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| 1 | Growth ages of ferromanganese crusts from the western and central Pacific:Comparison between nannofossil analysis and ^(10)Be dating显示文摘Based on results of nannofossil analysis and 10Be dating in ferromanganese crusts M1-1 and A1-1 (no nannofossils were found in it),from the western and central Pacific respectively,it is found that the crust growth ages from nannofossil biostrati-graphy agree well with those based on 10Be isotope analysis. Both crusts have three growth layers,and the oldest layer was deposited in Miocene at about 12.80 Ma. The maximum,minimum,and average growth rates of crust A1-1 (from the central Pacific) are 8.11,1.92 and 3.47 mm/Ma,and those of crust M1-1 (from the western Pacific) are 2.93,0.47,and 0.94 mm/Ma. | CHENG Zhenbo SHI Xuefa WU Yonghua SU Xin LI Xiaoyan WANG Kunshan YANG Yongliang GE Shulan JU Xiaohua SHI Fengdeng M. Hiroyuki | 2006 | Chinese Science Bulletin2006，51，24： | 7 |
| 2 | Orofacial inflammatory pain affects the expression of MT1 and NADPH-d in rat caudal spinal trigeminal nucleus and trigeminal ganglion显示文摘Very little is known about the role of melatonin in the trigeminal system,including the function of melatonin receptor 1.In the present study,adult rats were injected with formaldehyde into the right vibrissae pad to establish a model of orofacial inflammatory pain.The distribution of melatonin receptor 1 and nicotinamide adenine dinucleotide phosphate diaphorase in the caudal spinal trigeminal nucleus and trigeminal ganglion was determined with immunohistochemistry and histochemistry.The results show that there are significant differences in melatonin receptor 1 expression and nicotinamide adenine dinucleotide phosphate diaphorase expression in the trigeminal ganglia and caudal spinal nucleus during the early stage of orofacial inflammatory pain.Our findings suggest that when melatonin receptor 1 expression in the caudal spinal nucleus is significantly reduced,melatonin's regulatory effect on pain is attenuated. | Fang Huang Hongwen He Wenguo Fan Yongliang Liu Hongyu Zhou Bin Cheng | 2013 | Neural Regeneration Research2013，8，32： | 4 |
| 3 | odeling of oil spill beaching along the coast of the Bohai Sea, China显示文摘 | Qing XU Yongcun CHENG Bingqing LIU Yongliang WEI | 2015 | Frontiers of Earth Science2015，9，4： | 2 |
| 4 | Effect of the organic additions on crystal growth behavior of ZrO 2 nanocrystals prepared via sol–gel process显示文摘 | Wenzhi Huang Jili Yang Xiangsheng Meng Yongliang Cheng Chunjie Wang Binglin Zou Zuhair Khan Zhen Wang Xueqiang Cao | 2011 | Chemical Engineering Journal2011，，3： | 2 |
| 5 | A yearlong study of water-soluble organic carbon in Beijing II: Light absorption properties显示文摘 | Zhenyu Du Kebin He Yuan Cheng Fengkui Duan Yongliang Ma Jiumeng Liu Xiaolu Zhang Mei Zheng Rodney Weber | 2014 | Atmospheric Environment2014，，： | 1 |
| 6 | A yearlong study of water-soluble organic carbon in Beijing II: Light absorption properties显示文摘 | Zhenyu Du Kebin He Yuan Cheng Fengkui Duan Yongliang Ma Jiumeng Liu Xiaolu Zhang Mei Zheng Rodney Weber | 2014 | Atmospheric Environment2014，，： | 1 |
| 7 | Fabrication of CoFe2 O4 hollow fibers by direct annealing of the electrospun composite fibers and their magnetic properties 显示文摘 | CHENG Yongliang ZOU Binglin YANG Jill | 2011 | Crysteng- comm2011，13，7： | 1 |
| 8 | TGFBI expression reduces in vitro and in vivo metastatic potential of lung and breast tumor cells显示文摘 | Gengyun Wen Michael A. Partridge Bingyan Li Mei Hong Wupeng Liao Simon K. Cheng Yongliang Zhao Gloria M. Calaf Tian Liu Jun Zhou Zengli Zhang Tom K. Hei | 2011 | Cancer Letters2011，，1： | 1 |
| 9 | Dynamic Characteristics Analysis with Multi-Directional Coupling in a TBM Mainframe显示文摘The cutterhead of a full-face rock tunnel boring machine(TBM)is constantly subjected to varying impact and dynamic loads during tunneling processes,resulting in relatively large vibrations that could easily lead to fatigue cracking of the entire machine and a ect the tunneling performance and efficiency.To explore the dynamic characteristics of the TBM mainframe,a TBM from a water-diversion project is investigated in this research.According to the TBM vibration transmission route,an equivalent dynamic model of the TBM mainframe is established using the lumped-mass method in which the relevant dynamic parameters are solved.Additionally,the dynamic response characteristics of the TBM mainframe are analyzed.The results indicate that the vibration levels in three directions are approximately the same,the multi-directional vibration of the cutterhead is more intense than that of other components,and the vibration and external excitation exhibit identical change trends.A set of vibration field tests is performed to analyze the in situ dynamic responses of the mainframe and verify the correctness of the dynamic model.The theoretical and measured acceleration values of the TBM mainframe have the same magnitude,which proves the validity of the dynamic model and its solution.The aforementioned results provide an important theoretical value and practical significance for the design and assessment of the TBM mainframe. | Laikuang Lin Yimin Xia Zhengguang Li Caizhang Wu Yongliang Cheng Qing Tan | 2019 | Chinese Journal of Mechanical Engineering2019，32，6： | 1 |
| 10 | Tubulointerstitial nephritis antigen-like 1 is a novel matricellular protein that promotes gastric bacterial colonization and gastritis in the setting of Helicobacter pylori infection显示文摘The interaction between the gastric epithelium and immune cells plays key roles in H. pylori-associated pathology. Here, we demonstrate a procolonization and proinflammatory role of tubulointerstitial nephritis antigen-like 1 (TINAGL1), a newly discovered matricellular protein, in H. pylori infection. Increased TINAGL1 production by gastric epithelial cells (GECs) in the infected gastric mucosa was synergistically induced by H. pylori and IL-1β via the ERK-SP1 pathway in a cagA-dependent manner. Elevated human gastric TINAGL1 correlated with H. pylori colonization and the severity of gastritis, and mouse TINAGL1 derived from non-bone marrow-derived cells promoted bacterial colonization and inflammation. Importantly, H. pylori colonization and inflammation were attenuated in Tinagl1−/− and Tinagl1ΔGEC mice and were increased in mice injected with mouse TINAGL1. Mechanistically, TINAGL1 suppressed CCL21 expression and promoted CCL2 production in GECs by directly binding to integrin α5β1 to inhibit ERK and activate the NF-κB pathway, respectively, which not only led to decreased gastric influx of moDCs via CCL21-CCR7-dependent migration and, as a direct consequence, reduced the bacterial clearance capacity of the H. pylori-specific Th1 response, thereby promoting H. pylori colonization, but also resulted in increased gastric influx of Ly6Chigh monocytes via CCL2-CCR2-dependent migration. In turn, TINAGL1 induced the production of the proinflammatory protein S100A11 by Ly6Chigh monocytes, promoting H. pylori-associated gastritis. In summary, we identified a model in which TINAGL1 collectively ensures H. pylori persistence and promotes gastritis. | Yongsheng Teng Rui Xie Jingyu Xu Pan Wang Wanyan Chen Zhiguo Shan Zongbao Yan Fangyuan Mao Ping Cheng Liusheng Peng Jinyu Zhang Wenqing Tian Shiming Yang Yongliang Zhao Weisan Chen Quanming Zou Yuan Zhuang | 2023 | Cellular & Molecular Immunology2023，20，8： | 1 |
| 11 | Development of photon beam position feedback system based on two PBPMs at HLS显示文摘In this paper,in order to stabilize the position and angle of the light source point,a new photon beam position feedback system based on the Photon Beam Position Monitors was developed on Hefei Light Source,and used to correct the position drift and angle variation of the light source at the same time.On introducing the feedback principle,the transfer function matrix is calibrated,indicating that the new system is workable and effective. | GU Liming SUN Baogen XUAN Ke YANG Yongliang LU Ping ZHOU Zeran CHENG Chaocai XU Hongliang | 2013 | Nuclear Science and Techniques2013，24，2： | 1 |
| 12 | Human immunodeficiency virus type 1 tat accelerates kaposi sarcoma-associated herpesvirus kaposin A-mediated tumorigenesis of transformed fibroblasts in vitro as well as in nude and immunocompetent mice显示文摘Kaposi sarcoma-associated herpesvirus(KSHV) is necessary but not sufficient to cause Kaposi sarcoma(KS).Coinfection with human immunodeficiency virus type 1(HIV-1), in the absence of antiretroviral suppressive therapy, drastically increases the risk of KS.Previously, we identified that HIV-1 transactivative transcription protein(Tat) was an important cofactor that activated lytic cycle replication of KSHV.Here, we further investigated the potential of Tat to influence tumorigenesis induced by KSHV Kaposin A, a product of KSHV that was encoded by the open reading frame K12(a KSHV-transforming gene).By using colony formation in soft agar, H-3-TdR incorporation, cell cycle, and microarray gene expression analyses, we demonstrated that Tat enhanced proliferation as well as mitogen-activated protein kinase, signal transducer and activator of transcription 3, and phosphatidylinositol 3-kinase/protein kinase B signaling induced by Kaposin A in NIH3T3 cells.Animal experiments further demonstrated that Tat accelerated tumorigenesis by Kaposin A in athymic nu/nu mice.Cells obtained from primary tumors of nude mice succeeded inducing tumors in immunocompetent mice.These data suggest that Tat can accelerate tumorigenesis induced by Kaposin A.Our data present the first line of evidence that Tat may participate in KS pathogenesis by collaborating with Kaposin A in acquired immunodeficiency syndrome(AIDS)-related KS(AIDS-KS) patients.Our data also suggest that the model for Kaposin and Tat-mediated oncogenesis will contribute to our understanding of the pathogenesis of AIDS-KS at the molecular level and may even be important in exploring a novel therapeutic method for AIDS-KS. | Chen, Xiuying Cheng, Lin Jia, Xuemei Yao, Shuihong Lv, Zhigang Qin, Di Fang, Xin Lu, Chun Nanjing Med Univ, Dept Microbiol & Immunol, Nanjing 210029, Peoples R China.Chen, Xiuying Lu, Chun Nanjing Med Univ, Lab Reprod Med, Nanjing 210029, Peoples R China.Chen, Xiuying Lu, Chun Nanjing Med Univ, Key Lab Pathogen Biol Jiangsu Prov, Nanjing 210029, Peoples R China.Chen, Xiuying Lu, Chun Key Lab Lab Med Jiangsu Prov, Nanjing 210029, Peoples R China.Chen, Xiuying Lei, Yongliang Lishui Ctr Dis Control & Prevent, Lishui 323000, Zhejiang, Peoples R China.Cheng, Lin Huanghe Sci & Technol Coll, Dept Microbiol & Immunol, Zhengzhou 450006, Peoples R China.Zeng, Yi Youjiang Med Coll Nationalities, Dept Microbiol & Immunol, Bose 533000, Peoples R China. | 2010 | 南京医科大学学报(自然科学版)2010，30，1： | 1 |
| 13 | The Influence of Preparation Parameters on the Mass Production of Vapor-grown Carbon Nanofibers显示文摘 | Fan Yueying Cheng Huiming Wei Yongliang | 2000 | Carbon2000，38，6： | 1 |
| 14 | Tailoring the Diameters of Vapor-grown Carbon Nanofibers显示文摘 | Fan Yueying Cheng Huiming Wei Yongliang | 2000 | Carbon2000，38，6： | 1 |
| 15 | Inactivated SARS-CoV-2 booster vaccine enhanced immune responses in patients with chronic liver diseases显示文摘Chronic liver disease(CLD)entails elevated risk of COVID-19 severity and mortality.The effectiveness of the booster dose of inactivated SARS-CoV-2 vaccine in stimulating antibody response in CLD patients is unclear.Therefore,we conducted a cross-sectional study involving 237 adult CLD patients and 170 healthy controls(HC)to analyze neutralizing antibodies(NAbs)against SARS-CoV-2 prototype and BA.4/5 variant,anti-receptor binding domain(RBD)IgG,and total anti-SARS-CoV-2 antibodies.Serum levels of the total anti-SARS-CoV-2 antibodies,anti-RBD IgG and inhibition efficacy of NAbs were significantly elevated in CLD patients after the booster dose compared with the pre-booster dose,but were relatively lower than those of HCs.Induced humoral responses decreased over time after booster vaccination.The neutralization efficiency of the serum against BA.4/5 increased but remained below the inhibition threshold.All four SARS-CoV-2 antibodies,including total anti-SARS-CoV-2 antibodies,anti-RBD IgG and NAbs against prototype and BA.4/5,were lower in patients with severe CLD than those with non-severe CLD.After booster shot,age and time after the last vaccine were the risk factors for seropositivity of NAb against BA.4/5 in CLD patients.Additionally,white blood cell counts and hepatitis B core antibodies were the protective factors,and severe liver disease was the risk factor associated with seropositivity of total anti-SARS-CoV-2 antibodies.Overall,our data uncovered that antibody responses were improved in CLD patients and peaked at 120 days after the booster vaccines.All antibodies excepting total anti-SARS-CoV-2 antibodies declined after peak.CLD patients exhibited impaired immunologic responses to vaccination and weakened NAbs against BA.4/5,which hindered the protective effect of the booster shot against Omicron prevalence.Cellular immune responses should be further evaluated to determine the optimal vaccine regimen for CLD patients. | Yongmei Liu Jianhua Lu Haoting Zhan Wenfang Yuan Xiaomeng Li Haiyan Kang Haolong Li Yongliang Chen Linlin Cheng Xingli Sun Haojie Zheng Wei Wang Erhei Dai Yongzhe Li | 2023 | Virologica Sinica2023，38，5： | 0 |
| 16 | Motor oil degradation during urban cycle road tests显示文摘Several civilian vehicles in China operate in urban traffic conditions and have their motor oil changed every 5,000 km.This study investigates the variations in oil properties after servicing at 5,000 km,based on systematic road tests(including a repeated test,a parallel test,and a new vehicle test).The physicochemical properties,changes in components,oxidation stability,detergent‐dispersant performance,and tribological properties of motor oils were analyzed.The results showed that the total acid number(TAN)of oils increased with the operation mileage,by up to 1.41 mgKOH/g.The total base number(TBN)decreased after the road tests were completed,and the decrease was less than 44.6%.The kinematic viscosity(KV)of most oils decreased initially and then stabilized in the middle stage,before starting to increase later in the experiment.The change in KV at 100℃was less than 15.96%.The oxidation onset temperature(OOT)of the oils diminished gradually with the operation mileage.All OOT values of the used oils were higher than 210℃.A spot test indicated that the used oils retained their detergentdispersant performance to an appropriate extent.The four‐ball wear scar diameters and friction coefficient of the used oils did not increase significantly after the road tests were completed.This study can serve as a reference for end‐users when changing motor oils. | Lei WEI Haitao DUAN Yongliang JIN Dan JIA Bingxue CHENG Jianfang LIU Jian LI | 2021 | Friction2021，9，5： | 0 |
| 17 | Construction of a Microsatellite-enriched Library of Rhododendron simsii Planch.显示文摘In this study,an( AG) n microsatellite-enriched library of Rhododendron simsii Planch. was constructed with FIASCO( fast Isolation by AFLP sequences containing repeats) method. Among 356 positive colonies verified by colony PCR of the( AG) n microsatellite-enriched library,233 colonies were selected for further sequencing. According to the results,202 colonies containing microsatellites were obtained,accounting for 86. 7%. Discarding sequences with miscellaneous peaks,overlapping peaks and weak signals,39 sequences were screened finally for subsequent primer exploitation,including 22 perfect type SSR loci,5 imperfect type SSR loci and 12 compound type SSR loci. The FIASCO method is efficient and feasible for constructing microsatellite-enriched libraries of Rhododendron spp.,which laid a solid foundation for isolation of microsatellite loci and investigation of genetic diversity and genetic structure of Rhododendron spp. | Shuzhen WANG Weibin JIN Jun XIANG Yongliang ZHENG Yuanping FANG Jianping GAN Hua CHENG Hang DU | 2015 | Agricultural Biotechnology2015，4，5： | 0 |
| 18 | The Anzhen Risk Scoring System for Acute Type A Aortic Dissection:A Prospective Observational Study Protocol显示文摘Introduction:Acute type A aortic dissection(ATAAD)is a catastrophic disease with fatal outcomes.Malperfusion syndrome(MPS)is a serious complication of ATAAD,with an incidence of 20–40%.Many studies have shown that MPS is the main risk factor for poor ATAAD prognosis.However,a risk scoring system for ATAAD based on MPS is lacking.Here,we designed a risk scoring system for ATAAD to assess mortality through quantitative assessment of relevant organ malperfusion and subsequently develop rational treatment strategies.Methods and analysis:This was a prospective observational study.Patients’perioperative clinical data were col-lected to establish a database of ATAAD(N≥3000)and determine whether these patients had malperfusion complica-tions.The Anzhen risk scoring system was established on the basis of organ malperfusion by using a random forest survival model and a logistics model.The better method was then chosen to establish a revised risk scoring system.Ethics and dissemination:This study received ethical approval from the Ethics Committees of Beijing Anzhen Hospital,Capital Medical University(KS2019034-1).Patient consent was waived because biological samples were not collected,and no patient rights were violated.Findings will be disseminated at scientific conferences and in peer-reviewed publications. | Bo Jia Cheng Luo Chengnan Li Yipeng Ge Yongliang Zhong Zhiyu Qiao Haiou Hu Suwei Chen Junming Zhu | 2023 | Cardiovascular Innovations and Applications2023，7，1： | 0 |
| 19 | Investigation on sampling artifacts of particle associated PAHs using ozone denuder systems显示文摘多不的芳香的烃(哼) 是作为重要 carcinogenic 被识别到人的健康的复杂有机化合物。哼(主要在粒子阶段) 产生大气的氧化剂气体,特别臭氧,氮氧化物(没有 < 潜水艇 class= “ a-plus-plus ” > x ), 氢氧根基(哦) ,并且能在采样过程期间在过滤器上被降级,导致低估周围哼集中。工作是调查联系的粒子的这的目标哼采样人工制品在北京的夏天由臭氧引起了。比较采样系统在整个运动期间同时被操作,有激活的碳臭氧 denuder 的,其它正在被使采样同样常规系统。激活的碳 denuder 被证明高度有效从空气溪流消除臭氧。一般来说,九粒子界限哼从常规刺绣花样观察了都是比从臭氧 denuder 的那些低的系统。总数哼(粒子阶段) 集中被 35.9% 平均在常规采样低估过程。Benzo [一] 分核(BaP ) 有集体损失的最高的百分比。周围的温度被成立穿上影响哼采样人工制品。联系的粒子的高温度罐头增加损失在采样期间哼。 | Kai LIU Fengkui DUAN Kebin HE Yongliang MA Yuan CHENG | 2014 | Frontiers of Environmental Science & Engineering2014，8，2： | 0 |
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