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| 1 | The ultraviolet photoconductive detector based on Al-doped ZnO thin film with fast response显示文摘We report fabrication and characterization of metal-semiconductor-metal photoconductive detectors based on Al-doped ZnO thin films fabricated by radio frequency magnetron sputtering.Optical and structural properties of the thin films were characterized using various techniques.At 6 V bias,a responsivity higher than 4 A/W in the wavelength shorter than 350 nm was obtained,and this responsibility dropped quickly and reached the noise floor in the visible region.Transient response measurement revealed that the detector had a fast photoresponse with a rise time of 9 ns and a fall time of 1.2 μs. | SUN Jian DAI Qian LIU FengJuan HUANG HaiQin LI ZhenJun ZHANG XiQing WANG YongSheng | 2011 | Science China(Physics,Mechanics & Astronomy)2011，54，1： | 4 |
| 2 | Organic photodetectors based on transparent electrodes for application in ultraviolet light detection显示文摘A high performance heterojunction organic ultraviolet photodetector based on NPB and Bphen has been fabricated.A transparent conducting polymer PEDOT:PSS coated quartz substrate instead of ITO coated glass substrate as anode is propitious to detect shorter wavelength ultraviolet light.As a result,the device shows a low dark current density,a high responsivity of 502 mA/W and a detectivity of 2.67×10 12 cm Hz 1/2 /W which is illuminated by a 220 nm ultraviolet light with an intensity of 1.6 mW/cm 2.Moreover,the performance of the PEDOT:PSS transparent electrode device is better than the semi-transparent Al electrode device electrode because of the higher transmittance and electrode properties. | DAI Qian ZHU Lu SUN Jian ZHANG XiQing WANG YongSheng | 2012 | Science China(Technological Sciences)2012，55，6： | 4 |
| 3 | A viral vector expressing hypoxia-inducible factor 1 alpha inhibits hippocampal neuronal apoptosis显示文摘Hypoxia-inducible factor 1(HIF-1) attenuates amyloid-beta protein neurotoxicity and decreases apoptosis induced by oxidative stress or hypoxia in cortical neurons. In this study, we constructed a recombinant adeno-associated virus(rAAV) vector expressing the human HIF-1α gene(rAAV-HIF-1α), and tested the assumption that rAAV-HIF-1α represses hippocampal neuronal apoptosis induced by amyloid-beta protein. Our results confirmed that rAAV-HIF-1α significantly reduces apoptosis induced by amyloid-beta protein in primary cultured hippocampal neurons. Direct intracerebral rAAV-HIF-1α administration also induced robust and prolonged HIF-1α production in rat hippocampus. Single rAAV-HIF-1α administration resulted in decreased apoptosis of hippocampal neurons in an Alzheimer's disease rat model established by intracerebroventricular injection of aggregated amyloid-beta protein(25–35). Our in vitro and in vivo findings demonstrate that HIF-1 has potential for attenuating hippocampal neuronal apoptosis induced by amyloid-beta protein, and provides experimental support for treatment of neurodegenerative diseases using gene therapy. | Xiqing Chai Weina Kong Lingyun Liu Wenguo Yu Zhenqing Zhang Yimin Sun | 2014 | Neural Regeneration Research2014，9，11： | 4 |
| 4 | Technology for recycling and regenerating graphite from spent lithium-ion batteries显示文摘With the annual increase in the amount of lithium-ion batteries(LIBs),the development of spent LIBs recycling technology has gradually attracted attention.Graphite is one of the most critical materials for LIBs,which is listed as a key energy source by many developed countries.However,it was neglected in spent LIBs recycling,leading to pollution of the environment and waste of resources.In this paper,the latest research progress for recycling of graphite from spent LIBs was summarized.Especially,the processes of pretreatment,graphite enrichment and purification,and materials regeneration for graphite recovery are introduced in details.Finally,the problems and opportunities of graphite recycling are raised. | Chenxing Yi Lijie Zhou Xiqing Wu Wei Sun Longsheng Yi Yue Yang | 2021 | Chinese Journal of Chemical Engineering2021，34，11： | 2 |
| 5 | Effect of+ Gz exposure on memory and behavior in rats 显示文摘 | WEI Yingbo SUN Xiqing CAO Xinsheng | 2003 | Chin JAerospace Med2003，14，1： | 1 |
| 6 | Accelera-tion after-effects on learning and memory in rats: + 10 Gz or+ 6 Gz for 3 min 显示文摘 | CAO Xinsheng SUN Xiqing ZHANG Shu | 2007 | Neuroscience Letters2007，413，： | 1 |
| 7 | The influenceof repeated + Gz exposures on HSP70 expression in rat brain显示文摘 | LI Jinsheng SUN Xiqing WU Xingyu | 2002 | Chin J Aerospace Med2002，13，3： | 1 |
| 8 | The potential effects and mechanism of repeated high +Gz exposures on the brain显示文摘 | SUN Xiqing | 1998 | Space Medicine & Medical Engineering1998，11，1： | 1 |
| 9 | The repeated homogeneous balance method and its applications to nonlin- ear partial differential equations显示文摘 | ZHAO Xiqing WANG Limin SUN Weijun | 2006 | Chaos Solitons and Fractals2006，28，： | 1 |
| 10 | A novel ultrafine leady oxide prepared from spent lead pastes for application as cathode of lead acid battery显示文摘 | Danni Yang Jianwen Liu Qin Wang Xiqing Yuan Xinfeng Zhu Lei Li Wei Zhang Yucheng Hu Xiaojuan Sun R. Vasant Kumar Jiakuan Yang | 2014 | Journal of Power Sources2014，，： | 1 |
| 11 | HuR-mediated nucleocytoplasmic translocation of HOTAIR relieves its inhibition of osteogenic differentiation and promotes bone formation显示文摘Bone marrow mesenchymal stem cell(BMSC)osteogenic differentiation and osteoblast function play critical roles in bone formation,which is a highly regulated process.Long noncoding RNAs(lncRNAs)perform diverse functions in a variety of biological processes,including BMSC osteogenic differentiation.Although several studies have reported that HOX transcript antisense RNA(HOTAIR)is involved in BMSC osteogenic differentiation,its effect on bone formation in vivo remains unclear.Here,by constructing transgenic mice with BMSC(Prx1-HOTAIR)-and osteoblast(Bglap-HOTAIR)-specific overexpression of HOTAIR,we found that Prx1-HOTAIR and Bglap-HOTAIR transgenic mice show different bone phenotypes in vivo.Specifically,Prx1-HOTAIR mice showed delayed bone formation,while Bglap-HOTAIR mice showed increased bone formation.HOTAIR inhibits BMSC osteogenic differentiation but promotes osteoblast function in vitro.Furthermore,we identified that HOTAIR is mainly located in the nucleus of BMSCs and in the cytoplasm of osteoblasts.HOTAIR displays a nucleocytoplasmic translocation pattern during BMSC osteogenic differentiation.We first identified that the RNA-binding protein human antigen R(HuR)is responsible for HOTAIR nucleocytoplasmic translocation.HOTAIR is essential for osteoblast function,and cytoplasmic HOTAIR binds to miR-214 and acts as a ceRNA to increase Atf4 protein levels and osteoblast function.BglapHOTAIR mice,but not Prx1-HOTAIR mice,showed alleviation of bone loss induced by unloading.This study reveals the importance of temporal and spatial regulation of HOTAIR in BMSC osteogenic differentiation and bone formation,which provides new insights into precise regulation as a target for bone loss. | Yuheng Li Weijia Sun Jianwei Li Ruikai Du Wenjuan Xing Xinxin Yuan Guohui Zhong Dingsheng Zhao Zizhong Liu Xiaoyan Jin Junjie Pan Youyou Li Qi Li Guanghan Kan Xuan Han Shukuan Ling Xiqing Sun Yingxian Li | 2023 | Bone Research2023，11，4： | 0 |
| 12 | Software defined intelligent satellite-terrestrial integrated networks:Insights and challenges显示文摘Satellite-Terrestrial integrated Networks(STNs)have been advocated by both academia and industry as a promising network paradigm to achieve service continuity and ubiquity.However,STNs suffer from problems including poor flexibility of network architecture,low adaptability to dynamic environments,the lack of network intelligence,and low resource utilization.To handle these challenges,a Software defined Intelligent STN(SISTN)architecture is introduced.Specifically,the hierarchical architecture of the proposal is described and a distributed deployment scheme for SISTNs controllers is proposed to realize agile and effective network management and control.Moreover,three use cases in SISTNs are discussed.Meanwhile,key techniques and their corresponding solutions are presented,followed by the identification of several open issues in SISTNs including compatibility with existing networks,the tradeoff between network flexibility and performance,and so on. | Shuo Yuan Mugen Peng Yaohua Sun Xiqing Liu | 2023 | Digital Communications and Networks2023，9，6： | 0 |
| 13 | Biological Characterization and Whole Genome Sequencing of a Genotype VII Newcastle Disease Virus Strain显示文摘[Objective] The aim of this paper was to study the genotype, pathogenicity and nucleotide difference between Newcastle disease virus(NDV) isolates and traditional NDV vaccine strain(La Sota). [Method] A suspected NDV strain was isolated from a chicken farm. The isolate was preliminarily determined by HA and HI tests. A pair of primers was designed based on the partial sequence of NDV F gene published in GenBank(accession No. JF950510.1). F gene was amplified by RT-PCR, cloned and sequenced. The sequencing result was compared with the F gene sequences published in GenBank, and the phylogenetic tree was constructed to analyze the genotypes. The pathogenicity of the virus was determined by mean death time(MDT) of chicken embryos, intracerebral pathogenicity index(ICPI) of one-day-old chicks and intravenous pathogenicity index(IVPI) of six-week-old chickens, respectively. Based on the NDV genome sequence published in GenBank(accession No. JF950510.1), nine pairs of primers were designed to amplify the genome sequence of the isolate, and its structure was analyzed. [Result] The length of F gene was about 500 bp, and a NDV strain of genotype VII was isolated. The MDT, ICPI and IVPI were 52.8 h, 1.675 and 2.46, respectively, indicating the isolate was a virulent strain. The whole genome sequence analysis results showed that the full genome length of the isolate was 15 192 bp, which had 6 more nu-cleotides than that of La Sota strain, and the homology between the two strains was 82.8%. [Conclusion] A virulent NDV strain of genotype Ⅶ was isolated, with low homology to La Sota strain in nucleotide sequence. | Sun Hualu Li Xiqing Bi Yunying Yu Zekun Li Sifei Liu Yang Li Mingyi Cui Xianlan | 2018 | Animal Husbandry and Feed Science2018，10，5： | 0 |
| 14 | Monitoring of CO2 Tension during High Frequency Jet Ventilation显示文摘 | Xiqing Sun Xingyu Wu | 2006 | Journal of US-China Medical Science2006，3，2： | 0 |
| 15 | Gas diffusion in catalyst layer of flow cell for CO_(2) electroreduction toward C_(2+) products显示文摘The use of gas diffusion electrode(GDE)based flow cell can realize industrial-scale CO_(2) reduction reactions(CO_(2)RRs).Controlling local CO_(2) and CO intermediate diffusion plays a key role in CO_(2)RR toward multi-carbon(C_(2+))products.In this work,local CO_(2) and CO intermediate diffusion through the catalyst layer(CL)was investigated for improving CO_(2)RR toward C_(2+)products.The gas permeability tests and finite element simulation results indicated CL can balance the CO_(2) gas diffusion and residence time of the CO intermediate,leading to a sufficient CO concentration with a suitable CO_(2)/H_(2)O supply for high C_(2+)products.As a result,an excellent selectivity of C_(2+)products~79%at a high current density of 400 mA·cm^(-2) could be obtained on the optimal 500 nm Cu CL(Cu500).This work provides a new insight into the optimization of CO_(2)/H_(2)O supply and local CO concentration by controlling CL for C_(2+)products in CO_(2)RR flow cell. | Xiqing Wang Qin Chen Yajiao Zhou Yao Tan Ye Wang Hongmei Li Yu Chen Mahmoud Sayed Ramadan A.Geioushy Nageh K.Allam Junwei Fu Yifei Sun Min Liu | 2024 | Nano Research2024，17，3： | 0 |
| 16 | Experimental study for frequency spectrum of turbulent boundary layer pressure fluctuation显示文摘An experimental study on TBL (turbulent boundary layer) pressure fluctuation frequeny spectrum of a revolution body is presented. With the measured results, a relation of convective frequency fo of the models is obtained. Relations of turbuleat wall-pressure fluctuation spectrum in transition region and development region to frequency and speed are obtained | PENG Linhui LU Jianhui (Ocean University of Qingdao Qingdao 266003) ZHU Xiqing SUN Yudong (CSSRC Wuxi 214082) | 1999 | Chinese Journal of Acoustics1999，18，3： | 0 |
| 17 | A prospective cohort study of the presence of SARS-CoV-2 in clinical samples from multiple bodily sites:implications for transmission routes of COVID-19显示文摘Objective: The coronavirus disease 2019 (COVID-19) epidemic resulting from severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has still spread globally. The occurrence of the Delta variant, which is more infectious and spreads faster than earlier forms of the virus that causes COVID-19, makes infection prevention more challenging. Therefore, this study aimed to gain a comprehensive insight into the transmission routes of SARS-CoV-2 for curbing the propagation of SARS-CoV-2 in human populations.Methods: We studied a prospective cohort of 576 patients admitted consecutively to the First Affiliated Hospital of Guangzhou Medical University from January 21 to June 8, 2020. These patients were chosen based on their similar clinical phenotypes or imaging findings. There were 21 (3.6%) laboratory-confirmed COVID-19 patients (16 severe and 5 mild cases) and 555 non-COVID-19 patients. The antibody response and routes and duration of viral shedding were systematically evaluated in serial clinical specimens. Moreover, SARS-CoV-2 RNA was also detected in a mouth rinse, urine, and tear samples. This study was approved by the Medical Ethical Committee of The First Affiliated Hospital of Guangzhou Medical University (approval No. 2020-77).Results: SARS-CoV-2 mainly existed in sputum, nasal and throat swabs, and feces samples. Virus latency was longer in sputum and feces samples than in nasopharyngeal samples. IgG antibody response in respiratory samples was related to disease severity. Although droplets and aerosols are the major transmission routes for COVID-19, covert routes of transmission from asymptomatic patients, contaminated surfaces, and wastewater are also of interest.Conclusion: Our findings provide a solid foundation for developing prophylactic measures against SARS-CoV-2. | Meixian Liu Huimin Huang Xiqing Bian Zhiyuan Zheng Na Li Baoqing Sun Jian-Lin Wu | 2022 | Journal of Bio-X Research2022，5，1： | 0 |
| 18 | Near-infrared light(NIR)-responsive nanoliposomes combining photodynamic therapy and chemotherapy for breast tumor control显示文摘Light-responsive carriers have been used for the controlled release of antitumor drugs in recent years.However, most light-responsive vectors require high-energy ultraviolet or visible light to achieve local drug release, and ultraviolet light would cause cellular damage. Near-infrared light has a deeper tissuepenetration depths and minimal harm to tissues, but it is difficult to cleave the chemical bond directly.The aim of this study is to develop a novel near-infrared light-responsive carrier for local release of antitumor drugs. Unsaturated phospholipids can be oxidized by singlet oxygen to achieve liposomal drug release, and singlet oxygen can be produced by photosensitizer under light irradiation. A new near-infrared light-responsive nanoliposome was designed that imparts light-triggered local drug release. Nanoliposomes, which were composed of matrix phospholipids and unsaturated phospholipids, were prepared by ammonium sulfate gradient method, and loaded with antitumor drug doxorubicin(DOX) and photosensitizer 1,4,8,11,15,18,22,25-octabutoxypalladium phthalocyanine. Under near-infrared light, photosensitizers could produce singlet oxygen and damage tumor cells by photodynamic therapy. Simultaneously, the unsaturated phospholipids were oxidized by singlet oxygen and result in DOX release, causing sustained cell damage by chemotherapy. Near-infrared light-responsive nanoliposomes exhibit enhanced anticancer activity owing to combined treatment of photodynamic therapy and chemotherapy. A new platform is thus offered for designing effective intracellular drug-release systems, holding great promise for future cancer therapy. | Guangzhao Lu Xiqing Gao He Zhang Yeye Zhang Yuan Yu Zhiguo Sun Wei Li Wei Wu Ying Lu Hao Zou | 2022 | Chinese Chemical Letters2022，33，4： | 0 |
| 19 | Tailoring carbon chains for repairing graphite from spent lithium-ion battery toward closed-circuit recycling显示文摘Graphite, as a strategic mineral resource, the recycling from spent lithium-ion batteries(LIBs) has attracted considerable attention for meeting considerable economic value. However, closed-circuit recycling still suffers from the lack of effective repair methods. Considering the existing defects, a series of Cchain length carbons have been successfully introduced to repair spent graphite. Obviously, with the evolution of carbon resources, the thickness and pores of the coating layer were tailored with the functional groups. Benefitting from the increased active sites and created fold structure, their coulombic efficiency is obviously restored from 14% to 86.89%, while the stable capacity is kept at approximately 384.9 mAh gafter 100 cycles. Moreover, their excellent rate properties are kept about approximately 200 mAh gat2 C, meeting the standard of commercial materials. Supported by the detailed kinetic behaviors, the enhanced rate is mainly dominated by pseudocapacitive behaviors, accompanied by deepening redox reactions. Meanwhile, the cost of the proposed approach for recycling spent graphite is 894.87 $ t^(-1),and the recycling profit for regenerating graphite is approximately 7000 $ t^(-1). Given this, this work is anticipated to shed light on the closed-circuit recycling of spent graphite and offer significant strategies to repair graphite. | Chenxing Yi Peng Ge Xiqing Wu Wei Sun Yue Yang | 2022 | Journal of Energy Chemistry2022，31，9： | 0 |
| 20 | Influencing factors of hospitalization costs for glaucoma patients under clinical pathway management显示文摘Background:To investigate and analyze the hospitalization costs of inpatients with primary acute angle closure glaucoma(PACG),and to explores the influencing factors of hospitalization cost and to provide reference for specialized hospitals to carry out clinical pathways.Methods:The first page diagnostic data of PACG patients’medical records were collected,and an Excel database was established according to the International Classification of Diseases(ICD-10)code.Statistical analysis of hospitalization data was performed using SPSS 17.0 software.Results:Hospitalization days and clinical pathway which affect the change of the hospitalization cost(P<0.001).Conclusions:Hospitalization day is an important factor affecting the hospitalization cost,reducing unnecessary hospitalization time can control the increase of hospitalization cost. | Bomin Lin Yangchu Li Wei Zhang Xiqing Liao Huiming Xiao Jianming Sun Yanwei Lin Aihua Lin | 2019 | Annals of Eye Science2019，，1： | 0 |
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