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| 1 | Recent advances on rare earths in solid lithium ion conductors显示文摘Solid lithium-ion-conducting material is the key component in the fabrication of next-gene ration all solid state lithium ion batteries(LIBs)which would exhibit superior safety and performance compared with the currently widely used ones that resort to essentially inflammable and volatile organic solvents.To date,great efforts have been made in developing solid conductors with high lithium ion conductivity,such as polymers and inorganic materials.Rare earths play a very important role in this area and have attracted extensive interest since the recent decades for their unique properties in the realm of solidstate inorganic lithium-ion-conducting electrolyte materials.In this introduction,we focus on the role of rare earths in solid conductors for lithium ion,especially in a few most studied systems such as perovskites,garnets,silicates,borohydride and the recently reported halides in which rare earths act as a key framing component.Besides,the effect of rare earths as dopants is also discussed in some recently studied systems.Valence,coordination,and size are the most important factors that influence the crystal structure and property of these lithium ion conductors.The aim of this review is to highlight the great potentials of these unique elements of rare earths,and to help improve the performance of existing materials and explore new applications in the development of new LIBs with high performances. | Qian Zhang Zhiqing Gao Xiaomeng Shi Chao Zhang Kang Liu Jun Zhang Liang Zhou Chunjie Ma Yaping Du | 2021 | Journal of Rare Earths2021,39,1: | 2 |
| 2 | Water-soluble dendritic-linear triblock copolymer-modified mag-netic nanoparticles: Preparation, characterization and drug release properties 显示文摘 | WU Xiaomeng HE Xiaohua ZHONG Liang | 2011 | J Mater Chem2011,21,13: | 1 |
| 3 | Expression levels and genetic polymorphisms of interleukin-2 and interleukin-10as biomarkers of Graves’ disease显示文摘 | Cuige Liang Wenhua Du Qingyu Dong Xiaomeng Liu Wenxia Li Yueli Wang Guanqi Gao | 2015 | Experimental and Therapeutic Medicine2015,,: | 1 |
| 4 | Local singularity and S–A methods for analyzing ore-producing anomalies in the Jianbiannongchang area of Heilongjiang,China显示文摘The Heilongjiang Jianbiannongchang area is located at the confluence of the Great and Lesser Xing’an Ranges.This area has a complex magmatic and tectonic evolutionary history that has resulted in a complex and diverse geological background for mineralization.In this study,isometric logarithmic ratio(ILR)transformations of Au,Cu,Pb,Zn,and Sb contents were performed in the1:50,000 soil geochemical data of the Jianbiannongchang area.Robust principal component analysis(RPCA)was conducted based on ILR transformation.The local singularity and spectrum-area(S-A)methods were used to extract information on mineralogic anomalies.The results showed that:(1)the transformed data eliminated the influence of the original data closure effect,and the PC1and PC2 information obtained by applying RPCA reflected ore-producing element anomalies dominated by Au and Cu.(2)The local singularity method can enhance the information of the local strong and weak slow anomalies.After performing local singularity analysis on PC1 and PC2,the obtained local anomalies reflected the local singularity spatial anomaly patterns related to Cu and Au mineralization in this area,which is an effective method for trapping ore-producing anomalies.(3)Furthermore,the composite anomaly decomposition of PC1 and PC2 was performed using the S-A method,and the screened anomalous and background fields reflect the ore-producing anomalies related to Cu and Au mineralization.This information is in agreement with known Cu and Au mineralization.(4)The geochemical anomalies with mineralization potential were obtained outside the known mineralization sites by integrating the information of oreproducing anomalies extracted by the local singularity and S-A methods,providing the theoretical basis and exploration direction for future exploration in the study area. | Zhonghai Zhao Kai Qiao Yiwen Liu Xiaomeng Cui Binbin Cheng Shanshan Liang Chenglu Li | 2023 | Acta Geochimica2023,42,2: | 1 |
| 5 | Historic and future trends of vehicle emissions in Beijing, 1998–2020: A policy assessment for the most stringent vehicle emission control program in China显示文摘 | Shaojun Zhang Ye Wu Xiaomeng Wu Mengliang Li Yunshan Ge Bin Liang Yueyun Xu Yu Zhou Huan Liu Lixin Fu Jiming Hao | 2013 | Atmospheric Environment2013,,: | 1 |
| 6 | The quasi-activity coefficients of non-electrolytes in aqueous solution with organic ions and its application on the phase splitting behaviors prediction for CO_(2) absorption显示文摘CO_(2)capture with a low energy consumption is of important application significance for reducing CO_(2)emission.The phase-change absorbent developed in recent years shows its potential for low-energy CO_(2)capture.The unclear phase-splitting rule hinders the efficient development of CO_(2)phase-change absorbents.To predict phase-splitting behaviors of mono/poly-amine-organic solvent-water system with various concentrations,a quasi-activity coefficient was developed based on Debye&Mc Aulay equation and some Density function theory descriptors.Six models based on Debye&Mc Aulay equation were developed with different ion radius,descriptors or poly-amine-CO_(2)products.The phase-splitting boundary was drawn on the model with the best predictability.This quasi-activity coefficient would provide guidance for the phase-splitting systems development,especially for polyamines. | Xiaomeng Zhao Xingyu Li Changjun Liu Shan Zhong Houfang Lu Hairong Yue Kui Ma Lei Song Siyang Tang Bin Liang | 2022 | Chinese Journal of Chemical Engineering2022,35,3: | 1 |
| 7 | 3-Thiomorpholin-8-oxo-8 H -acenaphtho [1,2- b ] pyrrole-9-carbonitrile ( S1 ) derivatives as pan-Bcl-2-inhibitors of Bcl-2, Bcl-x L and Mcl-1显示文摘 | Ting Song Xiangqian Li Xilong Chang Xiaomeng Liang Yan Zhao Guiye Wu Shenghui Xie Pengchen Su Zhiyong Wu Yingang Feng Zhichao Zhang | 2013 | Bioorganic & Medicinal Chemistry2013,,1: | 1 |
| 8 | Historic and future trends of vehicle emissions in Beijing, 1998–2020: A policy assessment for the most stringent vehicle emission control program in China显示文摘 | Shaojun Zhang Ye Wu Xiaomeng Wu Mengliang Li Yunshan Ge Bin Liang Yueyun Xu Yu Zhou Huan Liu Lixin Fu Jiming Hao | 2013 | Atmospheric Environment2013,,: | 1 |
| 9 | METTL3-mediated m^(6)A modification of HMGA2 mRNA promotes subretinal fibrosis and epithelial-mesenchymal transition显示文摘Subretinal fibrosis is a major cause of the poor visual prognosis for patients with neovascular age-related macular degeneration(nAMD).Myofibroblasts originated from retinal pigment epithelial(RPE)cells through epithelial-mesenchymal transition(EMT)contribute to the fibrosis formation.N^(6)-Methyladenosine(m^(6)A)modification has been implicated in the EMT process and multiple fibrotic diseases.The role of m^(6)A modification in EMT-related subretinal fibrosis has not yet been elucidated.In this study,we found that during subretinal fibrosis in the mouse model of laser-induced choroidal neovascularization,METTL3 was upregulated in RPE cells.Through m^(6)A epitranscriptomic microarray and further verification,high-mobility group AT-hook 2(HMGA2)was identified as thekey downstream target of METTL3,subsequently activating potent EMT-inducing transcription factor SNAIL.Finally,by subretinal injections of adeno-associated virus vectors,we confirmed that METTL3 deficiency in RPE cells could efficiently attenuate subretinal fibrosis in vivo.In conclusion,our present research identified an epigenetic mechanism of METTL3-m^(6)A-HMGA2 in subretinal fibrosis and EMT of RPE cells,providing a novel therapeutic target for subretinal fibrosis secondary to nAMD. | Yuwei Wang Yuhong Chen Jian Liang Mei Jiang Ting Zhang Xiaoling Wan Jiahui Wu Xiaomeng Li Jieqiong Chen Junran Sun Yifan Hu Peirong Huang Jingyang Feng Te Liu Xiaodong Sun | 2023 | Journal of Molecular Cell Biology2023,15,3: | 1 |
| 10 | Synergistic effects of carbon cycle metabolism and photosynthesis in Chinese cabbage under salt stress显示文摘Chinese cabbage(Brassica rapa ssp. pekinensis) has a long cultivation history and is one of the vegetable crops with the largest cultivation area in China. However, salt stress severely damages photosynthesis and hormone metabolism, nutritional balances, and results in ion toxicity in plants. To better understand the mechanisms of salt-induced growth inhibition in Chinese cabbage, RNA-seq and physiological index determination were conducted to explore the impacts of salt stress on carbon cycle metabolism and photosynthesis in Chinese cabbage. Here, we found that the number of thylakoids and grana lamellae and the content of starch granules and chlorophyll in the leaves of Chinese cabbage under salt stress showed a time-dependent response, first increasing and then decreasing. Chinese cabbage increased the transcript levels of genes related to the photosynthetic apparatus and carbon metabolism under salt stress, probably in an attempt to alleviate damage to the photosynthetic system and enhance CO_(2) fixation and energy metabolism. The transcription of genes related to starch and sucrose synthesis and degradation were also enhanced;this might have been an attempt to maintain intracellular osmotic pressure by increasing soluble sugar concentrations. Soluble sugars could also be used as potential reactive oxygen species(ROS) scavengers, in concert with peroxidase(POD)enzymes, to eliminate ROS that accumulate during metabolic processes. Our study characterizes the synergistic response network of carbon metabolism and photosynthesis under salt stress. | Hao Liang Qiling Shi Xing Li Peipei Gao Daling Feng Xiaomeng Zhang Yin Lu Jingsen Yan Shuxing Shen Jianjun Zhao Wei Ma | 2024 | Horticultural Plant Journal2024,10,2: | 0 |
| 11 | Targeting cytokinesis bridge proteins to kill high-CIN type tumors显示文摘As a common feature of tumors,chromosomal instability(CIN)not only forces carcinomatous evolution,but also loads cancer cells with extra pressure through a robust imbalance of genome patterning that may be used for cancer treatment.Errors in cytokinesis increase CIN,so cytokinesis components are valuable targets for treating cancer.However,due to the short time span and confined space of cytokinesis bridges,profiling cytokinesis fac-tors is challenging.Taking advantage of engineered ascorbate peroxidase(APEX2),we established a cytokinesis bridge-APEX reaction in living cells.A total of 218 cytokinesis bridge proteins were identified with high relia-bility.Knockdown of cytokinesis bridge genes generated micronuclei that activate the cGAS-pathway and cause apoptosis in cancer cells bearing high CIN rather than low CIN.Thus,our study proposes a strategy for killing high-CIN tumors regardless of tumor type,and provides a proteome resource of cytokinetic bridges for future research. | Bingteng Xie Xiaoling Liang Wei Yue Jihong Ma Xinyu Li Na Zhang Pan Wang Chang Liu Xiaomeng Shi Jie Qiao Peng Zou Mo Li | 2021 | Fundamental Research2021,1,6: | 0 |
| 12 | WSB1 regulates c-Myc expression through β-catenin signaling and forms a feedforward circuit显示文摘The dysregulation of transcription factors is widely associated with tumorigenesis.As the most well-defined transcription factor in multiple types of cancer,c-Myc can transform cells by transactivating various downstream genes.Given that there is no effective way to directly inhibit c-Myc,c-Myc targeting strategies hold great potential for cancer therapy.In this study,we found that WSB1,which has a highly positive correlation with c-Myc in 10 cancer cell lines and clinical samples,is a direct target gene of c-Myc,and can positively regulate c-Myc expression,which forms a feedforward circuit promoting cancer development.RNA sequencing results from Bel-7402 cells confirmed that WSB1 promoted cMyc expression through theβ-catenin pathway.Mechanistically,WSB1 affectedβ-catenin destruction complex-PPP2CA assembly and E3 ubiquitin ligase adaptorβ-TRCP recruitment,which inhibited the ubiquitination ofβ-catenin and transactivated c-Myc.Of interest,the effect of WSB1 on c-Myc was independent of its E3 ligase activity.Moreover,overexpressing WSB1 in the Bel-7402 xenograft model could further strengthen the tumor-driven effect of c-Myc overexpression.Thus,our findings revealed a novel mechanism involved in tumorigenesis in which the WSB1/c-Myc feedforward circuit played an essential role,highlighting a potential c-Myc intervention strategy in cancer treatment. | Xiaomeng Gao Jieqiong You Yanling Gong Meng Yuan Haiying Zhu Liang Fang Hong Zhu Meidan Ying Qiaojun He Bo Yang Ji Cao | 2022 | Acta Pharmaceutica Sinica B2022,12,3: | 0 |
| 13 | Understanding University President Leadership Research in China:A Review显示文摘This article explores the Chinese literature on Chinese higher educational leadership in order to contribute to the international literature generally and facilitate Chinese higher education leadership research in particular.The seven themes identified in this literature are:the president accountability system led by the Communist Party of China(CPC)party committee;leadership team construction in universities and colleges;the common characteristics of university presidents in China;the accomplishments of university presidents;the relationship between university development and presidents’accomplishments the selection mechanism for university presidents;and the professionalization of governance and the professionalism of university presidents.Future research directions are also discussed in order to contribute the research in this area. | Peng LIU WANG Xiaoyang LIANG Xiaomeng | 2019 | Frontiers of Education in China2019,14,1: | 0 |
| 14 | Visualizing the nucleoplasmic maturation of human pre-60S ribosomal particles显示文摘Eukaryotic ribosome assembly is a highly orchestrated process that involves over two hundred protein factors.After early assembly events on nascent rRNA in the nucleolus,pre-60S particles undergo continuous maturation steps in the nucleoplasm,and prepare for nuclear export.Here,we report eleven cryo-EM structures of the nuclear pre-60S particles isolated from human cells through epitope-tagged GNL2,at resolutions of 2.8–4.3Å.These high-resolution snapshots provide fine details for several major structural remodeling events at a virtual temporal resolution.Two new human nuclear factors,L10K and C11orf98,were also identified.Comparative structural analyses reveal that many assembly factors act as successive place holders to control the timing of factor association/dissociation events.They display multi-phasic binding properties for different domains and generate complex binding inter-dependencies as a means to guide the rRNA maturation process towards its mature conformation.Overall,our data reveal that nuclear assembly of human pre-60S particles is generally hierarchical with short branch pathways,and a few factors display specific roles as rRNA chaperones by confining rRNA helices locally to facilitate their folding,such as the C-terminal domain of SDAD1. | Yunyang Zhang Xiaomeng Liang Sha Luo Yan Chen Yu Li Chengying Ma Ningning Li Ning Gao | 2023 | Cell Research2023,33,11: | 0 |
| 15 | Transmission Network Expansion Planning Considering the Generators’Contribution to Uncertainty Accommodation显示文摘This paper presents an optimization for transmission network expansion planning(TNEP)under uncertainty circumstances.This TNEP model introduces the approach of parameter sets to describe the range that all possible realizations of uncertainties in load and renewable generation can reach.While optimizing the TNEP solution,the output of each generator is modeled as an uncertain variable to linearly respond to changes caused by uncertainties,which is constrained by the extent to which uncertain parameters may change the operational range of generators,and network topology.This paper demonstrates that the robust optimization approach is effective to make the problem with uncertainties tractable by converting it into a deterministic optimization,and with the genetic algorithm,the optimal TNEP solution is derived iteratively.Compared with other robust TNEP results tested on IEEE 24-bus systems,the proposed method produces a least-cost expansion plan without losing robustness.In addition,the contribution that each generator can make to accommodate with every uncertainty is optimally quantified.Effects imposed by different uncertainty levels are analyzed to provide a compromise of the conservativeness of TNEP solutions. | Xingning Han Liang Zhao Jinyu Wen Xiaomeng Ai Ju Liu Dongjun Yang | 2017 | CSEE Journal of Power and Energy Systems2017,3,4: | 0 |
| 16 | De Novo Transcriptome Analysis in Hevea brasiliensis to Unveil Genes Involved in Low Temperature Stress Response显示文摘Low temperature is one of the adversities threatening the growth and development and reduces the yield of rubber trees.However,molecular mechanisms toward rubber trees in response to low temperature are largely unclear.In this study,7,159 and 7,600 differentially expressed genes(DEGs)were identified in‘Reyan 73397’rubber trees.Through GO analysis,the catalytic activity was the representative of the GO term in the only DEGs at the two studied temperatures(room temperature and 4°C,respectively),while KEGG analysis showed that carbon metabolism was the most important grouping under the comparison of these two temperatures.In addition,expression of 9 members of transcription factor MYB family genes were further verified by qRT-PCR,and MYB family genes may play important roles in the regulation of rubber trees under low temperature stress.This study provided a theoretical foundation for(1)revealing the molecular mechanisms of rubber trees in response to low temperature and(2)breeding of tolerant varieties of rubber trees. | Bingsong Yang Xiaomeng Shi Tingting Guo Meixia Liang | 2023 | Phyton-International Journal of Experimental Botany2023,92,2: | 0 |
| 17 | Spatially Isolated Noble-Metal-Free Redox Cocatalysts on CdS Nanorods for Increased Photocatalytic Hydrogen Generation显示文摘Spatially isolated oxidation and reduction cocatalysts on a semiconductor can realize efficient charge separation and thereby lead to increased photocatalytic hydrogen generation. However, the effective preparation of such photocatalysts has proven challenging.Herein, we report the facile synthesis of a novel noblemetal-free CdS/MoS/CoPi ternary photocatalyst via a visible light-induced synthesis route, in which MoSreduction cocatalysts were precisely grown on the two terminals of CdS nanorods, while CoPi oxidation cocatalysts were preferentially anchored onto the sidewalls of CdS nanorods. Such spatially isolated MoSand CoPi redox cocatalysts endow CdS nanorods with a rapid charge separation, which enhances their hydrogen generation activity. The CdS/MoS/CoPi photocatalyst with optimized CoPi amount achieves the highest Hgeneration rate of 206 μmol/h, which is 21 and 2 times higher than that achieved by using CdS alone(9.7 μmol/h) and CdS/MoS(105 μmol/h), respectively. The present work highlights the effectiveness of the spatial isolation of reduction and oxidation sites for efficient charge separation and thereby provides a promising strategy for the preparation of highly active photocatalysts. | Xiaomeng Zhang Gege Zhao Zhongfei Li Liang Zhu Yingpeng Cheng Haiwei Du Chuhong Zhu Ya Dang Daochuan Jiang Yupeng Yuan | 2022 | Chinese Journal of Structural Chemistry2022,41,9: | 0 |
| 18 | Disentangling land model uncertainty via Matrix-based Ensemble Model Inter-comparison Platform(MEMIP)显示文摘Background:Large uncertainty in modeling land carbon(C)uptake heavily impedes the accurate prediction of the global C budget.Identifying the uncertainty sources among models is crucial for model improvement yet has been difficult due to multiple feedbacks within Earth System Models(ESMs).Here we present a Matrix-based Ensemble Model Inter-comparison Platform(MEMIP)under a unified model traceability framework to evaluate multiple soil organic carbon(SOC)models.Using the MEMIP,we analyzed how the vertically resolved soil biogeochemistry structure influences SOC prediction in two soil organic matter(SOM)models.By comparing the model outputs from the C-only and CN modes,the SOC differences contributed by individual processes and N feedback between vegetation and soil were explicitly disentangled.Results:Results showed that the multi-layer models with a vertically resolved structure predicted significantly higher SOC than the single layer models over the historical simulation(1900–2000).The SOC difference between the multi-layer models was remarkably higher than between the single-layer models.Traceability analysis indicated that over 80%of the SOC increase in the multi-layer models was contributed by the incorporation of depth-related processes,while SOC differences were similarly contributed by the processes and N feedback between models with the same soil depth representation.Conclusions:The output suggested that feedback is a non-negligible contributor to the inter-model difference of SOC prediction,especially between models with similar process representation.Further analysis with TRENDY v7 and more extensive MEMIP outputs illustrated the potential important role of multi-layer structure to enlarge the current ensemble spread and the necessity of more detail model decomposition to fully disentangle inter-model differences.We stressed the importance of analyzing ensemble outputs from the fundamental model structures,and holding a holistic view in understanding the ensemble uncertainty. | Cuijuan Liao Yizhao Chen Jingmeng Wang Yishuang Liang Yansong Huang Zhongyi Lin Xingjie Lu Yuanyuan Huang Feng Tao Danica Lombardozzi Almut Arneth Daniel SGoll Atul Jain Stephen Sitch Yanluan Lin Wei Xue Xiaomeng Huang Yiqi Luo | 2022 | Ecological Processes2022,11,1: | 0 |
| 19 | Propylamine hydrobromide passivated tin-based perovskites to efficient solar cells显示文摘The development of tin-based devices with low toxicity is critical for the commercial viability of perovskite solar cells.However because tin halide is a stronger Lewis acid,its crystallization rate is extremely fast,resulting in the formation of numerous defects that affect the device performance of tin-based perovskite solar cells.Herein,propylamine hydrobromide(PABr)was added to the perovskite precursor solution as an additive to passivate defects and fabricate more uniform and dense perovskite films.Because propylamine cations are too large to enter the perovskite lattices,they only exist at the grain boundary to passivate surface defects and promote crystal growth in a preferred orientation.The PABr additive raises the average short-circuit current density from 19.45 to 25.47 mA·cm^(-2)by reducing carrier recombination induced by defects.Furthermore,the device’s long-term illumination stability is improved after optimization,and the hysteresis effect is negligible.The addition of PABr results in a power conversion efficiency of 9.35%. | Xiaomeng Li Pengcheng Jia Fanwen Meng Xingyu Zhang Yang Tang Bo Song Chang Gao Liang Qin Feng Teng Yanbing Hou | 2023 | International Journal of Minerals,Metallurgy and Materials2023,30,10: | 0 |
| 20 | The CropGPT project:Call for a global,coordinated effort in precision design breeding driven by Al using biological big data显示文摘Since the beginning of humanity,people have been seeking practical solutions to meet their most basic need:food.The advent of agriculture greatly increased the food supply and led to a rapid increase in the human population.Enhanced food production via agriculture can be attributed to both improved crop management practices and crop breeding through genetics.Plant(crop)breeding has been categorized into four major stages based on the techniques employed(Wallace et al.,2018). | Wanchao Zhu Rui Han Xiaoyang Shang Tao Zhou Chengyong Liang Xiaomeng Qin Hong Chen Zaiwen Feng Hongwei Zhang Xingming Fan Weifu Li Lin Li | 2024 | Molecular Plant2024,17,2: | 0 |