|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Epidemiological characteristics of thyroid nodules and risk factors for malignant nodules: a retrospective study from 6 304 surgical cases显示文摘 | Huan Qin Wang Kun Lou Fuchen Zhang Li Huang Qingxian Han Yunfeng Sun Hancheng Zhu Lei Lin Peng Song Jun Liu Fuqiang Wang Qian Hou Weikai | 2014 | Chinese Medical Journal2014，，12： | 20 |
| 2 | Three-Phase Microstructure Topology Optimization of Two-Dimensional Phononic Bandgap Materials Using Genetic Algorithms显示文摘The bandgap,an important characteristic of the periodic structure,is dispersionrelated,which can be designed by tailoring the layout of materials within the periodic microstructures.A typical example of a periodic structure is phononic crystals (PnCs),which are traditionally fabricated from two-phase materials.Herein,we investigate the topologies of periodic three-phase PnCs.The microstructures of the three-phase PnCs are optimized using a two-stage genetic algorithm,and three case studies are proposed to obtain the following:(1)the maximum relative bandgap width,(2)the maximum absolute bandgap width,and (3)the max- imum bandgap at a specified frequency.More importantly,the three-phase material provides significant advantages compared to the typical two-phase materials,such as a low-frequency bandgap.This research is expected to contribute highly to vibration and noise isolation,elastic wave filters,and acoustic devices. | WeiKai Xu Jinying Ning Meng Zhang Wei Wang Tianzhi Yang | 2018 | Acta Mechanica Solida Sinica2018，31，6： | 4 |
| 3 | Emission Characteristics of VOCs from Automobile Coating Industry in Chongqing City显示文摘To fully analyze emission characteristics of volatile organic compounds( VOCs) from automobile coating industry in Chongqing City,related enterprises in the city were investigated in detail. The results show that the emission of VOCs from the automobile industry in Chongqing City was approximately 20 000 t in 2012,and the contribution rate of automobile coating was 83%. Most VOCs discharged from automobile coating industry were mainly from the use of coatings,diluents,curing agents and other materials containing VOCs. During the process of automobile coating,VOCs were mainly produced during the processes of spraying and drying. Besides,VOCs are partly produced during the processes of mixing paint,gluing,waxing,and repairing. The major ingredients of VOCs discharged during the process of automobile coating were methylbenzene,dimethylbenzene,trimethylbenzene,cumene,ethyl acetate,butyl alcohol,n-butyl alcohol,isobutyl alcohol,formaldehyde,butanone,acetone,cyclohexanone,and methyl ethyl ketone. Besides,the ingredients of naphtha and aromatic hydrocarbon in VOCs need to be determined. The maximum ozone formation potential( OFP) of the above pollutants by the typical enterprises was 900-1 300 mg/m^3. The production of secondary organic aerosol( SOA) was 3 636-11 073 t/a,which didn't include the contribution of aldehydes,ketones,ethers and esters to SOA. This research could provide scientific reference for the establishment of emission standard,control technology and management methods of VOCs from automobile coating industry that accord with economic and social development in Chongqing City. | Zhou Zhi'en Fang Weikai Luo Qian Wang Xiaochen Wu Liping | 2017 | Meteorological and Environmental Research2017，8，3： | 3 |
| 4 | Elevational patterns of carbon,nitrogen and phosphorus in understory bryophytes on the eastern slope of Gongga Mountain,China显示文摘Aims The nutrient uptake,requirement and releasing rates of bryophytes are very different from those of tracheophytes.However,it is diffi-cult to make a quantitative evaluation of bryophytes’roles in nu-trient cycling and their specific eco-physiological adaptations due to lack of knowledge of their concentrations and stoichiometric ratios of carbon(C),nitrogen(N)and phosphorus(P).To fill this gap,the present study aims to investigate:(i)what are the elevational trends of C,N and P concentrations and stoichiometric ratios of bryophytes?(ii)whether C,N and P concentrations and stoichio-metric ratios of bryophytes differ between different bryophyte types(in terms of the growth form and living substrate)?and(iii)how do the exponent scalings of N and P of bryophytes change along the elevational gradient?Methods We measured and calculated the C,N,P concentrations and stoi-chiometric ratios of bryophytes from four elevations on the eastern slope of Gongga Mountain(22 species in total).Differences in these traits among elevations,and between different bryophyte types were compared.The log-log allometric regression parameters of N and P at each elevation were also determined and compared.Important Findings The C,N and P concentrations of bryophytes showed decreasing trends with increasing elevations.More specifically,erect bryo-phytes possessed higher C and N concentrations than those of pros-trate species,and terricolous species had higher P concentration than that of corticolous and saxicolous species.Bryophytes from different elevations had an invariant allometric regression slope for P versus N.Future research at a larger scale is in need for a more generalized law of bryophytes. | Zhe Wang Chunyan Pi Xiaoming Li Weikai Bao | 2019 | Journal of Plant Ecology2019，12，4： | 3 |
| 5 | Identifying EGFR-Expressed Cells and Detecting EGFR Multi-Mutations at Single-Cell Level by Microfluidic Chip显示文摘EGFR mutations companion diagnostics have been proved to be crucial for the efficacy of tyrosine kinase inhibitor targeted cancer therapies. To uncover multiple mutations occurred in minority of EGFR-mutated cells,which may be covered by the noises from majority of unmutated cells, is currently becoming an urgent clinical requirement. Here we present the validation of a microfluidic-chip-based method for detecting EGFR multimutations at single-cell level. By trapping and immunofluorescently imaging single cells in specifically designed silicon microwells, the EGFR-expressed cellswere easily identified. By in situ lysing single cells, the cell lysates of EGFR-expressed cells were retrieved without cross-contamination. Benefited from excluding the noise from cells without EGFR expression, the simple and cost-effective Sanger's sequencing, but not the expensive deep sequencing of the whole cell population, was used to discover multi-mutations. We verified the new method with precisely discovering three most important EGFR drugrelated mutations from a sample in which EGFR-mutated cells only account for a small percentage of whole cell population. The microfluidic chip is capable of discovering not only the existence of specific EGFR multi-mutations,but also other valuable single-cell-level information: on which specific cells the mutations occurred, or whether different mutations coexist on the same cells. This microfluidic chip constitutes a promising method to promote simple and cost-effective Sanger's sequencing to be a routine test before performing targeted cancer therapy. | Ren Li Mingxing Zhou Jine Li Zihua Wang Weikai Zhang Chunyan Yue Yan Ma Hailin Peng Zewen Wei Zhiyuan Hu | 2018 | Nano-Micro Letters2018，10，1： | 2 |
| 6 | miR?142?3p promotes osteoblast differentiation by modulating Wnt signaling显示文摘 | Weihua Hu Yaping Ye Weikai Zhang Jiang Wang Anmin Chen Fengjing Guo | 2013 | Molecular Medicine Reports2013，，2： | 2 |
| 7 | Two Ultraviolet Radiation Datasets that Cover China显示文摘Ultraviolet(UV) radiation has significant effects on ecosystems, environments, and human health, as well as atmospheric processes and climate change. Two ultraviolet radiation datasets are described in this paper. One contains hourly observations of UV radiation measured at 40 Chinese Ecosystem Research Network stations from 2005 to 2015. CUV3 broadband radiometers were used to observe the UV radiation, with an accuracy of 5%, which meets the World Meteorology Organization's measurement standards. The extremum method was used to control the quality of the measured datasets. The other dataset contains daily cumulative UV radiation estimates that were calculated using an all-sky estimation model combined with a hybrid model. The reconstructed daily UV radiation data span from 1961 to 2014. The mean absolute bias error and root-mean-square error are smaller than 30% at most stations, and most of the mean bias error values are negative, which indicates underestimation of the UV radiation intensity. These datasets can improve our basic knowledge of the spatial and temporal variations in UV radiation. Additionally, these datasets can be used in studies of potential ozone formation and atmospheric oxidation, as well as simulations of ecological processes. | Hui LIU Bo HU Yuesi WANG Guangren LIU Liqin TANG Dongsheng JI Yongfei BAI Weikai BAO Xin CHEN Yunming CHEN Weixin DING Xiaozeng HAN Fei HE Hui HUANG Zhenying HUANG Xinrong LI Yan LI Wenzhao LIU Luxiang LIN Zhu OUYANG Boqiang QIN Weijun SHEN Yanjun SHEN Hongxin SU Changchun SONG Bo SUN Song SUN Anzhi WANG Genxu WANG Huimin WANG Silong WANG Youshao WANG Wenxue WEI Ping XIE Zongqiang XIE Xiaoyuan YAN Fanjiang ZENG Fawei ZHANG Yangjian ZHANG Yiping ZHANG Chengyi ZHAO Wenzhi ZHAO Xueyong ZHAO Guoyi ZHOU Bo ZHU | 2017 | Advances in Atmospheric Sciences2017，34，7： | 2 |
| 8 | Biomechan-ical analysis of unilateral fixation with interbody cages显示文摘 | Chen Hsiangho Cheung Hunghsueh Wang Weikai | | 0，，04： | 1 |
| 9 | Nitrogen and phosphorus translocation of forest floor mosses as affected by a pulse of these nutrients显示文摘藓类是亚高山森林、北方针叶林和极地苔原等原始生态系统的重要组成部分。养分沉降是这些生态系统的主要养分来源。然而,对藓类如何利用大气沉降这一时间上异质性较高的养分来源的认识缺乏,限制了我们对藓类在生态系统养分循环中作用的认识,也制约了模拟和预测生态系统服务功能动态变化的有效性。本研究中,我们重点关注如下问题:(1)藓类新生部分的氮、磷含量随氮或磷沉降量的变化;(2)氮或磷养分沉降如何影响藓类的氮磷转运;(3)氮磷转运与藓类新生部分养分含量的关联性?为此,我们在位于青藏高原东部的亚高山冷杉林中开展了设置有不同氮、磷施加量水平的突发养分沉降实验。以林下优势度最高的塔藓和锦丝藓为对象,我们在施加实验处理8天和1年后,分别测定了不同年龄藓类茎段中的氮、磷含量。研究结果发现,养分处理8天后,锦丝藓和塔藓的所有茎段的氮或磷含量均随处理中氮或磷施加量的增加而增加,表明它们能够高效率地吸收施加的氮或磷。养分处理1年后,形成于养分处理后的新生茎段中的氮、磷含量以及氮磷比与处理后8天的藓类茎段中氮、磷含量以及氮磷比呈正相关关系,表明藓类将吸收的养分转运至新生部分,转运过程受源—库关系的调控。磷转运效率解释了新生茎段21%-23%的氮磷比变化,而氮转运与新生茎段氮磷比没有显著关系,结果暗示磷转运对藓类生长的重要性。上述结果表明,养分转运是藓类植物利用间断的沉降养分的关键机制,也使藓类成为生态系统中重要的养分库。 | Xin Liu Zhe Wang Xiaoming Li Weikai Bao | 2020 | Journal of Plant Ecology2020，13，5： | 1 |
| 10 | Research Progress of Continuous Blood Purification in the Treatment of Severe Sepsis in Children显示文摘Pediatric sepsis is the most common disease in pediatric critical illness,because the main reason for the disease is that children's immune level is not high or the immune system is not perfect,when children's lung,abdominal cavity and blood system are infected,it will cause systemic inflammation and immune dysfunction.Early clinical symptoms are mainly irregular and intermittent fever.When the disease develops to severe sepsis,the children will suffer from acute heart failure,oliguria,respiratory alkalosis and even multiple organ failure.The incidence of death is high.It is reported that the incidence rate of sepsis in children can reach 0.3%,and the mortality rate is 50%.High incidence rate,high mortality rate and high treatment cost are the biggest problems in the pediatric field.In the past,the clinical hope of clearing away heat and toxin,promoting blood circulation and removing stasis,strengthening inflammation and other methods in traditional Chinese medicine,but the treatment effect is not ideal.With the improvement of modem medical understanding of sepsis,continuous blood purification therapy is introduced into the treatment of children with severe sepsis.In order to further explore the effect of continuous blood purification in the treatment of children with severe sepsis,the author summarizes the clinical practice experience and relevant literature,hoping to provide reference for relevant medical staff。 | Weikai Wang Yun Du Aiqin Cheng Shunli Liu Lin Wei Jianna Li Yirong Wang Li Wang | 2021 | Journal of Clinical and Nursing Research2021，5，3： | 1 |
| 11 | Multi-objective optimization of layered elastic metamaterials with multiphase microstructures显示文摘 | XU Weikai WANG Wei YANG Tianzhi | 2013 | Journal of Vibration and Acoustics2013，135，04： | 1 |
| 12 | Perfor- mance of DCSK cooperative communication systems over multipath fading channels 显示文摘 | Xu Weikai WANG Lin CHEN Guanrong | 2011 | IEEE Transac- tions on Circuits and Systems I: Regular Papers2011，58，1： | 1 |
| 13 | Discussion about Environmental Impact Assessment of Shale Gas Development显示文摘China is the third country to develop and utilize shale gas after the United States and Canada. However,shale gas development has significant environmental problems,such as huge consumption of both land and water resources,water pollution risk of hydraulic fracturing,leakage risk of shale gas and so on. At present,environmental impact assessment of shale gas development in China has been conducted based on the Technical Guideline for Environmental Impact Assessment——Constructional Project of Petroleum and Natural Gas Development on Land which lacks clear guidance on selection and quantitative analysis of pollution factors. In this paper,based on the experience of shale gas development in America,special environmental problems that need to be noticed for shale gas development were summarized,and the supplement to the technical guideline for environmental impact assessment of shale gas development was discussed to improve the environmental impact assessment system. | Zhou Zhi en Fang Weikai Song Dan Chen Min Luo Qian Wang Xiaochen | 2016 | Meteorological and Environmental Research2016，7，5： | 1 |
| 14 | Fabrication and characterization of polymer composites surface coated F e3 O 4/ MWCNT s hybrid buckypaper as a novel microwave‐absorbing structure显示文摘 | Shaowei Lu Keming Ma Xiaoqiang Wang Xuhai Xiong Weikai Xu Caixia Jia | 2015 | J. Appl. Polym. Sci2015，，： | 1 |
| 15 | Double knock-in pig models with elements of binary Tet-On and phiC31 integrase systems for controllable and switchable gene expression显示文摘Inducible expression systems are indispensable for precise regulation and in-depth analysis of biological process.Binary Tet-On system has been widely employed to regulate transgenic expression by doxycycline.Previous pig models with tetracycline regulatory elements were generated through random integration.This process often resulted in uncertain expression and unpredictable phenotypes,thus hindering their applications.Here,by precise knock-in of binary Tet-On 3G elements into Rosa26 and Hipp11 locus,respectively,a double knock-in reporter pig model was generated.We characterized excellent properties of this system for controllable transgenic expression both in vitro and in vivo.Two att P sites were arranged to flank the td Tomato to switch reporter gene.Single or multiple gene replacement was efficiently and faithfully achieved in fetal fibroblasts and nuclear transfer embryos.To display the flexible application of this system,we generated a pig strain with Dox-inducing h KRASexpression through phiC31 integrase-mediated cassette exchange.After eight months of Dox administration,squamous cell carcinoma developed in the nose,mouth,and scrotum,which indicated this pig strain could serve as an ideal large animal model to study tumorigenesis.Overall,the established pig models with controllable and switchable transgene expression system will provide a facilitating platform for transgenic and biomedical research. | Qin Jin Xiaoyu Yang Shixue Gou Xiaoyi Liu Zhenpeng Zhuang Yanhui Liang Hui Shi Jiayuan Huang Han Wu Yu Zhao Zhen Ouyang Quanjun Zhang Zhaoming Liu Fangbing Chen Weikai Ge Jingke Xie Nan Li Chengdan Lai Xiaozhu Zhao Jiaowei Wang Meng Lian Lei Li Longquan Quan Yinghua Ye Liangxue Lai Kepin Wang | 2022 | Science China(Life Sciences)2022，65，11： | 1 |
| 16 | The C:N:P stoichiometry in bryophytes:relationships with habitat,climate and growth form显示文摘The elemental composition and stoichiometry of organisms provide a useful lens for explaining and predicting ecological paterns and processes.However,few studies have focused on stoichiometry in bryophytes,even though they are abundant in many pristine ecosystems.Several case studies found variable paterns in bryophyte stoichiometry(e.g.[1,2]). | Xin Liu Zhe Wang Xiaoming Li Weikai Bao Kathrin Rousk | 2023 | National Science Review2023，10，4： | 0 |
| 17 | Desorption hysteresis of coalbed methane and its controlling factors: a brief review显示文摘Most coal reservoirs show high gas content with relatively low desorption efficiency,which restricts the efficiency of coalbed methane(CBM)extraction and single-well productivity.This review highlights the desorption hysteresis mechanism and its controlling factors as well as methods and models to reveal desorption hysteresis and potential solutions.Methane adsorption and desorption can be recorded by both gravimetric and volumetric experiments.Although different adsorption models are used,desorption is generally considered with the Langmuir model.Desorption hysteresis is influenced by the petrophysical composition,thermal maturity,pore structure distribution of the coal,reservoir temperature,and moisture and water content.Methods for calculating desorption hysteresis include the area index,hysteresis index and introduction of a hysteresis factor and a hysteresis coefficient.Molecular dynamics simulations of methane desorption are mainly based on theories of kinetics,thermodynamics,and potential energy.The interaction forces operating among coal,water,and methane molecules can be calculated from microscopic intermolecular forces(van der Waals forces).The desorption hysteresis mechanism and desorption process still lack quantitative probe methodologies,and future research should focus on coal wettability under the constraints of liquid content,potential energy adjustment mechanism,and quantitative analysis of methane desorption rates.Further research is expected to reveal the desorption kinetics of methane through the use of the solid–liquid–gas three-phase coupling theory associated with the quantitative analysis of methane desorption hysteresis,thereby enhancing the recovery rate and efficiency of CBM wells. | Weikai XU Junhui LI Xiang WU Du LIU Zhuangsen WANG | 2021 | Frontiers of Earth Science2021，15，2： | 0 |
| 18 | Non-structural carbohydrate levels of three co-occurring understory plants and their responses to forest thinning by gap creation in a dense pine plantation显示文摘We investigated non-structural carbohydrates(NSC) levels and components(starch,glucose,fructose and sucrose) in the leaves of three typical co-occurring forestfloor plants,moss Eurhynchium savatieri(ES),fern Parathelypteris nipponica(PN) and forb Aruncus sylvester(AS) in a 30-year-old Chinese pine(Pinus tabulaeformis)plantation forest on the eastern Tibetan Plateau.We also explored their responses to three gap creation treatments(control and two gap creations of 80 and 110 m2) based on NSC levels.PN had the highest leaf NSC level of the three plants,with AS second and ES lowest.Starch was the predominant component of NSC and the contents of glucose were higher than those of fructose or sucrose for all three species.The NSC level of ES in intermediate gaps was significantly higher than at control sites.PN also had higher NSC levels in both small and intermediate gaps than in control sites.But the differences between treatments were not obvious for AS.Our results suggest that ES and PN benefit from gap formation while the two species have different NSC response sensitivities to gap size,but the leaf NSC level of AS is less sensitive to the disturbance. | Zhe Wang Weikai Bao Xiaoli Yan | 2015 | Journal of Forestry Research2015，26，2： | 0 |
| 19 | Overview of the LAMOST survey in the first decade显示文摘The Large Sky Area Multi-Object Fiber Spectroscopic Telescope(LAMOST),also known as the Guoshoujing Telescope,is a major national scientific facility for astronomical research located in Xinglong,China.Beginning with a pilot survey in 2011,LAMOST has been surveying the night sky for more than 10 years.The LAMOST survey covers various objects in the Universe,from normal stars to peculiar ones. | Hongliang Yan Haining Li Song Wang Weikai Zong Haibo Yuan Maosheng Xiang Yang Huang Jiwei Xie Subo Dong Hailong Yuan Shaolan Bi Yaoquan Chu Xiangqun Cui Licai Deng Jianning Fu Zhanwen Han Jinliang Hou Guoping Li Chao Liu Jifeng Liu Xiaowei Liu Ali Luo Jianrong Shi Xuebing Wu Haotong Zhang Gang Zhao Yongheng Zhao | 2022 | The Innovation2022，3，2： | 0 |
| 20 | Research on the Performance of Titanium Gypsum Concrete Based on Calcium-Silicon-Sulfur Ratio显示文摘Based on the high sulfur content in titanium gypsum,the concept of the calcium-silicon-sulfur(Ca/Si/S)ratio was proposed.The Ca/Si/S ratio of concrete was adjusted by changing the titanium gypsum,fly ash,and cement con-tent.The effects of different Ca/Si/S ratios on the mechanical properties,hydration products,and concrete micro-structure were investigated by nuclear magnetic resonance,uniaxial compression,and scanning electron microscopy.The result shows:(1)The compressive strength of concrete mixed with titanium gypsum increases first and then decreases with the Ca/Si/S ratio decrease.When the Ca/Si/S ratio is 1:0.85:0.10,the strength reaches the peak and is lower than the blank group.(2)The microstructure indicates the addition of titanium gypsum can effectively stimulate the activity of fly ash.Still,too much or too little titanium gypsum will hamper concrete strength development.(3)Titanium gypsum concrete’s nuclear magnetic resonance T2 spectrum has two characteristic peaks.With the Ca/Si/S ratio decreasing,the micropores in the concrete expand towards the macropores.The compressive strength is negatively correlated with the proportion of macropores and is positively correlated with the proportion of no-capillary pores. | Lixia Guo Weikai Wang Ling Zhong Yuhang Guo | 2023 | Journal of Renewable Materials2023，11，1： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员