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| 1 | Production of Two Elite Glutinous Rice Varieties by Editing Wx Gene显示文摘The waxy gene(Wx) in rice, which encodes the granule bound starch synthase enzyme, is responsible for amylose synthesis. Glutinous(sticky) rice has little or no amylose that can be used in various applications, such as brewing. In this study, knockout of the Wx gene with CRISPR/Cas9 technology was conducted in two elite japonica rice lines, Huaidao 5(HD5) and Suken 118(SK118), aiming to develop elite sticky rice varieties. We achieved six homozygous T_0 plants with more than 200 bp deletion in the Wx gene, as well as 36 wx-HD5 and 18 wx-SK118 homozygous transgene-free plants in the T_1 generation. The seeds of all the mutants were white and opaque, similar to those of sticky rice, and contained only 2.6%–3.2% amylose. Results of scanning electron microscopy showed that the quality of rice did not change. In conclusion, we successfully developed two elite sticky rice varieties. | FEI Yunyan YANG Jie WANG Fangquan FAN Fangjun LI Wenqi WANG Jun XU Yang ZHU Jinyan ZHONG Weigong | 2019 | Rice science2019,26,2: | 6 |
| 2 | Novel constant-cladding tapered-core ytterbium-doped fiber for high-power fiber laser oscillator显示文摘Power scaling based on traditional ytterbium-doped fibers(YDFs)is limited by optical nonlinear effects and transverse mode instability(TMI)in high-power fiber lasers.Here,we propose a novel long tapered fiber with a constant cladding and tapered core(CCTC)along its axis direction.The tapered-core region of the fiber is designed to enhance the stimulated Raman scattering(SRS)threshold and suppress higher-order mode resonance in the laser cavity.The CCTC YDF was fabricated successfully with a modified chemical vapor deposition(MCVD)method combined with solution doping technology,which has a cladding diameter of 400µm and a varying core with a diameter of~24μm at both ends and~31μm in the middle.To test the performance of the CCTC fiber during high-power operation,an all-fiber laser oscillator based on a CCTC YDF was investigated experimentally.As a result,a maximum output power of 3.42 kW was achieved with an optical-to-optical efficiency of 55.2%,although the TMI effect was observed at an output power of~3.12 kW.The measured beam quality(M^(2)factor)was~1.7,and no sign of the Raman component was observed in the spectrum.We believe that CCTC YDF has great potential to simultaneously mitigate the SRS and TMI effects,and further power scaling is promising by optimizing the structure of the YDF. | Yun Ye Xianfeng Lin Xiaoming Xi Chen Shi Baolai Yang Hanwei Zhang Xiaolin Wang Jinyan Li Xiaojun Xu | 2021 | High Power Laser Science and Engineering2021,9,2: | 5 |
| 3 | Geniposide, the component of the Chinese herbal formula Tongluojiunao, protects amyloid-β peptide(1–42)-mediated death of hippocampal neurons via the non-classical estrogen signaling pathway显示文摘Tongluojiunao(TLJN) is an herbal medicine consisting of two main components, geniposide and ginsenoside Rg1. TLJN has been shown to protect primary cultured hippocampal neurons. However, its mechanism of action remains unclear. In the present study, primary cultured hippocampal neurons treated with Aβ1–42(10 μmol/L) significantly increased the release of lactate dehydrogenase, which was markedly reduced by TLJN(2 μL/mL), specifically by the component geniposide(26 μmol/L), but not ginsenoside Rg1(2.5 μmol/L). The estrogen receptor inhibitor, ICI182780(1 μmol/L), did not block TLJN- or geniposide-mediated decrease of lactate dehydrogenase under Aβ1–42-exposed conditions. However, the phosphatidyl inositol 3-kinase or mitogen-activated protein kinase pathway inhibitor, LY294002(50 μmol/L) or U0126(10 μmol/L), respectively blo cked the decrease of lactate dehydrogenase mediated by TLJN or geniposide. Therefore, these results suggest that the non-classical estrogen pathway(i.e., phosphatidyl inositol 3-kinase or mitogen-activated protein kinase) is involved in the neuroprotective effect of TLJN, specifically its component, geniposide, against Aβ1–42-mediated cell death in primary cultured hippocampal neurons. | Jiao Li Feng Wang Haimin Ding Chunyan Jin Jinyan Chen Yanan Zhao Xiaojing Li Wenju Chen Ping Sun Yan Tan Qi Zhang Xu Wang Angran Fan Qian Hua | 2014 | Neural Regeneration Research2014,9,5: | 3 |
| 4 | Phase-and epidemic region-adjusted estimation of the number of coronavirus disease 2019 cases in China显示文摘The outbreak of the coronavirus disease 2019 in China was first reported in Wuhan in December 2019 and gradually spread to other areas in China.After implementation of prevention and control measures,the estimation of the epidemic trend is needed.A phase-and region-adjusted SEIR model was applied for modeling and predicting the number of cases in Wuhan,Hubei Province and regions outside Hubei Province in China.The estimated number of infections could reach its peak in late February 2020 in Wuhan and Hubei Province,which is 55303–84520 and 83944–129312,respectively,while the epidemic peaks in regions outside Hubei Province in China could appear on February 13,2020 with the estimated 13035–19108 cases.According to the estimation,the outbreak would abate in March and April all over China.Current estimation provided evidence for planned work resumption under stringent prevention and control in China to further support the fight against the epidemic.Nevertheless,there is still possibility of the second outbreak brought by the work resumption and population migration,especially from Hubei Province and high intensity cities outside Hubei Province.Strict prevention and control measures still need to be considered in the regions with high intensity of epidemic and densely-populated cities. | Ruijie Chang Huwen Wang Shuxian Zhang Zezhou Wang Yinqiao Dong Lhakpa Tsamlag Xiaoyue Yu Chen Xu Yuelin Yu Rusi Long Ning-Ning Liu Qiao Chu Ying Wang Gang Xu Tian Shen Suping Wang Xiaobei Deng Jinyan Huang Xinxin Zhang Hui Wang Yong Cai | 2020 | Frontiers of Medicine2020,14,2: | 2 |
| 5 | Scalp acupuncture Yikang therapy on Baihui(GV20),Sishencong(EX-HN1),Zhisanzhen,Niesanzhen improves neurobehavior in young rats with cerebral palsy through Notch signaling pathway显示文摘OBJECTIVE:To investigate the efficacy of scalp acupuncture Yikang therapy on Baihui(GV20),Sishencong(EX-HN1),Zhisanzhen,Niesanzhen,on neurobehavior in young rats with cerebral palsy based on Notch signaling pathway.METHODS:Thirty 7-day-old rats were randomly divided into sham,model and acupuncture,10 rats in each group.The cerebral palsy model was established by the accepted modeling method,the acupuncture group selected'Baihui(GV20)','Sishencong(EX-HN1)','Zhisanzhen'and'Niesanzhen'for intervention 24 h after the model was made.The body masses were recorded before and after the treatment,respectively.After the intervention,the rats were subjected to suspension experiment,slope experiment,tactile stimulation experiment and Morris water maze experiment.After the end of the experiment,the morphological changes of hippocampal histology were observed by hematoxylineosin(HE)staining under light microscope,and the expression of Notch1,Notch3 and Hes5 were detected by Western blot and quantitative real-time polymerase chain reaction(PCR).RESULTS:The changes in body mass of the rats in each group were different;in behavioral experiments,compared with the sham,the suspension time of the model was shortened,the slope experiment,tactile stimulation experiment,and escape latency time were prolonged,and the number of platform crossing was reduced in the model,compared with the model,the suspension time of the acupuncture was prolonged,the slope experiment,tactile stimulation experiment,and escape latency time were shortened,and the number of platform crossing times was increased;HE staining showed severe hippocampal damage in the model and reduced hippocampal damage in the acupuncture.Western Blot and real-time fluorescence quantitative PCR showed that the expression of Notch1,Notch3 and Hes5 were increased in the model and the expression of Notch1,Notch3,Hes5 in acupuncture were decreased.CONCLUSIONS:Scalp acupuncture Yikang therapy may improve neurobehavior and reduce brain injury in rats with cerebral palsy by downregulating the expression of Notch1,Notch3,and Hes5. | XUE Jianyi XU Jinyan HUANG Mao YU Wentao YAN Yihui YAN Yuanjie YIN Zhenjin LU Qian PENG Wanying YAN Siyang | 2023 | Journal of Traditional Chinese Medicine2023,43,2: | 1 |
| 6 | The solvability of the multidimensional TLS problem显示文摘 | Xu Lingling Fan Jinyan Huang Kaibin | 1998 | Numer Math J of Chin Uni1998,7,2: | 1 |
| 7 | Cost-Effectiveness of Payments for Ecosystem Services with Dual Goals of Environment and Poverty Alleviation显示文摘 | Crystal Gauvin Emi Uchida Scott Rozelle Jintao Xu Jinyan Zhan | 2010 | Environmental Management2010,,: | 1 |
| 8 | Efficient Semi‑Transparent Wide‑Bandgap Perovskite Solar Cells Enabled by Pure‑Chloride 2D‑Perovskite Passivation显示文摘Wide-bandgap(WBG)perovskite solar cells suffer from severe non-radiative recombination and exhibit relatively large opencircuit voltage(V_(OC))deficits,limiting their photovoltaic performance.Here,we address these issues by in-situ forming a well-defined 2D perovskite(PMA)_(2)PbCl_(4)(phenmethylammonium is referred to as PMA)passivation layer on top of the WBG active layer.The 2D layer with highly pure dimensionality and halide components is realized by intentionally tailoring the side-chain substituent at the aryl ring of the post-treatment reagent.First-principle calculation and single-crystal X-ray diffraction results reveal that weak intermolecular interactions between bulky PMA cations and relatively low cation-halide hydrogen bonding strength are crucial in forming the well-defined 2D phase.The(PMA)_(2)PbCl_(4)forms improved type-I energy level alignment with the WBG perovskite,reducing the electron recombination at the perovskite/hole-transport-layer interface.Applying this strategy in fabricating semi-transparent WBG perovskite solar cells(indium tin oxide as the back electrode),the V_(OC)deficits can be reduced to 0.49 V,comparable with the reported state-of-the-art WBG perovskite solar cells using metal electrodes.Consequently,we obtain hysteresis-free 18.60%-efficient WBG perovskite solar cells with a high V_(OC)of 1.23 V. | Liu Yang Yongbin Jin Zheng Fang Jinyan Zhang Ziang Nan Lingfang Zheng Huihu Zhuang Qinghua Zeng Kaikai Liu Bingru Deng Huiping Feng Yujie Luo Chengbo Tian Changcai Cui Liqiang Xie Xipeng Xu Zhanhua Wei | 2023 | Nano-Micro Letters2023,15,8: | 1 |
| 9 | Younger patients with chronic lymphocytic leukemia benefit from rituximabtreatment: A single center study in China显示文摘 | Zhenshu Xu Jinyan Zhang Shunquan Wu Zhihong Zheng Zhizhe Chen Rong Zhan | 2013 | Oncology Letters2013,,4: | 1 |
| 10 | Effect of change in an inhibitory neurotransmitter of the myenteric plexus on the pathogenetic mechanism of irritable bowel syndrome subgroups in rat models显示文摘 | Jun Rong Xu JinYan Luo Lei Shang | 2006 | Chinese J Digest Dis2006,7,2: | 1 |
| 11 | Microcalorimetric study of the toxic effect of selenium on the mitochondrial metabolism of cyprinus carpio liver显示文摘 | Chunying Chen Yi Liu Jinyan Zhou Huibi Xu Songsheng Qü | 1997 | Biological Trace Element Research (-)1997,,1: | 1 |
| 12 | Controlled growth of ZnO nanorods by polymer template and their photoluminescence properties显示文摘A large amount of one-dimensional ZnO nanorods with diameters in 15―50 nm aligned in radial cluster were successfully synthesized by polar polymer polyvinyl alcohol (PVA) as soft-template. The growth of ZnO nanorods was controlled by changing annealing temperature. The evolution of the morphology and microstructure was investigated by scanning electron microscope, transmission electron micro- scope and X-ray diffraction. It is shown that ZnO nanorods tend to be uniform and the crystallization is gradually improved with the temperature increasing from 400℃ to 700℃. The photoluminescence spectra of products show a strong ultra violet emission and relatively weak defect emissions. The sharp strong emission peak at 354 nm owing to the inter-band transition indicates the extraordinary photoluminescence property of ZnO nanorods. | LI JiangYong LI Lan XU JianPing ZHANG XiaoSong LI HaiYan ZHUANG JinYan | 2009 | Science China(Technological Sciences)2009,52,4: | 1 |
| 13 | Insights into the architecture of human-induced polygenic selection in Duroc pigs显示文摘Background:As one of the most utilized commercial composite boar lines,Duroc pigs have been introduced to China and undergone strongly human-induced selection over the past decades.However,the efficiencies and limitations of previous breeding of Chinese Duroc pigs are largely understudied.The objective of this study was to uncover directional polygenic selection in the Duroc pig genome,and investigate points overlooked in the past breeding process.Results:Here,we utilized the Generation Proxy Selection Mapping(GPSM)on a dataset of 1067 Duroc pigs with 8,766,074 imputed SNPs.GPSM detected a total of 5649 putative SNPs actively under selection in the Chinese Duroc pig population,and the potential functions of the selection regions were mainly related to production,meat and carcass traits.Meanwhile,we observed that the allele frequency of variants related to teat number(NT)relevant traits was also changed,which might be influenced by genes that had pleiotropic effects.First,we identified the direction of selection on NT traits by G,and further pinpointed large-effect genomic regions associated with NT relevant traits by selection signature and GWAS.Combining results of NT relevant traits-specific selection signatures and GWAS,we found three common genome regions,which were overlapped with QTLs related to production,meat and carcass traits besides“teat number”QTLs.This implied that there were some pleiotropic variants underlying NT and economic traits.We further found that rs346331089 has pleiotropic effects on NT and economic traits,e.g.,litter size at weaning(LSW),litter weight at weaning(LWW),days to 100 kg(D100),backfat thickness at 100 kg(B100),and loin muscle area at 100 kg(L100)traits.Conclusions:The selected loci that we identified across methods displayed the past breeding process of Chinese Duroc pigs,and our findings could be used to inform future breeding decision. | Zitao Chen Jinyan Teng Shuqi Diao Zhiting Xu Shaopan Ye Dingjie Qiu Zhe Zhang Yuchun Pan Jiaqi Li Qin Zhang Zhe Zhang | 2023 | Journal of Animal Science and Biotechnology2023,14,1: | 0 |
| 14 | Analysis of the abnormal resistance in AlGaN/GaN heterostructure's ohmic contact tests显示文摘Ti/Al/Ti/Au and Ti/Al/Ni/Au ohmic contacts were fabricated on AlGaN/GaN heterostructure under different temperatures of rapid thermal processing (RTP). Since abnormal resistance values were observed during the contact resis-tance testing,the surface morphology and contact borders of the samples were analyzed to determine the physical mecha-nism. Such abnormal phenomenon is found to originate from cracking of the AlGaN layer during RTP,flowing of Ti/Al metallic liquid along the crevices,and continuous reaction of the metallic liquid with AlGaN/GaN. Such processes result in abnormal conduction channels. The possible mechanism of the crevice formation was discussed,and the possible solutions to avoid the crevices were proposed. | XU Chuan WANG Jinyan JIN Haiyan ZHOU Jin WEN Cheng P | 2007 | Rare Metals2007,26,5: | 0 |
| 15 | USP7 deubiquitinates and stabilizes NOTCH1 in T-cell acute lymphoblastic leukemia显示文摘T-cell acute lymphoblastic leukemia(T-ALL)is a highly aggressive leukemia that is primarily caused by aberrant activation of the NOTCH1 signaling pathway.Recent studies have revealed that posttranslational modifications,such as ubiquitination,regulate NOTCH1 stability,activity,and localization.However,the specific deubiquitinase that affects NOTCH1 protein stability remains unestablished.Here,we report that ubiquitin-specific protease 7(USP7)can stabilize NOTCH1.USP7 deubiquitinated NOTCH1 in vivo and in vitro,whereas knockdown of USP7 increased the ubiquitination of NOTCH1.USP7 interacted with NOTCH1 protein in T-ALL cells,and the MATH and UBL domains of USP7 were responsible for this interaction.Depletion of USP7 significantly suppressed the proliferation of T-ALL cells in vitro and in vivo,accompanied by downregulation of the NOTCH1 protein level.Similarly,pharmacologic inhibition of USP7 led to apoptosis of T-ALL cells.More importantly,we found that USP7 was significantly upregulated in human T-ALL cell lines and patient samples,and a USP7 inhibitor exhibited cell cytotoxicity toward primary T-ALL cells,indicating the clinical relevance of these findings.Overall,our results demonstrate that USP7 is a novel deubiquitinase that stabilizes NOTCH1.Therefore,USP7 may be a promising therapeutic target in the currently incurable T-ALL. | Huizhuang Shan Xiangyun Li Xinhua Xiao Yuting Dai Jinyan Huang Junjun Song Meng Liu Li Yang Hu Lei Yin Tong Li Zhou Hanzhang Xu Yingli Wu | 2018 | Signal Transduction and Targeted Therapy2018,3,1: | 0 |
| 16 | Study on the correlation between ambient environment-meteorological factors and the number of visits of acute otitis media,Lanzhou,China显示文摘To investigate the correlation between environmental-meteorological factors and daily visits for acute otitis media(AOM)in Lanzhou,China.Methods:Data were collected in 2014e2016 by the Departments of Otolaryngology-Head and Neck Surgery at two hospitals in Lanzhou.Relevant information,including age,sex and visiting time,was collected.Environmental data included air quality index,PM10,PM2.5,O3,CO,NO2 and SO2,and meteorological data included daily average temperature(T,C),daily mean atmospheric pressure(AP,hPa),daily average relative humidity(RH,%)and daily mean wind speed(W,m/s).The SPSS22.0 software was used to generate Spearman correlation coefficients in descriptive statistical analysis,and the R3.5.0 software was used to calculate relative risk(RR)and to obtain exposure-response curves.The relationship between meteorological-environmental parameters and daily AOM visits was summarized.Results:Correlations were identified between daily AOM visits and CO,O3,SO2,CO,NO2,PM2.5 and PM10 levels.NO2,SO2,CO,AP,RH and T levels significantly correlated with daily AOM visits with a lag exposure-response pattern.The effects of CO,NO2,SO2 and AP on daily AOM visits were significantly stronger compared to other factors(P<0.01).O3,W,T and RH were negatively correlated with daily AOM visits.The highest RR lagged by 3e4 days.Conclusions:The number of daily AOM visits appeared to be correlated with short-term exposure to mixed air pollutants and meteorological factors from 2014 through 2016 in Lanzhou. | Haiyue Tian Baicheng Xu Xinlan Wang Jinyan Wang Cuiping Zhong | 2020 | Journal of Otology2020,15,3: | 0 |
| 17 | Infection Characteristics and Interaction of Three Species of Penicillium in the Postharvest Storage of‘Gonggan'Mandarin(Citrus reticulata)显示文摘[Objectives]This study was conducted to understand the infection characteristics of Penicillium on‘Gonggan’mandarin(Citrus reticulata)and its effects on postharvest storage quality.[Methods]Nine inoculation treatments were designed and tested for the three identified Penicillium species,namely:three single inoculation experiments,four compound inoculation experiments,and two controls without inoculation.After treatment,the fruit was put into plastic film fresh-keeping bags and stored at a natural room temperature.The determined and analyzed indexes included fruit disease incidence,disease index,disease symptoms,disease spot expansion speed and weight loss rate,soluble solid content and organic acid content in different inoculation treatments.[Results]All‘Gonggan’fruit inoculated with Penicillium were diseased 2 d after inoculation,and completely rotted 14 d later.Of the three Penicillium species isolated and identified,Penicillium digitorum and its combinations were the most harmful to‘Gonggan’fruit.The hazard of Penicillium italicum was equal to or even weaker than that of Penicillium expansum.Eventually,P.digitorum dominated when coexisting on the same fruit.Different species of Penicillium obviously showed competition and antagonism in the process of growth and infection,especially for P.digitorum which was stronger,but other two species of Penicillium also had obvious self-protection ability.Low-temperature storage played a crucial role in the preservation of‘Gonggan’fruit,because it could significantly inhibit Penicillium infestation,and suppress fruit weight loss and the reduction of the contents of soluble solids and organic acids.[Conclusions]The infection characteristics and interaction relationship of Penicillium in the postharvest storage of‘Gonggan’fruit were revealed. | Shaoping ZHANG Chengxiang XU Jinyan LAI Yuchan PENG Chunyan ZHONG Minzhi LIANG | 2022 | Agricultural Biotechnology2022,11,3: | 0 |
| 18 | Highly sensitive plasmonic nanorod hyperbolic metamaterial biosensor显示文摘Plasmonic sensing based on nanostructures is a powerful analytical tool for ultrasensitive label-free biomolecule detection that holds great potential in the field of clinical diagnostics and biomedical research.Here,we report the fabrication,the characterization,and the principle of operation of gold nanorod hyperbolic metamaterials(NHMMs) along with ultrasensitive bulk refractive index and label-free biomolecular detection.By combining electron-beam lithography and nanoscale electroplating,we demonstrate the fabrication of a highly ordered,height-controllable,and vertical array of nanorods.By exciting the bulk plasmon–polariton mode in the NHMM using a prism-coupling technique and integrating the sensor in microfluidics,we demonstrate that the bulk sensitivity and figure of merit of our device could reach 41,600 nm/RIU and 416 RIU^(-1),respectively.The physical mechanism of this high bulk sensitivity is revealed through theoretical and experimental studies.Moreover,by bio-functionalizing the surface of the NHMM sensor,monitoring the binding of streptavidin at dilute concentrations is performed in real time.We test different concentrations of streptavidin ranging from 200 to 5 μg/m L,and the NHMM biosensor exhibits a 1 nm wavelength shift for a 5 μg/m L streptavidin detection.By fitting the Hill equation of the NHMM biosensor and taking into account the level of noise(0.05 nm) as the minimum wavelength shift of the detectable limit,the limit of detection of the NHMM biosensor to streptavidin can be estimated to be 0.14 μg/m L(2.4 nm).As a direct comparison,a 0.5 nm wavelength shift for 20 μg/m L of streptavidin is reported when using a conventional gold film sensor under identical experimental conditions.The developed plasmonic NHMM sensor shows tremendous potential for highly sensitive bulk solutions and biomolecule detection and provides a promising avenue for free-label biosensing applications in the future. | RUOQIN YAN TAO WANG XINZHAO YUE HUIMIN WANG YU-HUI ZHANG PENG XU LU WANG YUANDONG WANG JINYAN ZHANG | 2022 | Photonics Research2022,10,1: | 0 |
| 19 | Some Domestic Strontium Carbonate Producers Will Be Beaten out显示文摘1 Surplus capacity and decreasing profit in 2007 With negative impacts from the recession of the color TV picture tube production and the elimination of the export rebate,China’s strontium carbonate manufacturing sector suffered from oversupply in 2007.Many domestic producers cut their operation rates or shifted to producing other chemicals in order to deal with the slack demand,but the price of strontium carbonate still dropped from around RMB4 200 per ton at the be-ginning of 2007 to around RMB3 200 per ton at the end of the year.As the require-ments for saving energy and reducing pol-lutants get higher and higher,producers | Wu Weidong Xu Qing Nanjing Jinyan Strontium Industry Co.,Ltd. | 2008 | China Chemical Reporter2008,,10: | 0 |
| 20 | A systematic survey of LU domain-containing proteins reveals a novel human gene,LY6A,which encodes the candidate ortholog of mouse Ly-6A/Sca-1 and is aberrantly expressed in pituitary tumors显示文摘The Ly-6 and uPAR(LU)domain-containing proteins represent a large family of cell-surface markers.In particular,mouse Ly-6A/Sca-1 is a widely used marker for various stem cells;however,its human ortholog is missing.In this study,based on a systematic survey and comparative genomic study of mouse and human LU domain-containing proteins,we identified a previously unannotated human gene encoding the candidate ortholog of mouse Ly-6A/Sca-1.This gene,hereby named LY6A,reversely overlaps with a lncRNA gene in the majority of exonic sequences.We found that LY6A is aberrantly expressed in pituitary tumors,but not in normal pituitary tissues,and may contribute to tumorigenesis.Similar to mouse Ly-6A/Sca-1,human LY6A is also upregulated by interferon,suggesting a conserved transcriptional regulatory mechanism between humans and mice.We cloned the full-length LY6A cDNA,whose encoded protein sequence,domain architecture,and exon‒intron structures are all well conserved with mouse Ly-6A/Sca-1.Ectopic expression of the LY6A protein in cells demonstrates that it acts the same as mouse Ly-6A/Sca-1 in their processing and glycosylphosphatidylinositol anchoring to the cell membrane.Collectively,these studies unveil a novel human gene encoding a candidate biomarker and provide an interesting model gene for studying gene regulatory and evolutionary mechanisms. | Dan Liu Chunhui Xu Yanting Liu Wen Ouyang Shaojian Lin Aining Xu Yuanliang Zhang Yinyin Xie Qiuhua Huang Weili Zhao Zhu Chen Lan Wang Saijuan Chen Jinyan Huang Zhe Bao Wu Xiaojian Sun | 2023 | Frontiers of Medicine2023,17,3: | 0 |