|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | A complete sequence and comparative analysis of a SARS-associated virus(Isolate BJ01)显示文摘The genome sequence of the Severe Acute Respiratory Syndrome (SARS)-associated virus provides essential information for the identification of pathogen(s), exploration of etiology and evolution, interpretation of transmission and pathogenesis, development of diagnostics, prevention by future vaccination, and treatment by developing new drugs. We report the complete genome sequence and comparative analysis of an isolate (BJ01) of the coronavirus that has been recognized as a pathogen for SARS. The genome is 29725 nt in size and has 11 ORFs (Open Reading Frames). It is composed of a stable region encoding an RNA-dependent RNA polymerase (composed of 2 ORFs) and a variable region representing 4 CDSs (coding sequences) for viral structural genes (the S, E, M, N proteins) and 5 PUPs (putative uncharacterized proteins). Its gene order is identical to that of other known coronaviruses. The sequence alignment with all known RNA viruses places this virus as a member in the family of Coronaviridae. Thirty putative substitutions have been identified by comparative analysis of the 5 SARS- associated virus genome sequences in GenBank. Fifteen of them lead to possible amino acid changes (non-synonymous mutations) in the proteins. Three amino acid changes, with predicted alteration of physical and chemical features, have been detected in the S protein that is postulated to beinvolved in the immunoreactions between the virus and its host. Two amino acid changes have been detected in the Mprotein, which could be related to viral envelope formation. Phylogenetic analysis suggests the possibility of non-human origin of the SARS-associated viruses but provides noevidence that they are man-made. Further efforts should focus on identifying the etiology of the SARS-associated virus and ruling out conclusively the existence of otherpossible SARS-related pathogen(s). | QIN E'de ZHU Qingyu YU Man FAN Baochang CHANG Guohui SI Bingyin YANG Bao PENG Wenming JIANG Tao LIU Bohua DENG Yongqiang LIU Hong ZHANG Yu WANG Cui LI Yuquan GAN Yonghua LI Xiaoyu L Fushuang TAN Gang CAO Wuchun, YANG Ruifu Institute of Microbiology and Epidemiology, Chinese Academy of Military Medical Sciences, Beijing 100071, China WANG Jian, LI Wei, XU Zuyuan, LI Yan, WU Qingfa, LIN Wei, CHEN Weijun, TANG Lin, DENG Yajun, HAN Yujun, LI Changfeng, LEI Meng, LI Guoqing, LI Wenjie, L Hong, SHI Jianping, TONG Zongzhong, ZHANG Feng, LI Songgang, LIU Bin, LIU Siqi, DONG Wei, WANG Jun, Gane K-S Wong, YU Jun & YANG Huanming* Beijing Genomics Institute, Chinese Academy of Sciences, Beijing 101300 National Center for Genome Information, Beijing 101300, China | 2003 | Chinese Science Bulletin2003，48，10： | 121 |
| 2 | NLRP3-dependent pyroptosis is required for HIV-1 gp120- induced neuropathology显示文摘The human immunodeficiency virus-1(HIV-1)envelope protein gp120 is the major contributor to the pathogenesis of HIVassociated neurocognitive disorder(HAND).Neuroinflammation plays a pivotal role in gp120-induced neuropathology,but how gp120 triggers neuroinflammatory processes and subsequent neuronal death remains unknown.Here,we provide evidence that NLRP3 is required for gp120-induced neuroinflammation and neuropathy.Our results showed that gp120-induced NLRP3-dependent pyroptosis and IL-1βproduction in microglia.Inhibition of microglial NLRP3 inflammasome activation alleviated gp120-mediated neuroinflammatory factor release and neuronal injury.Importantly,we showed that chronic administration of MCC950,a novel selective NLRP3 inhibitor,to gp120 transgenic mice not only attenuated neuroinflammation and neuronal death but also promoted neuronal regeneration and restored the impaired neurocognitive function.In conclusion,our data revealed that the NLRP3 inflammasome is important for gp120-induced neuroinflammation and neuropathology and suggest that NLRP3 is a potential novel target for the treatment of HAND. | Xiaolong He Weijun Yang Zhijie Zeng Yi Wei Jie Gao Bao Zhang Li Li Liqun Liu Yu Wan Qing Zeng Zelong Gong Liting Liu Hanyun Zhang Yubin Li Shaojie Yang Tongtong Hu Lixian Wu Eliezer Masliah Shenghe Huang Hong Cao | 2020 | Cellular & Molecular Immunology2020，17，3： | 11 |
| 3 | NbN superconducting nanowire single photon detector with efficiency over 90% at 1550 nm wavelength operational at compact cryocooler temperature显示文摘The rapid development of superconducting nanowire single-photon detectors over the past decade has led to numerous advances in quantum information technology. The record for the best system detection efficiency at an incident photon wavelength of 1550 nm is 93%. This performance was attained from a superconducting nanowire single-photon detector made of amorphous WSi; such detectors are usually operated at sub-Kelvin temperatures. In this study, we first demonstrate superconducting nanowire single-photon detectors made of polycrystalline NbN with system detection efficiency of 90.2% for 1550-nm-wavelength photons at2.1 K, accessible with a compact cryocooler. The system detection efficiency saturated at 92.1% when the temperature was lowered to 1.8 K. We expect the results lighten the practical and high performance superconducting nanowire single-photon detectors to quantum information and other high-end applications. | WeiJun Zhang LiXing You Hao Li Jia Huang ChaoLin Lv Lu Zhang XiaoYu Liu JunJie Wu Zhen Wang XiaoMing Xie | 2017 | Science China(Physics,Mechanics & Astronomy)2017，60，12： | 9 |
| 4 | Endothelial CDS2 deficiency causes VEGFA-mediated vascular regression and tumor inhibition显示文摘The response of endothelial cells to signaling stimulation is critical for vascular morphogenesis,homeostasis and function.Vascular endothelial growth factor-a(VEGFA)has been commonly recognized as a pro-angiogenic factor in vertebrate developmental,physiological and pathological conditions for decades.Here we report a novel finding that genetic ablation of CDP-diacylglycerol synthetase-2(CDS2),a metabolic enzyme that controls phosphoinositide recycling,switches the output of VEGFA signaling from promoting angiogenesis to unexpectedly inducing vessel regression.Live imaging analysis uncovered the presence of reverse migration of the angiogenic endothelium in cds2 mutant zebrafish upon VEGFA stimulation,and endothelium regression also occurred in postnatal retina and implanted tumor models in mice.In tumor models,CDS2 deficiency enhanced the level of tumorsecreted VEGFA,which in-turn trapped tumors into a VEGFA-induced vessel regression situation,leading to suppression of tumor growth.Mechanistically,VEGFA stimulation reduced phosphatidylinositol(4,5)-bisphosphate(PIP2)availability in the absence of CDS2-controlled-phosphoinositide metabolism,subsequently causing phosphatidylinositol(3,4,5)-triphosphate(PIP3)deficiency and F0X01 activation to trigger regression of CDS2-null endothelium.Thus,our data indicate that the effect of VEGFA on vasculature is context-dependent and can be converted from angiogenesis to vascular regression. | Wencao Zhao Le Cao Hanru Ying Wenjuan Zhang Dantong Li Xiaolong Ziiu Wenzhi Xue Shuang Wu Mengye Cao Cong Fu Haonan Qi Yimei Hao Yun-Chi Tang Jun Qin Tao PZhong Xiaoxi Lin Luyang Yu Xuri Li Lin Li Dianqing Wu Weijun Pan | 2019 | Cell Research2019，29，11： | 9 |
| 5 | Changes in biodiversity and ecosystem function during the restoration of a tropical forest in south china显示文摘Tropical forests continue to vanish rapidly,but few long-term studies have ever examined if and how the lost forests can be restored.Based on a 45-year restoration study in south China,we found that a tropical rain forest,once completely destroyed,could not recover naturally without deliberate restoration efforts.We identified two kinds of thresholds that must be overcome with human ameliorative measures before the ecosystem was able to recover.The first threshold was imposed primarily by extreme physical conditions such as exceedingly high surface temperature and impoverished soil,while the second was characterized by a critical level of biodiversity and a landscape context that accommodates dispersal and colonization processes.Our three treatment catchments(un-restored barren land,single-species plantation,and mixed-forest stand)exhibited dramatically different changes in biodiversity and ecosystem functioning over 4 decades.The mixed forest,having the highest level of biodiversity and ecosystem functioning,possesses several major properties of tropical rain forest.These findings may have important implications for the restoration of many severely degraded or lost tropical forest ecosystems. | REN Hai,LI ZhiAn,SHEN WeiJun,YU ZuoYue,PENG ShaoLin,LIAO ChongHui,DING MingMao & WU JianGuo 1 South China Botanical Garden,Chinese Academy of Sciences,Guangzhou 510650,China 2 Institute of Ecology and Evolution,Zhongshan University,Guangzhou 510275,China 3 Guangdong Institute of Entomology,Guangzhou 510275,China 4 School of Life Sciences and Global Institute of Sustainability,Arizona State University,Tempe,AZ 85287,USA | 2007 | Science China(Life Sciences)2007，50，2： | 9 |
| 6 | Lipogenesis in myoblasts and its regulation of CTRP6 by AdipoR1/Erk/PPARγ signaling pathway显示文摘在 C2C12 myoblasts 的导致的 lipogenesis 和它的规定仍然保持大部分不清楚。这里,我们发现鸡尾酒 methodcould 显著地通过调整类脂化合物导致 lipogenesis 在 myoblasts 的新陈代谢的基因和 Erk1/2 phosphorylation。同时, CTRP6 的表示和分泌物在宫外的 lipogenesis 期间被增加。而且, CTRP6 击倒下面调整 lipogenic 基因的层次和在早 lipogenic 的 phosphorylated Erk1/2 (p-Erk1/2 ) 上演,而在终端区别的起来调整的 p-Erk1/2。有趣地, CTRP6 siRNA 的效果在 myoblasts 是稀释 byU0126 (一个特殊 p-Erk1/2 禁止者) 。而且, AdipoR1,不是 AdipoR2,首先在有丝分裂的同种细胞的扩大的过程期间作为受体 ofCTRP6 被识别。一起,我们建议 CTRP6 调停通过在 myoblasts 表明小径的 AdipoR1/Erk/PPAR 的宫外的 lipogenesis。我们的调查结果将流轻在小说生物在 myoblast lipogenesis 期间 CTRP6 工作并且提供由 lipogenic regulationin 改进家畜的肉质量的一个有希望的方向骨胳的肌肉 myoblasts。 | Wenjing Wu Yunmei Sun Chen Zhao Cunzhen Zhao Xiaochang Chen Guoqiang Wang Weijun Pang Gongshe Yang | 2016 | Acta Biochimica et Biophysica Sinica2016，48，6： | 9 |
| 7 | Cystathionine-γ-lyase ameliorates the histone demethylase JMJD3-mediated autoimmune response in rheumatoid arthritis显示文摘Cystathionine-γ-lyase(CSE),an enzyme associated with hydrogen sulfide(H2S)production,is an important endogenous regulator of inflammation.Jumonji domain-containing protein 3(JMJD3)is implicated in the immune response and inflammation.Here,we investigated the potential contribution of JMJD3 to endogenous CSE-mediated inflammation in rheumatoid arthritis(RA).Upregulated CSE and JMJD3 were identified in synovial fibroblasts(SFs)from RA patients as well as in the joints of arthritic mice.Knocking down CSE augmented inflammation in IL-1β-induced SFs by increasing JMJD3 expression.In addition,CSE−/−mice with collagen-induced arthritis(CIA)developed severe joint inflammation and bone erosion.Conversely,overexpressing CSE inhibited JMJD3 expression by the transcription factor Sp-1 and was accompanied by reduced inflammation in IL-1β-treated SFs.Furthermore,JMJD3 silencing or the administration of the JMJD3 inhibitor GSK-J4 significantly decreased the inflammatory response in IL-1β-treated SFs,mainly by controlling the methylation status of H3K27me3 at the promoter of its target genes.GSK-J4 markedly attenuated the severity of arthritis in CIA mice.In conclusion,suppressing JMJD3 expression by the transcription factor Sp-1 is likely responsible for the ability of CSE to negatively modulate the inflammatory response and reduce the progression of RA. | Weijun Wu Ming Qin Wanwan Jia Zheng Huang Zhongzheng Li Di Yang Mengwei Huang Chenxi Xiao Fen Long Jianchun Mao Philip K.Moore Xinhua Liu Yi Zhun Zhu | 2019 | Cellular & Molecular Immunology2019，16，8： | 9 |
| 8 | White Matter Deficits Underlying the Impaired Consciousness Level in Patients with Disorders of Consciousness显示文摘In this study, we aimed to(1) identify white matter(WM) deficits underlying the consciousness level in patients with disorders of consciousness(DOCs) using diffusion tensor imaging(DTI), and(2) evaluate the relationship between DTI metrics and clinical measures of the consciousness level in DOC patients. With a cohort of 8 comatose, 8 unresponsive wakefulness syndrome/vegetative state, and 14 minimally conscious state patients and 25 patient controls, we performed group comparisons of the DTI metrics in 48 core WM regions of interest(ROIs), and examined the clinical relevance using correlation analysis. We identified multiple abnormal WM ROIs in DOC patients compared with normal controls, and the DTI metrics in these ROIs were significantly correlated with clinical measures of the consciousness level. Therefore, our findings suggested that multiple WM tracts are involved in the impaired consciousness levels in DOC patients and demonstrated the clinical relevance of DTI for DOC patients. | Xuehai Wu Jiaying Zhang Zaixu Cui Weijun Tang Chunhong Shao Jin Hu Jianhong Zhu Yao Zhao Lu Lu Gang Chen Georg Northoff Gaolang Gong Ying Mao Yong He | 2018 | Neuroscience Bulletin2018，34，4： | 8 |
| 9 | Mutation of kri1l causes definitive hematopoiesis failure via PERK-dependent excessive autophagy induction显示文摘 | Xiao-E Jia Ke Ma Tao Xu Lei Gao Shuang Wu Cong Fu Wenjuan Zhang Zhizhang Wang Kaiyu Liu Mei Dong Changbin Jing Chunguang Ren Zhiwei Dong Yi Chen Yi Jin Qiuhua Huang Xing Chang Min Deng Li Li Lingfei Luo Jun Zhu Yongjun Dang Hung-Chun Chang Leonard I Zon Yi Zhou Saijuan Chen Weijun Pan | 2015 | Cell Research2015，25，8： | 8 |
| 10 | Neuroimage-Based Consciousness Evaluation of Patients with Secondary Doubtful Hydrocephalus Before and After Lumbar Drainage显示文摘Hydrocephalus is often treated with a cerebrospinal fluid shunt(CFS) for excessive amounts of cerebrospinal fluid in the brain.However,it is very difficult to distinguish whether the ventricular enlargement is due to hydrocephalus or other causes,such as brain atrophy after brain damage and surgery.The non-trivial evaluation of the consciousness level,along with a continuous drainage test of the lumbar cistern is thus clinically important before the decision for CFS is made.We studied 32 secondary mild hydrocephalus patients with different consciousness levels,who received T1 and diffusion tensor imaging magnetic resonance scans before and after lumbar cerebrospinal fluid drainage.We applied a novel machine-learning method to find the most discriminative features from the multi-modal neuroimages.Then,we built a regression model to regress the JFK Coma Recovery Scale-Revised(CRS-R) scores to quantify the level of consciousness.The experimental results showed that our method not only approximated the CRS-R scores but also tracked the temporal changes in individual patients.The regression model has high potential for the evaluation of consciousness in clinical practice. | Jiayu Huo Zengxin Qi Sen Chen Qian Wang Xuehai Wu Di Zang Tanikawa Hiromi Jiaxing Tan Lichi Zhang Weijun Tang Dinggang Shen | 2020 | Neuroscience Bulletin2020，36，9： | 7 |
| 11 | Effects of chemical modification on physicochemical properties and adsorption behavior of sludge-based activated carbon显示文摘This study aimed to explore the adsorption performance of sludge-based activated carbon(SBC)towards dissolved organic matters(DOMs)removal from sewage,and investigated the modification effect of different types of chemicals on the structure of synthesized SBC.Waste activated sludge(WAS)was used as a carbon source,and HCl,HNO 3,and Na OH were used as different types of chemicals to modify the SBC.With the aid of chemical activation,the modified SBC showed higher adsorption performances on DOMs removal with maximum adsorption of 29.05 mg/g and second-order constant(k)of 0.1367(L/mol/sec)due to the surface elution of ash and minerals by chemicals.The surface elemental composition of MSBC suggested that the content of C-C and C-O functional groups on the surface of modified sludge-based activated carbon(MSBC)played an important role on the adsorption capacities of MSBC towards DOMs removal in sewage.Additionally,the residual molecular weight of DOMs in sewage was investigated using a 3-dimension fluorescence excitationemission matrix(3 D-EEM)and high-performance size exclusion chromatography(HP-SEC).Results showed that the chemical modification significantly improved the adsorption capacity of MSBC on humic acids(HA)and aromatic proteins(APN),and both of Na OH-MSBC and HCl-MSBC were effective for a wide range of different AMW DOMs removal from sewage,while the HNO 3-MSBC exhibited poorly on AMW organics of 2,617 Da and 409 Da due to the reducing content of macropore.In brief,this study provides reference values for the impact of the chemicals of the activation stage before the SBCs application. | Chunxu Wu Lanfeng Li Hao Zhou Jing Ai Hongtao Zhang Jialin Tao Dongsheng Wang Weijun Zhang | 2021 | Journal of Environmental Sciences2021，33，2： | 7 |
| 12 | Characteristics of Upper Mantle Activity in the South China Sea Region and the Indochina Mantle Plume显示文摘According to computed results of the mantle traction field beneath the lithosphere based on satellite-modelled gravity anomalies of different degrees, it has been revealed that the three types of mantle convection on different scales existing in the South China Sea region is the key factor controlling the geodynamics. The mantle convection models on large and middle scales have been proved by natural seismic S-wave tomographic data and interpreted by using the present mantle plume concept In consideration of other relevant geological and geophysical data, the authors put emphasis on discussing the expression form, origin and age of the Indochina mantle plume and its important effect on the conversion of organic matter and hydrocarbon accumulation in Cenozoic basins. | WU Nengyou ZENG Weijun LI Zhenwu CHEN Yizhong WEN Xiwen DU Deli LI Guosheng | 1999 | Acta Geologica Sinica(English Edition)1999，73，4： | 6 |
| 13 | Characteristics of deformation and stress distribution of small coa pillars under leading abutment pressure显示文摘Based on the engineering project on a small coal pillar of 12,521 working face roadway in Xieqiao Coalmine, data regarding surface displacements of the coal pillar, deep displacements and mining stress have been collected and analyzed. The results show that macroscopic transverse fractures of the inner coal pillar are developed within 2–4 m of the roadway surface, which is located outside the coal pillar anchorage zone. There is a displacement of 530 mm at the monitoring point in the 6 m deep zone of the pillar. Transfer of the fracture zone is found in a small coal pillar and the fractures within 3–4 m of the coal-rock zone from the roadway surface undergo propagation and closure of cracks which means this fracture zone is transferred from 3–4 m outside the roadway to only 2–3 m from the roadway surface. In the monitoring zone, vertical and horizontal stresses increase with a feature that shows that acceleration in the deep zone of the pillar is greater than that in the shallow zone. Furthermore, the acceleration of vertical stress is also greater than that of horizontal stress with a peak value in the 4 m zone.The research findings provide a reference for the regulation of a reasonable width of coal pillar in coalmines and optimal control design of surrounding rock. | Wu Hai Zhang Nong Wang Weijun Zhao Yiming Cao Peng | 2015 | International Journal of Mining Science and Technology2015，25，6： | 6 |
| 14 | An option for green and sustainable future: Electrochemical conversion of ammonia into nitrogen显示文摘Green and sustainable options are needed to ease the current energy and environmental crisis, and alleviate the greenhouse effect and energy shortage. As an alternative carbon–neutral synthetic fuel, ammonia shows great potential due to its high energy density, non-toxic by-products, and mature related infrastructures. However, related practical applications have been severely hampered on ammoniaoxidation due to the high cost of catalysts and immature energy utilization systems. Here, we comprehensively summarized the efforts which have been made in recent years with the aim of providing a deep sight into the development and deficiencies in this territory and trying to establish a simple framework of basic knowledge for researchers. The exploration of mechanism is discussed first and then the relevant catalysts studied in recent years are summarized. Besides, the progress of direct ammonia fuel cells(DAFCs) is also presented and the challenges as well as perspectives on future developments of electrocatalysts for ammonia electro-oxidation and its practical application are provided at the end. | Bo Zhou Nana Zhang Yujie Wu Weijun Yang Yanbing Lu Yanyong Wang Shuangyin Wang | 2021 | Journal of Energy Chemistry2021，30，9： | 5 |
| 15 | Atmospheric fine particles in a typical coastal port of Yangtze River Delta显示文摘In recent decades, coastal ports have experienced rapid development and become an important economic and ecological hub in China. Atmospheric particle is a research hotspot in atmospheric environmental sciences in inland regions. However, few studies on the atmospheric particle were conducted in coastal port areas in China, which indeed suffers atmospheric particle pollution. Lack of the physicochemical characteristics of fine particles serves as an obstacle toward the accurate control for air pollution in the coastal port area in China. Here, a field observation was conducted in an important coastal port city in Yangtze River Delta from March 6 to March 19, 2019. The average PM2.5 concentration was 63.7 ±27.8 μg/m^3 and NO3^-, SO4^2-, NH4^+, and organic matter accounted for ?60% of PM 2.5. Fe was the most abundant trace metal element and V as the ship emission indicator was detected. Transmission electron microscopy images showed that SK-rich, soot, Fe, SK-soot and SK-Fe were the major individual particles in the coastal port. V and soluble Fe were detected in sulfate coating of SK-Fe particles. We found that anthropogenic emissions, marine sea salt, and secondary atmosphere process were the major sources of fine particles. Backward trajectory analysis indicated that the dominant air masses were marine air mass, inland air mass from northern Zhejiang and inland-marine mixed air mass from Shandong and Shanghai during the sampling period. The findings can help us better understand the physicochemical properties of atmospheric fine particles in the coastal port of Eastern China. | Qi Yuan Xiaomi Teng Shaoxuan Tu Binxin Feng Zhiyu Wu Hang Xiao Qiuliang Cai Yinxiao Zhang Qiuhan Lin Zhaoce Liu Mengmeng He Xiaokun Ding Weijun Li | 2020 | Journal of Environmental Sciences2020，32，12： | 4 |
| 16 | The emission inventory of atmospheric industrial pollution sources of the five cities in Zhejiang Province显示文摘The amount of several air pollutants emitted in some cities including Hangzhou,Ningbo,Huzhou,Shaoxing and Jiaxing of Zhejiang Province is based on pollution source census data of Zhejiang Province in 2010.This paper focused on the release of air pollutants such as NO_(x2),SO_2,CO,PM2.5,PM10 and VOC,and calculated the total amount of those air pollutants.It analyzed air pollutant emission factors and found that the electricity and heat production industry released the largest amount of pollutants. | Jian Wu Chen Wen Lin Yi Weijun Wang | 2014 | Chinese Journal of Population,Resources and Environment2014，12，2： | 3 |
| 17 | Predicting the Results of RNA Molecular Specific Hybridization Using Machine Learning显示文摘Ribonucleic acid(RNA)hybridization is widely used in popular RNA simulation software in bioinformatics.However limited by the exponential computational complexity of combin atorial problems,it is challenging to decide,within an acceptable time,whether a specific RNA hybridization is effective.We hereby introduce a machine learning based technique to address this problem.Sample machine learning(ML)models tested in the training phase include algorithms based on the boosted tree(BT)random forest(RF),decision tree(DT)and logistic regression(LR),and the corresponding models are obtained.Given the RNA molecular coding training and testing sets,the trained machine learning models are applied to predict the classification of RNA hybridization results.The experiment results show that the op timal predictive accuracies are 96.2%,96.6%,96.0%and 69.8%for the RF,BT,DT and LR-based approaches,respectively,un der the strong constraint condition,compared with traditiona representative methods.Furthermore,the average computation efficiency of the RF,BT,DT and LR-based approaches are208679,269756,184333 and 187458 times higher than that o existing approach,respectively.Given an RNA design,the BT based approach demonstrates high computational efficiency and better predictive accuracy in determining the biological effective ness of molecular hybridization. | Weijun Zhu Xiaokai Liu Mingliang Xu Huanmei Wu | 2019 | IEEE/CAA Journal of Automatica Sinica2019，6，6： | 3 |
| 18 | The Distribution of Petroleum Resources and Characteristics of Main Petroliferous Basins along the Silk Road Economic Belt and the 21st-Century Maritime Silk Road显示文摘The Silk Road Economic Belt and the 21st-century Maritime Silk Road Initiative,abbreviated as the Belt and Road Initiative,is a primary development strategy of China's future international cooperation.Especially,the energy resource cooperation,including oil and gas resources cooperation,is an important part of this initiative.The Belt and Road has undergone complicated geological evolution,and contains abundant mineral resources such as oil,gas,coal,uranium,iron,copper,gold and manganese ore resources.Among these,Africa holds 7.8% of the world's total proven oil reserves.The oil and gas resources in Africa are relatively concentrated,with an overall low exploration degree and small consumption demand.Nigeria and Libya contain the most abundant oil resources in Africa,accounting for 2.2%and 2.9%of the world's total reserves,respectively.Nigeria and Algeria hold the richest natural gas resources in Africa,occupying 2.8%and 2.4%of the world's total reserves,respectively.Africa's oil and gas resources are mainly concentrated in Egypt,Sultan and Western Sahara regions in the northern Africa,and the Gulf of Guinea,Niger River and Congo River area in the western Africa.The Russia-Central Asia area holds rich petroleum resources in Russia,Kazakhstan,Turkmenistan and Uzbekistan.The potential oil and gas areas include the West Siberia Basin,East Siberia Basin and sea continental shelf in Russia,the northern and central Caspian Basin in Kazakhstan,the right bank of the Amu-Darya Basin,the East Karakum uplift and the South Caspian Basin in Turkmenistan,and the Amu-Daria Basin,Fergana Basin,Afghan-Tajik Basin and North Ustyurt Basin in Uzbekistan.The Middle East oil and gas resources are mainly distributed in the Zagros foreland basin and Arabian continental margin basin,and the main oil-producing countries include Saudi Arabia,Iran and Iraq.The Asia Pacific region is a new oil and gas consumption center,with rapid growth of oil and gas demand.In 2012,this region consumed about 33.6%of the world's total oil consumption and 18.9%of the world's total natural gas consumption,which has been ranked the world's largest oil and gas consumption center.The oil and gas resources are concentrated in China,Indosinian,Malaysia,Australia and India.The abundant European proven crude oil reserves are in Norway,Britain and Denmark and also rich natural gas resources in Norway,Holland and Britain.Norway and Britain contain about 77.5%of European proven oil reserves,which accounts for only 0.9%of the world's proven reserves.The Europe includes main petroliferous basins of the Voring Basin,Anglo-Dutch Basin,Northwest German Basin,Northeast German-Polish Basin and Carpathian Basin.According to the analysis of source rocks,reservoir rocks,cap rocks and traps for the main petroliferous basins,the potential oil and gas prospecting targets in the Belt and Road are mainly the Zagros Basin and Arabic Platform in the Middle East,the East Barents Sea Basin and the East Siberia Basin in Russia-Central Asia,the Niger Delta Basin,East African rift system and the Australia Northwest Shelf.With the development of oil and gas theory and exploration technology,unconventional petroleum resources will play an increasingly important role in oil and gas industry. | HAO Qingqing ZUO Yinhui LI Lintao CHEN Weijun YI Junjie WU Lei | 2017 | Acta Geologica Sinica(English Edition)2017，91，4： | 3 |
| 19 | Experimental Gaussian Boson sampling显示文摘Gaussian Boson sampling(GBS) provides a highly efficient approach to make use of squeezed states from parametric down-conversion to solve a classically hard-to-solve sampling problem. The GBS protocol not only significantly enhances the photon generation probability, compared to standard Boson sampling with single photon Fock states, but also links to potential applications such as dense subgraph problems and molecular vibronic spectra. Here, we report the first experimental demonstration of GBS using squeezed-state sources with simultaneously high photon indistinguishability and collection efficiency.We implement and validate 3-, 4- and 5-photon GBS with high sampling rates of 832, 163 and 23 kHz,respectively, which is more than 4.4, 12.0, and 29.5 times faster than the previous experiments.Further, we observe a quantum speed-up on a NP-hard optimization problem when comparing with simulated thermal sampler and uniform sampler. | Han-Sen Zhong Li-Chao Peng Yuan Li Yi Hu Wei Li Jian Qin Dian Wu Weijun Zhang Hao Li Lu Zhang Zhen Wang Lixing You Xiao Jiang Li Li Nai-Le Liu Jonathan P.Dowling Chao-Yang Lu Jian-Wei Pan | 2019 | Science Bulletin2019，64，8： | 3 |
| 20 | An acoustic imaging system of migration technique used in borehole显示文摘以便检测 casing 地上凿穿的损坏,有一个二维的超声的数组的一个声学的成像方法被介绍。数组的每个元素独立地在超声的波浪下面射出,所有元素收到的回响被取样并且在地面表面上传给一台计算机,动态移植方法在此被用来形成一 2 或在地上凿穿的状况的 3-dimensional 图象。数字模拟和实验被进行与在数组使用的元素的一个小数字表明高成像精确性。自从在传统的分阶段执行的数组成像使用的延期电路,系统不在这个系统被需要,并且所有数据进程能在地上凿穿在一个扎根的系统,复杂性和系统的卷被完成可以显著地被简化,它对地上凿穿仪器批评。 | LIN Weijun WU Nan SUN Jian ZHANG Hailan | 2008 | Chinese Journal of Acoustics2008，27，3： | 3 |
您所在的机构暂未开通此部分的功能，请联系管理员