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| 1 | 2018 Chinese Pediatric Cardiology Society(CPCS) guideline for diagnosis and treatment of syncope in children and adolescents显示文摘Syncope belongs to the transient loss of consciousness(TLOC), characterized by a rapid onset, short duration, and spontaneous complete recovery. It is common in children and adolescents, accounting for 1% to 2% of emergency department visits.Recurrent syncope can seriously affect children's physical and mental health, learning ability and quality of life and sometimes cardiac syncope even poses a risk of sudden death. The present guideline for the diagnosis and treatment of syncope in children and adolescents was developed for guiding a better clinical management of pediatric syncope. Based on the globally recent development and the evidence-based data in China, 2018 Chinese Pediatric Cardiology Society(CPCS) guideline for diagnosis and treatment of syncope in children and adolescents was jointly prepared by the Pediatric Cardiology Society, Chinese Pediatric Society, Chinese Medical Association(CMA)/Committee on Pediatric Syncope, Pediatricians Branch, Chinese Medical Doctor Association(CMDA)/Committee on Pediatric Cardiology, Chinese College of Cardiovascular Physicians, Chinese Medical Doctor Association(CMDA)/Pediatric Cardiology Society, Beijing Pediatric Society, Beijing Medical Association(BMA). The present guideline includes the underlying diseases of syncope in children and adolescents, the diagnostic procedures, methodology and clinical significance of standing test and headup tilt test, the clinical diagnosis vasovagal syncope, postural orthostatic tachycardia syndrome, orthostatic hypotension and orthostatic hypertension, and the treatment of syncope as well as follow-up. | Cheng Wang Yaqi Li Ying Liao Hong Tian Min Huang Xiangyu Dong Lin Shi Jinghui Sun Hongfang Jin Junbao Du Jindou An Jie Chen Mingwu Chen Qi Chen Sun Chen Yonghong Chen Zhi Chen Adolphus Kai-tung Chau Junbao Du Zhongdong Du Junkai Duan Hongyu Duan Xiangyu Dong Lin Feng Lijun Fu Fangqi Gong Yonghao Gui Ling Han Zhenhui Han Bing He Zhixu He Xiufen Hu Yimin Hua Guoying Huang Min Huang Ping Huang Yujuan Huang Hongfang Jin Mei Jin Bo Li Fen Li Tao Li Xiaohui Li Xiaoyan Liu Yan Li Haitao Lv Tiewei Lv Zipu Li Luyi Ma Silin Pan Yusheng Pang Hua Peng Yuming Qin Jie Shen Lin Shi Kun Sun Jinghui Sun Hong Tian Jie Tian Cheng Wang Hong Wang Lei Wang Jinju Wang Wendi Wang Yuli Wang Rongzhou Wu Tianhe Xia Yanyan Xiao Chunhong Xie Yanlin Xing Zhenyu Xiong Baoyuan Xu Yi Xu Hui Yan Shiwei Yang Qijian Yi Xia Yu Xianyi Yu Yue Yuan Hongyan Zhang Huili Zhang Li Zhang Qingyou Zhang Xi Zhang Yanmin Zhang Zhiwei Zhang Cuifen Zhao Bin Zhou Hua Zhu | 2018 | Science Bulletin2018，63，23： | 54 |
| 2 | Therapeutic potential of siRNA-mediated combined knockdown of the lAP genes (Livin, XIAP, and Survivin) on human bladder cancer T24 cells显示文摘Livin, apoptosis (XIAP ) 的 X 连接禁止者,和 Survivin 几乎是 apoptosis 的三个著名禁止者在癌症房间只过去表示并且为癌症治疗被认为有势力目标。在现在的学习,我们发现 Livin, XIAP,和 Survivin 同时在膀胱癌症房间被表示。我们推测了那 Livin, XIAP,和 Survivin 可能在房间生长和 apoptosis 上有 synergistic 效果。我们的结果证实了联合那所有这三基因击倒能 synergistically 禁止增长和高级膀胱癌症 T24 房间的转变能力并且把房间 apoptotic 敏感提升到化疗。而且,联合了 Livin, XIAP,和 Survivin 罐头击倒显著地增加许多活跃 caspase-3,活跃 caspase-7,活跃 caspase-9,和 cytosolic Smac。我们的调查结果暗示 Livin, XIAP,和 Survivin 的那联合 silencing 可以是一个有势力为膀胱癌症的多指向的基因治疗。 | Deyong Yang Xishuang Song Jianing Zhang Lin Ye Shujing Wang Xiangyu Che Jianbo Wang Zhiwei Zhang Lina Wang Wei Shi | 2010 | Acta Biochimica et Biophysica Sinica2010，42，2： | 29 |
| 3 | A hypersonic target coherent integration detection algorithm based on Doppler feedback显示文摘The traversal search of multi-dimensional parameter during the process of hypersonic target echo signal coherent integration,leads to the problem of large amounts of calculation and poor real-time performance.In view of these problems,a modified polynomial Radon-polynomial Fourier transform(MPRPFT)hypersonic target coherent integration detection algorithm based on Doppler feedback is proposed in this paper.Firstly,the Doppler estimation value of the target is obtained by using the target point information obtained by subsequent non-coherent integration detection.Then,the feedback adjustment of the coherent integration process is performed by using the acquired target Doppler estimation value.Finally,the coherent integration is completed after adjusting the search interval of compensation.The simulation results show that the algorithm can effectively reduce the computational complexity and improve the real-time performance on the basis of the effective coherent integration of hypersonic target echo signals. | LI Lin WANG Guohong SUN Dianxing ZHANG Xiangyu | 2020 | Journal of Systems Engineering and Electronics2020，31，1： | 6 |
| 4 | Gravitational wave astrophysics, data analysis and multimessenger astronomy显示文摘This paper reviews gravitational wave sources and their detection. One of the most exciting potential sources of gravitational waves are coalescing binary black hole systems. They can occur on all mass scales and be formed in numerous ways, many of which are not understood. They are generally invisible in electromagnetic waves, and they provide opportunities for deep investigation of Einstein's general theory of relativity. Sect. 1 of this paper considers ways that binary black holes can be created in the universe, and includes the prediction that binary black hole coalescence events are likely to be the first gravitational wave sources to be detected. The next parts of this paper address the detection of chirp waveforms from coalescence events in noisy data.Such analysis is computationally intensive. Sect. 2 reviews a new and powerful method of signal detection based on the GPUimplemented summed parallel infinite impulse response filters. Such filters are intrinsically real time alorithms, that can be used to rapidly detect and localise signals. Sect. 3 of the paper reviews the use of GPU processors for rapid searching for gravitational wave bursts that can arise from black hole births and coalescences. In sect. 4 the use of GPU processors to enable fast efficient statistical significance testing of gravitational wave event candidates is reviewed. Sect. 5 of this paper addresses the method of multimessenger astronomy where the discovery of electromagnetic counterparts of gravitational wave events can be used to identify sources, understand their nature and obtain much greater science outcomes from each identified event. | LEE Hyung Mok LE BIGOT Eric-Olivier DU ZhiHui LIN ZhangXi GUO XiangYu WEN LinQing PHUKON Khun Sang PANDEY Vihan BOSE Sukanta FAN Xi-Long HENDRY Martin | 2015 | Science China(Physics,Mechanics & Astronomy)2015，58，12： | 5 |
| 5 | Recent Development in X-Ray Imaging Technology:Future and Challenges显示文摘X-ray imaging is a low-cost,powerful technology that has been extensively used in medical diagnosis and industrial nondestructive inspection.The ability of X-rays to penetrate through the body presents great advances for noninvasive imaging of its internal structure.In particular,the technological importance of X-ray imaging has led to the rapid development of highperformance X-ray detectors and the associated imaging applications.Here,we present an overview of the recent development of X-ray imaging-related technologies since the discovery of X-rays in the 1890s and discuss the fundamental mechanism of diverse X-ray imaging instruments,as well as their advantages and disadvantages on X-ray imaging performance.We also highlight various applications of advanced X-ray imaging in a diversity of fields.We further discuss future research directions and challenges in developing advanced next-generation materials that are crucial to the fabrication of flexible,low-dose,highresolution X-ray imaging detectors. | Xiangyu Ou Xue Chen Xianning Xu Lili Xie Xiaofeng Chen Zhongzhu Hong Hua Bai Xiaowang Liu Qiushui Chen Lin Li Huanghao Yang | 2021 | Research2021，，1： | 5 |
| 6 | Industrial upgrading based on global innovation chains:A case study of Huawei technologies Co.,Ltd.Shenzhen显示文摘Although China is a global trade power,it has low value-added trade,which lies at the bottom of the global value chain.Therefore,there is an urgent need to change the unfavorable position of the international division of labor in China.The global innovation chain is a new development of innovation through which China can implement open innovation and utilize the world's advanced knowledge,technology,information,and other resources to enhance its innovation capabilities,promote industrial upgrading,and improve the status of its global value chains.This paper takes Huawei as an example of international cooperation and innovation,aspects that have allowed the company to rapidly improve its position and prestige in the industry.The case study of Huawei suggests that China should introduce talent,increase investment abroad,attract foreign investment,expand intellectual property trade,develop outsourcing and international strategic research and development alliances,build a global innovation chain,and promote industrial upgrading to elevate the status of its international division of labor. | Xuejun Lin Bingqian Liu Jiaxu Han Xiangyue Chen | 2018 | International Journal of Innovation Studies2018，2，3： | 5 |
| 7 | Synthesis of Mg-Al-carbonate layered double hydroxide by an atom-economic reaction显示文摘A clean method for preparing layered double hydroxides (LDHs) has been developed, featured by using the hydroxides of two different metals as starting materials by atom-economic reactions. The reactions were carried out under hydrothermal conditions in either a high pressure autoclave or a microwave digester. The compositions, structural parameters and thermal behavior of the resulting LDHs are very similar to those of materials produced by using the separate nucleation and aging steps (SNAS) method. The major advantage of the new method is that no by-product is produced, so that filtration and washing processes are unnecessary. The consequent reduction in water consumption is beneficial to the environment. | Xiangyu Xu Dianqing Li Jiaqing Song Yanjun Lin Zhi Lv Min Wei Xue Duan | 2010 | Particuology2010，8，3： | 4 |
| 8 | Combinational biosynthesis and characterization of a fluorescent 82β-phycocyanin of Spirulina platensis显示文摘To biosynthesize fluorescent Spirulina platensis (Sp)β -phycocyanin (PC) in Escherichia coli, a BLASTP search for homologs of the cpeS gene, a chromophore lyase, was performed against the Synechocystis sp. PCC 6803 (S6) proteome. A highly homologous gene, slr2049, was obtained from the S6 genome. Sites 82 and 153 in -phycocyanin of Sp were modified by site-directed muta- genesis. Two recombinant expression vectors were constructed and transformed into E. coli BL21: (i) pCDF-cpcB (C153A)- slr2049-sll0583-ho1-pcyA; and (ii) pCDF-cpcB (C82I)-slr2049-sll0583-ho1-pcyA. Lyases encoded by the genes slr2049 and sll0583 catalyzed the linking of Sp 82β -PC to phycocyanobilin (PCB), and fluorescent CpcB (C153A)-PCB was generated. We present a strategy for the co-expression of multiple genes in a single expression vector to identify the function of an unknown gene. Recombinant phycobiliproteins produced on a large scale are promising fluorescent tags for diagnostics and pharmacology. | GUAN XiangYu ZHANG WeiJie CHI XiaoYuan LIN HanZhi WANG JinFeng QIN Song | 2012 | Chinese Science Bulletin2012，57，25： | 3 |
| 9 | Theoretical study on rotary-sliding disk triboelectric nanogenerators in contact and non-contact modes显示文摘摩擦电 nanogenerator (TENG ) 作为收获技术的一个新、有效的机械精力出现了。在这个工作,为有栅栏结构的旋转滑动的磁盘 TENG 的一个理论模型被构造,包括 dielectric-to-dielectric 和 conductor-to-dielectric 盒子。有限元素方法(女性) 被利用描绘在接触和非接触模式工作的 rotarysliding 磁盘 TENG 的基本物理。磁盘 TENG 的基本性质被发现被象 tribo 表面间距,栅栏数字,和几何尺寸那样的结构的参数控制。从女性的计算,一种近似 V-Q- 关系通过插值方法被造,然后有任意的负担抵抗的 TENG 动态产量特征是数字地计算的。最后,结构的参数和旋转上的力量和匹配的抵抗评估的输出的相关性被揭示。现在的工作提供旋转滑动的磁盘 TENG 的工作原则的深入的理解并且为在特定的应用程序优化 TENG 输出性能用作重要指导。 | Tao Jiang Xiangyu Chen Keda Yang Changbao Han Wei Tang Zhong Lin Wang | 2016 | Nano Research2016，9，4： | 3 |
| 10 | Influence of extreme weather and meteorological anomalies on outbreaks of influenza A (H1N1)显示文摘Biological experiments and epidemiological evidence indicate that variations in environment have important effect on the occurrence and transmission of epidemic influenza.It is therefore important to understand the characteristic patterns of transmission for prevention of disease and reduction of disease burden.Based on case records,we analyzed the environmental characteristics including climate variables in Changsha,and then constructed a meteorological anomaly susceptive-infective-removal (SIR) model on the basis of the results of influenza A (H1N1) transmission.The results showed that the outbreak of influenza A (H1N1) in Changsha showed significant correlation with meteorological conditions;the spread of influenza was sensitive to meteorological anomalies,and that the outbreak of influenza A (H1N1) in Changsha was influenced by a combination of absolute humidity anomalous weather conditions,contact rates of the influenza patients and changes in population movements.These findings will provide helpful information regarding prevention strategies under different conditions,a fresh understanding of the emergence and re-emergence of influenza outbreaks,and a new perspective on the transmission dynamics of influenza. | XIAO Hong TIAN HuaiYu LIN XiaoLing GAO LiDong DAI XiangYu ZHANG XiXing CHEN BiYun ZHAO Jian XU JingZhe | 2013 | Science China(Technological Sciences)2013，56，3： | 2 |
| 11 | A comprehensive analysis of the Bencao(herbal)small RNA Atlas reveals novel RNA therapeutics for treating human diseases显示文摘Cross-kingdom herbal mi RNA was first reported in 2012.Using a modified herbal extraction protocol,we obtained 73,677,287sequences by RNA-seq from 245 traditional Chinese Medicine(TCM),of which 20,758,257 were unique sequences.We constructed a Bencao(herbal)small RNA(s RNA)Atlas(http://gffzz4a3adbfa122d4a47h06nco6qccuqu69n0.ffgz.tsg.suse.edu.cn),annotated the sequences by sequence-based clustering,and created a nomenclature system for Bencao s RNAs.The profiles of 21,757 mi RNAs in the Atlas were highly consistent with those of plant mi RNAs in mi RBase.Using software tools,our results demonstrated that all human genes might be regulated by s RNAs from the Bencao s RNA Atlas,part of the predicted human target genes were experimentally validated,suggesting that Bencao s RNAs might be one of the main bioactive components of herbal medicines.We established roadmaps for oligonucleotide drugs development and optimization of TCM prescriptions.Moreover,the decoctosome,a lipo-nano particle consisting of 0.5%–2.5%of the decoction,demonstrated potent medical effects.We propose a Bencao(herbal)Index,including small-molecule compounds(SM),protein peptides(P),nucleic acid(N),non-nucleic and non-proteinogenic large-molecule compounds(LM)and elements from Mendeleev's periodic table(E),to quantitatively measure the medical effects of botanic medicine.The Bencao s RNA Atlas is a resource for developing gene-targeting oligonucleotide drugs and optimizing botanical medicine,and may provide potential remedies for the theory and practice of one medicine. | Yinghao Cao Yexuan Lin Na Sun Xinyi Du Yixin Dong Song Mei Xingyu Deng Xiaobei Li Shaoting Guo Kegong Tang Jiaqi Liu Xiangyu Qiao Dandan Zhao Yuhao Qin Cong Zhang Tianyi Xin Xiaohu Shi Congzhao Zhou Tao Dong De-an Guo Benedikt MKessler Dong Xu Jingyuan Song Fengming Huang Xiaoyue Wang Chengyu Jiang | 2023 | Science China(Life Sciences)2023，66，10： | 2 |
| 12 | Validation of MODIS ocean-colour products in the coastal waters of the Yellow Sea and East China Sea显示文摘An extensive study collected in situ data along the Yellow Sea(YS) and East China Sea(ECS) to assess the radiometric properties and the concentration of the water constituents derived from Moderate Resolution Imaging Spectroradiometer(MODIS). Thirteen high quality match-ups were obtained for evaluating the MODIS estimates of Rrs(λ), chlorophyll a(Chl a) and concentrations of suspended particulate sediment matter(SPM). For MODIS Rrs(λ), the mean absolute percentage difference(APD) was in the range of 20%–36%, and the highest uncertainty appeared at 412 nm, whereas the band ratio of Rrs(λ) at 488 nm compared with that at 547 nm was highly consistent, with an APD of 7%. A combination of near-infrared bands and shortwave infrared wavelengths atmosphere correction algorithm(NIR-SWIR algorithm) was applied to the MODIS data, and the estimation accuracy of Rrs were improved at most of the visible spectral bands except 645 nm, 667 nm and 678 nm. Two ocean-colour empirical algorithms for Chl a estimation were applied to the processed data, the results indicated that the accuracy of the derived Chl a values was obviously improved, the four-band algorithms outperformed the other algorithm for measured and simulated datasets, and the minimum APD was 35%. The SPM was also quantified. Two regional and two coastal SPM algorithms were modified according to the in situ data. By comparison, the modified Tassan model had a higher accuracy for the application along the YS and ECS with an APD of 21%. However, given the limited match-up dataset and the potential influence of the aerosol properties on atmosphere correction, further research is required to develop additional algorithms especially for the low Chl a coastal water. | Lingling Jiang Xiangyu Guo Lin Wang Shubha Sathyendranath Hayley Evers-King Yanlong Chen Bingnan Li | 2020 | Acta Oceanologica Sinica2020，39，1： | 2 |
| 13 | Reducing relapse and accelerating osteogenesis in rapid maxillary expansion using an injectable mesoporous bioactive glass/fibrin glue composite hydrogel显示文摘Rapid maxillary expansion(RME),as a common treatment for craniomaxillofacial deformity,faces the challenge of high relapse rates and unsatisfactory therapeutic effects.In this study,a standardized Sprague-Dawley(SD)rat RME model was first established with a modified expander as well as retainer design and optimized anterior maxillary expanding force of 100 g which exerted the most synchronized mobility of mid-palatal suture and incisors.Via the standardized model,the high relapse rate was proven to be attributed to insufficient osteogenesis in expanded suture,requiring long-term retainer wearing in clinical situations.To reduce the relapse rate,mesoporous bioactive glass/fibrin glue(MBG/FG)composite hydrogels were developed for an in situ minimal invasive injection that enhance osteogenesis in the expanded palate.The component of 1 wt%MBG was adopted for enhanced mechanical strength,matched degradation rate and ion dissolution,excellent in vitro biocompatibility and osteoinductivity.Effects of 1%MBG/FG composite hydrogel on osteogenesis in expanded mid-palatal sutures with/without retention were evaluated in the standardized model.The results demonstrated that injection of 1%MBG/FG composite hydrogel significantly promoted bone formation within the expanded mid-palatal suture,inhibited osteoclastogenesis and benefited the balance of bone remodeling towards osteogenesis.Combination of retainer and injectable biomaterial was demonstrated as a promising treatment to reduce relapse rate and enhance osteogenesis after RME.The model establishment and the composite hydrogel development in this article might provide new insight to other craniomaxillofacial deformity treatment and design of bone-repairing biomaterials with higher regenerative efficiency. | Hanjiang Zhao Xiangyu Wang Anting Jin Minjiao Wang Zeying Wang Xingtai Huang Jiewen Dai Xudong Wang Dan Lin Steve GF.Shen | 2022 | Bioactive Materials2022，7，12： | 2 |
| 14 | Association between gene polymorphisms of vitamin D receptor and pulmonary tuberculosis susceptibility:a meta-analysis显示文摘Background:The vitamin D receptor(VDR) gene is a primary candidate gene for tuberculosis susceptibility,but results of previous studies are somewhat contradictory and underpowered.Thus,it is essential to further explore the association between VDR gene polymorphisms and risk of pulmonary tuberculosis(PTB).Methods:A systematic review and meta-analysis about the association between FokI,TaqI,ApaI and BsmI polymorphisms and PTB susceptibility was conducted.Statistical Package for Social Science(Version 13.0) and Review Manager(Version 4.2,The Cochrane Collaboration) were used to analyze the data reported in studies.Results:A total of 13 studies with 2 262 cases and 2 833 controls were involved in the FokI polymorphism,and the results showed FokI polymorphism was associated with PTB susceptibility(allele f vs F:OR=1.12,95% CI=[1.02,1.23];the additive effect model ff vs FF:OR=1.40,95%CI=[1.10,1.77];the recessive genetic model ff vs Ff+FF:OR=1.39,95%CI=[1.12,1.71]).No significant associations were observed between TaqI(15 studies with 3 031 cases and 3 132 controls),ApaI(7 studies with 1 495 cases and 1 922 controls),BsmI(6 studies with 919 cases and 1 250 controls) variants and PTB susceptibility.Conclusion:We found variant FokI polymorphism of VDR gene may play a risky role in PTB development,and the genetic model was presumed to be recessive. | Su Qian Ma Xiangyu Lin Hui Li Ying Hu Daiyu Xiong Hongyan Xu Rufu Li Yafei | 2011 | Journal of Medical Colleges of PLA(China)2011，26，2： | 2 |
| 15 | An Optimal Bit-Rate Allocation Algorithm to Improve Transmission Efficiency of Images in Deep Space Exploration显示文摘As fixed compression ratio is used in traditional deep space exploration image transmission application,the same compression code rate is allocated to each image.However,since the information of each image in a space observation mission is nonuniform,the image with more information will inevitably lead to more compression distortion than the image with less information.Obviously,it’s not an efficient way to transmit information in terms of data importance or overall distortion.Therefore,we proposed a combinatorial optimal bit rate allocation algorithm to improve the efficiency of image transmission in space application.Different from traditional method,the rate-distortion model of wavelet coefficients for each image in a transmission task was built,and under the overall maximum transmission rate constraint,an bit-rate optimal allocation was applied for each image to minimize the overall distortion of a batch of images.The proposed algorithm can be widely used in image compression algorithm with embedded code stream characteristics,such as JPEG2000 and SPIHT.Experimental results shows that in the range of 2.6 to 10 compression ratio,the algorithm can reduce image distortion MSB by 40%~64%at the same overall transmission code rate,which equivalent to improvement of PSNR 3 dB to 5.4 dB. | Yong Xu Jionghui Li Xiangyu Lin Fan Bai | 2020 | China Communications2020，17，7： | 2 |
| 16 | Recent advances in access to overcome cancer drug resistance by nanocarrier drug delivery system显示文摘Cancer is currently one of the most intractable diseases causing human death.Although the prognosis of tumor patients has been improved to a certain extent through various modern treatment methods,multidrug resistance(MDR)of tumor cells is still a major problem leading to clinical treatment failure.Chemotherapy resistance refers to the resistance of tumor cells and/or tissues to a drug,usually inherent or developed during treatment.Therefore,an urgent need to research the ideal drug delivery system to overcome the shortcoming of traditional chemotherapy.The rapid development of nanotechnology has brought us new enlightenments to solve this problem.The novel nanocarrier provides a considerably effective treatment to overcome the limitations of chemotherapy or other drugs resulting from systemic side effects such as resistance,high toxicity,lack of targeting,and off-target.Herein,we introduce several tumor MDR mechanisms and discuss novel nanoparticle technology applied to surmount cancer drug resistance.Nanomaterials contain liposomes,polymer conjugates,micelles,dendrimers,carbon-based,metal nanoparticles,and nucleotides which can be used to deliver chemotherapeutic drugs,photosensitizers,and small interfering RNA(siRNA).This review aims to elucidate the advantages of nanomedicine in overcoming cancer drug resistance and discuss the latest developments. | Xiangyu Sun Ping Zhao Jierou Lin Kun Chen Jianliang Shen | 2023 | Cancer Drug Resistance2023，6，2： | 1 |
| 17 | The multiple roles for Sox2 in stem cell maintenance and tumorigenesis显示文摘 | Kuancan Liu Baoshun Lin Meng Zhao Xiangyue Yang Min Chen Anding Gao Fei Liu Jianwen Que Xiaopeng Lan | 2013 | Cellular Signalling2013，，5： | 1 |
| 18 | Disease severity dictates SARS-CoV-2-specific neutralizing antibody responses in COVID-19显示文摘COVID-19 patients exhibit differential disease severity after SARS-CoV-2 infection.It is currently unknown as to the correlation between the magnitude of neutralizing antibody(NAb)responses and the disease severity in COVID-19 patients.In a cohort of 59 recovered patients with disease severity including severe,moderate,mild,and asymptomatic,we observed the positive correlation between serum neutralizing capacity and disease severity,in particular,the highest NAb capacity in sera from the patients with severe disease,while a lack of ability of asymptomatic patients to mount competent NAbs.Furthermore,the compositions of NAb subtypes were also different between recovered patients with severe symptoms and with mild-tomoderate symptoms.These results reveal the tremendous heterogeneity of SARS-CoV-2-specific NAb responses and their correlations to disease severity,highlighting the needs of future vaccination in COVID-19 patients recovered from asymptomatic or mild illness. | Xiangyu Chen Zhiwei Pan Shuai Yue Fei Yu Junsong Zhang Yang Yang Ren Li Bingfeng Liu Xiaofan Yang Leiqiong Gao Zhirong Li Yao Lin Qizhao Huang Lifan Xu Jianfang Tang Li Hu Jing Zhao Pinghuang Liu Guozhong Zhang Yaokai Chen Kai Deng Lilin Ye | 2020 | Signal Transduction and Targeted Therapy2020，5，1： | 1 |
| 19 | Effects of Al 2 O 3 addition on the microstructure and microwave dielectric properties of Ba 4 Nd 9.33 Ti 18 O 54 ceramics显示文摘 | Xiaogang Yao Huixing Lin Xiangyu Zhao Wei Chen Lan Luo | 2012 | Ceramics International2012，，： | 1 |
| 20 | Fast Mode Decision Algorithm for Spatial and Coarse Grain Quality Scalable Video Coding显示文摘 | Huang Aiai Lin Xiangyu Chen Yaowu | 2009 | Computer Network and Multimedia Technology2009，18，20： | 1 |
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