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| 1 | In vivo theranostics with near-infraredemitting carbon dots—highly efficient photothermal therapy based on passive targeting after intravenous administration显示文摘Carbon dots that exhibit near-infrared fluorescence(NIR CDs)are considered emerging nanomaterials for advanced biomedical applications with low toxicity and superior photostability and targeting compared to currently used photoluminescence agents.Despite progress in the synthesis of NIR CDs,there remains a key obstacle to using them as an in vivo theranostic agent.This work demonstrates that the newly developed sulfur and nitrogen codoped NIR CDs are highly efficient in photothermal therapy(PTT)in mouse models(conversion efficiency of 59%)and can be readily visualized by photoluminescence and photoacoustic imaging.The real theranostic potential of NIR CDs is enhanced by their unique biodistribution and targeting.Contrary to all other nanomaterials that have been tested in biomedicine,they are excreted through the body’s renal filtration system.Moreover,after intravenous injection,NIR CDs are accumulated in tumor tissue via passive targeting,without any active species such as antibodies.Due to their accumulation in tumor tissue without the need for intratumor injection,high photothermal conversion,excellent optical and photoacoustic imaging performance,and renal excretion,the developed CDs are suitable for transfer to clinical biomedical practice. | Xin Bao Ye Yuan Jingqin Chen Bohan Zhang Di Li Ding Zhou Pengtao Jing Guiying Xu Yingli Wang Kateřina Holá Dezhen Shen Changfeng Wu Liang Song Chengbo Liu Radek Zbořil Songnan Qu | 2018 | Light(Science & Applications)2018，7，1： | 13 |
| 2 | Rifaximin Alters Intestinal Bacteria and Prevents Stress-Induced Gut Inflammation and Visceral Hyperalgesia in Rats显示文摘 | Dabo Xu Jun Gao Merritt Gillilland Xiaoyin Wu Il Song John Y. Kao Chung Owyang | 2014 | Gastroenterology2014，，2： | 4 |
| 3 | ETB and epidermal growth factor receptor stimulation of wound closure in bovine corneal epithelial cells显示文摘 | Tao WH Gregory IL Wu XP | 1995 | Invest Ophthalmol Vis Sci1995，36，： | 2 |
| 4 | Colorectal neoplasm in asymptomatic Asians: a prospective multinational multicenter colonoscopy survey显示文摘 | Jeong-Sik Byeon Suk-Kyun Yang Tae Il Kim Won Ho Kim James Y.W. Lau Wai-Keung Leung Rikiya Fujita Govind K. Makharia Murdan Abdullah Ida Hilmi Jose Sollano Khay-Guan Yeoh Deng-Chyang Wu Min Hu Chen Pradermchai Kongkam Joseph J.Y. Sung | 2007 | Gastrointestinal Endoscopy2007，，： | 2 |
| 5 | Treatment with high-dose methylprednisolone for hepatic veno-occlusive disease in a child with rhabdomyosarcoma显示文摘 | Chen IL Yang SN Hsiao CC Wu KS Sheen JM | 2008 | Pediatr Neonatol2008，49，4： | 1 |
| 6 | Phase I study of weekly docetaxel and cisplatin concurrent with thoracic radiotherapy in stage III non-small-cell lung cancer显示文摘 | Hong-Gyun Wu Yung-Jue Bang Eun Kyung Choi Yong Chan Ahn Young Whan Kim Tae-Hwan Lim Cheolwon Suh Keunchil Park Charn Il Park | 2002 | International Journal of Radiation Oncology Biology Physics2002，，1： | 1 |
| 7 | Microbial production of a poly (γ-glutamic acid) derivative by Bacillus subtilis显示文摘 | Shih IL Wu PJ Shieh CJ | 2005 | Process Biochemistry2005，40，8： | 1 |
| 8 | Less patient discomfort by one -man colonoscopy examination 显示文摘 | Lee IL Wu CS | 2006 | Int J Clin Pract2006，60，6： | 1 |
| 9 | IL-10 and IL-4 suppress cytokine synthesis by different mechanisms显示文摘 | Wang P Wu P Siegel MI Interleukin (IL)-10 inhibits nuclear factor kappa B (NF kappa B) activation in human monocytes | 1995 | J-Biol-Chem1995，270，16： | 1 |
| 10 | A model for implementing BPR based on strategic perspectives: an empirical study 显示文摘 | Wu IL | 2002 | Information & Management2002，39，1： | 1 |
| 11 | Toddaquinoline from formosan Toddalia asiatica显示文摘 | Chen IS Tsai IL Wu S J | 1993 | Phytochemistty1993，34，5： | 1 |
| 12 | Significance of cardiactroponin I and creatine kitlase release after coronary intervention 显示文摘 | Wu CJ Liang ~IL Chiou KR | 2001 | Zhonghua Yi Xue Za Zhi!i Taipei)2001，64，6： | 1 |
| 13 | An Extension of Trust and TAM Model with TPB in the Initial Adoption of On-line Tax: An Empirical Study 显示文摘 | Wu IL | 2005 | International Journal of Human-Computer Studies2005，62，6： | 1 |
| 14 | Predictive role of nuclear factorkappaB activity in gastric cancer:a promising adjuvant approach with caffeic acid phenethyl ester显示文摘 | Wu CS Chen MF Lee IL | 2007 | J Clin Gastroenterol2007，41，10： | 1 |
| 15 | GMI, an immunomodulatoryprotein from Ganoderma microsporum, induces autophagy in non-small cell lung caiu^er cells 显示文摘 | Hsin IL Ou CC Wu TC | 2011 | Autophagy2011，7，8： | 1 |
| 16 | Calcitonin in the treatment ofosteoporotic pain 显示文摘 | Yang HZ Kuang J Wu W il | 2001 | Chinese Journal of New Drugs and ClinicalMedicine2001，20，1： | 1 |
| 17 | Less patient discomfort by one-man colonoscopy examination 显示文摘 | Lee IL Wu CS | 2006 | Int J Clin Pract2006，60，6： | 1 |
| 18 | Variants of stretchactivated two-pore potassium channel TREK-1 associated with preterm labor in humans显示文摘 | Wu YY Singer CA Buxton IL | 2012 | Biol Reprod2012，87，4： | 1 |
| 19 | Effects of the aqueous extract of Schizandra chinensis fruit on ethanol withdrawal-induced anxiety in rats显示文摘 | Wu Yiyan Zhao Zhenglin Yang Yupeng Yang Xudong Eun Young Jang Nathan D Schilaty David M Hedges Sang Chan Kim Il Je Cho Zhao Rongjie | 2014 | Chinese Medical Journal2014，，10： | 1 |
| 20 | Paclitaxel induced apop to sis in human gast ric care oma cell lines显示文摘 | L IL L WU CW el al | 1996 | Cancer1996，77，14： | 1 |
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