Ruiying Qin Hao Li Chunhong Qiu Li Li Pengcheng Wei Jianbo Yang | 2016 | Journal of Genetics and Genomics2016，43，8： | 47 |
| 3 | Toward Intelligent Machine Tool显示文摘With the development of modern information technology-and particularly of the new generation of artificial intelligence(AI)technology-new opportunities are available for the development of the intelligent machine tool(IMT).Based on the three classical paradigms of intelligent manufacturing as defined by the Chinese Academy of Engineering,the concept,characteristics,and systemic structure of the IMT are presented in this paper.Three stages of machine tool evolution-from the manually operated machine tool(MOMT)to the IMT-are discussed,including the numerical control machine tool(NCMT),the smart machine tool(SMT),and the IMT.Furthermore,the four intelligent control principles of the IMT-namely,autonomous sensing and connection,autonomous learning and modeling,autonomous optimization and decision-making,and autonomous control and execution-are presented in detail.This paper then points out that the essential characteristic of the IMT is to acquire and accumulate knowledge through learning,and presents original key enabling technologies,including the instruction-domain-based analytical approach,theoretical and big-data-based hybrid modeling technology,and the double-code control method.Based on this research,an intelligent numerical control(INC)system and industrial prototypes of IMTs are developed.Three intelligent practices are conducted,demonstrating that the integration of the new generation of AI technology with advanced manufacturing technology is a feasible and convenient way to advance machine tools toward the IMT. | Jihong Chen Pengcheng Hu Huicheng Zhou Jianzhong Yang Jiejun Xie Yakun Jiang Zhiqiang Gao Chenglei Zhang | 2019 | Engineering2019，5，4： | 12 |
| 4 | Plate tectonic control on the formation and tectonic migration of Cenozoic basins in northern margin of the South China Sea显示文摘The tectonic evolution history of the South China Sea(SCS) is important for understanding the interaction between the Pacific Tectonic Domain and the Tethyan Tectonic Domain,as well as the regional tectonics and geodynamics during the multi-plate convergence in the Cenozoic.Several Cenozoic basins formed in the northern margin of the SCS,which preserve the sedimentary tectonic records of the opening of the SCS.Due to the spatial non-uniformity among different basins,a systematic study on the various basins in the northern margin of the SCS constituting the Northern Cenozoic Basin Group(NCBG) is essential.Here we present results from a detailed evaluation of the spatial-temporal migration of the boundary faults and primary unconformities to unravel the mechanism of formation of the NCBG.The NCBG is composed of the Beibu Gulf Basin(BBGB),Qiongdongnan Basin(QDNB),Pearl River Mouth Basin(PRMB) and Taixinan Basin(TXNB).Based on seismic profiles and gravity-magnetic anomalies,we confirm that the NE-striking onshore boundary faults propagated into the northern margin of the SCS.Combining the fault slip rate,fault combination and a comparison of the unconformities in different basins,we identify NE-striking rift composed of two-stage rifting events in the NCBG:an early-stage rifting(from the Paleocene to the Early Oligocene) and a late-stage rifting(from the Late Eocene to the beginning of the Miocene).Spatially only the late-stage faults occurs in the western part of the NCBG(the BBGB,the QDNB and the western PRMB),but the early-stage rifting is distributed in the whole NCBG.Temporally,the early-stage rifting can be subdivided into three phases which show an eastward migration,resulting in the same trend of the primary unconformities and peak faulting within the NCBG.The late-stage rifting is subdivided into two phases,which took place simultaneously in different basins.The first and second phase of the early-stage rifting is related to back-arc extension of the Pacific subduction retreat system.The third phase of the earlystage rifting resulted from the joint effect of slab-pull force due to southward subduction of the proto-SCS and the back-arc extension of the Pacific subduction retreat system.In addition,the first phase of the late-stage faulting corresponds with the combined effect of the post-collision extension along the Red River Fault and slab-pull force of the proto-SCS subduction.The second phase of the late-stage faulting fits well with the sinistral faulting of the Red River Fault in response to the Indochina Block escape tectonics and the slab-pull force of the proto-SCS. | Pengcheng Wang Sanzhong Li Yanhui Suo Lingli Guo Guangzeng Wang Gege Hui M.Santosh Ian D.Somerville Xianzhi Cao Yang Li | 2020 | Geoscience Frontiers2020，11，4： | 10 |
| 5 | Platelet-rich plasma accelerates skin wound healing by promoting re-epithelialization显示文摘Background:Autologous platelet-rich plasma(PRP)has been suggested to be effective for wound healing.However,evidence for its use in patients with acute and chronic wounds remains insufficient.The aims of this study were to comprehensively examine the effectiveness,synergy and possible mechanism of PRP-mediated improvement of acute skin wound repair.Methods:Full-thickness wounds were made on the back of C57/BL6 mice.PRP or saline solution as a control was administered to the wound area.Wound healing rate,local inflammation,angiogenesis,re-epithelialization and collagen deposition were measured at days 3,5,7 and 14 after skin injury.The biological character of epidermal stem cells(ESCs),which reflect the potential for re-epithelialization,was further evaluated in vitro and in vivo.Results:PRP strongly improved skin wound healing,which was associated with regulation of local inflammation,enhancement of angiogenesis and re-epithelialization.PRP treatment significantly reduced the production of inflammatory cytokines interleukin-17A and interleukin-1β.An increase in the local vessel intensity and enhancement of re-epithelialization were also observed in animals with PRP administration and were associated with enhanced secretion of growth factors such as vascular endothelial growth factor and insulin-like growth factor-1.Moreover,PRP treatment ameliorated the survival and activated the migration and proliferation of primary cultured ESCs,and these effects were accompanied by the differentiation of ESCs into adult cells following the changes of CD49f and keratin 10 and keratin 14.Conclusion:PRP improved skin wound healing by modulating inflammation and increasing angiogenesis and re-epithelialization.However,the underlying regulatory mechanism needs to be investigated in the future.Our data provide a preliminary theoretical foundation for the clinical administration of PRP in wound healing and skin regeneration. | Pengcheng Xu Yaguang Wu Lina Zhou Zengjun Yang Xiaorong Zhang Xiaohong Hu Jiacai Yang Mingying Wang Binjie Wang Gaoxing Luo Weifeng He Biao Cheng | 2020 | Burns & Trauma2020，8，1： | 8 |
| 6 | Procalcitonin could be a reliable marker in differential diagnosis of post-implantation syndrome and infection after percutaneous endovascular aortic repair显示文摘 | Xue Ling Luo Songyuan Luo Jianfang Liu Zhen Gu Mengnan Kang Huiyuan Yang Fan Nie Bingrong Liu Yuan Huang Wenhui Xie Nianjin He Pengcheng Dong Haojian Ni Zhonghan Fan Ruixin Chen Jiyan | 2014 | Chinese Medical Journal2014，，14： | 8 |
| 7 | Genome-wide variants of Eurasian facial shape differentiation and a prospective model of DNA based face prediction显示文摘It is a long-standing question as to which genes define the characteristic facial features among different ethnic groups. In this study, we use Uyghurs, an ancient admixed population to query the genetic bases why Europeans and Han Chinese look different. Facial traits were analyzed based on high-dense 3D facial images; numerous biometric spaces were examined for divergent facial features between European and Han Chinese, ranging from inter-landmark distances to dense shape geometrics. Genome-wide association studies(GWAS) were conducted on a discovery panel of Uyghurs. Six significant loci were identified, four of which, rs1868752, rs118078182, rs60159418 at or near UBASH3B, COL23A1, PCDH7 and rs17868256 were replicated in independent cohorts of Uyghurs or Southern Han Chinese. A prospective model was also developed to predict 3D faces based on top GWAS signals and tested in hypothetic forensic scenarios. | Lu Qiao Yajun Yang Pengcheng Fu Sile Hu Hang Zhou Shouneng Peng Jingze Tan Yan Lu Haiyi Lou Dongsheng Lu Sijie Wu Jing Guo Li Jin Yaqun Guan Sijia Wang Shuhua Xu Kun Tang | 2018 | Journal of Genetics and Genomics2018，45，8： | 7 |
| 8 | CRISPR/Cas9-Mediated Adenine Base Editing in Rice Genome显示文摘Precise base editing is highly desired in plant functional genomic research and crop molecular breeding. In this study, we constructed a rice-codon optimized adenine base editor(ABE)-nC as9 tool that induced targeted A·T to G·C point mutation of a key single nucleotide polymorphism site in an important agricultural gene. Combined with the modified single-guide RNA variant, our plant ABE tool can efficiently achieve adenine base editing in the rice genome. | LI Hao QIN Ruiying LIU Xiaoshuang LIAO Shengxiang XU Rongfang YANG Jianbo WEI Pengcheng | 2019 | Rice science2019，26，2： | 7 |
| 9 | Genetic mapping of quantitative trait loci in crops显示文摘Dissecting the genetic architecture of complex traits is an ongoing challenge for geneticists.Two complementary approaches for genetic mapping,linkage mapping and association mapping have led to successful dissection of complex traits in many crop species.Both of these methods detect quantitative trait loci(QTL) by identifying marker–trait associations,and the only fundamental difference between them is that between mapping populations,which directly determine mapping resolution and power.Based on this difference,we first summarize in this review the advances and limitations of family-based mapping and natural population-based mapping instead of linkage mapping and association mapping.We then describe statistical methods used for improving detection power and computational speed and outline emerging areas such as large-scale meta-analysis for genetic mapping in crops.In the era of next-generation sequencing,there has arisen an urgent need for proper population design,advanced statistical strategies,and precision phenotyping to fully exploit high-throughput genotyping. | Yang Xu Pengcheng Li Zefeng Yang Chenwu Xu | 2017 | The Crop Journal2017，5，2： | 7 |
| 10 | Genomic selection: A breakthrough technology in rice breeding显示文摘Rice(Oryza sativa)provides a staple food source for more than half the world population.However,the current pace of rice breeding in yield growth is insufficient to meet the food demand of the everincreasing global population.Genomic selection(GS)holds a great potential to accelerate breeding progress and is cost-effective via early selection before phenotypes are measured.Previous simulation and experimental studies have demonstrated the usefulness of GS in rice breeding.However,several affecting factors and limitations require careful consideration when performing GS.In this review,we summarize the major genetics and statistical factors affecting predictive performance as well as current progress in the application of GS to rice breeding.We also highlight effective strategies to increase the predictive ability of various models,including GS models incorporating functional markers,genotype by environment interactions,multiple traits,selection index,and multiple omic data.Finally,we envision that integrating GS with other advanced breeding technologies such as unmanned aerial vehicles and open-source breeding platforms will further improve the efficiency and reduce the cost of breeding. | Yang Xu Kexin Ma Yue Zhao Xin Wang Kai Zhou Guangning Yu Cheng Li Pengcheng Li Zefeng Yang Chenwu Xu Shizhong Xu | 2021 | The Crop Journal2021，9，3： | 7 |
| 11 | The Relationship Between the Gut Microbiome and Neurodegen-erative Diseases显示文摘Many recent studies have shown that the gut microbiome plays important roles in human physiology and pathology.Also,microbiome-based therapies have been used to improve health status and treat diseases.In addition,aging and neurodegenerative diseases,including Alzheimer’s disease and Parkinson’s disease,have become topics of intense interest in biomedical research.Several researchers have explored the links between these topics to study the potential pathogenic or therapeutic effects of intestinal microbiota in disease.But the exact relationship between neurodegenerative diseases and gut microbiota remains unclear.As technology advances,new techniques for studying the microbiome will be developed and refined,and the relationship between diseases and gut microbiota will be revealed.This article summarizes the known interactions between the gut microbiome and neurodegenerative diseases,highlighting assay techniques for the gut microbiome,and we also discuss the potential therapeutic role of microbiome-based therapies in diseases. | Xueling Zhu Bo Li Pengcheng Lou Tingting Dai Yang Chen Aoxiang Zhuge Yin Yuan Lanjuan Li | 2021 | Neuroscience Bulletin2021，37，10： | 6 |
| 12 | Synthesis of hexaaluminate catalysts for methane combustion by reverse microemulsion medium显示文摘The aim of this study is to synthesize the catalysts of Fe-and Mn-substituted hexaaluminate by reverse microemulsion medium for methane catalytic combustion application.Pseudo-ternary phase diagrams in quaternary microemulsion systems of cetyltrimethylammonium bromide(CTAB),n-butanol,n-octane,and water [or Al(NO3)3 solution] were presented.The effects of the alcohol chain length,ratio of sur-factant to cosurfactant,and salt concentration on the formation and stability of microemulsion systems were studied.The phase behavior of microemulsion systems was confirmed through the varying of the conductivity with the water content.The performance and structure of the catalysts,La(Mnx/Fex)Al12-x-O19-δ synthesized with the optimal parameter in the phase diagrams of microemulsions systems were characterized by BET,TG-DTA,and XRD.The micro fix-bed reactor was used to measure the catalytic activities of catalysts to methane combustion.The results showed that this synthesis method could yield non-agglomerated and highly dispersed precursors that would undergo crystallization at the lower temperature of 950℃.When temperature was raised up to 1050℃,the complete crystalline La-hexaaluminate was shaped.The hexaaluminate substituted with Fe had high-catalytic activity and stability at high temperature,while the Mn-substituted had higher catalytic activity at lower temperature.When the cooperation of Fe and Mn occurred,i.e.,LaFeMnAl10O19-δ exhibited a high surface area and catalytic activity to CH4 combustion,the CH4 light-off temperature was only 475℃ and the complete combustion temperature was 660℃.This was attributed to the synergistic effect between Fe and Mn. | BAI ShouLi WANG LiangShi SHI BingJie YANG PengCheng CUI MeiSheng LONG ZhiQi LI DianQing CHEN AiFan | 2009 | Science China Chemistry2009，52，1： | 6 |
| 13 | Cluster-formula-embedded machine learning for design of multicomponent β-Ti alloys with low Young’s modulus显示文摘The present work formulated a materials design approach,a cluster-formula-embedded machine learning(ML)model,to search for body-centered-cubic(BCC)β-Ti alloys with low Young’s modulus(E)in the Ti–Mo–Nb–Zr–Sn–Ta system.The characteristic parameters,including the Mo equivalence and the cluster-formula approach,are implemented into the ML to ensure the accuracy of prediction,in which the former parameter represents the BCC-βstructural stability,and the latter reflects the interactions among elements expressed with a composition formula.Both auxiliary gradient-boosting regression tree and genetic algorithm methods were adopted to deal with the optimization problem in the ML model. | Fei Yang Zhen Li Qing Wang Beibei Jiang Biaojie Yan Pengcheng Zhang Wei Xu Chuang Dong Peter K.Liaw | 2020 | npj Computational Materials2020，，1： | 5 |
| 14 | Two-step transmission with artificial noise for secure wireless SIMO communications显示文摘The issue of physical layer security of the wireless single-input multiple-output(SIMO) system is addressed in this paper. We propose a two-step transmission scheme with artificial noise to improve the security and the scheme does not require the channel state information of the eavesdropper. In the first step, the destination which has multiple antennas generates a random reference symbol and artificial noise and transmits them in the direction of the source and its orthogonal space, respectively. The reference symbol is received by the source without being polluted by the artificial noise, while it is jammed by the artificial noise for the eavesdropper. In the second step, the symbol of the source is multiplied by the received reference symbol and then transmitted. Finally, the destination can directly estimate the symbol of the source using the reference symbol. However, the eavesdropper needs to additionally estimate the reference symbol for demodulating the symbol of the source, which usually obtains an inaccurate result due to the artificial noise. The informationtheoretic security of our scheme is analyzed and a lower bound of the achievable secrecy rate is derived. The performance of the new scheme is compared with that of the traditional approach under different input signals through numerical simulations. The results show that the proposed scheme outperforms the traditional SIMO approach especially in the high SNR region. | WANG Bo MU PengCheng YANG PeiZhi YIN QinYe | 2015 | Science China(Information Sciences)2015，58，4： | 4 |
| 15 | Core transcriptional signatures of phase change in the migratory locust显示文摘Phenotypic plasticity plays fundamental roles in successful adaptation of animals in response to environmental variations.Here,to reveal the transcriptome reprogramming in locust phase change,a typical phenotypic plasticity,we conducted a comprehensive analysis of multiple phase-related transcriptomic datasets of the migratory locust.We defined PhaseCore genes according to their contribution to phase differentiation by the adjustment for confounding principal components analysis algorithm(AC-PCA).Compared with other genes,PhaseCore genes predicted phase status with over 87.5%accuracy and displayed more unique gene attributes including the faster evolution rate,higher CpG content and higher specific expression level.Then,we identified 20 transcription factors(TFs)named PhaseCoreTF genes that are associated with the regulation of PhaseCore genes.Finally,we experimentally verified the regulatory roles of three representative TFs(Hr4,Hr46,and grh)in phase change by RNAi.Our findings revealed that core transcriptional signatures are involved in the global regulation of locust phase changes,suggesting a potential common mechanism underlying phenotypic plasticity in insects.The expression and network data are accessible in an online resource called LocustMine(http://gffzz3cb74c7b86e54fech0b66bp0cqcfw69qb.ffgz.tsg.suse.edu.cn/locustmine). | Pengcheng Yang Li Hou Xianhui Wang Le Kang | 2019 | Protein & Cell2019，10，12： | 4 |
| 16 | Multi-beam and seismic investigations of the active Haima cold seeps,northwestern South China Sea显示文摘To confirm the seabed fluid flow at the Haima cold seeps,an integrated study of multi-beam and seismic data reveals the morphology and fate of four bubble plumes and investigates the detailed subsurface structure of the active seepage area.The shapes of bubble plumes are not constant and influenced by the northeastward bottom currents,but the water depth where these bubble plumes disappear(630–650 m below the sea level)(mbsl)is very close to the upper limit of the gas hydrate stability zone in the water column(620 m below the sea level),as calculated from the CTD data within the study area,supporting the“hydrate skin”hypothesis.Gas chimneys directly below the bottom simulating reflectors,found at most sites,are speculated as essential pathways for both thermogenic gas and biogenic gas migrating from deep formations to the gas hydrate stability zone.The fracture network on the top of the basement uplift may be heavily gas-charged,which accounts for the chimney with several kilometers in diameter(beneath Plumes B and C).The much smaller gas chimney(beneath Plume D)may stem from gas saturated localized strong permeability zone.High-resolution seismic profiles reveal pipe-like structures,characterized by stacked localized amplitude anomalies,just beneath all the plumes,which act as the fluid conduits conveying gas from the gas hydrate-bearing sediments to the seafloor,feeding the gas plumes.The differences between these pipe-like structures indicate the dynamic process of gas seepage,which may be controlled by the build-up and dissipation of pore pressure.The 3D seismic data show high saturated gas hydrates with high RMS amplitude tend to cluster on the periphery of the gas chimney.Understanding the fluid migration and hydrate accumulation pattern of the Haima cold seeps can aid in the further exploration and study on the dynamic gas hydrate system in the South China Sea. | Bin Liu Jiangxin Chen Li Yang Minliang Duan Shengxuan Liu Yongxian Guan Pengcheng Shu | 2021 | Acta Oceanologica Sinica2021，40，7： | 3 |
| 17 | Myotoxic activity of a Gln-49 phospholipase A_2 from Agkistrodon blomhoffii ussurensis snake venom显示文摘新奇 myotoxic 蛋白质 phospholipase A 2( 作为作为 Gln49-PLA 2, 表示的 Gln49-PLA 2, 表示的 PLA 2), 从 Agkistrodon blomhoffii ussurensis 的蛇恶意被孤立,它有弱致命的效果和明显的抗凝剂活动,但是缺乏 PLA 2 和 hemorrhagenic 活动。Gln49-PLA 2 显然在老鼠在肌内的注射之上血浆 creatine-kinase (CK ) 增加,建议它可以导致剂量依赖者 myonecrosis。组织学的研究也在老鼠揭示词法变化在对待的动物的骨胳的肌肉,包括的广泛的 myonecrosis,出血和嗜中性的渗入。Gln49-PLA 2 导致的 myotoxic 能力能被肝磷脂部分禁止。 | BAO Yongming BU Pengcheng YANG Jun YANG Wei JIA Peilin AN Lijia | 2006 | Progress in Natural Science:Materials International2006，16，2： | 3 |
| 18 | Can the Grain-for-Green Program Really Ensure a Low Sediment Load on the Chinese Loess Plateau?显示文摘The Chinese Loess Plateau is the most seriously eroded area in the world and contributes the vast majority of the sediment that goes into the Yellow River.Since the 1950s,progressive soil and water conservation measures have been implemented—in particular,large-scale ecological restoration has been ongoing since 1999—resulting in a significant reduction of the sediment load.However,the mechanism of the sediment transport dynamics is not fully understood due to multiple and complicated influencing factors including climate change and human activities(e.g.,ecological restoration).A challenging question,then,arises:Is the current low sediment level a“new normal”in this era and in the future?To address this question,we selected a typical loess hilly region where considerable ecological restoration has been implemented,and which is regarded as the site of the first and most representative Grainfor-Green program in the Loess Plateau.We investigated the evolution of discharge–sediment relationships in the past decades(1960–2010)and their association with the soil and water conservation measures in this area.The results showed that there was a distinct change in the regression parameters of the commonly used annual discharge–sediment regression equation—a continuously increasing trend of parameter b and a decreasing trend of parameter a,accompanying the ecological restoration.The increase in exponent b(i.e.,a steeper slope)implies a potential lower sediment load resulting from low discharge and a potential higher sediment load resulting from large discharge.This finding may question the new normal of a low sediment level and implies the potential risk of a large sediment load during extremely wet years. | Pengcheng Sun Yiping Wu Zhifeng Yang Bellie Sivakumar Linjing Qiu Shuguang Liu Yanpeng Cai | 2019 | Engineering2019，5，5： | 3 |
| 19 | Full-spectrum cell-free RAN for 6G systems:system design and experimental results显示文摘With distributed transceivers and scalable cooperative transmission,cell-free massive multipleinput multiple-output(CF-mMIMO)technology eliminates the“cells”of traditional mobile communications,thereby significantly improving the performance of wireless networks.CF-mMIMO is considered as a major technical tool for achieving the key performance indicators of sixth generation(6G)mobile communication systems.In this paper,a scalable implementation architecture for CF-mMIMO is proposed,based on which potential key technologies such as channel information acquisition,transceiver design,dynamic user and access point association,and novel duplexing are introduced.Finally,based on low-cost commercial access points,a CF-mMIMO testbed with 64 transmit and receive antennas is developed,and the performance of the distributed receiver design is evaluated. | Dongming WANG Xiaohu YOU Yongming HUANG Wei XU Jiamin LI Pengcheng ZHU Yanxiang JIANG Yang CAO Xinjiang XIA Ziyang ZHANG Qingji JIANG Pan WANG Dongjie LIU Kang ZHENG Mengting LOU Jing JIN Qixing WANG Jiangzhou WANG | 2023 | Science China(Information Sciences)2023，66，3： | 3 |
| 20 | Increasing fidelity and efficiency by modifying cytidine base-editing systems in rice显示文摘The efficiency of plant cytidine base-editing systems is limited, and unwanted mutations frequently occur in transgenic plants. We increased the cytidine editing frequency and fidelity of the plant base editor 3(BE3) and targeted activation-induced cytidine deaminase(CDA)(target-AID) systems by coexpressing three copies of free uracil–DNA glycosylase(UDG) inhibitor(UGI). The editing efficiency of the improved BE3 and CDA systems reached as high as 88.9% and 85.7%, respectively, in regenerated rice plants, with a very low frequency of unwanted mutations. The low editing frequency of the BE3 system in the GC context could be overcome by the modified CDA system. These results provide a highfidelity and high-efficiency solution for rice genomic base editing. | Ruiying Qin Shengxiang Liao Juan Li Hao Li Xiaoshuang Liu Jianbo Yang Pengcheng Wei | 2020 | The Crop Journal2020，8，3： | 3 |
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